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Comparison of opioid use among long-term care residents in Ontario and Alberta, Canada: A multi-jurisdictional, repeated cross-sectional study. 加拿大安大略省和阿尔伯塔省长期护理居民中阿片类药物使用的比较:一项多司法管辖区的重复横断面研究。
IF 2 Q3 CLINICAL NEUROLOGY Pub Date : 2025-07-10 eCollection Date: 2025-01-01 DOI: 10.1080/24740527.2025.2518151
Colleen J Maxwell, Michael A Campitelli, Andrea Gruneir, Andrea Iaboni, Laura C Maclagan, David B Hogan, Erik Youngson, Xueyi Chen, Zhiyin Li, Susan E Bronskill

Background: Exploring regional variation in opioid use for pain among long-term care (LTC) residents may help identify modifiable factors associated with suboptimal prescribing practices.

Aims: We aimed to compare recent trends in prevalent opioid use and higher risk prescribing among LTC residents in Ontario and Alberta, and to examine variation in opioid trends across resident subgroups within each province.

Methods: Utilizing comparable linked clinical and health administrative databases for LTC residents (aged >65) in each province, we examined trends in monthly use of any opioid, specific drug types and formulations, high daily doses (≥90 Morphine Equivalents), and concurrent use with a benzodiazepine or gabapentinoid. Prevalence ratios comparing change in opioid measures, overall and across resident subgroups, from the first (March 2015) to last study (March 2022) months were estimated using age-sex adjusted log-binomial regression models.

Results: Opioid prevalence (any, select types, long-acting formulations, high daily doses) was consistently higher among Ontario residents whereas concurrent use with a benzodiazepine or gabapentinoid was higher among Alberta residents. Overall use remained stable in Ontario but increased by 23% in Alberta LTC. In both provinces, there were significant decreases in higher risk opioid prescribing over time, including concurrent use with benzodiazepines, but also significant increases in the concurrent use with gabapentinoids and tramadol use (Alberta only).

Conclusions: Although both provinces showed trends toward more appropriate opioid use in LTC, the factors driving observed provincial differences in opioid prescribing and the rise in concurrent opioid and gabapentinoid use among residents, warrant further investigation.

背景:探索长期护理(LTC)居民阿片类药物用于疼痛的区域差异可能有助于确定与次优处方实践相关的可修改因素。目的:我们旨在比较安大略省和阿尔伯塔省LTC居民中普遍使用阿片类药物和高风险处方的最新趋势,并检查每个省居民亚组中阿片类药物趋势的变化。方法:利用各省LTC居民(年龄在65岁至65岁之间)的可比临床和卫生管理数据库,我们检查了每月使用任何阿片类药物、特定药物类型和配方、高日剂量(≥90吗啡当量)以及同时使用苯二氮卓类药物或加巴喷丁类药物的趋势。从第一个月(2015年3月)到最后一个研究月(2022年3月),使用年龄-性别调整的对数二项回归模型估计了总体和跨居民亚组阿片类药物测量变化的患病率。结果:阿片类药物患病率(任何,选择类型,长效制剂,高日剂量)在安大略省居民中一直较高,而同时使用苯二氮卓类药物或加巴喷丁类药物在阿尔伯塔省居民中较高。安大略省的总体使用量保持稳定,但阿尔伯塔省LTC的使用量增加了23%。在这两个省,随着时间的推移,高风险的阿片类药物处方显著减少,包括同时使用苯二氮卓类药物,但同时使用加巴喷丁类药物和曲马多的情况也显著增加(仅艾伯塔省)。结论:尽管两省在慢性阻塞性肺疾病中都表现出更合理使用阿片类药物的趋势,但导致阿片类药物处方和居民中阿片类药物和加巴喷丁类药物同时使用增加的因素存在差异,值得进一步调查。
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引用次数: 0
Highlighting the success of the Canadian Journal of Pain's inaugural Editorial Review Mentorship Program. 强调加拿大疼痛杂志首届编辑评审指导计划的成功。
IF 2 Q3 CLINICAL NEUROLOGY Pub Date : 2025-07-10 eCollection Date: 2025-01-01 DOI: 10.1080/24740527.2025.2518148
M G Pagé, J Katz
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引用次数: 0
Development of a pain management competency assessment for physiotherapy students: Integrating simulation and written assessments. 物理治疗学生疼痛管理能力评估的发展:整合模拟和书面评估。
IF 2 Q3 CLINICAL NEUROLOGY Pub Date : 2025-07-08 eCollection Date: 2025-01-01 DOI: 10.1080/24740527.2025.2512728
Nathan Augeard, Jordan Miller, Geoff Bostick, Christina St-Onge, Yannick Tousignant-Laflamme, Anne Hudon, David Walton, Lesley Singer, Lynn Cooper, André Bussières, Aliki Thomas, Kadija Perreault, Susan Tupper, Lisa C Carlesso, Peter Stilwell, Fatima Amari, Kevin Varette, Claire Ashton-James, Timothy H Wideman

Introduction: Chronic pain is a global challenge resulting in substantial healthcare costs. Despite its prevalence, gaps in pain management education persist across health professions education programs. Developing an assessment to evaluate student competency in pain management is essential to identify and address the potential impact of these disparities on learning outcomes. This study describes the development and initial evaluation of the Pain Education in Physiotherapy (PEP) competency assessment, aimed at assessing student level of competency in pain management across entrylevel physiotherapy (PT) programs.

Methods: The assessment was developed using the DeVellis process, incorporating integrated knowledge translation principles and ongoing partner engagement. A steering group guided the creation of case-based multiple choice questions (MCQs) and simulation-based stations to assess competencies for pain management at different levels of Miller's Pyramid. Initial evidence supporting the validity argument was gathered from PT students in their final semester of education (n = 146 for MCQs; n = 53 for simulations).

Results: Twenty-eight MCQ items and three simulation-based stations were selected. The MCQ component showed moderate internal consistency (α = 0.65), and the simulation-based assessments demonstrated moderate internal consistency (α = 0.63) with good interrater reliability (ICC2,1 range: 0.73-0.86).

Discussion: The PEP assessment incorporates case-based MCQs and simulation-based assessment stations to address critical interpersonal skills such as communication and empathy, often overlooked in traditional written assessments. This approach fills gaps in pain management education and provides a more comprehensive assessment tailored to PT needs.

Conclusion: This assessment represents an important advancement in the assessment of pain management competencies. Its rigorous development process, partner engagement, and promising initial evaluation underscore its potential to identify gaps in pain education and help improve outcomes related to PT education.

慢性疼痛是一个全球性的挑战,导致大量的医疗保健费用。尽管疼痛管理教育普遍存在,但在卫生专业教育项目中,疼痛管理教育存在差距。开发一种评估方法来评估学生在疼痛管理方面的能力,对于识别和解决这些差异对学习结果的潜在影响至关重要。本研究描述了物理治疗疼痛教育(PEP)能力评估的发展和初步评估,旨在评估学生在入门级物理治疗(PT)项目中疼痛管理的能力水平。方法:评估采用devlis过程,结合集成知识翻译原则和持续的合作伙伴参与。一个指导小组指导了基于案例的多项选择题(mcq)和基于模拟的工作站的创建,以评估米勒金字塔不同层次的疼痛管理能力。支持效度论点的初步证据是从他们教育的最后一个学期的PT学生中收集的(n = 146对于mcq;N = 53(模拟)。结果:选取了28个MCQ项目和3个模拟站点。MCQ成分具有中等的内部一致性(α = 0.65),基于模拟的评估具有中等的内部一致性(α = 0.63),具有良好的内部信度(ICC2,1范围:0.73-0.86)。讨论:PEP评估结合了基于案例的mcq和基于模拟的评估站,以解决在传统书面评估中经常被忽视的关键人际交往技能,如沟通和同理心。这种方法填补了疼痛管理教育的空白,并提供了针对PT需求的更全面的评估。结论:该评估代表了疼痛管理能力评估的重要进展。其严格的开发过程、合作伙伴的参与和有希望的初步评估强调了其识别疼痛教育差距的潜力,并有助于改善与PT教育相关的结果。
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引用次数: 0
Associations between military sexual trauma and chronic pain in men and women active military members and veterans. 军人性创伤与慢性疼痛在男女现役军人和退伍军人中的关系。
IF 2 Q3 CLINICAL NEUROLOGY Pub Date : 2025-05-28 eCollection Date: 2025-01-01 DOI: 10.1080/24740527.2025.2494582
Joy C MacDermid, Dimitra V Pouliopoulou, David M Walton, Angel Kibble, Pavlos Bobos

Introduction: We evaluated gendered risks and the associations between demographics, anxiety, and depressive symptoms, military sexual trauma (MST), and severe pain in Canadian military personnel and veterans.

Methods: A cross-sectional sample of 328 veterans and military members with chronic pain completed confidential surveys, including demographics, disability, pain location, and intensity, as well as a Patient Health Questionnaire (PHQ-4). We evaluated gendered exposures (rates, odds ratios), associations between MST and severe pain (logistic regression), and associations with pain severity and PHQ-4 (linear regression), adjusting for age, race, and education.

Results: We found high levels of chronic pain and disability for women and men (6.8 or 6.9/10), PHQ-4 scores (6.6 or 6.2/12), and SANE scores (11% or 10%). Women reported higher exposure to MST (e.g. 69% for sexual harassment, 76% for emotional abuse) than men (8% and 13%). Odds of severe pain were not gendered (OR = 1.05). Physical abuse (β = 1.09, p = .030) and gender discrimination (β = 1.10, p = .033) were associated with higher PHQ-4 scores. Sexual harassment was not independently associated (OR = 1.57, p = .354) with chronic pain, but was associated with increased anxiety and depressive symptoms (β = 1.06, p = .016). Higher PHQ-4 scores were significantly associated with higher pain scores (β = 0.18, p < .001).

Conclusions: MST exposures are much more common among women, but the associations of MST with severe pain and PHQ-4 scores are similar across genders. Differences in operational trauma and occupational trauma may influence occupational stress injuries and chronic pain.

简介:我们评估了加拿大军人和退伍军人的性别风险以及人口统计学、焦虑和抑郁症状、军事性创伤(MST)和严重疼痛之间的关系。方法:对328名患有慢性疼痛的退伍军人和军人进行横断面调查,包括人口统计、残疾、疼痛部位和强度,以及患者健康问卷(PHQ-4)。我们评估了性别暴露(比率、优势比)、MST与剧烈疼痛之间的关联(逻辑回归)、疼痛严重程度和PHQ-4之间的关联(线性回归),并调整了年龄、种族和教育程度。结果:我们发现女性和男性的慢性疼痛和残疾水平较高(6.8或6.9/10),PHQ-4评分(6.6或6.2/12)和SANE评分(11%或10%)。据报告,女性比男性(8%和13%)更容易遭受MST(例如,性骚扰占69%,精神虐待占76%)。剧烈疼痛的发生率没有性别区分(OR = 1.05)。身体虐待(β = 1.09, p = 0.030)和性别歧视(β = 1.10, p = 0.033)与PHQ-4得分较高相关。性骚扰与慢性疼痛无关(OR = 1.57, p = .354),但与焦虑和抑郁症状增加相关(β = 1.06, p = .016)。PHQ-4评分越高,疼痛评分越高(β = 0.18, p < 0.001)。结论:MST暴露在女性中更为常见,但MST与严重疼痛和PHQ-4评分的关系在性别之间相似。手术创伤和职业创伤的差异可能影响职业性应激损伤和慢性疼痛。
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引用次数: 0
Racial/ethnic disparities in pain among Canadian adults. 加拿大成年人疼痛的种族差异。
IF 2.1 Q3 CLINICAL NEUROLOGY Pub Date : 2025-05-19 eCollection Date: 2024-01-01 DOI: 10.1080/24740527.2025.2496683
Merita Limani, Anna Zajacova

Background: Understanding pain disparities is critical for fostering health equity and guiding effective health policies. However, little is known about racial/ethnic disparities in pain among adults in Canada.

Aims: We provide a comprehensive analysis of racial/ethnic disparities in pain among Canadian adults, focusing on two dimensions of pain - frequent pain and interfering pain.

Methods: We use two-wave cross-sectional data collected in 2020 and 2022 from a representative sample of 4,637 adults aged 18 and older residing in Canada. We calculate the prevalence of pain among White, Black, East/Southeast Asian, South Asian, Indigenous, Multiracial, and "Other" groups and estimate relative differences adjusted for key covariates in a multivariable framework.

Results: The data reveal large and statistically significant pain disparities; specific patterns, however, vary across the two pain outcomes and by gender. Indigenous Canadians have relatively high prevalence of both frequent pain (38.4%) and interfering pain (27.8%), while East/Southeast Asian Canadians have the lowest prevalence of both (8.2% and 14.4%, respectively). Black Canadians have a relatively low prevalence of frequent pain (16.9%) but a very high prevalence of interfering pain (27.8%). Covariates are associated with pain levels but less so with the racial/ethnic patterns in pain.

Conclusions: Our analysis highlights substantial racial/ethnic disparities in pain prevalence among Canadian adults. Further research is essential to better understand the root causes of the observed disparities and ultimately improve the lives of Canadians living with pain.

背景:了解疼痛差异对于促进卫生公平和指导有效的卫生政策至关重要。然而,我们对加拿大成年人疼痛的种族差异知之甚少。目的:我们提供了一个全面的分析在加拿大成年人的疼痛种族/民族差异,重点在疼痛的两个维度-频繁疼痛和干扰性疼痛。方法:我们使用了2020年和2022年从居住在加拿大的4,637名18岁及以上成年人的代表性样本中收集的两波横断面数据。我们计算了白人、黑人、东亚/东南亚、南亚、土著、多种族和“其他”群体的疼痛患病率,并估计了在多变量框架中调整关键协变量后的相对差异。结果:数据显示疼痛差异大且具有统计学意义;然而,具体的模式因两种疼痛结果和性别而异。加拿大原住民的频繁疼痛(38.4%)和干扰性疼痛(27.8%)的患病率相对较高,而东亚/东南亚加拿大人的这两种患病率最低(分别为8.2%和14.4%)。加拿大黑人频繁疼痛的患病率相对较低(16.9%),但干扰性疼痛的患病率非常高(27.8%)。协变量与疼痛程度有关,但与疼痛的种族/民族模式关系不大。结论:我们的分析强调了加拿大成年人疼痛患病率的种族差异。为了更好地了解观察到的差异的根本原因,并最终改善患有疼痛的加拿大人的生活,进一步的研究是必不可少的。
{"title":"Racial/ethnic disparities in pain among Canadian adults.","authors":"Merita Limani, Anna Zajacova","doi":"10.1080/24740527.2025.2496683","DOIUrl":"10.1080/24740527.2025.2496683","url":null,"abstract":"<p><strong>Background: </strong>Understanding pain disparities is critical for fostering health equity and guiding effective health policies. However, little is known about racial/ethnic disparities in pain among adults in Canada.</p><p><strong>Aims: </strong>We provide a comprehensive analysis of racial/ethnic disparities in pain among Canadian adults, focusing on two dimensions of pain - frequent pain and interfering pain.</p><p><strong>Methods: </strong>We use two-wave cross-sectional data collected in 2020 and 2022 from a representative sample of 4,637 adults aged 18 and older residing in Canada. We calculate the prevalence of pain among White, Black, East/Southeast Asian, South Asian, Indigenous, Multiracial, and \"Other\" groups and estimate relative differences adjusted for key covariates in a multivariable framework.</p><p><strong>Results: </strong>The data reveal large and statistically significant pain disparities; specific patterns, however, vary across the two pain outcomes and by gender. Indigenous Canadians have relatively high prevalence of both frequent pain (38.4%) and interfering pain (27.8%), while East/Southeast Asian Canadians have the lowest prevalence of both (8.2% and 14.4%, respectively). Black Canadians have a relatively low prevalence of frequent pain (16.9%) but a very high prevalence of interfering pain (27.8%). Covariates are associated with pain levels but less so with the racial/ethnic patterns in pain.</p><p><strong>Conclusions: </strong>Our analysis highlights substantial racial/ethnic disparities in pain prevalence among Canadian adults. Further research is essential to better understand the root causes of the observed disparities and ultimately improve the lives of Canadians living with pain.</p>","PeriodicalId":53214,"journal":{"name":"Canadian Journal of Pain-Revue Canadienne de la Douleur","volume":"8 2","pages":"2496683"},"PeriodicalIF":2.1,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12091919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Meaning-making and coping in youth with chronic pain: A palliative and cultural perspective from the Philippines. 意义制造和应对青年与慢性疼痛:从菲律宾姑息和文化的角度来看。
IF 2 Q3 CLINICAL NEUROLOGY Pub Date : 2025-05-12 eCollection Date: 2025-01-01 DOI: 10.1080/24740527.2025.2496678
Jeff Clyde G Corpuz
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引用次数: 0
Initial evaluation of an intervention to address provider implicit bias in pediatric sickle cell disease pain care: A mixed methods pilot study. 解决儿科镰状细胞病疼痛护理中提供者内隐偏见的干预措施的初步评估:一项混合方法的试点研究。
IF 2 Q3 CLINICAL NEUROLOGY Pub Date : 2025-05-09 eCollection Date: 2024-01-01 DOI: 10.1080/24740527.2025.2486819
Siddika S Mulchan, Christopher B Theriault, Susan DiVietro, Mark D Litt, Emily O Wakefield, Javeed Sukhera, Paula Tanabe, Hannah R Thomas, Melissa Santos, William T Zempsky, Donna Boruchov, Adam T Hirsh

Background: Health care provider (HCP) implicit bias can impact health outcomes for youth with sickle cell disease (SCD).

Aims: : The aim of this study was to evaluate the feasibility, acceptability, and preliminary impact of an individuation and perspective-taking (IPT) intervention to decrease implicit bias and improve pain treatment clinical decision making in pediatric SCD HCPs.

Methods: This mixed methods pilot randomly assigned HCPs (N = 36) to an intervention (n = 17) or control condition (n = 19). Implicit and explicit bias measures were administered pretreatment and 3 months postintervention. Differences were analyzed using repeated measures analyses of variance. HCP ratings of virtual patient vignettes depicting Black and White youth with SCD or cancer pain were used to assess differential clinical decision making based on race and diagnosis and analyzed using hierarchical linear mixed model analysis. Focus groups with intervention participants were analyzed using thematic analysis.

Results: No significant differences in scores on bias measures across time, condition, or the Condition × Time interaction were found (all P < 0.05). Significant differences in HCP ratings were found between types of HCPs (P < 0.001), but no effects were attributable to condition, time, virtual patient race, or diagnosis. Ten themes were extracted regarding the intervention's format, structure, and content.

Conclusions: This study is the first to evaluate an IPT intervention in pediatric SCD HCPs. HCPs deemed the intervention feasible, acceptable, and impactful and suggested areas for improvement. Future research should refine the intervention to incorporate greater patient involvement and skills practice to improve health outcomes for this underserved population.

背景:卫生保健提供者(HCP)内隐偏见可以影响青少年镰状细胞病(SCD)的健康结果。目的:本研究的目的是评估个性化和换位思考(IPT)干预在儿童SCD HCPs中减少内隐偏倚和改善疼痛治疗临床决策的可行性、可接受性和初步影响。方法:该混合方法试验将36名医护人员随机分配到干预组(N = 17)或对照组(N = 19)。在干预前和干预后3个月分别进行内隐和外显偏倚测量。差异分析采用重复测量方差分析。描述患有SCD或癌性疼痛的黑人和白人青年的虚拟患者画像的HCP评分用于评估基于种族和诊断的差异临床决策,并使用分层线性混合模型分析进行分析。采用主题分析法对有干预参与者的焦点小组进行分析。结果:在时间、条件或条件×时间交互作用中,偏倚测量的得分无显著差异(均P < 0.05)。不同HCP类型间HCP评分存在显著差异(P < 0.001),但不受病情、时间、虚拟患者种族或诊断的影响。从干预的形式、结构和内容中提取了10个主题。结论:本研究首次对儿童SCD HCPs的IPT干预进行了评估。HCPs认为干预是可行的、可接受的、有效的,并提出了需要改进的地方。未来的研究应完善干预措施,纳入更多的患者参与和技能实践,以改善这一服务不足人群的健康结果。
{"title":"Initial evaluation of an intervention to address provider implicit bias in pediatric sickle cell disease pain care: A mixed methods pilot study.","authors":"Siddika S Mulchan, Christopher B Theriault, Susan DiVietro, Mark D Litt, Emily O Wakefield, Javeed Sukhera, Paula Tanabe, Hannah R Thomas, Melissa Santos, William T Zempsky, Donna Boruchov, Adam T Hirsh","doi":"10.1080/24740527.2025.2486819","DOIUrl":"https://doi.org/10.1080/24740527.2025.2486819","url":null,"abstract":"<p><strong>Background: </strong>Health care provider (HCP) implicit bias can impact health outcomes for youth with sickle cell disease (SCD).</p><p><strong>Aims: </strong>: The aim of this study was to evaluate the feasibility, acceptability, and preliminary impact of an individuation and perspective-taking (IPT) intervention to decrease implicit bias and improve pain treatment clinical decision making in pediatric SCD HCPs.</p><p><strong>Methods: </strong>This mixed methods pilot randomly assigned HCPs (<i>N</i> = 36) to an intervention (<i>n</i> = 17) or control condition (<i>n</i> = 19). Implicit and explicit bias measures were administered pretreatment and 3 months postintervention. Differences were analyzed using repeated measures analyses of variance. HCP ratings of virtual patient vignettes depicting Black and White youth with SCD or cancer pain were used to assess differential clinical decision making based on race and diagnosis and analyzed using hierarchical linear mixed model analysis. Focus groups with intervention participants were analyzed using thematic analysis.</p><p><strong>Results: </strong>No significant differences in scores on bias measures across time, condition, or the Condition × Time interaction were found (all <i>P</i> < 0.05). Significant differences in HCP ratings were found between types of HCPs (<i>P</i> < 0.001), but no effects were attributable to condition, time, virtual patient race, or diagnosis. Ten themes were extracted regarding the intervention's format, structure, and content.</p><p><strong>Conclusions: </strong>This study is the first to evaluate an IPT intervention in pediatric SCD HCPs. HCPs deemed the intervention feasible, acceptable, and impactful and suggested areas for improvement. Future research should refine the intervention to incorporate greater patient involvement and skills practice to improve health outcomes for this underserved population.</p>","PeriodicalId":53214,"journal":{"name":"Canadian Journal of Pain-Revue Canadienne de la Douleur","volume":"8 2","pages":"2486819"},"PeriodicalIF":2.0,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068330/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The pain funding gap: A database analysis of pain research funding in Canada from 2008-2023. 疼痛研究经费缺口:2008-2023年加拿大疼痛研究经费的数据库分析。
IF 2.1 Q3 CLINICAL NEUROLOGY Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.1080/24740527.2025.2486835
S S Abssy, R Bosma, S Miles, H Clarke, M Moayedi

Background: One in five Canadians experiences chronic pain, at a cost of $40.3 billion in 2019. Despite this significant burden, there are few effective treatments for pain. This gap has been recognized by Health Canada, which has put forth the Action Plan for Pain in Canada. Advancing our understanding of pain mechanisms and clinical trials to identify novel therapeutics are essential to address this treatment gap. However, it remains unknown whether the recommendations of the Action Plan have increased research investments.

Methods: We investigate research investments in pain by the Canadian Institutes of Health Research (CIHR) based on publicly available data. We performed a systematic database search focused on operating funds from competitions between 2008 and 2023 and tabulated pain funding as a proportion of total CIHR operational funds granted each year. Next, we examined the proportion of pain funding across CIHR institutes aggregated across funding years.

Results: We identified 20,126 operational grants, of which 459 were pain focused. The highest level of pain funding was 3.32% in 2019, and the average (SD) was 2.13% (0.70%). Funding was stagnant from 2008 to 2023 (R 2 = 0.10, P = 0.23). The Institute of Musculoskeletal Health and Arthritis allocated the largest proportion of funding to pain research (11.40%). Eight of the 13 institutes allocated less than 1% of their operating funds to pain research.

Interpretation: In sum, CIHR pain research funding does not match the socioeconomic burden posed by pain. We propose three action items to improve pain research funding and to ultimately relieve the burden of pain in Canada.

背景:五分之一的加拿大人患有慢性疼痛,2019年的成本为403亿美元。尽管这是一个巨大的负担,但几乎没有有效的治疗疼痛的方法。加拿大卫生部认识到这一差距,并提出了《加拿大疼痛问题行动计划》。推进我们对疼痛机制的理解和临床试验以确定新的治疗方法对于解决这一治疗差距至关重要。然而,目前尚不清楚行动计划的建议是否增加了研究投资。方法:我们根据公开数据调查加拿大卫生研究院(CIHR)在疼痛方面的研究投入。我们进行了系统的数据库搜索,重点关注2008年至2023年期间竞争的运营资金,并将疼痛资金作为每年获得的CIHR运营资金总额的比例制成表格。接下来,我们检查了CIHR研究所在资助年份汇总的疼痛资助比例。结果:我们确定了20,126个操作补助,其中459个是针对疼痛的。2019年,疼痛资金的最高水平为3.32%,平均水平(SD)为2.13%(0.70%)。从2008年到2023年,资金停滞不前(r2 = 0.10, P = 0.23)。肌肉骨骼健康和关节炎研究所分配给疼痛研究的资金比例最大(11.40%)。在13所研究所中,有8所对疼痛研究的投入不足其运营资金的1%。解释:总之,CIHR的疼痛研究经费与疼痛带来的社会经济负担不匹配。我们提出三个行动项目,以改善疼痛研究经费,并最终减轻加拿大的疼痛负担。
{"title":"The pain funding gap: A database analysis of pain research funding in Canada from 2008-2023.","authors":"S S Abssy, R Bosma, S Miles, H Clarke, M Moayedi","doi":"10.1080/24740527.2025.2486835","DOIUrl":"10.1080/24740527.2025.2486835","url":null,"abstract":"<p><strong>Background: </strong>One in five Canadians experiences chronic pain, at a cost of $40.3 billion in 2019. Despite this significant burden, there are few effective treatments for pain. This gap has been recognized by Health Canada, which has put forth the <i>Action Plan for Pain in Canada</i>. Advancing our understanding of pain mechanisms and clinical trials to identify novel therapeutics are essential to address this treatment gap. However, it remains unknown whether the recommendations of the <i>Action Plan</i> have increased research investments.</p><p><strong>Methods: </strong>We investigate research investments in pain by the Canadian Institutes of Health Research (CIHR) based on publicly available data. We performed a systematic database search focused on operating funds from competitions between 2008 and 2023 and tabulated pain funding as a proportion of total CIHR operational funds granted each year. Next, we examined the proportion of pain funding across CIHR institutes aggregated across funding years.</p><p><strong>Results: </strong>We identified 20,126 operational grants, of which 459 were pain focused. The highest level of pain funding was 3.32% in 2019, and the average (SD) was 2.13% (0.70%). Funding was stagnant from 2008 to 2023 (<i>R</i> <sup>2</sup> = 0.10, <i>P</i> = 0.23). The Institute of Musculoskeletal Health and Arthritis allocated the largest proportion of funding to pain research (11.40%). Eight of the 13 institutes allocated less than 1% of their operating funds to pain research.</p><p><strong>Interpretation: </strong>In sum, CIHR pain research funding does not match the socioeconomic burden posed by pain. We propose three action items to improve pain research funding and to ultimately relieve the burden of pain in Canada.</p>","PeriodicalId":53214,"journal":{"name":"Canadian Journal of Pain-Revue Canadienne de la Douleur","volume":"9 1","pages":"2486835"},"PeriodicalIF":2.1,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A retrospective review of psychosocial correlates of chronic pain in cisgender, transgender, and gender-diverse youth receiving evaluation in interdisciplinary pediatric pain clinics. 在跨学科儿科疼痛诊所接受评估的顺性别、跨性别和性别多样化青少年慢性疼痛的社会心理相关因素的回顾性回顾。
IF 2 Q3 CLINICAL NEUROLOGY Pub Date : 2025-04-15 eCollection Date: 2024-01-01 DOI: 10.1080/24740527.2025.2477466
Crystal Tracy, Mary Lynch Milder, Lindsey Vater, Ann Lagges, Kathleen Lemanek, Sharon Wrona, Elaine Gilbert, Adam T Hirsh, Megan M Miller, Kelly Donahue, Morgan Streicher, Amy E Williams

Background: Individuals who experience social marginalization, such as transgender and gender-diverse (TGD) youth, have increased risk for poor health outcomes, including chronic pain. A better understanding of the impact of chronic pain in these populations would improve treatment and aid in reducing health care disparities. Our retrospective review of clinical data examined psychosocial correlates of pain in TGD and cisgender youth with chronic pain.

Aims: The study aim was to explore differences in psychosocial variables between TGD and cisgender youth with chronic pain. In alignment with the minority stress model, we hypothesized worse pain and pain-related disability, poorer quality of life, and more internalizing symptoms in TGD patients. The secondary aim was to explore associations among psychosocial variables in TGD and cisgender youth.

Methods: Data were collected from 140 youth (48 TGD, 92 cisgender) evaluated in pediatric pain clinics. Independent samples t-tests examined group differences in pain intensity, functional disability, quality of life, pain catastrophizing, and internalizing symptoms. Bivariate correlations were conducted for each group, and differences in the strength of correlations were evaluated using Fisher r-to-z. Institutional review board (IRB) approval was obtained for all study procedures at each participating institution prior to extraction of retrospective clinical data (Indiana 240 University IRB Protocol No. 12506, The Ohio State University College of Medicine IRB Protocol No. 16-00937). Informed consent was not required or obtained due to the retrospective nature of the study.

Results: Cisgender patients reported worse pain intensity, whereas TGD patients reported lower quality of life and more internalizing symptoms. In the combined sample, pain intensity was correlated with worse functional disability, poorer quality of life, and more catastrophic thinking. No group differences in the strength of correlations were found.

Conclusions: Results suggest that for TGD youth with chronic pain, internalizing symptoms and quality of life are important targets for treatment and improvement.

背景:经历社会边缘化的个人,如跨性别和性别多样化(TGD)青年,健康状况不佳的风险增加,包括慢性疼痛。更好地了解慢性疼痛对这些人群的影响将改善治疗并有助于减少保健差距。我们对临床资料进行回顾性回顾,检查TGD和顺性别青年慢性疼痛的心理社会相关因素。目的:研究目的是探讨TGD与顺性别青年慢性疼痛患者在心理社会变量上的差异。与少数民族压力模型一致,我们假设TGD患者有更严重的疼痛和疼痛相关的残疾,更差的生活质量和更多的内化症状。第二个目的是探索TGD和顺性别青年的社会心理变量之间的联系。方法:收集140名在儿科疼痛门诊接受评估的青少年(48名TGD, 92名顺性别)的数据。独立样本t检验检验了疼痛强度、功能残疾、生活质量、疼痛灾难化和内化症状的组间差异。对每组进行双变量相关性,并使用Fisher r-to-z评估相关性强度的差异。在提取回顾性临床数据之前,每个参与机构的所有研究程序都获得了机构审查委员会(IRB)的批准(印第安纳240大学IRB协议第12506号,俄亥俄州立大学医学院IRB协议第16-00937号)。由于研究是回顾性的,因此不需要知情同意。结果:顺性别患者报告更严重的疼痛强度,而TGD患者报告更低的生活质量和更多的内化症状。在综合样本中,疼痛强度与更严重的功能残疾、更差的生活质量和更灾难性的想法相关。没有发现相关强度的组间差异。结论:结果提示,对于伴有慢性疼痛的TGD青年,内化症状和生活质量是治疗和改善的重要目标。
{"title":"A retrospective review of psychosocial correlates of chronic pain in cisgender, transgender, and gender-diverse youth receiving evaluation in interdisciplinary pediatric pain clinics.","authors":"Crystal Tracy, Mary Lynch Milder, Lindsey Vater, Ann Lagges, Kathleen Lemanek, Sharon Wrona, Elaine Gilbert, Adam T Hirsh, Megan M Miller, Kelly Donahue, Morgan Streicher, Amy E Williams","doi":"10.1080/24740527.2025.2477466","DOIUrl":"https://doi.org/10.1080/24740527.2025.2477466","url":null,"abstract":"<p><strong>Background: </strong>Individuals who experience social marginalization, such as transgender and gender-diverse (TGD) youth, have increased risk for poor health outcomes, including chronic pain. A better understanding of the impact of chronic pain in these populations would improve treatment and aid in reducing health care disparities. Our retrospective review of clinical data examined psychosocial correlates of pain in TGD and cisgender youth with chronic pain.</p><p><strong>Aims: </strong>The study aim was to explore differences in psychosocial variables between TGD and cisgender youth with chronic pain. In alignment with the minority stress model, we hypothesized worse pain and pain-related disability, poorer quality of life, and more internalizing symptoms in TGD patients. The secondary aim was to explore associations among psychosocial variables in TGD and cisgender youth.</p><p><strong>Methods: </strong>Data were collected from 140 youth (48 TGD, 92 cisgender) evaluated in pediatric pain clinics. Independent samples <i>t</i>-tests examined group differences in pain intensity, functional disability, quality of life, pain catastrophizing, and internalizing symptoms. Bivariate correlations were conducted for each group, and differences in the strength of correlations were evaluated using Fisher <i>r</i>-to-<i>z</i>. Institutional review board (IRB) approval was obtained for all study procedures at each participating institution prior to extraction of retrospective clinical data (Indiana 240 University IRB Protocol No. 12506, The Ohio State University College of Medicine IRB Protocol No. 16-00937). Informed consent was not required or obtained due to the retrospective nature of the study.</p><p><strong>Results: </strong>Cisgender patients reported worse pain intensity, whereas TGD patients reported lower quality of life and more internalizing symptoms. In the combined sample, pain intensity was correlated with worse functional disability, poorer quality of life, and more catastrophic thinking. No group differences in the strength of correlations were found.</p><p><strong>Conclusions: </strong>Results suggest that for TGD youth with chronic pain, internalizing symptoms and quality of life are important targets for treatment and improvement.</p>","PeriodicalId":53214,"journal":{"name":"Canadian Journal of Pain-Revue Canadienne de la Douleur","volume":"8 2","pages":"2477466"},"PeriodicalIF":2.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two-Eyed Seeing in action: Project extension for community health outcomes - Indigenous chronic pain & substance use. 行动中的双眼观察:社区健康成果项目扩展——土著慢性疼痛和药物使用。
IF 2 Q3 CLINICAL NEUROLOGY Pub Date : 2025-04-04 eCollection Date: 2024-01-01 DOI: 10.1080/24740527.2025.2469213
Andrew Koscielniak, Natalie Zur Nedden, Yaadwinder Shergill, Teresa Trudeau-Magiskan, Marinna Read, Alycia Benson, Lana Ray, Andrew Smith, Virginia McEwen, Paul Francis, Alex Falcigno, Tyler Drawson, Andrea Furlan, Christopher Mushquash, Patricia A Poulin

Background: Indigenous Peoples in Canada experience health disparities, including higher rates of chronic pain. Many report distrust of the health system due to factors such as racial discrimination. A lack of appreciation and respect for Indigenous knowledges further contributes to feelings of alienation. In 2022-2023, we offered the first Project Extension for Community Healthcare Outcomes (Project ECHO) Indigenous Chronic Pain and Substance Use Health (ICP&SU) to health care providers interested in improving chronic pain care with and for Indigenous Peoples in Canada. The program reflects a Two-Eyed Seeing approach weaving together Indigenous and Western approaches to chronic pain and substance use health care.

Aims: We describe the development and implementation of Project ECHO ICP&SU.

Methods: Following guidance from the project Elder, we use storytelling, centered around the metaphor of weaving, to discuss the conception and implementation of Project ECHO ICP&SU. We also describe our engagement in sharing circles and ceremonies to share stories, knowledges, and lessons learned.

Results: With strong Anishinaabe leadership, the program was implemented as intended and reached 121 health care professionals. Lessons learned included an overt recognition of the influence of different structures and institutions on programs and for a culturally safer development and evaluation frameworks for future Project ECHOs to improve care with and for Indigenous Peoples.

Conclusions: Project ECHO can be a vehicle to enact Truth and Reconciliation Calls to Action through weaving relationships and knowledges to create culturally safer institutions and practices to improve chronic pain, substance use health, and wellness, with and for Indigenous Peoples.

背景:加拿大土著人民存在健康差异,包括慢性疼痛率较高。许多人报告说,由于种族歧视等因素,他们不信任卫生系统。缺乏对土著知识的欣赏和尊重进一步助长了疏离感。在2022-2023年,我们向有兴趣改善加拿大土著人民慢性疼痛护理的卫生保健提供者提供了第一个社区卫生保健成果项目扩展(ECHO项目)土著慢性疼痛和物质使用健康(ICP&SU)。该项目反映了一种双眼观察的方法,将土著和西方的方法结合在一起,以治疗慢性疼痛和药物使用卫生保健。目的:我们描述了项目ECHO ICP&SU的开发和实施。方法:在项目长老的指导下,我们以编织的比喻为中心,采用讲故事的方式,讨论ECHO ICP&SU项目的概念和实施。我们还描述了我们参与分享圈子和仪式,分享故事、知识和经验教训。结果:在Anishinaabe强有力的领导下,该计划按计划实施,121名卫生保健专业人员参与了该计划。所吸取的经验教训包括公开承认不同结构和机构对方案的影响,并为未来的回声项目建立文化上更安全的发展和评价框架,以改善对土著人民的照顾和对土著人民的照顾。结论:ECHO项目可以成为一种媒介,通过编织关系和知识,制定《真相与和解行动呼吁》,创造文化上更安全的机构和做法,改善土著人民的慢性疼痛、物质使用健康和健康。
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Canadian Journal of Pain-Revue Canadienne de la Douleur
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