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IMPACT OF OBESITY IN CHILDREN WITH ACQUIRED PNEUMONIA FROM THE COMMUNITY 肥胖对社区获得性肺炎儿童的影响
Pub Date : 2018-12-30 DOI: 10.18004/IMT/201813210-20
N. González, Sara Amarilla, C. Zárate, D. Lovera, Silvio Apodaca, A. Arbo
Goals. To evaluate the impact of Obesity on Community Acquired Pneumonia (CAP) in the pediatric population that has passed the breastfeeding period. Population and methods. Study carried out in the Institute of Tropical Medicine (IMT) of Paraguay in which the cases with NAC in children and adolescents between 2 and 15 years, hospitalized between 2009 and 2013, will be analyzed. The diagnosis of NAC was based on the presence of Febrile respiratory symptomatology and condensation image in the thorax Rx. In each case the presence of fever, tachypnea, runs, chest pain, oxygen saturation (SatO2), laboratorial data (leukocytocyte and platelet count, hemoglobin, liver function), presence of pleural effusion, oxygen requirement (O2) are evaluated. supplementary, need for admission to intensive care unit (ICU), need for mechanical ventilation (ARM), days of hospitalization, and mortality. The weight in kilograms and the height in centimeters were measured. The body mass index was calculated with the formula of BMI = Weight / Size2. The nutritional status is based on the age and agreement of the charts of the World Health Organization (WHO) and the National Center for Health Statistics (NCHS) of the United States (year 2006). The groups of obese and eutrophic patients were compared. Results We analyzed 231 patients between 2 and 15 years old, of which 143 (62%) corresponded to children from 2 to 5 years old and 88 (38%) from 5 to 15 years old. Forty (17%) were obese and 160 (70%) were eutrophic. No difference was found in the presentation of fever (p = 0.9), runs (p = 0.06), chest pain (p = 1). Tachypnea showed a difference in favor of eutrophics (p <0.01). SatO2 <94% in the obese was higher (p <0.05). Regarding the labor data, the GPT values were higher in the obese patients (p <0.05) and the eutrophic ones are published more frequently in the pleural frame (p <0.01). No differences were found in the frequency of use of oxygen therapy (p = 0.7), admission to the ICU (p = 0.3), need for ARM (p = 1) and in the days of hospitalization between both groups. Similarly, there was no difference in mortality: 0/40 vs 4/160 (p = 0.58). Conclusion. The prevalence of obesity is higher than in official records. The clinical presentation and evolution of CAP in obese patients was not found to differ significantly from what is observed in eutrophic patients. However, obese patients with CAP have lower values of SatO2 on admission than eutrophic patients, as an expression of lower gas exchange. In addition, obesity has not been associated with differences in the leukocyte response and Hb levels compared with eutrophic patients, although it has been found higher values of GPT, probably related to liver involvement in obesity. Finally, the Diciembre 2018 Rev. Inst. Med. Trop 2018;13(2)10-21 10.18004/imt/201813210-21 12 length of hospital stay, the frequency of admission to the ICU and mortality were similar in both groups
的目标。评估肥胖对已过母乳喂养期的儿科人群社区获得性肺炎(CAP)的影响。人口和方法。在巴拉圭热带医学研究所进行的一项研究中,将分析2009年至2013年住院治疗的2至15岁儿童和青少年NAC病例。NAC的诊断是基于发热呼吸症状和胸腔冷凝图像的存在。在每个病例中,评估发热、呼吸急促、跑步、胸痛、氧饱和度(SatO2)、实验室数据(白细胞和血小板计数、血红蛋白、肝功能)、胸腔积液的存在、氧气需求(O2)。补充,需要入住重症监护病房(ICU),需要机械通气(ARM),住院天数和死亡率。测量了体重(公斤)和身高(厘米)。体重指数的计算公式为BMI = Weight / Size2。营养状况是根据世界卫生组织(世卫组织)和美国国家卫生统计中心(国家卫生统计中心)(2006年)的年龄和一致性图表编制的。比较肥胖组和富营养化组。结果我们分析了231例2 ~ 15岁的患者,其中143例(62%)对应于2 ~ 5岁儿童,88例(38%)对应于5 ~ 15岁儿童。肥胖40只(17%),富营养化160只(70%)。发热(p = 0.9)、跑动(p = 0.06)、胸痛(p = 1)的表现无差异。呼吸急促有利于富营养化(p <0.01)。肥胖组SatO2 <94%较高(p <0.05)。在分娩资料中,肥胖患者GPT值较高(p <0.05),富营养化患者在胸膜框架中出现频率较高(p <0.01)。两组患者氧疗频次(p = 0.7)、ICU入院次数(p = 0.3)、ARM用药次数(p = 1)、住院天数均无统计学差异。同样,死亡率也没有差异:0/40 vs 4/160 (p = 0.58)。结论。肥胖的流行率高于官方记录。肥胖患者CAP的临床表现和演变与富营养化患者没有明显差异。然而,肥胖CAP患者入院时的SatO2值低于富营养化患者,这是气体交换较低的表现。此外,与富营养化患者相比,肥胖与白细胞反应和Hb水平的差异没有关联,尽管已经发现GPT值较高,可能与肥胖的肝脏受累有关。最后,Diciembre 2018 Rev. Inst. Med. Trop 2018;13(2)10-21 10.18004/imt/201813210-21 12两组住院时间、ICU入院次数和死亡率相似
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引用次数: 0
CLINICAL AND EPIDEMIOLOGICAL CHARACTERISTICS OF THE OPHIDIC ACCIDENTS OF A REGIONAL HOSPITAL OF PARAGUAY, 2010 TO 2016 2010年至2016年巴拉圭一家地区医院眼科事故的临床和流行病学特征
Pub Date : 2018-12-30 DOI: 10.18004/imt/201813221-30
María Belén Vera-Sanabria, C. Rios-González
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引用次数: 0
PATIENT WITH HIV AND CO-INFECTED BY HPV: A CASE STUDY HIV和HPV共同感染者的病例研究
Pub Date : 2018-12-30 DOI: 10.18004/IMT/201813239-44
Máyda Pereira Vilela-Ferreira, Raphael Oliveira Ramos-Franco-Netto, Juliana de Almeida-Rodrigues Franco-Netto, J. González-Escobar, Berenice Moreira, Marcos Arturo Ferreira-Aguero
Currently, infections caused by HIV and HPV are considered a major public health problem worldwide. The objective was to analyze the impact of HIV and HPV on family, sexual and social life; To identify the diagnoses and to relate the viral and CD4 load and to evaluate the adherence to ART. A 52-year-old man with a diagnosis of HIV and HPV was able to identify the main multidisciplinary diagnoses according to NANDA, with a total of 11 diagnoses. It is suggested a more reflective look by the physician and his multidisciplinary team regarding public health, since it is not enough to treat the infected patient, it is necessary that the patient receive guidance about the health-disease process of the HIV patient with co-infection by the HPV in order to promote secondary prevention
目前,由艾滋病毒和人乳头瘤病毒引起的感染被认为是世界范围内的一个主要公共卫生问题。目的是分析HIV和HPV对家庭、性和社会生活的影响;确定诊断,并将病毒和CD4载量联系起来,评估抗逆转录病毒治疗的依从性。根据NANDA,一名诊断为HIV和HPV的52岁男性能够确定主要的多学科诊断,总共有11种诊断。建议医生和他的多学科团队对公共卫生有更多的反思,因为仅仅治疗感染患者是不够的,有必要对患者进行指导,了解合并感染HPV的HIV患者的健康-疾病过程,以促进二级预防
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引用次数: 0
Incidence of Non Prescribed Use of Methylphenidate among Medical Students 医学生非处方使用哌甲酯的发生率
Pub Date : 2018-06-30 DOI: 10.18004/imt/201813117-23
Raphael Oliveira Ramos Franco Netto, Juliana de Almeida Rodrigues Franco Netto, N. Z. S. Junior, Sandra Silva, Marcos Arturo Ferreira-Aguero, Balbina Coronel-de Bobadilla, Angel Pifferrer
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引用次数: 1
Knowledge, attitudes and practices on medical students in Mayaro virus, 2017 2017年医学生对Mayaro病毒的认识、态度和做法
Pub Date : 2018-06-30 DOI: 10.18004/IMT/201813132-39
C. Rios-González, Ginno Alessandro De Benedictis-Serrano, Alfonzo David Chirino Caicedo
Introduction: In Latin America there are several arboviruses that affect populations and present similar symptoms, such as the Mayaro virus, which has not been studied extensively on the continent, having a high capacity to spread Objective: to determine the knowledge, attitudes and practices about the Mayaro in medical students from Latin America during the months of July to August 2017. Junio 2018 Rev. Inst. Med. Trop 2018;13(1)32-39 10.18004/imt/201813132-39 Material and methods: A cross-sectional, observational, cross-sectional, non-probabilistic study was conducted for convenience in medical students. Results: A total of 989 medical students aged 18-32 years were included in the study, of whom 58.24% (576) were male, were third year 33.47 (331), and 44, 08% of the participants were from Venezuela (446). The level of knowledge was 71.39% (706) low, 24.97% (247) considered that the public has the most important role in the control of Mayaro, and 39.23% (388) do not use repellents. Conclusion: The level of general knowledge was low, indecisive / doubtful attitudes and appropriate practices.
在拉丁美洲,有几种虫媒病毒影响人群并呈现类似症状,例如Mayaro病毒,该病毒尚未在该大陆进行广泛研究,具有很高的传播能力。目的:确定2017年7月至8月期间拉丁美洲医学生对Mayaro病毒的知识、态度和做法。材料与方法:为方便起见,对医学生进行横断面、观察性、横断面、非概率研究。结果:共纳入989名年龄在18-32岁的医学生,其中58.24%(576人)为男性,大三33.47%(331人)为男性,44.08%的参与者来自委内瑞拉(446人)。71.39%(706人)的调查对象对驱蚊剂的了解程度较低,24.97%(247人)的调查对象认为公众对防蚊剂的作用最大,39.23%(388人)的调查对象不使用驱蚊剂。结论:一般知识水平低,优柔寡断/怀疑态度和适当的做法。
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引用次数: 0
Impact of Pneumonias Associated with Mechanical Ventilation in Mortality in an Adult Intensive Care Unit 机械通气相关肺炎对成人重症监护病房死亡率的影响
Pub Date : 2018-06-30 DOI: 10.18004/IMT/201813124-31
Zunilda Garay, A. Vera, Nora Pitta, H. Bianco, C. Ayala, P. Almada, C. M. Cuellar
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引用次数: 1
Epidemiology, clinical and prognostic factors of Invasive Meningococcal Disease in a reference center in Paraguay. 2005 to 2018 巴拉圭某参考中心侵袭性脑膜炎球菌病流行病学、临床及预后因素分析。2005 - 2018
Pub Date : 2018-06-30 DOI: 10.18004/IMT/201813140-53
Sara Amarilla, D. Lovera, C. M. Cuellar, S. Araya, C. Aranda, Gustavo Chamorro, A. Kawabata, O. Merlo, A. Arbo
Introduction: Meningococcal disease has been and continues to be an important cause of morbidity and mortality around the world. Objectives: To analyze the clinical and epidemiological characteristics of patients with invasive meningococcal infection hospitalized in a reference hospital center. Materials and methods: A descriptive, observational and retrospective study based in the review of clinical records of patients admitted between 2005 and 2018 in the Institute of Tropical Medicine in whom Neisseria meningitidis was isolated o detected by PCR in blood or CSF. Results: Forty-four patients with invasive meningococcal disease were recruited during the period studied (3 ± 2 cases/year). The cases predominated in the age group <5 years (36% of all cases), with similar gender distribution. Forty-six patients (59%) had meningitis and 18 (41%) meningococcemia, 12 of them (27%) with concomitant meningitis. Forty-three percent of the patients required admission to the ICU. The lethality was 20.5% (9/44), higher in patients with meningococcemia, although without statistical significance (p = 0.16). The presence of shock (p<0.01), the ICU requirement (p=0.001), leukopenia <5000, leukocytes/mm3 (p <0.01), leukocytosis>15000/mm3 (p=0.03), thrombocytopenia<150000/mm3 (p=0.01) and the presence of <100 leukocytes field in CSF (p = 0.02) were factors associated with higher mortality. No association was found between severity and serotypes. When all the years of the study was analyzed, serogroup B was the predominant (50%); however, in the last 3 years all isolates (n = 14) corresponded to serogroups C (n = 10, 71%) and W135 (n = 4, 29%). Conclusion: Meningococcal disease presents a stable pattern of endemicity in Paraguay, with a recent increase in cases of serogroup C and W135 Currently the serogroup C constitues more than 70% of the cases. The presence of shock, leukocytosis>15,000/mm3, leukopenia <5000 / mm3, and thrombocytopenia were associated with increased mortality.
脑膜炎球菌病一直是并将继续是世界各地发病率和死亡率的一个重要原因。目的:分析某参比医院中心侵袭性脑膜炎球菌感染患者的临床及流行病学特征。材料和方法:一项描述性、观察性和回顾性研究,基于对热带医学研究所2005年至2018年间入院的患者的临床记录的回顾,这些患者在血液或脑脊液中分离到脑膜炎奈瑟菌或通过PCR检测。结果:研究期间共纳入44例侵袭性脑膜炎球菌病患者(3±2例/年)。病例主要发生在15000/mm3 (p=0.03)、血小板减少15000/mm3、白细胞减少<5000 /mm3和血小板减少与死亡率增加相关的年龄组。
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引用次数: 1
Characterization of the accidents of biological risk and use of prophylaxis in health workers by occupational exposure, that consulted in the National Program of Fight against AIDS from January to December of the year 2013 2013年1月至12月在《国家防治艾滋病方案》中咨询的关于卫生工作者因职业接触而发生的生物风险事故和预防措施使用情况的描述
Pub Date : 2018-06-30 DOI: 10.18004/IMT/20181314-16
L. Flores, D. Narváez, A. Armoa
One of the routes of transmission of the HIV virus is blood through sharps accidents; health workers who are exposed to needle stick injuries that contain HIV-infected blood have a 0.23% risk of being infected. The objective of this study is to characterize the biological hazard accidents and the use of occupational post-exposure prophylaxis in health workers, who consulted in the National Program to Fight AIDS from January to December 2013. Material and Method: Observational, descriptive, cross-sectional design. 66 tokens were included for this study. The variables analyzed were: age, sex, origin, occupation or workplace, time of accident, occupational exposure, health worker, source patient, type of work accident or accident classification according to risk, type of exposure, indication of postprophylaxis exposure, side effects of antiretroviral drugs. Results: 85% were women and 15% were men. The mean age was 33.1 ± 8.9 (20-62) years. Health Workers more exposed were the nursing staff in 36.6%; followed by cleaners 24.24%, and medical personnel 18.8%. The accident was classified as mild in 62.1% and as severe in 37.8%. The type of exposure, in 65.1% was type 1 (punctures, cut with needles grooved or hollow, scalpel), the patient source was known in 54.5% of cases. Among the known source patients, 62% with serology positive for HIV, 77% started Prophylaxis Post Exposure. Only 6% completed the treatment schedule. Among those who completed PPE, one of them presented side effects (dizziness, nausea and facial erythema). Conclusion: Universal precaution is the first line of defense to prevent occupational exposure. Assuming that all patients are potentially infected is the only way to optimize measures to prevent the transmission of this pathology, with assurance of controls and measures to complete prophylaxis if necessary.
艾滋病病毒的传播途径之一是血液通过尖锐事故传播;暴露在含有HIV感染血液的针扎伤中的卫生工作者被感染的风险为0.23%。本研究的目的是描述2013年1月至12月在国家抗击艾滋病计划中咨询的卫生工作者的生物危害事故和职业暴露后预防的使用情况。材料和方法:观察性、描述性、横断面设计。本研究共纳入66个代币。分析的变量为:年龄、性别、出身、职业或工作场所、事故时间、职业暴露、卫生工作者、来源患者、根据风险划分的工作事故类型或事故分类、暴露类型、运动后暴露指征、抗逆转录病毒药物副作用。结果:85%为女性,15%为男性。平均年龄为33.1±8.9(20-62)岁。卫生工作者接触较多的是护理人员,占36.6%;其次是清洁工24.24%,医务人员18.8%。事故分为轻度(62.1%)和重度(37.8%)。暴露类型为1型(穿孔、用带凹槽或空心的针头切割、手术刀)的占65.1%,54.5%的病例已知患者来源。在已知来源的患者中,62%的HIV血清学阳性,77%的患者在接触后开始预防。只有6%的患者完成了治疗计划。在完成PPE的患者中,其中一人出现了副作用(头晕、恶心和面部红斑)。结论:普遍预防是预防职业接触的第一道防线。假设所有患者都有潜在感染,这是优化措施以防止这种病理学传播的唯一方法,并在必要时确保控制和措施以完成预防。
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引用次数: 0
Ventilator-associated pneumonia: a problem of intensive care units 呼吸机相关性肺炎:重症监护室的一个问题
Pub Date : 2018-06-30 DOI: 10.18004/IMT/20181311-3
A. Arbo
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引用次数: 0
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Revista del Instituto de Medicina Tropical
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