Cognitive challenges are common and often impede performing everyday tasks after acquired brain injury. Occupational therapists working with client groups with cognitive impairments seek evidence-based, occupation-based interventions to help individuals achieve independence in everyday activities. The aim of the study was to evaluate the effectiveness of the Perceive, Recall, Plan and Perform (PRPP) Intervention in increasing task mastery for individuals with cognitive challenges post-brain injury. This study is part of a systematic replication series and employed a multiple baseline design with intersubject replication across four participants with brain injury in a local inpatient rehabilitation context. Occupational therapists conducted nine PRPP Intervention sessions over three weeks during everyday tasks and collected data using the PRPP Assessment during baseline, intervention, post-intervention, and follow-up phases. Results were analyzed using systematic visual inspection, Tau-U, and descriptive methods. Different analytical methods yielded divergent results, with limited evidence of an immediate change. However, all four participants demonstrated improved task mastery after the intervention was completed, three with clinically significant improvements. The PRPP Intervention provides occupational therapists with a standardized and occupation-based approach to cognitive rehabilitation for individuals following brain injury. This study contributes to the existing knowledge base on the PRPP Intervention.Trial registration: NCT05148247.
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