Pub Date : 2025-12-12DOI: 10.1021/acs.nanolett.5c05189
Shujing Wang,Lei Rong,Wenxuan He,Yau Kei Chan,Shuangquan Lai,Yi Deng
The growing demand for high-security optical encryption and anticounterfeiting technologies necessitates the development of full-spectrum multimodal luminescence materials and strategies. However, integrating full-color emission and multilevel response modes within a single system remains challenging. Herein, a facile one-pot solvothermal strategy is developed to tailor two distinct carbon dots (CDs), dispersed CDs (d-CDs) and aggregated CDs (a-CDs), exhibiting full-spectrum multimodal photoluminescence. Systematic investigations reveal that the multicolor emission originates from intrinsic, deep defective, and surface states in both d-CDs and a-CDs, while a-CDs uniquely exhibit an additional molecular state via intramolecular charge transfer. Remarkably, the photoluminescence behavior can be dynamically modulated by solvent polarity and hydrogen bonding, enabling on-demand full-spectrum photoluminescence responses. With the leverage of these exceptional full-spectrum solvatofluorochromic properties, advanced encryption platforms with high-level security are demonstrated. This work not only deciphers the multicolor emission origins and solvatofluorochromic mechanisms of CDs but also offers new perspectives for designing intelligent materials for optical security applications.
{"title":"Tailoring Full-Spectrum Solvatofluorochromic Carbon Dots: Deciphering Tunable Multicolor Emission Mechanisms toward Advanced Photonic Cryptography.","authors":"Shujing Wang,Lei Rong,Wenxuan He,Yau Kei Chan,Shuangquan Lai,Yi Deng","doi":"10.1021/acs.nanolett.5c05189","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c05189","url":null,"abstract":"The growing demand for high-security optical encryption and anticounterfeiting technologies necessitates the development of full-spectrum multimodal luminescence materials and strategies. However, integrating full-color emission and multilevel response modes within a single system remains challenging. Herein, a facile one-pot solvothermal strategy is developed to tailor two distinct carbon dots (CDs), dispersed CDs (d-CDs) and aggregated CDs (a-CDs), exhibiting full-spectrum multimodal photoluminescence. Systematic investigations reveal that the multicolor emission originates from intrinsic, deep defective, and surface states in both d-CDs and a-CDs, while a-CDs uniquely exhibit an additional molecular state via intramolecular charge transfer. Remarkably, the photoluminescence behavior can be dynamically modulated by solvent polarity and hydrogen bonding, enabling on-demand full-spectrum photoluminescence responses. With the leverage of these exceptional full-spectrum solvatofluorochromic properties, advanced encryption platforms with high-level security are demonstrated. This work not only deciphers the multicolor emission origins and solvatofluorochromic mechanisms of CDs but also offers new perspectives for designing intelligent materials for optical security applications.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"29 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145732642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-12DOI: 10.1021/acs.nanolett.5c04285
Quanxing Zhai, Bo Zhu, Wenqi Gong, Yue Hou, Runyan Gu, Tangyang Pu, Cheng Lei, Sheng Liu, Ziyu Wang, Du Wang
Dense dislocations effectively reduce the thermal conductivity, thereby enhancing the zT of thermoelectric materials. However, the general down-top strategy involves doping screened elements and synthetic processing, thereby reducing its universality. In this paper, laser shock dislocation proliferation (LSDP) is utilized to construct ∼1013/cm2 dislocations into Ag2Se material, which is 2–3 orders higher than spark plasma sintering (SPS) samples. Theoretical analysis demonstrates that the peak pressure exceeds 4.5 GPa, while the effective pressure duration reaches 198 ns, with the impact depth exceeding 0.5 mm and the strain rate reaching 1.52 × 107 s–1. The introduction of dense dislocations via laser shock reduced the total thermal conductivity by 23.2% and the lattice thermal conductivity by 17.1%. Using a double-sided shock strategy achieved a zT of 0.91, a 40% increase over the SPS samples. This work demonstrates the effectiveness of LSDP in constructing dense dislocations in brittle thermoelectric materials.
{"title":"Laser Shock Dislocation Proliferation Drives Enhanced Thermoelectric Performance in Ag2Se","authors":"Quanxing Zhai, Bo Zhu, Wenqi Gong, Yue Hou, Runyan Gu, Tangyang Pu, Cheng Lei, Sheng Liu, Ziyu Wang, Du Wang","doi":"10.1021/acs.nanolett.5c04285","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c04285","url":null,"abstract":"Dense dislocations effectively reduce the thermal conductivity, thereby enhancing the <i>zT</i> of thermoelectric materials. However, the general down-top strategy involves doping screened elements and synthetic processing, thereby reducing its universality. In this paper, laser shock dislocation proliferation (LSDP) is utilized to construct ∼10<sup>13</sup>/cm<sup>2</sup> dislocations into Ag<sub>2</sub>Se material, which is 2–3 orders higher than spark plasma sintering (SPS) samples. Theoretical analysis demonstrates that the peak pressure exceeds 4.5 GPa, while the effective pressure duration reaches 198 ns, with the impact depth exceeding 0.5 mm and the strain rate reaching 1.52 × 10<sup>7</sup> s<sup>–1</sup>. The introduction of dense dislocations via laser shock reduced the total thermal conductivity by 23.2% and the lattice thermal conductivity by 17.1%. Using a double-sided shock strategy achieved a <i>zT</i> of 0.91, a 40% increase over the SPS samples. This work demonstrates the effectiveness of LSDP in constructing dense dislocations in brittle thermoelectric materials.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"125 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145732449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-12DOI: 10.1021/acs.nanolett.5c04648
K. Hecker, S. Möller, H. Dulisch, Ş. Duman, L. Stecher, L. Valerius, T. Deußen, S. Ravuri, K. Watanabe, T. Taniguchi, F. Libisch, C. Volk, C. Stampfer
High-fidelity detection of charge transitions in quantum dots (QDs) is a key ingredient in solid-state quantum computation. We demonstrate high-bandwidth radio-frequency charge detection in bilayer graphene quantum dots (QDs) using a capacitively coupled quantum point contact (QPC). The device design suppresses screening effects and enables a sensitive QPC-based charge readout. The QPC is arranged to maximize the readout contrast between two neighboring coupled electron and hole QDs. We apply the readout scheme to a single-particle electron–hole double QD and demonstrate time-resolved detection of charge states as well as magnetic field dependent tunneling rates. This promises a high-fidelity readout scheme for individual spin and valley states, which is important for the operation of spin, valley, or spin-valley qubits in bilayer graphene.
{"title":"Radio-Frequency Charge Detection on Graphene Electron–Hole Double Quantum Dots","authors":"K. Hecker, S. Möller, H. Dulisch, Ş. Duman, L. Stecher, L. Valerius, T. Deußen, S. Ravuri, K. Watanabe, T. Taniguchi, F. Libisch, C. Volk, C. Stampfer","doi":"10.1021/acs.nanolett.5c04648","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c04648","url":null,"abstract":"High-fidelity detection of charge transitions in quantum dots (QDs) is a key ingredient in solid-state quantum computation. We demonstrate high-bandwidth radio-frequency charge detection in bilayer graphene quantum dots (QDs) using a capacitively coupled quantum point contact (QPC). The device design suppresses screening effects and enables a sensitive QPC-based charge readout. The QPC is arranged to maximize the readout contrast between two neighboring coupled electron and hole QDs. We apply the readout scheme to a single-particle electron–hole double QD and demonstrate time-resolved detection of charge states as well as magnetic field dependent tunneling rates. This promises a high-fidelity readout scheme for individual spin and valley states, which is important for the operation of spin, valley, or spin-valley qubits in bilayer graphene.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"14 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145732454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-12DOI: 10.1021/acs.nanolett.5c04336
Si Li Wu,Zhi-Hui Ren,Liu Yang,Mao-Yuan Wang,Xian-Peng Zhang,Xiao-Yue Fan,Hao-Chen Zhang,Xiang Li,Gang Wang,Chong Wang,Chuan Li,Zhi-Wei Wang,Cai-Zhen Li,Zhi-Min Liao,Yu-Gui Yao
The magnetic field-free Josephson diode effect (JDE) offers a promising route toward nonreciprocal superconducting devices, yet its microscopic origin and effective control remain unclear. Here, we demonstrate a tunable field-free JDE in NbSe2/Nb3Cl8/NbSe2 van der Waals (vdW) Josephson junctions. By reducing the Nb3Cl8 barrier thickness from four-layer to monolayer, the diode efficiency is significantly enhanced from 1.75% to 20.88%. Moreover, the diode efficiency can be effectively modulated by an out-of-plane electric field, indicating the presence of intrinsic electric polarization in the junction. Both thickness variation and electric field tuning modify the polarization strength, thereby enabling broad control of the diode efficiency. These results uncover the crucial role of intrinsic electric polarization in realizing the field-free JDE and establish this effect as a sensitive probe of spontaneous time-reversal symmetry breaking in superconducting heterostructures.
无磁场约瑟夫森二极管效应（JDE）为非互易超导器件提供了一条有希望的途径，但其微观起源和有效控制尚不清楚。在这里，我们展示了在NbSe2/Nb3Cl8/NbSe2 van der Waals (vdW) Josephson结中可调谐的无场JDE。通过将Nb3Cl8势垒厚度从四层减小到单层，二极管效率从1.75%显著提高到20.88%。此外，二极管的效率可以被一个面外电场有效地调制，这表明在结中存在本征电极化。厚度变化和电场调谐都可以改变极化强度，从而实现对二极管效率的广泛控制。这些结果揭示了本征电极化在实现无场JDE中的关键作用，并将其作为超导异质结构中自发时间反转对称性破缺的敏感探针。
{"title":"Efficiency-Tunable Field-Free Josephson Diode Effect in Nb3Cl8 Based van der Waals Junctions.","authors":"Si Li Wu,Zhi-Hui Ren,Liu Yang,Mao-Yuan Wang,Xian-Peng Zhang,Xiao-Yue Fan,Hao-Chen Zhang,Xiang Li,Gang Wang,Chong Wang,Chuan Li,Zhi-Wei Wang,Cai-Zhen Li,Zhi-Min Liao,Yu-Gui Yao","doi":"10.1021/acs.nanolett.5c04336","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c04336","url":null,"abstract":"The magnetic field-free Josephson diode effect (JDE) offers a promising route toward nonreciprocal superconducting devices, yet its microscopic origin and effective control remain unclear. Here, we demonstrate a tunable field-free JDE in NbSe2/Nb3Cl8/NbSe2 van der Waals (vdW) Josephson junctions. By reducing the Nb3Cl8 barrier thickness from four-layer to monolayer, the diode efficiency is significantly enhanced from 1.75% to 20.88%. Moreover, the diode efficiency can be effectively modulated by an out-of-plane electric field, indicating the presence of intrinsic electric polarization in the junction. Both thickness variation and electric field tuning modify the polarization strength, thereby enabling broad control of the diode efficiency. These results uncover the crucial role of intrinsic electric polarization in realizing the field-free JDE and establish this effect as a sensitive probe of spontaneous time-reversal symmetry breaking in superconducting heterostructures.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"38 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145728651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zinc–nitrite batteries (ZNBs) can simultaneously supply energy and produce ammonia, yet their practical use is limited by the sluggish kinetics of the oxygen evolution reaction (OER) and nitrite reduction reaction (NitRR). Herein, we developed energy-saving zinc–hydrazine/nitrite batteries (ZHNBs) that replace the sluggish OER with the favorable hydrazine oxidation reaction (HzOR) using Al–Ni2P nanoflowers as catalysts. The optimized ZHNBs employing Al0.1-Ni2P/NF achieved an ultranarrow charging-discharge voltage gap of 0.59 V, an extended cycle life of 300 h, and a high NH3 yield of 304 μmol h–1 cm–2, significantly outperforming conventional ZNBs. Mechanistic studies revealed that dopant-induced lattice expansion in Ni2P dominantly governs the HzOR by enhancing N2H4 adsorption and reducing structural relaxation, while electronic redistribution enhances the NitRR by controlling active H* intermediates, with both effects synergistically improving battery efficiency. This dual-modulation strategy of geometry and electronic structures via doping offers a general approach for designing advanced nanocatalysts in energy devices.
锌-亚硝酸盐电池（ZNBs）可以同时提供能量和产生氨，但其实际应用受到析氧反应（OER）和亚硝酸盐还原反应（NitRR）动力学缓慢的限制。本研究以Al-Ni2P纳米花为催化剂，开发了以良好的肼氧化反应（HzOR）取代缓慢的OER的节能型锌-肼/亚硝酸盐电池（ZHNBs）。采用Al0.1-Ni2P/NF制备的ZHNBs具有0.59 V的超窄充放电电压隙、300 h的循环寿命和304 μmol h - 1 cm-2的NH3产率，显著优于传统的znb。机理研究表明，掺杂剂诱导的Ni2P晶格膨胀主要通过增强N2H4吸附和减少结构弛豫来控制HzOR，而电子再分布通过控制活性H*中间体来增强NitRR，两者协同作用提高电池效率。这种通过掺杂实现几何结构和电子结构的双调制策略为设计先进的能源器件纳米催化剂提供了一种通用的方法。
{"title":"Rechargeable Zinc–Hydrazine/Nitrite Batteries Catalyzed by Al-Doped Ni2P Nanoflowers for Energy Supply and NH3 Electrosynthesis","authors":"Xian-Wei Lv, Jiaxing Gong, Xiaodong Meng, Shang Chen, Manyun Wang, Yuping Liu, Zhuangzhuang Lai, Haifeng Wang, Zhong-Yong Yuan, Jianxin Geng","doi":"10.1021/acs.nanolett.5c04603","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c04603","url":null,"abstract":"Zinc–nitrite batteries (ZNBs) can simultaneously supply energy and produce ammonia, yet their practical use is limited by the sluggish kinetics of the oxygen evolution reaction (OER) and nitrite reduction reaction (NitRR). Herein, we developed energy-saving zinc–hydrazine/nitrite batteries (ZHNBs) that replace the sluggish OER with the favorable hydrazine oxidation reaction (HzOR) using Al–Ni<sub>2</sub>P nanoflowers as catalysts. The optimized ZHNBs employing Al<sub>0.1</sub>-Ni<sub>2</sub>P/NF achieved an ultranarrow charging-discharge voltage gap of 0.59 V, an extended cycle life of 300 h, and a high NH<sub>3</sub> yield of 304 μmol h<sup>–1</sup> cm<sup>–2</sup>, significantly outperforming conventional ZNBs. Mechanistic studies revealed that dopant-induced lattice expansion in Ni<sub>2</sub>P dominantly governs the HzOR by enhancing N<sub>2</sub>H<sub>4</sub> adsorption and reducing structural relaxation, while electronic redistribution enhances the NitRR by controlling active H* intermediates, with both effects synergistically improving battery efficiency. This dual-modulation strategy of geometry and electronic structures via doping offers a general approach for designing advanced nanocatalysts in energy devices.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"29 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145732452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-12DOI: 10.1021/acs.nanolett.5c05030
Jose M. Abad, Marcos Pita, Antonio L. De Lacey, Alonso Gamero-Quijano
Functional enzyme–gold nanoparticle bioconjugates are becoming increasingly important in bioelectrocatalysis since they facilitate and improve the efficiency of long-range protein interfacial electron transfer between enzymes and electrodes by enhancing conductivity. While much research has focused on solid–liquid interfaces, there is still limited understanding of the key parameters and electrochemical conditions necessary for reliable and reproducible bioelectrochemistry at polarizable aqueous–organic interfaces under native conditions. Herein, we demonstrate how the size of gold-modified nanoparticles influences the interfacial electron transfer of cytochrome c at an aqueous–organic interface. We found that nanoclusters centered in a size of 1.2 nm, equivalent to the water-trifluorotoluene mixed solvent layer (ca. 1.5 nm), work in tandem with cytochrome c to facilitate oxygen reduction reactions. In contrast, bioconjugates comprising larger gold nanoparticles are less effective in enhancing cytochrome c electrochemistry, with the gold nanoparticles acting as independent catalysts at the interface.
{"title":"Gold Nanocluster-Promoted Interfacial Electron Transfer of Cytochrome c at an Aqueous–Organic Interface","authors":"Jose M. Abad, Marcos Pita, Antonio L. De Lacey, Alonso Gamero-Quijano","doi":"10.1021/acs.nanolett.5c05030","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c05030","url":null,"abstract":"Functional enzyme–gold nanoparticle bioconjugates are becoming increasingly important in bioelectrocatalysis since they facilitate and improve the efficiency of long-range protein interfacial electron transfer between enzymes and electrodes by enhancing conductivity. While much research has focused on solid–liquid interfaces, there is still limited understanding of the key parameters and electrochemical conditions necessary for reliable and reproducible bioelectrochemistry at polarizable aqueous–organic interfaces under native conditions. Herein, we demonstrate how the size of gold-modified nanoparticles influences the interfacial electron transfer of cytochrome c at an aqueous–organic interface. We found that nanoclusters centered in a size of 1.2 nm, equivalent to the water-trifluorotoluene mixed solvent layer (ca. 1.5 nm), work in tandem with cytochrome c to facilitate oxygen reduction reactions. In contrast, bioconjugates comprising larger gold nanoparticles are less effective in enhancing cytochrome c electrochemistry, with the gold nanoparticles acting as independent catalysts at the interface.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"72 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145732523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-11DOI: 10.1021/acs.nanolett.5c04269
Bingxin Liu, William D. Stuart, Iris M. Fink-Baldauf, Elisa Boscolo, Mari Mino-Kenudson, Eric L. Snyder, Yutaka Maeda
We have recently developed polymer/lipid nanoparticles PBAE-PEG/4A3-SC8/DOPE/Cholesterol/DOTAP (hereafter, PBAE-PEG/LNP) that can deliver mRNA into lung cells. Here, using PBAE-PEG/LNP, we delivered Cre mRNA and/or sgRNAs into KrasLSL-G12D/+ and/or Cas9 mice to develop genetically engineered lung cancer mouse models. PBAE-PEG/LNP delivery of Cre mRNA into KrasLSL-G12D/+;Cas9 mice by intratracheal (IT) injection produced autochthonous lung tumors while intravenous injection resulted in lung tumors as well as bronchus-associated lymphoid tissue (BALT). PBAE-PEG/LNP delivery of Cre mRNA along with sgRNA targeting the lung lineage transcription factor Nkx2-1 (sgNkx2-1) into KrasLSL-G12D/+;Cas9 mice by IT injection produced autochthonous invasive mucinous adenocarcinoma of the lung (IMA) that lacks NKX2-1 while expressing the gastrointestinal transcription factor HNF4A. PBAE-PEG/LNP delivery of sgRNAs targeting Eml4 (sgEml4) and Alk (sgAlk) into Cas9 mice by IT injection produced autochthonous lung tumors carrying the driver oncogene Eml4-Alk. This approach using PBAE-PEG/LNP to deliver RNA will allow for agile development of lung cancer mouse models.
{"title":"PBAE-PEG/Lipid Nanoparticle Delivery of RNA for the Creation of Genetically Engineered Lung Cancer Mouse Models","authors":"Bingxin Liu, William D. Stuart, Iris M. Fink-Baldauf, Elisa Boscolo, Mari Mino-Kenudson, Eric L. Snyder, Yutaka Maeda","doi":"10.1021/acs.nanolett.5c04269","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c04269","url":null,"abstract":"We have recently developed polymer/lipid nanoparticles PBAE-PEG/4A3-SC8/DOPE/Cholesterol/DOTAP (hereafter, PBAE-PEG/LNP) that can deliver mRNA into lung cells. Here, using PBAE-PEG/LNP, we delivered <i>Cre</i> mRNA and/or sgRNAs into <i>Kras</i><sup><i>LSL-G12D/+</i></sup> and/or <i>Cas9</i> mice to develop genetically engineered lung cancer mouse models. PBAE-PEG/LNP delivery of <i>Cre</i> mRNA into <i>Kras</i><sup><i>LSL-G12D/+</i></sup><i>;Cas9</i> mice by intratracheal (IT) injection produced autochthonous lung tumors while intravenous injection resulted in lung tumors as well as bronchus-associated lymphoid tissue (BALT). PBAE-PEG/LNP delivery of <i>Cre</i> mRNA along with sgRNA targeting the lung lineage transcription factor <i>Nkx2-1</i> (sgNkx2-1) into <i>Kras</i><sup><i>LSL-G12D/+</i></sup><i>;Cas9</i> mice by IT injection produced autochthonous invasive mucinous adenocarcinoma of the lung (IMA) that lacks NKX2-1 while expressing the gastrointestinal transcription factor HNF4A. PBAE-PEG/LNP delivery of sgRNAs targeting <i>Eml4</i> (sgEml4) and <i>Alk</i> (sgAlk) into <i>Cas9</i> mice by IT injection produced autochthonous lung tumors carrying the driver oncogene <i>Eml4-Alk</i>. This approach using PBAE-PEG/LNP to deliver RNA will allow for agile development of lung cancer mouse models.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"113 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145718322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
White phosphorescent materials are highly desirable for delayed lighting and advanced display applications; however, their development is hindered by time-dependent spectral changes and low efficiency. Herein, we report bright and long-lived white phosphorescence from carbon nanodots (CNDs) achieved by synchronizing excited-state lifetime engineering yielding white phosphorescent CNDs with a lifetime of 800 ms and a quantum efficiency of 27.9%. A secondary carbonization strategy synchronizes multiple emission centers, enabling stable white phosphorescence over 6 s, tunable correlated color temperature (4400–7990 K), and CIE coordinates (0.29, 0.32) to (0.36, 0.34). Moreover, integration of these CNDs into a light emitting diode (LED) demonstrates delayed white emission with suppressed flicker under alternating-current excitation, providing eye-friendly illumination. Programmable delayed LED arrays reconstruct temporally fragmented signals into coherent images. This work demonstrates a robust strategy for bright and long-lasting white phosphorescent materials, laying the foundation for advanced delayed lighting and programmable display applications.
{"title":"Synchronizing Excited-State Lifetimes for Bright and Long-Lived White Phosphorescent Carbon Nanodots","authors":"Xiang-Yu Li, Si-Tao Liu, Qing Cao, Shi-Yu Song, Meng-Di Gao, Chao-Jun Gao, Wen-Shuo Zhang, Wen-Bo Zhao, Chong-Xin Shan, Kai-Kai Liu","doi":"10.1021/acs.nanolett.5c05349","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c05349","url":null,"abstract":"White phosphorescent materials are highly desirable for delayed lighting and advanced display applications; however, their development is hindered by time-dependent spectral changes and low efficiency. Herein, we report bright and long-lived white phosphorescence from carbon nanodots (CNDs) achieved by synchronizing excited-state lifetime engineering yielding white phosphorescent CNDs with a lifetime of 800 ms and a quantum efficiency of 27.9%. A secondary carbonization strategy synchronizes multiple emission centers, enabling stable white phosphorescence over 6 s, tunable correlated color temperature (4400–7990 K), and CIE coordinates (0.29, 0.32) to (0.36, 0.34). Moreover, integration of these CNDs into a light emitting diode (LED) demonstrates delayed white emission with suppressed flicker under alternating-current excitation, providing eye-friendly illumination. Programmable delayed LED arrays reconstruct temporally fragmented signals into coherent images. This work demonstrates a robust strategy for bright and long-lasting white phosphorescent materials, laying the foundation for advanced delayed lighting and programmable display applications.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"6 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145718324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-11DOI: 10.1021/acs.nanolett.5c04719
Xiaoyu Zhang,Yi Liu,Mengqi Wang,Xiaoxin Guo,Jun Yu,Jiayi Wei,Xiangjia Ge,Yuqing Liu,Jinyou Lin
Piezoelectric nanogenerators (PENGs) are promising for efficient nanoenergy harvesting, yet their output is often limited by disruption of the active phase by nonpolar phases. Here, we introduce a postelectrospinning hot-stretching treatment after conjugated electrospinning to precisely regulate the microcrystalline morphology of a poly(vinylidene fluoride) (PVDF) nanofiber yarn (NY). This strategy increased the lamellar long period and lateral size of the resultant NY, yielding a highly regular crystalline structure with ∼60% crystallinity and ∼93% β-phase content. Consequently, the optimized PVDF NY achieved a fracture stress of 65 MPa, a 444% improvement over the pristine sample. The piezoelectric output also rose by 366.7%, from 0.3 to 1.4 V. These enhancements highlight hot stretching as an effective approach to simultaneously improving the mechanical and electrical properties of a PVDF NY. This work provides a new pathway for developing high-performance PENGs with significant potential in sustainable energy-harvesting applications.
{"title":"Microstructural Engineering of Poly(vinylidene fluoride) Nanofibers Enables Superior Piezoelectric Nanogenerators for Motion Monitoring.","authors":"Xiaoyu Zhang,Yi Liu,Mengqi Wang,Xiaoxin Guo,Jun Yu,Jiayi Wei,Xiangjia Ge,Yuqing Liu,Jinyou Lin","doi":"10.1021/acs.nanolett.5c04719","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c04719","url":null,"abstract":"Piezoelectric nanogenerators (PENGs) are promising for efficient nanoenergy harvesting, yet their output is often limited by disruption of the active phase by nonpolar phases. Here, we introduce a postelectrospinning hot-stretching treatment after conjugated electrospinning to precisely regulate the microcrystalline morphology of a poly(vinylidene fluoride) (PVDF) nanofiber yarn (NY). This strategy increased the lamellar long period and lateral size of the resultant NY, yielding a highly regular crystalline structure with ∼60% crystallinity and ∼93% β-phase content. Consequently, the optimized PVDF NY achieved a fracture stress of 65 MPa, a 444% improvement over the pristine sample. The piezoelectric output also rose by 366.7%, from 0.3 to 1.4 V. These enhancements highlight hot stretching as an effective approach to simultaneously improving the mechanical and electrical properties of a PVDF NY. This work provides a new pathway for developing high-performance PENGs with significant potential in sustainable energy-harvesting applications.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"7 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145728657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-11DOI: 10.1021/acs.nanolett.5c04848
SangJae Lee, HyunWoo J. Yang, HyunWoo Chang, Junu Bak, DongWon Shin, EunAe Cho
Platinum–copper alloy nanosheets supported on carbon (PtCu NS/C) with well-defined (111) facets were synthesized via a scalable one-pot method, yielding ultrathin structures with thicknesses of ∼1 nm and lateral sizes of ∼10–15 nm. As catalysts for the oxygen reduction reaction (ORR), PtCu NS/C exhibited superior performance and durability compared to those of PtCu octahedral nanoparticles (PtCu NP/C) and commercial Pt/C. In half-cell measurements, PtCu NS/C achieved a mass activity of 5.61 A mgPt–1 at 0.9 VRHE and an electrochemically active surface area (ECSA) of 94 m2 gPt–1, significantly surpassing those of PtCu NP/C and Pt/C. In polymer electrolyte membrane fuel cells (PEMFCs), PtCu NS/C delivered a current density of 48 mA cm–2 at 0.8 V, retaining 31 mA cm–2 after 50 000 accelerated stress test cycles. The outstanding activity and stability are attributed to the nanosheet architecture, which provides a high surface-to-volume ratio, abundant (111) surface atoms, enhanced Pt utilization, and an enlarged interfacial contact region with the carbon support. These findings highlight the potential of two-dimensional PtCu nanosheets as highly efficient and durable ORR catalysts for PEMFCs.
通过可扩展的一锅法合成了具有良好定义（111）面的碳（PtCu NS/C）支撑的铂铜合金纳米片，得到了厚度为~ 1 nm，横向尺寸为~ 10-15 nm的超薄结构。作为氧还原反应（ORR）的催化剂，PtCu NS/C比PtCu八面体纳米粒子（PtCu NP/C）和商用Pt/C表现出更优异的性能和耐久性。在半电池测量中，PtCu NS/C在0.9 VRHE下的质量活性为5.61 a mgPt-1，电化学活性表面积（ECSA）为94 m2 gPt-1，显著超过PtCu NP/C和Pt/C。在聚合物电解质膜燃料电池（pemfc）中，PtCu NS/C在0.8 V下提供48 mA cm-2的电流密度，在50 000次加速应力测试循环后保持31 mA cm-2。优异的活性和稳定性归功于纳米片结构，它提供了高的表面体积比，丰富的（111）表面原子，提高了铂的利用率，并扩大了与碳载体的界面接触区域。这些发现突出了二维PtCu纳米片作为pemfc高效耐用的ORR催化剂的潜力。
{"title":"Ultrathin PtCu Nanosheets: A New Frontier in Highly Efficient and Durable Catalysts for the Oxygen Reduction Reaction","authors":"SangJae Lee, HyunWoo J. Yang, HyunWoo Chang, Junu Bak, DongWon Shin, EunAe Cho","doi":"10.1021/acs.nanolett.5c04848","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c04848","url":null,"abstract":"Platinum–copper alloy nanosheets supported on carbon (PtCu NS/C) with well-defined (111) facets were synthesized via a scalable one-pot method, yielding ultrathin structures with thicknesses of ∼1 nm and lateral sizes of ∼10–15 nm. As catalysts for the oxygen reduction reaction (ORR), PtCu NS/C exhibited superior performance and durability compared to those of PtCu octahedral nanoparticles (PtCu NP/C) and commercial Pt/C. In half-cell measurements, PtCu NS/C achieved a mass activity of 5.61 A mg<sub>Pt</sub><sup>–1</sup> at 0.9 V<sub>RHE</sub> and an electrochemically active surface area (ECSA) of 94 m<sup>2</sup> g<sub>Pt</sub><sup>–1</sup>, significantly surpassing those of PtCu NP/C and Pt/C. In polymer electrolyte membrane fuel cells (PEMFCs), PtCu NS/C delivered a current density of 48 mA cm<sup>–2</sup> at 0.8 V, retaining 31 mA cm<sup>–2</sup> after 50 000 accelerated stress test cycles. The outstanding activity and stability are attributed to the nanosheet architecture, which provides a high surface-to-volume ratio, abundant (111) surface atoms, enhanced Pt utilization, and an enlarged interfacial contact region with the carbon support. These findings highlight the potential of two-dimensional PtCu nanosheets as highly efficient and durable ORR catalysts for PEMFCs.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"56 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145718323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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