首页 > 最新文献

Lancet Regional Health-Europe最新文献

英文 中文
Prioritising meaningful outcomes in the practice evaluation of new chlamydia testing guidelines 在新的衣原体检测指南的实践评估中优先考虑有意义的结果
IF 13 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-01 Epub Date: 2026-01-08 DOI: 10.1016/j.lanepe.2025.101579
Zoïe W. Alexiou , Nicole H.T.M. Dukers-Muijrers
{"title":"Prioritising meaningful outcomes in the practice evaluation of new chlamydia testing guidelines","authors":"Zoïe W. Alexiou , Nicole H.T.M. Dukers-Muijrers","doi":"10.1016/j.lanepe.2025.101579","DOIUrl":"10.1016/j.lanepe.2025.101579","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"61 ","pages":"Article 101579"},"PeriodicalIF":13.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145938537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new path for assisted dying in Europe: France's middle way 欧洲辅助死亡的新道路:法国的中间道路。
IF 13 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-01 Epub Date: 2026-02-05 DOI: 10.1016/j.lanepe.2026.101617
The Lancet Regional Health – Europe
{"title":"A new path for assisted dying in Europe: France's middle way","authors":"The Lancet Regional Health – Europe","doi":"10.1016/j.lanepe.2026.101617","DOIUrl":"10.1016/j.lanepe.2026.101617","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"61 ","pages":"Article 101617"},"PeriodicalIF":13.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146144483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of adults with community-acquired bacterial meningitis in the Netherlands: a prospective nationwide cohort study 荷兰成人社区获得性细菌性脑膜炎的结局:一项前瞻性全国队列研究
IF 13 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-01 Epub Date: 2025-11-14 DOI: 10.1016/j.lanepe.2025.101529
Evelien H.G.M. Drost, Eva N. Schepers, Nora Chekrouni, Thijs M. van Soest, Diederik L.H. Koelman, Merijn W. Bijlsma, Matthijs C. Brouwer, Diederik van de Beek

Background

Bacterial meningitis is associated with high rates of unfavourable outcome. We conducted a nationwide prospective study in the Netherlands to evaluate outcome in adults with bacterial meningitis, focusing on pathogen-specific differences, risk factors for unfavourable outcomes, and neurological sequelae.

Methods

Adult patients with community-acquired bacterial meningitis confirmed by lumbar puncture were identified through the database of the Netherlands Reference Laboratory for Bacterial Meningitis and prospectively included. Neurological examinations were performed on admission and discharge by the treating physician, and outcome was assessed using the Glasgow Outcome Scale, with scores of 1–4 classified as unfavourable. Logistic regression was used to evaluate the association between potential predictors and outcome.

Findings

Between January 1, 2006 and January 1, 2024, 2974 patients were included. Streptococcus pneumoniae was the most common pathogen (2029/2974; 68%), followed by Neisseria meningitidis (329/2974; 11%), Listeria monocytogenes (182/2974; 6%), Haemophilus influenzae (119/2974; 4%) and Streptococcus pyogenes (83/2974; 3%). Overall mortality was 17% (516/2974) and remained stable over 18 years (odds ratio per admission year 0·99 [95% CI 0·97–1·01]). Mortality was highest for L. monocytogenes (58/182; 32%), S. pyogenes (16/83; 19%), and S. pneumoniae (365/2029; 18%). Unfavourable outcome occurred in 1161/2974 patients (39%; 95% CI 37–41), and key predictors included advanced age, prolonged symptom duration, systemic or cerebral compromise, low CSF white-cell counts, and absence of adjunctive dexamethasone. Among survivors, neurological sequelae occurred in 1146/2088 patients (55%), including hearing impairment (692/2197; 31%) and cognitive impairment (481/2108; 23%), with highest rates following S. pneumoniae (881/1419; 62%), and S. pyogenes (44/59; 75%).

Interpretation

Mortality and morbidity from bacterial meningitis remain high, especially in L. monocytogenes, S. pyogenes, and S. pneumoniae infections. These findings highlight an urgent need for enhanced vaccination strategies, timely recognition, and improved therapies.

Funding

Netherlands Organization for Health Research and Development (ZonMW).
背景:细菌性脑膜炎与高不良结局率相关。我们在荷兰进行了一项全国范围的前瞻性研究,以评估成人细菌性脑膜炎的预后,重点关注病原体特异性差异、不利预后的危险因素和神经系统后遗症。方法通过荷兰细菌性脑膜炎参考实验室数据库筛选经腰椎穿刺确诊的成年社区获得性细菌性脑膜炎患者,并纳入前瞻性研究。入院和出院时由主治医生进行神经系统检查,并使用格拉斯哥结果量表评估结果,得分为1-4分为不利。使用逻辑回归来评估潜在预测因素与结果之间的关系。在2006年1月1日至2024年1月1日期间,纳入了2974名患者。最常见的病原体是肺炎链球菌(2029/2974;68%),其次是脑膜炎奈瑟菌(329/2974;11%)、单核细胞增生李斯特菌(182/2974;6%)、流感嗜血杆菌(119/2974;4%)和化脓性链球菌(83/2974;3%)。总死亡率为17%(516/2974),在18年内保持稳定(每入院年的优势比0.99 [95% CI 0.97 - 1.01])。死亡率最高的是单核增生乳杆菌(58/182;32%)、化脓性乳杆菌(16/83;19%)和肺炎乳杆菌(365/2029;18%)。1161/2974例患者出现了不良结果(39%;95% CI 37-41),主要预测因素包括高龄、症状持续时间延长、全身或脑损伤、脑脊液白细胞计数低和未使用地塞米松辅助治疗。在幸存者中,1146/2088例患者(55%)出现神经系统后遗症,包括听力障碍(692/2197;31%)和认知障碍(481/2108;23%),发病率最高的是肺炎链球菌(881/1419;62%)和化脓性链球菌(44/59;75%)。细菌性脑膜炎的死亡率和发病率仍然很高,尤其是单核细胞增生乳杆菌、化脓性乳杆菌和肺炎乳杆菌感染。这些发现强调了加强疫苗接种策略、及时认识和改进治疗的迫切需要。荷兰卫生研究与发展组织(卫生研究与发展组织)。
{"title":"Outcomes of adults with community-acquired bacterial meningitis in the Netherlands: a prospective nationwide cohort study","authors":"Evelien H.G.M. Drost,&nbsp;Eva N. Schepers,&nbsp;Nora Chekrouni,&nbsp;Thijs M. van Soest,&nbsp;Diederik L.H. Koelman,&nbsp;Merijn W. Bijlsma,&nbsp;Matthijs C. Brouwer,&nbsp;Diederik van de Beek","doi":"10.1016/j.lanepe.2025.101529","DOIUrl":"10.1016/j.lanepe.2025.101529","url":null,"abstract":"<div><h3>Background</h3><div>Bacterial meningitis is associated with high rates of unfavourable outcome. We conducted a nationwide prospective study in the Netherlands to evaluate outcome in adults with bacterial meningitis, focusing on pathogen-specific differences, risk factors for unfavourable outcomes, and neurological sequelae.</div></div><div><h3>Methods</h3><div>Adult patients with community-acquired bacterial meningitis confirmed by lumbar puncture were identified through the database of the Netherlands Reference Laboratory for Bacterial Meningitis and prospectively included. Neurological examinations were performed on admission and discharge by the treating physician, and outcome was assessed using the Glasgow Outcome Scale, with scores of 1–4 classified as unfavourable. Logistic regression was used to evaluate the association between potential predictors and outcome.</div></div><div><h3>Findings</h3><div>Between January 1, 2006 and January 1, 2024, 2974 patients were included. <em>Streptococcus pneumoniae</em> was the most common pathogen (2029/2974; 68%), followed by <em>Neisseria meningitidis</em> (329/2974; 11%), <em>Listeria monocytogenes</em> (182/2974; 6%), <em>Haemophilus influenzae</em> (119/2974; 4%) and <em>Streptococcus pyogenes</em> (83/2974; 3%). Overall mortality was 17% (516/2974) and remained stable over 18 years (odds ratio per admission year 0·99 [95% CI 0·97–1·01]). Mortality was highest for <em>L</em>. <em>monocytogenes</em> (58/182; 32%), <em>S</em>. <em>pyogenes</em> (16/83; 19%), and <em>S</em>. <em>pneumoniae</em> (365/2029; 18%). Unfavourable outcome occurred in 1161/2974 patients (39%; 95% CI 37–41), and key predictors included advanced age, prolonged symptom duration, systemic or cerebral compromise, low CSF white-cell counts, and absence of adjunctive dexamethasone. Among survivors, neurological sequelae occurred in 1146/2088 patients (55%), including hearing impairment (692/2197; 31%) and cognitive impairment (481/2108; 23%), with highest rates following <em>S</em>. <em>pneumoniae</em> (881/1419; 62%), and <em>S</em>. <em>pyogenes</em> (44/59; 75%).</div></div><div><h3>Interpretation</h3><div>Mortality and morbidity from bacterial meningitis remain high, especially in <em>L</em>. <em>monocytogenes</em>, <em>S</em>. <em>pyogenes</em>, and <em>S</em>. <em>pneumoniae</em> infections. These findings highlight an urgent need for enhanced vaccination strategies, timely recognition, and improved therapies.</div></div><div><h3>Funding</h3><div>Netherlands Organization for Health Research and Development (ZonMW).</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"61 ","pages":"Article 101529"},"PeriodicalIF":13.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145499912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sexually transmitted infection testing and key outcomes following implementation of online postal self-sampling into sexual health services in England: a retrospective observational study of routinely collected service-level healthcare data 在英格兰性健康服务中实施在线邮政自我抽样后的性传播感染检测和主要结果:对常规收集的服务水平卫生保健数据的回顾性观察研究
IF 13 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-01 Epub Date: 2025-11-29 DOI: 10.1016/j.lanepe.2025.101541
Jo Gibbs , Oliver Stirrup , Anna Tostevin , Alison Howarth , Claire Dewsnap , Jonathan D.C. Ross , Andy Williams , Vicky Tittle , Sara Day , Jack Brown , David Crundwell , Louise J. Jackson , Catherine H. Mercer , Jessica Sheringham , Ann Sullivan , Andrew J. Winter , Geoff Wong , Andrew Copas , Fiona Burns
<div><h3>Background</h3><div>A shift to online postal self-sampling (OPSS) for sexually transmitted infections (STIs) in high-income settings has occurred. We evaluate whether introduction of OPSS in England is associated with changes in testing activity and if this differs by population characteristics.</div></div><div><h3>Methods</h3><div>A retrospective study of sexual health (online and clinic-based) service-level data, across three case study areas (CSAs) that implemented OPSS at different times, using different models, and whose populations have different socio-demographic profiles, between 01/01/2015 and 31/12/2022 (from 01/08/2014 in CSA1 to ensure 12 months pre-OPSS). The primary outcome was chlamydia/gonorrhoea and HIV testing activity. We evaluated change over time using selected calendar years, with total activity following introduction of OPSS (2019 and 2022) compared to pre-OPSS periods (CSA1, 2014–2015, CSA2 2017, CSA3 2019), and whether outcome changes differed by socio-demographic characteristics.</div></div><div><h3>Findings</h3><div>In all CSAs chlamydia/gonorrhoea and HIV testing activity increased following introduction of OPSS with incidence rate ratios (IRR) for chlamydia/gonorrhoea testing in 2022 compared to pre-OPSS baseline ranging from 2.1 (95% CI 2.1–2.2) in CSA1 to 2.5 (95% CI 2.4–2.5) in CSA3, and for HIV testing from 1.5 (95% CI 1.5–1.5) in CSA1 to 2.8 (95% CI 2.8–2.8) in CSA2. Differences existed across all demographic characteristics in the relative change in testing incidence (all P < 0.0001 for chlamydia/gonorrhoea). Higher testing activity via OPSS was seen among men who have sex with men (MSM), particularly in CSAs1-2 for chlamydia/gonorrhoea (IRR2.9 (95% CI 2.8–3.1) and 3.6 (95% CI 3.5–3.7) in MSM compared to 1.7 (95% CI 1.7–1.8)and 1.8 (95% CI 1.8–1.8) in men who have sex exclusively with women (MSEW) for 2022 <em>vs</em> pre-OPSS). In CSA3, the largest relative increase occurred in women (IRR 3.2 (95% CI 3.1–3.3), compared to IRR 1.9 (95% CI 1.8–1.9) in MSEW). The most deprived areas had the lowest relative increase in chlamydia/gonorrhoea testing uptake (1.9–2.1 for CSA1-3).</div></div><div><h3>Interpretation</h3><div>Despite a reduction in clinic-based testing linked to COVID-19, the introduction of OPSS has been associated with increases in overall testing activity. OPSS uptake was lower among populations with greater potential for unmet need, such as individuals living in more deprived areas. Although OPSS is available to all people living within the commissioned areas, in practice not all individuals with a need for STI testing are aware of it or have the confidence and ability to access it. Differences across all socio-demographic characteristics in the relative change in testing could inadvertently increase existing inequalities in access to care and it is important to offer choice of mode of testing for service users.</div></div><div><h3>Funding</h3><div><span>National Institute for Health and C
在高收入环境中,性传播感染(STIs)已转向在线邮政自我抽样(OPSS)。我们评估了在英格兰引入OPSS是否与检测活动的变化有关,以及这种变化是否因人群特征而异。方法回顾性分析2015年1月1日至2022年12月31日(CSA1从2014年1月1日开始,以确保12个月前实施OPSS)三个案例研究区(CSA1)在不同时间、使用不同模型、人口具有不同社会人口特征的性健康(在线和基于诊所的)服务水平数据。主要结果是衣原体/淋病和艾滋病毒检测活动。我们使用选定的日历年评估随时间的变化,将引入OPSS(2019年和2022年)后的总活动与OPSS前时期(CSA1, 2014-2015年,CSA2 2017年,CSA3 2019年)进行比较,以及结果变化是否因社会人口特征而异。在所有csa中,引入OPSS后衣原体/淋病和艾滋病毒检测活动增加,与OPSS前基线相比,2022年衣原体/淋病检测的发病率比(IRR)从CSA1的2.1 (95% CI 2.1 - 2.2)到CSA3的2.5 (95% CI 2.4-2.5),艾滋病毒检测从CSA1的1.5 (95% CI 1.5 - 1.5)到CSA2的2.8 (95% CI 2.8 - 2.8)。在所有人口统计学特征中,检测发生率的相对变化都存在差异(衣原体/淋病的P均为0.0001)。通过OPSS在男男性行为者(MSM)中观察到较高的检测活性,特别是在CSAs1-2中对衣原体/淋病的检测(MSM的IRR2.9 (95% CI 2.8-3.1)和3.6 (95% CI 3.5-3.7),而2022年与OPSS前相比,专门与女性发生性行为的男性(MSEW)的IRR2.9 (95% CI 1.7 - 1.8)和1.8 (95% CI 1.8 - 1.8))。在CSA3中,女性的相对增加最大(IRR为3.2 (95% CI 3.1-3.3),而MSEW的IRR为1.9 (95% CI 1.8-1.9))。最贫困地区衣原体/淋病检测的相对增幅最低(CSA1-3为1.9-2.1)。尽管与COVID-19相关的临床检测减少了,但OPSS的引入与总体检测活动的增加有关。在未满足需求的潜力较大的人群中,例如生活在较贫困地区的个人,OPSS的吸收较低。虽然OPSS对居住在委托地区的所有人都是可用的,但实际上并不是所有需要性病检测的人都意识到这一点,或者有信心和能力获得它。在检测的相对变化中,所有社会人口特征之间的差异可能会无意中增加获得保健方面现有的不平等,因此为服务使用者提供检测模式的选择非常重要。资助国家健康和护理研究所。
{"title":"Sexually transmitted infection testing and key outcomes following implementation of online postal self-sampling into sexual health services in England: a retrospective observational study of routinely collected service-level healthcare data","authors":"Jo Gibbs ,&nbsp;Oliver Stirrup ,&nbsp;Anna Tostevin ,&nbsp;Alison Howarth ,&nbsp;Claire Dewsnap ,&nbsp;Jonathan D.C. Ross ,&nbsp;Andy Williams ,&nbsp;Vicky Tittle ,&nbsp;Sara Day ,&nbsp;Jack Brown ,&nbsp;David Crundwell ,&nbsp;Louise J. Jackson ,&nbsp;Catherine H. Mercer ,&nbsp;Jessica Sheringham ,&nbsp;Ann Sullivan ,&nbsp;Andrew J. Winter ,&nbsp;Geoff Wong ,&nbsp;Andrew Copas ,&nbsp;Fiona Burns","doi":"10.1016/j.lanepe.2025.101541","DOIUrl":"10.1016/j.lanepe.2025.101541","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;A shift to online postal self-sampling (OPSS) for sexually transmitted infections (STIs) in high-income settings has occurred. We evaluate whether introduction of OPSS in England is associated with changes in testing activity and if this differs by population characteristics.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;A retrospective study of sexual health (online and clinic-based) service-level data, across three case study areas (CSAs) that implemented OPSS at different times, using different models, and whose populations have different socio-demographic profiles, between 01/01/2015 and 31/12/2022 (from 01/08/2014 in CSA1 to ensure 12 months pre-OPSS). The primary outcome was chlamydia/gonorrhoea and HIV testing activity. We evaluated change over time using selected calendar years, with total activity following introduction of OPSS (2019 and 2022) compared to pre-OPSS periods (CSA1, 2014–2015, CSA2 2017, CSA3 2019), and whether outcome changes differed by socio-demographic characteristics.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Findings&lt;/h3&gt;&lt;div&gt;In all CSAs chlamydia/gonorrhoea and HIV testing activity increased following introduction of OPSS with incidence rate ratios (IRR) for chlamydia/gonorrhoea testing in 2022 compared to pre-OPSS baseline ranging from 2.1 (95% CI 2.1–2.2) in CSA1 to 2.5 (95% CI 2.4–2.5) in CSA3, and for HIV testing from 1.5 (95% CI 1.5–1.5) in CSA1 to 2.8 (95% CI 2.8–2.8) in CSA2. Differences existed across all demographic characteristics in the relative change in testing incidence (all P &lt; 0.0001 for chlamydia/gonorrhoea). Higher testing activity via OPSS was seen among men who have sex with men (MSM), particularly in CSAs1-2 for chlamydia/gonorrhoea (IRR2.9 (95% CI 2.8–3.1) and 3.6 (95% CI 3.5–3.7) in MSM compared to 1.7 (95% CI 1.7–1.8)and 1.8 (95% CI 1.8–1.8) in men who have sex exclusively with women (MSEW) for 2022 &lt;em&gt;vs&lt;/em&gt; pre-OPSS). In CSA3, the largest relative increase occurred in women (IRR 3.2 (95% CI 3.1–3.3), compared to IRR 1.9 (95% CI 1.8–1.9) in MSEW). The most deprived areas had the lowest relative increase in chlamydia/gonorrhoea testing uptake (1.9–2.1 for CSA1-3).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Interpretation&lt;/h3&gt;&lt;div&gt;Despite a reduction in clinic-based testing linked to COVID-19, the introduction of OPSS has been associated with increases in overall testing activity. OPSS uptake was lower among populations with greater potential for unmet need, such as individuals living in more deprived areas. Although OPSS is available to all people living within the commissioned areas, in practice not all individuals with a need for STI testing are aware of it or have the confidence and ability to access it. Differences across all socio-demographic characteristics in the relative change in testing could inadvertently increase existing inequalities in access to care and it is important to offer choice of mode of testing for service users.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Funding&lt;/h3&gt;&lt;div&gt;&lt;span&gt;National Institute for Health and C","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"61 ","pages":"Article 101541"},"PeriodicalIF":13.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conceptualising undervaccinated populations in high-income settings: why consensus and clarity matter 高收入环境中疫苗接种不足人群的概念化:为什么共识和清晰度很重要
IF 13 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-01 Epub Date: 2026-01-09 DOI: 10.1016/j.lanepe.2025.101586
Sibylle Herzig van Wees , Ben Kasstan-Dabush , Michael J. Deml , Ifrah Mohamed Ibrahim , Sandra Mounier-Jack , Michael Edelstein
{"title":"Conceptualising undervaccinated populations in high-income settings: why consensus and clarity matter","authors":"Sibylle Herzig van Wees ,&nbsp;Ben Kasstan-Dabush ,&nbsp;Michael J. Deml ,&nbsp;Ifrah Mohamed Ibrahim ,&nbsp;Sandra Mounier-Jack ,&nbsp;Michael Edelstein","doi":"10.1016/j.lanepe.2025.101586","DOIUrl":"10.1016/j.lanepe.2025.101586","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"61 ","pages":"Article 101586"},"PeriodicalIF":13.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145938536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prioritising meaningful outcomes in the practice evaluation of new chlamydia testing guidelines—Authors’ reply 在新的衣原体检测指南的实践评估中优先考虑有意义的结果——作者的答复
IF 13 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-01 Epub Date: 2026-01-09 DOI: 10.1016/j.lanepe.2025.101580
Lotte Werner , Vita W. Jongen , Sylvia M. Bruisten , Maarten F. Schim van der Loeff , Elske Hoornenborg , Henry J.C. de Vries , Janneke C.M. Heijne
{"title":"Prioritising meaningful outcomes in the practice evaluation of new chlamydia testing guidelines—Authors’ reply","authors":"Lotte Werner ,&nbsp;Vita W. Jongen ,&nbsp;Sylvia M. Bruisten ,&nbsp;Maarten F. Schim van der Loeff ,&nbsp;Elske Hoornenborg ,&nbsp;Henry J.C. de Vries ,&nbsp;Janneke C.M. Heijne","doi":"10.1016/j.lanepe.2025.101580","DOIUrl":"10.1016/j.lanepe.2025.101580","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"61 ","pages":"Article 101580"},"PeriodicalIF":13.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145938790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient-reported, psychosocial and health economic outcomes in mild to moderate Friedreich's ataxia: baseline results of the PROFA study 轻至中度弗里德赖希共济失调患者报告的心理社会和健康经济结果:PROFA研究的基线结果
IF 13 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-01 Epub Date: 2025-12-11 DOI: 10.1016/j.lanepe.2025.101552
Marcus Grobe-Einsler , Stéphanie Borel , Maresa Buchholz , Sabrina Sayah , Rania Hilab , Lucie Pierron , Audrey Iskandar , Brittany Humphries , Claire Ewenczyk , Anna Heinzmann , Mariana Atencio , Katrin Feldmann , Vivian Maas , Jennifer Faber , Sylvia Boesch , Elisabetta Indelicato , Kathrin Reetz , Jörg B. Schulz , Almut T. Bischoff , Thomas Klopstock , Bernhard Michalowsky

Background

Friedreich ataxia (FA) is the most common autosomal recessive ataxia. Little attention has been paid to FA's impact on patient-reported, psychosocial, and health-economic outcomes. This study aimed to report these outcomes across FA's disability stages 1–5.

Methods

We assessed patients in Germany, France, and Austria as part of the PROFA study, a European multicenter observational study. The protocol included a study center visit followed by a remote mobile assessment capturing ataxia severity (SARA), daily living deficits (FARS-ADL), cognitive and affective impairments (CCAS), health-related quality of life (HRQoL: PROM-Ataxia short-form, EQ-5D-5L), mental well-being (WEMWBS), communication disabilities (COMATAX), and healthcare and informal care utilization. FARS disability stages were used to demonstrate outcomes with effect size measures (Eta-Squared, Cramér's V). Multivariate regression models evaluated associations between z-standardized outcomes and disability stages.

Findings

One hundred one patients (mean [SD]: age 35.0 [11.5]; GAA-repeat size 657 [299]; 50.5% women) were included. Activities of daily living, HRQoL, communication disabilities, and informal care utilization worsened significantly across disability stages with moderate to high effect sizes. Cognitive-affective impairments and mental well-being showed significant associations with small effect sizes. Twenty-three patients (33.3%) received formal care, while 40 (58.0%) received informal care (mean 12.2 h/week). Omaveloxolone was used by 33 patients (32.7%). Annual healthcare costs excluding Omaveloxolone were €13,620 (payer) and €32,679 (societal perspective, including informal care and productivity losses).

Interpretation

The results emphasize the multidimensional patient, societal, and economic burden of FA and the need for comprehensive care addressing physical, mental, and psychosocial health.

Funding

European Joint Programme on Rare Diseases (EJP RD).
背景弗里德赖希共济失调(FA)是最常见的常染色体隐性共济失调。很少有人关注FA对患者报告、心理社会和健康经济结果的影响。本研究旨在报告FA残疾阶段1-5的这些结果。方法:作为欧洲多中心观察性研究PROFA的一部分,我们评估了德国、法国和奥地利的患者。该方案包括一次研究中心访问,随后进行远程移动评估,包括共济失调严重程度(SARA)、日常生活缺陷(FARS-ADL)、认知和情感障碍(CCAS)、健康相关生活质量(HRQoL: promo - ataxia简式,EQ-5D-5L)、精神健康(WEMWBS)、沟通障碍(COMATAX)以及医疗保健和非正式护理的利用。FARS残疾分期采用效应量测量(Eta-Squared, cram s V)来证明结果。多变量回归模型评估z标准化结果与残疾分期之间的关联。结果纳入101例患者(平均[SD]:年龄35.0 [11.5];GAA-repeat大小657[299];50.5%为女性)。日常生活活动、HRQoL、沟通障碍和非正式护理利用在残疾阶段显著恶化,具有中高效应量。认知情感障碍和心理健康在小效应量下显示出显著的关联。23例(33.3%)患者接受正规护理,40例(58.0%)患者接受非正规护理(平均12.2小时/周)。33例(32.7%)患者使用奥马维洛酮。不包括奥马韦洛龙的年度医疗保健费用为13,620欧元(付款人)和32,679欧元(社会角度,包括非正规护理和生产力损失)。研究结果强调了FA的患者、社会和经济负担的多维性,以及对身体、精神和社会心理健康进行综合护理的必要性。资助欧洲罕见病联合规划(EJP RD)。
{"title":"Patient-reported, psychosocial and health economic outcomes in mild to moderate Friedreich's ataxia: baseline results of the PROFA study","authors":"Marcus Grobe-Einsler ,&nbsp;Stéphanie Borel ,&nbsp;Maresa Buchholz ,&nbsp;Sabrina Sayah ,&nbsp;Rania Hilab ,&nbsp;Lucie Pierron ,&nbsp;Audrey Iskandar ,&nbsp;Brittany Humphries ,&nbsp;Claire Ewenczyk ,&nbsp;Anna Heinzmann ,&nbsp;Mariana Atencio ,&nbsp;Katrin Feldmann ,&nbsp;Vivian Maas ,&nbsp;Jennifer Faber ,&nbsp;Sylvia Boesch ,&nbsp;Elisabetta Indelicato ,&nbsp;Kathrin Reetz ,&nbsp;Jörg B. Schulz ,&nbsp;Almut T. Bischoff ,&nbsp;Thomas Klopstock ,&nbsp;Bernhard Michalowsky","doi":"10.1016/j.lanepe.2025.101552","DOIUrl":"10.1016/j.lanepe.2025.101552","url":null,"abstract":"<div><h3>Background</h3><div>Friedreich ataxia (FA) is the most common autosomal recessive ataxia. Little attention has been paid to FA's impact on patient-reported, psychosocial, and health-economic outcomes. This study aimed to report these outcomes across FA's disability stages 1–5.</div></div><div><h3>Methods</h3><div>We assessed patients in Germany, France, and Austria as part of the PROFA study, a European multicenter observational study. The protocol included a study center visit followed by a remote mobile assessment capturing ataxia severity (SARA), daily living deficits (FARS-ADL), cognitive and affective impairments (CCAS), health-related quality of life (HRQoL: PROM-Ataxia short-form, EQ-5D-5L), mental well-being (WEMWBS), communication disabilities (COMATAX), and healthcare and informal care utilization. FARS disability stages were used to demonstrate outcomes with effect size measures (Eta-Squared, Cramér's V). Multivariate regression models evaluated associations between z-standardized outcomes and disability stages.</div></div><div><h3>Findings</h3><div>One hundred one patients (mean [SD]: age 35.0 [11.5]; GAA-repeat size 657 [299]; 50.5% women) were included. Activities of daily living, HRQoL, communication disabilities, and informal care utilization worsened significantly across disability stages with moderate to high effect sizes. Cognitive-affective impairments and mental well-being showed significant associations with small effect sizes. Twenty-three patients (33.3%) received formal care, while 40 (58.0%) received informal care (mean 12.2 h/week). Omaveloxolone was used by 33 patients (32.7%). Annual healthcare costs excluding Omaveloxolone were €13,620 (payer) and €32,679 (societal perspective, including informal care and productivity losses).</div></div><div><h3>Interpretation</h3><div>The results emphasize the multidimensional patient, societal, and economic burden of FA and the need for comprehensive care addressing physical, mental, and psychosocial health.</div></div><div><h3>Funding</h3><div><span>European Joint Programme on Rare Diseases</span> (EJP RD).</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"61 ","pages":"Article 101552"},"PeriodicalIF":13.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145747382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in use of Attention-Deficit Hyperactivity Disorder medications among children and adults in five European countries, 2010 to 2023: a population-based observational study 2010年至2023年五个欧洲国家儿童和成人使用注意力缺陷多动障碍药物的趋势:一项基于人群的观察性研究
IF 13 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-01 Epub Date: 2026-01-21 DOI: 10.1016/j.lanepe.2025.101556
Xintong Li , Yuchen Guo , Agustina Giuliodori Picco , Anna Palomar-Cros , Antonella Delmestri , Wai Yi Man , Isabella Kaczmarczyk , James T. Brash , Katia Verhamme , Mees Mosseveld , Talita Duarte-Salles , Daniel Prieto-Alhambra , Edward Burn

Background

An increase in the use of medications for Attention-Deficit Hyperactivity Disorder (ADHD) has been reported globally. This study aims to estimate the trends of ADHD medications use among children and adults across Europe from 2010 to 2023.

Methods

We conducted a population-level observational study using electronic health records from five European countries: Belgium, Germany, the Netherlands, Spain, and the UK. We estimated the prevalence and incidence of methylphenidate, dexamphetamine, lisdexamfetamine, atomoxetine and guanfacine use among individuals aged 3 years and older. We used the proportion of patients covered to measure treatment adherence. All analyses were reported by country and stratified by age group and sex.

Findings

The prevalence of ADHD medication use increased across all five countries during the study period. Between 2010 and 2023, prevalence rose more than threefold in the UK (from 0.12% to 0.39%) and more than doubled in the Netherlands (from 0.67% to 1.56%). Adult use increased substantially in all countries, particularly among females. In the UK, prevalence among adults aged over 25 increased from 0.01% in 2010 to approximately 0.20% in 2023, representing a more than twenty-fold increase in females and fifteen-fold in males. Although ADHD medication use remained higher among males, the sex gap in treatment narrowed over time and with increasing age. After 1-year of medication initiation, 14.9%, 16.0%, 43.9%, and 30.8% of participants were covered by treatment in Germany, the Netherlands, Spain, and the UK respectively. Among initiators, the prevalence of psychiatric conditions and prior use of psycholeptic medications was higher in females and in older age groups.

Interpretation

Over 14 years, ADHD medication prevalence increased across Europe, with varying incidence trends by country, age, and sex. Understanding the utilisation of ADHD medications can provide useful information in monitoring use, as well as for anticipation and planning to minimise potential shortages.

Funding

European Medicines Agency.
背景:全球范围内报道了注意力缺陷多动障碍(ADHD)药物使用的增加。本研究旨在估计2010年至2023年欧洲儿童和成人使用ADHD药物的趋势。方法:我们使用来自比利时、德国、荷兰、西班牙和英国五个欧洲国家的电子健康记录进行了一项人口水平的观察性研究。我们估计了3岁及以上人群中哌醋甲酯、右安非他明、利得安非他明、托莫西汀和胍法辛的患病率和发生率。我们使用覆盖的患者比例来衡量治疗依从性。所有分析均按国家报告,并按年龄组和性别分层。研究发现:在研究期间,ADHD药物使用的流行率在所有五个国家都有所增加。2010年至2023年间,英国的患病率上升了三倍多(从0.12%上升到0.39%),荷兰的患病率上升了一倍多(从0.67%上升到1.56%)。所有国家的成人使用都大幅增加,特别是在女性中。在英国,25岁以上成年人的患病率从2010年的0.01%增加到2023年的约0.20%,女性增加了20多倍,男性增加了15倍。尽管ADHD药物在男性中的使用率仍然较高,但随着时间的推移和年龄的增长,治疗方面的性别差距缩小了。服药1年后,德国、荷兰、西班牙和英国分别有14.9%、16.0%、43.9%和30.8%的参与者接受了治疗。在启动者中,精神疾病的患病率和先前使用过的精神药物在女性和老年群体中较高。解释:在过去的14年里,ADHD药物在欧洲的患病率有所增加,不同国家、年龄和性别的发病率趋势不同。了解ADHD药物的使用情况可以为监测使用情况提供有用的信息,也可以为最小化潜在短缺的预期和计划提供有用的信息。资助:欧洲药品管理局。
{"title":"Trends in use of Attention-Deficit Hyperactivity Disorder medications among children and adults in five European countries, 2010 to 2023: a population-based observational study","authors":"Xintong Li ,&nbsp;Yuchen Guo ,&nbsp;Agustina Giuliodori Picco ,&nbsp;Anna Palomar-Cros ,&nbsp;Antonella Delmestri ,&nbsp;Wai Yi Man ,&nbsp;Isabella Kaczmarczyk ,&nbsp;James T. Brash ,&nbsp;Katia Verhamme ,&nbsp;Mees Mosseveld ,&nbsp;Talita Duarte-Salles ,&nbsp;Daniel Prieto-Alhambra ,&nbsp;Edward Burn","doi":"10.1016/j.lanepe.2025.101556","DOIUrl":"10.1016/j.lanepe.2025.101556","url":null,"abstract":"<div><h3>Background</h3><div>An increase in the use of medications for Attention-Deficit Hyperactivity Disorder (ADHD) has been reported globally. This study aims to estimate the trends of ADHD medications use among children and adults across Europe from 2010 to 2023.</div></div><div><h3>Methods</h3><div>We conducted a population-level observational study using electronic health records from five European countries: Belgium, Germany, the Netherlands, Spain, and the UK. We estimated the prevalence and incidence of methylphenidate, dexamphetamine, lisdexamfetamine, atomoxetine and guanfacine use among individuals aged 3 years and older. We used the proportion of patients covered to measure treatment adherence. All analyses were reported by country and stratified by age group and sex.</div></div><div><h3>Findings</h3><div>The prevalence of ADHD medication use increased across all five countries during the study period. Between 2010 and 2023, prevalence rose more than threefold in the UK (from 0.12% to 0.39%) and more than doubled in the Netherlands (from 0.67% to 1.56%). Adult use increased substantially in all countries, particularly among females. In the UK, prevalence among adults aged over 25 increased from 0.01% in 2010 to approximately 0.20% in 2023, representing a more than twenty-fold increase in females and fifteen-fold in males. Although ADHD medication use remained higher among males, the sex gap in treatment narrowed over time and with increasing age. After 1-year of medication initiation, 14.9%, 16.0%, 43.9%, and 30.8% of participants were covered by treatment in Germany, the Netherlands, Spain, and the UK respectively. Among initiators, the prevalence of psychiatric conditions and prior use of psycholeptic medications was higher in females and in older age groups.</div></div><div><h3>Interpretation</h3><div>Over 14 years, ADHD medication prevalence increased across Europe, with varying incidence trends by country, age, and sex. Understanding the utilisation of ADHD medications can provide useful information in monitoring use, as well as for anticipation and planning to minimise potential shortages.</div></div><div><h3>Funding</h3><div><span>European Medicines Agency</span>.</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"61 ","pages":"Article 101556"},"PeriodicalIF":13.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146144476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current perspectives on psychedelic treatments in Europe 欧洲迷幻药治疗的当前观点
IF 13 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-01 Epub Date: 2025-11-20 DOI: 10.1016/j.lanepe.2025.101537
Santiago Madero , Oscar Soto-Angona , Genis Ona , Jose Sanchez-Moreno , Eduard Vieta
In this viewpoint, we explore the evolving landscape of psychedelic-assisted therapy in Europe, focusing on clinical, regulatory, and therapeutic developments. While access remains limited, recent initiatives in Switzerland, Germany, and the Czech Republic illustrate growing momentum toward regulated use. We examine the debate surrounding psychedelics as pharmacological agents versus psychotherapeutic catalysts and argue for an integrative framework that considers neurobiological mechanisms, subjective experience, and contextual factors. We focus on how their effects, particularly those involving neuroplasticity and critical periods, may interact with psychotherapeutic processes. We highlight the importance of context and psychological support in shaping outcomes and discuss the challenges of implementing scalable care models. Regulatory fragmentation and methodological complexities continue to hinder progress, but publicly funded trials such as EPIsoDE and PsyPal offer promising examples of ethical and effective approaches. In our view, the future of psychedelic therapy lies not in simplifying its complexity, but in embracing it.
在这种观点下,我们探讨了迷幻剂辅助治疗在欧洲的发展前景,重点是临床、监管和治疗的发展。虽然获取途径仍然有限,但瑞士、德国和捷克共和国最近的举措表明,监管使用的势头正在增强。我们研究了围绕致幻剂作为药物制剂与心理治疗催化剂的争论,并提出了一个考虑神经生物学机制、主观经验和环境因素的综合框架。我们关注它们的影响,特别是那些涉及神经可塑性和关键时期的影响,可能与心理治疗过程相互作用。我们强调了环境和心理支持在形成结果中的重要性,并讨论了实施可扩展护理模式的挑战。监管的分散和方法的复杂性继续阻碍着进展,但公共资助的试验,如EPIsoDE和PsyPal,提供了有希望的道德和有效方法的例子。在我们看来,迷幻疗法的未来不在于简化它的复杂性,而在于拥抱它。
{"title":"Current perspectives on psychedelic treatments in Europe","authors":"Santiago Madero ,&nbsp;Oscar Soto-Angona ,&nbsp;Genis Ona ,&nbsp;Jose Sanchez-Moreno ,&nbsp;Eduard Vieta","doi":"10.1016/j.lanepe.2025.101537","DOIUrl":"10.1016/j.lanepe.2025.101537","url":null,"abstract":"<div><div>In this viewpoint, we explore the evolving landscape of psychedelic-assisted therapy in Europe, focusing on clinical, regulatory, and therapeutic developments. While access remains limited, recent initiatives in Switzerland, Germany, and the Czech Republic illustrate growing momentum toward regulated use. We examine the debate surrounding psychedelics as pharmacological agents versus psychotherapeutic catalysts and argue for an integrative framework that considers neurobiological mechanisms, subjective experience, and contextual factors. We focus on how their effects, particularly those involving neuroplasticity and critical periods, may interact with psychotherapeutic processes. We highlight the importance of context and psychological support in shaping outcomes and discuss the challenges of implementing scalable care models. Regulatory fragmentation and methodological complexities continue to hinder progress, but publicly funded trials such as EPIsoDE and PsyPal offer promising examples of ethical and effective approaches. In our view, the future of psychedelic therapy lies not in simplifying its complexity, but in embracing it.</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"61 ","pages":"Article 101537"},"PeriodicalIF":13.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145580505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strengthening non-communicable diseases monitoring systems in Europe through a multistakeholder collaborative approach: a key priority for advancing data-driven policymaking 通过多利益攸关方合作方式加强欧洲非传染性疾病监测系统:推进数据驱动决策的关键优先事项
IF 13 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-01 Epub Date: 2025-12-11 DOI: 10.1016/j.lanepe.2025.101553
Benedetta Armocida , Hanna Tolonen , Ivo Rakovac , Beatrice Formenti , Jill Farrington , Allison Ekberg , Hector Bueno , Giovanni Capelli , Silvia Francisci , Morten S. Frydensberg , Ane Fullaondo , Linda Granlund , Yhasmine Hamu Azcarate , Torben F. Hansen , Emil Høstrup , Tomi Mäki-Opas , Luigi Palmieri , Markku Peltonen , Valentina Possenti , Marco Silano , Gauden Galea
Non-communicable diseases (NCDs) are major drivers of disability, health expenditure, and productivity loss in Europe. Effective surveillance is essential to understand evolving needs, design and evaluate interventions, and ensure accountability. This paper provides a high-level overview of NCD monitoring in Europe, focusing on cardiovascular diseases, cancer, diabetes, chronic respiratory diseases, and major modifiable risk factors. It draws on three complementary sources: the EU Joint Action on Cardiovascular Diseases and Diabetes (JACARDI, 32 countries), the Joint Action on the Prevention of NCDs (JA PreventNCD, 16 countries), and the WHO NCD Country Capacity Survey (2023, 53 WHO European Region Member States). These sources provide a comprehensive assessment of surveillance capacity, infrastructure and gaps, showing that NCD monitoring remains fragmented, underfunded, and limited in equity-sensitive data and policy integration. Strengthening governance, investment, and cross-country collaboration is crucial to build interoperable, and equity-oriented systems supporting evidence-informed decisions, accountability, and the right to health.
在欧洲,非传染性疾病是造成残疾、卫生支出和生产力损失的主要原因。有效的监测对于了解不断变化的需求、设计和评估干预措施以及确保问责制至关重要。本文提供了欧洲非传染性疾病监测的高级概述,重点关注心血管疾病、癌症、糖尿病、慢性呼吸系统疾病和主要可改变的危险因素。它利用了三个互补的来源:欧盟心血管疾病和糖尿病联合行动(JACARDI, 32个国家)、预防非传染性疾病联合行动(JA PreventNCD, 16个国家)和世卫组织非传染性疾病国家能力调查(2023年,53个世卫组织欧洲区域会员国)。这些来源提供了对监测能力、基础设施和差距的全面评估,表明非传染性疾病监测仍然分散、资金不足,并且在公平敏感数据和政策整合方面受到限制。加强治理、投资和跨国合作对于建立可互操作和面向公平的系统至关重要,该系统支持循证决策、问责制和健康权。
{"title":"Strengthening non-communicable diseases monitoring systems in Europe through a multistakeholder collaborative approach: a key priority for advancing data-driven policymaking","authors":"Benedetta Armocida ,&nbsp;Hanna Tolonen ,&nbsp;Ivo Rakovac ,&nbsp;Beatrice Formenti ,&nbsp;Jill Farrington ,&nbsp;Allison Ekberg ,&nbsp;Hector Bueno ,&nbsp;Giovanni Capelli ,&nbsp;Silvia Francisci ,&nbsp;Morten S. Frydensberg ,&nbsp;Ane Fullaondo ,&nbsp;Linda Granlund ,&nbsp;Yhasmine Hamu Azcarate ,&nbsp;Torben F. Hansen ,&nbsp;Emil Høstrup ,&nbsp;Tomi Mäki-Opas ,&nbsp;Luigi Palmieri ,&nbsp;Markku Peltonen ,&nbsp;Valentina Possenti ,&nbsp;Marco Silano ,&nbsp;Gauden Galea","doi":"10.1016/j.lanepe.2025.101553","DOIUrl":"10.1016/j.lanepe.2025.101553","url":null,"abstract":"<div><div>Non-communicable diseases (NCDs) are major drivers of disability, health expenditure, and productivity loss in Europe. Effective surveillance is essential to understand evolving needs, design and evaluate interventions, and ensure accountability. This paper provides a high-level overview of NCD monitoring in Europe, focusing on cardiovascular diseases, cancer, diabetes, chronic respiratory diseases, and major modifiable risk factors. It draws on three complementary sources: the EU Joint Action on Cardiovascular Diseases and Diabetes (JACARDI, 32 countries), the Joint Action on the Prevention of NCDs (JA PreventNCD, 16 countries), and the WHO NCD Country Capacity Survey (2023, 53 WHO European Region Member States). These sources provide a comprehensive assessment of surveillance capacity, infrastructure and gaps, showing that NCD monitoring remains fragmented, underfunded, and limited in equity-sensitive data and policy integration. Strengthening governance, investment, and cross-country collaboration is crucial to build interoperable, and equity-oriented systems supporting evidence-informed decisions, accountability, and the right to health.</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"61 ","pages":"Article 101553"},"PeriodicalIF":13.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145747383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Lancet Regional Health-Europe
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1