ABSRACT Introduction: Hereditary sensory neuropathy type 1 (HSN1) is the most common hereditary disorder of peripheral sensory neurons. Materials and methods: This study was carried out on 15 patients with hereditary sensory neuropathy type-1 and 10 healthy individuals as a control group. Detailed family history and thorough clinical and neurological examination were performed to all patients. Nerve conduction velocity of ulnar and lateral popliteal nerves (motor and sensory) as well as audiograms was carried out for all members of the studied groups. The laboratory study included the determination of serum C-reactive protein (CRP) and serum nucleasomes as well as molecular detection of the serine palmitoytransferase (SPTLC-1) gene mutations for all studied groups. Results: There was predominance in male who developed more sever clinical manifestations than females. The disease onset was in the second and third decades of life. Patients with HSN 1 manifested reduced conduction velocity in both motor and sensory fibers of the lateral popliteal nerve (p< 0.01) however the ulnar nerve was spared (p = 0.61). Audiometry revealed bilateral partial nerve deafness in 3 cases and complete deafness in one case. Serum CRP and nucleosomes were significantly elevated in all patients as compared to the control group (p < 0.01). The genetic study revealed mutations of the SPTLC1 in all studied patients compared to the control group. Point mutation C133W was observed in younger patients having severe clinical manifestations with prominent leg ulceration, while the point mutation C133Y was observed in the older patients complaining of hearing loss. The mutation V144D was found in patients with mild clinical presentation having minimal ulceration and no hearing abnormalities. Conclusion: The SPTLC1 gene mutations play an important role in the pathogenesis and variability in clinical presentation of HSN1 disease.
{"title":"Clinical And Genetic Study of The Sptlc1 Gene Mutation in Patients With Heridetary Sensory Neuropahty Type 1","authors":"Mourad H, F. W., El Batch M","doi":"10.31436/IMJM.V8I1.767","DOIUrl":"https://doi.org/10.31436/IMJM.V8I1.767","url":null,"abstract":"ABSRACT Introduction: Hereditary sensory neuropathy type 1 (HSN1) is the most common hereditary disorder of peripheral sensory neurons. Materials and methods: This study was carried out on 15 patients with hereditary sensory neuropathy type-1 and 10 healthy individuals as a control group. Detailed family history and thorough clinical and neurological examination were performed to all patients. Nerve conduction velocity of ulnar and lateral popliteal nerves (motor and sensory) as well as audiograms was carried out for all members of the studied groups. The laboratory study included the determination of serum C-reactive protein (CRP) and serum nucleasomes as well as molecular detection of the serine palmitoytransferase (SPTLC-1) gene mutations for all studied groups. Results: There was predominance in male who developed more sever clinical manifestations than females. The disease onset was in the second and third decades of life. Patients with HSN 1 manifested reduced conduction velocity in both motor and sensory fibers of the lateral popliteal nerve (p< 0.01) however the ulnar nerve was spared (p = 0.61). Audiometry revealed bilateral partial nerve deafness in 3 cases and complete deafness in one case. Serum CRP and nucleosomes were significantly elevated in all patients as compared to the control group (p < 0.01). The genetic study revealed mutations of the SPTLC1 in all studied patients compared to the control group. Point mutation C133W was observed in younger patients having severe clinical manifestations with prominent leg ulceration, while the point mutation C133Y was observed in the older patients complaining of hearing loss. The mutation V144D was found in patients with mild clinical presentation having minimal ulceration and no hearing abnormalities. Conclusion: The SPTLC1 gene mutations play an important role in the pathogenesis and variability in clinical presentation of HSN1 disease.","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42744131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thyroglossal duct cyst is the most common upper neck midline lesion in children. Approximately 1% of thyroglossal duct cyst undergoes malignant transformation. Calcification which is a marker of malignancy almost always points out to papillary thyroid carcinoma. Benign case of calcified thyroglossal cyst maybe undiagnosed or under reported. We report a case of a 5 year old girl with a benign calcified thyroglossal duct cyst, a fourth case in world literature. Here the differences between a benign and malignant thyroglossal duct cyst are discussed.
{"title":"Benign calcified thyroglossal duct cyst, - defying the hallmark of papillary carcinoma, 4th case reported in literature","authors":"Aleev Sn, Lye Mh, Loo Cp, Marina Mb","doi":"10.31436/IMJM.V16I2.338","DOIUrl":"https://doi.org/10.31436/IMJM.V16I2.338","url":null,"abstract":"Thyroglossal duct cyst is the most common upper neck midline lesion in children. Approximately 1% of thyroglossal duct cyst undergoes malignant transformation. Calcification which is a marker of malignancy almost always points out to papillary thyroid carcinoma. Benign case of calcified thyroglossal cyst maybe undiagnosed or under reported. We report a case of a 5 year old girl with a benign calcified thyroglossal duct cyst, a fourth case in world literature. Here the differences between a benign and malignant thyroglossal duct cyst are discussed.","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45600168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdul Hadi Mohamed, A. Ralib, N. Abdullah, Ariff Osman, M. Nor
We report a sudden hypoxaemia during intubation and after extubation in patient was smoking few hour before surgery. The cause of his desaturation was not related to secretion in the upper airway but may be due to reduced oxygen tension in the body prior to surgery. We able to secure the airway and prevent prolonged of desaturation by intubating this patient during induction and after extubation. We excluded other cause of desaturation for example secretion, bronchospasm and also airway obstruction inn this case. We conclude that smoking cessation was necessary at long as possible even though in case of emergency to prevent potential hypoxaemia pre intubation and during extubation at the end of operation.
{"title":"Smoker Desaturation during General Anaesthesia: A Case Report","authors":"Abdul Hadi Mohamed, A. Ralib, N. Abdullah, Ariff Osman, M. Nor","doi":"10.31436/IMJM.V8I1.774","DOIUrl":"https://doi.org/10.31436/IMJM.V8I1.774","url":null,"abstract":"We report a sudden hypoxaemia during intubation and after extubation in patient was smoking few hour before surgery. The cause of his desaturation was not related to secretion in the upper airway but may be due to reduced oxygen tension in the body prior to surgery. We able to secure the airway and prevent prolonged of desaturation by intubating this patient during induction and after extubation. We excluded other cause of desaturation for example secretion, bronchospasm and also airway obstruction inn this case. We conclude that smoking cessation was necessary at long as possible even though in case of emergency to prevent potential hypoxaemia pre intubation and during extubation at the end of operation.","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41603895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Renal arteriovenous malformation (AVM) is a rare congenital anomaly of the urinary system. We present a patient with bilateral renal AVMs who presented with back pain and microscopic hematuria. This case highlights the importance of careful diagnostic work-up in the evaluation of upper tract hematuria. KEY WORDS: Renal AVM, Transarterial Embolization, Hematuria.
{"title":"Bilateral congenital renal arteriovenous malformation: A rare entity with uncommon presentation.","authors":"H. Radhiana, A. MohdShafie, Mohd Ariff Ma","doi":"10.31436/IMJM.V8I1.773","DOIUrl":"https://doi.org/10.31436/IMJM.V8I1.773","url":null,"abstract":"ABSTRACT Renal arteriovenous malformation (AVM) is a rare congenital anomaly of the urinary system. We present a patient with bilateral renal AVMs who presented with back pain and microscopic hematuria. This case highlights the importance of careful diagnostic work-up in the evaluation of upper tract hematuria. KEY WORDS: Renal AVM, Transarterial Embolization, Hematuria.","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48799814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Introduction: The aim of this study was to determine the differential patterns of mean duration of breastfeeding among mothers from slum areas in Rajshahi City, Bangladesh by using the multiple classification analysis (MCA). Materials and Methods: The data for this study was collected from mothers from slum areas of 8 different slums of Rajshahi City Corporation who had had at least one child at the time of interview. Results: We showed that the overall mean duration of breastfeeding was 24.66 months for all women, which may show considerable impact on fertility around slum areas in near future. Conclusion: Of all the selected variables in MCA, it was seen that the current age of the children and the body mass index of the respondents appear as the strongest important determinants of duration of breastfeeding and other variables play relatively less important role on the duration of breastfeeding. KEY WORDS: Breastfeeding, Slum mothers, Body mass index (BMI) and Multiple Classification Analysis (MCA).
摘要简介：本研究的目的是通过多元分类分析（MCA）确定孟加拉国拉杰沙希市贫民窟母亲平均母乳喂养时间的差异模式。材料和方法：本研究的数据收集自Rajshahi City Corporation 8个不同贫民窟的母亲，她们在接受采访时至少有一个孩子。结果：我们发现，所有妇女的总体平均母乳喂养时间为24.66个月，这可能在不久的将来对贫民窟地区的生育率产生相当大的影响。结论：在MCA的所有选定变量中，可以看出，儿童的当前年龄和受访者的体重指数似乎是母乳喂养持续时间的最重要决定因素，而其他变量对母乳喂养持续期的影响相对较小。关键词：母乳喂养，贫民窟的母亲，体重指数（BMI）和多分类分析（MCA）。
{"title":"Breastfeeding practices among slum mothers: a multivariate statistical analysis","authors":"Rafiqul I, Mahfuzar R, Mosfequr R, N. Im","doi":"10.31436/IMJM.V8I1.765","DOIUrl":"https://doi.org/10.31436/IMJM.V8I1.765","url":null,"abstract":"ABSTRACT Introduction: The aim of this study was to determine the differential patterns of mean duration of breastfeeding among mothers from slum areas in Rajshahi City, Bangladesh by using the multiple classification analysis (MCA). Materials and Methods: The data for this study was collected from mothers from slum areas of 8 different slums of Rajshahi City Corporation who had had at least one child at the time of interview. Results: We showed that the overall mean duration of breastfeeding was 24.66 months for all women, which may show considerable impact on fertility around slum areas in near future. Conclusion: Of all the selected variables in MCA, it was seen that the current age of the children and the body mass index of the respondents appear as the strongest important determinants of duration of breastfeeding and other variables play relatively less important role on the duration of breastfeeding. KEY WORDS: Breastfeeding, Slum mothers, Body mass index (BMI) and Multiple Classification Analysis (MCA).","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44650550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aoj Agboola, A. Deji-Agboola, K. Oritogun, A. Musa, T. Oyebadejo, B. Ayoade
ABSTRACT Background:Breast cancer is the leading cause of cancer mortality in women worldwide. This study was designed to assess the knowledge, attitude and practice of breast self examination (BSE) among female health workers in Sagamu. Methods: Questionnaire was used to obtain information such as demographic characteristics, knowledge of breast cancer, attitudes towards BSE and questions relating to practices of BSE from female health workers. Statistical analysis was carried out using descriptive statistics and Chi Square method. Results: The medical doctors had more knowledge about breast cancer than the nurses and laboratory scientists. The medical doctors (81.8%), laboratory scientists (56.5%) and the nurses (41.4%) knew the correct timing and frequency for performance of BSE. The monthly practice of BSE was very low among the nurses (30%), while only 68.2% of the doctors and 78.3% of laboratory scientist admitted carrying out BSE monthly. The doctors (68.2%), nurses (35.7%) and laboratory scientist (30.4%) started BSE below the age of 19 years. Conclusion: The results indicate that the nurses had poor attitude towards BSE and this affected their practice of BSE though they had knowledge. The finding that some of the female health workers did not practice BSE, suggests that there is a need for continuing education programs to change attitude and behaviour towards BSE. KEY WORDS: Breast Self Examination, Nurses, Doctors.
{"title":"KNOWLEDGE, ATTITUDE AND PRACTICE OF BREAST SELF EXAMINATION IN FEMALE HEALTH WORKERS IN OLABISI ONABANJO UNIVERSITY TEACHING HOSPITAL, SAGAMU, NIGERIA","authors":"Aoj Agboola, A. Deji-Agboola, K. Oritogun, A. Musa, T. Oyebadejo, B. Ayoade","doi":"10.31436/IMJM.V8I1.762","DOIUrl":"https://doi.org/10.31436/IMJM.V8I1.762","url":null,"abstract":"ABSTRACT Background:Breast cancer is the leading cause of cancer mortality in women worldwide. This study was designed to assess the knowledge, attitude and practice of breast self examination (BSE) among female health workers in Sagamu. Methods: Questionnaire was used to obtain information such as demographic characteristics, knowledge of breast cancer, attitudes towards BSE and questions relating to practices of BSE from female health workers. Statistical analysis was carried out using descriptive statistics and Chi Square method. Results: The medical doctors had more knowledge about breast cancer than the nurses and laboratory scientists. The medical doctors (81.8%), laboratory scientists (56.5%) and the nurses (41.4%) knew the correct timing and frequency for performance of BSE. The monthly practice of BSE was very low among the nurses (30%), while only 68.2% of the doctors and 78.3% of laboratory scientist admitted carrying out BSE monthly. The doctors (68.2%), nurses (35.7%) and laboratory scientist (30.4%) started BSE below the age of 19 years. Conclusion: The results indicate that the nurses had poor attitude towards BSE and this affected their practice of BSE though they had knowledge. The finding that some of the female health workers did not practice BSE, suggests that there is a need for continuing education programs to change attitude and behaviour towards BSE. KEY WORDS: Breast Self Examination, Nurses, Doctors.","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47882827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Left ventricular non-compaction cardiomyopathy (LVNC) is a rare congenital cardiomyopathy, which is characterized by hypertrabeculations and deep recesses of the left ventricle. A patient could be asymptomatic or presented with common manifestations, including reduced systolic function, arrhythmia, thromboembolic events and heart failure. The rarity of the condition as well as lack of proper assessment has probably led to this condition to be largely underdiagnosed or unrecognized. A 23-year-old lady had collapsed at home thirty one days after delivering her first child. She had a history of goitre diagnosed a year ago and noted to be fairly well throughout the pregnancy. Post mortem findings showed increased trabeculations of the left ventricle. Further history was obtained after the procedure, revealing symptoms such as syncopal attacks and bilateral lower limb weakness dated back as far as five years prior to her sudden demise. These features were in keeping with hypotension hypoperfusion effects resulted from reduced systolic function and decreased ejection fraction, as a result of left ventricular dysfunction. While LVNC remains a rare type of disease, we would like to highlight the importance of a good anamnesis. It may help to uncover some uncommon pathology such as this heart disease, thus warranting an appropriate cardiac imaging to be engaged to clinch the primary diagnosis.
{"title":"Maternal death and isolated left ventricular non-compaction cardiomyopathy","authors":"R. Rahimi, M. Shahidan, K. Thanikasalam","doi":"10.31436/IMJM.V16I2.340","DOIUrl":"https://doi.org/10.31436/IMJM.V16I2.340","url":null,"abstract":"Left ventricular non-compaction cardiomyopathy (LVNC) is a rare congenital cardiomyopathy, which is characterized by hypertrabeculations and deep recesses of the left ventricle. A patient could be asymptomatic or presented with common manifestations, including reduced systolic function, arrhythmia, thromboembolic events and heart failure. The rarity of the condition as well as lack of proper assessment has probably led to this condition to be largely underdiagnosed or unrecognized. A 23-year-old lady had collapsed at home thirty one days after delivering her first child. She had a history of goitre diagnosed a year ago and noted to be fairly well throughout the pregnancy. Post mortem findings showed increased trabeculations of the left ventricle. Further history was obtained after the procedure, revealing symptoms such as syncopal attacks and bilateral lower limb weakness dated back as far as five years prior to her sudden demise. These features were in keeping with hypotension hypoperfusion effects resulted from reduced systolic function and decreased ejection fraction, as a result of left ventricular dysfunction. While LVNC remains a rare type of disease, we would like to highlight the importance of a good anamnesis. It may help to uncover some uncommon pathology such as this heart disease, thus warranting an appropriate cardiac imaging to be engaged to clinch the primary diagnosis.","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48602120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Introduction: In Klang, a district in the state of Selangor in Peninsular Malaysia, the effects of westernization and urbanization in recent years have had an impact on infant feeding. The objective of this study was to evaluate the practice, knowledge and attitude to breastfeeding and to assess factors associated with breastfeeding among women in Klang, Malaysia. Materials & Methods: A cross-sectional study was carried out between June and October 2006 involving 220 women with infants aged six months from two randomly selected health clinics were selected and interviewed. Data on socio-demographic, infant factors, infant feeding in the first six months of life, knowledge and attitude towards breastfeeding were collected. Results: Exclusive breastfeeding was reported by 32.8%, mixed feeding was reported by 14.5% and infant formula feeding was reported by 52.7% of the respondents. Chinese women were more likely not to practice exclusive breastfeeding compared to Malay women (odds ratio 18.27, 95% CI: 3.95 , 84.54) while working women were more likely not to practice exclusive breastfeeding compared to non working women (odds ratio 3.75, 95% CI: 1.64 , 8.55). Positive association with not exclusive breastfeeding included women with high household income and women with male infants. Malaysian women had a positive attitude but work place and short maternity leave had a negative impact on breastfeeding. Conclusion: Women of Chinese ethnicity, working, from high family income and with male infants were less likely to exclusively breastfeed. Adopting facilitatory measures at hospitals and work place could increase the rate of exclusive breastfeeding. KEYWORDS: Exclusive breastfeeding, KAP, Malaysia
{"title":"Knowledge, attitude and practice on breastfeeding in Klang, Malaysia","authors":"Tan Kl","doi":"10.31436/IMJM.V8I1.764","DOIUrl":"https://doi.org/10.31436/IMJM.V8I1.764","url":null,"abstract":"ABSTRACT Introduction: In Klang, a district in the state of Selangor in Peninsular Malaysia, the effects of westernization and urbanization in recent years have had an impact on infant feeding. The objective of this study was to evaluate the practice, knowledge and attitude to breastfeeding and to assess factors associated with breastfeeding among women in Klang, Malaysia. Materials & Methods: A cross-sectional study was carried out between June and October 2006 involving 220 women with infants aged six months from two randomly selected health clinics were selected and interviewed. Data on socio-demographic, infant factors, infant feeding in the first six months of life, knowledge and attitude towards breastfeeding were collected. Results: Exclusive breastfeeding was reported by 32.8%, mixed feeding was reported by 14.5% and infant formula feeding was reported by 52.7% of the respondents. Chinese women were more likely not to practice exclusive breastfeeding compared to Malay women (odds ratio 18.27, 95% CI: 3.95 , 84.54) while working women were more likely not to practice exclusive breastfeeding compared to non working women (odds ratio 3.75, 95% CI: 1.64 , 8.55). Positive association with not exclusive breastfeeding included women with high household income and women with male infants. Malaysian women had a positive attitude but work place and short maternity leave had a negative impact on breastfeeding. Conclusion: Women of Chinese ethnicity, working, from high family income and with male infants were less likely to exclusively breastfeed. Adopting facilitatory measures at hospitals and work place could increase the rate of exclusive breastfeeding. KEYWORDS: Exclusive breastfeeding, KAP, Malaysia","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41706455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In children, most cases of optic neuritis are immune-related. Less frequently, it may also be due to demyelinating disorders. Other secondary causes such as infection of adjacent structures or infiltration are even rarer. The occurrence of optic neuritis in children on chemotherapy also has not being extensively reported. We report a case of bilateral optic neuritis in a young girl with subacute visual loss after receiving systemic chemotherapy for embryonal ovarian carcinoma.
{"title":"Chemotherapy Related Optic Neuritis","authors":"Nurutdinov As, Jemaima Ch, F. Ismail, Safinaz Mk","doi":"10.31436/IMJM.V16I2.342","DOIUrl":"https://doi.org/10.31436/IMJM.V16I2.342","url":null,"abstract":"In children, most cases of optic neuritis are immune-related. Less frequently, it may also be due to demyelinating disorders. Other secondary causes such as infection of adjacent structures or infiltration are even rarer. The occurrence of optic neuritis in children on chemotherapy also has not being extensively reported. We report a case of bilateral optic neuritis in a young girl with subacute visual loss after receiving systemic chemotherapy for embryonal ovarian carcinoma.","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47066070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Cervical vertebral osteomyelitis is rare. While an early and correct diagnosis is critical to prevent catastrophic neurological injury, the diagnosis of cervical vertebral osteomyelitis is often difficult because of its rarity and variable symptoms. We present a case of C1 and C2 vertebrae osteomyelitis with a misleading presentation and its fatal outcome. KEYWORDS: Cervical spine, osteomyelitis, spinal infection
{"title":"C1 and C2 vertebrae osteomyelitis: a misleading presentation leading to a fatal outcome","authors":"H. Radhiana, J. WinMarSalmah","doi":"10.31436/IMJM.V8I1.772","DOIUrl":"https://doi.org/10.31436/IMJM.V8I1.772","url":null,"abstract":"ABSTRACT Cervical vertebral osteomyelitis is rare. While an early and correct diagnosis is critical to prevent catastrophic neurological injury, the diagnosis of cervical vertebral osteomyelitis is often difficult because of its rarity and variable symptoms. We present a case of C1 and C2 vertebrae osteomyelitis with a misleading presentation and its fatal outcome. KEYWORDS: Cervical spine, osteomyelitis, spinal infection","PeriodicalId":53575,"journal":{"name":"International Medical Journal Malaysia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46355051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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