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Trophoblastic Disease: Review of the Literature 滋养性疾病:文献综述
Pub Date : 2022-05-02 DOI: 10.15388/lietchirur.2022.21.60
Gabrielė Launikonytė, Klaudija Korsakaitė, D. Bužinskienė
The purpose of this literature review is to discuss the most effective gestational trophoblastic disease diagnostic and treatment methods. Also, to introduce some of the novel treatment options currently being explored. A comprehensive research was carried out on scientific databases of MEDLINE and PubMed over the time period of 2014 to 2021. According to literature sources initial gestational trophoblastic disease diagnosis is multimodal: encompassing clinical features, quantitative human chorionic gonadotropin titers and pelvic ultrasonography. Pelvic magnetic resonance imaging, body computed tomography, chest radiography and angiography are the methods usually used for overall disease staging and metastases detection. The best treatment method is designated with reference to individual features of the patient and the disease. Conventional treatment consists of hysterectomy and chemotherapy; however, the use of new methods, such as directed enzyme prodrug therapy is also being attempted to cure metastasized and/or resistant gestational trophoblastic neoplasias. Most women with gestational trophoblastic disease can be successfully managed with preservation of reproductive function due to early diagnosis in the first trimester of pregnancy. It is important to identify gestational trophoblastic disease promptly and adjust specific treatment for every patient properly to minimize various complications.
本文献综述的目的是探讨最有效的妊娠滋养细胞疾病诊断和治疗方法。此外,介绍目前正在探索的一些新的治疗方案。在2014年至2021年期间,对MEDLINE和PubMed的科学数据库进行了全面研究。根据文献来源,最初的妊娠滋养细胞疾病诊断是多模式的:包括临床特征、定量人绒毛膜促性腺激素滴度和盆腔超声检查。盆腔磁共振成像、身体计算机断层扫描、胸部造影和血管造影术是通常用于疾病整体分期和转移检测的方法。最佳治疗方法是根据患者和疾病的个体特征来指定的。常规治疗包括子宫切除术和化疗;然而,新方法的使用,如定向酶前药治疗,也被尝试治疗转移和/或耐药的妊娠滋养细胞肿瘤。由于在妊娠早期诊断,大多数患有妊娠滋养细胞疾病的女性可以在保留生殖功能的情况下成功治疗。及时发现妊娠滋养细胞疾病并适当调整每一位患者的具体治疗以最大限度地减少各种并发症是很重要的。
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引用次数: 0
Xth Triennial Meeting of the Lithuanian Society of Coloproctologists 立陶宛泌尿科医师协会第十届三年一次会议
Pub Date : 2022-05-02 DOI: 10.15388/lietchirur.2022.21.64
N. Samalavicius
The Lithuanian Society of Coloproctologists X triennial meeting with International Conference Mayo Clinic days in Vilnius, Lithuanian–Turkish session and The International Society of University Colon and Rectal Surgeons Session. Vilnius, May 12 - 13, 2022.
立陶宛结肠直肠病学家学会X三年一次的会议,在维尔纽斯举行的梅奥诊所国际会议,立陶宛-土耳其会议和国际大学结肠和直肠外科医生学会会议。维尔纽斯,2022年5月12日至13日。
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引用次数: 0
Experimental Study of Action Different Kinetic Energy on the Colon 不同动能对结肠作用的实验研究
Pub Date : 2022-05-02 DOI: 10.15388/lietchirur.2022.21.61
Ye. A. Kvasnevskyi, M. Kashtalian, O. Gerasimenko, Oleksandr A Kvasnevskyi
The purpose of the study. To increase the effectiveness of surgical care for the wounded with combat trauma of the colon by studying of ballistic, morphological and functional features of the gunshot wounds. Patients and methods. A study of surgical treatment of 83 wounded with combat injuries of the colon, received in the area of anti-terrorist operation in the period from 2014–2018. For comparative analysis of treatment results, two clinical groups were formed: comparison and main. The comparison group included 42 wounded who were treated from April 2014 to February 2015 (the first and second periods of ATO), who used traditional surgical tactics. The main group included 41 wounded who were treated from March 2015 to 2018. Results. Analysis of the distribution of wounded with combat trauma by type of wound / injury revealed that the vast majority of them in both groups had shrapnel wounds – 49 (59.1%). There were 30 (36.1%) victims with bullet wounds, and 4 (4.8%) with closed injuries. The wounded patients with the battle trauma of the thick bowel by type of injury had missile wounds as a rule – 49 (59.1%). There were 30 (36.1%) patients with bullet wounds, and 4 (4.8%) with closed injuries. Most of the injuries were combined – 58 (69.9%), and with only abdominal injuries – 25 (30.1%), mostly multiple – 21 (25.3%). The great majority of the thick bowel injuries belonged to sigmoid – 32 (38.6%) and transverse colon – 21 (25.3%), which is explained by relatively large size of these parts of the intestine. Conclusions. The choice of surgical tactics and scope of surgical interventions on damaged organs and structures took into account the results of experimental study of mechanogenesis and pathomorphology of gunshot wounds of the colon, obtained in bench studies by modeling gunshot wounds on “thoracoabdominal ballistic material”.
研究目的。通过研究枪伤的弹道、形态和功能特点,提高结肠作战创伤伤员的外科治疗效果。患者和方法。2014年至2018年期间在反恐行动领域接受的83名结肠战斗伤伤员的外科治疗研究。为了对治疗结果进行比较分析,形成了两个临床组:对照组和主组。对照组包括2014年4月至2015年2月(ATO第一期和第二期)接受治疗的42名伤员,他们使用了传统的手术策略。主要组包括41名在2015年3月至2018年期间接受治疗的伤员。结果。按创伤/损伤类型对战斗创伤伤员分布的分析显示,两组中绝大多数伤员都有弹片伤——49人(59.1%)。有30人(36.1%)受弹伤,4人(4.8%)受闭合伤。按损伤类型划分,厚肠战斗创伤的伤员通常有49处(59.1%)导弹伤。有30名(36.1%)患者有子弹伤,4名(4.8%)患者有闭合伤。大多数损伤是合并损伤58例(69.9%),只有腹部损伤25例(30.1%),大多数是多发损伤21例(25.3%)。绝大多数厚肠损伤属于乙状结肠32例(38.6%)和横结肠21例(253%),这是因为这些部位的肠道相对较大。结论。对受损器官和结构的手术策略和手术干预范围的选择考虑了结肠枪伤机械发生和病理形态学的实验研究结果,这些实验研究是在“胸腹弹道材料”上模拟枪伤的台架研究中获得的。
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引用次数: 0
Challenges in Diagnosis and Treatment of Cushing Syndrome in Bilateral Macronodular Adrenal Hyperplasia 双侧肾上腺大结节性增生库欣综合征的诊治挑战
Pub Date : 2022-04-27 DOI: 10.15388/lietchirur.2022.21.57
Edvina Januškevičiūtė, Laura Kalakauskaitė, Ž. Visockienė
Background. Bilateral adrenal cortical hyperplasia (ACH) is one of the rare causes of adrenocorticotropic hormone (ACTH)-independent Cushing’s syndrome (CS), where lateralization of cortisol secretion and choice of treatment techniques are challenging. Percutaneous radiofrequency ablation (RFA) is a safe and effective minimally invasive treatment for benign and malignant tumors, but it is not commonly used to treat CS in bilateral ACH. Case description. A 79-year-old patient developed ACTH-independent CS with bilateral ACH. Adrenal venous sampling (AVS) showed right sided cortisol hypersecretion. Due to serious comorbidities it was decided to perform percutaneus RFA. The procedure was successful and without any complications. Hydrocortisone replacement therapy was given to ma­nage adrenal insufficiency after the procedure. Conclusions. Percutaneous RFA is an effective minimally invasive procedure for the treatment of cortisol producing adrenal tumors. Reduction of symptoms caused by the disease has been observed after the procedure. It is also expected that hormone deficiency developed after the procedure will be transient.
背景双侧肾上腺皮质增生(ACH)是促肾上腺皮质激素(ACTH)非依赖性库欣综合征(CS)的罕见原因之一,皮质醇分泌的侧化和治疗技术的选择具有挑战性。经皮射频消融术(RFA)是一种安全有效的良恶性肿瘤微创治疗方法,但在治疗双侧ACH的CS中并不常用。案例描述。一名79岁的患者发展为ACTH非依赖性CS伴双侧ACH。肾上腺静脉取样(AVS)显示右侧皮质醇分泌过多。由于严重的合并症,决定进行经皮射频消融。手术成功,没有任何并发症。术后应用氢化可的松替代治疗肾上腺功能不全。结论。经皮RFA是一种有效的微创手术,用于治疗产生皮质醇的肾上腺肿瘤。手术后观察到由该疾病引起的症状减轻。手术后出现的激素缺乏也是暂时性的。
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引用次数: 0
Biliary Ascariasis: Case Report 胆道蛔虫病1例报告
Pub Date : 2022-04-27 DOI: 10.15388/lietchirur.2022.21.59
Rūta Aliulytė, Agnė Kavaliauskaitė, D. Venskutonis
Biliary ascariasis is a pathology caused by roundworms when parasites migrate from the jejunum into the bile ducts manifes­ting in typical clinical symptoms. Ascaris’ eggs mature in the soil, because of that ascariasis is mostly prevalent in tropical and subtropical regions due to poor hygiene, lack of clean drinking water, the consumption of contaminated food. Diagnosis of biliary ascariasis consists of blood and faecal examination, imaging tests, such as ultrasound, magnetic resonance imaging and endoscopic retrograde cholangio­graphy. In this article, we present the case of a patient with biliary ascariasis, review of the epidemiology, life cycle, causes of the migration into the bile duct, clinical manifestations, diagnostic methods and treatment options.
胆道蛔虫病是由蛔虫引起的一种病理学,寄生虫从空肠迁移到胆管,表现出典型的临床症状。蛔虫卵在土壤中成熟,由于卫生条件差、缺乏清洁饮用水、食用受污染的食物,蛔虫病大多在热带和亚热带地区流行。胆道蛔虫症的诊断包括血液和粪便检查、超声、磁共振成像和内镜逆行胆管造影等影像学检查。在这篇文章中,我们介绍了一例胆道蛔虫症患者,回顾了流行病学、生命周期、迁移到胆管的原因、临床表现、诊断方法和治疗方案。
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引用次数: 0
Laparoscopically Treated Giant Gastric Bezoar Complicated with Large Ulcer in Young Patient 腹腔镜治疗青年巨大胃牛黄并发大溃疡
Pub Date : 2021-12-30 DOI: 10.15388/lietchirur.2021.20.49
Cemal Ulusoy, A. Nikolovski, Giray Yavuz, Tuba Saydam, Ali İlbey
Gastric bezoars are rare but well known intraluminal formations in the gastrointestinal system. Reports for gastric bezoar treatment include dissolution, endoscopic retrieval and surgery (open and laparoscopic). We are presenting a case of 32 years old male patient presented with giant gastric bezoar complicated with large ulcer. The patient was operated laparoscopically with success. Laparoscopic surgery is safe alternative to open surgery for giant gastric bezoars treatment.
胃结石是胃肠系统中罕见但众所周知的管腔内形成物。胃牛黄治疗的报告包括溶解、内镜下取出和手术(开放式和腹腔镜)。我们报告一例32岁男性患者,表现为巨大胃牛黄并发大溃疡。这个病人用腹腔镜手术成功了。腹腔镜手术是治疗巨大胃结石的安全替代开放手术。
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引用次数: 0
Welcoming the Centenary of the University of Lithuania in Kaunas: Higher Courses, the Beginning of the Development of Academic Surgery, it’s First Heads 在考纳斯迎接立陶宛大学成立一百周年:高等课程,学术外科发展的开端,它的第一任校长
Pub Date : 2021-12-30 DOI: 10.15388/lietchirur.2021.20.46
Ž. Saladžinskas
The origins of higher education in Kaunas began in 1919, during a difficult period for the country, during the struggle for its independence. The young state of Lithuania laid the first foundations of higher education and sought to restore the health care system. The article presents a brief history of the establishment of a higher school in Kaunas, the establishment of higher medical courses and a university. One of the initiators of this work, along with other prominent Lithuanians, was the famous surgeon and public figure at the time Juozas Žemgulys. The emergence of the first departments of surgery at the then University of Lithuania in Kaunas and the beginning of their work is reviewed, the first supervisors Janis Dzirne, Hans Boit, Aleksandr Hagentorn are presented. They significantly contributed to the development of surgery in the country, helped to grow a new generation of Lithuanian surgeons.
考纳斯高等教育的起源始于1919年,当时该国正处于独立斗争的艰难时期。年轻的立陶宛奠定了高等教育的第一个基础,并试图恢复医疗保健系统。本文简要介绍了考纳斯建立高等学校、建立高等医学课程和大学的历史。这项工作的发起人之一,以及其他著名的立陶宛人,是当时著名的外科医生和公众人物Juozasžemgulys。回顾了当时位于考纳斯的立陶宛大学第一批外科的出现及其工作的开始,介绍了第一批导师Janis Dzirne、Hans Boit、Aleksandr Hagenton。他们为立陶宛外科的发展做出了重大贡献,帮助培养了新一代立陶宛外科医生。
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引用次数: 0
Influence of Educational Methods on Bowel Preparation for Coloncopy: Systematic Literature Review 教育方法对结肠镜检查肠道准备的影响:系统文献综述
Pub Date : 2021-12-30 DOI: 10.15388/lietchirur.2021.20.47
E. Kildušis, G. Brimas
 Background. To review and evaluate the influence of bowel preparation educational methods for colonoscopy used in world practice. Research material and methods. Scientific publications have been searched in PubMed, Cochrane Libraly, Google Scholar and SpringerLink databases since 2011 January 1 until 2020 May 10. The following keywords were used in the search: improving bowel preparation, cleansing, colonoscopy, education, enhanced, method, instruction, intervention, comparison, validated bowel preparation scale, adult participants. The specified inclusion and exclusion criteria were used in the selection of articles, and a detailed analysis of educational methods was performed. Results. This systematic review includes 21 articles, which assesses the various ways in which patients are educated before colonoscopy. The publications are divided into 3 groups: (1) patients in the study group educated in some way are compared with those in the control group who received standard instructions; (2) all patients received standard instructions, and the patients in the study group were additionally educated in some way and compared with the control group; (3) all patients received standard instructions, and patients in the study groups (there was more than one study group) were additionally educated in some way and the study groups were compared with each other. The main comparative results of the used bowel preparation for colonoscopy educational methods are presented. Conclusion. It is necessary to objectively (quantitatively, using standardized scales) evaluate the effectiveness of emerging patient bowel preparation before colonoscopy educational methods, to standardize patient training (education) protocols, so that it is possible to properly compare different forms of education.
背景回顾和评估结肠镜检查肠道准备教育方法在世界实践中的影响。研究材料和方法。自2011年1月1日至2020年5月10日,科学出版物已在PubMed、Cochrane Libraly、Google Scholar和SpringerLink数据库中搜索。搜索中使用了以下关键词:改善肠道准备、清洁、结肠镜检查、教育、强化、方法、指导、干预、比较、验证的肠道准备量表、成年参与者。在文章的选择中使用了特定的纳入和排除标准,并对教育方法进行了详细分析。结果。这篇系统综述包括21篇文章,评估了结肠镜检查前对患者进行教育的各种方式。将出版物分为3组:(1)将研究组中接受某种教育的患者与对照组中接受标准指导的患者进行比较;(2) 所有患者都接受了标准的指导,研究组的患者在某种程度上接受了额外的教育,并与对照组进行了比较;(3) 所有患者都接受了标准的指导,研究组(不止一个研究组)的患者接受了某种方式的额外教育,并对研究组进行了比较。介绍了用于结肠镜检查教育方法的肠道准备的主要比较结果。结论。有必要客观(定量,使用标准化量表)评估结肠镜检查前新出现的患者肠道准备的有效性教育方法,规范患者培训(教育)方案,以便能够适当比较不同形式的教育。
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引用次数: 0
Protocol of Spinal Deformity Surgery and Anaesthesia in Children and Adult: Recommended Preoperative and Perioperative Diagnostic and Treatment Algorithm in Spinal Deformity Surgery 儿童和成人脊柱畸形手术和麻醉方案:脊柱畸形手术的术前和围手术期诊断和治疗算法
Pub Date : 2021-12-30 DOI: 10.15388/lietchirur.2021.20.48
Lukas Šalaševičius, Nijolė Savičienė, Rasa Alsytė, D. Gasiūnaitė, Giedrius Bernotavičius, O. Lapteva, K. Saniukas, Arūnas Vaitkevičius, R. Kvaščevičius, Vidūnas Daugelavičius, J. Šipylaitė, S. Ročka
Spinal deformity surgery is one of the most challenging surgeries that is only performed by highly professional multidisciplinary team in dedicated spinal centres. In the paper, the authors share and present the algorithm for safe and successful management of complex spinal disorders in Vilnius University Hospital Santaros Clinics.
脊柱畸形手术是最具挑战性的手术之一,只有在专门的脊柱中心由高度专业的多学科团队进行。在这篇论文中,作者分享并介绍了维尔纽斯大学医院Santaros诊所安全成功治疗复杂脊柱疾病的算法。
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引用次数: 0
Computed Tomography-Guided Percutaneous Lung Biopsy Complicated by Symptomatic Systemic Air Embolism: Case Report and Review of the Literature 计算机断层扫描引导下经皮肺活检并发症状性系统性空气栓塞的病例报告及文献复习
Pub Date : 2021-12-30 DOI: 10.15388/lietchirur.2021.20.50
G. Ledas, D. Jocius, Juozas Jarašūnas, Žymantas Jagelavičius
Computed tomography-guided percutaneous core needle biopsy of the lung is an undoubtedly useful and well-established interventional radiological procedure for the diagnosis of indeterminate pulmonary lesions. Complications of percutaneous core needle biopsy, such as pneumothorax and hemoptysis are considered mild and self-resolving, however systemic air embolism is considered a potentially fatal complication. Systemic air embolism occurs when the air enters a pulmonary vein secondary to a percutaneous CT-guided lung biopsy and is expelled into systemic circulation. Systemic air embolism is extremely rare: incidence of clinically apparent SAE is estimated at 0.061–0.17%, while clinically silent systemic air embolism may be as high as 3.8–4.8%. This study reports a case of air embolism in the cerebral arteries that resulted from a complex CT-guided percutaneous core needle biopsy of the lung. The present case highlights the main mechanisms of this pathology, risk factors, importance of complete thoracic CT after procedure, as well as management of rare complications.
计算机断层扫描引导下经皮肺穿刺活检无疑是一种有用且成熟的介入放射学程序,可用于诊断不确定的肺部病变。经皮穿刺核心针活检的并发症,如肺气肿和咳血,被认为是轻微的,可以自行解决,但全身性空气栓塞被认为是一种潜在的致命并发症。当空气进入经皮CT引导的肺活检后的肺静脉并排出到系统循环中时,就会发生系统性空气栓塞。全身性空气栓塞极为罕见:临床上明显的SAE发生率估计为0.061–0.17%,而临床上无症状的全身性空气血栓可能高达3.8–4.8%。本研究报告了一例脑动脉中的空气栓塞,由复杂的CT引导下经皮肺穿刺活检引起。本病例强调了这种病理的主要机制、危险因素、手术后完整胸部CT的重要性以及罕见并发症的处理。
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引用次数: 0
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Lietuvos Chirurgija
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