首页 > 最新文献

Indian Journal of Allergy Asthma and Immunology最新文献

英文 中文
Recommendations for allergy practice during COVID-19 pandemic in India 印度COVID-19大流行期间过敏实践建议
Pub Date : 2020-01-01 DOI: 10.4103/ijaai.ijaai_28_20
M. Agarwal, A. Singh, S. Gaur, P. Kathuria, V. Jain, M. Goyal, K. Nagendra Prasad
We are living in an unprecedented difficult time due to the infectious COVID-19 pandemic, a global emergency. During the on-going pandemic, most allergy/immunology care could be postponed/delayed or handled through virtual care. Seven experts from different parts of India deliberated on this subject in 3 weekly webinars (May 10, 17, and 24, 2020) charted out consensus-based approach for diagnosis and management of patients suffering with allergic respiratory diseases in India during this COVID-19 pandemic. This publication includes these recommendations.
我们正生活在一个前所未有的困难时期,因为传染性COVID-19大流行是一种全球紧急情况。在目前的大流行期间,大多数过敏/免疫学护理可以推迟/延迟或通过虚拟护理处理。来自印度不同地区的七名专家在三次每周网络研讨会(2020年5月10日、17日和24日)上讨论了这一主题,制定了基于共识的方法,用于在2019冠状病毒病大流行期间诊断和管理印度患有过敏性呼吸道疾病的患者。本出版物包括这些建议。
{"title":"Recommendations for allergy practice during COVID-19 pandemic in India","authors":"M. Agarwal, A. Singh, S. Gaur, P. Kathuria, V. Jain, M. Goyal, K. Nagendra Prasad","doi":"10.4103/ijaai.ijaai_28_20","DOIUrl":"https://doi.org/10.4103/ijaai.ijaai_28_20","url":null,"abstract":"We are living in an unprecedented difficult time due to the infectious COVID-19 pandemic, a global emergency. During the on-going pandemic, most allergy/immunology care could be postponed/delayed or handled through virtual care. Seven experts from different parts of India deliberated on this subject in 3 weekly webinars (May 10, 17, and 24, 2020) charted out consensus-based approach for diagnosis and management of patients suffering with allergic respiratory diseases in India during this COVID-19 pandemic. This publication includes these recommendations.","PeriodicalId":53075,"journal":{"name":"Indian Journal of Allergy Asthma and Immunology","volume":"58 1","pages":"5 - 7"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82898468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A study of various investigative modalities in establishing the cause of chronic urticaria 建立慢性荨麻疹病因的各种调查方式的研究
Pub Date : 2019-07-01 DOI: 10.4103/ijaai.ijaai_28_18
N. Naseerudeen, Sandeep Khuraiya, V. Jain, R. Khullar, D. Kachhawa
INTRODUCTION: Urticaria is a transient eruption of erythematous or edematous swellings of the dermis and is usually associated with itching. Angioedema consists of transient swellings in the deeper dermal, subcutaneous, and submucosal tissues. Urticaria and angioedema occur as clinical manifestations of various immunological and inflammatory mechanisms, or they may be idiopathic. MATERIALS AND METHODS: The study included 500 patients of chronic urticaria who were recruited from the outpatient department. The detailed history, cutaneous, and systemic examination was done. All patients should be subjected to a complete blood count, absolute eosinophil count, ESR, urine analysis, stool examination, liver function test, blood sugar, and renal function test. In the patients where history will be suggestive of any specific disease, screening for hepatitis B and C, antinuclear antibody test, and rheumatoid factor. Autologous serum skin test (ASST) will be performed in all the patients with chronic urticaria. RESULTS: Out of 500 patients, 211 were female and 289 were male. Most common age group was 21–40 years (58%). Most cases (60%) of chronic urticaria were of 2–6 months duration. Most patients (47%) were worse in the evening and night time. A personal history of atopy was present in 6.6% patients. A total of 38 (7.6%) had chronic urticaria with evidence of a focus of infection. In the present study, food items were observed to be aggravating chronic urticaria in 10 (2%) patients. 19 patients of chronic urticaria were found to have concomitant systemic disease, which included 16 with thyroid disease and 3 with rheumatoid arthritis. ASST was found to be positive in 172 patients with raised serum IgE levels in 120 patients. CONCLUSION: The present study demonstrates that an extended diagnostic workup may be helpful in patients with chronic urticaria in addition to thorough history taking and physical examination for proper treatment.
简介:荨麻疹是一种短暂的真皮红斑或水肿性肿胀,通常伴有瘙痒。血管性水肿由皮肤深层、皮下和粘膜下组织的短暂性肿胀组成。荨麻疹和血管性水肿是多种免疫和炎症机制的临床表现,也可能是特发性的。材料和方法:该研究包括500名从门诊招募的慢性荨麻疹患者。做了详细的病史、皮肤和全身检查。所有患者均应进行全血细胞计数、绝对嗜酸性粒细胞计数、ESR、尿液分析、粪便检查、肝功能检查、血糖和肾功能检查。病史提示有任何特殊疾病的患者,应进行乙型和丙型肝炎筛查、抗核抗体试验和类风湿因子检测。所有慢性荨麻疹患者均行自体血清皮肤试验(自体血清皮肤试验)。结果:500例患者中,女性211例,男性289例。最常见的年龄组为21-40岁(58%)。大多数(60%)慢性荨麻疹的病程为2-6个月。大多数患者(47%)在傍晚和夜间加重。6.6%的患者有个人特应性病史。共有38例(7.6%)患有慢性荨麻疹,有感染灶的证据。在本研究中,观察到10例(2%)患者的食物会加重慢性荨麻疹。19例慢性荨麻疹患者并发全身性疾病,其中甲状腺疾病16例,类风湿性关节炎3例。172例血清IgE水平升高,120例血清IgE水平升高。结论:本研究表明,除了全面的病史和体格检查外,长期的诊断检查可能对慢性荨麻疹患者有帮助。
{"title":"A study of various investigative modalities in establishing the cause of chronic urticaria","authors":"N. Naseerudeen, Sandeep Khuraiya, V. Jain, R. Khullar, D. Kachhawa","doi":"10.4103/ijaai.ijaai_28_18","DOIUrl":"https://doi.org/10.4103/ijaai.ijaai_28_18","url":null,"abstract":"INTRODUCTION: Urticaria is a transient eruption of erythematous or edematous swellings of the dermis and is usually associated with itching. Angioedema consists of transient swellings in the deeper dermal, subcutaneous, and submucosal tissues. Urticaria and angioedema occur as clinical manifestations of various immunological and inflammatory mechanisms, or they may be idiopathic. MATERIALS AND METHODS: The study included 500 patients of chronic urticaria who were recruited from the outpatient department. The detailed history, cutaneous, and systemic examination was done. All patients should be subjected to a complete blood count, absolute eosinophil count, ESR, urine analysis, stool examination, liver function test, blood sugar, and renal function test. In the patients where history will be suggestive of any specific disease, screening for hepatitis B and C, antinuclear antibody test, and rheumatoid factor. Autologous serum skin test (ASST) will be performed in all the patients with chronic urticaria. RESULTS: Out of 500 patients, 211 were female and 289 were male. Most common age group was 21–40 years (58%). Most cases (60%) of chronic urticaria were of 2–6 months duration. Most patients (47%) were worse in the evening and night time. A personal history of atopy was present in 6.6% patients. A total of 38 (7.6%) had chronic urticaria with evidence of a focus of infection. In the present study, food items were observed to be aggravating chronic urticaria in 10 (2%) patients. 19 patients of chronic urticaria were found to have concomitant systemic disease, which included 16 with thyroid disease and 3 with rheumatoid arthritis. ASST was found to be positive in 172 patients with raised serum IgE levels in 120 patients. CONCLUSION: The present study demonstrates that an extended diagnostic workup may be helpful in patients with chronic urticaria in addition to thorough history taking and physical examination for proper treatment.","PeriodicalId":53075,"journal":{"name":"Indian Journal of Allergy Asthma and Immunology","volume":"65 1","pages":"98 - 104"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86511375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Allergic bronchopulmonary aspergillosis: Indian scenario 过敏性支气管肺曲菌病:印度情况
Pub Date : 2019-07-01 DOI: 10.4103/ijaai.ijaai_37_19
R. Prasad, R. Kacker, N. Gupta
Aspergillus is ubiquitous, occurring in mycelial form and grows at 15-530C and humid conditions. Pulmonary aspergillosis is a clinical spectrum of lung disease caused by the fungus Aspergillus. ABPA is the commonest disease among allergic bronchopulmonary mycoses. The exact prevalence of ABPA is not known but contemporary estimates suggested that ABPA complicates 1 to 11% of all chronic cases of bronchial asthma. The basic underlying immuno-pathophysiologic process in ABPA is a hypersensitivity reaction to fungus in the bronchial tree. Patients are usually atopic with previous history of bronchial asthma. The onset is insidious with constitutional symptoms like anorexia, fatigue, weight loss, headache, generalized aches and pains, and low-grade fever. It is characterized by repeated episodes of exacerbation with periods of remission, if untreated may progress to fibrotic lung disease. Patients with chronic fibrotic disease may present with cyanosis, corpulmonale and respiratory failure. Radiologically fleeting shadows are characteristic of ABPA. Bronchiectasis, centrilobular nodules and mucoid impaction are main features of ABPA seen in CT scan thorax. Oral corticosteroid remains the cornerstone for the treatment of ABPA. Optimization of baseline asthma therapy is essential. Early diagnosis and proper treatment may alter the prognosis of disease and further prevent end stage lung fibrosis.
曲霉无处不在,以菌丝形式出现,生长在15-530C和潮湿的条件下。肺曲霉病是由真菌曲霉引起的一种临床肺部疾病。ABPA是过敏性支气管肺真菌病中最常见的疾病。ABPA的确切患病率尚不清楚,但目前的估计表明,在所有慢性支气管哮喘病例中,ABPA并发症占1%至11%。ABPA的基本潜在免疫病理生理过程是对支气管树真菌的超敏反应。患者通常为特应性,既往有支气管哮喘病史。发病隐匿,伴有厌食症、疲劳、体重减轻、头痛、全身疼痛和低烧等体质症状。它的特点是反复发作的恶化与缓解期,如果不治疗可能进展为纤维化肺疾病。慢性纤维化患者可出现紫绀、肺脏病和呼吸衰竭。放射学上短暂的阴影是ABPA的特征。支气管扩张、小叶中心结节和黏液嵌塞是胸部CT扫描ABPA的主要特征。口服皮质类固醇仍然是治疗ABPA的基础。优化基线哮喘治疗是必不可少的。早期诊断和适当治疗可以改变疾病的预后,进一步预防终末期肺纤维化。
{"title":"Allergic bronchopulmonary aspergillosis: Indian scenario","authors":"R. Prasad, R. Kacker, N. Gupta","doi":"10.4103/ijaai.ijaai_37_19","DOIUrl":"https://doi.org/10.4103/ijaai.ijaai_37_19","url":null,"abstract":"Aspergillus is ubiquitous, occurring in mycelial form and grows at 15-530C and humid conditions. Pulmonary aspergillosis is a clinical spectrum of lung disease caused by the fungus Aspergillus. ABPA is the commonest disease among allergic bronchopulmonary mycoses. The exact prevalence of ABPA is not known but contemporary estimates suggested that ABPA complicates 1 to 11% of all chronic cases of bronchial asthma. The basic underlying immuno-pathophysiologic process in ABPA is a hypersensitivity reaction to fungus in the bronchial tree. Patients are usually atopic with previous history of bronchial asthma. The onset is insidious with constitutional symptoms like anorexia, fatigue, weight loss, headache, generalized aches and pains, and low-grade fever. It is characterized by repeated episodes of exacerbation with periods of remission, if untreated may progress to fibrotic lung disease. Patients with chronic fibrotic disease may present with cyanosis, corpulmonale and respiratory failure. Radiologically fleeting shadows are characteristic of ABPA. Bronchiectasis, centrilobular nodules and mucoid impaction are main features of ABPA seen in CT scan thorax. Oral corticosteroid remains the cornerstone for the treatment of ABPA. Optimization of baseline asthma therapy is essential. Early diagnosis and proper treatment may alter the prognosis of disease and further prevent end stage lung fibrosis.","PeriodicalId":53075,"journal":{"name":"Indian Journal of Allergy Asthma and Immunology","volume":"301 1","pages":"63 - 69"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90804264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A study to compare pulmonary function in apparently healthy females exposed to biomass fuel combustion versus clean fuel combustion in Allahabad District 比较阿拉哈巴德地区暴露于生物质燃料燃烧与清洁燃料燃烧的表面健康女性肺功能的研究
Pub Date : 2019-07-01 DOI: 10.4103/ijaai.ijaai_4_19
T. Mahmood, Ashish Jain, A. Verma, Pundarik Dwivedi
BACKGROUND: Life in a typical Indian household revolves around the cooking area, and Indian women spend much of their time there. Cooking stoves in biomass fuel users are nothing more than a pit, a chulha, or three pieces of brick. Cooking under these conditions entails high levels of exposure to cooking smoke. AIMS AND OBJECTIVES: (1) To compare the pulmonary function parameters of biomass fuel users with clean fuel users. (2) To evaluate the pulmonary function test (PFT) among individuals exposed to biomass fuel combustion. MATERIALS AND METHODS: Three hundred and fourteen nonsmoking women without any history of any major chronic illness in the past were selected for this study. The study group comprised of 68 women exposed to biomass fuel combustion, 105 women exposed to clean fuel combustion, and 141 women exposed to mixed fuel (earlier using biomass fuel but now gradually shifting to clean fuel). All women were evaluated for PFTs MIR spirolab III. OBSERVATION AND RESULTS: The lung function parameters were significantly lower in the women exposed to biomass fuel in comparison to the clean fuel users and mixed fuel users forced expiratory volume 1 (FEV1) (P < 0.05); FEV1/forced vital capacity (FVC) (P < 0.05); FVC (P < 0.05); peak expiratory flow rate (PEFR) (P < 0.05); the lung function parameters were also significantly reduced in group of mixed fuel users in comparison to the group of clean fuel users FEV1 (P < 0.05); FEV1/FVC (P < 0.05); FVC (P < 0.05); PEFR (P < 0.05). The evaluation of PFTs suggested the increased risk to the obstructive type of pulmonary disease in biomass users. CONCLUSION: The reduction in the pulmonary function in the biomass-exposed women could be due to high exposure to biomass pollutants with inadequate ventilation in cooking area.
背景:典型印度家庭的生活围绕着烹饪区展开,印度妇女的大部分时间都花在烹饪上。生物质燃料使用者的炉灶只不过是一个坑,一个chulha或三块砖。在这些条件下烹饪需要高度暴露于烹饪烟雾中。目的和目的:(1)比较生物质燃料使用者和清洁燃料使用者的肺功能参数。(2)评价生物质燃料燃烧暴露个体的肺功能测试(PFT)。材料和方法:本研究选择了314名过去没有任何重大慢性疾病史的不吸烟女性。研究小组由68名接触生物质燃料燃烧的妇女、105名接触清洁燃料燃烧的妇女和141名接触混合燃料(早期使用生物质燃料,但现在逐渐转向使用清洁燃料)的妇女组成。对所有女性进行PFTs - MIR - spirallab III评估。观察与结果:与清洁燃料使用者和混合燃料使用者相比,暴露于生物质燃料的女性肺功能参数显著降低(P < 0.05);FEV1/用力肺活量(FVC) (P < 0.05);FVC (p < 0.05);呼气流量峰值(PEFR) (P < 0.05);混合燃料组肺功能参数FEV1较清洁燃料组显著降低(P < 0.05);Fev1 / fvc (p < 0.05);FVC (p < 0.05);(p < 0.05)。对PFTs的评估表明,生物质使用者患阻塞性肺病的风险增加。结论:生物质暴露妇女肺功能下降可能与炊事区高暴露于生物质污染物且通风不良有关。
{"title":"A study to compare pulmonary function in apparently healthy females exposed to biomass fuel combustion versus clean fuel combustion in Allahabad District","authors":"T. Mahmood, Ashish Jain, A. Verma, Pundarik Dwivedi","doi":"10.4103/ijaai.ijaai_4_19","DOIUrl":"https://doi.org/10.4103/ijaai.ijaai_4_19","url":null,"abstract":"BACKGROUND: Life in a typical Indian household revolves around the cooking area, and Indian women spend much of their time there. Cooking stoves in biomass fuel users are nothing more than a pit, a chulha, or three pieces of brick. Cooking under these conditions entails high levels of exposure to cooking smoke. AIMS AND OBJECTIVES: (1) To compare the pulmonary function parameters of biomass fuel users with clean fuel users. (2) To evaluate the pulmonary function test (PFT) among individuals exposed to biomass fuel combustion. MATERIALS AND METHODS: Three hundred and fourteen nonsmoking women without any history of any major chronic illness in the past were selected for this study. The study group comprised of 68 women exposed to biomass fuel combustion, 105 women exposed to clean fuel combustion, and 141 women exposed to mixed fuel (earlier using biomass fuel but now gradually shifting to clean fuel). All women were evaluated for PFTs MIR spirolab III. OBSERVATION AND RESULTS: The lung function parameters were significantly lower in the women exposed to biomass fuel in comparison to the clean fuel users and mixed fuel users forced expiratory volume 1 (FEV1) (P < 0.05); FEV1/forced vital capacity (FVC) (P < 0.05); FVC (P < 0.05); peak expiratory flow rate (PEFR) (P < 0.05); the lung function parameters were also significantly reduced in group of mixed fuel users in comparison to the group of clean fuel users FEV1 (P < 0.05); FEV1/FVC (P < 0.05); FVC (P < 0.05); PEFR (P < 0.05). The evaluation of PFTs suggested the increased risk to the obstructive type of pulmonary disease in biomass users. CONCLUSION: The reduction in the pulmonary function in the biomass-exposed women could be due to high exposure to biomass pollutants with inadequate ventilation in cooking area.","PeriodicalId":53075,"journal":{"name":"Indian Journal of Allergy Asthma and Immunology","volume":"948 1","pages":"79 - 85"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72673159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
B cell counterpart of Treg cells: As a new target for autoimmune disease therapy Treg细胞的B细胞对应物:作为自身免疫性疾病治疗的新靶点
Pub Date : 2019-07-01 DOI: 10.4103/ijaai.ijaai_27_18
Myong-Guk Ri, Cholho Kang
B cells have been considered a positive immune regulator by producing antibodies and presenting antigens to T cells. Recently, it has been shown that B cells comprise rare but potent subset capable of inhibiting immune responses via diverse regulatory mechanisms. This subset of B cells, known as regulatory B cells (Bregs), negatively regulates immune responses and contributes to immune tolerance. Among several regulatory B cell subsets, interleukin 10 (IL-10)-producing regulatory B cells are intensively investigated. Studies in experimental animal models, as well as in patients with autoimmune diseases, have identified Breg subsets exhibiting a powerful therapeutic tool for severe immune disorders. Now, human regulatory B cells are becoming an active area of research. Clear criteria to identify these cell subsets and the key molecular mechanisms underlying their physiological features are required for understanding the complete picture of regulatory B cells. This review highlights the current knowledge on regulatory B cells, mainly IL-10-producing regulatory B cells.
B细胞通过产生抗体和向T细胞呈递抗原而被认为是一种积极的免疫调节剂。最近,研究表明B细胞包含罕见但有效的亚群,能够通过多种调节机制抑制免疫反应。B细胞的这一部分,被称为调节性B细胞(Bregs),负调节免疫反应并有助于免疫耐受。在几个调节性B细胞亚群中,产生白细胞介素10 (IL-10)的调节性B细胞被广泛研究。对实验动物模型以及自身免疫性疾病患者的研究已经确定Breg亚群对严重免疫疾病表现出强大的治疗工具。现在,人类调节性B细胞正在成为一个活跃的研究领域。了解调节性B细胞的全貌需要明确的标准来识别这些细胞亚群及其生理特征背后的关键分子机制。本文综述了目前对调节性B细胞的认识,主要是产生il -10的调节性B细胞。
{"title":"B cell counterpart of Treg cells: As a new target for autoimmune disease therapy","authors":"Myong-Guk Ri, Cholho Kang","doi":"10.4103/ijaai.ijaai_27_18","DOIUrl":"https://doi.org/10.4103/ijaai.ijaai_27_18","url":null,"abstract":"B cells have been considered a positive immune regulator by producing antibodies and presenting antigens to T cells. Recently, it has been shown that B cells comprise rare but potent subset capable of inhibiting immune responses via diverse regulatory mechanisms. This subset of B cells, known as regulatory B cells (Bregs), negatively regulates immune responses and contributes to immune tolerance. Among several regulatory B cell subsets, interleukin 10 (IL-10)-producing regulatory B cells are intensively investigated. Studies in experimental animal models, as well as in patients with autoimmune diseases, have identified Breg subsets exhibiting a powerful therapeutic tool for severe immune disorders. Now, human regulatory B cells are becoming an active area of research. Clear criteria to identify these cell subsets and the key molecular mechanisms underlying their physiological features are required for understanding the complete picture of regulatory B cells. This review highlights the current knowledge on regulatory B cells, mainly IL-10-producing regulatory B cells.","PeriodicalId":53075,"journal":{"name":"Indian Journal of Allergy Asthma and Immunology","volume":"40 1","pages":"70 - 78"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78965632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global warming and allergy 全球变暖和过敏
Pub Date : 2019-07-01 DOI: 10.4103/ijaai.ijaai_32_19
S. Gaur
Global warming is the latest threat to the health all around the world. It effects normal persons and more to those already having disease. The impact of global warming, meaning warmer environment, effects more the respiratory system, especially those having chronic lung diseases, such as chronic obstructive pulmonary disease, interstitial lung disease, asthma, allergies. There is an increase in the frequency and severity of allergic diseases, leading to more hospital visits and admissions. The acute episodes last longer and the response to treatment is slow because of persistent effect of global warming. This has led to the school‐going children, without family history of allergy, to show signs of asthma‐like pattern at very young age.
全球变暖是全球健康面临的最新威胁。它影响正常人,对那些已经患病的人影响更大。全球变暖的影响,意味着环境变暖,对呼吸系统的影响更大,特别是那些患有慢性肺部疾病的人,如慢性阻塞性肺病、间质性肺病、哮喘、过敏。过敏性疾病的发生频率和严重程度都有所增加,导致更多的人去医院就诊和住院。由于全球变暖的持续影响,急性发作持续时间较长,治疗反应缓慢。这导致那些没有过敏家族史的学龄儿童在很小的时候就表现出类似哮喘的症状。
{"title":"Global warming and allergy","authors":"S. Gaur","doi":"10.4103/ijaai.ijaai_32_19","DOIUrl":"https://doi.org/10.4103/ijaai.ijaai_32_19","url":null,"abstract":"Global warming is the latest threat to the health all around the world. It effects normal persons and more to those already having disease. The impact of global warming, meaning warmer environment, effects more the respiratory system, especially those having chronic lung diseases, such as chronic obstructive pulmonary disease, interstitial lung disease, asthma, allergies. There is an increase in the frequency and severity of allergic diseases, leading to more hospital visits and admissions. The acute episodes last longer and the response to treatment is slow because of persistent effect of global warming. This has led to the school‐going children, without family history of allergy, to show signs of asthma‐like pattern at very young age.","PeriodicalId":53075,"journal":{"name":"Indian Journal of Allergy Asthma and Immunology","volume":"199 1","pages":"61 - 62"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79887656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A study of skin prick test sensitivity to common allergens in patients of nasobronchial allergy 鼻支气管变态反应患者皮肤点刺试验对常见变态反应原敏感性的研究
Pub Date : 2019-07-01 DOI: 10.4103/ijaai.ijaai_12_19
S. Karmakar, K. Raza, R. Prasad
BACKGROUND: Nasobronchial allergy accounts for a significant burden of allergy all over the world. The prevalence of nasobronchial allergy is increasing, so we conducted an observational study of common allergens by skin prick test (SPT) method in this group of patients. OBJECTIVE: The objective is to study skin sensitivity to various allergens in patients of nasobronchial allergy, using SPT method. MATERIALS AND METHODS: A total of 6000 SPTs were done using 60 allergens on 100 patients of nasobronchial allergy. RESULTS: Males were the predominant group of patients, and nasobronchial allergy was most common in 21–30 years' age group in our study. Among various groups of allergens studied, insects (24%) were the most common offending allergens, followed by dust mite (20%), airborne dust (11.3%), pollens (7.75%), fungi (6%), dander (6%), silk (4%), juicy foods (2.4%), and nonjuicy foods (2.25%). Among insects, moth (30) was the common allergen. Among dust, grain dust (30) was the common allergen. Among pollens, Cassia siamea (20) was most common. Aspergillus fumigatus (16) was the most common fungus to which sensitivity was elicited. Among miscellaneous foods (juicy and nonjuicy), milk, almonds, and cashew nut (4 each) were the common allergens. CONCLUSION: Skin prick testing forms an essential part of a comprehensive approach for allergy remediation. Our study determined skin sensitivity to various allergens for avoidance therapy and immunotherapy in affected patients. Allergy to insects as found in our study to be most common is likely because of prevailing poor sanitation and overcrowded dwellings in the Indian milieu.
背景:鼻支气管过敏是世界范围内重要的过敏负担。鼻支气管变态反应的发生率越来越高,因此我们对这组患者采用皮肤点刺试验(SPT)法对常见变态反应原进行观察研究。目的:采用SPT法研究鼻支气管变态反应患者皮肤对各种过敏原的敏感性。材料与方法:使用60种过敏原对100例鼻支气管过敏患者进行6000次SPTs。结果:本组患者以男性为主,以21 ~ 30岁年龄组鼻支气管过敏最为常见。在所研究的各种过敏原中,昆虫(24%)是最常见的过敏原,其次是尘螨(20%)、空气粉尘(11.3%)、花粉(7.75%)、真菌(6%)、皮屑(6%)、蚕丝(4%)、多汁食物(2.4%)和非多汁食物(2.25%)。昆虫中,常见的过敏原为飞蛾(30)。粉尘中,谷物粉尘(30)是常见的过敏原。花粉中以决明子(Cassia siamea, 20)最为常见。烟曲霉(Aspergillus fumigatus, 16)是最常见的引起敏感性的真菌。在各种各样的食物(多汁的和不多汁的)中,牛奶、杏仁和腰果(每种4个)是常见的过敏原。结论:皮肤点刺试验是过敏综合治疗的重要组成部分。我们的研究确定皮肤对各种过敏原的敏感性,以避免治疗和免疫治疗受影响的患者。在我们的研究中发现,对昆虫过敏是最常见的,可能是因为印度环境中普遍存在的卫生条件差和过度拥挤的住房。
{"title":"A study of skin prick test sensitivity to common allergens in patients of nasobronchial allergy","authors":"S. Karmakar, K. Raza, R. Prasad","doi":"10.4103/ijaai.ijaai_12_19","DOIUrl":"https://doi.org/10.4103/ijaai.ijaai_12_19","url":null,"abstract":"BACKGROUND: Nasobronchial allergy accounts for a significant burden of allergy all over the world. The prevalence of nasobronchial allergy is increasing, so we conducted an observational study of common allergens by skin prick test (SPT) method in this group of patients. OBJECTIVE: The objective is to study skin sensitivity to various allergens in patients of nasobronchial allergy, using SPT method. MATERIALS AND METHODS: A total of 6000 SPTs were done using 60 allergens on 100 patients of nasobronchial allergy. RESULTS: Males were the predominant group of patients, and nasobronchial allergy was most common in 21–30 years' age group in our study. Among various groups of allergens studied, insects (24%) were the most common offending allergens, followed by dust mite (20%), airborne dust (11.3%), pollens (7.75%), fungi (6%), dander (6%), silk (4%), juicy foods (2.4%), and nonjuicy foods (2.25%). Among insects, moth (30) was the common allergen. Among dust, grain dust (30) was the common allergen. Among pollens, Cassia siamea (20) was most common. Aspergillus fumigatus (16) was the most common fungus to which sensitivity was elicited. Among miscellaneous foods (juicy and nonjuicy), milk, almonds, and cashew nut (4 each) were the common allergens. CONCLUSION: Skin prick testing forms an essential part of a comprehensive approach for allergy remediation. Our study determined skin sensitivity to various allergens for avoidance therapy and immunotherapy in affected patients. Allergy to insects as found in our study to be most common is likely because of prevailing poor sanitation and overcrowded dwellings in the Indian milieu.","PeriodicalId":53075,"journal":{"name":"Indian Journal of Allergy Asthma and Immunology","volume":"255 1","pages":"91 - 97"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77669258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
An inconspicuous agent causing bronchospasm perioperatively: A report on toilet disinfectant liquids 一种引起围手术期支气管痉挛的不明显因素:厕所消毒液的报道
Pub Date : 2019-07-01 DOI: 10.4103/ijaai.ijaai_20_19
Priyanka Gupta, M. Dhar, V. Krishna, A. Barik
A 48‐year‐old female presented to our institute with complaints of right‐sided flank and groin pain for the past 3–4 years, who was diagnosed to have right‐sided lower ureteric stones and was posted for ureteroscopic lithotripsy. Preanesthetic evaluation revealed no major issues or any history suggestive of bronchial asthma and allergy from any drug, dust, and pollen or food allergy. She had undergone three previous uneventful surgeries under both spinal and general anesthesia.
一名48岁女性,因过去3-4年的右侧腹部和腹股沟疼痛来我院就诊,诊断为右侧输尿管下段结石,接受输尿管镜碎石术。麻醉前评估未发现支气管哮喘或药物、粉尘、花粉或食物过敏史。她之前在脊柱和全身麻醉下进行了三次手术,手术都很顺利。
{"title":"An inconspicuous agent causing bronchospasm perioperatively: A report on toilet disinfectant liquids","authors":"Priyanka Gupta, M. Dhar, V. Krishna, A. Barik","doi":"10.4103/ijaai.ijaai_20_19","DOIUrl":"https://doi.org/10.4103/ijaai.ijaai_20_19","url":null,"abstract":"A 48‐year‐old female presented to our institute with complaints of right‐sided flank and groin pain for the past 3–4 years, who was diagnosed to have right‐sided lower ureteric stones and was posted for ureteroscopic lithotripsy. Preanesthetic evaluation revealed no major issues or any history suggestive of bronchial asthma and allergy from any drug, dust, and pollen or food allergy. She had undergone three previous uneventful surgeries under both spinal and general anesthesia.","PeriodicalId":53075,"journal":{"name":"Indian Journal of Allergy Asthma and Immunology","volume":"10 1","pages":"112 - 113"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72838591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of single educational intervention on improving nurses' proficiency in using different inhaler devices in a tertiary care setting 单一教育干预对提高三级医疗机构护士使用不同吸入器装置熟练程度的影响
Pub Date : 2019-07-01 DOI: 10.4103/ijaai.ijaai_22_19
Jaishree Ganjiwale, Ravish M. Kshatriya, Yoshaan Joshi, S. Nimbalkar
CONTEXT: Inhalation medications are administered by different inhalers such as pressurized metered-dose inhaler (pMDI) with or without the spacer, dry-powder inhaler (DPI), and nebulizer. Many health-care providers including nurses may have deficiencies in knowledge about using inhalers. This can result in improper techniques of using inhalers adapted by patients, which may lead to wastage of time, medicine, and money and thereby poor outcome in terms of relief. AIMS: The aim is to study the proficiency of inhalers in nurses and the effect of educational intervention to improve the same. SETTINGS AND DESIGN: It was a hospital-based educational interventional type of study. SUBJECTS AND METHODS: Technique of usage of inhalers in 87 nurses was assessed. The steps assessed were as follows (1) Preparation, (2) Administration, (3) Inhalation, (4) Coordination, and finally, (5) Instructions given to patients. Important and necessary steps such as able to identify empty device, advising mouth gargles after administration of the drug via the inhaler device and proper breath holding were also assessed. After an initial assessment, nurses were given an individualized educational session regarding the correct usage of various inhaler devices. They were again reevaluated after one month for the same. STATISTICAL ANALYSIS USED: The proportion of the participants performing the steps properly before and after the intervention was calculated and compared with Z-test for proportions. The relationship between the years of experience and score for task post intervention was seen through Karl Pearson's correlation coefficient (r). RESULTS: After the intervention, the proficiency of nurses with the use of each device improved as follows: for pMDI from 21.8% to 36.8%, for DPI from 21.8% to 62.18%, for pMDI with spacer from 2.3% to 21.%, and for nebulizer from 33.3% to 53.21%. For important steps such as identification of empty MDI, only 28.7% of the nurses did it correctly, which improved to 64.4% after the intervention. For proper holding of the device, the proficiency of nurses increased from 29.9% to 69.7%. For proper coordination, the proficiency increased from 18.39% to 67.1%. About 11.4% of the nurses held breath correctly before, which improved to 60.5% after teaching. About 40.2% of the nurses advised gargles after using inhalers before the intervention, which improved to 86.8% afterward. CONCLUSIONS: Our individualized training has made a difference and improved knowledge as well as skills regarding the use of different inhaler devices in nurses, although there is still a lot of scope for further improvement.
背景:吸入性药物由不同的吸入器给药,如带或不带间隔器的加压计量吸入器(pMDI)、干粉吸入器(DPI)和雾化器。包括护士在内的许多保健提供者可能缺乏使用吸入器的知识。这可能导致患者使用吸入器的技术不正确,这可能导致时间、药物和金钱的浪费,从而导致缓解效果不佳。目的:了解护士对吸入器的熟练程度及教育干预的效果。背景和设计:这是一项以医院为基础的教育介入类型的研究。对象与方法:对87名护士吸入器的使用技术进行评估。评估的步骤如下:(1)准备,(2)给药,(3)吸入,(4)协调,最后(5)给患者的指导。还评估了重要和必要的步骤,例如能够识别空装置,建议通过吸入器装置给药后漱口和适当屏气。初步评估后,护士被给予关于正确使用各种吸入器装置的个体化教育会议。一个月后,他们再次接受了同样的评估。统计分析使用:计算干预前后正确执行步骤的参与者的比例,并使用z检验进行比例比较。通过Karl Pearson相关系数(r)观察任务岗位干预的经验年数与得分之间的关系。结果:干预后,护士对各设备的使用熟练程度提高如下:pMDI从21.8%提高到36.8%,DPI从21.8%提高到62.18%,带间隔的pMDI从2.3%提高到21%。%,雾化器为33.3% ~ 53.21%。对于识别空MDI等重要步骤,只有28.7%的护士正确完成,干预后这一比例提高到64.4%。护士对器械正确握持的熟练程度由29.9%提高到69.7%。对于适当的协调,熟练程度从18.39%提高到67.1%。教学前正确屏气率为11.4%,教学后提高至60.5%。干预前约有40.2%的护士建议使用吸入器后漱口,干预后这一比例提高至86.8%。结论:我们的个性化培训已经发挥了作用,提高了护士使用不同吸入器装置的知识和技能,尽管仍有很大的改进空间。
{"title":"The effect of single educational intervention on improving nurses' proficiency in using different inhaler devices in a tertiary care setting","authors":"Jaishree Ganjiwale, Ravish M. Kshatriya, Yoshaan Joshi, S. Nimbalkar","doi":"10.4103/ijaai.ijaai_22_19","DOIUrl":"https://doi.org/10.4103/ijaai.ijaai_22_19","url":null,"abstract":"CONTEXT: Inhalation medications are administered by different inhalers such as pressurized metered-dose inhaler (pMDI) with or without the spacer, dry-powder inhaler (DPI), and nebulizer. Many health-care providers including nurses may have deficiencies in knowledge about using inhalers. This can result in improper techniques of using inhalers adapted by patients, which may lead to wastage of time, medicine, and money and thereby poor outcome in terms of relief. AIMS: The aim is to study the proficiency of inhalers in nurses and the effect of educational intervention to improve the same. SETTINGS AND DESIGN: It was a hospital-based educational interventional type of study. SUBJECTS AND METHODS: Technique of usage of inhalers in 87 nurses was assessed. The steps assessed were as follows (1) Preparation, (2) Administration, (3) Inhalation, (4) Coordination, and finally, (5) Instructions given to patients. Important and necessary steps such as able to identify empty device, advising mouth gargles after administration of the drug via the inhaler device and proper breath holding were also assessed. After an initial assessment, nurses were given an individualized educational session regarding the correct usage of various inhaler devices. They were again reevaluated after one month for the same. STATISTICAL ANALYSIS USED: The proportion of the participants performing the steps properly before and after the intervention was calculated and compared with Z-test for proportions. The relationship between the years of experience and score for task post intervention was seen through Karl Pearson's correlation coefficient (r). RESULTS: After the intervention, the proficiency of nurses with the use of each device improved as follows: for pMDI from 21.8% to 36.8%, for DPI from 21.8% to 62.18%, for pMDI with spacer from 2.3% to 21.%, and for nebulizer from 33.3% to 53.21%. For important steps such as identification of empty MDI, only 28.7% of the nurses did it correctly, which improved to 64.4% after the intervention. For proper holding of the device, the proficiency of nurses increased from 29.9% to 69.7%. For proper coordination, the proficiency increased from 18.39% to 67.1%. About 11.4% of the nurses held breath correctly before, which improved to 60.5% after teaching. About 40.2% of the nurses advised gargles after using inhalers before the intervention, which improved to 86.8% afterward. CONCLUSIONS: Our individualized training has made a difference and improved knowledge as well as skills regarding the use of different inhaler devices in nurses, although there is still a lot of scope for further improvement.","PeriodicalId":53075,"journal":{"name":"Indian Journal of Allergy Asthma and Immunology","volume":"34 1","pages":"86 - 90"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89327566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Dr. VK Vijayan (19.06.1948–29.01.2019)
Pub Date : 2019-07-01 DOI: 10.4103/ijaai.ijaai_24_19
A. Singh
{"title":"Dr. VK Vijayan (19.06.1948–29.01.2019)","authors":"A. Singh","doi":"10.4103/ijaai.ijaai_24_19","DOIUrl":"https://doi.org/10.4103/ijaai.ijaai_24_19","url":null,"abstract":"","PeriodicalId":53075,"journal":{"name":"Indian Journal of Allergy Asthma and Immunology","volume":"35 1","pages":"114 - 115"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85378360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Indian Journal of Allergy Asthma and Immunology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1