Pub Date : 2024-02-26eCollection Date: 2024-01-01DOI: 10.1080/24740527.2023.2284815
E Lamoureux, M G Pagé
{"title":"The Importance of Good Measurement: Development and Validation of a Measure of Disordered Eating Among Adults with Chronic Pain.","authors":"E Lamoureux, M G Pagé","doi":"10.1080/24740527.2023.2284815","DOIUrl":"10.1080/24740527.2023.2284815","url":null,"abstract":"","PeriodicalId":53214,"journal":{"name":"Canadian Journal of Pain-Revue Canadienne de la Douleur","volume":"8 1","pages":"2284815"},"PeriodicalIF":2.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10900263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-29eCollection Date: 2024-01-01DOI: 10.1080/24740527.2024.2310806
P Maxwell Slepian
{"title":"Can we use the tools we already have to help patients in need? Evaluating practice-based evidence of analgesic effects from intermittent theta burst stimulation for treatment of depression.","authors":"P Maxwell Slepian","doi":"10.1080/24740527.2024.2310806","DOIUrl":"https://doi.org/10.1080/24740527.2024.2310806","url":null,"abstract":"","PeriodicalId":53214,"journal":{"name":"Canadian Journal of Pain-Revue Canadienne de la Douleur","volume":"8 1","pages":"2310806"},"PeriodicalIF":2.4,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10950276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140177717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Future Is Bright: Highlighting Trainee Contributions to the Canadian Journal of Pain.","authors":"Hance Clarke, Mariana Bueno, Erika Harding, Tuan Trang, Jason J McDougall","doi":"10.1080/24740527.2023.2287032","DOIUrl":"10.1080/24740527.2023.2287032","url":null,"abstract":"","PeriodicalId":53214,"journal":{"name":"Canadian Journal of Pain-Revue Canadienne de la Douleur","volume":"7 2","pages":"2287032"},"PeriodicalIF":2.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10795778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139492964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-28eCollection Date: 2024-01-01DOI: 10.1080/24740527.2023.2288888
Amy L Burton, Imogen O'Loughlin, Kris Rogers, Toby R O Newton-John
Background: Chronic pain and higher body weight frequently co-occur. This common comorbidity is thought to be mediated by the use of comfort eating as a strategy for managing both the physical and psychological pain and discomfort associated with flare-ups of chronic pain. Valid and reliable assessment tools are needed to inform the development of effective treatments.
Aims: This study aimed to assess the psychometric properties of a new brief measure of pain-induced comfort eating in chronic pain, the Pain-Induced Comfort Eating Scale (PICES).
Methods: A sample of 166 patients with chronic pain completed an online test battery including the PICES along with measures of chronic pain and pain-related symptoms, disordered eating, and related psychological factors.
Results: Results of exploratory factor analysis revealed a single-factor model for the four-item PICES. Further, the PICES demonstrated evidence of good internal consistency as well as convergent validity with demonstrated correlations with related measures. The results of this study also revealed that comfort eating in chronic pain appears to be related to psychological distress; the PICES correlated more strongly with measures assessing mood and psychological distress compared to interference/intensity of physical pain itself. Scores on the PICES also correlated strongly with measures of uncontrolled and emotional eating.
Conclusions: Overall, our results indicate that the PICES provides a valid and useful brief measure of comfort eating in chronic pain that might be useful to inform treatments targeting the comorbid disordered eating practices that can lead to higher body weights in patients with chronic pain.
{"title":"Development and validation of the Pain-Induced Comfort Eating Scale in a chronic pain sample.","authors":"Amy L Burton, Imogen O'Loughlin, Kris Rogers, Toby R O Newton-John","doi":"10.1080/24740527.2023.2288888","DOIUrl":"https://doi.org/10.1080/24740527.2023.2288888","url":null,"abstract":"<p><strong>Background: </strong>Chronic pain and higher body weight frequently co-occur. This common comorbidity is thought to be mediated by the use of comfort eating as a strategy for managing both the physical and psychological pain and discomfort associated with flare-ups of chronic pain. Valid and reliable assessment tools are needed to inform the development of effective treatments.</p><p><strong>Aims: </strong>This study aimed to assess the psychometric properties of a new brief measure of pain-induced comfort eating in chronic pain, the Pain-Induced Comfort Eating Scale (PICES).</p><p><strong>Methods: </strong>A sample of 166 patients with chronic pain completed an online test battery including the PICES along with measures of chronic pain and pain-related symptoms, disordered eating, and related psychological factors.</p><p><strong>Results: </strong>Results of exploratory factor analysis revealed a single-factor model for the four-item PICES. Further, the PICES demonstrated evidence of good internal consistency as well as convergent validity with demonstrated correlations with related measures. The results of this study also revealed that comfort eating in chronic pain appears to be related to psychological distress; the PICES correlated more strongly with measures assessing mood and psychological distress compared to interference/intensity of physical pain itself. Scores on the PICES also correlated strongly with measures of uncontrolled and emotional eating.</p><p><strong>Conclusions: </strong>Overall, our results indicate that the PICES provides a valid and useful brief measure of comfort eating in chronic pain that might be useful to inform treatments targeting the comorbid disordered eating practices that can lead to higher body weights in patients with chronic pain.</p>","PeriodicalId":53214,"journal":{"name":"Canadian Journal of Pain-Revue Canadienne de la Douleur","volume":"8 1","pages":"2288888"},"PeriodicalIF":2.4,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11042059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140854400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Chronic pain is a costly and incapacitating condition, with a projected global prevalence of 20%. In South Africa, almost one in five adults experience chronic pain. The aim of this study was to assess the prevalence of chronic pain and the association between chronic pain intensity and the interference of pain with life domains in patients attending a primary health care center.
Methods: We conducted a cross-sectional quantitative study on a sample of 331 patients at Soshanguve Community Health Centre. The data were collected using the Wisconsin Brief Pain Questionnaire, a validated scale for measuring pain.
Results: The mean age of participants was 51.6 years (SD = ±15.15, range = 18-86). The median age was 48 years (interquartile range = 40-64). The prevalence of chronic pain was 21.5% (95% confidence interval [CI] 17.0-25.9). Approximately 58% of participants were female, and female patients were affected more frequently than male patients. Chronic pain was observed to be 11.1% more prevalent in females than in males. Chronic pain mildly impacted general activity in 33.8% of patients (95% CI 23.9-45.4), mood in 42.3% (95% CI 31.4-53.8), walking ability in 29.6% (95% CI 20.2-41.0), relationships in 47.9% (95% CI 36.7-59.3), sleep in 31.0% (95% CI 21.4-42.5), enjoyment of life in 39.4% (95% CI 28.9-51.1), and normal working ability in 25.3% (95% CI 16.7-36.6).
Conclusions: Findings from this study show that among patients who attended the primary health care clinic, chronic pain was highly prevalent and interfered with their life domains. The intensity of pain was high in a significant proportion of patients. These findings provide invaluable information needed for the improvement of resources at the primary care level to comprehensively evaluate pain in our communities.
简介慢性疼痛是一种代价高昂且使人丧失工作能力的疾病,预计全球发病率为 20%。在南非,几乎每五个成年人中就有一人患有慢性疼痛。本研究的目的是评估慢性疼痛的患病率以及慢性疼痛强度与疼痛对初级保健中心患者生活领域的干扰之间的关联:我们在 Soshanguve 社区医疗中心对 331 名患者样本进行了横断面定量研究。数据采用威斯康星州简短疼痛问卷收集,该问卷是一种经过验证的疼痛测量量表:参与者的平均年龄为 51.6 岁(SD = ±15.15,范围 = 18-86)。年龄中位数为 48 岁(四分位数间距 = 40-64)。慢性疼痛患病率为 21.5%(95% 置信区间 [CI] 17.0-25.9)。约 58% 的参与者为女性,女性患者的患病率高于男性患者。据观察,女性慢性疼痛的发病率比男性高出 11.1%。9%(95% CI 36.7-59.3)、睡眠31.0%(95% CI 21.4-42.5)、生活乐趣39.4%(95% CI 28.9-51.1)、正常工作能力25.3%(95% CI 16.7-36.6):研究结果表明,在初级保健诊所就诊的患者中,慢性疼痛的发病率很高,并干扰了他们的生活领域。相当一部分患者的疼痛强度很高。这些发现提供了宝贵的信息,有助于改善基层医疗机构的资源,全面评估我们社区的疼痛状况。
{"title":"Chronic pain: The prevalence of chronic pain in patients attending Soshanguve Community Health Centre.","authors":"Funeka Faith Pandelani, Suzan Louisa Nnanile Nyalunga, Thanyani Pandelani","doi":"10.1080/24740527.2023.2284152","DOIUrl":"10.1080/24740527.2023.2284152","url":null,"abstract":"<p><strong>Introduction: </strong>Chronic pain is a costly and incapacitating condition, with a projected global prevalence of 20%. In South Africa, almost one in five adults experience chronic pain. The aim of this study was to assess the prevalence of chronic pain and the association between chronic pain intensity and the interference of pain with life domains in patients attending a primary health care center.</p><p><strong>Methods: </strong>We conducted a cross-sectional quantitative study on a sample of 331 patients at Soshanguve Community Health Centre. The data were collected using the Wisconsin Brief Pain Questionnaire, a validated scale for measuring pain.</p><p><strong>Results: </strong>The mean age of participants was 51.6 years (SD = ±15.15, range = 18-86). The median age was 48 years (interquartile range = 40-64). The prevalence of chronic pain was 21.5% (95% confidence interval [CI] 17.0-25.9). Approximately 58% of participants were female, and female patients were affected more frequently than male patients. Chronic pain was observed to be 11.1% more prevalent in females than in males. Chronic pain mildly impacted general activity in 33.8% of patients (95% CI 23.9-45.4), mood in 42.3% (95% CI 31.4-53.8), walking ability in 29.6% (95% CI 20.2-41.0), relationships in 47.9% (95% CI 36.7-59.3), sleep in 31.0% (95% CI 21.4-42.5), enjoyment of life in 39.4% (95% CI 28.9-51.1), and normal working ability in 25.3% (95% CI 16.7-36.6).</p><p><strong>Conclusions: </strong>Findings from this study show that among patients who attended the primary health care clinic, chronic pain was highly prevalent and interfered with their life domains. The intensity of pain was high in a significant proportion of patients. These findings provide invaluable information needed for the improvement of resources at the primary care level to comprehensively evaluate pain in our communities.</p>","PeriodicalId":53214,"journal":{"name":"Canadian Journal of Pain-Revue Canadienne de la Douleur","volume":"8 1","pages":"2284152"},"PeriodicalIF":2.0,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11195477/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141447593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-10DOI: 10.1080/24740527.2023.2255070
Winfried Häuser, Mary-Ann Fitzcharles
{"title":"Adherence to Clinical Guidelines for Fibromyalgia: Help or Hindrance?","authors":"Winfried Häuser, Mary-Ann Fitzcharles","doi":"10.1080/24740527.2023.2255070","DOIUrl":"https://doi.org/10.1080/24740527.2023.2255070","url":null,"abstract":"","PeriodicalId":53214,"journal":{"name":"Canadian Journal of Pain-Revue Canadienne de la Douleur","volume":"60 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135092992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-03DOI: 10.1080/24740527.2023.2272999
Caleb Tackey, P. Maxwell Slepian, Hance Clarke, Nimish Mittal
Post-viral pain syndrome, also known as post-viral syndrome (PVS), is a complex condition characterized by persistent pain, fatigue, musculoskeletal pain, neuropathic pain, neurocognitive difficulties, and sleep disturbances1,2 that can occur after an individual has recovered from a viral infection. Much remains unknown regarding the pathophysiology of post-viral syndromes and few studies have provided a comprehensive summary of the condition, agents that cause it, and successful treatment modalities. With the COVID-19 pandemic continuing to affect millions of people worldwide, the need for understanding the etiology of post-viral illness and how to help individuals cope with the sequalae is paramount.2 This narrative review provides a summary of the sequelae of post-viral syndromes, viral agents that cause it, the pathophysiology, treatment, and future considerations for research and targeted therapies.
{"title":"Post Viral Pain, Fatigue, and Sleep Disturbance Syndromes: Current knowledge and Future Directions","authors":"Caleb Tackey, P. Maxwell Slepian, Hance Clarke, Nimish Mittal","doi":"10.1080/24740527.2023.2272999","DOIUrl":"https://doi.org/10.1080/24740527.2023.2272999","url":null,"abstract":"Post-viral pain syndrome, also known as post-viral syndrome (PVS), is a complex condition characterized by persistent pain, fatigue, musculoskeletal pain, neuropathic pain, neurocognitive difficulties, and sleep disturbances1,2 that can occur after an individual has recovered from a viral infection. Much remains unknown regarding the pathophysiology of post-viral syndromes and few studies have provided a comprehensive summary of the condition, agents that cause it, and successful treatment modalities. With the COVID-19 pandemic continuing to affect millions of people worldwide, the need for understanding the etiology of post-viral illness and how to help individuals cope with the sequalae is paramount.2 This narrative review provides a summary of the sequelae of post-viral syndromes, viral agents that cause it, the pathophysiology, treatment, and future considerations for research and targeted therapies.","PeriodicalId":53214,"journal":{"name":"Canadian Journal of Pain-Revue Canadienne de la Douleur","volume":"46 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135818147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-06DOI: 10.1080/24740527.2023.2266751
Rasheeda Darville-Beneby, Anna M. Lomanowska, Hai Chuan Yu, Parker Jobin, Brittany N. Rosenbloom, Gretchen Gabriel, Helena Daudt, Michael Negraeff, Tania Di Renna, Maria Hudspith, Hance Clarke
Background Recent studies show preoperative education can positively impact postoperative recovery, improving postoperative pain management and patient satisfaction. Gaps in preoperative education regarding postoperative pain and opioid use may lead to increased patient anxiety and persistent postoperative opioid use.
{"title":"The impact of preoperative patient education on postoperative pain, opioid use, and psychological outcomes: A narrative review","authors":"Rasheeda Darville-Beneby, Anna M. Lomanowska, Hai Chuan Yu, Parker Jobin, Brittany N. Rosenbloom, Gretchen Gabriel, Helena Daudt, Michael Negraeff, Tania Di Renna, Maria Hudspith, Hance Clarke","doi":"10.1080/24740527.2023.2266751","DOIUrl":"https://doi.org/10.1080/24740527.2023.2266751","url":null,"abstract":"Background Recent studies show preoperative education can positively impact postoperative recovery, improving postoperative pain management and patient satisfaction. Gaps in preoperative education regarding postoperative pain and opioid use may lead to increased patient anxiety and persistent postoperative opioid use.","PeriodicalId":53214,"journal":{"name":"Canadian Journal of Pain-Revue Canadienne de la Douleur","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135351965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-06DOI: 10.1080/24740527.2023.2266738
Sherif M. Elsaraj, Mervyn Gornitsky, Richard Hovey, Firoozeh Samim, Zovinar Der Khatchadourian, Ana Velly
Insomnia and excessive daytime sleepiness, a surrogate marker of obstructive sleep apnea, are common sleep-related conditions among painful temporomandibular disorders (TMD) subjects. Obstructive sleep apnea was found to increase the risk of chronic painful TMD. This prospective cohort study aims to determine the contribution of insomnia and excessive daytime sleepiness (ESS/OSA) on acute to chronic painful TMD transition as well as its persistence when chronic pain is defined by: (i) duration (> 3 months), and (ii) dysfunction (Graded Chronic Pain Scale [GCPS II-IV]). From 456 subjects recruited between 2015 to 2021, through four locations in Canada, 378 completed the follow-up. A diagnosis was obtained using the Research Diagnostic Criteria or the Diagnostic Criteria for Temporomandibular Disorders. Insomnia was assessed with the Insomnia Severity Scale (ISS), and excessive daytime sleepiness was measured using the Epworth Sleepiness Scale (ESS/OSA), both at baseline. Subjects completed the GCPS form at baseline and 3-month follow-up. Borderline associations were found between ESS/OSA and the transition or persistence of chronic painful TMD when chronic pain was defined by pain duration (RR adjusted_duration = 1.11, P = 0.07) and dysfunction (RRadjusted_dysfunction =1.40, P = 0.051). Furthermore, ESS/OSA was specifically associated with persistent painful TMD when chronic pain was defined by pain duration (RR = 1.13, 95%CI: 1.00-1.26, P = 0.04). Insomnia was not related to the study outcomes (RRadjusted_duration = 0.94, P = 0.27, RRadjusted_dysfunction =1.00, P = 0.99). Results indicate that ESS/OSA contrary to insomnia predicted the persistence of chronic painful TMD at a 3-month follow-up.
失眠和白天过度嗜睡是阻塞性睡眠呼吸暂停的替代标志,是疼痛性颞下颌疾病(TMD)患者中常见的睡眠相关疾病。发现阻塞性睡眠呼吸暂停会增加慢性疼痛性TMD的风险。这项前瞻性队列研究旨在确定失眠和白天过度嗜睡(ESS/OSA)对急性到慢性疼痛性TMD转变的贡献,以及慢性疼痛的持久性,慢性疼痛的定义是:(i)持续时间(> 3个月),(ii)功能障碍(分级慢性疼痛量表[GCPS ii - iv])。2015年至2021年间,在加拿大的四个地点招募了456名受试者,其中378人完成了随访。使用研究诊断标准或颞下颌疾病诊断标准进行诊断。采用失眠严重程度量表(ISS)评估失眠症,使用Epworth嗜睡量表(ESS/OSA)测量白天过度嗜睡,两者均为基线。受试者在基线和3个月随访时完成GCPS表格。当慢性疼痛被定义为疼痛持续时间(RR adjusted_duration = 1.11, P = 0.07)和功能障碍(RRadjusted_dysfunction =1.40, P = 0.051)时,发现ESS/OSA与慢性疼痛性TMD的转变或持续存在边缘性关联。此外,当以疼痛持续时间定义慢性疼痛时,ESS/OSA与持续性疼痛性TMD特异性相关(RR = 1.13, 95%CI: 1.00-1.26, P = 0.04)。失眠与研究结果无关(RRadjusted_duration = 0.94, P = 0.27, RRadjusted_dysfunction =1.00, P = 0.99)。结果表明,在3个月的随访中,ESS/OSA与失眠相反,可预测慢性疼痛性TMD的持续存在。
{"title":"The contribution of insomnia and obstructive sleep apnea on the transition from acute to chronic painful temporomandibular disorders, and its persistence: a prospective 3-month cohort study","authors":"Sherif M. Elsaraj, Mervyn Gornitsky, Richard Hovey, Firoozeh Samim, Zovinar Der Khatchadourian, Ana Velly","doi":"10.1080/24740527.2023.2266738","DOIUrl":"https://doi.org/10.1080/24740527.2023.2266738","url":null,"abstract":"Insomnia and excessive daytime sleepiness, a surrogate marker of obstructive sleep apnea, are common sleep-related conditions among painful temporomandibular disorders (TMD) subjects. Obstructive sleep apnea was found to increase the risk of chronic painful TMD. This prospective cohort study aims to determine the contribution of insomnia and excessive daytime sleepiness (ESS/OSA) on acute to chronic painful TMD transition as well as its persistence when chronic pain is defined by: (i) duration (> 3 months), and (ii) dysfunction (Graded Chronic Pain Scale [GCPS II-IV]). From 456 subjects recruited between 2015 to 2021, through four locations in Canada, 378 completed the follow-up. A diagnosis was obtained using the Research Diagnostic Criteria or the Diagnostic Criteria for Temporomandibular Disorders. Insomnia was assessed with the Insomnia Severity Scale (ISS), and excessive daytime sleepiness was measured using the Epworth Sleepiness Scale (ESS/OSA), both at baseline. Subjects completed the GCPS form at baseline and 3-month follow-up. Borderline associations were found between ESS/OSA and the transition or persistence of chronic painful TMD when chronic pain was defined by pain duration (RR adjusted_duration = 1.11, P = 0.07) and dysfunction (RRadjusted_dysfunction =1.40, P = 0.051). Furthermore, ESS/OSA was specifically associated with persistent painful TMD when chronic pain was defined by pain duration (RR = 1.13, 95%CI: 1.00-1.26, P = 0.04). Insomnia was not related to the study outcomes (RRadjusted_duration = 0.94, P = 0.27, RRadjusted_dysfunction =1.00, P = 0.99). Results indicate that ESS/OSA contrary to insomnia predicted the persistence of chronic painful TMD at a 3-month follow-up.","PeriodicalId":53214,"journal":{"name":"Canadian Journal of Pain-Revue Canadienne de la Douleur","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135351520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-29DOI: 10.1080/24740527.2023.2264895
Jessica Parnell, Newton Martin, Annemarie Dedek, Christopher Rudyk, Jeffrey Landrigan, Justin Bellavance, Simon Vanderloo, Eve C. Tsai, Michael E. Hildebrand
Background Preclinical and clinical evidence suggests that cannabis has potential analgesic properties. However, cannabinoid receptor expression and localization within spinal cord pain processing circuits remains to be characterized across sex and species.
{"title":"Cannabinoid CB1 receptor expression and localization in the dorsal horn of male and female rat and human spinal cord","authors":"Jessica Parnell, Newton Martin, Annemarie Dedek, Christopher Rudyk, Jeffrey Landrigan, Justin Bellavance, Simon Vanderloo, Eve C. Tsai, Michael E. Hildebrand","doi":"10.1080/24740527.2023.2264895","DOIUrl":"https://doi.org/10.1080/24740527.2023.2264895","url":null,"abstract":"Background Preclinical and clinical evidence suggests that cannabis has potential analgesic properties. However, cannabinoid receptor expression and localization within spinal cord pain processing circuits remains to be characterized across sex and species.","PeriodicalId":53214,"journal":{"name":"Canadian Journal of Pain-Revue Canadienne de la Douleur","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135200039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}