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The Geneticization of Education and Its Bioethical Implications. 教育的基因化及其生物伦理影响。
IF 2.3 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-11-07 DOI: 10.1017/S096318012400046X
Lucas J Matthews

The day has arrived that genetic tests for educational outcomes are available to the public. Today parents and students alike can send off a sample of blood or saliva and receive a 'genetic report' for a range of characteristics relevant to education, including intelligence, math ability, reading ability, and educational attainment. DTC availability is compounded by a growing "precision education" initiative, which proposes the application of DNA tests in schools to tailor educational curricula to children's genomic profiles. Here I argue that these happenings are a strong signal of the geneticization of education; the process by which educational abilities and outcomes come to be examined, understood, explained, and treated as primarily genetic characteristics. I clarify what it means to geneticize education, highlight the nature and limitations of the underlying science, explore both real and potential downstream bioethical implications, and make proposals for mitigating negative impacts.

公众也能进行教育成果基因测试的日子已经到来。如今,家长和学生都可以寄送血液或唾液样本,获得与教育相关的一系列特征的 "基因报告",包括智力、数学能力、阅读能力和受教育程度。除了 DTC 之外,"精准教育 "计划也在不断发展,该计划提出在学校应用 DNA 测试,根据儿童的基因组特征调整教育课程。在此,我认为这些事件是教育遗传化的一个强烈信号;教育能力和教育成果主要是作为遗传特征来考察、理解、解释和处理的。我将阐明教育基因化的含义,强调基础科学的性质和局限性,探讨现实和潜在的下游生物伦理影响,并提出减轻负面影响的建议。
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引用次数: 0
In Defense of "Physician-Assisted Suicide": Toward (and Back to) a Transparent, Destigmatizing Debate. 为 "医生协助自杀 "辩护:走向(和回归)一场透明的、去污名化的辩论。
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-11-07 DOI: 10.1017/S0963180124000434
Brandy M Fox, Harold Braswell

Many bioethicists have recently shifted from using "physician-assisted suicide" (PAS) to "medical aid-in-dying" (MAID) to refer to the act of voluntarily hastening one's death with the assistance of a medical provider. This shift was made to obscure the practice's connection to "suicide." However, as the charge of "suicide" is fundamental to arguments against the practice, "MAID" can only be used by its proponents. The result has been the fragmentation of the bioethical debate. By highlighting the role of human agency-as opposed to natural processes-in causing death, the term "PAS" makes it easier both to perceive potential risks to vulnerable populations and to affirm suicide as a potentially autonomous choice. As such, "PAS" thus more transparently expresses the arguments of both supporters and opponents of the "right to die," while avoiding the unnecessary stigmatization of suicide and suicidal people which is a result of the usage of "MAID."

许多生物伦理学家最近将 "医生协助自杀"(PAS)改为 "医疗协助死亡"(MAID),以指代在医疗服务提供者的协助下自愿加速死亡的行为。这一转变是为了掩盖这种做法与 "自杀 "的联系。然而,由于 "自杀 "指控是反对这种做法的基本论据,因此 "MAID "只能由其支持者使用。结果导致生物伦理辩论支离破碎。通过强调人的主观能动性--而不是自然过程--在导致死亡方面的作用,"PAS "一词使人们更容易认识到对弱势群体的潜在风险,也更容易肯定自杀是一种潜在的自主选择。因此,"PAS "一词更透明地表达了 "死亡权 "支持者和反对者的论点,同时避免了因使用 "MAID "一词而对自杀和有自杀倾向的人造成不必要的污名化。
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引用次数: 0
"Terminal Anorexia", Treatment Refusal and Decision-Making Capacity. "临终厌食症"、拒绝治疗和决策能力。
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-10-28 DOI: 10.1017/S0963180124000367
Anneli Jefferson

Whether anorexic patients should be able to refuse treatment when this refusal potentially has a fatal outcome is a vexed topic. A recent proposal for a new category of "terminal anorexia" suggests criteria when a move to palliative care or even physician-assisted suicide might be justified. The author argues that this proposed diagnosis presents a false sense of certainty of the illness trajectory by conceptualizing anorexia in analogy with physical disorders and stressing the effects of starvation. Furthermore, this conceptualization is in conflict with the claim that individuals who meet the diagnostic criteria for terminal anorexia have decision-making capacity. It should therefore be rejected.

厌食症患者在拒绝治疗可能导致致命后果的情况下是否应该拒绝治疗,这是一个令人困扰的话题。最近有人提出了一个新的 "临终厌食症 "类别,它提出了在什么情况下可以采取姑息治疗甚至医生协助自杀的标准。作者认为,这一诊断建议将厌食症与躯体疾病相类比,并强调饥饿的影响,从而对疾病的发展轨迹产生了错误的确定感。此外,这一概念与符合临终厌食症诊断标准的个体具有决策能力的说法相冲突。因此应予以摒弃。
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引用次数: 0
Invisible Victims and the Case for OTC SSRIs. 隐形受害者和非处方药 SSRIs 案例。
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-10-22 DOI: 10.1017/S096318012400032X
Jacob M Appel

Major depressive disorder is one of the most common serious illnesses worldwide; the disease is also among those with the lowest rates of treatment. Barriers to access to care, both practical and psychological, contribute significantly to these low treatment rates. Among such barriers are regulations in many nations that require a physician's prescription for most pharmacological treatments including selective serotonin reuptake inhibitors (SSRIs). These rules are designed to protect patients. However, such regulations involve a tradeoff between the welfare of "visible" victims, who might suffer negative consequences from a lack of regulation, and the well-being of invisible "victims," who likely experience negative consequences that result from increased barriers to care. This article explores these tradeoffs and argues in favor of shifting SSRIs from prescription-only to over-the-counter status.

重度抑郁障碍是全球最常见的严重疾病之一,也是治疗率最低的疾病之一。获得治疗的障碍,包括实际障碍和心理障碍,是造成治疗率低的重要原因。在这些障碍中,许多国家规定,包括选择性血清素再摄取抑制剂(SSRIs)在内的大多数药物治疗都需要医生处方。这些规定旨在保护患者。然而,这些规定涉及 "看得见的 "受害者的福利与看不见的 "受害者 "的福利之间的权衡,"看得见的 "受害者可能会因为缺乏监管而遭受负面影响,而看不见的 "受害者 "则可能会因为治疗障碍的增加而遭受负面影响。本文探讨了这些权衡,并主张将 SSRIs 从处方药转为非处方药。
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引用次数: 0
Interprofessional Ethics Simulations and Debriefing to Develop Collaborative Skills 跨专业伦理模拟和汇报,培养协作技能
IF 1.8 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-09-16 DOI: 10.1017/s096318012400029x
Amy Haddad, Kimberley Begley, Ann Ryan Haddad

The Interprofessional Education Collaborative’s (IPEC’s) core competencies are accreditation standards of most, if not all, healthcare professions (Interprofessional Education Collaborative Expert Panel [2016, Core Competencies for Interprofessional Collaborative Practice: 2016 Update. Washington, DC: IPEC]). Limited literature exists on interprofessional (IP) learning outcomes in healthcare ethics; even fewer studies include debrief sessions. Interprofessional education (IPE) case discussion using web-based technology is a promising way to incorporate ethics content. This article summarizes a model for healthcare programs to create, conduct, and assess synchronous IPE ethics discussions and debrief sessions. Specifically, this article highlights debrief sessions that followed a standardized patient (SP) IP interaction with students from pharmacy and advanced practice nursing. Qualitative analysis of debrief comments identified four themes: the benefit of IP collaboration, the importance of patient-centered care, the need to adapt clinical recommendations with ethical challenges, and the importance of trust among team members. The findings indicate web-based, synchronous IP/SP ethics simulations and debrief sessions are an effective, albeit laborious, method for collaboration and reflection.

跨专业教育合作组织(IPEC)的核心能力是大多数(如果不是全部)医疗保健专业的认证标准(跨专业教育合作组织专家小组[2016,跨专业合作实践的核心能力:2016年更新。华盛顿特区:IPEC])。有关跨专业(IP)医疗保健伦理学学习成果的文献有限;包含汇报环节的研究更是少之又少。使用网络技术进行跨专业教育(IPE)案例讨论是纳入伦理内容的一种很有前景的方法。本文总结了医疗保健项目创建、开展和评估同步 IPE 伦理学讨论和汇报环节的模式。具体而言,本文重点介绍了与药学和高级实践护理专业学生进行标准化病人(SP)IP 互动后的汇报环节。对汇报评论的定性分析确定了四个主题:IP 合作的益处、以患者为中心的护理的重要性、根据伦理挑战调整临床建议的必要性以及团队成员之间信任的重要性。研究结果表明,基于网络的同步 IP/SP 伦理模拟和汇报会是一种有效的协作和反思方法,尽管这种方法很费力。
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引用次数: 0
Why Not Phase Out Animal Experimentation? Considering Objections from Freedom of Inquiry and Cross-Border Displacement 为什么不逐步停止动物实验?考虑来自调查自由和跨境流离失所的反对意见
IF 1.8 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-09-13 DOI: 10.1017/s0963180124000288
Nico D. Müller

Animal experimentation raises value conflicts between animal protection and other goods, such as freedom of inquiry or health and safety. If governments can phase out the practice by non-prohibitive incentive-setting, the pro tanto moral rationale for doing so is obvious. So why should they not? This article first sketches a fictional scenario in which a government adopts a phase-out plan for animal experimentation. It then considers two moral objections to this plan: First, the plan unduly restricts freedom of inquiry, and second, it merely displaces animal experimentation across borders and thus fails to reduce animal suffering. Both arguments are refined premise by premise to articulate their strongest versions. The two objections can help to narrow down desiderata for good phase-out plans. However, they do not provide a compelling case against phase-out planning as such because they miss its incremental and constructive nature. Unless better arguments can be provided, it appears that government inaction on phasing out animal experimentation lacks moral justification.

动物实验引发了动物保护与其他商品(如探究自由或健康与安全)之间的价值冲突。如果政府可以通过非禁止性的激励措施逐步淘汰这种做法,那么这样做的道德理由是显而易见的。那么,为什么不这样做呢?本文首先勾勒了一个虚构的场景,在这个场景中,政府通过了一项逐步淘汰动物实验的计划。然后,文章考虑了对该计划的两种道德反对意见:首先,该计划不适当地限制了探究自由;其次,它只是将动物实验转移到了国外,因此无法减少动物的痛苦。这两个论点被逐一细化,以阐明其最有力的版本。这两种反对意见有助于缩小好的逐步淘汰计划的考虑范围。然而,它们并没有提供一个令人信服的理由来反对淘汰计划,因为它们忽略了其渐进性和建设性的本质。除非能够提供更好的论据,否则政府在逐步淘汰动物实验方面的不作为似乎缺乏道德理由。
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引用次数: 0
Xenotransplantation Clinical Trials and Equitable Patient Selection. 异种移植临床试验和公平的患者选择。
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-01 Epub Date: 2023-10-05 DOI: 10.1017/S096318012300052X
Christopher Bobier, Daniel Rodger

Xenotransplant patient selection recommendations restrict clinical trial participation to seriously ill patients for whom alternative therapies are unavailable or who will likely die while waiting for an allotransplant. Despite a scholarly consensus that this is advisable, we propose to examine this restriction. We offer three lines of criticism: (1) The risk-benefit calculation may well be unfavorable for seriously ill patients and society; (2) the guidelines conflict with criteria for equitable patient selection; and (3) the selection of seriously ill patients may compromise informed consent. We conclude by highlighting how the current guidance reveals a tension between the societal values of justice and beneficence.

异种移植患者选择建议将临床试验的参与限制在无法获得替代疗法或可能在等待同种移植时死亡的重病患者。尽管学术界一致认为这是可取的,但我们建议对这一限制进行审查。我们提出了三条批评:(1)风险收益的计算很可能对重病患者和社会不利;(2) 该指南与公平选择患者的标准相冲突;以及(3)选择重病患者可能会影响知情同意。最后,我们强调了当前的指导意见如何揭示了正义和慈善的社会价值观之间的紧张关系。
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引用次数: 0
Ethics Education in Health Sciences Should Engage Contentious Social Issues: Here Is Why and How. 健康科学伦理教育应涉及有争议的社会问题:原因和方法如下。
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-01 Epub Date: 2024-01-04 DOI: 10.1017/S0963180123000567
Jon Tilburt, Fred Hafferty, Andrea Leep Hunderfund, Ellen Meltzer, Bjorg Thorsteinsdottir

Teaching ethics is crucial to health sciences education. Doing it well requires a willingness to engage contentious social issues. Those issues introduce conflict and risk, but avoiding them ignores moral diversity and renders the work of ethics education irrelevant. Therefore, when (not if) contentious issues and moral differences arise, they must be acknowledged and can be addressed with humility, collegiality, and openness to support learning. Faculty must risk moments when not everyone will "feel safe," so the candor implied in psychological safety can emerge. The deliberative and social work of ethics education involves generous listening, wading into difference, and wondering together if our beliefs and arguments are as sound as we once thought. By forecasting the need for candid engagement with contentious issues and moral difference, establishing ground rules, and bolstering due process structures for faculty and students, a riskier and more relevant ethics pedagogy can emerge. Doing so will prepare everyone for the moral diversity they can expect in our common life and in practice.

伦理教学对健康科学教育至关重要。要做好这项工作,就必须愿意面对有争议的社会问题。这些问题会带来冲突和风险,但回避它们就会忽视道德的多样性,使伦理教育工作失去意义。因此,当(而不是如果)出现有争议的问题和道德分歧时,必须承认它们的存在,并以谦逊、合作和开放的态度加以解决,以支持学习。教师必须冒着并非每个人都会 "感到安全 "的风险,这样,心理安全所隐含的坦诚才能显现出来。伦理教育的商议和社会工作涉及倾听、涉足分歧,以及共同思考我们的信念和论点是否像我们曾经认为的那样正确。通过预测对有争议的问题和道德分歧的坦诚参与的需求,建立基本规则,并加强教师和学生的正当程序结构,一种更具风险性和相关性的伦理学教学法就会出现。这样做将使每个人做好准备,迎接我们共同生活和实践中的道德多样性。
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引用次数: 0
The Virtues of Interpretable Medical AI. 可解释医疗人工智能的优点。
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-01 Epub Date: 2023-01-10 DOI: 10.1017/S0963180122000664
Joshua Hatherley, Robert Sparrow, Mark Howard

Artificial intelligence (AI) systems have demonstrated impressive performance across a variety of clinical tasks. However, notoriously, sometimes these systems are "black boxes." The initial response in the literature was a demand for "explainable AI." However, recently, several authors have suggested that making AI more explainable or "interpretable" is likely to be at the cost of the accuracy of these systems and that prioritizing interpretability in medical AI may constitute a "lethal prejudice." In this paper, we defend the value of interpretability in the context of the use of AI in medicine. Clinicians may prefer interpretable systems over more accurate black boxes, which in turn is sufficient to give designers of AI reason to prefer more interpretable systems in order to ensure that AI is adopted and its benefits realized. Moreover, clinicians may be justified in this preference. Achieving the downstream benefits from AI is critically dependent on how the outputs of these systems are interpreted by physicians and patients. A preference for the use of highly accurate black box AI systems, over less accurate but more interpretable systems, may itself constitute a form of lethal prejudice that may diminish the benefits of AI to-and perhaps even harm-patients.

人工智能(AI)系统在各种临床任务中的表现令人印象深刻。然而,众所周知,这些系统有时是 "黑盒子"。文献中最初的回应是要求 "可解释的人工智能"。然而,最近有几位作者提出,提高人工智能的可解释性或 "可解释性 "很可能会以牺牲这些系统的准确性为代价,而且在医学人工智能中优先考虑可解释性可能会构成 "致命的偏见"。在本文中,我们将结合人工智能在医学中的应用,为可解释性的价值进行辩护。临床医生可能更喜欢可解释的系统,而不是更精确的黑盒子,这反过来又足以让人工智能的设计者有理由更喜欢可解释的系统,以确保人工智能被采用并实现其优势。此外,临床医生也有理由这样做。要实现人工智能的下游效益,关键取决于医生和患者如何解读这些系统的输出结果。偏好使用高度精确的黑盒人工智能系统,而不是精确度较低但可解释性更强的系统,这本身就可能构成一种致命的偏见,可能会减少人工智能给患者带来的益处,甚至可能对患者造成伤害。
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引用次数: 0
Learning to Live with Strange Error: Beyond Trustworthiness in Artificial Intelligence Ethics. 学会与奇怪的错误共存:超越人工智能伦理中的可信性》。
IF 1.5 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-01 Epub Date: 2023-01-09 DOI: 10.1017/S0963180122000688
Charles Rathkopf, Bert Heinrichs

Position papers on artificial intelligence (AI) ethics are often framed as attempts to work out technical and regulatory strategies for attaining what is commonly called trustworthy AI. In such papers, the technical and regulatory strategies are frequently analyzed in detail, but the concept of trustworthy AI is not. As a result, it remains unclear. This paper lays out a variety of possible interpretations of the concept and concludes that none of them is appropriate. The central problem is that, by framing the ethics of AI in terms of trustworthiness, we reinforce unjustified anthropocentric assumptions that stand in the way of clear analysis. Furthermore, even if we insist on a purely epistemic interpretation of the concept, according to which trustworthiness just means measurable reliability, it turns out that the analysis will, nevertheless, suffer from a subtle form of anthropocentrism. The paper goes on to develop the concept of strange error, which serves both to sharpen the initial diagnosis of the inadequacy of trustworthy AI and to articulate the novel epistemological situation created by the use of AI. The paper concludes with a discussion of how strange error puts pressure on standard practices of assessing moral culpability, particularly in the context of medicine.

关于人工智能(AI)伦理的立场文件往往是试图制定技术和监管策略,以实现通常所说的可信赖的人工智能。在这些文件中,技术和监管战略经常得到详细分析,但值得信赖的人工智能的概念却没有得到分析。因此,这一概念仍不明确。本文列出了对这一概念的各种可能解释,并得出结论认为,这些解释都不恰当。核心问题在于,通过从可信度的角度来阐述人工智能伦理,我们强化了不合理的人类中心主义假设,阻碍了清晰的分析。此外,即使我们坚持对这一概念进行纯粹的认识论解释,即可信度只是指可测量的可靠性,但结果表明,这种分析仍然会受到一种微妙的人类中心主义的影响。本文接着提出了 "奇怪的错误"(range error)这一概念,它既有助于进一步明确对值得信赖的人工智能不足之处的初步诊断,也有助于阐明人工智能的使用所带来的新的认识论局面。论文最后讨论了奇怪的错误如何对评估道德罪责的标准做法造成压力,特别是在医学方面。
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引用次数: 0
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Cambridge Quarterly of Healthcare Ethics
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