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Measurement of cross-language and cross-domain generalization following semantic feature-based anomia treatment in bilingual aphasia. 基于语义特征的失语症治疗对双语失语症患者跨语言和跨领域泛化的影响。
IF 1.9 3区 心理学 Q4 NEUROSCIENCES Pub Date : 2026-04-01 Epub Date: 2025-06-26 DOI: 10.1080/09602011.2025.2522196
Marissa Russell-Meill, Erin Carpenter, Manuel J Marte, Michael Scimeca, Claudia Peñaloza, Swathi Kiran

Semantic feature-based treatment (SFT), which engages the semantic network by repeatedly targeting retrieval of conceptual features to improve lexical-semantic access, has shown promise for facilitating generalization in aphasia rehabilitation. However, its capacity to drive broad improvement across cognitive-linguistic domains in bilinguals with aphasia (BWA) remains unclear. This study examined generalization effects (i.e., direct transfer, near transfer, and far transfer) following SFT in 48 Spanish-English BWA who took part in a randomized controlled trial. Participants received 40 h of SFT targeting word retrieval, with generalization assessed across three domains: naming of untrained items (direct transfer), semantic processing (near transfer), as well as global language ability and nonverbal abstract reasoning (far transfer). Results showed (i) robust improvements for trained and untrained naming targets, demonstrating direct transfer, (ii) near transfer effects for select semantic processing tasks, and (iii) far transfer limited to overall language function, with no gains in domain-general cognition. Notably, treatment benefits extended across languages, demonstrating cross-language generalization to multiple domains of language processing. Findings highlight SFT's capacity to drive comprehensive language recovery in BWA, revealing broad generalization effects across languages and linguistic domains. Such effects underscore the importance of systematically examining generalization patterns to optimize rehabilitation outcomes.Trial registration: ClinicalTrials.gov identifier: NCT02916524.

基于语义特征的治疗(Semantic feature based treatment,简称SFT)是一种利用语义网络反复定位概念特征的检索来改善词汇-语义获取的方法,在失语康复中具有促进泛化的前景。然而,它在双语失语症(BWA)患者认知语言领域的广泛改善能力尚不清楚。本研究采用随机对照试验对48例西班牙-英语BWA进行了SFT后的泛化效应(即直接迁移、近迁移和远迁移)的研究。参与者接受了40小时的以单词检索为目标的SFT,并评估了三个领域的泛化:未训练项目的命名(直接迁移),语义处理(近迁移),以及全局语言能力和非语言抽象推理(远迁移)。结果显示:(i)训练和未训练的命名目标有显著改善,显示直接迁移;(ii)选择语义处理任务的近迁移效果;(iii)远迁移仅限于整体语言功能,在领域一般认知方面没有增益。值得注意的是,治疗的好处扩展到不同的语言,表明跨语言泛化到语言处理的多个领域。研究结果强调了SFT在BWA中推动全面语言恢复的能力,揭示了跨语言和语言领域的广泛泛化效应。这些影响强调了系统地检查泛化模式以优化康复结果的重要性。试验注册:ClinicalTrials.gov标识符:NCT02916524。
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引用次数: 0
Self-reported reading difficulties and rehabilitation goals in individuals with homonymous visual field defects. 同名视野缺损患者自述阅读困难与康复目标。
IF 1.9 3区 心理学 Q4 NEUROSCIENCES Pub Date : 2026-04-01 Epub Date: 2025-06-23 DOI: 10.1080/09602011.2025.2516563
Sarah Tol, Gera A de Haan, Joost Heutink

Homonymous Visual Field Defects (HVFDs) often cause reading difficulties. Self-reported reading difficulties and reading intervention goals remain however understudied. This study explores the prevalence of self-reported reading difficulties in 24 individuals with HVFDs, compared to their pre-HVFD experiences and to 160 matched controls. A comparison between left- and right-sided HVFDs is also included. Additionally, we examined which reading skills and reading objects individuals with HVFDs wished to improve. Using the novel Hemianopia Reading Questionnaire, we found that individuals with HVFDs reported poorer reading efficacy, poorer reading skills and poorer reading of different objects compared to pre-HVFD levels and control participants. However, love for and the importance of reading appear unaffected by the HVFD. Reading speed and orientation were the most affected skills after HVFD. Individuals with right-HVFDs reported lower reading speed compared to individuals with left-HVFDs. Reading books was the most desired goal for improvement, yet reading books was also the most abandoned object after HVFD. Overall, the current study indicates the importance of reading in individuals with HVFD and highlights that self-reported reading difficulties occur in a broad range of difficulties related to efficacy, skills and reading objects and should be incorporated in future effect measures of HVFD-intervention studies.

同义视野缺陷(hvfd)经常导致阅读困难。然而,自我报告的阅读困难和阅读干预目标仍未得到充分研究。本研究探讨了24名hvfd患者自我报告的阅读困难的流行程度,并与他们在hvfd前的经历和160名匹配的对照进行了比较。左、右侧hvfd的比较也包括在内。此外,我们还研究了hvfd患者希望提高哪些阅读技能和阅读对象。使用新的偏盲阅读问卷,我们发现,与未患偏盲的受试者和对照组相比,患有偏盲的受试者的阅读效率、阅读技能和对不同物体的阅读能力都较差。然而,对阅读的热爱和重要性似乎不受HVFD的影响。阅读速度和方向是HVFD后受影响最大的技能。与左心室畸形患者相比,右心室畸形患者的阅读速度较慢。阅读书籍是人们最希望改善的目标,但阅读书籍也是在HVFD之后最被抛弃的对象。总的来说,目前的研究表明了阅读对HVFD患者的重要性,并强调了自我报告的阅读困难发生在与疗效、技能和阅读对象相关的广泛困难中,应纳入HVFD干预研究的未来效果测量。
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引用次数: 0
Exploring the meaning of life (MoL) after acquired brain injury (ABI) in Costa Rica. 探索哥斯达黎加获得性脑损伤(ABI)后的生命意义(MoL)。
IF 1.9 3区 心理学 Q4 NEUROSCIENCES Pub Date : 2026-04-01 Epub Date: 2025-06-20 DOI: 10.1080/09602011.2025.2520494
Mónica Salazar-Villanea, Javeth Calvo-Molina

Primary objective: This study aimed to explore the process of MoL-Resignification following ABI in a Costa Rican sample.

Research design: A cross-sectional, exploratory mixed-method approach.

Methods and procedures: Qualitative narratives about the MoL-Resignification were collected and supported with quantitative data using instruments like the Mental and Physical Health Adapted Scale (MPHAS), Brief Resilient Coping Scale (BRCS), UCLA Loneliness Scale Revised (UCLALS-R), and New Me Scale (NMS).

Main outcomes: Four dimensions of MoL-Resignification after ABI were identified: Individual, Social, Global, and Spiritual. Narratives regarding the Individual MoL ranged from coping with the limitations imposed by ABI to adopting new values and senses of identity. Social MoL emphasized the importance of family support, while Global MoL centred on adopting a present-focused perspective. The Spiritual MoL highlighted the role of faith and religious beliefs in helping individuals navigate their lives after ABI. Resignification processes were associated with greater life satisfaction post-ABI (NMS), lower psychological and physical burdens (MPHAS), reduced loneliness (UCLALS-R), and more effective coping strategies (BRCS).

Conclusions: MoL-Resignification and Identity change after ABI, demonstrates the importance of family and spiritual beliefs in coping within the context of Costa Rican culture. These factors should be addressed in future research and rehabilitation efforts.

主要目的:本研究旨在探讨在哥斯达黎加样本ABI后mol - reignification的过程。研究设计:横断面、探索性混合方法。方法和步骤:采用心理和身体健康适应量表(MPHAS)、简短弹性应对量表(BRCS)、UCLA孤独量表修订版(UCLALS-R)和新自我量表(NMS)等工具收集moll - resignification的定性叙述,并采用定量数据进行支持。主要结果:确定了ABI后mol - resigntion的四个维度:个人,社会,全球和精神。关于个体MoL的叙述范围从应对ABI施加的限制到采用新的价值观和认同感。社会MoL强调家庭支持的重要性,而全球MoL侧重于采用以现在为中心的观点。精神MoL强调了信仰和宗教信仰在帮助个人在ABI后的生活中所起的作用。辞职过程与abi后更高的生活满意度(NMS)、更低的心理和身体负担(MPHAS)、更少的孤独感(UCLALS-R)和更有效的应对策略(BRCS)相关。结论:ABI后的moll - resignification和身份变化表明了家庭和精神信仰在哥斯达黎加文化背景下应对的重要性。这些因素应在今后的研究和康复工作中加以解决。
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引用次数: 0
Constructing the conditions for wellbeing: A qualitative evaluation of group-based ecotherapy for adults living with acquired brain injury. 构建健康条件:对成年后天性脑损伤患者群体生态疗法的定性评价。
IF 1.9 3区 心理学 Q4 NEUROSCIENCES Pub Date : 2026-04-01 Epub Date: 2025-06-13 DOI: 10.1080/09602011.2025.2516560
Katie Gibbs, Zoe Fisher, Kate Denner, Andrew H Kemp

Ecotherapy interventions which promote meaningful engagement with the natural world provide unique wellbeing opportunities for individuals with psychosocial difficulties who may struggle to access nature, while also benefiting the local community and environment. We hereby unpack the experiences of 41 adults living with the psychosocial sequelae of acquired brain injury following their engagement in a group-based eight-to-ten-week sustainable construction intervention delivered in partnership with a local social enterprise called "Down to Earth". Using reflexive thematic analysis, insights from seven focus groups emphasize the importance of (1) Broadening skills and building for the future in supporting movement towards an engaged and meaningful life; (2) Shared experiences with similar others in facilitating belonging in group memberships; (3) Self-acceptance and identity in cultivating resources for personal growth, and (4) Connecting and contributing, which is critical for community and planetary wellbeing. Opportunities for enhancing local clinical practice are captured within a domain summary theme, and broader implications for "inner" (personal and relational capacities) and global sustainable development are discussed.

生态疗法干预措施促进了与自然世界的有意义的接触,为那些可能难以接近自然的心理社会困难的个人提供了独特的健康机会,同时也使当地社区和环境受益。在此,我们对41名患有后发性脑损伤后遗症的成年人的经历进行了分析,他们参与了一个以团体为基础的为期8至10周的可持续建设干预,该干预是与当地一家名为“脚踏实地”的社会企业合作提供的。使用反身性主题分析,来自七个焦点小组的见解强调了以下几点的重要性:(1)拓宽技能并为未来建设提供支持,以实现投入和有意义的生活;(2)与相似的人分享经验,以促进群体成员的归属感;(3)在培养个人成长资源方面的自我接纳和认同;(4)联系和贡献,这对社区和地球的福祉至关重要。在领域总结主题中捕获了加强当地临床实践的机会,并讨论了对“内部”(个人和关系能力)和全球可持续发展的更广泛影响。
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引用次数: 0
Music listening for fatigue after acquired brain injury: A scoping review project with patient, carer and public involvement (PCPI) data. 获得性脑损伤后的疲劳听音乐:一个病人、护理者和公众参与(PCPI)数据的范围审查项目。
IF 1.9 3区 心理学 Q4 NEUROSCIENCES Pub Date : 2026-04-01 Epub Date: 2025-10-03 DOI: 10.1080/09602011.2025.2526655
Alexander Street, Jonathan Pool, Sheryl Parke, Louise Gilbert, Parnian Motaghilotf, Jessica Blake, Nina Wollersberger

Fifty percent of Acquired Brain Injury (ABI) survivors experience fatigue. Symptom management in post-acute rehabilitation, where rehabilitation adherence is essential, is lacking. Research suggests that music listening interventions could help by addressing related symptoms including pain, mood and arousal. Our objective was to explore how music listening has been used for post-ABI fatigue and whether findings, together with interview data from a post-acute ward, could inform on its use for this purpose. Synthesized data included: intervention characteristics, study design and outcomes. Joanna Briggs Institute guidelines and PRISMA checklist were applied. Nine-hundred and eighty-seven abstracts and 29 full texts were screened, with thirteen papers on nine studies included. Fatigue was reported only as a secondary outcome and not defined by type. Associated outcomes included: increased self-reported stamina, vitality, arousal, sleep and relaxation, better mood and pain management, verbal memory and attention. Interview data (patients: n = 6; staff: n = 4; caregivers: n = 2) suggest the need for time allocation for music listening, help with equipment setup, and trialling to determine duration and frequency. Future studies should screen for fatigue type and symptoms and establish with participants whether music interventions might be beneficial for energizing or relaxing, and if complimentary to cited strategies including exercise or meditation.

50%的获得性脑损伤(ABI)幸存者会感到疲劳。急性康复后的症状管理缺乏,而康复依从性是必不可少的。研究表明,听音乐干预可以帮助解决相关症状,包括疼痛、情绪和兴奋。我们的目的是探讨听音乐是如何用于abi后疲劳的,以及研究结果,以及来自急性期后病房的访谈数据,是否可以为其用于这一目的提供信息。综合资料包括:干预特征、研究设计和结果。采用乔安娜布里格斯研究所指南和PRISMA检查表。筛选了987份摘要和29份全文,其中包括9项研究的13篇论文。疲劳仅作为次要结果报告,未按类型定义。相关结果包括:增强自我报告的耐力、活力、觉醒、睡眠和放松,更好的情绪和疼痛管理,言语记忆和注意力。访谈数据(患者:n = 6;工作人员:n = 4;护理人员:n = 2)表明,需要为音乐聆听分配时间,帮助设置设备,并尝试确定持续时间和频率。未来的研究应该筛选疲劳类型和症状,并与参与者一起确定音乐干预是否有利于激活或放松,以及是否与所引用的策略(包括运动或冥想)互补。
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引用次数: 0
Validation and clinical applicability of the Screening Visual Complaints questionnaire-acquired brain injury (SVCq-abi) in individuals with acquired brain injury. 获得性脑损伤患者视力疾患筛查问卷(SVCq-abi)的有效性及临床适用性
IF 1.9 3区 心理学 Q4 NEUROSCIENCES Pub Date : 2026-04-01 Epub Date: 2025-07-16 DOI: 10.1080/09602011.2025.2526648
Vera Linde Dol, Arlette J van Sorge, Anselm B M Fuermaier, Wietske Rienstra, Radha Rambaran Mishre, Eline M E Will, Joost Heutink

The 23-item Screening Visual Complaints questionnaire-acquired brain injury (SVCq-abi) was constructed to assess visual complaints in individuals with acquired brain injury (ABI). This cross-sectional study determines the validity and clinical applicability of the SVCq-abi in an ABI sample. The SVCq-abi was administered to 156 individuals with ABI (mean [SD], 58 [13] years, 36% female) following a neurorehabilitation programme (65% inpatient, 35% outpatient). Confirmatory factor analysis (CFA) was performed to determine the fit of a 5-factor model, and scale reliability was examined. Additionally, we assessed the distribution of responses on the SVCq-abi and the effect of key clinical variables on SVCq-abi subscale scores. CFA confirmed a 5-factor model with good fit statistics, except for the Standardized Root Mean-square Residual. Scale reliability ranged from weak to good. Most individuals (78%) reported at least one visual complaint. Outpatients reported more luminance-related and ocular discomfort complaints than inpatients. No significant effect was observed on subscale scores based on administration method, history of ophthalmic disease, time since ABI diagnosis, and age. CFA determined a 5-factor structure of the SVCq-abi, with sufficient scale. Individuals with ABI experienced a range of visual complaints. The SVCq-abi showed broad clinical applicability and may be a valuable tool for clinical practice.

为评估获得性脑损伤(ABI)患者的视觉主诉,设计了包含23个条目的《获得性脑损伤视力主诉筛查问卷》(SVCq-abi)。本横断面研究确定了SVCq-abi在ABI样本中的有效性和临床适用性。在神经康复计划(65%住院,35%门诊)后,对156名ABI患者(平均[SD], 58岁,36%女性)实施SVCq-abi。采用验证性因子分析(CFA)确定5因素模型的拟合,并检验量表信度。此外,我们评估了SVCq-abi的反应分布以及关键临床变量对SVCq-abi亚量表得分的影响。除了标准化均方根残差外,CFA证实了一个具有良好拟合统计量的5因素模型。量表的可靠性从弱到好。大多数人(78%)报告至少有一种视觉不适。与住院患者相比,门诊患者报告了更多与亮度相关的不适和眼部不适。基于给药方式、眼病史、ABI诊断时间和年龄的亚量表评分未观察到显著影响。CFA确定了SVCq-abi的5因子结构,具有足够的量表。ABI患者有一系列的视觉不适。SVCq-abi具有广泛的临床适用性,可能是临床实践中有价值的工具。
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引用次数: 0
A randomized trial showing mnemonic strategy training increases memory, brain activation, and functional connectivity more than vanishing cue training in cognitively intact older adults. 一项随机试验显示,在认知完整的老年人中,记忆策略训练比消失线索训练更能提高记忆力、大脑激活和功能连接。
IF 1.9 3区 心理学 Q4 NEUROSCIENCES Pub Date : 2026-04-01 Epub Date: 2025-10-01 DOI: 10.1080/09602011.2025.2525349
Benjamin M Hampstead, Alexandru D Iordan, Robert Ploutz-Snyder, Bidisha Ghosh, Ashley Harrie, Anthony Y Stringer, K Sathian

Objectives: This single-blind, parallel groups, randomized controlled trial examined whether (1) mnemonic strategy training (MST) improved memory for face-name associations relative to vanishing cue training (VCT) and (2) the interventions modulated blood oxygen level dependent (BOLD) signal in a training-specific manner.

Methods: We randomized 30 cognitively intact older adults to either MST or VCT (1:1 basis). Memory for face-name associations (primary outcome) was evaluated at baseline and post-training using functional magnetic resonance imaging (fMRI) and again at 1-month follow-up (memory test only). During training sessions, MST participants applied a 3-step strategy while those receiving VCT recalled the targeted name across trials with letters subtracted (correct trials) or added (incorrect trials) as appropriate.

Results: There were no adverse events and excellent retention. The magnitude of memory test improvement was significantly greater after MST at both post-training and 1-month relative to VCT. The MST group also showed significantly greater BOLD signal changes in multiple brain regions as well as increased functional connectivity between networks relative to the VCT group.

Conclusions: MST is superior to VCT for enhancing long-term retention of face-name associations in cognitively intact older adults and appears to enhance use of lateral frontoparietal regions and networks involved in top-down processing.

目的:本单盲、平行组、随机对照试验研究了(1)相对于消失提示训练(VCT),助记策略训练(MST)是否改善了面孔-名字关联记忆;(2)干预是否以特定训练方式调节血氧水平依赖(BOLD)信号。方法:我们随机选择30名认知完整的老年人进行MST或VCT(1:1为基础)。使用功能磁共振成像(fMRI)在基线和训练后评估面孔-名字联想记忆(主要结果),并在1个月的随访中再次评估(仅记忆测试)。在训练过程中,MST参与者采用三步策略,而那些接受VCT的参与者则在不同的试验中适当地减去(正确的试验)或增加(错误的试验)字母来回忆目标名字。结果:无不良反应,保留性好。与VCT相比,MST在训练后和1个月的记忆测试改善幅度均显著增加。与VCT组相比,MST组在多个脑区也显示出明显更大的BOLD信号变化,以及网络之间功能连接的增加。结论:在认知完整的老年人中,MST在增强面孔-名字关联的长期保留方面优于VCT,并且似乎增强了参与自上而下加工的侧额顶叶区域和网络的使用。
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引用次数: 0
Development and psychometric validation of the hospital discharge readiness scale for post-operative brain tumour patients in Chinese adults. 中国成人脑肿瘤术后出院准备程度量表的编制及心理测量学验证。
IF 1.9 3区 心理学 Q4 NEUROSCIENCES Pub Date : 2026-04-01 Epub Date: 2025-07-03 DOI: 10.1080/09602011.2025.2523915
Longti Li, Rong Zhang, Na Wang, Xin Chen, Huiqin Zhong, Boxiong Gong, Jie Luo

The purpose of this study was to develop a specific instrument to assess the discharge readiness among Chinese adults following brain tumour surgery and evaluate its psychometric properties. The construction of this measurement tool from March 2022 to April 2024 comprised two stages: the development of the scale (Stage I) and a cross-sectional survey involving 413 post-operative brain tumour patients to test its psychometric properties (Stage II). The final scale had 24 items with 4 domains. The item-level content validity index ranged from 0.850 to 1.000, and the scale-level content validity index was 0.926. Exploratory factor analysis showed a four-factor structure of the 24-item scale, accounting for 63.319% of the variance. The structures of confirmatory factor analysis formed validated acceptable fit indices after modification, which further confirmed the fit of the scale to the model. The scale showed an acceptable concurrent validity when compared with the RHDS (r = 0.456-0.875, p < 0.001). The Cronbach's α and split-half reliability of the total scale was 0.894 and 0.813, respectively. The scale has good reliability and validity and can be used to assess the discharge readiness of Chinese adults following brain tumour surgery.

本研究的目的是开发一种专门的工具来评估中国成人脑肿瘤手术后的出院准备情况,并评估其心理测量学特征。从2022年3月到2024年4月,该测量工具的构建包括两个阶段:量表的开发(第一阶段)和涉及413名术后脑肿瘤患者的横断面调查,以测试其心理测量特性(第二阶段)。最终量表有24个题项,共4个域。项目层面的内容效度指数为0.850 ~ 1.000,量表层面的内容效度指数为0.926。探索性因子分析显示,24项量表呈四因子结构,占方差的63.319%。修正后的验证性因子分析结构形成了有效的可接受拟合指标,进一步证实了量表与模型的拟合性。与RHDS量表比较,该量表具有可接受的并发效度(r = 0.456 ~ 0.875),总量表的p α和分半信度分别为0.894和0.813。该量表具有良好的信度和效度,可用于评估我国成人脑肿瘤手术后的出院准备情况。
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引用次数: 0
Psychoeducational interventions for patients with Long COVID and neuropsychological difficulties: A qualitative process evaluation of the COVCOG clinical trial. 长COVID合并神经心理困难患者的心理教育干预:COVCOG临床试验的定性过程评价
IF 1.9 3区 心理学 Q4 NEUROSCIENCES Pub Date : 2026-03-06 DOI: 10.1080/09602011.2026.2640067
Maxime Morsa, Lorène Dothée, Carmen Cabello, Alexia Lesoinne, Fabienne Collette, Sylvie Willems

Between 2022 and 2024, the COVCOG randomized controlled trial evaluated two psychoeducation interventions for people living with Long COVID: one addressing cognitive difficulties and the other affective difficulties. While the results showed small to moderate improvements in both groups, we still lack information on the individual and contextual mechanisms that facilitated or hindered the benefits of the intervention. Our research aimed to understand how, under what circumstances, and for whom the intervention generates changes. A qualitative process evaluation was conducted with patients and clinicians involved in COVCOG. Semi-structured individual interviews were conducted and analysed through reflexive thematic analysis. Sixteen patients and ten clinicians participated. Five themes were developed, helping to better understand the conditions for intervention success: Being recognized as a person with Long COVID, Learning to manage Long COVID on a daily basis, Changing as a person, Considering life after the intervention, and Adapting the clinical protocol. Our findings highlight the importance of both institutional and interpersonal recognition as a foundational mechanism for engagement and perceived effectiveness. Psychoeducation for people living with Long COVID should be designed as part of a broader, adaptive, and evolving care pathway, by supporting patients in navigating its biographical and functional consequences over time.

2022年至2024年期间,COVCOG随机对照试验评估了针对长冠肺炎患者的两种心理教育干预措施:一种针对认知困难,另一种针对情感困难。虽然结果显示两组都有小到中等程度的改善,但我们仍然缺乏促进或阻碍干预益处的个人和环境机制的信息。我们的研究旨在了解干预如何、在什么情况下以及对谁产生改变。对参与冬奥会组委会的患者和临床医生进行了定性过程评估。半结构化的个人访谈通过反身性主题分析进行分析。16名患者和10名临床医生参与。会议制定了五个主题,以帮助更好地理解干预成功的条件:被认可为长冠状病毒患者、学习日常管理长冠状病毒、作为一个人改变、考虑干预后的生活、适应临床方案。我们的研究结果强调了机构和人际认可作为参与和感知有效性的基本机制的重要性。长期COVID - 19患者的心理教育应作为更广泛、适应性和不断发展的护理途径的一部分,通过支持患者随着时间的推移应对其传记和功能后果。
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引用次数: 0
Changes in perceived cognitive functioning following a codesigned online group cognitive rehabilitation for prostate cancer survivors on androgen deprivation therapy: Series of single-case experimental designs. 前列腺癌幸存者接受雄激素剥夺治疗后认知功能的改变:一系列单例实验设计
IF 1.9 3区 心理学 Q4 NEUROSCIENCES Pub Date : 2026-03-04 DOI: 10.1080/09602011.2026.2637569
Lorna Pembroke, Kerry A Sherman, Haryana M Dhillon, Heather Francis, David Gillatt, Howard Gurney

Limited treatments exist for prostate cancer survivors (PCS) experiencing cancer-related cognitive impairment (CRCI). We aimed to investigate the feasibility, acceptability, and potential efficacy of an online group cognitive rehabilitation intervention for PCS on androgen deprivation therapy (ADT) experiencing CRCI. Eight adult, English-speaking PCS receiving ADT with perceived cognitive changes participated in a weekly, 2-hour, four-session intervention - "Promoting Cognitive Wellbeing in Prostate Cancer Survivors (ProCog)." A mixed methods approach was adopted using nonconcurrent, multiple baseline single-case experimental designs. Perceived cognitive functioning was measured weekly using the FACT-Cog Perceived Cognitive Impairments scale (PCI18). Brief objective cognitive testing, goal attainment scaling, and measures of depression, generalized anxiety, fatigue and self-efficacy were administered at four time-points. Feasibility and acceptability were assessed through attendance, homework adherence, and feedback. Most participants had locally advanced prostate cancer, were retired and lived in regional areas (mean age = 69 years). Most participants (5/8) demonstrated significant improvements in PCI18 despite no consistent changes on cognitive testing. All participants made progress towards goal attainment post-intervention. Clinically significant improvements were seen in levels of anxiety, depression, and fatigue, though changes in self-efficacy were variable. Session attendance and homework completion were at ≥97%. Larger-scaled studies are required to support ProCog's benefits.Trial registration: Prospectively registered on anzctr.org.au identifier: ACTRN12623000946617.

对于经历癌症相关认知障碍(CRCI)的前列腺癌幸存者(PCS),目前的治疗方法有限。我们的目的是探讨在线群体认知康复干预在雄激素剥夺治疗(ADT)经历CRCI的PCS的可行性、可接受性和潜在疗效。8名接受ADT治疗的成年、说英语、认知有改变的PCS参加了每周一次、2小时、4次的干预——“促进前列腺癌幸存者的认知健康(ProCog)”。采用非并发、多基线单例实验设计的混合方法。每周使用FACT-Cog感知认知障碍量表(PCI18)测量感知认知功能。在四个时间点进行简短的客观认知测试、目标实现量表以及抑郁、广泛性焦虑、疲劳和自我效能的测量。可行性和可接受性通过出勤、作业依从性和反馈来评估。大多数参与者患有局部晚期前列腺癌,退休并居住在地区(平均年龄= 69岁)。大多数参与者(5/8)表现出PCI18的显著改善,尽管在认知测试中没有一致的变化。所有参与者在干预后都朝着目标的实现取得了进展。焦虑、抑郁和疲劳水平均有临床意义上的改善,但自我效能感的变化不尽相同。会议出勤率和家庭作业完成率≥97%。需要更大规模的研究来支持ProCog的好处。试验注册:在anzctr.org.au上前瞻性注册,标识符:ACTRN12623000946617。
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引用次数: 0
期刊
Neuropsychological Rehabilitation
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