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Experiences and perceptions of medical cannabis among people living with chronic pain and community pharmacists: a qualitative study in Canada 慢性疼痛患者和社区药剂师对医用大麻的经验和看法:加拿大的一项定性研究
Q3 CLINICAL NEUROLOGY Pub Date : 2023-09-13 DOI: 10.1080/24740527.2023.2258537
Lise Dassieu, Emilie Paul-Savoie, Élise Develay, Ana Cecilia Villela Guilhon, Line Guénette, Kadija Perreault, Hélène Beaudry, Laurent Dupuis, Claudie Audet, Anaïs Lacasse
Background The use of cannabis to treat chronic pain is under debate despite high expectations from patients. Qualitative data exploring both patients’ and health professionals’ perspectives are scarce.Aims This study aimed to understand the experiences and perceptions of people living with chronic pain and community pharmacists regarding the role of cannabis in chronic pain treatment, in the Canadian context where both medical and recreational cannabis are legal.Methods We conducted 12 online focus groups (July 2020-Februrary 2021), with 26 patients and 19 community pharmacists using semi-structured discussion guides. All discussions were audio-recorded and transcribed verbatim were analyzed using a reflexive thematic approach.Results We developed three themes related to patients’ perspectives and three themes related to pharmacists’ perspectives. Patients’ perspectives: (1) Cannabis as an alternative to other pain medications; (2) A new treatment with potential health-related risks; (3) A therapy rather than a recreational drug. Pharmacists’ perspectives: (1) Challenges in monitoring drug interactions with cannabis in the context of scarce research data; (2) Informing and treating patients self-medicating with cannabis amid its growing popularity; (3) Financial costs and legal constraints for patients.Conclusions This study highlights patients’ and pharmacists’ urgent need for reliable information regarding the benefits and risks of cannabis. Training tailored to pharmacists’ needs and evidence-based information for patients should be developed to support pharmacists’ practice, improve patients’ experience and promote safe cannabis use.
尽管患者对使用大麻治疗慢性疼痛抱有很高的期望,但仍存在争议。探索患者和卫生专业人员观点的定性数据很少。本研究旨在了解慢性疼痛患者的经验和看法,以及社区药剂师对大麻在慢性疼痛治疗中的作用,在加拿大的背景下,医疗和娱乐大麻都是合法的。方法采用半结构化讨论指南,对26名患者和19名社区药师进行了12个在线焦点小组(2020年7月- 2021年2月)。所有的讨论都进行了录音和逐字记录,并使用反身性专题方法进行分析。结果我们开发了三个与患者视角相关的主题和三个与药师视角相关的主题。患者的观点:(1)大麻作为其他止痛药的替代品;(2)有潜在健康风险的新疗法;一种治疗药物,而非娱乐性药物。药剂师的观点:(1)在缺乏研究数据的背景下监测药物与大麻相互作用的挑战;(2)在大麻日益普及的情况下,告知和治疗患者使用大麻进行自我治疗;(3)患者的经济成本和法律约束。本研究强调了患者和药剂师迫切需要关于大麻的益处和风险的可靠信息。应开发适合药剂师需求的培训,并为患者提供循证信息,以支持药剂师的做法,改善患者的体验,促进安全使用大麻。
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引用次数: 0
Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation of the Musculocutaneous Nerve for Refractory Antecubital ElbowPain-Brief Technical Report and Illustrative Case Report. 超声引导下经皮外周神经刺激肌皮神经治疗顽固性肘前关节疼痛技术报告及病例说明。
IF 2.4 Q3 CLINICAL NEUROLOGY Pub Date : 2023-08-22 eCollection Date: 2023-01-01 DOI: 10.1080/24740527.2023.2249054
Quinn Tate, Guilherme Ferreira-Dos-Santos, Darrell Vydra, Nuno Ferreira-Silva, Sahil Gupta, Mark Friedrich B Hurdle

Chronic pain following distal biceps rupture (DBR) is often nonspecific in that it may arise due to the injury, subsequent surgical repair, or a combination of factors, making the painful symptoms challenging to treat. Peripheral nerve injury in the setting of DBR most commonly affects the musculocutaneous nerve or one of its terminal branches and may lead to chronic neuropathic pain involving the elbow and lateral/radial aspect of the forearm. In this brief technical report, we describe an ultrasound-guided (USG) technique for percutaneous implantation of a peripheral nerve stimulator (PNS) targeting the musculocutaneous nerve, along with an illustrative case report of successful treatment of chronic refractory pain following DBR utilizing this technique. Six months postimplantation, the patient reported a greater than 60% baseline pain intensity reduction, and no complications were noted.

二头肌远端断裂(DBR)后的慢性疼痛通常是非特异性的,因为它可能是由损伤、随后的手术修复或多种因素的组合引起的,使疼痛症状难以治疗。DBR环境中的外周神经损伤最常见地影响肌肉皮神经或其末端分支之一,并可能导致涉及肘部和前臂外侧/径向的慢性神经性疼痛。在这份简短的技术报告中,我们描述了一种超声引导(USG)技术,用于经皮植入针对肌肉皮神经的外周神经刺激器(PNS),以及一份利用该技术成功治疗DBR后慢性顽固性疼痛的说明性病例报告。植入后6个月,患者报告基线疼痛强度减轻60%以上,未发现并发症。
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引用次数: 0
Caregiver Perspectives on Pain Sensitivity and Pain Experience in Rett Syndrome. 照顾者对Rett综合征疼痛敏感性和疼痛体验的看法。
IF 2.4 Q3 CLINICAL NEUROLOGY Pub Date : 2023-07-28 eCollection Date: 2023-01-01 DOI: 10.1080/24740527.2023.2229400
B J Byiers, A M Merbler, A Raiter, C C Burkitt, F J Symons
ABSTRACT Background Although delayed or decreased responses to pain are commonly reported among caregivers of individuals with Rett syndrome (RTT), previous studies in relatively small samples have documented that caregivers are concerned about pain, particularly due to gastrointestinal and musculoskeletal conditions. Aims The purpose of the current study was to investigate in detail caregivers’ perceptions of pain sensitivity, as well as the types, severity, and effect of pain experienced by individuals with RTT in a larger sample than previous studies. Methods A total of 51 caregivers (mostly mothers) participated in the study, which involved standardized questionnaires and interviews. The individuals with RTT ranged in age from 2 to 52 years of age, and most (n = 46; 90%) met criteria for classic RTT. Results Across the sample, 84% of caregivers reported that they believed that their child was less sensitive to pain compared to her typically developing peers. Despite this perception, 63% of caregivers reported that their child had experienced at least one form of pain in the previous 7 days, and 57% reported their child experienced at least one form of chronic pain. On average, caregivers reported that their child’s pain was of moderate severity and interfered with at least one activity of daily living. Conclusions The results suggest that pain is a substantial concern among caregivers of individuals with RTT and indicate that additional research is needed to understand the apparent paradox of frequently reported pain experiences despite widespread perceptions of decreased pain sensitivity.
背景:虽然Rett综合征(RTT)患者的护理人员对疼痛的反应延迟或减弱的报道很普遍,但之前在相对小样本的研究中已经证明,护理人员对疼痛很关注,特别是由于胃肠道和肌肉骨骼疾病。目的:当前研究的目的是在比以往研究更大的样本中详细调查护理人员对疼痛敏感性的感知,以及RTT患者所经历的疼痛的类型、严重程度和影响。方法:采用标准化问卷调查和访谈法对51名照顾者(多为母亲)进行调查。RTT患者年龄在2 ~ 52岁之间,大多数(n = 46;90%)符合经典RTT标准。结果:在整个样本中,84%的看护人报告说,他们认为他们的孩子比正常发育的同龄人对疼痛不那么敏感。尽管如此,63%的护理人员报告说他们的孩子在过去7天内至少经历过一种形式的疼痛,57%的人报告他们的孩子至少经历过一种形式的慢性疼痛。平均而言,照顾者报告他们孩子的疼痛是中等严重程度,并干扰了至少一项日常生活活动。结论:研究结果表明,疼痛是RTT患者的护理人员非常关心的问题,并表明需要进一步的研究来理解尽管普遍认为疼痛敏感性降低,但经常报告疼痛经历的明显矛盾。
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引用次数: 1
Promoting inclusion, diversity, and equity in pain science. 促进疼痛科学的包容性、多样性和公平性。
IF 2 Q3 CLINICAL NEUROLOGY Pub Date : 2023-02-22 eCollection Date: 2023-01-01 DOI: 10.1080/24740527.2022.2161272
Tonya M Palermo, Karen Deborah Davis, Didier Bouhassira, Robert W Hurley, Joel D Katz, Francis J Keefe, Michael Schatman, Dennis C Turk, David Yarnitsky
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引用次数: 0
"We survived the pandemic together": The impact of the COVID-19 pandemic on Canadian families living with chronic pain. "我们一起度过了大流行":COVID-19 大流行对加拿大慢性疼痛患者家庭的影响。
IF 2 Q3 CLINICAL NEUROLOGY Pub Date : 2023-02-06 eCollection Date: 2023-01-01 DOI: 10.1080/24740527.2022.2157251
Tieghan Killackey, Sabine Soltani, Melanie Noel, Kathryn A Birnie, Manon Choinière, M Gabrielle Pagé, Lise Dassieu, Anaïs Lacasse, Chitra Lalloo, Patricia Poulin, Samina Ali, Krista Baerg, Marco Battaglia, Fiona Campbell, Vina Mohabir, Fareha Nishat, Rachel Kelly, Tatiana Lund, Ariane Isaac-Bertrand, Myles Benayon, Isabel Jordan, Jennifer Stinson

Introduction: Pediatric chronic pain is a significant problem in Canada, affecting one in five youth. This study describes the impact of the pandemic on the experiences of Canadian families living with chronic pain through interviews with youth living with chronic pain, parents, and siblings.

Methods: Employing a qualitative descriptive design, in-depth semistructured interviews were completed with Canadian youth living with pain, as well as parents and siblings. Participants were not required to be related. Interviews were analyzed using a reflexive thematic analysis approach.

Results: Forty-four interviews were completed with 14 parents, 19 youth with chronic pain, and 11 siblings from across the country. Three key themes were developed: (1) absorbing and shifting: the toll of the pandemic on the family system (e.g., loss of coping mechanisms, shifting roles to respond to the pandemic), (2) social ambiguity and abandonment (e.g., social sacrifice and abandonment by the health care system), and (3) building community resilience: familial adaptation to the pandemic (e.g., family cohesion, confidence, and self-management).

Discussion/conclusions: Youth, parents, and siblings reported that the pandemic impacted coping strategies across the family system. These results outline the challenges youth experienced managing their pain and overall health throughout the pandemic and the resilience built within families during this time. Going forward, it would be relevant to examine how racialized and structurally marginalized youth with chronic pain and their families experienced the pandemic. Future research should examine how unexpected benefits of the pandemic (e.g., increased confidence and self-management) may be sustained into the future.

导言:在加拿大,儿童慢性疼痛是一个严重问题,每五名青少年中就有一人受到影响。本研究通过对患有慢性疼痛的青少年、父母和兄弟姐妹进行访谈,描述了这一流行病对加拿大患有慢性疼痛的家庭的影响:方法:采用定性描述设计,对患有慢性疼痛的加拿大青少年、父母和兄弟姐妹进行了深入的半结构式访谈。访谈对象不要求是亲属关系。访谈采用反思性主题分析方法进行分析:对来自全国各地的 14 名父母、19 名患有慢性疼痛的青少年和 11 名兄弟姐妹进行了 44 次访谈。形成了三个关键主题:(1) 吸收和转变:大流行病对家庭系统造成的伤害(如失去应对机制、转变角色以应对大流行病),(2) 社会模糊性和遗弃(如社会牺牲和医疗系统的遗弃),以及 (3) 建设社区复原力:家庭对大流行病的适应(如家庭凝聚力、信心和自我管理):青少年、父母和兄弟姐妹报告说,大流行病影响了整个家庭系统的应对策略。这些结果概述了在整个大流行期间青少年在控制疼痛和整体健康方面所经历的挑战,以及在此期间家庭内部所建立的复原力。展望未来,研究种族化和结构边缘化的慢性疼痛青少年及其家庭是如何经历大流行病的将具有现实意义。未来的研究应探讨大流行带来的意想不到的益处(如信心的增强和自我管理能力的提高)如何在未来持续下去。
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引用次数: 0
A Scoping Review of Gaps Identified by Primary Care Providers in Caring for Patients with Chronic Noncancer Pain. 初级保健提供者在慢性非癌性疼痛患者护理中发现的差距的范围审查。
IF 2.4 Q3 CLINICAL NEUROLOGY Pub Date : 2023-01-01 DOI: 10.1080/24740527.2022.2145940
Virginia McEwen, Mihal Michelle Esterlis, R Gianni Lorello, Abhimanyu Sud, F Marina Englesakis, Anuj Bhatia

Introduction/aim: Primary care providers (PCPs), who provide the bulk of care for patients with chronic noncancer pain (CNCP), often report knowledge gaps, limited resources, and difficult patient encounters while managing chronic pain. This scoping review seeks to evaluate gaps identified by PCPs in providing care to patients with chronic pain.

Methods: The Arksey and O'Malley framework was used for this scoping review. A broad literature search was conducted for relevant articles on gaps in knowledge and skills of PCPs and in their health care environment for managing chronic pain, with multiple search term derivatives for concepts of interest. Articles from the initial search were screened for relevance, yielding 31 studies. Inductive and deductive thematic analysis was adopted.

Results: The studies included in this review reflected a variety of study designs, settings, and methods. However, consistent themes emerged with respect to gaps in knowledge and skills for assessment, diagnosis, treatment, and interprofessional roles in chronic pain, as well as broader systemic issues including attitudes toward CNCP. A general lack of confidence in tapering high dose or ineffective opioid regimes, professional isolation, challenges in managing patients with CNCP with complex needs, and limited access to pain specialists were reported by PCPs.

Discussion/conclusions: This scoping review revealed common elements across the selected studies that will be useful in guiding creation of targeted supports for PCPs to manage CNCP. This review also yielded insights for pain clinicians at tertiary centers for supporting their PCP colleagues as well as systemic reforms required to support patients with CNCP.

简介/目的:初级保健提供者(pcp)为慢性非癌性疼痛(CNCP)患者提供大量护理,在管理慢性疼痛时经常报告知识差距,资源有限和患者遇到困难。本综述旨在评估pcp在为慢性疼痛患者提供护理方面的差距。方法:采用Arksey和O'Malley框架进行范围综述。广泛的文献检索进行了相关文章的知识和技能差距的pcp和他们的卫生保健环境管理慢性疼痛,与多个搜索词衍生感兴趣的概念。对最初搜索的文章进行相关性筛选,得到31篇研究。采用归纳和演绎的主题分析方法。结果:本综述纳入的研究反映了多种研究设计、设置和方法。然而,一致的主题出现在评估、诊断、治疗和慢性疼痛跨专业角色的知识和技能方面的差距,以及更广泛的系统性问题,包括对CNCP的态度。pcp报告了对逐渐减少高剂量或无效阿片类药物治疗方案普遍缺乏信心、专业隔离、管理具有复杂需求的CNCP患者的挑战以及获得疼痛专家的机会有限。讨论/结论:该范围审查揭示了所选研究的共同要素,这些要素将有助于指导为pcp管理CNCP提供有针对性的支持。这篇综述也为三级中心的疼痛临床医生提供了见解,以支持他们的PCP同事,以及支持CNCP患者所需的系统改革。
{"title":"A Scoping Review of Gaps Identified by Primary Care Providers in Caring for Patients with Chronic Noncancer Pain.","authors":"Virginia McEwen,&nbsp;Mihal Michelle Esterlis,&nbsp;R Gianni Lorello,&nbsp;Abhimanyu Sud,&nbsp;F Marina Englesakis,&nbsp;Anuj Bhatia","doi":"10.1080/24740527.2022.2145940","DOIUrl":"https://doi.org/10.1080/24740527.2022.2145940","url":null,"abstract":"<p><strong>Introduction/aim: </strong>Primary care providers (PCPs), who provide the bulk of care for patients with chronic noncancer pain (CNCP), often report knowledge gaps, limited resources, and difficult patient encounters while managing chronic pain. This scoping review seeks to evaluate gaps identified by PCPs in providing care to patients with chronic pain.</p><p><strong>Methods: </strong>The Arksey and O'Malley framework was used for this scoping review. A broad literature search was conducted for relevant articles on gaps in knowledge and skills of PCPs and in their health care environment for managing chronic pain, with multiple search term derivatives for concepts of interest. Articles from the initial search were screened for relevance, yielding 31 studies. Inductive and deductive thematic analysis was adopted.</p><p><strong>Results: </strong>The studies included in this review reflected a variety of study designs, settings, and methods. However, consistent themes emerged with respect to gaps in knowledge and skills for assessment, diagnosis, treatment, and interprofessional roles in chronic pain, as well as broader systemic issues including attitudes toward CNCP. A general lack of confidence in tapering high dose or ineffective opioid regimes, professional isolation, challenges in managing patients with CNCP with complex needs, and limited access to pain specialists were reported by PCPs.</p><p><strong>Discussion/conclusions: </strong>This scoping review revealed common elements across the selected studies that will be useful in guiding creation of targeted supports for PCPs to manage CNCP. This review also yielded insights for pain clinicians at tertiary centers for supporting their PCP colleagues as well as systemic reforms required to support patients with CNCP.</p>","PeriodicalId":53214,"journal":{"name":"Canadian Journal of Pain-Revue Canadienne de la Douleur","volume":"7 1","pages":"2145940"},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10848879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preliminary clinical testing to inform development of the Critical Care Pain Observation Tool for Families (CPOT-Fam). 初步临床试验,为家庭重症监护疼痛观察工具(CPOT-Fam)的发展提供信息。
IF 2.4 Q3 CLINICAL NEUROLOGY Pub Date : 2023-01-01 DOI: 10.1080/24740527.2023.2235399
Anmol Shahid, Bonnie G Sept, Victoria S Owen, Corson Johnstone, Rameiya Paramalingam, Stephana J Moss, Rebecca Brundin-Mather, Karla D Krewulak, Andrea Soo, Jeanna Parsons-Leigh, Céline Gélinas, Kirsten M Fiest, Henry T Stelfox

Introduction: Many patients in the intensive care unit (ICU) cannot communicate. For these patients, family caregivers (family members/close friends) could assist in pain assessment. We previously adapted the Critical Care Pain Observation Tool (CPOT) for family caregiver use (CPOT-Fam). In this study, we conducted preliminary clinical evaluation of the CPOT-Fam to inform further tool development.

Methods: For preliminary testing, we collected (1) pain assessments of patients in the ICU from family caregivers (CPOT-Fam) and nurses (CPOT) and determined the degree of agreement (kappa coefficient, κ) and (2) collected openended feedback on the CPOT-Fam from family caregivers. For refinement, we used preliminary testing data to refine the CPOT-Fam with a multidisciplinary working group.

Results: We assessed agreement between family caregiver and nurse pain scores for 29 patients. Binary agreement (κ) between CPOT-Fam and CPOT item scores (scores ≥2 considered indicative of significant pain) was fair, κ = 0.43 (95% confidence interval [CI] 0.18-0.69). Agreement was highest for the CPOT-Fam items ventilator compliance/vocalization (weighted κ = 0.48, 95% CI 0.15-0.80) and lowest for muscle tension (weighted κ = 0.10, 95% [CI] -0.17 to 0.20). Most participants (n = 19; 69.0%) reported a very positive experience using the CPOT-Fam, describing it as "good" and "easy-to-use/clear/straightforward." We iteratively refined the CPOT-Fam over five cycles using the data collected until no further revisions were suggested.

Conclusion: Our preliminary clinical testing suggests that family involvement in pain assessment in the ICU is well perceived. The CPOT-Fam has been further refined and is now ready for clinical pilot testing to determine its feasibility and acceptability.

导读:重症监护病房(ICU)的许多患者无法沟通。对于这些患者,家庭照顾者(家庭成员/亲密朋友)可以帮助评估疼痛。我们之前改编了重症监护疼痛观察工具(CPOT)供家庭护理人员使用(CPOT- fam)。在这项研究中,我们对CPOT-Fam进行了初步的临床评估,为进一步的工具开发提供信息。方法:为了进行初步测试,我们收集(1)家庭护理人员(CPOT- fam)和护士(CPOT)对ICU患者的疼痛评估,并确定一致性程度(kappa系数,κ);(2)收集家庭护理人员对CPOT- fam的开放式反馈。为了改进,我们与多学科工作组一起使用初步测试数据来改进CPOT-Fam。结果:我们评估了29例患者的家庭照顾者和护士疼痛评分之间的一致性。CPOT- fam和CPOT项目评分(评分≥2被认为是明显疼痛的标志)之间的二元一致性(κ)是公平的,κ = 0.43(95%可信区间[CI] 0.18-0.69)。CPOT-Fam项目呼吸机依从性/发声的一致性最高(加权κ = 0.48, 95% CI 0.15-0.80),肌肉张力的一致性最低(加权κ = 0.10, 95% [CI] -0.17至0.20)。大多数参与者(n = 19;69.0%)报告了使用CPOT-Fam的非常积极的体验,将其描述为“好”和“易于使用/清晰/直接”。我们使用收集到的数据,在五个周期内迭代地改进了CPOT-Fam,直到没有进一步的修订建议。结论:我们的初步临床试验表明,家庭参与在ICU疼痛评估是公认的。CPOT-Fam已经进一步完善,现在准备进行临床试验,以确定其可行性和可接受性。
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引用次数: 1
Understanding the Experience and Impacts of Brain Fog in Chronic Pain: A Scoping Review. 理解慢性疼痛中的脑雾体验和影响:一项范围综述。
IF 2.4 Q3 CLINICAL NEUROLOGY Pub Date : 2023-01-01 DOI: 10.1080/24740527.2023.2217865
Ronessa Dass, Mohini Kalia, Jocelyn Harris, Tara Packham

Introduction: Approximately 15% to 40% of persons with chronic pain as a primary disorder experience brain fog. Prior research has investigated the etiology of "brain fog" in conditions in which pain presents as a key feature (e.g., fibromyalgia). However, it remains understudied in the context of chronic 10 musculoskeletal pain. Following current scoping review guidelines, we obtained stakeholder input from patient and health care professionals (HCPs) to define this phenomenon. Specific aims of this review were to (1) identify factors contributing to brain fog, (2) identify the functional correlates of brain fog and assessments used to measure them, and (3) establish a definition of brain fog that can be employed by researchers and HCPs to advance research and care.

Methods: A scoping review was conducted using recommendations of the Joanna Briggs Institute methodology of scoping reviews and the Levac et al methodology. Embase, Cinahl, PsycINFO, and Medline was searched to identify relevant sources. Findings were verified with patient and healthcare professionals.

Results: We identified four 15 key features of brain fog: perceived variability, subjective cognitive dysfunction, participation limitations, and changes in functional activities. We developed a model of brain fog illustrating the overlapping categories of contributors to brain fog in chronic musculoskeletal pain: (1) neuroanatomical and neurophysiological, (2) mental health/emotional, and (3) environmental/lifestyle.

Conclusion: The results of this scoping review conclude that the inconsistency in research regarding brain fog in 20 chronic musculoskeletal pain is obstructing a clear understanding of the phenomenon and therefore may be impeding persons with chronic pain and brain fog from receiving optimal care.

简介:大约15%至40%的慢性疼痛为原发性疾病的人经历脑雾。先前的研究已经调查了以疼痛为主要特征(如纤维肌痛)的情况下“脑雾”的病因。然而,它在慢性肌肉骨骼疼痛的背景下仍未得到充分研究。根据当前的范围审查指南,我们从患者和卫生保健专业人员(HCPs)那里获得了利益相关者的意见,以定义这一现象。本综述的具体目的是:(1)确定导致脑雾的因素,(2)确定脑雾的功能相关性和用于测量脑雾的评估,以及(3)建立脑雾的定义,供研究人员和HCPs使用,以推进研究和护理。方法:采用乔安娜布里格斯研究所的范围审查方法和Levac等人的方法进行范围审查。检索Embase, Cinahl, PsycINFO和Medline以确定相关来源。结果与患者和医疗保健专业人员进行了验证。结果:我们确定了脑雾的4个15个关键特征:感知变异性、主观认知功能障碍、参与限制和功能活动的变化。我们开发了一个脑雾模型,说明慢性肌肉骨骼疼痛中脑雾的重叠类别:(1)神经解剖学和神经生理学,(2)心理健康/情绪,(3)环境/生活方式。结论:本综述的结果表明,关于20例慢性肌肉骨骼疼痛的脑雾研究的不一致性阻碍了对这一现象的清晰理解,因此可能阻碍了慢性疼痛和脑雾患者获得最佳护理。
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引用次数: 0
The Efficacy of Graded Motor Imagery and Its Components on Phantom Limb Pain and Disability: A Systematic Review and Meta-Analysis. 分级运动意象及其成分对幻肢疼痛和残疾的疗效:系统回顾和meta分析。
IF 2.4 Q3 CLINICAL NEUROLOGY Pub Date : 2023-01-01 DOI: 10.1080/24740527.2023.2188899
Katleho Limakatso, Aidan G Cashin, Sam Williams, Jack Devonshire, Romy Parker, James H McAuley

Introduction: Graded Motor Imagery (GMI) is a non-invasive and inexpensive therapy used to treat Phantom Limb Pain (PLP) by sequentially activating motor networks in such a way that movement and pain are unpaired. The objective of this systematic review was to critically appraise relevant data on the efficacy of GMI and its components for reducing PLP and disability in amputees.

Methods: We searched 11 electronic databases for controlled trials investigating GMI and its components in amputees with PLP from inception until February 2023. Two reviewers independently screened studies and extracted relevant data. Study-level data were entered using the inverse variance function of the Review Manager 5 and pooled with the random effects model.

Results: Eleven studies with varying risk of bias were eligible. No eligible study considered left/right judgement tasks in isolation. Studies showed no effect for imagined movements, but positive effects were seen for GMI [weighted mean difference: -21.29 (95%CI: -31.55, -11.02), I2= 0%] and mirror therapy [weighted mean difference: -8.55 (95%CI: -14.74, -2.35, I2= 61%]. A comparison of mirror therapy versus sham showed no difference [weighted mean difference: -4.43 (95%CI: -16.03, 7.16), I2= 51%].

Conclusion: Our findings suggest that GMI and mirror therapy may be effective for reducing PLP. However, this conclusion was drawn from a limited body of evidence, and the certainty of the evidence was very low. Therefore, rigorous, high-quality trials are needed to address the gap in the literature and inform practice.

分级运动意象(GMI)是一种非侵入性和廉价的治疗方法,用于治疗幻肢痛(PLP),通过顺序激活运动网络,使运动和疼痛不配对。本系统综述的目的是批判性地评估GMI及其成分在减少截肢者PLP和残疾方面的有效性的相关数据。方法:我们检索了11个电子数据库,检索了自PLP截肢患者成立至2023年2月期间调查GMI及其组成部分的对照试验。两位审稿人独立筛选研究并提取相关数据。使用Review Manager 5的逆方差函数输入研究水平的数据,并与随机效应模型合并。结果:11项不同偏倚风险的研究入选。没有合格的研究单独考虑左/右判断任务。研究显示对想象运动没有影响,但对GMI有积极影响[加权平均差:-21.29 (95%CI: -31.55, -11.02), I2= 0%]和镜像治疗[加权平均差:-8.55 (95%CI: -14.74, -2.35, I2= 61%]。镜像治疗与假手术比较无差异[加权平均差:-4.43 (95%CI: -16.03, 7.16), I2= 51%]。结论:我们的研究结果提示GMI和镜像治疗可能有效降低PLP。然而,这一结论是从有限的证据中得出的,而且证据的确定性非常低。因此,需要严格的、高质量的试验来解决文献中的差距,并为实践提供信息。
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引用次数: 0
Chronic Pain: A Case Application of a Novel Framework to Guide Interprofessional Assessment and Intervention in Primary Care. 慢性疼痛:一个指导初级保健跨专业评估和干预的新框架的案例应用。
IF 2.4 Q3 CLINICAL NEUROLOGY Pub Date : 2023-01-01 DOI: 10.1080/24740527.2023.2228851
Jay Reaume

Background: Chronic pain is a complex condition that poses challenges in assessment and treatment. Primary care teams, especially in rural areas, may have a role in managing this population, providing interprofessional care to optimize patient outcomes. Tools are needed to aid these clinicians in assessing chronic pain.

Aims: The aim of this article is to present the case application of a clinical reasoning framework proposed by Walton and Elliott, which is used to identify drivers of chronic pain in a 61-year-old male patient with a remote history of spinal injury. Furthermore, it aims to demonstrate that an interprofessional, individualized intervention strategy can improve patient outcomes.

Methods: This case took place in a multidisciplinary primary care team in rural northern Ontario, Canada. An assessment was completed by the author, including collection of the patient's history, a medication review, and the use of multiple validated patient-reported outcome measures (PROMs), all of which were used in applying the framework.

Results: Three relevant drivers of his pain experience were identified: central nociplastic, cognitive/belief, and emotional/affective. A pharmacist and social worker then used multimodal interventions to address these drivers, which yielded improvements in scores on multiple validated pain measures but also improved the patient's self-reported quality of life.

Conclusions: A clinical reasoning framework can provide a basis for identifying drivers of chronic pain during assessment and guide primary care clinicians to targeted interventions. Broader applications of this framework by primary care providers could serve to increase capacity for managing chronic pain in Canada.

背景:慢性疼痛是一种复杂的疾病,在评估和治疗方面提出了挑战。初级保健团队,特别是在农村地区,可以在管理这一人群中发挥作用,提供跨专业护理以优化患者的预后。需要工具来帮助这些临床医生评估慢性疼痛。目的:本文的目的是介绍由Walton和Elliott提出的临床推理框架的案例应用,该框架用于识别61岁有脊柱损伤病史的男性慢性疼痛驱动因素。此外,它的目的是证明一个跨专业,个性化的干预策略可以改善患者的结果。方法:本病例发生在加拿大安大略省北部农村的一个多学科初级保健小组。作者完成了一项评估,包括收集患者的病史,进行药物审查,并使用多种经过验证的患者报告的结果测量(PROMs),所有这些都用于应用该框架。结果:确定了他的疼痛经历的三个相关驱动因素:中枢伤害性、认知/信念和情感/情感。药剂师和社会工作者随后使用多模式干预来解决这些驱动因素,这不仅提高了多种有效疼痛测量的得分,而且还改善了患者自我报告的生活质量。结论:临床推理框架可以为评估慢性疼痛的驱动因素提供基础,并指导初级保健临床医生进行有针对性的干预。初级保健提供者更广泛地应用这一框架可以提高加拿大管理慢性疼痛的能力。
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Canadian Journal of Pain-Revue Canadienne de la Douleur
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