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Trends in Stereotactic Radiosurgery for Meningioma: the Top 100 Most Cited Articles. 脑膜瘤立体定向放射外科的发展趋势:被引用次数最多的 100 篇文章。
Q3 Medicine Pub Date : 2024-01-01
Tariq Al Habsi, Hashim Alibrahim, Utba Al Manthari, Adham Al-Rahbi, Tariq Al-Saadi

Background: Stereotactic radiosurgery is a well-known and influential management option for meningioma. This article aims to highlight the most cited publications on this topic.

Methods: All Scopus articles published in English under Stereotactic radiosurgery and meningioma were sorted according to the number of citations. The keywords used were: "Stereotactic radiosurgery, SRS, Meningioma, Intracranial meningioma". The top 100 cited articles meeting the criteria were included. Certain features of these articles were collected and analyzed using Microsoft Excel and SPSS.

Results: The included articles were published between 1991 and 2020 with a total of 9149 citations. The most cited article is "Meningiomas: Knowledge base, treatment outcomes, and uncertainties. A RANO review" by Rogers L. et al. 2015 with 349 citations. No significant association was found between the number of citations and the impact factor of the publishing journal.

Conclusion: This study gives a concise and updated summary of impactful research on stereotactic radiosurgery and meningioma, highlighting the main contributors and scientific connections.

背景:立体定向放射外科手术是脑膜瘤的一种著名且有影响力的治疗方案。本文旨在重点介绍有关这一主题的被引用次数最多的出版物:根据引用次数对立体定向放射外科和脑膜瘤项下所有 Scopus 英文发表文章进行排序。使用的关键词为"立体定向放射外科、SRS、脑膜瘤、颅内脑膜瘤"。符合标准的前 100 篇被引文章被收录其中。使用 Microsoft Excel 和 SPSS 收集并分析了这些文章的某些特征:结果:纳入的文章发表于 1991 年至 2020 年之间,总引用次数为 9149 次。被引用次数最多的文章是 "脑膜瘤:知识基础、治疗结果和不确定性。罗杰斯-L.等人2015年发表的 "A RANO综述",共被引用349次。引用次数与发表期刊的影响因子之间未发现明显关联:本研究对立体定向放射外科和脑膜瘤方面有影响的研究进行了简明扼要的最新总结,突出了主要贡献者和科学联系。
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引用次数: 0
Clear Cell Meningioma with Tyrosine Crystals: a Case Report with Review of Literature. 带有酪氨酸晶体的透明细胞脑膜瘤:病例报告与文献综述。
Q3 Medicine Pub Date : 2024-01-01
Rashim Sharma, Poonam Abhay Elhence, Deepak Vedant, Jigish Ruparelia, Suryanarayanan Bhaskar, Sarbesh Tiwari

Introduction or background: Clear cell meningioma is a rare WHO grade 2 tumour and runs an aggressive course. Tyrosine crystals are very uncommon in meningioma.

Case presentation: We present a case of a 43-year female with right middle and posterior cranial fossa space occupying lesion (SOL) diagnosed as clear cell meningioma with presence of numerous tyrosine crystals.

Discussion and conclusion: Whether these crystals are incidentally noted or if there is an actual relationship of these crystals with tumour environment must be found as they are seen in many other conditions too.

导言或背景:透明细胞脑膜瘤是一种罕见的WHO 2级肿瘤,病程凶险。酪氨酸晶体在脑膜瘤中非常罕见:病例介绍:我们介绍了一例 43 岁女性右侧中后颅窝占位性病变(SOL),诊断为透明细胞脑膜瘤,并伴有大量酪氨酸晶体:这些晶体是偶然发现的,还是与肿瘤环境有实际关系,必须加以研究,因为它们也见于许多其他疾病。
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引用次数: 0
URS-SM procedure using Pneumatic lithotriptor for the management of ureteral stones-our experience. 使用气动碎石机治疗输尿管结石的 URS-SM 程序--我们的经验。
Q3 Medicine Pub Date : 2024-01-01
Xh Çuni, S Mehmeti, A Neziri, L Çuni, D Mucaj, D Çuni

Introduction: We assessed the effectiveness of URS-SM procedure for ureteral stones located in different parts of ureter and to determine outcomes in terms of success rate, complications, and operation time.

Methods: After obtaining approval of the Institutional Clinical Board of urology, we reviewed data of consecutive 102 patients treated at our Urology Department with URSSM procedure in cohort study January 2023-May 2023.

Results: There were 44 (43,2%) men and 58 (56,8%) women with a mean age of 43.7 (range 7-78) years old. Most patients had stone on left side 46 ptts (52%), 39 ptts. on right side (38,2%) and on both sides in 10 ptts. (9.8%). The overall success rate after session of URSSMs was 87,3%. Postoperative complications we had only in one case, urosepsis in a diabetic old man (75 years). Operation time was 36 (± 13) min.

Conclusions: The URS-SM procedure is an effective treatment with a low rate of complications. Keyword: URS-SM, ureter stones, pneumatic device.

引言我们评估了URS-SM手术治疗位于输尿管不同部位的输尿管结石的效果,并确定了成功率、并发症和手术时间方面的结果:在获得泌尿外科临床委员会的批准后,我们回顾了 2023 年 1 月至 2023 年 5 月在我院泌尿外科接受 URSSM 手术治疗的连续 102 例患者的数据:其中男性 44 人(43.2%),女性 58 人(56.8%),平均年龄 43.7 岁(7-78 岁不等)。大多数患者的结石位于左侧 46 人(52%),右侧 39 人(38.2%),两侧均有 10 人(9.8%)。(9.8%).URSSM手术后的总成功率为87.3%。术后并发症只有一例,是一名糖尿病老人(75 岁)的尿道炎。手术时间为 36 (± 13) 分钟:URS-SM手术是一种有效的治疗方法,并发症发生率较低。关键词:URS-SM、输尿管结石、气动装置。
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引用次数: 0
Scrotal Wall Metastasis from Adenocarcinoma of Unknown Origin, with Concurrent Extramammary Paget's Disease - a Case Report. 来源不明的腺癌的阴囊壁转移,并发乳腺外Paget病一例报告。
Q3 Medicine Pub Date : 2023-09-01
Liang Meng Loy, Kiat Yee Elise Vong, Szu Lyn Cristine Ding, Zhan Peng Daniel Yong, Justin Kwan, Bien Peng Tan

Introduction: Scrotal cancer is a very rare disease, with the most common subtype being squamous cell carcinoma. Metastatic carcinoma to the scrotal wall is very rare. A histological finding of adenocarcinoma in a scrotal malignancy invariably suggests a metastasis from another primary cancer. We describe an enigmatic case of metastatic adenocarcinoma to the scrotum managed as metastatic adenocarcinoma of unknown origin. Attempts to identify a primary cancer were complicated by ambiguous diagnostic results. This is the first case in literature of metastatic cancer to the scrotum from an adenocarcinoma of unknown origin, and this was complicated by concurrent extramammary Paget's disease.

Case presentation: A 70-year-old male presented with painless progressive scrotal skin swelling, which was shown on histology to be adenocarcinoma. Immunohistochemistry showed prostatic lineage markers. However, the argument for a prostatic primary was weakened by negative prostate transrectal ultrasound biopsy findings and negative radiological findings. The scrotal metastatic adenocarcinoma was managed as metastatic adenocarcinoma of unknown origin. A differential of occult poorly differentiated prostatic primary was considered in view of the clinical phenotype of an elderly male patient with extensive sclerotic bony metastases, immunohistochemistry results and relatively low PSA level in relation to systemic burden of disease. The patient was managed with palliative systemic chemotherapy (carboplatin/paclitaxel) with initial disease response, but eventually developed progressive disease.

Discussion and conclusion: Finding of adenocarcinoma in scrotal skin malignancy indicates a metastasis and should prompt further work-up to identify a primary cancer, particularly of other genitourinary or lower gastrointestinal origin, so that treatment can be targeted at the underlying primary malignancy. However, attempts to identify a primary cancer might be complicated by ambiguous diagnostic results.

简介:睾丸癌症是一种非常罕见的疾病,最常见的亚型是鳞状细胞癌。阴囊壁转移癌是非常罕见的。阴囊恶性肿瘤中腺癌的组织学发现总是提示来自另一原发性癌症的转移。我们描述了一个神秘的阴囊转移腺癌病例,作为不明来源的转移腺癌处理。鉴别原发性癌症的尝试因不明确的诊断结果而变得复杂。这是文献中第一例不明原因的腺癌转移到阴囊的癌症,并伴有乳腺外Paget病。病例介绍:一名70岁男性,出现无痛性进行性阴囊皮肤肿胀,组织学显示为腺癌。免疫组织化学显示前列腺谱系标记。然而,前列腺经直肠超声活检阴性结果和放射学阴性结果削弱了原发性前列腺的论点。阴囊转移性腺癌被视为来源不明的转移腺癌。考虑到一名患有广泛硬化性骨转移的老年男性患者的临床表型、免疫组织化学结果以及与系统疾病负担相关的相对较低的PSA水平,考虑了隐匿性低分化原发性前列腺的差异。患者接受了姑息性全身化疗(卡铂/紫杉醇),最初有疾病反应,但最终发展为进行性疾病。讨论和结论:阴囊皮肤恶性肿瘤中发现腺癌表明有转移,应促使进一步检查以确定原发性癌症,特别是其他泌尿生殖系统或下消化道来源的癌症,以便针对潜在的原发性恶性肿瘤进行治疗。然而,识别原发性癌症的尝试可能会因诊断结果不明确而变得复杂。
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引用次数: 0
Outcomes of Breast Intraoperative Electron Beam Radiotherapy (IOeRT) : Case Series of Single Institute Experience in Saudi Arabia. 乳腺术中电子束放射治疗(IOeRT)的结果:沙特阿拉伯单一研究所经验的病例系列。
Q3 Medicine Pub Date : 2023-09-01
Abdullah Alsuhaibani, Abdul Rahman Alqahtani, Abdulaziz Alsaif, Areej Bokhari, Basel AlMefleh, Yara Aldigi, Tareq Salah

Introduction: 85-90% of local recurrences after breastconserving surgery occurs within the index quadrant. Intraoperative radiotherapy may be a good alternative for eligible patients avoiding long course of adjuvant radiation.

Patients and methods: Eligible patients were early stage node negative at least 50 years at time of inclusion, unicentric less than 30mm in diameter any hormone receptor status. 21 Gy was delivered intraoperatively, biologically equivalent to 58 to 60 Gy in standard fractionation using electron beam to 90% isodose line. Cosmetic, Oncological and Patient Satisfaction Evaluation of treated Patients between March 2018 and August 2020 at the King Khalid university hospital, using the IOeRT (Mobetron® ). Evaluation done at a combined clinic between surgical and radiation oncology teams at the end of the follow up period before publication.

Results: 15 female patients were evaluable with mean follow up period 33.8 months (19-48 months). Mean Age 56.4 years (50-65 years). Mean tumor size 1.213 cm. Majority of patients were T1. 2 patients showed Sentinel lymph node positive.21 Gy was delivered intraoperatively.4 Patients (26.7%) received adjuvant postoperative external beam radiation therapy (EBRT). 2 patients due to being in Caution group due to positive extensive Ductal carcinoma in situ (DCIS). External beam radiation was 40 Gy/15 fractions/3 weeks using three dimensional radiation therapy (3DCRT). Cosmetically, Apart from one patient score 9 due to presence of keloid scar formation, most patients were in range of 0-3 according to physician evaluation and Modified Hollander's score otherwise, No more than score 3 in any of the patients was detected. Oncologically, Till the time of publication no local or distant relapses was detected. As a patient experience, 100 % of patients were satisfied.

Conclusion: Breast IOERT is a convenient, safe and a valid treatment modality as an option for patients who are otherwise appropriate candidates for APBI. Proper patient selection should focus on clinicopathologic factors predictive of negative nodes and negative margins. Careful assessment of preoperative mammographic and other imaging studies for features, such as extent of calcifications, may be helpful.

引言:保乳手术后85-90%的局部复发发生在指数象限内。对于符合条件的患者来说,术中放疗可能是一个很好的替代方案,可以避免长期的辅助放疗。患者和方法:符合条件的患者在纳入时为早期淋巴结阴性,至少50年,单核直径小于30mm,任何激素受体状态。术中给予21Gy,在生物学上相当于使用电子束到90%等剂量线的标准分级中的58-60Gy。2018年3月至2020年8月在哈立德国王大学医院使用IOeRT(Mobetron®)对接受治疗的患者进行美容、肿瘤学和患者满意度评估。在发表前的随访期结束时,在外科和放射肿瘤学团队的联合诊所进行评估。结果:15例女性患者的平均随访期为33.8个月(19-48个月)。平均年龄56.4岁(50-65岁)。平均肿瘤大小1.213cm。大多数患者为T1。哨兵淋巴结阳性2例,术中给予21Gy。4例(26.7%)接受术后辅助外束放射治疗(EBRT)。2例患者因广泛性原位导管癌(DCIS)阳性而被归入Caution组。使用三维放射治疗(3DCRT)的外束辐射为40Gy/15次/3周。美容方面,除了一名患者因瘢痕疙瘩形成而得分为9外,根据医生的评估和改良Hollander评分,大多数患者的得分在0-3之间,任何患者的得分都不超过3。在肿瘤学上,截至发表之时,未发现局部或远处复发。作为患者体验,100%的患者感到满意。结论:乳腺IOERT是一种方便、安全和有效的治疗方式,可作为APBI患者的一种选择。适当的患者选择应侧重于预测阴性淋巴结和阴性边缘的临床病理因素。仔细评估术前乳房X光检查和其他影像学研究的特征,如钙化程度,可能会有所帮助。
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引用次数: 0
Outcomes of Vacuum-Assisted Beast Biopsy for Management of Benign Breast Masses. 良性乳腺肿块的真空辅助Beast活检结果。
Q3 Medicine Pub Date : 2023-09-01
Khalil Terro, Khalid ALhajri, Mariam ALshammari

Introduction: The triple assessment, which combines a clinical examination, radiological imaging, and pathology, is used to assess the breast mass. The open excision of the suspicious lesion is the gold standard for breast biopsy techniques. However, because an excisional biopsy always results in a scar, many surgeons are considering less invasive, alternative methods due to the cost and morbidity of this operation. Image-guided percutaneous core-needle biopsy has recently gained popularity in identifying palpable and non-palpable breast lesions. Vacuum- assisted breast biopsy (VABB) was created to address some of these limitations of core-needle biopsy.

Methodology: We performed a retrospective review of 38 patients who underwent VABB.To Report the recurrence one-year post-VABB for management of benign breast masses and To evaluate patient-reported cosmetic satisfaction using the cosmetic scale.

Results: The mean age of the study participants was about 30.34 (±10.11) years. The average size of breast masses was 1.23 (±0.83) cm. The recurrence rate was 13.16%, confirmed by follow up ultrasound and all these patients underwent excisional biopsy. There were significant differences in breast mass recurrence rate by the side affected. Recurrence was more likely in right-sided breast masses (P=0.048).In our study, no significant relationships between the occurrence of complications following surgery and patients 'demographics and mass features and no infection were reported. The hematoma was reported in 2 patients 5.26 %, Mild induration at the site of surgery 2 patients 5.26 %, Small contusion at the site of surgery in one patient 2.63 % and no other complication was reported. The patient's cosmetic satisfaction using the cosmetic scale from 1-5,1: not satisfied,2:low satisfaction,3:mild satisfaction,4:moderate satisfaction,5; completely satisfied, The mean cosmetic score was 4.03.

Conclusion: Our study concluded that VABB is reliable for removing small benign breast masses with a satisfying cosmetic outcome &low recurrence rate, and fewer complications.

引言:三重评估结合了临床检查、放射学成像和病理学,用于评估乳腺肿块。可疑病变的开放切除是乳腺活检技术的黄金标准。然而,由于切除活组织检查总是会导致疤痕,由于这种手术的成本和发病率,许多外科医生正在考虑微创的替代方法。图像引导的经皮核心针活检术最近在识别可触摸和不可触摸的乳腺病变方面越来越受欢迎。真空辅助乳腺活检(VABB)是为了解决核心针活检的一些局限性而创建的。方法:我们对38例接受VABB的患者进行了回顾性审查。报告VABB后一年良性乳腺肿块的复发情况,并使用美容量表评估患者报告的美容满意度。结果:研究参与者的平均年龄约为30.34(±10.11)岁。乳腺肿块的平均大小为1.23(±0.83)cm。随访超声证实,复发率为13.16%,所有患者均接受了切除活检。受影响侧乳腺肿块复发率存在显著差异。右侧乳腺肿块复发的可能性更大(P=0.048)。在我们的研究中,手术后并发症的发生与患者的人口统计学和肿块特征之间没有显著关系,也没有感染报告。血肿2例5.26%,手术部位轻度硬结2例5.26%,手术部位小挫伤1例2.63%,无其他并发症报告。患者使用美容量表的美容满意度为1-5,1:不满意,2:低满意度,3:轻度满意度,4:中度满意度,5;完全满意,平均美容评分为4.03。结论:我们的研究得出结论,VABB是去除小型良性乳腺肿块的可靠方法,美容效果令人满意,复发率低,并发症少。
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引用次数: 0
Early Development of Cancer Treatments. 癌症治疗的早期发展。
Q3 Medicine Pub Date : 2023-09-01
Zainab H Almansour

The treatment of cancer has evolved as our understanding of the underlying biological processes has improved. Yet, the efficient delivery of cancer therapeutics remains a major challenge in the filed necessitating a multidisciplinary approach that integrates knowledge obtained from diverse fields, such as chemistry, biology, engineering, and medicine. Cancer treatment aims to remove all or most of the tumor as possible and to prevent the recurrence or spread of the primary tumor. Cancer treatment involves a careful examination of the available options, which may include a combination of the major treatment methods, such as surgery with chemotherapy and/or radiation therapy. The type of therapy chosen depends on several factors, such as the location, grade, and stage of the tumor, as well as the patient's performance status. As new knowledge about cancer biology becomes available, treatments will be developed and modified in the pursuit of cancer cures to improve efficacy, precision, survivability, and quality of life. The main objective of this review is to expand our understanding of the early development of commonly applied cancer treatment strategies: surgery, chemotherapy, and radiotherapy. Keywords: Chemotherapy; Radiotherapy; Surgery; Therapy; Tumor.

癌症的治疗随着我们对潜在生物学过程的理解的提高而发展。然而,癌症疗法的有效提供仍然是该领域的一个主要挑战,需要采用多学科方法,整合从化学、生物学、工程和医学等不同领域获得的知识。癌症治疗旨在尽可能切除全部或大部分肿瘤,并防止原发肿瘤的复发或扩散。癌症治疗包括仔细检查可用的选择,其中可能包括主要治疗方法的组合,如手术与化疗和/或放射治疗。选择的治疗类型取决于几个因素,如肿瘤的位置、级别和分期,以及患者的表现状态。随着癌症生物学的新知识变得可用,在追求癌症治疗的过程中,将开发和修改治疗方法,以提高疗效、准确性、生存能力和生活质量。这篇综述的主要目的是扩大我们对常用癌症治疗策略的早期发展的理解:手术、化疗和放疗。关键词:化疗;放射治疗;外科手术治疗肿瘤。
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引用次数: 0
Comparison of Effectiveness of Moringa Oleifera Leaves Extract Gel (2%) with Retino A (0.1%) Cream for Treatment of Oral Leukoplakia: Double Blinded Randomized Control Trial. 辣木叶提取物凝胶(2%)与维A(0.1%)乳膏治疗口腔白斑的疗效比较:双盲随机对照试验。
Q3 Medicine Pub Date : 2023-09-01
Sulem Ansari, Shivayogi Charantimath, Anabelle Fernandes, Jayraj B Malik, Prashanth Panta

Aim: The study aims to evaluate and compare the efficacy of Moringa oleifera leaf extract gel (2%) & Retino A cream (0.1%) in reducing the size of lesions in oral leukoplakia.

Objectives: The present study aimed to evaluate the efficacy of two interventions, Moringa oleifera mucoadhesive gel and Retino-A cream, in reducing the size of lesions in patients with oral leukoplakia. Specifically, the objectives were: (1) to assess the efficacy of Moringa oleifera mucoadhesive gel in determining the reduction in lesion size, (2) to assess the efficacy of Retino-A cream in determining the reduction in lesion size, and (3) to compare the efficacy of Moringa oleifera mucoadhesive gel (2%) in determining the change in lesion size in oral leukoplakia patients.

Methods: Clinically diagnosed cases of oral Leukoplakia were included in this study. The sample size is 72. Thirty-six patients had lesion sizes ranging from 2- 4 cm, and 36 patients had lesion sizes ranging from 4.1 - 6 cm that were equally distributed in the case and control groups using the chit system. The case and control groups had 36 patients with an equal size range of lesions. The case and control group participants will be advised topical application of the intervention and Retino-A thrice daily using a sterile cotton bud.

Results: M. oleifera gel (2%) was found to be more effective in the reduction in the size of the lesion as compared to Retino-A in the treatment of oral leukoplakia patients.

Conclusion: This study showed that M. oleifera mucoadhesive gel (2%) is an effective and safe treatment option for oral leukoplakia patients. It demonstrated a significant reduction in lesion size compared to Retino-A cream (0.1%) after 3 months of therapy, without any reported adverse effects. However, long-term follow-up studies are needed to evaluate its long-term effectiveness. The potent antioxidant property of M. oleifera makes it a promising candidate for further studies with concentration variations and in other potentially malignant oral disorders, such as lichen planus and OSMF. The development of chemotherapeutic drugs from M. oleifera for cancer treatment should also be considered. Overall, M. oleifera appears to be a promising natural alternative to synthetic drugs for the treatment of oral leukoplakia.

Key words: Leukoplakia, Oral leukoplakia, premalignant lesion, precancer, potentially malignant disorders.

目的:本研究旨在评估和比较辣木叶提取物凝胶(2%)和维甲酸乳膏(0.1%)在缩小口腔白斑病变面积方面的疗效。目的:本研究旨在评估两种干预措施,辣木粘膜粘附凝胶和视黄醇-A乳膏,在缩小口腔白斑患者病变面积方面的疗效。具体而言,目的是:(1)评估辣木粘膜粘附凝胶在确定病变大小缩小方面的疗效,(2)评估视黄醇-A乳膏在确定病变尺寸缩小方面的功效,以及(3)比较辣木粘膜粘合凝胶(2%)在确定口腔白斑患者病变大小变化方面的疗效。方法:将临床诊断为口腔白斑的病例纳入本研究。样本量为72。36名患者的病变大小在2-4厘米之间,36名患者病变大小在4.1-6厘米之间,在使用chit系统的病例组和对照组中分布均匀。病例组和对照组有36名患者,病变范围相等。将建议病例组和对照组参与者使用无菌棉芽每天三次局部应用干预和视黄醇-A。结果:在治疗口腔白斑患者时,发现橄榄油凝胶(2%)在缩小病变大小方面比Retino-A更有效。结论:本研究表明,2%的油桐粘膜粘附凝胶是治疗口腔白斑有效、安全的选择。治疗3个月后,与Retino-a乳膏(0.1%)相比,其病变面积显著缩小,没有任何不良反应报告。然而,需要进行长期的后续研究来评估其长期有效性。油的强大抗氧化特性使其成为进一步研究浓度变化和其他潜在恶性口腔疾病(如扁平苔藓和OSMF)的有希望的候选者。还应考虑从油中开发用于治疗癌症的化疗药物。总的来说,橄榄油似乎是治疗口腔白斑的一种很有前途的天然替代合成药物。关键词:白斑,口腔白斑,癌前病变,癌前疾病,潜在恶性疾病。
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引用次数: 0
Barriers related to Oral Cancer Screening, Diagnosis and Treatment in Karnataka, India. 印度卡纳塔克邦与口腔癌症筛查、诊断和治疗相关的障碍。
Q3 Medicine Pub Date : 2023-09-01
Vijay C R, Ramesh C, P Sridhar, C Ramachandra, Madhu Kumar

Background: The most predominant cancer in India is Oral cancer. Annually 130,000 people yield to oral cancer in India, which translates into about 14 deaths per hour and 60-80% of patients present with advanced disease as compared to 40% in developed countries.

Aim: To decide factors associated with primary, secondary and tertiary delays and identify reasons for a lack of follow-up.

Materials and methods: This study was conducted at the Kidwai Memorial Institute of Oncology, Bengaluru. A hospitalbased cross-sectional study using the direct personal interview method was done. A total of 200 oral cancer patients were included in the study.

Results: 34.5% were men and 65.5% were women. About 97.5% of patients were engaged with either one of the habits like smoking, chewing or alcohol consumption. 84% of patients were not aware of the risk of getting oral cancer. 29% of people agreed that tobacco and alcohol are risk factors for oral cancer and they know about the signs of oral cancer. If detected early, cure rates were higher compared to illiterate people and this difference is statistically significant p< 0.05. 83.5% of patients did not know that oral cancer can be diagnosed early by regular screening of the oral cavity. The cost of staying near a Regional cancer centre, job security, and the social and economic burden on relatives were significant barriers to incomplete treatment and a decreased follow-up rate.

Conclusion: Low awareness is the main barrier to oral cancer detection. Conducting cancer awareness and screening camps frequently will detect oral cancers at an early stage.

Key words: Oral Cancer, Barriers, Cancer awareness, Oral Screening.

背景:印度最主要的癌症是口腔癌症。在印度,每年有13万人患口腔癌症,这意味着每小时约有14人死亡,60-80%的患者患有晚期疾病,而发达国家的这一比例为40%。目的:确定与原发性、继发性和三次延误相关的因素,并确定缺乏随访的原因。材料和方法:本研究在班加罗尔Kidwai纪念肿瘤研究所进行。采用直接个人访谈法进行了一项基于医院的横断面研究。共有200名口腔癌症患者被纳入研究。结果:男性34.5%,女性65.5%。约97.5%的患者有吸烟、咀嚼或饮酒等习惯。84%的患者没有意识到患口腔癌症的风险。29%的人认为烟草和酒精是口腔癌症的危险因素,他们知道口腔癌症的迹象。如果早期发现,治愈率高于文盲,这一差异具有统计学意义,p<0.05。83.5%的患者不知道通过定期口腔筛查可以早期诊断口腔癌症。住在癌症区域中心附近的费用、工作保障以及亲属的社会和经济负担是不完全治疗和随访率下降的重大障碍。结论:低认知是口腔癌症检测的主要障碍。经常举办癌症宣传和筛查营将在早期发现口腔癌。关键词:口腔癌症,障碍,癌症意识,口腔筛查。
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引用次数: 0
Glioblastoma with Primitive Neuroectodermal Tumor like Component: Rare and Enigmatic. 具有原始神经外胚层肿瘤样成分的胶质母细胞瘤:罕见且神秘。
Q3 Medicine Pub Date : 2023-09-01
Sameer Ahmed Ansari, Mahera Roohi, Khalifa A Al Doseri, Khalid Ahmed Alsindi, Talal A Almayman

Glioblastoma (GBM) with Primitive Neuroectodermal tumor (PNET) like features is an extremely rare tumor showing dual features of malignant glioma and primitive neuroectodermal tumour occurring mostly in adults. It poses diagnostics dilemma to the neuropathologist and treating oncologist team because of its rarity, tendency to spread to cerebrospinal fluid and dismal prognosis. We have described this tumor in a 11 years old male child in this case report. Keywords: glioma,glioblastoma,primitive neuroectodermal tumor, variant, pediatric.

具有原始神经外胚层肿瘤(PNET)样特征的胶质母细胞瘤(GBM)是一种极为罕见的肿瘤,具有恶性胶质瘤和原始神经外胚层肿瘤的双重特征,主要发生在成人中。由于其罕见、易于扩散到脑脊液以及预后不佳,它给神经病理学家和肿瘤治疗团队带来了诊断难题。我们在本病例报告中描述了一名11岁男性儿童的肿瘤。关键词:神经胶质瘤,胶质母细胞瘤,原始神经外胚层肿瘤,变异,儿科。
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The gulf journal of oncology
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