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Bilateral facial nerve palsy secondary to an atypical presentation of Gullain-Barré syndrome 双侧面神经麻痹继发于非典型的gullain - barr<s:1>综合征
Q4 Medicine Pub Date : 2020-11-23 DOI: 10.31436/IMJM.V8I1.769
A. Shah, Shahrin Tarmizi Che Abdullah, A. Omar, N. Ahmad, M. Rathor
Bilateral simultaneous facial nerve palsy is an extremely rare clinical entity and may occur in association with a variety of neurological, infectious, neoplastic or degenerative disorders. We describe a patient, who presented with facial diplegia and normal reflexes on examination. During the entire hospitalization, he developed no motor weakness and remained ambulatory. Whether treatment is warranted for this and other milder variants of Gullain-Barre syndrome is also discussed. Atypical presentations with preserved or brisk reflexes, can be a diagnostic dilemma.
双侧同时性面神经麻痹是一种极为罕见的临床疾病,可能与各种神经、感染、肿瘤或退行性疾病有关。我们描述了一名患者,他在检查中表现为面部双瘫和正常反射。在整个住院期间,他没有出现任何运动无力的症状,并且一直在活动。还讨论了是否有必要对这种和其他较温和的格林-巴利综合征变体进行治疗。不典型的表现与保留或快速的反射,可能是一个诊断困境。
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引用次数: 2
Syringomyelia in Pregnancy- Is Caesarean Section The Best Option For Delivery? - A Case Report 妊娠期脊髓空洞——剖腹产是分娩的最佳选择吗?-个案报告
Q4 Medicine Pub Date : 2020-11-23 DOI: 10.31436/IMJM.V8I1.768
H. G. Bilal, Roszaman Ramli, N. Wahab, Che Anuar Che Yaakob, J. Abdullah
Syringomyelia is a rare neurological disease, which is characterized by the formation of a cyst in the spinal cord. The aetiology of the disease still remains controversial. The damage to the spinal cord results in headache, weakness, stiffness and numbness on both lower and upper limbs. Only few a cases of syringomyelia in pregnancy have been reported thus far. As such, there is no standard management of intrapartum care. We present a case of symptomatic syringomyelia in pregnancy, its management and literature review. The mode of delivery with risks for vaginal route is discussed.
脊髓空洞症是一种罕见的神经系统疾病,其特征是在脊髓中形成囊肿。这种疾病的病因仍然存在争议。脊髓损伤会导致头痛、虚弱、僵硬和上肢麻木。到目前为止,只有少数几例妊娠期脊髓空洞症的报道。因此,对产时护理没有标准的管理。我们提出一例妊娠期症状性脊髓空洞症,其处理和文献复习。讨论了阴道分娩方式的风险。
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引用次数: 0
The Incidence of Thyroid Gland Invasion in Patients with Carcinoma of the Larynx who Underwent Total Laryngectomy 喉癌行全喉切除术患者甲状腺侵犯的发生率
Q4 Medicine Pub Date : 2020-11-20 DOI: 10.31436/IMJM.V18I1.232
A. Mawaddah, S. See-Sze, Marina Mb, Pua Kc, M. Abdullah-Sani
Total laryngectomy has stood the test of time as an oncologically safe surgery in the treatment of advanced carcinoma of the larynx since it was introduced by Billroth in the year 1880 The surgical management of the lymphatic and non lymphbearing structures, however, is a matter of debate. Our centre practices routine selective neck dissections (Level 11a, 111 and 1V) and at least hemithyroidectomy alongside total laryngectomy for patients with advanced carcinoma of the larynx.
自1880年Billroth提出全喉切除术以来,全喉切除术作为一种治疗晚期喉癌的肿瘤学安全手术,已经经受住了时间的考验。然而,淋巴结和非淋巴结结构的手术管理是一个有争议的问题。我们的中心为晚期喉癌患者进行常规选择性颈部解剖(11a、111和1V级),至少进行半甲状腺切除术和全喉切除术。
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引用次数: 2
Solitary Skull Metastasis as Initial Manifestation of Hepatocellular Carcinoma - A Case Report 单发颅骨转移是肝细胞癌的初始表现- 1例报告
Q4 Medicine Pub Date : 2020-11-20 DOI: 10.31436/IMJM.V8I2.758
El-Mehallawy Mn, A. MohdShafie
Metastatic spread of tumors to the skull is quite unusual and often represents diagnostic and therapeutic issues. Skull involvement can be observed in various neoplasms of epithelial origin and are most often due to lung, breast, thyroid, kidney and prostate cancers. However, skull metastases from hepatocellular carcinoma (HCC) have been rarely reported. The prognosis for patients with hepatocellular carcinoma is so poor that treatment of such distant metastatic lesion cannot be achieved before death occurs due to the primary malignancy. Therefore, the clinical manifestations of cranial metastasis prior to that of primary hepatocellular carcinoma have rarely been reported. This case illustrates a rare case of skull metastasis as an initial manifestation of hepatocellular carcinoma. Although a solitary skull metastasis prior to the diagnosis of HCC demonstrates rare metastatic behavior for HCC, especially in Asia, skull metastases from HCC should be included in the differential diagnosis of skull tumors, even if the patient is asymptomatic of liver cirrhosis.
肿瘤转移扩散到颅骨是相当罕见的,往往代表诊断和治疗问题。颅骨受累可以在各种上皮性肿瘤中观察到,最常见的是由于肺癌、乳腺癌、甲状腺癌、肾癌和前列腺癌。然而,来自肝细胞癌(HCC)的颅骨转移很少有报道。肝细胞癌患者的预后很差,由于原发恶性肿瘤,这种远处转移灶不能在死亡前得到治疗。因此,颅转移的临床表现早于原发性肝细胞癌的报道很少。本病例是一个罕见的以头颅转移为原发性肝癌的病例。尽管HCC诊断前的单发颅骨转移显示HCC的罕见转移行为,特别是在亚洲,但HCC的颅骨转移应纳入颅骨肿瘤的鉴别诊断,即使患者无肝硬化症状。
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引用次数: 0
Biomedicine and Islamic Jurisprudence in Malaysia - Quo Vadis ? 马来西亚的生物医学和伊斯兰法学——现状?
Q4 Medicine Pub Date : 2020-11-20 DOI: 10.31436/IMJM.V8I2.749
A. Shah
Islam is a way of life that rhymes with human nature.1 In harmony with its strengths, acknowledging its weaknesses and offering guidance to those who submit.2,3 Despite many misconceptions on compulsion ascribed to Islam, its practice is purely by choice.4,5 Belief in Islam is a conviction to a resolute and eternal truth, which is the unity of God. Living it, is harmonising the daily physical needs to that of constant spiritual enlightenment, neither in mutual exclusion but rather, complementary and symbiotic.
伊斯兰教是一种符合人性的生活方式与它的优点和谐相处,承认它的缺点,并为那些顺从的人提供指导。尽管伊斯兰教对强迫有许多误解,但它的做法纯粹是出于选择。4,5对伊斯兰教的信仰是对一个坚定和永恒的真理的信念,这是神的统一。生活,就是使日常的身体需要与持续的精神启蒙相协调,不是相互排斥,而是互补和共生。
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引用次数: 0
Stress and Coping Strategies among Management and Science University Students: A Qualitative Study 理工科大学生压力与应对策略的质性研究
Q4 Medicine Pub Date : 2020-11-20 DOI: 10.31436/IMJM.V8I2.751
Redhwan Aan, Sami Ar, Karim Aj, C. R, Zaleha Mi
Introduction: This study aimed to explore the associated factors related to causes of stress and coping strategies among university students. Materials and Methods: As a focus group discussion, it was universal sampling, conducted among 39 of Medical Science and Biomedicine students on their second semester from Management and Science University (MSU), Shah Alam, Malaysia. Three issues were discussed: firstly, how they define the stress; secondly, what the most important causes of stress in their life are; and thirdly, how they cope with stress. Verbal consent was obtained from all participants. Due to the small sample size, the data was analyzed manually. Results: Total of participants were 39 students, their age ranged from 21 to 26 years. Seventeen (43.6%) of the students were 21 years old and the majority were female 31 (79.5%). The most important causes of stress reported by the students were financial, lack of sleep, and family problems. In terms of coping with stress, the students were able to describe a variety of strategies to cope with their stressful situations. These included counseling services, doing meditation, sharing of problems, getting adequate sleep, and going out with friends. Conclusion: Most of the students defined stress as “a mental condition”. Lack of sleep, financial, and family problems were the most causes of stress among students. The students were able to identify some strategies to cope with stress.
前言:本研究旨在探讨大学生压力产生的相关因素及应对策略。材料和方法:作为焦点小组讨论,这是普遍抽样,在马来西亚沙阿南管理与科学大学(MSU)第二学期的39名医学和生物医学学生中进行。讨论了三个问题:第一,他们如何定义应力;其次,他们生活中最重要的压力原因是什么;第三,他们如何应对压力。得到了所有参与者的口头同意。由于样本量小,数据是手工分析的。结果:共39名学生,年龄21 ~ 26岁。年龄在21岁的学生中有17人(43.6%),其中以31岁的女性居多(79.5%)。学生们报告的压力最重要的原因是经济、睡眠不足和家庭问题。在应对压力方面,学生们能够描述各种应对压力情况的策略。这些包括咨询服务、冥想、分享问题、充足的睡眠以及与朋友外出。结论:大多数学生将压力定义为“一种精神状态”。睡眠不足、经济和家庭问题是学生压力的主要原因。学生们能够找到一些应对压力的策略。
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引用次数: 33
Osteoporosis-related life habits and knowledge about osteoporosis among women in Tabriz, Iran 伊朗大不里士妇女骨质疏松相关的生活习惯和骨质疏松知识
Q4 Medicine Pub Date : 2020-11-20 DOI: 10.31436/IMJM.V8I2.752
M. Rafraf, Behnaz Bazyun, F. Afsharnia
ABSTRACT Introduction: The objectives of this study were to investigate the calcium intake, physical activity level and knowledge about osteoporosis in women who attended health centers in Tabriz, Iran. Materials and Methods: Three hundred ninety-nine women of childbearing age were studied. Information was collected through face to face interviews with subjects. Results: The mean daily calcium intake was 689.08±393.15 mg. Majority of subjects had low or moderate physical activity levels. Only 8% of women reported high physical activity level. Knowledge about osteoporosis in majority of subjects (63.2%) was at moderate level. Educational status of subjects was positively correlated with calcium intake. There were no significant statistics relationship between calcium intake and physical activity with other studied variables. Conclusion: Public health programs are suggested to improve calcium intake of women and elevating healthy life styles. Establishment of educational workshops to health care providers and encourage and obligate them to proper consultation with women is suggested as a suitable approach for prevention of osteoporosis. KEYWORDS: Osteoporosis, Calcium intake, Physical activity, Knowledge, women
摘要简介:本研究的目的是调查在伊朗大不里士健康中心就诊的女性的钙摄入量、体育活动水平和对骨质疏松症的了解。材料与方法:对399名育龄妇女进行研究。通过与受试者面对面访谈收集信息。结果:平均每日钙摄入量为689.08±393.15mg。大多数受试者的体力活动水平较低或中等。只有8%的妇女报告说身体活动水平很高。大多数受试者(63.2%)对骨质疏松症的了解处于中等水平。受试者的教育程度与钙摄入量呈正相关。钙摄入量和体力活动与其他研究变量之间没有显著的统计学关系。结论:建议开展公共卫生活动,提高妇女钙摄入量,改善健康生活方式。建议为卫生保健提供者举办教育讲习班,鼓励并责成他们与妇女进行适当协商,以此作为预防骨质疏松症的适当方法。关键词:骨质疏松症,钙摄入量,体育活动,知识,女性
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引用次数: 9
Evaluation of anti-hypertensive drug utilisation and cost in Hospital Tengku Ampuan Afzan, Kuantan. 关丹东姑阿普曼医院抗高血压药物使用及费用评价。
Q4 Medicine Pub Date : 2020-11-20 DOI: 10.31436/IMJM.V8I2.754
Azarisman Sms, A. A., Sahimi M, Ngow Ha, Marzuki Ao, Jamalludin Ar, Sapari S, Maskon O
ABSTRACT Introduction: Hypertension is one of the most important risk factors for cardiovascular disease in Malaysia. The prevalence of hypertension nearly doubled over a ten-year period (1986 – 1996). This has resulted in a significant rise in its attendant cost. We aim to review the institutional anti-hypertensive use, the cost incurred and the implications on management in our local setting. Materials and Methods: A retrospective review of the annual cost (2006) of anti-hypertensive medications was undertaken at the Department of Pharmacy, Hospital Tengku Ampuan Afzan, a 600-bed major regional hospital on the east-coast of Malaysia. The total number of prescriptions given out and the total cost per drug is then factored to give the annual cost per drug per person in a percentage of the total annual expenditure.Results: The majority of patients were on either 2 (46.5%) or 3 (25.9%) anti-hypertensives. The most frequently prescribed medications were ACE Inhibitors (33.45%), Calcium channel blockers (29.63%), diuretics (16.67%) and s-blockers (13.64%). In terms of cost however, the Calcium channel blockers constituted the greatest percentage of the annual anti-hypertensive budget (63.67%) compared to ACE Inhibitors at just 20.04% of the annual expenditure. The least costly group of drugs is the diuretic making up 16.67% of the total annual prescriptions but only constituting 1.23% of the annual cost. Conclusion: The majority of patients were on ACE Inhibitors and/or Calcium channel blockers. This has huge monetary implications as they represent a large proportion of the annual antihypertensive allocation. There may be a need to reverse the trend in the developing world due to cost restrictions. KEYWORDS: Hypertension, Medication, Cost.
摘要简介:在马来西亚,高血压是心血管疾病最重要的危险因素之一。高血压的患病率在十年期间(1986年至1996年)几乎翻了一番。这导致了随之而来的成本大幅上升。我们的目的是审查机构抗高血压药物的使用、产生的成本以及对我们当地环境管理的影响。材料和方法:在马来西亚东海岸一家拥有600张床位的大型地区医院Tengku Ampuan Afzan医院的药学部,对2006年抗高血压药物的年度成本进行了回顾性审查。然后,将开出的处方总数和每种药物的总成本计算在内,得出每人每种药物每年的成本占年度总支出的百分比。结果:大多数患者服用2种(46.5%)或3种(25.9%)抗高血压药物。最常见的处方药是ACE抑制剂(33.45%)、钙通道阻滞剂(29.63%)、利尿剂(16.67%)和s型阻滞剂(13.64%)。然而,就成本而言,钙通道阻滞剂在年度抗高血压预算中所占比例最大(63.67%),而ACE抑制剂仅占年度支出的20.04%。成本最低的药物是利尿剂,占年度处方总额的16.67%,但仅占年度成本的1.23%。结论:大多数患者服用ACE抑制剂和/或钙通道阻滞剂。这具有巨大的货币影响,因为它们在年度抗高血压拨款中占很大比例。由于成本限制,发展中国家可能需要扭转这一趋势。关键词:高血压,药物,成本。
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引用次数: 3
Discrepancies in the diagnosis of methicillin resistant Staphylococcus aureus among different hospitals in Lahore, Pakistan 巴基斯坦拉合尔不同医院对耐甲氧西林金黄色葡萄球菌诊断的差异
Q4 Medicine Pub Date : 2020-11-20 DOI: 10.31436/IMJM.V8I2.750
T. Romeeza, A. Nadeem, J. Nauman, A. Afia, R. Kunwal
ABSTRACT Introduction: Staphylococcus aureus is a pathogen causing a wide range of infections. It changes its genome under the selection pressure of antibiotics. Methicillin resistance is commonly determined by Kirby-Bauer disc diffusion method which has low sensitivity and specificity. Thus, anti PBP-2a latex agglutination test was used to confirm the identity of those labeled as MRSA. Materials and Methods: One hundred bacterial samples characterized as MRSA according to Kirby-Bauer diffusion method were collected from different hospitals in Lahore. Results: Biochemical characterization of these MRSA isolates revealed that only 64 (64%) were actually S. aureus while the other 36 isolates (36%) were coagulase negative staphylococci. Further serological characterization revealed that among the 64 isolates of S. aureus, 50 (78%) were MRSA while 14 (22%) were MSSA. Conclusion: Therefore, overall, 50% of the bacterial strains were misidentified as MRSA. Misdiagnosis of antibiotic resistance may lead to an inappropriate prescription of medicines to these patients. KEY WORDS: MRSA, MSSA, Staphylococcus epidermidis, Agglutination
摘要简介:金黄色葡萄球菌是一种引起广泛感染的病原体。在抗生素的选择压力下,它改变了自己的基因组。甲氧西林耐药常用Kirby-Bauer盘片扩散法测定,敏感性和特异性较低。因此,采用抗PBP-2a胶乳凝集试验来确认这些标记为MRSA的人的身份。材料与方法:在拉合尔不同医院采集100份经Kirby-Bauer扩散法鉴定为MRSA的细菌样本。结果:经生化鉴定,64株(64%)为金黄色葡萄球菌,其余36株(36%)为凝固酶阴性葡萄球菌。进一步的血清学鉴定显示,64株金黄色葡萄球菌中,50株(78%)为MRSA, 14株(22%)为MSSA。结论:因此,总体而言,50%的菌株被误诊为MRSA。对抗生素耐药性的误诊可能导致对这些患者不适当的药物处方。关键词:MRSA, MSSA,表皮葡萄球菌,凝集
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引用次数: 1
Spontaneous Thrombosis of Dural Arteriovenous Malformation: A Case Report 硬脑膜动静脉畸形自发性血栓形成1例
Q4 Medicine Pub Date : 2020-11-20 DOI: 10.31436/IMJM.V8I2.756
Wz Mezlina
ABSTRACT Dural arteriovenous malformation (DAVM) is relatively rare and defined as abnormal connections or shunts between the arterial and the venous side of vascular tree located within the dura mater. Spontaneous closures of DAVM are rare and have been scarcely reported. This case report will describe the neuroimaging findings and classification of DAVM. A 50 year old lady presented with headache. Neuroimaging showed prominent serpinginous flow-void structures, cerebral angiogram confirmed the presence of DAVM at the occipital region. She had defaulted treatment and followup for 3 years. On second admission, she had a cerebral angiogram which showed normal findings with no evidence of fistulas or malformation. She was discharged well. Causes of spontaneous closure of DAVM are discussed. KEYWORDS: Dural arteriovenous malformation, Dural arteriovenous fistulae, Spontaneous closure
摘要硬脑膜动静脉畸形(DAVM)相对罕见,其定义为位于硬脑膜内的血管树的动脉和静脉侧之间的异常连接或分流。DAVM的自发闭合是罕见的,也几乎没有报道。本病例报告将描述DAVM的神经影像学表现和分类。一位50岁的女士头痛。神经影像学显示有明显的浆液性流动空隙结构,脑血管造影证实枕部存在DAVM。她缺席了3年的治疗和随访。第二次入院时,她做了脑部血管造影,结果正常,没有瘘管或畸形的证据。她出院了。讨论了DAVM自发闭合的原因。关键词:硬脑膜动静脉畸形,硬脑膜动静脉瘘,自发性闭合
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引用次数: 0
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International Medical Journal Malaysia
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