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Both Sides, Now: A Personal Stroke Recovery Journey. 双方,现在:个人中风康复之旅。
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-01-06 DOI: 10.1017/S0963180124000641
Grant Gillett

This is a personal narrative of my stroke and recovery experience, and the medical, psychological, and social circumstances surrounding it.

这是我对中风和康复经历的个人叙述,以及围绕它的医疗、心理和社会环境。
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引用次数: 0
Neural Voices of Patients with Severe Brain Injury? 重型颅脑损伤患者的神经声音?
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-01-03 DOI: 10.1017/S0963180124000446
Matthew Owen, Darren Hight, Anthony G Hudetz

Studies have shown that some covertly conscious brain-injured patients, who are behaviorally unresponsive, can reply to simple questions via neuronal responses. Given the possibility of such neuronal responses, Andrew Peterson et al. have argued that there is warrant for some covertly conscious patients being included in low-stakes medical decisions using neuronal responses, which could protect and enhance their autonomy. The justification for giving credence to alleged neuronal responses must be analyzed from various perspectives, including neurology, bioethics, law, and as we suggest, philosophy of mind. In this article, we analyze the warrant for giving credence to neuronal responses from two different views in philosophy of mind. We consider how nonreductive physicalism's causal exclusion problem elicits doubt about interpreting neural activity as indicating a conscious response. By contrast, such an interpretation is supported by the mind-body powers model of neural correlates of consciousness inspired by hylomorphism.

研究表明,一些无意识的脑损伤患者,他们的行为没有反应,可以通过神经元反应回答简单的问题。考虑到这种神经元反应的可能性,Andrew Peterson等人认为,有理由让一些潜意识清醒的患者使用神经元反应参与低风险的医疗决策,这可以保护和增强他们的自主权。相信所谓的神经元反应的理由必须从不同的角度进行分析,包括神经学、生物伦理学、法律,以及我们建议的心灵哲学。在这篇文章中,我们从心灵哲学的两种不同观点分析了相信神经元反应的理由。我们考虑非还原性物理主义的因果排斥问题如何引起对将神经活动解释为表明有意识反应的怀疑。相比之下,这种解释得到了意识的神经关联的身心力量模型的支持,该模型受到形态学说的启发。
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引用次数: 0
Setting Limits for the Principle of Equal Entitlement to Continued Life. 为延续生命的平等权利原则设限。
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-01-02 DOI: 10.1017/S0963180124000768
Juan D Moreno-Ternero, Lars Peter Østerdal

The normative principle that every individual is equally entitled to continued life is a subject of debate in ethics, health economics and policy. We reconsider this principle in the context of setting priorities for healthcare interventions. When applied without restriction, the principle overlooks quality of life concerns entirely. However, we contend that it remains ethically relevant in certain situations, particularly when patients suffer from conditions unrelated to the therapeutic areas and treatments under consideration. Thus, we defend the principle while also emphasizing the need for its application within tight limits.

人人平等有权继续生活这一规范性原则是伦理、卫生经济学和政策领域辩论的主题。我们重新考虑这一原则在背景下确定优先事项的医疗干预措施。如果不加限制地应用,这一原则就完全忽视了生活质量问题。然而,我们认为,在某些情况下,特别是当患者患有与治疗领域和治疗无关的疾病时,它在伦理上仍然是相关的。因此,我们捍卫这一原则,同时也强调必须在严格的范围内适用这一原则。
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引用次数: 0
That Is My Mind. 这就是我的思想。
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-11 DOI: 10.1017/S0963180124000690
Robert Burton
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引用次数: 0
Ghost in the Machine. 机器里的幽灵。
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-10 DOI: 10.1017/S0963180124000677
Robert A Burton

Delisted in the building directory, my name stripped from my cramped quarters just off the corpus callosum, I am impossible to find. In petitioning for official reinstatement, I have agreed to the humiliating lab investigations required for documentation. I have waved, howled, screamed, pleaded, and moaned into the latest scanners, and generally made a fool of myself. But researchers, after extensive soul-searching, and being unable to capture me as pixels and waveforms, have moved on to greener pastures. So be it. I accept official non-existence.

我的名字被从大楼名录中除名了,我的名字被从我狭小的住处中除名了,就在脑胼胝体旁边,我不可能被找到。在申请正式复职的过程中,我已经同意进行屈辱的实验室调查。我对着最新的扫描仪挥手、嚎叫、尖叫、哀求、呻吟,总让自己出丑。但研究人员在进行了广泛的灵魂探索之后,无法以像素和波形的形式捕捉到我,于是他们转向了更广阔的领域。那就这样吧。我接受官方的不存在。
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引用次数: 0
Written in Stone. 石头上写的。
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-10 DOI: 10.1017/S0963180124000689
Robert A Burton

While the Big Bang was cooling and the laws of physics were congealing, authorities remained undecided whether God would provide comfort against the expanding darkness. To answer the question, one planet was seeded with humans equipped with conviction receptors tweaked either to an absolute faith in or complete denial of God. If, after a suitable period of mingling between the two groups, believers prevailed over doubters, God would be established in the firmament. If not, God would be scrapped.

当宇宙大爆炸正在冷却,物理定律正在凝结的时候,权威人士仍然不确定上帝是否会在不断膨胀的黑暗中提供安慰。为了回答这个问题,一个星球上的人类被配备了信念感受器,这些感受器被调整为对上帝的绝对信仰或完全否认。如果信仰者战胜了怀疑者,经过一段适当的时间,信仰者就会在天空中扎根。否则,上帝就会被废弃。
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引用次数: 0
Wounds and Vulnerabilities. The Participation of Special Operations Forces in Experimental Brain-Computer Interface Research. 创伤和脆弱性。特种作战部队参与脑机接口实验研究。
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-04 DOI: 10.1017/S096318012400063X
Anna M Gielas

Brain-computer interfaces (BCIs) exemplify a dual-use neurotechnology with significant potential in both civilian and military contexts. While BCIs hold promise for treating neurological conditions such as spinal cord injuries and amyotrophic lateral sclerosis in the future, military decisionmakers in countries such as the United States and China also see their potential to enhance combat capabilities. Some predict that U.S. Special Operations Forces (SOF) will be early adopters of BCI enhancements. This article argues for a shift in focus: the U.S. Special Operations Command (SOCOM) should pursue translational research of medical BCIs for treating severely injured or ill SOF personnel. After two decades of continuous military engagement and on-going high-risk operations, SOF personnel face unique injury patterns, both physical and psychological, which BCI technology could help address. The article identifies six key medical applications of BCIs that could benefit wounded SOF members and discusses the ethical implications of involving SOF personnel in translational research related to these applications. Ultimately, the article challenges the traditional civilian-military divide in neurotechnology, arguing that by collaborating more closely with military stakeholders, scientists can not only help individuals with medical needs, including servicemembers, but also play a role in shaping the future military applications of BCI technology.

脑机接口(bci)是一种军民两用的神经技术,在民用和军事领域都具有巨大的潜力。虽然脑机接口有望在未来治疗脊髓损伤和肌萎缩侧索硬化症等神经系统疾病,但美国和中国等国的军事决策者也看到了它们增强作战能力的潜力。一些人预测,美国特种作战部队(SOF)将是BCI增强技术的早期采用者。本文主张转移焦点:美国特种作战司令部(SOCOM)应该进行医疗脑机接口的转化研究,以治疗严重受伤或生病的特种作战人员。经过二十年的持续军事接触和持续的高风险行动,SOF人员面临着独特的身体和心理伤害模式,BCI技术可以帮助解决这一问题。本文确定了六种可以使受伤的SOF成员受益的bci的关键医疗应用,并讨论了涉及SOF人员与这些应用相关的转化研究的伦理问题。最后,这篇文章挑战了传统的军民神经技术鸿沟,认为通过与军事利益相关者更密切地合作,科学家不仅可以帮助有医疗需求的个人,包括军人,还可以在塑造BCI技术未来的军事应用中发挥作用。
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引用次数: 0
How to Make Psychedelic-Assisted Therapy Safer. 如何使迷幻辅助治疗更安全。
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-02 DOI: 10.1017/S0963180124000604
Daniel Villiger

Classic serotonergic psychedelics are experiencing a clinical revival, which has also revived ethical debates about psychedelic-assisted therapy. A particular issue here is how to prepare and protect patients from the vulnerability that the psychedelic state creates. This article first examines how this vulnerability manifests itself, revealing that it results from an impairment of autonomy: psychedelics diminish decision-making capacity, reduce controllability, and limit resistance to external influences. It then analyzes the strengths and weaknesses of five safety measures proposed in the literature, what aspect of the patient's vulnerability they seek to reduce, and how they can be optimized. The analysis shows that while preparatory sessions, advance directives, and specific training and oversight are useful, starting with a lower dosage and no therapy is less so. Finally, the article presents a safety measure that has been overlooked in the literature but could be highly effective and feasible: bringing a close person to the psychedelic session.

经典的5 -羟色胺致幻剂正在经历临床复苏,这也重新引发了关于致幻剂辅助治疗的伦理辩论。这里的一个特别问题是如何准备和保护病人免受迷幻状态造成的脆弱性。本文首先研究了这种脆弱性是如何表现出来的,揭示了它是由自主性受损引起的:迷幻药降低了决策能力,降低了可控性,并限制了对外部影响的抵抗力。然后分析了文献中提出的五种安全措施的优缺点,他们寻求减少患者脆弱性的哪些方面,以及如何优化它们。分析表明,虽然预备会议、预先指示以及具体培训和监督是有用的,但从较低剂量开始和不进行治疗就不那么有用了。最后,这篇文章提出了一种在文献中被忽视的安全措施,但它可能是非常有效和可行的:带一个亲密的人去迷幻疗程。
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引用次数: 0
The Roles of Understanding and Belief in Prognostic Awareness. 理解和信念在预后意识中的作用。
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-11-22 DOI: 10.1017/S0963180124000628
Alexander T Yahanda, Bryan A Sisk

Conventional understanding and research regarding prognostic understanding too often focuses on transmission of information. However, merely overcoming barriers to patient understanding may not be sufficient. In this article the authors provide a more nuanced understanding of prognostic awareness, using oncological care as an overarching example, and discuss factors that may lead to prognostic discordance between physicians and patients. We summarize the current literature and research and present a model developed by the authors to characterize barriers to prognostic awareness. Ultimately, multiple influences on prognostic understanding may impede acceptance by patients even when adequate transfer of information takes place. Physicians should improve how they transmit prognostic information, as this information may be processed in different ways. A model of misunderstandings in awareness, ranging from patient understanding to patient belief, may be useful to guide future discussions. Future decision-making studies should consider these many variables so that interventions may be created to address all aspects of the prognostic disclosure process.

有关预后理解的传统认识和研究往往侧重于信息传递。然而,仅仅克服患者理解方面的障碍可能还不够。在这篇文章中,作者以肿瘤治疗为例,对预后意识进行了更细致的理解,并讨论了可能导致医生和患者之间预后不一致的因素。我们总结了当前的文献和研究,并提出了作者开发的一个模型来描述预后意识的障碍。最终,对预后认识的多种影响因素可能会阻碍患者对预后的接受,即使在信息传递充分的情况下也是如此。医生应该改进他们传递预后信息的方式,因为这些信息可能会以不同的方式进行处理。从患者理解到患者信念的认知误区模型可能有助于指导未来的讨论。未来的决策研究应考虑这些变量,以便制定干预措施,解决预后信息披露过程中的各方面问题。
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引用次数: 0
Personhood, Dementia, and Bioethics. 人格、痴呆症与生命伦理学。
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-11-11 DOI: 10.1017/S0963180124000513
Steve Matthews

Jennifer Blumenthal-Barby (2024) has called for bioethics to end talk about personhood, asserting that such talk has the tendency to confuse and offend. It will be argued that this has only limited application for (largely) private settings. However, in other settings, theorizing about personhood leaves a gap in which there is the risk that the offending concept will get uptake elsewhere, and so the problem Blumenthal-Barby nominates may not be completely avoided. In response to this risk, an argument is presented in support of the idea that the role of philosophers and bioethicists, far from ending talk of personhood, ought to be to clarify the concept, and to do so in nuanced ways, given its application for specific kinds of impairments. The case of dementia is used to illustrate this in the context of person-centered care. Ironically, given the stigma attached to dementia, far from the need to end talk of personhood, bioethicists are needed to rescue the concept and clarify its role.

珍妮弗-布卢门塔尔-巴尔比(Jennifer Blumenthal-Barby,2024 年)呼吁生命伦理学停止谈论人的身份,并断言这种谈论容易造成混淆和冒犯。本文将论证这一点在(大部分)私人场合的适用范围有限。然而,在其他情况下,关于人格的理论化会留下一个缺口,在这个缺口中,违规的概念有可能会在其他地方得到采纳,因此,布卢门塔尔-巴尔比提出的问题可能无法完全避免。为了应对这种风险,我们提出了一个论点,支持哲学家和生命伦理学家的作用远非终止关于人格的讨论,而是应该澄清这一概念,并以细致入微的方式澄清这一概念,因为它适用于特定类型的损伤。本文以痴呆症为例,从以人为本的护理角度说明了这一点。具有讽刺意味的是,考虑到痴呆症所带来的耻辱感,生物伦理学家不仅不需要终止关于人格的讨论,反而需要拯救这一概念并澄清其作用。
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Cambridge Quarterly of Healthcare Ethics
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