首页 > 最新文献

Lietuvos Chirurgija最新文献

英文 中文
Vallecular Cholesterol Granuloma: Case Report 山谷胆固醇颗粒瘤1例报告
Pub Date : 2023-05-02 DOI: 10.15388/lietchirur.2023.22.83
Jūratė Vertelytė, Arnoldas Morozas
Introduction. Cholesterol granuloma is a rare benign cystic neoplasm characterised by a fibrous capsule, and a cystic fluid containing cholesterol crystals, multinucleated giant cells, erythrocytes and haemosiderin. Cholesterol granulomas are usually found in diverse parts of the temporal bone, most commonly – petrous apex. Very few cases of cholesterol granulomas in other organs have been reported, to our knowledge none are reported in the larynx. The main purpose of this case report is to highlight this extremely rare laryngeal lesion and its unique macroscopic appearance. Case report. A 55-year-old man is referred to the Ear, Nose and Throat Centre because of persistent hoarseness, globus sensation and complicated intubation due to a mass in the larynx. Videolaryngoscopy showed a large cyst-like mass in the vallecula, epiglottis was displaced towards the posterior pharyngeal wall and erythema of interarytenoid notch and arytenoid tubercle was present. A computerized tomography scan confirmed a cystic mass on the lingual surface of the epiglottis. On the basis of the examination and clinical symptoms, a diagnosis of chronic laryngitis, gastro-oesophageal reflux and an unspecified benign tumour of the respiratory system was made, surgical treatment was planned. The patient underwent microlaryngoscopy and surgical extirpation of the cyst using a CO2 laser, as the cyst was opened a yellowish, shiny, viscous fluid was observed. Two days later, laryngoscopy revealed fibrin plaque at the site of the cyst. Final diagnosis of cholesterol granuloma was formed based on histological examination of the mass. Conclusions. Cholesterol granulomas and masses in vallecula are extremly rare, but this case shows that cholesterol granuloma can be included in the differential diagnosis of cystic neoplasms of the larynx.
介绍胆固醇肉芽肿是一种罕见的良性囊性肿瘤,其特征是纤维包膜和含有胆固醇晶体、多核巨细胞、红细胞和含铁血黄素的囊性液体。胆固醇肉芽肿通常出现在颞骨的不同部位,最常见的是岩尖。很少有其他器官胆固醇肉芽肿的病例报道,据我们所知,喉部没有胆固醇肉芽肿的报道。本病例报告的主要目的是强调这种极其罕见的喉部病变及其独特的宏观外观。病例报告。一名55岁的男子因持续的声音嘶哑、眼球感觉和喉部肿块导致的复杂插管而被转诊至耳鼻喉中心。喉镜检查显示,咽谷有一个巨大的囊肿样肿块,会厌向咽后壁移位,并出现红蛋白间切迹和杓状结节红斑。计算机断层扫描证实会厌舌表面有一个囊性肿块。根据检查和临床症状,诊断为慢性喉炎、胃食管反流和呼吸系统不明良性肿瘤,并计划进行手术治疗。患者接受了显微喉镜检查,并使用CO2激光手术摘除囊肿,当囊肿打开时,观察到黄色、有光泽、粘稠的液体。两天后,喉镜检查显示囊肿部位有纤维蛋白斑块。胆固醇肉芽肿的最终诊断是根据肿块的组织学检查形成的。结论:胆固醇肉芽肿和vallecula肿块极为罕见,但本例表明胆固醇肉芽肿可用于喉部囊性肿瘤的鉴别诊断。
{"title":"Vallecular Cholesterol Granuloma: Case Report","authors":"Jūratė Vertelytė, Arnoldas Morozas","doi":"10.15388/lietchirur.2023.22.83","DOIUrl":"https://doi.org/10.15388/lietchirur.2023.22.83","url":null,"abstract":"Introduction. Cholesterol granuloma is a rare benign cystic neoplasm characterised by a fibrous capsule, and a cystic fluid containing cholesterol crystals, multinucleated giant cells, erythrocytes and haemosiderin. Cholesterol granulomas are usually found in diverse parts of the temporal bone, most commonly – petrous apex. Very few cases of cholesterol granulomas in other organs have been reported, to our knowledge none are reported in the larynx. The main purpose of this case report is to highlight this extremely rare laryngeal lesion and its unique macroscopic appearance. Case report. A 55-year-old man is referred to the Ear, Nose and Throat Centre because of persistent hoarseness, globus sensation and complicated intubation due to a mass in the larynx. Videolaryngoscopy showed a large cyst-like mass in the vallecula, epiglottis was displaced towards the posterior pharyngeal wall and erythema of interarytenoid notch and arytenoid tubercle was present. A computerized tomography scan confirmed a cystic mass on the lingual surface of the epiglottis. On the basis of the examination and clinical symptoms, a diagnosis of chronic laryngitis, gastro-oesophageal reflux and an unspecified benign tumour of the respiratory system was made, surgical treatment was planned. The patient underwent microlaryngoscopy and surgical extirpation of the cyst using a CO2 laser, as the cyst was opened a yellowish, shiny, viscous fluid was observed. Two days later, laryngoscopy revealed fibrin plaque at the site of the cyst. Final diagnosis of cholesterol granuloma was formed based on histological examination of the mass. Conclusions. Cholesterol granulomas and masses in vallecula are extremly rare, but this case shows that cholesterol granuloma can be included in the differential diagnosis of cystic neoplasms of the larynx.","PeriodicalId":52926,"journal":{"name":"Lietuvos Chirurgija","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41870729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Internal Hernia Through Foramen of Winslow a Rare Cause of Small Bowel Obstruction: A Case Report Winslow Foramen内疝——一例罕见的小肠梗阻原因
Pub Date : 2023-05-02 DOI: 10.15388/lietchirur.2023.22.82
V. Nair, Malik Parmjit, Pawan Sharma, Sarali Santhosh Raja, Atreya Aprajita
Internal hernia through foramen of Winslow (FoW) is rare condition as there are only 200 cases reported so far in the literature. Our patient a 78 years man presented with a clinical picture suggestive of small bowel obstruction for 5 days. Patient underwent emergency laparotomy following suspicion of internal hernia on imaging. On exploratory laparotomy there was grossly dilated bowel loops and a small segment of terminal ileum and omentum was found herniating through FoW in to the lesser sac. The bowel segment was reduced with gentle traction and herniated segment of omentum was excised due to questionable viability. Opening of FoW was unusually large and to prevent hernia recurrence it was closed partially. Postoperative period was uneventful. This unusual case presented to us diagnostic confusion and management challenge considering the previous history, multiple comorbidities and geriatric profile.
温斯洛孔内疝是一种罕见的情况,因为到目前为止,文献中只有200例报道。我们的患者是一名78岁的男性,临床表现提示小肠梗阻5天。患者在影像学检查怀疑为内疝后,接受了紧急剖腹手术。在剖腹探查术中,发现肠环严重扩张,回肠末端和网膜的一小段通过FoW疝入小囊。用温和的牵引法缩小肠段,并切除因生存能力可疑而突出的网膜段。FoW的开口非常大,为了防止疝复发,它被部分关闭。术后情况平静。考虑到既往病史、多种合并症和老年特征,这个不寻常的病例给我们带来了诊断上的困惑和管理上的挑战。
{"title":"Internal Hernia Through Foramen of Winslow a Rare Cause of Small Bowel Obstruction: A Case Report","authors":"V. Nair, Malik Parmjit, Pawan Sharma, Sarali Santhosh Raja, Atreya Aprajita","doi":"10.15388/lietchirur.2023.22.82","DOIUrl":"https://doi.org/10.15388/lietchirur.2023.22.82","url":null,"abstract":"Internal hernia through foramen of Winslow (FoW) is rare condition as there are only 200 cases reported so far in the literature. Our patient a 78 years man presented with a clinical picture suggestive of small bowel obstruction for 5 days. Patient underwent emergency laparotomy following suspicion of internal hernia on imaging. On exploratory laparotomy there was grossly dilated bowel loops and a small segment of terminal ileum and omentum was found herniating through FoW in to the lesser sac. The bowel segment was reduced with gentle traction and herniated segment of omentum was excised due to questionable viability. Opening of FoW was unusually large and to prevent hernia recurrence it was closed partially. Postoperative period was uneventful. This unusual case presented to us diagnostic confusion and management challenge considering the previous history, multiple comorbidities and geriatric profile.","PeriodicalId":52926,"journal":{"name":"Lietuvos Chirurgija","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45035629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pancreatic Mucinous Cystic Neoplasm with Associated Invasive Carcinoma: A Case Report and Literature Review 胰腺粘液囊性肿瘤伴浸润性癌1例报告及文献复习
Pub Date : 2023-05-02 DOI: 10.15388/lietchirur.2023.22.84
Kristina Marcinkevičiūtė, Dignė Jurkevičiūtė, Rokas Stulpinas, E. Stratilatovas, A. Dulskas
Background. Pancreatic mucinous cystic neoplasm (PMCN) with associated invasive carcinoma is a rare entity. According to the World Health Organisation (WHO) 2010, PMCN with associated invasive carcinoma is referred to the malignant lesions of the pancreatic epithelial tumour. Case report. A 52-year-old female patient presented with pain in the umbilical and epigastric regions for 5 months and noticed a solid visible tumour on the left side of the abdomen 3 months ago when she lied down. The level of the CA125 was 47.64 U/ml (normal value <35 U/ml). Abdominal and pelvic magnetic resonance imaging (MRI) showed a cystic multiseptal mass in the left iliac region, defined as a left ovary tumour, while Computed tomography scan revealed a cystic tumour of the pancreatic tail. The patient underwent a resection of the pancreatic tail with a 20 cm cystic solid tumour, splenectomy and left hemicolectomy. Histopathology report confirmed mucinous cystic neoplasm of the pancreatic tail with associated invasive carcinoma (combined badly differentiated (G3) ductal (40%) and undifferentiated (G4) anaplastic (60%) carcinoma) pT1bN0. Postoperative course complicated with wound infection. The patient was discharged on postoperative day 10. The patient is still alive 2 years on follow-up. Conclusions. PMCN with associated invasive carcinomas are rare lesions of pancreas with relatively benign course. This malignant pancreatic tumour displays morphologies as pleomorphic epithelial cells and relatively mononuclear spindle cells, and not always tends to have underlying ovarian type stroma. The comprehensive histopathological examination of the tumour is necessary in order to cure most MCN patients with minimally invasive types.
背景胰腺粘液性囊性肿瘤(PMCN)伴浸润性癌是一种罕见的肿瘤。根据世界卫生组织(世界卫生组织)2010,PMCN与相关侵袭性癌是指胰腺上皮肿瘤的恶性病变。病例报告。一名52岁的女性患者出现脐部和上腹部疼痛5个月,3个月前躺下时发现腹部左侧有一个可见的实体肿瘤。CA125水平为47.64U/ml(正常值<35U/ml)。腹部和骨盆磁共振成像(MRI)显示左髂区有一个囊性多节段肿块,被定义为左卵巢肿瘤,而计算机断层扫描显示胰腺尾部有一个囊状肿瘤。患者接受了胰腺尾部20厘米囊性实体瘤切除术、脾切除术和左半结肠切除术。组织病理学报告证实胰腺尾部黏液性囊性肿瘤伴浸润性癌(严重分化(G3)导管(40%)和未分化(G4)间变性(60%)合并癌)pT1bN0。术后并发伤口感染。患者于术后第10天出院。经过随访,患者仍存活2年。结论。伴有浸润性癌的PMCN是胰腺的罕见病变,病程相对良性。这种恶性胰腺肿瘤表现为多形性上皮细胞和相对单核梭形细胞,并不总是有潜在的卵巢型间质。为了治愈大多数微创型MCN患者,有必要对肿瘤进行全面的组织病理学检查。
{"title":"Pancreatic Mucinous Cystic Neoplasm with Associated Invasive Carcinoma: A Case Report and Literature Review","authors":"Kristina Marcinkevičiūtė, Dignė Jurkevičiūtė, Rokas Stulpinas, E. Stratilatovas, A. Dulskas","doi":"10.15388/lietchirur.2023.22.84","DOIUrl":"https://doi.org/10.15388/lietchirur.2023.22.84","url":null,"abstract":"Background. Pancreatic mucinous cystic neoplasm (PMCN) with associated invasive carcinoma is a rare entity. According to the World Health Organisation (WHO) 2010, PMCN with associated invasive carcinoma is referred to the malignant lesions of the pancreatic epithelial tumour. Case report. A 52-year-old female patient presented with pain in the umbilical and epigastric regions for 5 months and noticed a solid visible tumour on the left side of the abdomen 3 months ago when she lied down. The level of the CA125 was 47.64 U/ml (normal value <35 U/ml). Abdominal and pelvic magnetic resonance imaging (MRI) showed a cystic multiseptal mass in the left iliac region, defined as a left ovary tumour, while Computed tomography scan revealed a cystic tumour of the pancreatic tail. The patient underwent a resection of the pancreatic tail with a 20 cm cystic solid tumour, splenectomy and left hemicolectomy. Histopathology report confirmed mucinous cystic neoplasm of the pancreatic tail with associated invasive carcinoma (combined badly differentiated (G3) ductal (40%) and undifferentiated (G4) anaplastic (60%) carcinoma) pT1bN0. Postoperative course complicated with wound infection. The patient was discharged on postoperative day 10. The patient is still alive 2 years on follow-up. Conclusions. PMCN with associated invasive carcinomas are rare lesions of pancreas with relatively benign course. This malignant pancreatic tumour displays morphologies as pleomorphic epithelial cells and relatively mononuclear spindle cells, and not always tends to have underlying ovarian type stroma. The comprehensive histopathological examination of the tumour is necessary in order to cure most MCN patients with minimally invasive types.","PeriodicalId":52926,"journal":{"name":"Lietuvos Chirurgija","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47211498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Triple Test in Evaluating Breast Lumps 三重试验在评估乳腺肿块中的作用
Pub Date : 2023-05-02 DOI: 10.15388/lietchirur.2023.22.81
S. Iqbal, Saima Tabassum, Z. Khan
Breast tissue undergoes constant physiological changes in a woman’s life because of influence of endocrine hormones during and after reproductive life. These changes may present as pain, lumpiness or both in the breast. Breast lumps are feared for cancer. Thus, it is important for women with a breast lump to receive appropriate evaluation. Clinical breast examination is first step in evaluation of breast lump. The diagnostic sensitivity of clinical breast examination is high (98%) whereas its specificity is low, averaging 48%. Ultrasound is preferred in evaluation of radiologically dense breasts and in the study of breasts with augmentation mammoplasties. Micro-calcifications on mammography are considered to be important signs of breast cancer. X-ray mammography detects microcalcifications in 30–50% of breast cancers. FNAC is a cheap, cost effective and readily available routine diagnostic with a sensitivity ranging between 89% to 98% and specificity between 98% to 100% for palpable breast lumps. When combined together triple test achieves a higher sensitivity, specificity and diagnostic accuracy than any of the investigations taken alone. We conducted a prospective study to evaluate breast masses by clinical assessment, imaging and pathological examination. Results were compared with histopathology. We concluded that triple assessment in breast lumps gives superior results than any of its modalities taken alone.
在妇女的一生中,由于生殖期间和生殖后内分泌激素的影响,乳房组织经历了不断的生理变化。这些变化可能表现为乳房疼痛、肿块或两者兼而有之。乳房肿块被认为是癌症。因此,有乳房肿块的妇女接受适当的评估是很重要的。临床乳腺检查是评估乳腺肿块的第一步。临床乳腺检查诊断敏感性高(98%),特异性低(平均48%)。超声是首选在评估放射致密的乳房和乳房隆胸术的研究。乳房x光检查中的微钙化被认为是乳腺癌的重要征兆。在30-50%的乳腺癌中,x射线乳房x光检查可发现微钙化。FNAC是一种廉价、经济且容易获得的常规诊断方法,对于可触及的乳房肿块,其灵敏度在89%至98%之间,特异性在98%至100%之间。当结合在一起三重测试达到更高的灵敏度,特异性和诊断准确性比任何单独采取的调查。我们进行了一项前瞻性研究,通过临床评估,影像学和病理检查来评估乳房肿块。结果与组织病理学比较。我们的结论是,乳房肿块的三重评估比单独采取任何方式都有更好的结果。
{"title":"Role of Triple Test in Evaluating Breast Lumps","authors":"S. Iqbal, Saima Tabassum, Z. Khan","doi":"10.15388/lietchirur.2023.22.81","DOIUrl":"https://doi.org/10.15388/lietchirur.2023.22.81","url":null,"abstract":"Breast tissue undergoes constant physiological changes in a woman’s life because of influence of endocrine hormones during and after reproductive life. These changes may present as pain, lumpiness or both in the breast. Breast lumps are feared for cancer. Thus, it is important for women with a breast lump to receive appropriate evaluation. Clinical breast examination is first step in evaluation of breast lump. The diagnostic sensitivity of clinical breast examination is high (98%) whereas its specificity is low, averaging 48%. Ultrasound is preferred in evaluation of radiologically dense breasts and in the study of breasts with augmentation mammoplasties. Micro-calcifications on mammography are considered to be important signs of breast cancer. X-ray mammography detects microcalcifications in 30–50% of breast cancers. FNAC is a cheap, cost effective and readily available routine diagnostic with a sensitivity ranging between 89% to 98% and specificity between 98% to 100% for palpable breast lumps. \u0000When combined together triple test achieves a higher sensitivity, specificity and diagnostic accuracy than any of the investigations taken alone. We conducted a prospective study to evaluate breast masses by clinical assessment, imaging and pathological examination. Results were compared with histopathology. We concluded that triple assessment in breast lumps gives superior results than any of its modalities taken alone.","PeriodicalId":52926,"journal":{"name":"Lietuvos Chirurgija","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47801648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of Sentinel Lymph Nodes During Breast Cancer Surgery: A Literature Overview 乳腺癌手术中前哨淋巴结的检测:文献综述
Pub Date : 2023-03-29 DOI: 10.15388/lietchirur.2023.22.73
G. Šepetys, D. Gudavičienė, N. Jakutis
Introduction. Detecting metastases is an important part of successful breast cancer treatment. Usually, the tumor tissue first spreads to the sentinel lymph nodes. Removal of the latter during surgery and histological examination allows to assess the patient’s di­sease stage, prognosis and treatment. The literature provides more than one approach or a combination of them, allowing us to accurately identify the breast’s sentinel lymph nodes and avoid removing all axillary lymph nodes. Purpose. To review the methods of intraoperative detection of breast sentinel lymph nodes presented in the literature. Research material and methods. Publications were searched using the specialized information search system Google Scholar. Keywords used in the search: breast sentinel lymph nodes, intraoperative detection. After evaluating the exclusion criteria, the review was based on 25 scientific publications. Results. 4 individual measures and 2 combinations of them can be used to detect sentinel breast lymph nodes during surgery. The materials used can be injected in 6 different ways. Conclusions. The combination of technetium-99m radiocolloid and methylene blue can be evaluated as the best method for intraoperative detection of sentinel lymph nodes in breast cancer patients. On the other hand, due to radiation and operating costs, more attention is being paid to the use of indocyanine green, superparamagnetic iron oxide, methylene blue dye, and the detection of metastases without surgery. Superficial methods of injecting the substance should be combined with deep ones due to the possibility of detecting extra-axillary sentinel lymph nodes of the breast. Ultimately, all decisions must be made on a case-by-case basis.
介绍。检测转移是成功治疗乳腺癌的重要组成部分。通常,肿瘤组织首先扩散到前哨淋巴结。在手术和组织学检查中切除后者可以评估患者的疾病分期、预后和治疗。文献提供了多种方法或它们的组合,使我们能够准确地识别乳房前哨淋巴结,避免切除所有腋窝淋巴结。目的。回顾文献中关于术中乳腺前哨淋巴结的检测方法。研究材料和方法。使用专业信息检索系统谷歌Scholar检索出版物。搜索关键词:乳腺前哨淋巴结,术中检测。在评估了排除标准后,该综述以25份科学出版物为基础。结果:术中检测前哨淋巴结可采用4种单项方法和2种组合方法。所使用的材料可以通过6种不同的方式注入。结论。锝-99m放射性胶体联合亚甲基蓝可被评价为乳腺癌患者术中前哨淋巴结检测的最佳方法。另一方面,由于辐射和手术费用的原因,越来越多的人关注吲哚菁绿、超顺磁性氧化铁、亚甲基蓝染料的使用,以及无需手术检测转移的方法。由于有可能发现乳腺腋外前哨淋巴结,浅表注射方法应与深部注射方法相结合。最终,所有的决定都必须在个案的基础上做出。
{"title":"Detection of Sentinel Lymph Nodes During Breast Cancer Surgery: A Literature Overview","authors":"G. Šepetys, D. Gudavičienė, N. Jakutis","doi":"10.15388/lietchirur.2023.22.73","DOIUrl":"https://doi.org/10.15388/lietchirur.2023.22.73","url":null,"abstract":"Introduction. Detecting metastases is an important part of successful breast cancer treatment. Usually, the tumor tissue first spreads to the sentinel lymph nodes. Removal of the latter during surgery and histological examination allows to assess the patient’s di­sease stage, prognosis and treatment. The literature provides more than one approach or a combination of them, allowing us to accurately identify the breast’s sentinel lymph nodes and avoid removing all axillary lymph nodes. Purpose. To review the methods of intraoperative detection of breast sentinel lymph nodes presented in the literature. Research material and methods. Publications were searched using the specialized information search system Google Scholar. Keywords used in the search: breast sentinel lymph nodes, intraoperative detection. After evaluating the exclusion criteria, the review was based on 25 scientific publications. Results. 4 individual measures and 2 combinations of them can be used to detect sentinel breast lymph nodes during surgery. The materials used can be injected in 6 different ways. Conclusions. The combination of technetium-99m radiocolloid and methylene blue can be evaluated as the best method for intraoperative detection of sentinel lymph nodes in breast cancer patients. On the other hand, due to radiation and operating costs, more attention is being paid to the use of indocyanine green, superparamagnetic iron oxide, methylene blue dye, and the detection of metastases without surgery. Superficial methods of injecting the substance should be combined with deep ones due to the possibility of detecting extra-axillary sentinel lymph nodes of the breast. Ultimately, all decisions must be made on a case-by-case basis.","PeriodicalId":52926,"journal":{"name":"Lietuvos Chirurgija","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44724207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does Previous Perianal Surgery for Benign Diseases Have an Impact on Timing of Hospital Admission in Patients with Colorectal Cancer? 以前的良性疾病肛门周围手术对癌症结直肠癌患者住院时间有影响吗?
Pub Date : 2023-03-29 DOI: 10.15388/lietchirur.2023.22.65
Ali Sapmaz, C. Çelik, Murat Özgür Kılıç, H. Bolukbasi, S. Yılmaz
Objective. Colorectal cancer (CRC) is one of the most common and fatal malignancies worldwide. Although the clinical presentation varies according to the location of the tumor, hematochezia, tenesmus, changes in the defecation habit, chronic constipation, abdominal pain, and distension are the most common findings of CRCs. We aimed to investigate whether patients with CRC who had a surgical history for benign anal disease have more negative tumoral features or not. Material and Methods. Two-hundred fifty two patients who underwent surgery for CRC between 2010 and 2016 at general surgery clinic in Ankara Numune Training and Research Hospital included in this study. Patients were classified into two groups; patients who had undergone surgery for benign perianal disease such as hemorrhoid, anal fissure, perianal abscess and fistulae (Group 1) and patients without past history for perianal surgery (Group 2). Results. A total of 252 CRC patients with a mean age of 64.2 years were included in the study. There were 95 (37.7%) females and 157 (62.3%) males. There were 25 (9.9%) patients who had surgical history for benign perianal disease. There were no statistically differences in tumor size, lymph node positivity, presence of distant metastasis, and tumor stage between the groups (p > 0.05). Conclusion. Although not statistically significant, CRC patients with a history of surgery for benign perianal disease had less lymphatic metastases and tumor size than those without prior perianal surgery. We think that this finding is important in that it indicates the importance of detailed and appropriate evaluation of patients with CRC.
客观的癌症是世界范围内最常见、最致命的恶性肿瘤之一。尽管临床表现因肿瘤位置而异,但便血、里急后重、排便习惯改变、慢性便秘、腹痛和腹胀是CRC最常见的表现。我们的目的是调查有良性肛门疾病手术史的CRC患者是否有更多的阴性肿瘤特征。材料和方法。本研究纳入了2010年至2016年间在安卡拉努穆恩培训研究医院普通外科诊所接受CRC手术的二百五十二名患者。将患者分为两组;曾接受过痔疮、肛裂、肛周脓肿和瘘管等良性肛周疾病手术的患者(第1组)和既往无肛周手术史的患者(2组)。结果。本研究共纳入252名CRC患者,平均年龄64.2岁。其中女性95例(37.7%),男性157例(62.3%)。有25例(9.9%)患者有良性肛周疾病的手术史。两组之间在肿瘤大小、淋巴结阳性率、远处转移的存在和肿瘤分期方面没有统计学差异(p>0.05)。结论:尽管没有统计学意义,但有良性肛周疾病手术史的CRC患者的淋巴转移和肿瘤大小比未经肛周手术的患者少。我们认为这一发现很重要,因为它表明了对CRC患者进行详细和适当评估的重要性。
{"title":"Does Previous Perianal Surgery for Benign Diseases Have an Impact on Timing of Hospital Admission in Patients with Colorectal Cancer?","authors":"Ali Sapmaz, C. Çelik, Murat Özgür Kılıç, H. Bolukbasi, S. Yılmaz","doi":"10.15388/lietchirur.2023.22.65","DOIUrl":"https://doi.org/10.15388/lietchirur.2023.22.65","url":null,"abstract":"Objective. Colorectal cancer (CRC) is one of the most common and fatal malignancies worldwide. Although the clinical presentation varies according to the location of the tumor, hematochezia, tenesmus, changes in the defecation habit, chronic constipation, abdominal pain, and distension are the most common findings of CRCs. We aimed to investigate whether patients with CRC who had a surgical history for benign anal disease have more negative tumoral features or not. Material and Methods. Two-hundred fifty two patients who underwent surgery for CRC between 2010 and 2016 at general surgery clinic in Ankara Numune Training and Research Hospital included in this study. Patients were classified into two groups; patients who had undergone surgery for benign perianal disease such as hemorrhoid, anal fissure, perianal abscess and fistulae (Group 1) and patients without past history for perianal surgery (Group 2). Results. A total of 252 CRC patients with a mean age of 64.2 years were included in the study. There were 95 (37.7%) females and 157 (62.3%) males. There were 25 (9.9%) patients who had surgical history for benign perianal disease. There were no statistically differences in tumor size, lymph node positivity, presence of distant metastasis, and tumor stage between the groups (p > 0.05). Conclusion. Although not statistically significant, CRC patients with a history of surgery for benign perianal disease had less lymphatic metastases and tumor size than those without prior perianal surgery. We think that this finding is important in that it indicates the importance of detailed and appropriate evaluation of patients with CRC.","PeriodicalId":52926,"journal":{"name":"Lietuvos Chirurgija","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44258291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Treatment of Stenosing Tenosynovitis: Early and Late Outcomes, Complications 狭窄性腱鞘炎的手术治疗:早期和晚期结局,并发症
Pub Date : 2023-03-29 DOI: 10.15388/lietchirur.2023.22.66
Karolis Varkalys, Saulius Knystautas, Kęstutis Braziulis, Vytautas Tamaliūnas, E. Zacharevskij
Background. The thickening of A1 pulley of the tendon sheath limits the excursion of flexor tendon. Stenosing tenosynovitis causes finger movements dysfunction and pain. Objective. To analyze early and late outcomes of patients with stenosing tenosynovitis after surgical treatment – anulotomy. Methods. All patients had standard surgical procedure – open anulotomy of A1 pulley. Pain (verbal pain scale), hand and arm function (QuickDASH) and complications were recorded before surgery, after 1 week, 3 months and 6 months post surgery. Results. There were 45 patients, 29 (64%) female, 16 (36%) male. The highest pain score was recorded before surgery median 5 (IQR 5). The lowest pain score median 2 (IQR 2) was recorded after 6 months post surgery. The difference of the results after 1 week, 3 months and 6 months was statistically significant p < 0.001. The worst hand and arm function was before surgery and 1 week post surgery. Accordingly: medians 52 (IQR 33) and 52 (IQR 35). Full hand function recovery was noticed after 6 months post surgery median 0 (IQR 11). The difference is statistically significant p < 0.001. Conclusions. Surgical treatment, open anulotomy is one of the most effective methods for stenosing tenosynovitis. After this procedure pain and hand function improves greatly. However, for some patients it might cause discomfort of the hand because of the scar’s sensitivity and location.
背景。肌腱鞘A1滑轮的增厚限制了屈肌腱的移位。狭窄性腱鞘炎引起手指运动功能障碍和疼痛。目标。目的:分析狭窄性腱鞘炎手术治疗后的早期和晚期预后。方法。所有患者均行标准手术- A1滑轮开腹环切开术。术前、术后1周、术后3个月、术后6个月分别记录疼痛(言语疼痛量表)、手、臂功能(QuickDASH)及并发症。结果。患者45例,女性29例(64%),男性16例(36%)。术前疼痛评分中位数5 (IQR 5)为最高,术后6个月疼痛评分中位数2 (IQR 2)为最低。治疗1周、3个月、6个月的结果差异有统计学意义p < 0.001。手术前和术后1周手、臂功能最差。据此:中位数52 (IQR 33)和52 (IQR 35)。术后6个月全手功能恢复中位数0 (IQR 11)。差异有统计学意义p < 0.001。结论。手术治疗中,开放性环切术是治疗狭窄性腱鞘炎最有效的方法之一。手术后疼痛和手部功能大大改善。然而,对于一些患者来说,由于疤痕的敏感性和位置,它可能会导致手部不适。
{"title":"Surgical Treatment of Stenosing Tenosynovitis: Early and Late Outcomes, Complications","authors":"Karolis Varkalys, Saulius Knystautas, Kęstutis Braziulis, Vytautas Tamaliūnas, E. Zacharevskij","doi":"10.15388/lietchirur.2023.22.66","DOIUrl":"https://doi.org/10.15388/lietchirur.2023.22.66","url":null,"abstract":"Background. The thickening of A1 pulley of the tendon sheath limits the excursion of flexor tendon. Stenosing tenosynovitis causes finger movements dysfunction and pain. Objective. To analyze early and late outcomes of patients with stenosing tenosynovitis after surgical treatment – anulotomy. Methods. All patients had standard surgical procedure – open anulotomy of A1 pulley. Pain (verbal pain scale), hand and arm function (QuickDASH) and complications were recorded before surgery, after 1 week, 3 months and 6 months post surgery. Results. There were 45 patients, 29 (64%) female, 16 (36%) male. The highest pain score was recorded before surgery median 5 (IQR 5). The lowest pain score median 2 (IQR 2) was recorded after 6 months post surgery. The difference of the results after 1 week, 3 months and 6 months was statistically significant p < 0.001. The worst hand and arm function was before surgery and 1 week post surgery. Accordingly: medians 52 (IQR 33) and 52 (IQR 35). Full hand function recovery was noticed after 6 months post surgery median 0 (IQR 11). The difference is statistically significant p < 0.001. Conclusions. Surgical treatment, open anulotomy is one of the most effective methods for stenosing tenosynovitis. After this procedure pain and hand function improves greatly. However, for some patients it might cause discomfort of the hand because of the scar’s sensitivity and location.","PeriodicalId":52926,"journal":{"name":"Lietuvos Chirurgija","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48425484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reliability of the Lymph Node Ratio in the Prediction of Gastric Cancer Survival 淋巴结比率在预测癌症生存率中的可靠性
Pub Date : 2023-03-29 DOI: 10.15388/lietchirur.2023.22.68
S. Kamalı, Cemal Ulusoy, G. Kamali
Background. Lymph node metastasis is the major determinant factor in the prognosis of gastric cancer. There is still no definite consensus on the lymph node number that should be harvested during gastric cancer surgery. Lymph Node Ratio (LNR) is defined as the ratio of metastatic nodes to the total number of pathologically examined lymph nodes. LNR has been proposed to be a sensitive prognostic factor in patients with gastric cancer. In this study the reliability of the LNR is tested for being a prognostic factor in gastric cancer survival. Methods. Medical records of 244 patients, with neither distant metastases nor neoadjuvant treatment underwent curative gastrectomy, were analyzed retrospectively in terms of survival according to the lymph node ratio (LNR). Patients were divided in two groups by using LNR cut-off value. Results. LNR of 0.4 was proved to be the best cut-off value to predict the prognosis of patients with gastric cancer. Univariate and multivariate analysis revealed that age over 65 (p < 0.001), and LNR ≥ 0.4 (p = 0.02) were independent factors in gastric cancer survival. Patients with LNR ≥ 0.4 presented with worse outcomes regarding other prognostic parameters (tumor differentiation, tumor diameter, lymphovascular invasion or perineural invasion), despite similar numbers of lymph nodes being harvested in both groups during surgery. Conclusion. Lymph node ratio is a reliable parameter to predict the survival in gastric cancer.
背景。淋巴结转移是胃癌预后的主要决定因素。对于胃癌手术中应该切除的淋巴结数目,目前还没有明确的共识。淋巴结比率(LNR)定义为转移淋巴结与病理检查淋巴结总数的比率。LNR被认为是胃癌患者预后的敏感因素。本研究检验了LNR作为胃癌生存预后因素的可靠性。方法。根据淋巴结比(LNR),回顾性分析244例无远处转移或新辅助治疗的根治性胃切除术患者的病历。采用LNR临界值将患者分为两组。结果。LNR为0.4是预测胃癌患者预后的最佳临界值。单因素和多因素分析显示,年龄大于65岁(p < 0.001)、LNR≥0.4 (p = 0.02)是影响胃癌生存的独立因素。LNR≥0.4的患者在其他预后参数(肿瘤分化、肿瘤直径、淋巴血管侵犯或神经周围侵犯)方面的预后较差,尽管两组患者在手术过程中淋巴结数量相似。结论。淋巴结比例是预测胃癌生存率的可靠指标。
{"title":"Reliability of the Lymph Node Ratio in the Prediction of Gastric Cancer Survival","authors":"S. Kamalı, Cemal Ulusoy, G. Kamali","doi":"10.15388/lietchirur.2023.22.68","DOIUrl":"https://doi.org/10.15388/lietchirur.2023.22.68","url":null,"abstract":"Background. Lymph node metastasis is the major determinant factor in the prognosis of gastric cancer. There is still no definite consensus on the lymph node number that should be harvested during gastric cancer surgery. Lymph Node Ratio (LNR) is defined as the ratio of metastatic nodes to the total number of pathologically examined lymph nodes. LNR has been proposed to be a sensitive prognostic factor in patients with gastric cancer. In this study the reliability of the LNR is tested for being a prognostic factor in gastric cancer survival. Methods. Medical records of 244 patients, with neither distant metastases nor neoadjuvant treatment underwent curative gastrectomy, were analyzed retrospectively in terms of survival according to the lymph node ratio (LNR). Patients were divided in two groups by using LNR cut-off value. Results. LNR of 0.4 was proved to be the best cut-off value to predict the prognosis of patients with gastric cancer. Univariate and multivariate analysis revealed that age over 65 (p < 0.001), and LNR ≥ 0.4 (p = 0.02) were independent factors in gastric cancer survival. Patients with LNR ≥ 0.4 presented with worse outcomes regarding other prognostic parameters (tumor differentiation, tumor diameter, lymphovascular invasion or perineural invasion), despite similar numbers of lymph nodes being harvested in both groups during surgery. Conclusion. Lymph node ratio is a reliable parameter to predict the survival in gastric cancer.","PeriodicalId":52926,"journal":{"name":"Lietuvos Chirurgija","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48788618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cystic Artery Control with Bipolar Electrocauterization During Laparoscopic Cholecystectomy 腹腔镜胆囊切除术中双极电凝控制膀胱动脉
Pub Date : 2023-03-29 DOI: 10.15388/lietchirur.2023.22.67
S. Iqbal, Saima Tabassum
Laparoscopic cholecystectomy is a widely practiced procedure for symptomatic cholelithiasis. Haemostasis of cystic artery can be achieved with clips electrocautery and ultra modern vessel sealing energy devices. Bipolar electro coagulation of cystic artery is safe and a cost effective measure in developing countries. Our aim was to establish the feasibility of bipolar electrocautery in securing cystic artery. We conducted a prospective study on 120 patients in different age and sex groups. Correctable co morbidities were not a contraindication to inclusion criteria. Anatomical variations in size, origin and number of cystic artery were noted.
腹腔镜胆囊切除术是一种广泛应用的治疗症状性胆结石的手术。囊性动脉止血可以通过夹式电烙器和超现代的血管密封能量装置来实现。双极电凝治疗囊性动脉在发展中国家是安全且经济有效的措施。我们的目的是确定双极电刀在固定囊性动脉方面的可行性。我们对120名不同年龄和性别的患者进行了前瞻性研究。可纠正的合并症不是纳入标准的禁忌症。囊性动脉的大小、起源和数量在解剖学上存在差异。
{"title":"Cystic Artery Control with Bipolar Electrocauterization During Laparoscopic Cholecystectomy","authors":"S. Iqbal, Saima Tabassum","doi":"10.15388/lietchirur.2023.22.67","DOIUrl":"https://doi.org/10.15388/lietchirur.2023.22.67","url":null,"abstract":"Laparoscopic cholecystectomy is a widely practiced procedure for symptomatic cholelithiasis. Haemostasis of cystic artery can be achieved with clips electrocautery and ultra modern vessel sealing energy devices. Bipolar electro coagulation of cystic artery is safe and a cost effective measure in developing countries. Our aim was to establish the feasibility of bipolar electrocautery in securing cystic artery. We conducted a prospective study on 120 patients in different age and sex groups. Correctable co morbidities were not a contraindication to inclusion criteria. Anatomical variations in size, origin and number of cystic artery were noted.","PeriodicalId":52926,"journal":{"name":"Lietuvos Chirurgija","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46196442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paauglio politrauma žemdirbystės pramonėje: klinikinio atvejo analizė 农业部门的增长:临床案例分析
Pub Date : 2023-03-29 DOI: 10.15388/lietchirur.2023.22.69
Kamilė Bagdonaitė, Emilija Sugintaitė, Inga Dekerytė, Aušra Lukošiūtė-Urbonienė, Artūras Kilda
Polytrauma is a condition when a patient has sustained multiple injuries, which can lead to disability or death. While the agriculture industry is growing, the number of polytrauma patients in children is increasing as well. It is high-energy traumas when it is important to immediately assess injuries and life-threatening conditions and to start trauma protocols guided treatment. In this article, we present a case of a 17-year-old boy who suffered extensive injuries caused by a straw pellets machine. We discussed the importance of prehospital care, multidisciplinary team involvement, and treatment methods.
多发性创伤是指患者遭受多处伤害,可能导致残疾或死亡。在农业发展的同时,儿童多发性创伤患者的数量也在增加。当立即评估损伤和危及生命的情况并开始创伤方案指导治疗很重要时,这就是高能创伤。在这篇文章中,我们介绍了一个17岁男孩的案例,他因秸秆颗粒机而受了大面积伤害。我们讨论了院前护理、多学科团队参与和治疗方法的重要性。
{"title":"Paauglio politrauma žemdirbystės pramonėje: klinikinio atvejo analizė","authors":"Kamilė Bagdonaitė, Emilija Sugintaitė, Inga Dekerytė, Aušra Lukošiūtė-Urbonienė, Artūras Kilda","doi":"10.15388/lietchirur.2023.22.69","DOIUrl":"https://doi.org/10.15388/lietchirur.2023.22.69","url":null,"abstract":"Polytrauma is a condition when a patient has sustained multiple injuries, which can lead to disability or death. While the agriculture industry is growing, the number of polytrauma patients in children is increasing as well. It is high-energy traumas when it is important to immediately assess injuries and life-threatening conditions and to start trauma protocols guided treatment. In this article, we present a case of a 17-year-old boy who suffered extensive injuries caused by a straw pellets machine. We discussed the importance of prehospital care, multidisciplinary team involvement, and treatment methods.","PeriodicalId":52926,"journal":{"name":"Lietuvos Chirurgija","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47761625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Lietuvos Chirurgija
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1