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Correction Notice. 更正通知。
IF 2.1 Q3 CLINICAL NEUROLOGY Pub Date : 2026-01-14 eCollection Date: 2025-01-01 DOI: 10.1080/24740527.2025.2600250

[This corrects the article DOI: 10.1080/24740527.2025.2486835.].

[这更正了文章DOI: 10.1080/24740527.2025.2486835.]。
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引用次数: 0
Multidimensional experience of pain in adults with cirrhosis: A qualitative descriptive study. 成人肝硬化患者疼痛的多维体验:一项定性描述性研究。
IF 2.1 Q3 CLINICAL NEUROLOGY Pub Date : 2025-12-15 eCollection Date: 2025-01-01 DOI: 10.1080/24740527.2025.2573273
Franklin F F Gorospe, David Wong, Elizabeth Lee, Lissi Hansen, Martine Puts, Craig M Dale

The incidence of liver disease is projected to increase significantly by 2030, affecting 1.5 billion of the global population and approximately 3 million in Canada. With various etiologies, the progression of liver disease to cirrhosis varies from months, years, or decades. Experiencing pain can severely debilitate a person living with this condition. However, there is limited qualitative evidence to understand the subjective pain experience of individuals with cirrhosis. Understanding this experience with cirrhosis is crucial for providing comprehensive, person-centered care. The aim of this study was to qualitatively explore the multidimensional experience of pain for persons with cirrhosis. A qualitative descriptive approach was used, recruiting participants from a hepatology clinic in Toronto in 2021. Participants completed a Brief Pain Inventory Short Form questionnaire and a semistructured interview. Data analysis was guided by Hsieh and Shannon's stepwise directed content analysis. Fifteen interviews were conducted with adults (mean age: 54 years, 53% men, 47% women) with cirrhosis, most unable to work, with approximately half married/partnered. Participants reported diverse physical symptoms including visceral and musculoskeletal pain, often described as a constant experience. Psychologically, pain contributed to significant fatigue and emotional distress, affecting self-care and daily activities. Socioculturally, pain disrupted social interactions and financial stability, intensifying reliance on support systems. Participants reported limited effectiveness of pharmacological interventions, reliance on mindfulness and rest, and frustration with unmet pain management needs. These interrelated themes collectively impaired quality of life and independence. Exploring the multidimensionality of pain for persons with cirrhosis provides valuable insights to address the gaps in current pain management strategies.

预计到2030年,肝病的发病率将显著增加,影响全球15亿人口,加拿大约有300万人。由于各种病因,肝病发展为肝硬化的时间从几个月、几年到几十年不等。经历疼痛会使患有这种疾病的人严重衰弱。然而,有有限的定性证据来了解肝硬化患者的主观疼痛体验。了解肝硬化患者的这种经历对于提供全面的、以人为本的护理至关重要。本研究的目的是定性地探讨肝硬化患者疼痛的多维体验。采用定性描述方法,于2021年从多伦多的一家肝病诊所招募参与者。参与者完成了一份简短的疼痛量表和一份半结构化的访谈。数据分析以Hsieh和Shannon的逐步定向内容分析为指导。对15名患有肝硬化的成年人(平均年龄:54岁,53%男性,47%女性)进行了访谈,大多数无法工作,大约一半已婚/有伴侣。参与者报告了不同的身体症状,包括内脏和肌肉骨骼疼痛,通常被描述为一种持续的经历。从心理上讲,疼痛会导致严重的疲劳和情绪困扰,影响自我照顾和日常活动。在社会文化方面,疼痛破坏了社会互动和金融稳定,加剧了对支持系统的依赖。参与者报告药物干预的有效性有限,依赖于正念和休息,以及对未满足的疼痛管理需求感到沮丧。这些相互关联的主题共同损害了生活质量和独立性。探索肝硬化患者疼痛的多维度为解决当前疼痛管理策略的空白提供了有价值的见解。
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引用次数: 0
Implementing pain competencies in Canadian physiotherapy education: Challenges, barriers, and opportunities. 在加拿大物理治疗教育中实施疼痛能力:挑战、障碍和机遇。
IF 2.1 Q3 CLINICAL NEUROLOGY Pub Date : 2025-12-15 eCollection Date: 2025-01-01 DOI: 10.1080/24740527.2025.2574969
Nathan Augeard, Christian Longtin, André Bussières, Geoff Bostick, Aliki Thomas, Jordan Miller, Yannick Tousignant-Laflamme, David Walton, Anne Hudon, Lynn Cooper, Lesley Singer, Fatima Amari, Timothy H Wideman

Background: The Pain Education in Physiotherapy (PEP) competency profile provides a structured framework for integrating pain management competencies into Canadian physiotherapy (PT) curricula. Despite widespread endorsement, the integration of pain management competencies into PT curricula remains inconsistent. Identifying the barriers and enablers to implementation is essential for developing strategies that support students in achieving these competencies.

Objective: This study explored factors influencing the implementation of the PEP competency profile in Canadian PT programs and identified key challenges and opportunities for improving integration.

Methods: A qualitative description study was conducted using five focus groups with 23 participants, including pain educators and program directors from 13 entry-level PT programs in Canada. Data were analyzed using the Consolidated Framework for Implementation Research to identify multilevel barriers and facilitators.

Results: Participants recognized the value of the PEP competency profile in enhancing pain education but highlighted three key challenges: (1) a lack of structured guidance for teaching and assessment, (2) an overreliance on faculty champions rather than systemic institutional support, and (3) the absence of rigorous assessment approaches. Participants expressed uncertainty about integrating competencies within existing curricula, emphasizing the need for national collaboration, faculty development, and shared resources. The iterative, decentralized nature of curriculum change further complicated efforts to achieve consistent integration.

Conclusion: Sustainable implementation of the PEP competencies requires structured guidance, institutional commitment, and adapted assessment strategies. Addressing these barriers through national-level collaboration, accreditation alignment, and faculty support is critical to ensure that PT graduates develop the necessary competencies for high-quality pain management.

背景:物理治疗中的疼痛教育(PEP)能力概况为将疼痛管理能力整合到加拿大物理治疗(PT)课程中提供了一个结构化框架。尽管广泛认可,疼痛管理能力整合到PT课程仍然不一致。确定实施的障碍和推动因素对于制定支持学生实现这些能力的战略至关重要。目的:本研究探讨了影响加拿大体育训练项目实施PEP胜任力概况的因素,并确定了改善整合的主要挑战和机遇。方法:采用5个焦点小组进行定性描述研究,共有23名参与者,包括来自加拿大13个入门级PT项目的疼痛教育者和项目主管。使用实施研究综合框架对数据进行了分析,以确定多层次障碍和促进因素。结果:参与者认识到PEP能力特征在加强疼痛教育方面的价值,但强调了三个关键挑战:(1)缺乏结构化的教学和评估指导;(2)过度依赖教师支持者而不是系统的机构支持;(3)缺乏严格的评估方法。与会者表达了将能力整合到现有课程中的不确定性,强调了国家合作、师资发展和资源共享的必要性。课程变化的迭代性、分散性使实现一致整合的努力进一步复杂化。结论:PEP能力的可持续实施需要结构化的指导、制度承诺和适应的评估策略。通过国家级合作、认证一致性和教师支持来解决这些障碍,对于确保PT毕业生培养高质量疼痛管理所需的能力至关重要。
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引用次数: 0
The stigmatization of patients with chronic pain due to assessed exaggeration of symptoms. 慢性疼痛患者因被评估的症状夸大而被污名化。
IF 2.1 Q3 CLINICAL NEUROLOGY Pub Date : 2025-12-15 eCollection Date: 2025-01-01 DOI: 10.1080/24740527.2025.2583909
Hance Clarke, Kenneth Craig, Rodrigo Deamo Assis, Nimish Mittal, Mary-Ann Fitzcharles

Patients with chronic pain that cannot be explained by tissue abnormality may be accused of symptom amplification and at worst malingering. This is particularly relevant in the medicolegal setting where legal decisions are highly dependent on objective and validated information, conditions mostly lacking in the setting of chronic pain. When evaluations are conducted by assessors less familiar with current knowledge of pain mechanisms, subjective complaints of pain and associated symptoms such as fatigue and cognitive difficulties, are at risk of being misinterpreted leading to bias and stigmatization. In this commentary we will highlight some of the pitfalls that erroneously lead to a biased assessment of pain severity including failure to pay attention to psychological state and sociocultural influences, application of poorly reliable physical maneuvers, and use of neurocognitive testing of intentional cognitive dysfunction as a surrogate for dishonesty in pain and functional impairment report. Concerns about misinterpretation of exaggeration in persons with chronic pain are highlighted by recent report of symptom exaggeration in up to two thirds of those attending for an independent medical evaluation. Directives to help the medical assessor to provide pertinent information that will assist the courts in reaching a fair decision are discussed, with emphasis on need for a comprehensive assessment of biosocial factors, contextual variables and nonphysical evidence.

不能用组织异常解释的慢性疼痛患者可能被指责为症状放大,最坏的情况是装病。这在医学法律环境中尤其重要,因为法律决定高度依赖于客观和有效的信息,而慢性疼痛的环境大多缺乏这些条件。当评估人员不太熟悉当前的疼痛机制知识时,主观的疼痛主诉和相关症状,如疲劳和认知困难,有可能被误解,导致偏见和污名化。在这篇评论中,我们将强调一些错误地导致对疼痛严重程度有偏见的评估的陷阱,包括未能注意心理状态和社会文化影响,应用不可靠的身体动作,以及使用故意认知功能障碍的神经认知测试来代替疼痛和功能损伤报告中的不诚实。最近有报告称,在接受独立医学评估的患者中,多达三分之二的人出现了症状夸大,这突显了对慢性疼痛患者夸大症状的误解。讨论了帮助医疗评估人员提供有助于法院作出公正裁决的相关信息的指示,重点是需要对生物社会因素、背景变量和非物证进行全面评估。
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引用次数: 0
The impact of chronic pain on adolescents and their families: A qualitative investigation of parental perspectives. 慢性疼痛对青少年及其家庭的影响:父母视角的定性调查。
IF 2.1 Q3 CLINICAL NEUROLOGY Pub Date : 2025-12-08 eCollection Date: 2025-01-01 DOI: 10.1080/24740527.2025.2562440
Lindsay Sullivan, Ellie Ferguson, Harrison Vriese, Kathleen Lemanek, Lindsey Vater, Sharon Wrona, Lauren Renner, Megan Armstrong, Hannah Williams, Henry Xiang

Background: Understanding the experiences of parents of adolescents with chronic pain is crucial in creating a better experience for all involved throughout the adolescent's chronic pain journey. However, limited qualitative research has explored the experiences of parents of adolescents with chronic pain.

Aims: This qualitative study explored the lived experiences of parents of adolescents with chronic pain, with a focus on the impact of chronic pain on their child and family life. Methods: We conducted 12 semi-structured interviews with parents of adolescents with chronic pain receiving care through a pain management program. Data were transcribed and analyzed using inductive thematic analysis.

Results: Seven key themes were generated and divided into two groups: (1) adolescent and (2) family (including both parents and siblings). Groups were determined based on whether the theme referred to the effect of chronic pain on the adolescent or the caregiver or family. The adolescent group included four themes: (1) physical, (2) psychological, (3) social interaction, and (4) school functioning. The family group included three themes: (1) disruption to daily life, (2) emotional, and (3) relationship dynamics.

Conclusions: This study provides a deeper understanding of the negative effect chronic pain can have on adolescents and family life. Our findings call for interventions to mitigate the physical, psychological, and social impact of chronic pain on adolescents. Family level interventions are also needed to support families of adolescents with chronic pain. More research is needed to explore adolescents' own views of their experiences with chronic pain.

背景:了解患有慢性疼痛的青少年父母的经历对于在青少年的慢性疼痛之旅中为所有参与者创造更好的体验至关重要。然而,有限的定性研究已经探讨了青少年慢性疼痛的父母的经验。目的:本定性研究探讨慢性疼痛青少年父母的生活经历,重点关注慢性疼痛对他们的孩子和家庭生活的影响。方法:我们对接受疼痛管理项目治疗的青少年慢性疼痛患者的父母进行了12次半结构化访谈。对数据进行转录和归纳主题性分析。结果:产生了七个关键主题,并分为两组:(1)青少年和(2)家庭(包括父母和兄弟姐妹)。分组是根据主题是否涉及慢性疼痛对青少年或照顾者或家庭的影响来确定的。青少年组包括四个主题:(1)身体,(2)心理,(3)社会互动,(4)学校功能。家庭组包括三个主题:(1)日常生活的中断,(2)情感,(3)关系动态。结论:本研究对慢性疼痛对青少年和家庭生活的负面影响提供了更深入的了解。我们的研究结果呼吁采取干预措施来减轻慢性疼痛对青少年的身体、心理和社会影响。家庭层面的干预也需要支持患有慢性疼痛的青少年的家庭。需要更多的研究来探索青少年自己对慢性疼痛经历的看法。
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引用次数: 0
What can the Global South learn from Canada's innovations in pain science? 全球南方国家可以从加拿大在疼痛科学方面的创新中学到什么?
IF 2.1 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-25 eCollection Date: 2025-01-01 DOI: 10.1080/24740527.2025.2541108
Jose Eric M Lacsa

Canada's advancements in pain research, characterized by innovative education, clinical care, and trainee-led scholarship, offer valuable insights for the Global South. This article examines key initiatives highlighted in a recent Canadian Journal of Pain special issue, including multidisciplinary approaches, patient-centered care, and the development of accessible pain assessment tools. By contextualizing these innovations within the Philippine healthcare landscape, the article explores challenges such as limited access, cultural perceptions of pain, and under-resourced pain management systems. Emphasizing the importance of narrative-driven and culturally sensitive methodologies, it advocates for integrating indigenous knowledge and community participation into pain research and care. Furthermore, the article underscores the critical role of nurturing early-career researchers and fostering cross-sector collaboration to build sustainable pain research ecosystems. Ultimately, this reflection invites Global South countries to adapt and co-create pain science innovations, contributing to a more inclusive and globally connected understanding of pain management. The article serves as a call to reimagine pain research that bridges local realities with global expertise, fostering equitable health outcomes across diverse populations.

加拿大在疼痛研究方面的进步,以创新教育、临床护理和实习生主导的奖学金为特征,为全球南方提供了宝贵的见解。本文探讨了最近加拿大疼痛杂志特刊中突出的关键举措,包括多学科方法,以患者为中心的护理,以及可访问的疼痛评估工具的发展。通过将菲律宾医疗保健领域的这些创新置于背景下,本文探讨了诸如有限的访问、对疼痛的文化认知和资源不足的疼痛管理系统等挑战。它强调叙述驱动和文化敏感方法的重要性,倡导将土著知识和社区参与纳入疼痛研究和护理。此外,文章强调了培养早期职业研究人员和促进跨部门合作以建立可持续的疼痛研究生态系统的关键作用。最终,这一反思邀请全球南方国家适应并共同创造疼痛科学创新,促进对疼痛管理的更具包容性和全球联系的理解。这篇文章呼吁重新构想疼痛研究,将当地现实与全球专业知识联系起来,在不同人群中促进公平的健康结果。
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引用次数: 0
Winner of the Ronald Melzack-Canadian Journal of Pain Paper of the Year Award for 2024/Récipiendaire du Prix Ronald Melzack Pour L'Année 2024 Des Articles Parus Dans La Revue Canadienne de La Douleur. 获得Ronald Melzack-加拿大杂志2024年年度疼痛纸奖/获得Ronald Melzack Pour L' Annee 2024年Des Articles Parus Dans La Revue Canadienne de La Douleur奖。
IF 2.1 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-04 eCollection Date: 2025-01-01 DOI: 10.1080/24740527.2025.2544489
Joel Katz, Heather Lumsden-Ruegg, Anna Waisman
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引用次数: 0
The effects of traumatic pain memories on current pain experience in men with hemophilia. 创伤性疼痛记忆对血友病患者当前疼痛体验的影响。
IF 2.1 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-04 eCollection Date: 2025-01-01 DOI: 10.1080/24740527.2025.2530966
Anna Wells, Debra Gray, Margaret Husted, David Stephensen

Hemophilia is a bleeding disorder characterized by recurrent bleeding into muscles and joints. Many people with hemophilia experience multiple traumatic painful bleeding episodes, meaning that pain is often a significant problem for people with hemophilia, with a potentially high prevalence of posttraumatic stress and posttraumatic stress disorder symptoms. Current pain treatments are often ineffective and do not consider pain memories, which are experienced by almost half of people with posttraumatic stress disorder and which has not been explored in people with hemophilia. To fill this gap, 14 semistructured interviews with men with hemophilia were completed between November 2022 and January 2023 to explore their lived experiences of pain relating to their hemophilia. Data were analyzed using reflexive thematic analysis. Three overarching themes were constructed from the data: "trauma histories," "pain management," and "impact on the present." Findings show that pain experienced by people with hemophilia is complex and does include a memory element for many individuals. Pain memories are clear and vivid and include visual, somatic, and emotional elements in intricate detail. Pain can also be experienced in the present when experiencing a pain flashback, and pain in the present can be a trigger to recalling and re-experiencing pain memories from the past. Self-taught active dissociation from pain, imagery, and distraction were described as useful pain management strategies. Findings from this study have implications for clinicians and service providers because current pharmacological and physical pain management techniques may be ineffective when pain memory is involved. Future interventions should consider how pain management is advanced for people with hemophilia and how hemophilia services become trauma informed.

血友病是一种以反复出血进入肌肉和关节为特征的出血性疾病。许多血友病患者会经历多次创伤性疼痛出血,这意味着疼痛通常是血友病患者的一个重要问题,可能会导致创伤后应激障碍和创伤后应激障碍症状的高发。目前的疼痛治疗通常是无效的,而且没有考虑到疼痛记忆,几乎一半的创伤后应激障碍患者都经历过疼痛记忆,而在血友病患者中还没有进行过探索。为了填补这一空白,研究人员在2022年11月至2023年1月期间完成了对血友病男性患者的14次半结构化访谈,以探索他们与血友病相关的疼痛生活经历。数据分析采用反身性主题分析。从数据中构建了三个主要主题:“创伤历史”、“疼痛管理”和“对现在的影响”。研究结果表明,血友病患者所经历的疼痛是复杂的,对许多人来说确实包括记忆因素。疼痛记忆清晰而生动,包括视觉、身体和情感的复杂细节。当经历疼痛闪回时,也可以在现在体验到疼痛,并且现在的疼痛可以触发回忆和重新体验过去的疼痛记忆。自学主动分离疼痛、想象和分心被描述为有用的疼痛管理策略。这项研究的发现对临床医生和服务提供者具有启示意义,因为当涉及疼痛记忆时,当前的药物和物理疼痛管理技术可能无效。未来的干预措施应考虑如何对血友病患者进行先进的疼痛管理,以及血友病服务如何成为创伤知情的。
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引用次数: 0
Editorial to accompany the special issue: Social and health inequities in chronic pain across the life span. 特刊附社论:慢性疼痛在整个生命周期中的社会和健康不平等。
IF 2.1 Q3 CLINICAL NEUROLOGY Pub Date : 2025-08-21 eCollection Date: 2024-01-01 DOI: 10.1080/24740527.2025.2533301
Fiona Webster, Leigha Comer, Abhimanyu Sud, Kara Turcotte, Joel Katz
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引用次数: 0
Opioid analgesics for chronic noncancer pain in patients prescribed opioid agonist therapy or with opioid use disorder: A systematic review. 阿片类镇痛药用于处方阿片类激动剂治疗或阿片类药物使用障碍患者的慢性非癌性疼痛:一项系统综述。
IF 2.1 Q3 CLINICAL NEUROLOGY Pub Date : 2025-07-31 eCollection Date: 2025-01-01 DOI: 10.1080/24740527.2025.2499553
Vahid Ashoorion, Tushar Sood, Shezel Muneer, Jason W Busse, Danielle Rice, Jaris Swidrovich, Umair Majid, James Abesteh, Randi Q Mao, Abhimanyu Sud

Background: Opioid use disorder (OUD) is a growing public health concern in North America, often coexisting with chronic noncancer pain (CNCP). Managing both conditions presents unique challenges, highlighting the need for evidence to guide decision making.

Aim: The study aimed to conduct a systematic review that summarizes evidence on the efficacy, effectiveness, and safety of opioid analgesics alone or in combination with opioid agonist therapy (OAT) to manage CNCP in people with OUD or with a history of OUD.

Methods: We searched MEDLINE, Embase, PsycINFO, CINAHL and AMED from inception to July 2023 for randomized studies and up to January 2025 for non-randomized studies that explored the efficacy, effectiveness, and safety of opioids for people living with chronic pain and current or prior OUD. We assessed the risk of bias in included studies, evaluated the quality of evidence using the GRADE approach, and provided a narrative summary of treatment effects.

Results: Our search identified 15,988 unique citations, of which six observational studies were deemed eligible to inform safety outcomes for review, while no observational studies or RCTs met the eligibility criteria for efficacy or effectiveness outcomes. The likelihood of suicidality was twice as high in CNCP patients with OUD receiving long-term opioid analgesics compared to those without OUD (absolute risk increase: 127; 95% CI: 36 to 249 more participants with suicidality in 1,000 participants; moderate certainty evidence). Compared to opioid analgesics alone, the risk of fatal opioid-related overdose may decrease in patients with CNCP and OUD who receive both opioid analgesics and OAT (absolute risk reduction: 60; 95%CI: 18 to 94 fewer deaths in 1,000 participants; low certainty evidence).

Conclusions: There is a paucity of evidence to inform practice and policy regarding opioid analgesic prescribing amongst people with OUD. Existing evidence suggests that such prescribing is associated with a higher risk of suicidality, while the use of OAT together with opioid analgesics in this population may be protective against fatal overdose. Further observational and trial research is needed to clarify the benefits and harms of opioid analgesics for CNCP patients with OUD.

背景:阿片类药物使用障碍(OUD)在北美是一个日益严重的公共卫生问题,通常与慢性非癌性疼痛(CNCP)共存。管理这两种情况带来了独特的挑战,突出表明需要证据来指导决策。目的:本研究旨在进行系统综述,总结阿片类镇痛药单独或联合阿片类激动剂治疗(OAT)对OUD患者或OUD病史患者CNCP的疗效、有效性和安全性的证据。方法:我们检索MEDLINE、Embase、PsycINFO、CINAHL和AMED,检索从成立到2023年7月的随机研究,检索到2025年1月的非随机研究,这些研究探讨了阿片类药物对慢性疼痛患者和当前或既往OUD患者的疗效、有效性和安全性。我们评估了纳入研究的偏倚风险,使用GRADE方法评估了证据质量,并提供了治疗效果的叙述性总结。结果:我们的搜索确定了15,988个独特的引用,其中6个观察性研究被认为有资格为安全性结果提供审查,而没有观察性研究或随机对照试验符合疗效或有效性结果的资格标准。接受长期阿片类镇痛药的CNCP OUD患者的自杀可能性是未接受OUD患者的两倍(绝对风险增加:127;95%置信区间:在1000名参与者中,有自杀倾向的参与者多出36至249人;中等确定性证据)。与单独使用阿片类镇痛药相比,同时使用阿片类镇痛药和OAT的CNCP和OUD患者发生致命性阿片类药物过量的风险可能会降低(绝对风险降低:60;95%可信区间:1000名参与者中死亡人数减少18至94人;低确定性证据)。结论:在OUD患者中,关于阿片类镇痛药处方的实践和政策缺乏证据。现有证据表明,这种处方与较高的自杀风险有关,而在这一人群中,OAT与阿片类镇痛药一起使用可能对致命的过量服用有保护作用。需要进一步的观察和试验研究来阐明阿片类镇痛药对CNCP合并OUD患者的利弊。
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引用次数: 0
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Canadian Journal of Pain-Revue Canadienne de la Douleur
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