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Life cycle assessment of an isolated hybrid micro-grid with hydrogen production and storage 具有制氢和储氢功能的孤立混合微电网的生命周期评估。
IF 5.8 3区 环境科学与生态学 0 ENVIRONMENTAL SCIENCES Pub Date : 2025-11-22 DOI: 10.1007/s11356-025-36924-0
Ravi Nath Tiwari, Henri Schneider, Catherine Azzaro-Pantel, Chandrakala Mishra, Ahmed G. Elkafas, Aristide Fausto Massardo

The world’s rapid advancements have increased energy demand, necessitating both traditional and alternative sources. Non-renewable energy sources contribute to greenhouse gas emissions, prompting urgency to address climate change. The study explores the implementation of a hybrid energy microgrid system for a mountain shelter “refuge” in southern France, aiming to reduce environmental impact. The system uses photovoltaics, electrolysers, and batteries, focuses on hydrogen production and storage, as well as renewable electric power generation. The study compares the environmental impacts of the hybrid system and conventional energy systems, focusing on the impact of photovoltaic module production both globally and locally in France. The study highlights the importance of renewable energy sources in reducing environmental impact. A study using SimaPro and the ecoinvent database found that PV arrays account for 97% of environmental impacts, while other components contribute to 3%. Locally manufactured microgrids in France reduced environmental impact by 39% compared to standard systems. The PV system and electrolyser in a mountain shelter showed favourable environmental and economic outcomes. The study emphasizes the importance of local manufacturing locations and electricity mix for PV module manufacturers.

世界的快速发展增加了能源需求,需要传统和替代能源。不可再生能源导致温室气体排放,应对气候变化迫在眉睫。该研究探索了法国南部山区避难所“避难所”混合能源微电网系统的实施,旨在减少对环境的影响。该系统使用光伏、电解槽和电池,专注于氢气的生产和储存,以及可再生能源发电。该研究比较了混合系统和传统能源系统对环境的影响,重点是光伏组件生产对全球和法国当地的影响。这项研究强调了可再生能源在减少环境影响方面的重要性。一项使用SimaPro和ecoinvent数据库的研究发现,光伏阵列占环境影响的97%,而其他组件只占3%。与标准系统相比,法国本地制造的微电网减少了39%的环境影响。在山间掩蔽处的光伏系统和电解槽显示出良好的环境和经济效益。该研究强调了当地制造地点和电力组合对光伏组件制造商的重要性。
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引用次数: 0
Carbonation of steel slag for mineral CO2 sequestration: a novel method for desorption of CO2-loaded monoethanolamine (MEA) 钢渣碳化固载矿物CO2:一种载CO2单乙醇胺解吸的新方法。
IF 5.8 3区 环境科学与生态学 0 ENVIRONMENTAL SCIENCES Pub Date : 2025-11-22 DOI: 10.1007/s11356-025-37220-7
Ayşegül Bilen Özkan, Mert Altay, Erdal Ünal, Oğuz Gündüz

This study presents a novel method for integrating amine-based CO₂ capture with mineral carbonation by using steelmaking slag to regenerate monoethanolamine (MEA) solutions. Unlike conventional thermal desorption methods, this approach enables chemical CO₂ desorption under mild conditions while simultaneously sequestering CO₂ as stable carbonates. Although mineral carbonation and MEA-based capture have been widely studied separately, their combination via reactive calcium-rich industrial waste remains largely unexplored. In this work, steel slag was contacted with CO₂-loaded MEA solutions to assess its dual role in promoting CO₂ release and mineralization. The effects of key process parameters—including slag-to-water ratio, CO₂ flow rate, temperature (25–75 °C), MEA concentration (0–0.5 M), and water type (service vs. seawater)—were systematically evaluated. Carbonation efficiency was quantified via TGA, XRF, and XRD analyses. Results showed that MEA significantly enhanced CO₂ uptake and accelerated carbonate formation, especially at higher temperatures and in seawater. Kinetic modeling revealed that the reaction follows a mixed-controlled mechanism involving both surface reaction and product-layer diffusion, with an apparent activation energy of 5.6 kJ/mol. The study demonstrates the feasibility of combining CO₂ desorption and mineralization in a single step, offering a low-energy alternative to MEA regeneration and a sustainable use for steel slag in CO₂ capture systems.

本研究提出了一种利用炼钢渣再生单乙醇胺(MEA)溶液,将胺基CO 2捕集与矿物碳化相结合的新方法。与传统的热解吸方法不同,这种方法可以在温和的条件下进行化学CO₂解吸,同时将CO₂作为稳定的碳酸盐隔离。尽管矿物碳酸化和基于mea的捕集已经分别进行了广泛的研究,但它们通过活性富钙工业废物的组合在很大程度上仍未被探索。在这项工作中,钢渣与CO₂负载的MEA溶液接触,以评估其促进CO₂释放和矿化的双重作用。系统评估了关键工艺参数的影响,包括渣水比、CO 2流量、温度(25-75℃)、MEA浓度(0-0.5 M)和水类型(服务与海水)。通过TGA, XRF和XRD分析量化碳化效率。结果表明,MEA显著提高了CO 2的吸收,加速了碳酸盐的形成,特别是在高温和海水中。动力学模拟表明,该反应遵循表面反应和产物层扩散的混合控制机制,表观活化能为5.6 kJ/mol。该研究证明了将CO 2解吸和矿化在一个步骤中结合的可行性,为MEA再生提供了一种低能耗替代方案,并在CO 2捕集系统中可持续利用钢渣。
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引用次数: 0
Advances in separation processes for sustainable solutions in energy and environment. 分离工艺在能源和环境可持续解决方案中的进展。
IF 5.8 3区 环境科学与生态学 0 ENVIRONMENTAL SCIENCES Pub Date : 2025-11-22 DOI: 10.1007/s11356-025-37230-5
Zakaria Al-Qodah, Guilherme Luiz Dotto, Reyad Shawabkeh, Ahmad T Shawaqfeh, Mohammad Al-Shannag
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引用次数: 0
Anode surface modification with reduced graphene oxide (rGO) and molybdenum (Mo) enhances microbial diversity and chemical oxygen demand (COD) removal in microbial fuel cells 用还原氧化石墨烯(rGO)和钼(Mo)修饰阳极表面可增强微生物燃料电池中的微生物多样性和化学需氧量(COD)去除。
IF 5.8 3区 环境科学与生态学 0 ENVIRONMENTAL SCIENCES Pub Date : 2025-11-21 DOI: 10.1007/s11356-025-37243-0
Habib Akyazı, Fatma Çiğdem Güldür, Ebru Beyzi

This study aimed to investigate the effects of anode surface modifications on microbial community composition and chemical oxygen demand (COD) removal efficiency in microbial fuel cells (MFCs). Four different anode electrodes were fabricated: bare nickel foam (NF), reduced graphene oxide-coated nickel foam (rGO/NF), and rGO/NF modified with 30 wt% and 50 wt% molybdenum (Mo). These electrodes were tested in a single-chamber, membraneless, air–cathode MFC. Surface morphology was characterized using scanning electron microscopy (SEM), and microbial diversity was assessed through 16S rRNA metagenomic sequencing. Distinct microbial profiles were observed across the electrode types. The NF anode supported high abundances of Mesoterricola sediminis (22.2%), Klebsiella pneumoniae (10.1%), and other facultative species. The rGO/NF electrode promoted colonization by Cutibacterium acnes (8.1%) and Paracidovorax avenae (5.4%). On the 30Mo/rGO/NF electrode, notable species included Escherichia coli (8.4%) and Salmonella enterica (6.0%). The 50Mo/rGO/NF anode exhibited the highest microbial diversity, with species such as Streptomyces sp. RerS4 (6.9%) and Micromonospora endophytica (6.5%) being predominant. The highest COD removal efficiency (88.58%) was achieved using the 50Mo/rGO/NF anode. These findings demonstrate that molybdenum-modified rGO coatings enhance both microbial colonization and electrochemical performance, offering a promising strategy for improving MFC efficiency in wastewater treatment applications.

Graphical Abstract

本研究旨在探讨阳极表面改性对微生物燃料电池(mfc)微生物群落组成和化学需氧量(COD)去除效率的影响。制备了四种不同的阳极电极:裸泡沫镍(NF),还原氧化石墨烯包覆泡沫镍(rGO/NF),以及用30% wt%和50% Mo修饰的rGO/NF。这些电极在单室无膜空气阴极MFC中进行测试。利用扫描电镜(SEM)对表面形貌进行了表征,并通过16S rRNA宏基因组测序对微生物多样性进行了评估。在不同的电极类型中观察到不同的微生物特征。NF阳极支持高丰度的沉积中陆生菌(22.2%)、肺炎克雷伯菌(10.1%)和其他兼性菌。rGO/NF电极促进痤疮表皮杆菌(8.1%)和avenacidovorax(5.4%)的定植。在30Mo/rGO/NF电极上,大肠杆菌(8.4%)和肠沙门氏菌(6.0%)是显著的菌种。50Mo/rGO/NF阳极微生物多样性最高,以链霉菌(Streptomyces sp. RerS4)(6.9%)和内生小单孢子菌(Micromonospora endophytica)(6.5%)为主。50Mo/rGO/NF阳极的COD去除率最高,达到88.58%。这些发现表明,钼改性氧化石墨烯涂层增强了微生物定植和电化学性能,为提高废水处理中MFC的效率提供了一个有前途的策略。
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引用次数: 0
A campaign-based study on the physio-chemical characterization and source apportionment of particulate matter in the Central Himalayas 基于运动的喜马拉雅中部颗粒物理化特征及来源解析研究。
IF 5.8 3区 环境科学与生态学 0 ENVIRONMENTAL SCIENCES Pub Date : 2025-11-21 DOI: 10.1007/s11356-025-37217-2
Vikas Rawat, Narendra Singh, Surendra K. Dhaka, Prashant K. Chauhan, Jagdish C. Kuniyal, Prity S. Pippal, Sanjeev Kimothi, Mayank Kumar Chauhan

This study presents the first campaign-based assessment of the physio-chemical characteristics, sources, and health risks of particulate matter (PM2.5 and PM10) across Uttarakhand state in the Central Himalaya, India. Spanning 13 districts across diverse geographical features during winter and summer with a low volume PM sampler, the research integrates advanced analytical techniques (XRD, SEM–EDX, ICP-MS) with receptor modeling (Positive Matrix Factorization) and health risk assessment. Results reveal significant spatial and seasonal variability: PM2.5 (20–125 µg/m3) and PM10 (25–190 µg/m3) concentrations frequently exceeded WHO guidelines, with higher PM2.5/PM10 ratios (0.48–0.72) in winter indicating anthropogenic dominance, while summer showed stronger crustal influences. Aerosol optical depth (380-1020 nm) was lower at high-altitude sites (0.24–0.46), with spectral anomalies at 936 nm highlighting absorbing aerosols (e.g., black carbon, mineral dust). Mixed aerosols (58%) dominated over dust (18%) and biomass burning (7%). XRD identified carcinogenic quartz and hematite, alongside crustal and industrial minerals (kaolinite, gypsum, calcite etc.). SEM–EDX revealed diverse particle morphologies, with C, O, Si, and Al as dominant elements. PMF source apportionment (ICP-MS) traced PM10 primarily to mineral dust (41.7%) and combustion activities (34.5%), and PM2.5 to biomass burning (12.3%) and dust (51.1%). Enrichment factors and health risk assessments indicated potential non-carcinogenic risks (especially for children) from Cd and Al, and carcinogenic risks from Cr. This study highlights the need for targeted mitigation strategies and future research, incorporating a wider range of PM constituents (ions, carbonaceous aerosols, PAHs, trace gases) for a comprehensive understanding of aerosol impacts in the region.

本研究首次以运动为基础,对印度喜马拉雅中部北阿坎德邦的颗粒物(PM2.5和PM10)的理化特征、来源和健康风险进行了评估。该研究在冬季和夏季跨越13个不同地理特征的地区,采用小体积PM采样器,将先进的分析技术(XRD, SEM-EDX, ICP-MS)与受体建模(正矩阵分解)和健康风险评估相结合。结果显示了显著的空间和季节变化:PM2.5(20-125µg/m3)和PM10(25-190µg/m3)浓度经常超过世卫组织指南,冬季PM2.5/PM10比值较高(0.48-0.72),表明人为因素占主导地位,而夏季地壳影响较强。在高海拔地区,气溶胶光学深度(380-1020 nm)较低(0.24-0.46 nm),在936 nm处的光谱异常突出了吸收气溶胶(如黑碳、矿物粉尘)。混合气溶胶(58%)超过粉尘(18%)和生物质燃烧(7%)。XRD鉴定出了致癌的石英和赤铁矿,以及地壳和工业矿物(高岭石、石膏、方解石等)。SEM-EDX显示了不同的颗粒形态,以C, O, Si和Al为主导元素。PMF源解析(ICP-MS)主要追踪到矿物粉尘(41.7%)和燃烧活动(34.5%),PM2.5主要追踪到生物质燃烧(12.3%)和粉尘(51.1%)。富集因子和健康风险评估表明,Cd和Al的潜在非致癌性风险(特别是对儿童)以及Cr的致癌风险。本研究强调需要有针对性的缓解策略和未来的研究,纳入更广泛的PM成分(离子、碳质气溶胶、多环芳烃、微量气体),以全面了解该地区的气溶胶影响。
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引用次数: 0
Low-rate trickling filter with natural ventilation: diagnosis in a full-scale WWTP set in southern Brazil 具有自然通风的低速率滴流过滤器:在巴西南部全尺寸污水处理厂的诊断。
IF 5.8 3区 环境科学与生态学 0 ENVIRONMENTAL SCIENCES Pub Date : 2025-11-21 DOI: 10.1007/s11356-025-36921-3
Bruna Rocha de Oliveira-Avellar, Kawany Marçal, Guilherme Alves dos Santos, Cleverson Roberto Bogo, Renato Pereira Ribeiro, Miguel Mansur Aisse

The upflow anaerobic sludge blanket (UASB) reactor effectively removes organic matter from wastewater but does not remove ammoniacal nitrogen, which harms aquatic life in water bodies when in excess. The trickling filter (TF) has been used in Brazil mainly as post-treatment of anaerobic effluents to remove organic carbon and residual solids. Information on N-ammonium removal in UASB–low-rate TF systems at full treatment scale is scarce. Therefore, this work aims to evaluate the performance of a wastewater treatment plant (WWTP), with stone media, featuring natural ventilation and including nighttime effluent recirculation, operating at an average flow rate of 53 L·s−1 in southern Brazil, which combines a UASB reactor and low-rate TF, as well as the transformations of N in the liquid phase of treatment. A 37-month monitoring period was conducted, along with seasonal 24-h sampling campaigns. Results showed that the system’s efficiency was above 90% for the parameters BOD, TSS, and SS, and the results for average N-ammonium removal in the low-rate TF showed a reduction of 18% when compared to the influent. In addition, nitrification was influenced by the N-ammonium load and the recirculation occurring in the system.

Graphical Abstract

上流式厌氧污泥毯(UASB)反应器能有效去除废水中的有机物,但不能去除过量的氨态氮,氨态氮对水体中的水生生物有害。在巴西,滴流过滤器主要用于厌氧废水的后处理,以去除有机碳和残余固体。关于uasb -低速率TF系统在全处理规模下去除n -铵的信息很少。因此,本研究旨在评估巴西南部一座平均流量为53 L·s-1、采用石材介质、具有自然通风和夜间污水再循环的污水处理厂(WWTP)的性能,该污水处理厂结合了UASB反应器和低速率TF,以及处理液相中N的转化。开展了为期37个月的监测期以及季节性的24小时抽样活动。结果表明,该系统在BOD、TSS和SS参数上的效率均在90%以上,在低速率TF中的平均n -铵去除率比进水降低了18%。此外,n -铵负荷和系统内发生的再循环对硝化作用也有影响。
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引用次数: 0
Metal-induced changes in the early-life gut microbial composition and life-history traits in three insectivorous passerines 金属诱导的三种食虫雀形目动物早期肠道微生物组成和生活史特征的变化。
IF 5.8 3区 环境科学与生态学 0 ENVIRONMENTAL SCIENCES Pub Date : 2025-11-21 DOI: 10.1007/s11356-025-37181-x
Miia J. Rainio, Lyydia Leino, Eero Vesterinen, Pablo Sánchez Virosta, Pere Puigbò, Tapio Eeva

Pollution-induced changes in gut microbiota may have serious effects on avian health and physiology. Particularly, early-life exposure to environmental pollutants may influence the gut microbiota development and microbiota-dependent physiological functions. We studied the associations of metal pollution with early-life microbial environment of wild passerines by exploring gut bacterial diversity and community composition in nestlings by 16S rRNA sequencing. Samples were collected from three common model species, great tits (Parus major), blue tits (Cyanistes caeruleus), and pied flycatchers (Ficedula hypoleuca) breeding near a copper-nickel smelter, an area with the highest rates of metal pollution in Finland. Responses of microbiota to pollution and microclimate were measured and connected to ecological measures (brood size, growth, fledging success) of nestling performance. The most abundant bacterial phyla across species were Firmicutes, Proteobacteria and Actinobacteria. Our results showed that the faecal microbial alpha diversity decreased with increasing brood size in great tits and blue tits, while in pied flycatchers the diversity increased with increasing nestling growth. However, alpha diversity did not differ between the polluted and control areas. The faecal microbial communities (beta diversity) differed between the species and study areas, and several bacterial orders were associated with metal concentrations, temperature, body mass, or fledging success. Differential abundance analyses showed species-specific differences in microbial abundances between polluted and control areas, e.g., Catellicoccus and Serratia showing elevated abundance within the polluted area. The results suggest that metal pollution may alter the early-life bacterial communities in small passerine species living in metal-polluted areas.

污染引起的肠道菌群变化可能对禽类健康和生理产生严重影响。特别是,生命早期暴露于环境污染物可能会影响肠道微生物群的发育和依赖微生物群的生理功能。本研究通过16S rRNA测序技术对野生雀形目动物肠道细菌多样性和群落组成进行研究,探讨金属污染与雀形目动物早期微生物环境的关系。样本来自三种常见的模式物种,即大山雀(Parus major)、蓝山雀(Cyanistes caeruleus)和斑胸蝇(Ficedula hypoleuca),它们在芬兰金属污染率最高的铜镍冶冶厂附近繁殖。测量了微生物群对污染和小气候的响应,并将其与雏鸟性能的生态指标(育雏量、生长、羽化成功)联系起来。物种间最丰富的细菌门是厚壁菌门、变形菌门和放线菌门。结果表明,大山雀和蓝山雀的粪便微生物α多样性随雏鸟数量的增加而降低,而斑衣鸟的粪便微生物α多样性随雏鸟数量的增加而增加。α多样性在污染区和控制区之间无显著差异。不同物种和研究区域的粪便微生物群落(β多样性)不同,一些细菌目与金属浓度、温度、体重或羽化成功有关。差异丰度分析显示,污染区和控制区之间的微生物丰度存在物种特异性差异,例如,卡特利球菌和沙雷氏菌在污染区内的丰度升高。结果表明,金属污染可能会改变生活在金属污染地区的小型雀形目动物的早期细菌群落。
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引用次数: 0
Selected rhizobacteria strains improved the tolerance of Vicia faba plants to microcystins contaminated irrigation water and reduced human health risk 经筛选的根瘤菌菌株提高了蚕豆植株对微囊藻毒素污染灌溉水的耐受性,降低了人类健康风险。
IF 5.8 3区 环境科学与生态学 0 ENVIRONMENTAL SCIENCES Pub Date : 2025-11-21 DOI: 10.1007/s11356-025-37185-7
Nadia Elidrissi El Yallouli, El Mahdi Redouane, Richard Mugani, Lahcen Ouchari, Mariana Girão, Maria Fátima Carvalho, Alexandre Campos, Vitor Vasconcelos, Brahim Oudra, Majida Lahrouni, John Poté

In Morocco as well as in many countries located in semi-arid areas, irrigation with water from lake-reservoirs is a common agricultural practice and an important tool for farmers to improve crop yields. However, this kind of water can contain toxic bloom-forming cyanobacteria, and its use as a source for irrigation water can enable a transfer of cyanobacterial toxins (microcystins) into crop plant. When microcystins are accumulated in crop plants, they pose serious human health risk. The aim of this study is to explore the potential of selected rhizobacteria strains in inoculation with Vicia faba plants to mitigate microcystins-induced phytotoxicity and health risks. Irrigation with water containing 200 µg L−1 microcystins reduced plant growth, photosynthetic efficiency, and nitrogen assimilation. Inoculation with selected rhizobacteria strains alleviated these effects, enhancing root biomass, stomatal conductance, chlorophyll content, leaf quantum yield, and nitrogen content and slightly increasing GS activity. Among tested strains, Achromobacter marplatensis showed the strongest protection, reducing microcystin accumulation by approximately 36% compared to uninoculated plants. Estimated daily intake values derived from residual microcystins remained below World Health Organization safety thresholds, indicating a lowered potential risk. These findings demonstrate that soil-based inoculation with targeted rhizosphere bacteria can protect plants from microcystin-induced damage, providing a strain-specific, sustainable bioremediation strategy to maintain crop productivity and food safety in regions exposed to microcystin-contaminated irrigation water.

在摩洛哥以及位于半干旱地区的许多国家,用湖泊水库的水灌溉是一种普遍的农业做法,也是农民提高作物产量的重要工具。然而,这种水可能含有有毒的形成水华的蓝藻,它作为灌溉用水的来源可以使蓝藻毒素(微囊藻毒素)转移到作物植物中。当微囊藻毒素在作物植物中积累时,它们对人体健康构成严重威胁。本研究的目的是探讨选定的根瘤菌菌株接种蚕豆植物以减轻微囊藻毒素引起的植物毒性和健康风险的潜力。用含有200µg L-1微囊藻毒素的水灌溉会降低植物的生长、光合效率和氮同化。接种特定的根菌可以缓解这些影响,提高根生物量、气孔导度、叶绿素含量、叶片量子产率和氮含量,并略微提高GS活性。在所测试的菌株中,马氏无色杆菌表现出最强的保护作用,与未接种的植株相比,其微囊藻毒素积累减少了约36%。残留微囊藻毒素的估计每日摄入量仍低于世界卫生组织的安全阈值,表明潜在风险较低。这些发现表明,在土壤中接种目标根际细菌可以保护植物免受微囊藻毒素诱导的损害,为微囊藻毒素污染灌溉水暴露地区维持作物生产力和食品安全提供了一种菌株特异性、可持续的生物修复策略。
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引用次数: 0
Using explainable artificial intelligence for mapping health vulnerability: Interaction-based analysis of multiple sources of data in Latin America 使用可解释的人工智能绘制健康脆弱性:拉丁美洲多种数据来源的基于交互的分析。
IF 5.8 3区 环境科学与生态学 0 ENVIRONMENTAL SCIENCES Pub Date : 2025-11-21 DOI: 10.1007/s11356-025-37051-6
Susana Alexandra Arias Tapia, Andrea Suárez López, Janio Jadán-Guerrero

Even as there are extensive genetic linkages across Latin America, local health risk is influenced by a host of interdependent factors that include (a) ethnic heterogeneity, (b) geographical isolation, and (c) disproportionate access to healthcare. The article presents a new explainable artificial intelligence (XAI) model for mapping and interpreting health vulnerability, combining several open-access datasets, such as disease prevalence, medical supply, and genetic ancestry profiles. We introduce a compound Interaction Index, as the product of ethnic diversity (E), inverted medical access (1 − M), and altitude (A), to quantify compounded structural and biological risk factors. Applying supervised learning models (F1 = 0.596 for SVM, F1 = 0.571 for gradient boosting, and logistic regression), in combination with unsupervised clustering and interpretable classification trees, we detect the high-risk regions with high diversity, low access, and mid-to-high altitude. This transparent and scalable methodology for equitable public health planning illuminates such ‘clusters of vulnerability’ which might remain hidden amid aggregate data.

尽管拉丁美洲各地存在广泛的遗传联系,但当地的健康风险受到许多相互依存因素的影响,这些因素包括(a)种族异质性,(b)地理隔离,以及(c)获得医疗保健的机会不成比例。本文提出了一个新的可解释的人工智能(XAI)模型,用于绘制和解释健康脆弱性,结合几个开放获取的数据集,如疾病流行、医疗供应和遗传血统概况。我们引入了一个复合相互作用指数,作为种族多样性(E),反向医疗可及性(1 - M)和海拔(a)的乘积,量化复合结构和生物风险因素。应用监督学习模型(支持向量机F1 = 0.596,梯度增强F1 = 0.571,逻辑回归),结合无监督聚类和可解释分类树,检测高多样性、低可达性和中高海拔的高风险区域。这种透明和可扩展的公平公共卫生规划方法揭示了可能隐藏在汇总数据中的“脆弱性集群”。
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引用次数: 0
Unraveling the molecular pathways linking polystyrene exposure and depression 揭示聚苯乙烯暴露与抑郁症之间的分子途径。
IF 5.8 3区 环境科学与生态学 0 ENVIRONMENTAL SCIENCES Pub Date : 2025-11-21 DOI: 10.1007/s11356-025-37184-8
Meesala Krishna Murthy

Polystyrene micro- and nanoplastics have become major neurotoxicants in the environment with respect to mental health in the case of depression. This review summarizes the existing experimental, epidemiological, and mechanistic data pertaining to exposure to polystyrene micro- and nanoplastics and their relationship with neurobehavioral imbalances. The particles may enter the brain by passing through the blood–brain barrier and accumulate in neural tissues, leading to in turn cause neuronal imbalance via oxidative stress, neuroinflammation, mitochondrial dysfunction, and synaptic and neurotransmitter maladaptation. These processes resemble the neurobiological foundation of major depressive disorders, such as serotonergic, dopaminergic, and glutamatergic dysfunction; dysregulation of the hypothalamic-pituitary-adrenocortical axis; and impairment of neuroplasticity. Despite limited human research, biomonitoring has shown the presence of polystyrene micro- and nanoplastics in the blood, placenta, and feces, leading to widespread and chronic exposure to these plastics. There is a risk that the most vulnerable groups (children, pregnant women, and industrial workers) may be affected disproportionately. To address these risks, human-relevant models and omics approaches, as well as longitudinal cohort studies, must be incorporated into future studies with regulatory frameworks to reduce exposure and safeguard mental health.

聚苯乙烯微塑料和纳米塑料已成为环境中影响抑郁症患者心理健康的主要神经毒物。本文综述了有关聚苯乙烯微塑料和纳米塑料暴露及其与神经行为失衡关系的现有实验、流行病学和机理数据。这些颗粒可能通过血脑屏障进入大脑并在神经组织中积累,进而通过氧化应激、神经炎症、线粒体功能障碍以及突触和神经递质适应不良导致神经元失衡。这些过程类似于重度抑郁症的神经生物学基础,如血清素能、多巴胺能和谷氨酸能功能障碍;下丘脑-垂体-肾上腺皮质轴的失调;神经可塑性受损。尽管人体研究有限,但生物监测显示,血液、胎盘和粪便中存在聚苯乙烯微塑料和纳米塑料,导致广泛和长期接触这些塑料。最脆弱的群体(儿童、孕妇和产业工人)可能受到不成比例的影响。为了解决这些风险,必须将与人类相关的模型和组学方法以及纵向队列研究纳入未来的研究,并制定监管框架,以减少接触并保障精神健康。
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Environmental Science and Pollution Research
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