{"title":"Assessing Nonculprit Coronary-Artery Lesions in STEMI.","authors":"William F Fearon","doi":"10.1056/nejme2517834","DOIUrl":"https://doi.org/10.1056/nejme2517834","url":null,"abstract":"","PeriodicalId":54725,"journal":{"name":"New England Journal of Medicine","volume":"43 1","pages":"1021-1022"},"PeriodicalIF":158.5,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147350594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Strategies to Reinvigorate the Bedside Clinical Encounter. Reply.","authors":"Brian T Garibaldi, Stephen W Russell","doi":"10.1056/NEJMc2600934","DOIUrl":"https://doi.org/10.1056/NEJMc2600934","url":null,"abstract":"","PeriodicalId":54725,"journal":{"name":"New England Journal of Medicine","volume":"394 10","pages":"1039-1040"},"PeriodicalIF":78.5,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-05Epub Date: 2026-02-28DOI: 10.1056/NEJMp2415615
Ruqaiijah Yearby, Marcella Alsan
{"title":"Private Equity's Transformation of American Medicine - Implications for Health Equity.","authors":"Ruqaiijah Yearby, Marcella Alsan","doi":"10.1056/NEJMp2415615","DOIUrl":"10.1056/NEJMp2415615","url":null,"abstract":"","PeriodicalId":54725,"journal":{"name":"New England Journal of Medicine","volume":" ","pages":"937-940"},"PeriodicalIF":78.5,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147328199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-05Epub Date: 2026-02-28DOI: 10.1056/NEJMicm2503296
Hadi Jaradeh, Alejandro P Comellas
{"title":"Expiratory Central Airway Collapse.","authors":"Hadi Jaradeh, Alejandro P Comellas","doi":"10.1056/NEJMicm2503296","DOIUrl":"10.1056/NEJMicm2503296","url":null,"abstract":"","PeriodicalId":54725,"journal":{"name":"New England Journal of Medicine","volume":" ","pages":"1010"},"PeriodicalIF":78.5,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147328207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Salma M A Gayed, Michael P Motley, Julia M Carlson, Kiersten S Lupu, Nikolaos Mavrogiorgos
{"title":"The Eyes Have It.","authors":"Salma M A Gayed, Michael P Motley, Julia M Carlson, Kiersten S Lupu, Nikolaos Mavrogiorgos","doi":"10.1056/NEJMcps2508044","DOIUrl":"https://doi.org/10.1056/NEJMcps2508044","url":null,"abstract":"","PeriodicalId":54725,"journal":{"name":"New England Journal of Medicine","volume":"394 10","pages":"1011-1017"},"PeriodicalIF":78.5,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christos P Kotanidis, Paul K Whelton, Clinton B Wright
{"title":"Blood-Pressure Targets in Hypertension Management.","authors":"Christos P Kotanidis, Paul K Whelton, Clinton B Wright","doi":"10.1056/NEJMclde2505268","DOIUrl":"https://doi.org/10.1056/NEJMclde2505268","url":null,"abstract":"","PeriodicalId":54725,"journal":{"name":"New England Journal of Medicine","volume":"394 10","pages":"1026-1029"},"PeriodicalIF":78.5,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aspirin after PCI in Acute Coronary Syndromes.","authors":"Sofie Chin Ha Chan","doi":"10.1056/NEJMc2518964","DOIUrl":"https://doi.org/10.1056/NEJMc2518964","url":null,"abstract":"","PeriodicalId":54725,"journal":{"name":"New England Journal of Medicine","volume":"394 10","pages":"1036"},"PeriodicalIF":78.5,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Radiotherapy is a key foundation of oncologic treatment that is used across the spectrum of cancer indications. Advances in imaging, treatment planning, and dose delivery have led to increasingly conformal and even ablative treatments, which have resulted in improved tumor control with no increase in the risk of side effects (or with a decrease in risk) as compared with previous treatments. These advances have facilitated the combined use of radiotherapy with efficacious systemic therapies, including targeted treatments and immunotherapies. Radiation-induced changes in normal tissue occur as a result of stem-cell senescence, inflammation, vascular changes, fibroblast activation, and loss of parenchymal cells. Research into the biologic underpinnings of radiation-induced changes in normal tissue, biomarkers of side effects of various irradiation regimens, and new treatment methods offers great promise for further increasing the efficacy of radiotherapy and improving the side-effect profile through personalized approaches.
{"title":"Effects of Radiotherapy in Normal Tissue.","authors":"Deborah E Citrin,Robert D Timmerman","doi":"10.1056/nejmra2506017","DOIUrl":"https://doi.org/10.1056/nejmra2506017","url":null,"abstract":"Radiotherapy is a key foundation of oncologic treatment that is used across the spectrum of cancer indications. Advances in imaging, treatment planning, and dose delivery have led to increasingly conformal and even ablative treatments, which have resulted in improved tumor control with no increase in the risk of side effects (or with a decrease in risk) as compared with previous treatments. These advances have facilitated the combined use of radiotherapy with efficacious systemic therapies, including targeted treatments and immunotherapies. Radiation-induced changes in normal tissue occur as a result of stem-cell senescence, inflammation, vascular changes, fibroblast activation, and loss of parenchymal cells. Research into the biologic underpinnings of radiation-induced changes in normal tissue, biomarkers of side effects of various irradiation regimens, and new treatment methods offers great promise for further increasing the efficacy of radiotherapy and improving the side-effect profile through personalized approaches.","PeriodicalId":54725,"journal":{"name":"New England Journal of Medicine","volume":"16 1","pages":"996-1009"},"PeriodicalIF":158.5,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147350593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Finerenone for Diabetic Kidney Disease in Type 1 Diabetes - A Fine Answer?","authors":"Aleksandra Kukla,Marie C Hogan","doi":"10.1056/nejme2600575","DOIUrl":"https://doi.org/10.1056/nejme2600575","url":null,"abstract":"","PeriodicalId":54725,"journal":{"name":"New England Journal of Medicine","volume":"1 1","pages":"1019-1020"},"PeriodicalIF":158.5,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147350596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-05Epub Date: 2026-02-28DOI: 10.1056/NEJMp2514612
Alexandra Alvarez, Caroline E Sloan, Peter A Ubel
{"title":"Debt by Design - Navigating the Hazards of Medical Credit Cards.","authors":"Alexandra Alvarez, Caroline E Sloan, Peter A Ubel","doi":"10.1056/NEJMp2514612","DOIUrl":"10.1056/NEJMp2514612","url":null,"abstract":"","PeriodicalId":54725,"journal":{"name":"New England Journal of Medicine","volume":" ","pages":"943-945"},"PeriodicalIF":78.5,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147328229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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