Pub Date : 2016-09-01DOI: 10.1016/j.gyobfe.2016.07.011
I. Capponi , P. Carquillat , Å. Premberg , F. Vendittelli , M.-J. Guittier
Objectives
For fathers, being present at a birth for the first time is not an insignificant event. Witnessing suffering can cause feelings of loneliness and powerlessness, which may be associated with postnatal problems such as depression. However, without a confirmed French-language tool concerning the experience of childbirth for fathers, we are limited in our ability to develop our understanding of their experiences and establish links between these experiences and their distress (anxiety, depression, etc.), or to develop appropriate methods of support. Our objective has been to translate and validate the Swedish “First-Time Father Questionnaire” with a French-speaking sample.
Methods
The tool was translated using a translation/backtranslation process (using two independent agencies, with a pre-test on 30 new fathers as well as exchanges with the Swedish authors). The French version was then tested with 154 new fathers at 1 month post-partum. Factorial analysis followed by multi-trait analysis and variance analyses were conducted, with subgroups contrasted according to the mode of delivery.
Results
The factorial structure is satisfactory, retaining 19 items and reproducing 54.12% of variance. Professional support, worry, and prenatal preparation constitute the 3 dimensions of this. Internal consistency, homogeneity, and the discriminating capacity of the questionnaire are good.
Conclusion
Validation of the questionnaire shows good metrological qualities. It can therefore be used in the perinatal field to evaluate the childbirth experience for first-time fathers.
{"title":"Vécu de l’accouchement par les pères : traduction et validation transculturelle du First-Time Father Questionnaire sur un échantillon francophone","authors":"I. Capponi , P. Carquillat , Å. Premberg , F. Vendittelli , M.-J. Guittier","doi":"10.1016/j.gyobfe.2016.07.011","DOIUrl":"10.1016/j.gyobfe.2016.07.011","url":null,"abstract":"<div><h3>Objectives</h3><p>For fathers, being present at a birth for the first time is not an insignificant event. Witnessing suffering can cause feelings of loneliness and powerlessness, which may be associated with postnatal problems such as depression. However, without a confirmed French-language tool concerning the experience of childbirth for fathers, we are limited in our ability to develop our understanding of their experiences and establish links between these experiences and their distress (anxiety, depression, etc.), or to develop appropriate methods of support. Our objective has been to translate and validate the Swedish “First-Time Father Questionnaire” with a French-speaking sample.</p></div><div><h3>Methods</h3><p>The tool was translated using a translation/backtranslation process (using two independent agencies, with a pre-test on 30 new fathers as well as exchanges with the Swedish authors). The French version was then tested with 154 new fathers at 1 month post-partum. Factorial analysis followed by multi-trait analysis and variance analyses were conducted, with subgroups contrasted according to the mode of delivery.</p></div><div><h3>Results</h3><p>The factorial structure is satisfactory, retaining 19 items and reproducing 54.12% of variance. Professional support, worry, and prenatal preparation constitute the 3 dimensions of this. Internal consistency, homogeneity, and the discriminating capacity of the questionnaire are good.</p></div><div><h3>Conclusion</h3><p>Validation of the questionnaire shows good metrological qualities. It can therefore be used in the perinatal field to evaluate the childbirth experience for first-time fathers.</p></div>","PeriodicalId":55077,"journal":{"name":"Gynecologie Obstetrique & Fertilite","volume":"44 9","pages":"Pages 480-486"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gyobfe.2016.07.011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10865816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-09-01DOI: 10.1016/j.gyobfe.2016.07.008
C. Racinet , J.-F. Peresse , G. Richalet , C. Corne , P. Ouellet
Objective
To apply a newly concept of neonatal eucapnic pH at birth [pH euc (n)] and compare its contribution towards conventional criteria of severe metabolic acidosis.
Methods
Analysis of a cohort of 5392 neonates from 2010 to 2014 in a level 1 maternity. clinical data (birth weight, gestational age, mode of delivery, APGAR score) were collected from archived files. Biological data were collected from umbilical cord blood, consisting of pH, PCO2, Base deficit, lactate. Eucapnic pH and eucapnic base deficit were calculated from pH and PCO2 with the Henderson-Hasselbalch equation applied in the Charles-Racinet diagram and/or with an Excel spreadsheet.
Results
Data set the prevalence of neonatal acidemia < 7.00 to 0.62 %. The current cohort shows 32 cases of severe neonatal metabolic acidosis according to ACOG-AAP (2014) criteria and 26/29 cases according to McLennan (2015) criteria, of which 80 % were born by cesarean section or instrumental delivery. In 55 % of cases, calculated eucapnic pH at birth did not confirm the severity of metabolic acidosis based on a threshold set at 7.11. Five cases were transferred in neonatalogy only on clinical considerations of poor neonatal adaptation but not on biological consideration (pH euc < 7.11 was equally distributed between transferred and non-transferred neonates, P = 0.76; the same distribution was observed with the pH, P = 0.20) and followed normal outcome.
Discussion and conclusion
The pH determination provides information only on the degree of acidemia and not on respiratory and/or metabolic components. Moreover, hypercapnia always present at birth is not included in the instructions to determine a metabolic acidosis (The American College of Obstetricians and Gynecologists, 2014; MacLennan et al., 2015). The new concept of neonatal eucapnic pH at birth accounts for only the metabolic component. We feel it should fine tune indications for cerebral hypothermia and thus improve its effectiveness. From a medicolegal perspective, for cases of cerebral palsy, it often allows to refute metabolic acidosis in perpartum events, often wrongfully being linked to generate cerebral injuries.
{"title":"Le pH eucapnique néonatal à la naissance : application à une cohorte de 5392 nouveau-nés","authors":"C. Racinet , J.-F. Peresse , G. Richalet , C. Corne , P. Ouellet","doi":"10.1016/j.gyobfe.2016.07.008","DOIUrl":"10.1016/j.gyobfe.2016.07.008","url":null,"abstract":"<div><h3>Objective</h3><p>To apply a newly concept of neonatal eucapnic pH at birth [pH euc (n)] and compare its contribution towards conventional criteria of severe metabolic acidosis.</p></div><div><h3>Methods</h3><p>Analysis of a cohort of 5392 neonates from 2010 to 2014 in a level 1 maternity. clinical data (birth weight, gestational age, mode of delivery, APGAR score) were collected from archived files. Biological data were collected from umbilical cord blood, consisting of pH, PCO<sub>2</sub>, Base deficit, lactate. Eucapnic pH and eucapnic base deficit were calculated from pH and PCO<sub>2</sub> with the Henderson-Hasselbalch equation applied in the Charles-Racinet diagram and/or with an Excel spreadsheet.</p></div><div><h3>Results</h3><p>Data set the prevalence of neonatal acidemia<!--> <!--><<!--> <!-->7.00 to 0.62 %. The current cohort shows 32 cases of severe neonatal metabolic acidosis according to ACOG-AAP (2014) criteria and 26/29 cases according to McLennan (2015) criteria, of which 80 % were born by cesarean section or instrumental delivery. In 55 % of cases, calculated eucapnic pH at birth did not confirm the severity of metabolic acidosis based on a threshold set at 7.11. Five cases were transferred in neonatalogy only on clinical considerations of poor neonatal adaptation but not on biological consideration (pH euc<!--> <!--><<!--> <!-->7.11 was equally distributed between transferred and non-transferred neonates, <em>P</em> <!-->=<!--> <!-->0.76; the same distribution was observed with the pH, <em>P</em> <!-->=<!--> <!-->0.20) and followed normal outcome.</p></div><div><h3>Discussion and conclusion</h3><p>The pH determination provides information only on the degree of acidemia and not on respiratory and/or metabolic components. Moreover, hypercapnia always present at birth is not included in the instructions to determine a metabolic acidosis (The American College of Obstetricians and Gynecologists, 2014; MacLennan et al., 2015). The new concept of neonatal eucapnic pH at birth accounts for only the metabolic component. We feel it should fine tune indications for cerebral hypothermia and thus improve its effectiveness. From a medicolegal perspective, for cases of cerebral palsy, it often allows to refute metabolic acidosis in perpartum events, often wrongfully being linked to generate cerebral injuries.</p></div>","PeriodicalId":55077,"journal":{"name":"Gynecologie Obstetrique & Fertilite","volume":"44 9","pages":"Pages 468-474"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gyobfe.2016.07.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34708817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-08-04DOI: 10.1016/J.GYOBFE.2016.03.006
J.-M. Jouannic, C. Huissoud
{"title":"Infection materno-fœtale par le virus Zika : quelle information pour les femmes enceintes ?","authors":"J.-M. Jouannic, C. Huissoud","doi":"10.1016/J.GYOBFE.2016.03.006","DOIUrl":"https://doi.org/10.1016/J.GYOBFE.2016.03.006","url":null,"abstract":"","PeriodicalId":55077,"journal":{"name":"Gynecologie Obstetrique & Fertilite","volume":"52 1","pages":"193-194"},"PeriodicalIF":0.0,"publicationDate":"2016-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80401396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-07-01DOI: 10.1016/j.gyobfe.2016.05.013
M. Le Chatton , C. Wittemer , T. Schweitzer , F. Lestrade , J.-P. Ragage
Objectives
The undeniable asset of the antagonist protocols in in vitro fertilization is the decrease of the risks of ovarian hyperstimulation syndrome, by the use of a release by GnRH agonist. Nevertheless, questioning persist concerning the rates of clinical pregnancies, the oocyte quantity and the empty follicle syndrome. We thus studied these parameters in our center.
Methods
A retrospective study was realized from January 1st, 2013 till July 31st, 2015. The main objective was the evaluation of the rate of clinical pregnancies in antagonist protocol. A first group of 775 cycles have benefited from a release of the ovulation by HCG, while a second group of 204 cycles, by GnRH agonist. The secondary objectives were the oocyte quantity, the rate of ovarian hyperstimulation syndrome, and the rate of empty follicle syndrome.
Results
No statistically significant difference was found between both groups concerning the rates of clinical pregnancies, oocytes quantity, and the rate of empty follicle syndrome, whatever is the type of used release, in fresh embryo transfer. A syndrome of premature ovarian hyperstimulation syndrome was found at 7.9 % of the patients in the group 2 versus 2.3 % in the group 1, with a statistically significant difference (P < 0.05). At these patients, a strategy of frozen embryo transfer (“freeze all”) was proposed. The accumulated rates by pregnancy in both groups were not statistically different.
Conclusion
The release by GnRH agonist does not show inferiority in terms of clinical pregnancy, in comparison to HCG.
{"title":"Le déclenchement par agonistes de la Gonadotropin releasing hormone (GnRH) est-il bénéfique ou délétère ?","authors":"M. Le Chatton , C. Wittemer , T. Schweitzer , F. Lestrade , J.-P. Ragage","doi":"10.1016/j.gyobfe.2016.05.013","DOIUrl":"10.1016/j.gyobfe.2016.05.013","url":null,"abstract":"<div><h3>Objectives</h3><p>The undeniable asset of the antagonist protocols in in vitro fertilization is the decrease of the risks of ovarian hyperstimulation syndrome, by the use of a release by GnRH agonist. Nevertheless, questioning persist concerning the rates of clinical pregnancies, the oocyte quantity and the empty follicle syndrome. We thus studied these parameters in our center.</p></div><div><h3>Methods</h3><p>A retrospective study was realized from January 1st, 2013 till July 31st, 2015. The main objective was the evaluation of the rate of clinical pregnancies in antagonist protocol. A first group of 775 cycles have benefited from a release of the ovulation by HCG, while a second group of 204 cycles, by GnRH agonist. The secondary objectives were the oocyte quantity, the rate of ovarian hyperstimulation syndrome, and the rate of empty follicle syndrome.</p></div><div><h3>Results</h3><p>No statistically significant difference was found between both groups concerning the rates of clinical pregnancies, oocytes quantity, and the rate of empty follicle syndrome, whatever is the type of used release, in fresh embryo transfer. A syndrome of premature ovarian hyperstimulation syndrome was found at 7.9 % of the patients in the group 2 versus 2.3 % in the group 1, with a statistically significant difference (<em>P</em> <!--><<!--> <!-->0.05). At these patients, a strategy of frozen embryo transfer (“freeze all”) was proposed. The accumulated rates by pregnancy in both groups were not statistically different.</p></div><div><h3>Conclusion</h3><p>The release by GnRH agonist does not show inferiority in terms of clinical pregnancy, in comparison to HCG.</p></div>","PeriodicalId":55077,"journal":{"name":"Gynecologie Obstetrique & Fertilite","volume":"44 7","pages":"Pages 403-409"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gyobfe.2016.05.013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34698704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-07-01DOI: 10.1016/j.gyobfe.2016.06.004
N.G. Cassuto
{"title":"Est-il utile d’observer les embryons aux stades précoces de leur développement quand une culture prolongée est effectuée ? Non","authors":"N.G. Cassuto","doi":"10.1016/j.gyobfe.2016.06.004","DOIUrl":"10.1016/j.gyobfe.2016.06.004","url":null,"abstract":"","PeriodicalId":55077,"journal":{"name":"Gynecologie Obstetrique & Fertilite","volume":"44 7","pages":"Pages 444-445"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gyobfe.2016.06.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34698702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-07-01DOI: 10.1016/j.gyobfe.2016.06.007
L. Komguem , P. Guilbert , M. Doublier , F. Guillemin
Objectives
In our study, we aimed to assess the pathologic complete response after neo-additive chemotherapy that contains a taxan associated to trastuzumab for patients treated from breast cancer at the institute Jean-Godinot between 2012 and 2014, and to evaluate factors associated to this pathologic complete response.
Methods
Retrospective study with clinical, anatomopathologic and radiologic parameters analysis before and after new adjuvant chemotherapy. The statistical analysis was done on logiciel XL-STAT, the Mann-Whitney-Wilcoxon for quantitative variables and Fisher exact tests for qualitative variables, the Spearman rang test.
Results
The rate of pathologic complete response is 38.8%. The prognostic factor associated to pathologic complete response is a Ki-67 > 44%.
Conclusion
The pathologic complete response rate corresponds to international lower rate; because of the lack of several data, we found out only one prognostic factor, Ki-67 > 44%.
{"title":"Étude de réponse histologique du cancer du sein HER2+ après chimiothérapie néoadjuvante associant taxane et trastuzumab","authors":"L. Komguem , P. Guilbert , M. Doublier , F. Guillemin","doi":"10.1016/j.gyobfe.2016.06.007","DOIUrl":"10.1016/j.gyobfe.2016.06.007","url":null,"abstract":"<div><h3>Objectives</h3><p>In our study, we aimed to assess the pathologic complete response after neo-additive chemotherapy that contains a taxan associated to trastuzumab for patients treated from breast cancer at the institute Jean-Godinot between 2012 and 2014, and to evaluate factors associated to this pathologic complete response.</p></div><div><h3>Methods</h3><p>Retrospective study with clinical, anatomopathologic and radiologic parameters analysis before and after new adjuvant chemotherapy. The statistical analysis was done on <em>logiciel</em> XL-STAT, the Mann-Whitney-Wilcoxon for quantitative variables and Fisher exact tests for qualitative variables, the Spearman rang test.</p></div><div><h3>Results</h3><p>The rate of pathologic complete response is 38.8%. The prognostic factor associated to pathologic complete response is a Ki-67<!--> <!-->><!--> <!-->44%.</p></div><div><h3>Conclusion</h3><p>The pathologic complete response rate corresponds to international lower rate; because of the lack of several data, we found out only one prognostic factor, Ki-67<!--> <!-->><!--> <!-->44%.</p></div>","PeriodicalId":55077,"journal":{"name":"Gynecologie Obstetrique & Fertilite","volume":"44 7","pages":"Pages 396-402"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gyobfe.2016.06.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34698703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-07-01DOI: 10.1016/j.gyobfe.2016.06.005
J.-M. Antoine
{"title":"Est-il utile d’observer les embryons aux stades précoces de leur développement quand une culture prolongée est effectuée ?","authors":"J.-M. Antoine","doi":"10.1016/j.gyobfe.2016.06.005","DOIUrl":"10.1016/j.gyobfe.2016.06.005","url":null,"abstract":"","PeriodicalId":55077,"journal":{"name":"Gynecologie Obstetrique & Fertilite","volume":"44 7","pages":"Page 440"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gyobfe.2016.06.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34698707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-07-01DOI: 10.1016/j.gyobfe.2016.06.006
J. Muraskas
{"title":"JK Muraskas in response to the article by C. Racinet et al. Neonatal metabolic acidosis at birth: In search of a reliable marker. Gynecol Obstet Fertil 2016; 44: 357–62","authors":"J. Muraskas","doi":"10.1016/j.gyobfe.2016.06.006","DOIUrl":"10.1016/j.gyobfe.2016.06.006","url":null,"abstract":"","PeriodicalId":55077,"journal":{"name":"Gynecologie Obstetrique & Fertilite","volume":"44 7","pages":"Pages 455-456"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gyobfe.2016.06.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34676444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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