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Different treatment modalities and their impact on outcomes in severe rigid scoliosis: a systematic review and pooled data meta-analysis 不同的治疗方式及其对严重刚性脊柱侧凸预后的影响:一项系统综述和汇总数据荟萃分析
Q2 Medicine Pub Date : 2025-12-01 DOI: 10.1016/j.jcot.2025.103295
Syed Ifthekar , Deepankar Satapathy , Kaustubh Ahuja , Samarth Mittal , Siddharth Sekhar Sethy , Pankaj Kandwal

Background

Severe rigid scoliosis is a stiff and complex three-dimensional deformity. The children presenting with severe scoliosis need to be timely treated to prevent further deterioration of the curves and physiological function. The goals of treatment include to stop the progression of the curve, restore the spinal alignment, prevent neurological deterioration or improve the neurology if it is already deteriorated, improvement of pulmonary function and improve cosmetic outcomes. The various surgical options are one stage correction with osteotomies, posterior only approach, staged anterior release and posterior approach, pre-operative optimization by halo traction followed by posterior fusion and temporary internal distraction.

Method

The study protocol was published in PROSPERO with the ID CRD420251046131.Studies with participants diagnosed with severe rigid scoliosis who were operated and reporting the baseline values and correction of the scoliosis at follow-up were included. Studies mentioning the type of procedure and complications associated with the procedure were also included. Studies dealing with exclusive kyphosis, infective deformities, porcine models, adult degenerative lumbar scoliosis and those that did not give details about the scoliosis correction were excluded.

Results

A total of Seventy-Five studies were included with 2314 patients. Both neurological and non-neurological complications were significantly more likely in osteotomy compared to halo traction followed by definitive surgery. The difference was very significant in neurological complications (RR∼3.76, 95 % CI = 2.52–5.60).

Conclusion

Among the various strategies employed to treat severe rigid scoliosis, Spinal Osteotomy techniques had the highest rates of neurological and non-neurological complications. All the techniques described like halo traction, osteotomy and staged procedures gave a good curve correction in severe rigid scoliosis.
背景:重度刚性脊柱侧凸是一种僵硬复杂的三维畸形。出现严重脊柱侧凸的患儿需要及时治疗,防止脊柱曲度和生理功能进一步恶化。治疗的目标包括停止弯曲的进展,恢复脊柱的排列,防止神经系统恶化或改善神经系统,如果它已经恶化,改善肺功能和改善美容效果。各种手术选择包括一期截骨矫正,单纯后路入路,分阶段前路释放和后路入路,术前通过晕轮牵引进行优化,然后进行后路融合和暂时内撑开。研究方案发表在《普洛斯彼罗》杂志上,编号CRD420251046131。被诊断为严重僵硬性脊柱侧凸的参与者接受了手术,并在随访中报告了脊柱侧凸的基线值和矫正情况。涉及手术类型和手术并发症的研究也包括在内。排除了排他性脊柱后凸、感染性畸形、猪模型、成人退行性腰椎侧凸以及未提供脊柱侧凸矫正细节的研究。结果共纳入75项研究,2314例患者。截骨术中神经系统和非神经系统并发症的发生率明显高于halo牵引后的最终手术。神经系统并发症的差异非常显著(RR ~ 3.76, 95% CI = 2.52 ~ 5.60)。结论在治疗重度刚性脊柱侧凸的方法中,脊柱截骨术的神经和非神经并发症发生率最高。所有描述的技术,如光晕牵引,截骨术和分阶段手术都能很好地矫正严重的刚性脊柱侧凸。
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引用次数: 0
Surgical techniques for the management of severe rigid scoliosis 治疗重度刚性脊柱侧凸的外科技术
Q2 Medicine Pub Date : 2025-12-01 DOI: 10.1016/j.jcot.2025.103293
Stephane Owusu-Sarpong , Tejas Subramanian , Han Jo Kim
Severe rigid scoliosis presents some unique challenges with respect to surgical techniques and complications. Anterior and posterior techniques, as well as combined approaches, can be employed for the surgical management of this condition. The purpose of this article is to describe severe rigid scoliosis as an entity and to delve into the surgical tools that may be utilized for the treatment of this complex condition. Specific techniques are presented in detail, including preoperative halo-gravity/halo-pelvic traction, as well as correction maneuvers such as anterior release, thoracoplasty, concave rib osteotomy, and posterior vertebral column resection. Preoperative halo traction improves curve flexibility and pulmonary status, anterior release and concave rib osteotomy enhance mobilization, thoracoplasty addresses rib prominence, and posterior vertebral column resection provides powerful single-stage correction. Collectively, these techniques expand surgical options and mitigate neurologic and cardiopulmonary risks in severe rigid scoliosis.
严重的刚性脊柱侧凸在手术技术和并发症方面提出了一些独特的挑战。前后路技术以及联合入路可用于这种情况的手术治疗。本文的目的是描述严重的刚性脊柱侧凸作为一个实体,并深入研究可能用于治疗这种复杂情况的手术工具。详细介绍了具体的技术,包括术前halo-gravity/halo-骨盆牵引,以及矫正操作,如前路松解、胸廓成形术、凹肋骨截骨术和后路脊柱切除术。术前halo牵引改善弯曲柔韧性和肺部状态,前路松解和凹肋截骨增强活动能力,胸廓成形术解决肋骨突出问题,后路脊柱切除术提供强大的单期矫正。总的来说,这些技术扩大了手术选择,减轻了严重刚性脊柱侧凸的神经和心肺风险。
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引用次数: 0
Impact of posterior tibial slope on functional outcomes after mobile-bearing total knee arthroplasty 胫骨后倾角对可移动全膝关节置换术后功能预后的影响
Q2 Medicine Pub Date : 2025-12-01 DOI: 10.1016/j.jcot.2025.103296
Tarun Jayakumar, Kushal Hippalgaonkar, Albin Savio, Chiranjeevi Thayi, AV.Gurava Reddy

Background

Posterior tibial slope (PTS) is believed to influence range of motion (ROM) and functional outcomes after total knee arthroplasty (TKA), particularly in cruciate-retaining and posterior-stabilized designs. However, limited data exist on its impact in mobile-bearing systems. This study evaluated whether variations in PTS affect ROM and patient-reported outcome measures (PROMs) following mobile-bearing TKA using the Buechel-Pappas design.

Methods

This was a retrospective, single center cohort study on 359 patients who underwent cemented mobile-bearing TKA between 2018 and 2022, with a minimum follow-up of 2 years. Patients were stratified into three PTS categories: <4°, 4–7°, and >7° and analyzed. Functional outcomes were assessed using the Oxford Knee Score (OKS), Forgotten Joint Score (FJS), maximal knee ROM, and complications.

Results

Patient had a mean follow-up of 2.8 years (SD = 0.9) with a mean age was 61.3 (SD = 7.7) years. Baseline demographic characteristics were comparable between the 3 cohorts. Mean postoperative ROM improved significantly from 75.2° to 95.3°, and mean OKS from 16.2 to 34.5 (p < 0.001). However, no significant differences in ROM, OKS, or FJS were observed between PTS groups (p > 0.05). Analysis of change in PTS between pre-operative to post-operative showed no significant difference. ROC analyses and logistic regression demonstrated poor predictive ability of PTS for functional outcomes.

Conclusion

Variations in posterior tibial slope within typical clinical ranges (<4°, 4–7°, >7°), as well as the degree of change in slope achieved from preoperative to postoperative alignment, did not significantly affect postoperative range of motion or patient-reported outcomes following mobile-bearing total knee arthroplasty.
背景:胫骨后斜度(PTS)被认为会影响全膝关节置换术(TKA)后的活动范围(ROM)和功能结果,特别是在交叉关节保留和后稳定设计中。然而,关于其对移动轴承系统影响的数据有限。本研究使用buecheler - pappas设计评估了PTS的变化是否会影响移动轴承TKA后的ROM和患者报告的结果测量(PROMs)。方法:本研究是一项回顾性、单中心队列研究,研究对象为359例在2018年至2022年间接受骨水泥移动轴承TKA的患者,随访时间至少为2年。将患者分为4°、4 - 7°和7°三种PTS类型并进行分析。使用牛津膝关节评分(OKS)、遗忘关节评分(FJS)、最大膝关节ROM和并发症评估功能结果。结果患者平均随访2.8年(SD = 0.9),平均年龄61.3岁(SD = 7.7)。基线人口统计学特征在三个队列之间具有可比性。术后平均ROM从75.2°显著改善到95.3°,平均OKS从16.2°显著改善到34.5°(p < 0.001)。然而,两组间ROM、OKS和FJS均无显著差异(p > 0.05)。术前与术后PTS变化分析无明显差异。ROC分析和logistic回归显示PTS对功能预后的预测能力较差。结论在典型临床范围内(4°,4 - 7°,7°)胫骨后坡的变化,以及术前至术后对齐时胫骨后坡的变化程度,对活动负重全膝关节置换术术后的活动范围或患者报告的结果没有显著影响。
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引用次数: 0
Revisiting the ACL reconstruction rehabilitation algorithm: A gait analysis study 重新审视ACL重建康复算法:步态分析研究
Q2 Medicine Pub Date : 2025-11-30 DOI: 10.1016/j.jcot.2025.103291
Champak Roy, Vineet Kumar, Devashish Chhutani, Prabhat Kumar, Pankaj Aggarwal, Mohd Ammar Aslam

Background

Anterior cruciate ligament (ACL) injuries are common among young adults, often resulting in knee instability and impacting quality of life. Despite advances in surgical techniques and rehabilitation, patients experience persistent quadriceps weakness, altered gait patterns, and increased risk of osteoarthritis.

Methods

This 1-year prospective cohort study investigated knee joint stability and gait patterns in 45 patients within one-year post-ACL reconstruction. Gait analysis was performed using a six-infrared camera system and two force plates. Lysholm knee scoring scale was used to evaluate knee function.

Results

The study's results showed that among 45 ACL reconstruction patients, majority were males (97.78 %) aged 25–29 (33.33 %), with high knee function (average Lysholm score: 95.33 ± 3.47). Gait analysis revealed altered patterns with reduced trunk movement, deviations from normal stride parameters in both limbs. Trunk obliquity and tilt were lower than normal, knee valgus-varus alignment was lower in both limbs, with the operated limb having slightly higher alignment. Knee flexion-extension was lower in the operated limb. The study highlighted altered gait patterns and reduced trunk movement in ACL reconstruction patients.

Conclusion

This study emphasizes the importance of comprehensive rehabilitation programs for ACL reconstruction patients, focusing on hip strengthening exercises to restore optimal gait patterns. Tailored rehabilitation plans with hip physiotherapy can improve hip muscle strength and symmetry, enhancing patient care and long-term success. By integrating these insights, healthcare professionals can provide more effective care, improving patients' quality of life and functional abilities.
背景前交叉韧带(ACL)损伤在年轻人中很常见,通常导致膝关节不稳定并影响生活质量。尽管手术技术和康复技术有所进步,但患者仍会经历持续性股四头肌无力、步态模式改变和骨关节炎风险增加。方法这项为期1年的前瞻性队列研究调查了45例前交叉韧带重建术后1年内的膝关节稳定性和步态模式。步态分析采用六红外摄像系统和两个测力板。采用Lysholm膝关节评分量表评估膝关节功能。结果45例ACL重建患者中,25 ~ 29岁(33.33%)男性居多(97.78%),膝关节功能较高(平均Lysholm评分95.33±3.47)。步态分析显示改变的模式与减少躯干运动,偏离正常的跨步参数在四肢。躯干的倾斜度和倾斜度均低于正常水平,两肢膝关节外翻对准度较低,手术肢体稍高。手术肢体膝关节屈伸较低。该研究强调了前交叉韧带重建患者步态模式的改变和躯干运动的减少。结论本研究强调了前交叉韧带重建患者综合康复计划的重要性,重点是髋关节强化训练以恢复最佳步态模式。量身定制的康复计划与髋关节物理治疗可以改善髋关节肌肉力量和对称性,提高患者护理和长期成功。通过整合这些见解,医疗保健专业人员可以提供更有效的护理,提高患者的生活质量和功能能力。
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引用次数: 0
Meniscectomy before total knee arthroplasty increases the risk of all-cause revision and revision for infection: A national database analysis 全膝关节置换术前半月板切除术增加全因翻修和感染翻修的风险:一项国家数据库分析
Q2 Medicine Pub Date : 2025-11-30 DOI: 10.1016/j.jcot.2025.103292
Cole R. Johnson, Khaled A. Elmenawi, Ahmed K. Emara, Benjamin E. Jevnikar, Matthew E. Deren, Nicolas S. Piuzzi

Background

Arthroscopic meniscectomy (AM) is a common procedure in middle-aged adults with degenerative meniscal tears. As many of these patients eventually require total knee arthroplasty (TKA), concerns have emerged regarding the potential impact of prior AM on TKA outcomes. This study evaluated whether a history of ipsilateral AM is associated with increased short- and mid-term complications following TKA.

Methods

Using the PearlDiver national database, adult patients who underwent primary TKA for osteoarthritis between 2016 and 2022 with 1-year of follow-up and laterality available were identified (n = 1,152,444). Patients with prior ipsilateral AM were matched 1:1 to controls without prior AM based on age, sex, comorbidities, and year of surgery (n = 40,341 per group). Multivariate logistic regression was used to evaluate 90-day healthcare utilization (emergency department visits, reoperations, and readmissions) and 1- and 2-year revision risks (all-cause, septic, and aseptic).

Results

Approximately 3.5 % of TKA patients had prior AM. Patients with prior AM had significantly higher rates of 90-day emergency department visits (OR, 1.23; 95 % CI, 1.18–1.29), reoperations (OR, 2.10; 95 % CI, 1.95–2.27), and readmissions (OR, 1.43; 95 % CI, 1.32–1.55) (all p < 0.001). At 1-year post-TKA, these patients had increased odds of all-cause revision (OR, 2.47), revision for PJI (OR, 2.15), and aseptic revision (OR, 2.62). These risks remained elevated at 2 years: all-cause revision (OR, 2.83), revision for PJI (OR, 2.33), and aseptic revision (OR, 3.06) (all p < 0.001).

Conclusions

Prior ipsilateral AM is associated with significantly increased risks of short- and mid-term complications following primary TKA, including reoperations, readmissions, and both septic and aseptic revisions. These findings highlight the need for careful patient counseling and surgical planning in patients with a history of meniscectomy.

Level of evidence

Level III; Retrospective cohort study.
背景:腹腔镜半月板切除术(AM)是中年人退行性半月板撕裂的常见手术。由于许多患者最终需要全膝关节置换术(TKA),因此人们开始关注先前AM对TKA结果的潜在影响。本研究评估了同侧AM病史是否与TKA后短期和中期并发症的增加有关。方法使用PearlDiver国家数据库,确定2016年至2022年期间因骨关节炎接受原发性TKA的成年患者,随访1年,可获得侧位(n = 1,152,444)。有同侧AM病史的患者与没有AM病史的对照组根据年龄、性别、合并症和手术年份进行1:1匹配(每组n = 40,341)。使用多变量logistic回归评估90天医疗保健利用(急诊科就诊、再手术和再入院)以及1年和2年翻修风险(全因、脓毒症和无菌)。结果约3.5%的TKA患者既往有AM。有AM病史的患者90天急诊科就诊率(OR, 1.23; 95% CI, 1.18-1.29)、再手术率(OR, 2.10; 95% CI, 1.95-2.27)和再入院率(OR, 1.43; 95% CI, 1.32-1.55)显著较高(均p <; 0.001)。在tka后1年,这些患者的全因翻修(OR, 2.47)、PJI翻修(OR, 2.15)和无菌翻修(OR, 2.62)的几率增加。这些风险在2年时仍然升高:全因修正(OR, 2.83)、PJI修正(OR, 2.33)和无菌修正(OR, 3.06)(均p <; 0.001)。结论先前的同侧AM与原发性TKA后短期和中期并发症的风险显著增加相关,包括再手术、再入院以及脓毒性和无菌性翻修。这些发现强调了对有半月板切除术史的患者进行仔细的患者咨询和手术计划的必要性。证据等级:III级;回顾性队列研究。
{"title":"Meniscectomy before total knee arthroplasty increases the risk of all-cause revision and revision for infection: A national database analysis","authors":"Cole R. Johnson,&nbsp;Khaled A. Elmenawi,&nbsp;Ahmed K. Emara,&nbsp;Benjamin E. Jevnikar,&nbsp;Matthew E. Deren,&nbsp;Nicolas S. Piuzzi","doi":"10.1016/j.jcot.2025.103292","DOIUrl":"10.1016/j.jcot.2025.103292","url":null,"abstract":"<div><h3>Background</h3><div>Arthroscopic meniscectomy (AM) is a common procedure in middle-aged adults with degenerative meniscal tears. As many of these patients eventually require total knee arthroplasty (TKA), concerns have emerged regarding the potential impact of prior AM on TKA outcomes. This study evaluated whether a history of ipsilateral AM is associated with increased short- and mid-term complications following TKA.</div></div><div><h3>Methods</h3><div>Using the PearlDiver national database, adult patients who underwent primary TKA for osteoarthritis between 2016 and 2022 with 1-year of follow-up and laterality available were identified (n = 1,152,444). Patients with prior ipsilateral AM were matched 1:1 to controls without prior AM based on age, sex, comorbidities, and year of surgery (n = 40,341 per group). Multivariate logistic regression was used to evaluate 90-day healthcare utilization (emergency department visits, reoperations, and readmissions) and 1- and 2-year revision risks (all-cause, septic, and aseptic).</div></div><div><h3>Results</h3><div>Approximately 3.5 % of TKA patients had prior AM. Patients with prior AM had significantly higher rates of 90-day emergency department visits (OR, 1.23; 95 % CI, 1.18–1.29), reoperations (OR, 2.10; 95 % CI, 1.95–2.27), and readmissions (OR, 1.43; 95 % CI, 1.32–1.55) (all p &lt; 0.001). At 1-year post-TKA, these patients had increased odds of all-cause revision (OR, 2.47), revision for PJI (OR, 2.15), and aseptic revision (OR, 2.62). These risks remained elevated at 2 years: all-cause revision (OR, 2.83), revision for PJI (OR, 2.33), and aseptic revision (OR, 3.06) (all p &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>Prior ipsilateral AM is associated with significantly increased risks of short- and mid-term complications following primary TKA, including reoperations, readmissions, and both septic and aseptic revisions. These findings highlight the need for careful patient counseling and surgical planning in patients with a history of meniscectomy.</div></div><div><h3>Level of evidence</h3><div>Level III; Retrospective cohort study.</div></div>","PeriodicalId":53594,"journal":{"name":"Journal of Clinical Orthopaedics and Trauma","volume":"72 ","pages":"Article 103292"},"PeriodicalIF":0.0,"publicationDate":"2025-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145797114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intra-articular and extra-articular malunion of proximal tibia: Assessment and management 胫骨近端关节内和关节外畸形愈合:评估和处理
Q2 Medicine Pub Date : 2025-11-24 DOI: 10.1016/j.jcot.2025.103279
Srinivas Kasha , Ranjith Kumar Yalamanchili , Rohit GPRK , Susmith Koneru , Anurag Gurram , Venkat Ravi Weera Athili
Proximal tibial malunions resulting from inappropriate reduction or neglected traumatic sequelae can significantly alter knee biomechanics and predispose the patients to pain, instability, and early post traumatic osteoarthritis (PTOA). Their management requires a detailed analysis of the fracture fragments, location of deformity and status of soft tissue. Accurate preoperative assessment including clinical evaluation, standing radiographs, long-leg scanogram, and 2D/3D CT scans are critical for identifying coronal, sagittal, rotational, and multiplanar deformities. Deformity analysis using malalignment tests and marking of the centre of rotation of angulation (CORA) guides surgical planning. Surgical management focus on correction of limb alignment, restoration of articular congruity and stable fixation. Intra-articular osteotomy is preferred for depression or split-depression injuries, while extra-articular osteotomies address coronal or sagittal plane malalignment. Bicondylar and combined deformities may require dual approaches, and a tibial tubercle (TT) osteotomy might be needed to access and correct deformities, when CORA is close to TT. The biological potential of the osteotomy site, soft tissue condition, and bone quality must be considered when planning fixation. Internal fixation devices including bone graft is only suitable in cases with good soft tissue cover. A circular external fixator is preferred when gradual correction is required and particularly in cases where soft tissues are unsuitable for internal fixation. Mechanical axis should be restored as soon as it is safe to do so to prevent or slow the progression of PTOA. In this article we discuss classification and management strategies for proximal tibial malunions, emphasizing meticulous preoperative planning, surgical approach selection, surgical strategies to optimise functional outcomes and preserve the native joint.
不适当复位或忽视创伤后遗症导致的胫骨近端畸形愈合可显著改变膝关节生物力学,使患者易出现疼痛、不稳定和早期创伤后骨关节炎(PTOA)。他们的治疗需要详细分析骨折碎片,畸形的位置和软组织的状态。准确的术前评估,包括临床评估、站立x线片、长腿扫描和2D/3D CT扫描,对于识别冠状、矢状、旋转和多平面畸形至关重要。畸形分析使用不对准测试和标记成角旋转中心(CORA)指导手术计划。手术治疗的重点是纠正肢体的直线,恢复关节的一致性和稳定的固定。关节内截骨术是治疗凹陷性或分裂性凹陷性损伤的首选方法,而关节外截骨术则是治疗冠状面或矢状面排列异常。双髁和合并畸形可能需要双重入路,当CORA接近胫骨结节(TT)时,可能需要胫骨结节截骨术来进入和纠正畸形。在计划固定时,必须考虑截骨部位的生物学潜能、软组织状况和骨质量。包括骨移植在内的内固定装置只适用于软组织覆盖良好的情况。当需要逐渐矫正时,特别是当软组织不适合内固定时,首选圆形外固定架。机械轴应在安全的情况下尽快恢复,以防止或减缓pta的进展。在这篇文章中,我们讨论胫骨近端畸形愈合的分类和治疗策略,强调细致的术前计划,手术入路的选择,手术策略以优化功能结果和保留原关节。
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引用次数: 0
Weekend surgery is associated with increased use of hemiarthroplasty for displaced femoral neck fractures: A propensity-matched study 周末手术与移位股骨颈骨折半关节置换术的使用增加相关:一项倾向匹配的研究
Q2 Medicine Pub Date : 2025-11-21 DOI: 10.1016/j.jcot.2025.103275
Stephen C. Moye , Austin T. Gregg , Thirushan Wignakumar , Adam N. Musick , Antonia F. Chen , Nishant Suneja

Background

Displaced femoral neck fractures in older adults are commonly treated with either hemiarthroplasty (HA) or total hip arthroplasty (THA), with the choice influenced by patient characteristics, surgeon training, and logistical factors. Prior international studies suggest THA is more often performed on weekdays and by arthroplasty-trained surgeons, but it is unclear whether similar patterns exist in the United States. This study examines whether weekend surgery affects the choice between HA and THA after adjusting for patient and surgeon-specific factors.

Methods

Design: Retrospective cohort.
Setting: Two Level 1 Trauma Centers.
Patient Selection Criteria: Adult patients with displaced femoral neck fractures (2001–2023) treated with HA or THA.
Outcome Measures and Comparisons: The primary outcome was the relative proportion of HA versus THA performed on weekends versus weekdays. Secondary outcomes included perioperative factors associated with weekend surgery.

Results

Among 1947 cases, propensity matching yielded two well-balanced cohorts of 497 cases. Before matching, HA patients were older (80.4 vs. 70.9 years, p < 0.0001), had lower BMI (24.6 vs. 25.4 kg/m2, p = 0.002), and had a higher Elixhauser Comorbidity Index (25.5 vs. 15.3, p < 0.0001). Surgeon subspecialty training differed between the cohorts and more experienced surgeons were more likely to choose THA (15.1 years vs. 13.0 years, p = 0.0004). After matching, weekend surgery was associated with higher HA rates (24.7 % vs. 18.7 %, p = 0.021), despite appropriately balanced patient and surgeon characteristics.

Conclusions

Weekend surgery is associated with higher rates of HA over THA in displaced FNFs, independent of patient and surgeon characteristics. These findings suggest potential system-level factors influencing surgical decision-making and highlight the need for further investigation into resource allocation, cognitive biases, and perioperative workflows.

Mesh terms

Arthroplasty, Replacement, Hip; Hip Fractures; Practice Patterns, Physician's; Propensity Score.

Level of evidence

Therapeutic Level IV.
背景:老年人移位性股骨颈骨折通常采用半髋关节置换术(HA)或全髋关节置换术(THA)治疗,其选择受患者特点、外科医生培训和后勤因素的影响。先前的国际研究表明,人工髋关节置换术更常在工作日由接受过关节置换术培训的外科医生进行,但尚不清楚在美国是否存在类似的模式。本研究考察了在调整患者和外科医生的特定因素后,周末手术是否会影响HA和THA之间的选择。方法设计:回顾性队列研究。环境:两个一级创伤中心。患者选择标准:接受HA或THA治疗的成年移位型股骨颈骨折患者(2001-2023)。结果测量和比较:主要结果是在周末和工作日进行HA和THA的相对比例。次要结局包括与周末手术相关的围手术期因素。结果在1947例病例中,倾向匹配得到两组均衡的497例病例。配对前,HA患者年龄较大(80.4 vs. 70.9岁,p <; 0.0001),BMI较低(24.6 vs. 25.4 kg/m2, p = 0.002),Elixhauser共病指数较高(25.5 vs. 15.3, p <; 0.0001)。外科医生亚专科培训在队列之间存在差异,经验丰富的外科医生更有可能选择THA(15.1年vs 13.0年,p = 0.0004)。匹配后,周末手术与更高的HA率相关(24.7 % vs. 18.7 %,p = 0.021),尽管适当平衡了患者和外科医生的特征。结论:与患者和外科医生的特点无关,周末手术与移位的fnf中HA的发生率高于THA相关。这些发现提示了影响手术决策的潜在系统层面因素,并强调了对资源分配、认知偏差和围手术期工作流程进行进一步调查的必要性。补片术语:髋关节置换;髋部骨折;医师执业模式;倾向分数。证据水平:治疗性四级。
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引用次数: 0
Clinical and functional outcomes of neo-adjuvant zoledronic acid therapy and valgus osteotomy in proximal femoral fibrous dysplasia 新辅助唑来膦酸治疗和外翻截骨治疗股骨近端纤维发育不良的临床和功能结果
Q2 Medicine Pub Date : 2025-11-20 DOI: 10.1016/j.jcot.2025.103277
Nitish Jagdish Jyoti , Pon Aravindhan, Ritvik Janardhanan, Dyuti Deepta Rano, Love Kapoor, Shah Alam Khan

Background

Fibrous dysplasia (FD) is characterised by structurally weak bone due to disorganized fibro-osseous matrix, leading to pain, deformities and pathological fractures. While traditional treatments like curettage and bone grafting are ineffective due to graft resorption and lesion persistence, intramedullary fixation is currently preferred method to prevent recurrent deformities and fractures. This study aimed to evaluate the clinical and functional outcomes of neo-adjuvant zoledronic acid (ZA) therapy combined with valgus osteotomy in proximal femoral FD, and to assess changes in neck-shaft angle (NSA) and limb length discrepancy (LLD).

Methods

This single centre, retrospective study included eight patients with proximal femoral monostotic/polyostotic FD treated between January 2021 and December 2023. All patients received three doses of intravenous ZA at 4-week intervals, followed by valgus osteotomy performed 8 weeks after the final ZA dose. Pre- and post-operative NSA and LLD were recorded and compared. Functional outcomes were assessed using the modified Guille criteria.

Results

The mean age was 21.8 ± 6.68 years. Three patients had monostotic and 5 had polyostotic FD. Mean follow-up was 24.5 ± 6.4 months. All patients experienced pain relief post-ZA without serious adverse events, although only 2 showed radiological improvement. The mean modified Guille score improved from 3.5 ± 1.51 to 8.25 ± 1.48 (p = 0.01). The mean NSA improved from 100.75 ± 17.05° to 125.75 ± 8.31° (p = 0.044) and LLD reduced from 1.93 ± 0.72 cm to 0.93 ± 0.49 cm (p < 0.001). Union was achieved in all cases with a mean healing time of 6.25 ± 1.66 months.

Conclusion

Combining neo-adjuvant ZA therapy and valgus osteotomy offers significant functional improvement and deformity correction in proximal femoral FD. While ZA offers consistent pain relief, its radiological impact remains variable. Valgus osteotomy, stabilized with intra- or extramedullary fixation remains a valuable technique for managing FD-associated deformities. Further prospective studies are warranted to refine treatment protocols and validate long-term outcomes.
纤维发育不良(FD)的特征是由于纤维-骨基质紊乱导致骨结构薄弱,导致疼痛、畸形和病理性骨折。由于移植物吸收和病变持续存在,传统的治疗方法如刮痧和植骨是无效的,髓内固定是目前预防复发性畸形和骨折的首选方法。本研究旨在评价新辅助唑来膦酸(ZA)联合外翻截骨治疗股骨近端FD的临床和功能结果,并评估颈轴角(NSA)和肢体长度差异(LLD)的变化。方法本研究为单中心回顾性研究,纳入了2021年1月至2023年12月期间接受治疗的8例股骨近端单侧/多侧FD患者。所有患者每隔4周接受三次静脉注射ZA,最后一次ZA给药后8周进行外翻截骨。记录术前、术后NSA和LLD并进行比较。功能结果采用改良的吉尔标准进行评估。结果患者平均年龄21.8±6.68岁。单纯性FD 3例,多骨性FD 5例。平均随访24.5±6.4个月。所有患者术后疼痛缓解,无严重不良事件,仅有2例影像学改善。改良吉尔平均评分由3.5±1.51分提高至8.25±1.48分(p = 0.01)。平均NSA从100.75±17.05°提高到125.75±8.31°(p = 0.044), LLD从1.93±0.72 cm降低到0.93±0.49 cm (p < 0.001)。所有病例均愈合,平均愈合时间为6.25±1.66个月。结论新辅助ZA联合外翻截骨术对股骨近端FD有明显的功能改善和畸形矫正作用。虽然ZA提供持续的疼痛缓解,但其放射学影响仍然是可变的。外翻截骨,髓内或髓外固定稳定仍然是治疗fd相关畸形的一种有价值的技术。需要进一步的前瞻性研究来完善治疗方案并验证长期结果。
{"title":"Clinical and functional outcomes of neo-adjuvant zoledronic acid therapy and valgus osteotomy in proximal femoral fibrous dysplasia","authors":"Nitish Jagdish Jyoti ,&nbsp;Pon Aravindhan,&nbsp;Ritvik Janardhanan,&nbsp;Dyuti Deepta Rano,&nbsp;Love Kapoor,&nbsp;Shah Alam Khan","doi":"10.1016/j.jcot.2025.103277","DOIUrl":"10.1016/j.jcot.2025.103277","url":null,"abstract":"<div><h3>Background</h3><div>Fibrous dysplasia (FD) is characterised by structurally weak bone due to disorganized fibro-osseous matrix, leading to pain, deformities and pathological fractures. While traditional treatments like curettage and bone grafting are ineffective due to graft resorption and lesion persistence, intramedullary fixation is currently preferred method to prevent recurrent deformities and fractures. This study aimed to evaluate the clinical and functional outcomes of neo-adjuvant zoledronic acid (ZA) therapy combined with valgus osteotomy in proximal femoral FD, and to assess changes in neck-shaft angle (NSA) and limb length discrepancy (LLD).</div></div><div><h3>Methods</h3><div>This single centre, retrospective study included eight patients with proximal femoral monostotic/polyostotic FD treated between January 2021 and December 2023. All patients received three doses of intravenous ZA at 4-week intervals, followed by valgus osteotomy performed 8 weeks after the final ZA dose. Pre- and post-operative NSA and LLD were recorded and compared. Functional outcomes were assessed using the modified Guille criteria.</div></div><div><h3>Results</h3><div>The mean age was 21.8 ± 6.68 years. Three patients had monostotic and 5 had polyostotic FD. Mean follow-up was 24.5 ± 6.4 months. All patients experienced pain relief post-ZA without serious adverse events, although only 2 showed radiological improvement. The mean modified Guille score improved from 3.5 ± 1.51 to 8.25 ± 1.48 (p = 0.01). The mean NSA improved from 100.75 ± 17.05° to 125.75 ± 8.31° (p = 0.044) and LLD reduced from 1.93 ± 0.72 cm to 0.93 ± 0.49 cm (p &lt; 0.001). Union was achieved in all cases with a mean healing time of 6.25 ± 1.66 months.</div></div><div><h3>Conclusion</h3><div>Combining neo-adjuvant ZA therapy and valgus osteotomy offers significant functional improvement and deformity correction in proximal femoral FD. While ZA offers consistent pain relief, its radiological impact remains variable. Valgus osteotomy, stabilized with intra- or extramedullary fixation remains a valuable technique for managing FD-associated deformities. Further prospective studies are warranted to refine treatment protocols and validate long-term outcomes.</div></div>","PeriodicalId":53594,"journal":{"name":"Journal of Clinical Orthopaedics and Trauma","volume":"72 ","pages":"Article 103277"},"PeriodicalIF":0.0,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computed tomography versus plain radiography in the Mitsuzawa classification for severe proximal humeral fractures: Comparative agreement analysis and clinical implications 在严重肱骨近端骨折的Mitsuzawa分类中,计算机断层扫描与x线平片:比较一致分析和临床意义
Q2 Medicine Pub Date : 2025-11-20 DOI: 10.1016/j.jcot.2025.103276
Sadaki Mitsuzawa , Hisataka Takeuchi , Tadashi Yasuda , Shuichi Matsuda

Background

In a prior investigation, we demonstrated that the Mitsuzawa classification for dislocated and severely displaced proximal humeral fractures (PHFs) provided substantially higher reliability than the Neer or AO/OTA systems when applied to plain radiographs. The present study builds on that work by determining whether computed tomography (CT) alters classification outcomes or improves observer agreement.

Methods

Four independent reviewers—two shoulder specialists and two orthopedic residents—classified 70 PHFs according to the Neer, AO/OTA, and Mitsuzawa systems. Each fracture fulfilled criteria for dislocation or severe displacement requiring arthroplasty. Evaluations were performed at two separate timepoints: first with radiographs and then with CT scans, including three-dimensional reconstructions. Changes between modalities were recorded. Intraobserver consistency was assessed with the Cohen κ statistic, while interobserver reliability was evaluated with the Fleiss κ statistic.

Results

The incidence of axillary artery injury was 7.1 %. After CT review, classification changes occurred in 31 % of Neer, 29 % of AO/OTA, and 11 % of Mitsuzawa assessments. With radiographs alone, intraobserver reliability was moderate for Neer (κ = 0.52), substantial for AO/OTA (κ = 0.63), and substantial for Mitsuzawa (κ = 0.73). With CT imaging, the corresponding values were 0.55, 0.59, and 0.73. Interobserver agreement ranged from 0.43 to 0.45 (Neer), 0.49–0.52 (AO/OTA), and 0.68–0.68 (Mitsuzawa) with radiographs, and from 0.47 to 0.50, 0.57–0.57, and 0.67–0.69, respectively, after CT. Significant pairwise differences (p < 0.05) in interobserver agreement were observed among all combinations of the three systems for both modalities.

Conclusions

The Mitsuzawa classification was minimally influenced by imaging modality and consistently provided substantial agreement. For dislocated and displaced PHFs, CT appears to have only a minor influence on Mitsuzawa-based categorization, indicating that well-performed radiographs remain sufficient for reproducible classification. These findings have direct implications for clinical decision-making, imaging selection, and anticipating risks such as neurovascular compromise.
在之前的一项研究中,我们证明了Mitsuzawa对脱位和严重移位的肱骨近端骨折(phf)的分类在x线平片上比Neer或AO/OTA系统提供了更高的可靠性。本研究建立在该工作的基础上,通过确定计算机断层扫描(CT)是否改变了分类结果或提高了观察者的一致性。方法4名独立审审员(2名肩关节专家和2名骨科住院医师)根据Neer、AO/OTA和Mitsuzawa系统对70例phf进行分类。每个骨折都符合脱位或严重移位的标准,需要进行关节置换术。评估在两个不同的时间点进行:首先是x光片,然后是CT扫描,包括三维重建。记录不同模式之间的变化。采用Cohen κ统计量评估观察者内一致性,采用Fleiss κ统计量评估观察者间信度。结果腋窝动脉损伤发生率为7.1%。CT检查后,31%的never、29%的AO/OTA和11%的Mitsuzawa评估发生了分类改变。单独使用x线片时,观察者内信度对Neer为中等(κ = 0.52), AO/OTA为较大(κ = 0.63), Mitsuzawa为较大(κ = 0.73)。CT成像对应值分别为0.55、0.59、0.73。x线片的观察者间一致性为0.43 ~ 0.45 (Neer)、0.49 ~ 0.52 (AO/OTA)和0.68 ~ 0.68 (Mitsuzawa), CT后分别为0.47 ~ 0.50、0.57 ~ 0.57和0.67 ~ 0.69。在两种方式的三种系统的所有组合中,观察到观察者间一致性的显着两两差异(p < 0.05)。结论Mitsuzawa分型不受影像学方式的影响,且具有一致性。对于脱位和移位的phf, CT似乎对基于mitsuzawa的分类只有很小的影响,这表明表现良好的x线片仍然足以进行可重复的分类。这些发现对临床决策、影像学选择和预测神经血管损害等风险具有直接意义。
{"title":"Computed tomography versus plain radiography in the Mitsuzawa classification for severe proximal humeral fractures: Comparative agreement analysis and clinical implications","authors":"Sadaki Mitsuzawa ,&nbsp;Hisataka Takeuchi ,&nbsp;Tadashi Yasuda ,&nbsp;Shuichi Matsuda","doi":"10.1016/j.jcot.2025.103276","DOIUrl":"10.1016/j.jcot.2025.103276","url":null,"abstract":"<div><h3>Background</h3><div>In a prior investigation, we demonstrated that the Mitsuzawa classification for dislocated and severely displaced proximal humeral fractures (PHFs) provided substantially higher reliability than the Neer or AO/OTA systems when applied to plain radiographs. The present study builds on that work by determining whether computed tomography (CT) alters classification outcomes or improves observer agreement.</div></div><div><h3>Methods</h3><div>Four independent reviewers—two shoulder specialists and two orthopedic residents—classified 70 PHFs according to the Neer, AO/OTA, and Mitsuzawa systems. Each fracture fulfilled criteria for dislocation or severe displacement requiring arthroplasty. Evaluations were performed at two separate timepoints: first with radiographs and then with CT scans, including three-dimensional reconstructions. Changes between modalities were recorded. Intraobserver consistency was assessed with the Cohen κ statistic, while interobserver reliability was evaluated with the Fleiss κ statistic.</div></div><div><h3>Results</h3><div>The incidence of axillary artery injury was 7.1 %. After CT review, classification changes occurred in 31 % of Neer, 29 % of AO/OTA, and 11 % of Mitsuzawa assessments. With radiographs alone, intraobserver reliability was moderate for Neer (κ = 0.52), substantial for AO/OTA (κ = 0.63), and substantial for Mitsuzawa (κ = 0.73). With CT imaging, the corresponding values were 0.55, 0.59, and 0.73. Interobserver agreement ranged from 0.43 to 0.45 (Neer), 0.49–0.52 (AO/OTA), and 0.68–0.68 (Mitsuzawa) with radiographs, and from 0.47 to 0.50, 0.57–0.57, and 0.67–0.69, respectively, after CT. Significant pairwise differences (<em>p</em> &lt; 0.05) in interobserver agreement were observed among all combinations of the three systems for both modalities.</div></div><div><h3>Conclusions</h3><div>The Mitsuzawa classification was minimally influenced by imaging modality and consistently provided substantial agreement. For dislocated and displaced PHFs, CT appears to have only a minor influence on Mitsuzawa-based categorization, indicating that well-performed radiographs remain sufficient for reproducible classification. These findings have direct implications for clinical decision-making, imaging selection, and anticipating risks such as neurovascular compromise.</div></div>","PeriodicalId":53594,"journal":{"name":"Journal of Clinical Orthopaedics and Trauma","volume":"72 ","pages":"Article 103276"},"PeriodicalIF":0.0,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in sagittal spinopelvic parameters following S2-alar-iliac screw fixation in adult degenerative scoliosis: A one-year radiographic analysis of 80 patients 成人退行性脊柱侧凸骶髂螺钉固定后矢状椎盂参数的变化:80例患者一年的x线分析
Q2 Medicine Pub Date : 2025-11-20 DOI: 10.1016/j.jcot.2025.103278
Abhishek Soni , Vaibhav Sinha , Vidyadhara S , Balamurugan T

Background

S2-alar-iliac (S2AI) screws are widely used for spinopelvic fixation due to their biomechanical advantages. Although pelvic incidence (PI) is traditionally considered fixed after skeletal maturity, emerging evidence suggests that surgical procedures involving the sacroiliac joint may alter pelvic parameters. This study aimed to evaluate the effect of S2AI screw fixation on spinopelvic parameters and analyse variations based on preoperative PI values.

Methods

A retrospective review was conducted of 80 consecutive patients (160 screws) who underwent spinopelvic fusion for adult degenerative scoliosis between January 2020 and December 2023. Standing radiographs obtained preoperatively and at one-year follow-up were analysed for PI, pelvic tilt (PT), sacral slope (SS), and lumbar lordosis (LL). Patients were classified by preoperative PI as low (<40°), normal (40°–60°), or high (>60°). Changes >6° were considered clinically significant. Statistical analyses used paired t-tests and chi-squared tests (p < 0.05).

Results

PI significantly decreased from 50.45° ± 11.42°–46.18° ± 10.81° (p < 0.001), and PT decreased from 21.46° ± 10.45°–16.50° ± 9.19° (p < 0.001), while SS remained unchanged (p = 0.403). PI–LL mismatch improved from 18.26° ± 11.30°–8.07° ± 5.88° (p < 0.001). Clinically significant PI reduction (>6°) occurred in 40 % of patients, most frequently in those with high preoperative PI (64.7 % vs. 36.5 % normal, 18.2 % low; p = 0.043). ODI scores improved from 77.2 ± 12.1 to 33.9 ± 15.0 (p < 0.001), representing a 56 % reduction in disability, with all patients achieving the minimal clinically important difference. Hardware failure occurred in four screws (2.5 %) without related symptoms or need for revision, and alignment was maintained.

Conclusion

S2AI screw fixation significantly modifies spinopelvic parameters, challenging the concept of fixed PI after skeletal maturity. Greater PI reduction in patients with high preoperative PI highlights its relevance for surgical planning in adult spinal deformity correction.
S2AI螺钉由于其生物力学优势被广泛应用于脊柱-骨盆固定。尽管传统上认为骨盆发生率(PI)在骨骼成熟后是固定的,但新出现的证据表明,涉及骶髂关节的外科手术可能会改变骨盆参数。本研究旨在评估S2AI螺钉固定对脊柱骨盆参数的影响,并分析术前PI值的变化。方法回顾性分析2020年1月至2023年12月期间连续80例(160枚螺钉)行脊柱盆腔融合术治疗成人退行性脊柱侧凸的患者。术前和随访一年的站立x线片分析PI、骨盆倾斜(PT)、骶骨倾斜(SS)和腰椎前凸(LL)。患者根据术前PI分为低(40°)、正常(40°-60°)和高(60°)。变化>;6°被认为具有临床意义。统计分析采用配对t检验和卡方检验(p < 0.05)。结果spi从50.45°±11.42°降至46.18°±10.81°(p < 0.001), PT从21.46°±10.45°降至16.50°±9.19°(p < 0.001), SS保持不变(p = 0.403)。PI-LL不匹配改进从18.26°±11.30°-8.07°±5.88°(p & lt; 0.001)。临床上明显的PI降低(>6°)发生在40%的患者中,最常见于术前PI高的患者(64.7%比36.5%正常,18.2%低;p = 0.043)。ODI评分从77.2±12.1提高到33.9±15.0 (p < 0.001),代表残疾减少56%,所有患者均达到最小的临床重要差异。4颗螺钉(2.5%)发生硬件故障,无相关症状或需要翻修,并保持对准。结论s2ai螺钉固定明显改变了脊柱骨盆参数,挑战了骨骼成熟后固定PI的概念。术前PI高的患者更大的PI降低强调了其与成人脊柱畸形矫正手术计划的相关性。
{"title":"Changes in sagittal spinopelvic parameters following S2-alar-iliac screw fixation in adult degenerative scoliosis: A one-year radiographic analysis of 80 patients","authors":"Abhishek Soni ,&nbsp;Vaibhav Sinha ,&nbsp;Vidyadhara S ,&nbsp;Balamurugan T","doi":"10.1016/j.jcot.2025.103278","DOIUrl":"10.1016/j.jcot.2025.103278","url":null,"abstract":"<div><h3>Background</h3><div>S2-alar-iliac (S2AI) screws are widely used for spinopelvic fixation due to their biomechanical advantages. Although pelvic incidence (PI) is traditionally considered fixed after skeletal maturity, emerging evidence suggests that surgical procedures involving the sacroiliac joint may alter pelvic parameters. This study aimed to evaluate the effect of S2AI screw fixation on spinopelvic parameters and analyse variations based on preoperative PI values.</div></div><div><h3>Methods</h3><div>A retrospective review was conducted of 80 consecutive patients (160 screws) who underwent spinopelvic fusion for adult degenerative scoliosis between January 2020 and December 2023. Standing radiographs obtained preoperatively and at one-year follow-up were analysed for PI, pelvic tilt (PT), sacral slope (SS), and lumbar lordosis (LL). Patients were classified by preoperative PI as low (&lt;40°), normal (40°–60°), or high (&gt;60°). Changes &gt;6° were considered clinically significant. Statistical analyses used paired t-tests and chi-squared tests (p &lt; 0.05).</div></div><div><h3>Results</h3><div>PI significantly decreased from 50.45° ± 11.42°–46.18° ± 10.81° (p &lt; 0.001), and PT decreased from 21.46° ± 10.45°–16.50° ± 9.19° (p &lt; 0.001), while SS remained unchanged (p = 0.403). PI–LL mismatch improved from 18.26° ± 11.30°–8.07° ± 5.88° (p &lt; 0.001). Clinically significant PI reduction (&gt;6°) occurred in 40 % of patients, most frequently in those with high preoperative PI (64.7 % vs. 36.5 % normal, 18.2 % low; p = 0.043). ODI scores improved from 77.2 ± 12.1 to 33.9 ± 15.0 (p &lt; 0.001), representing a 56 % reduction in disability, with all patients achieving the minimal clinically important difference. Hardware failure occurred in four screws (2.5 %) without related symptoms or need for revision, and alignment was maintained.</div></div><div><h3>Conclusion</h3><div>S2AI screw fixation significantly modifies spinopelvic parameters, challenging the concept of fixed PI after skeletal maturity. Greater PI reduction in patients with high preoperative PI highlights its relevance for surgical planning in adult spinal deformity correction.</div></div>","PeriodicalId":53594,"journal":{"name":"Journal of Clinical Orthopaedics and Trauma","volume":"72 ","pages":"Article 103278"},"PeriodicalIF":0.0,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Clinical Orthopaedics and Trauma
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