Pub Date : 2022-01-01DOI: 10.37360/blacpma.22.21.4.29
A. Parlar, Rabia Edibe Parlar Koprulu, S. Arslan, S. Cam, Fidan Pesen Ozdogan, O. Yumrutas, F. Uckardes, Miguel Rios, Jose L. Martinez
The aim of this study was to evaluate the functional interaction of Glycyrrhiza glabraroot extract (GGRE) on the large conductance Ca2+-activated K+(BKCa) channels expressed in the peripheral nervous system by using nociception and inflammation models in rodents in vivo. Besides toxicity studies and open field tests, nociception and inflammation tests were performed on rodents. Different doses of GGRE were given orally to rats and mice. Naloxone, indomethacin, morphine, NS1619 and iberiotoxin (IbTX) were administered. GGRE had both anti-nociceptive and anti-inflammatory activity in rats and mice. GGRE exhibited an analgesic effect by decreasing the time-course of the pain threshold or reaction time insome nociceptive tests. Furthermore, GGRE reduced level of pro-inflammatory cytokines, including TNF-α and IL-1β. As a conclusion, GGRE can alleviate the pain sensation of the afferent nerves and can reduce inflammation and associated pain by activating BKCa channels and reducing the levels of TNF-α, IL1β.
{"title":"Extract of Glycyrrhiza glabraroot attenuates nociception in experimental pain models: The role of BKCa channels","authors":"A. Parlar, Rabia Edibe Parlar Koprulu, S. Arslan, S. Cam, Fidan Pesen Ozdogan, O. Yumrutas, F. Uckardes, Miguel Rios, Jose L. Martinez","doi":"10.37360/blacpma.22.21.4.29","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.4.29","url":null,"abstract":"The aim of this study was to evaluate the functional interaction of Glycyrrhiza glabraroot extract (GGRE) on the large conductance Ca2+-activated K+(BKCa) channels expressed in the peripheral nervous system by using nociception and inflammation models in rodents in vivo. Besides toxicity studies and open field tests, nociception and inflammation tests were performed on rodents. Different doses of GGRE were given orally to rats and mice. Naloxone, indomethacin, morphine, NS1619 and iberiotoxin (IbTX) were administered. GGRE had both anti-nociceptive and anti-inflammatory activity in rats and mice. GGRE exhibited an analgesic effect by decreasing the time-course of the pain threshold or reaction time insome nociceptive tests. Furthermore, GGRE reduced level of pro-inflammatory cytokines, including TNF-α and IL-1β. As a conclusion, GGRE can alleviate the pain sensation of the afferent nerves and can reduce inflammation and associated pain by activating BKCa channels and reducing the levels of TNF-α, IL1β.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"102 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88996150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.37360/blacpma.22.21.2.09
Andreia F. M. Santos, Marília Moraes Queiroz Souza, K. Pauli, Gustavo Ratti da Silva, Midia Wolff Marques, P. A. Auth, W. Bortolucci, Z. C. Gazim, G. Linde, N. Colauto, E. C. W. Lovato, F. Lívero
Bacopa monnieri(L.) Wettst. (Plantaginaceae), also known as Brahmi, has been used to improve cognitive processes and intellectual functions that are related to the preservation of memory. The objective of this research is to review the ethnobotanical applications, phytochemical composition, toxicity and activity of B. monnieriin the central nervous system. It reviewed articles on B. monnieriusing Google Scholar, SciELO, Science Direct, Lilacs, Medline, and PubMed. Saponins are the main compounds in extracts of B. monnieri. Pharmacological studies showed that B. monnieriimproves learning and memory and presents biological effects against Alzheimer’s disease, Parkinson’s disease, epilepsy, and schizophrenia. No preclinical acute toxicity was reported. However, gastrointestinal side effects were reported in some healthy elderly individuals. Most studies with B. monnierihave been preclinical evaluations of cellular mechanisms in the central nervous system and further translational clinical research needs to be performed to evaluate the safety and efficacy of the plant.
{"title":"Bacopa monnieri: Historical aspects to promising pharmacological actions for the treatment of central nervous system diseases","authors":"Andreia F. M. Santos, Marília Moraes Queiroz Souza, K. Pauli, Gustavo Ratti da Silva, Midia Wolff Marques, P. A. Auth, W. Bortolucci, Z. C. Gazim, G. Linde, N. Colauto, E. C. W. Lovato, F. Lívero","doi":"10.37360/blacpma.22.21.2.09","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.2.09","url":null,"abstract":"Bacopa monnieri(L.) Wettst. (Plantaginaceae), also known as Brahmi, has been used to improve cognitive processes and intellectual functions that are related to the preservation of memory. The objective of this research is to review the ethnobotanical applications, phytochemical composition, toxicity and activity of B. monnieriin the central nervous system. It reviewed articles on B. monnieriusing Google Scholar, SciELO, Science Direct, Lilacs, Medline, and PubMed. Saponins are the main compounds in extracts of B. monnieri. Pharmacological studies showed that B. monnieriimproves learning and memory and presents biological effects against Alzheimer’s disease, Parkinson’s disease, epilepsy, and schizophrenia. No preclinical acute toxicity was reported. However, gastrointestinal side effects were reported in some healthy elderly individuals. Most studies with B. monnierihave been preclinical evaluations of cellular mechanisms in the central nervous system and further translational clinical research needs to be performed to evaluate the safety and efficacy of the plant.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"2004 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89523436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.37360/blacpma.22.21.3.17
Dayvison Rhuan Vasco-dos-Santos, Jessica Vieira dos Santos, María José Gomes de Andrade, Lidiane Nunes Lima, Wbaneide Martins de Andrade, E. S. Nunes, A. Dias-Lima, M. Vannier-Santos
Indigenous knowledge is one of the most notable traditional sources about plants used to treat diseases. Thus, the aim of this study was to describe the botanical features and to investigate the pharmacological properties of plants used by the Kantaruré-Batida community to treat intestinal parasitosis. Botanical characterization was performed based on integrative review and on access to ‘Flora do Brasil’ platform, whereas plants’ pharmacological properties were investigated through systematic review. Among the 21 ethnospecies used, 48% were described as having activity against intestinal parasites. Although 52% had no such activity described, other properties can account for their use, that indicates that further studies are required. Therefore, this review reinforces the importance of valuing indigenous knowledge as tool to guide antiparasitic agent trials.
土著知识是关于用于治疗疾病的植物的最著名的传统资源之一。因此，本研究的目的是描述kantarur - batida群落用于治疗肠道寄生虫病的植物的植物学特征和药理特性。植物学特征是基于综合评价和“Flora do Brasil”平台进行的，而植物的药理学特性是通过系统评价来研究的。在使用的21种人种中，48%被描述为对肠道寄生虫有活性。虽然52%没有描述这种活性，但其他特性可以解释它们的用途，这表明需要进一步的研究。因此，本综述强调了重视本土知识作为指导抗寄生虫药物试验工具的重要性。
{"title":"Plants and intestinal parasitosis: a review on ethnopharmacological use by the Kantaruré-Batida indigenous community of Brazil","authors":"Dayvison Rhuan Vasco-dos-Santos, Jessica Vieira dos Santos, María José Gomes de Andrade, Lidiane Nunes Lima, Wbaneide Martins de Andrade, E. S. Nunes, A. Dias-Lima, M. Vannier-Santos","doi":"10.37360/blacpma.22.21.3.17","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.3.17","url":null,"abstract":"Indigenous knowledge is one of the most notable traditional sources about plants used to treat diseases. Thus, the aim of this study was to describe the botanical features and to investigate the pharmacological properties of plants used by the Kantaruré-Batida community to treat intestinal parasitosis. Botanical characterization was performed based on integrative review and on access to ‘Flora do Brasil’ platform, whereas plants’ pharmacological properties were investigated through systematic review. Among the 21 ethnospecies used, 48% were described as having activity against intestinal parasites. Although 52% had no such activity described, other properties can account for their use, that indicates that further studies are required. Therefore, this review reinforces the importance of valuing indigenous knowledge as tool to guide antiparasitic agent trials.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"46 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90773973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.37360/blacpma.22.21.1.07
Sharareh Shamloo, Sayeh Jafari Marandi, G. Tajadod, A. Majd, R. Rahimi
Cota tinctoria is a medicinal plant which has been used for management of cancer in folk medicine of various regions. The aim of present study is to investigate cytotoxic activity of different concentrations of hydroalcoholic extract of C. tinctoria flowers on gastric (AGS) and liver (Hep-G2) cancer cell lines as well as Human Natural GUM fibroblast (HUGU) cells. Cell mortality rates were examined after 24, 48 and 72 h incubations using the MTT assay. IC50 of extract on AGS cells after 24, 48 and 72h was 1.46, 1.29 and 1.14 µg/mL respectively. The extract demonstrated IC50 of 5.15, 3.92 and 2.89 µg/mL on Hep-G2 cells after 24, 48 and 72 h respectively. No cytotoxic effect was detected on HUGU (Human Natural GUM fibroblast) cells. C. tinctoria seems to have a promising potential to be considered as a source for anticancer drug discovery. However, more experimental and clinical studies are required.
{"title":"Cytotoxic effect of hydroalcoholic extract of Cota tinctoria (L.) J.Gay on AGS and Hep-G2 cancer cell lines","authors":"Sharareh Shamloo, Sayeh Jafari Marandi, G. Tajadod, A. Majd, R. Rahimi","doi":"10.37360/blacpma.22.21.1.07","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.1.07","url":null,"abstract":"Cota tinctoria is a medicinal plant which has been used for management of cancer in folk medicine of various regions. The aim of present study is to investigate cytotoxic activity of different concentrations of hydroalcoholic extract of C. tinctoria flowers on gastric (AGS) and liver (Hep-G2) cancer cell lines as well as Human Natural GUM fibroblast (HUGU) cells. Cell mortality rates were examined after 24, 48 and 72 h incubations using the MTT assay. IC50 of extract on AGS cells after 24, 48 and 72h was 1.46, 1.29 and 1.14 µg/mL respectively. The extract demonstrated IC50 of 5.15, 3.92 and 2.89 µg/mL on Hep-G2 cells after 24, 48 and 72 h respectively. No cytotoxic effect was detected on HUGU (Human Natural GUM fibroblast) cells. C. tinctoria seems to have a promising potential to be considered as a source for anticancer drug discovery. However, more experimental and clinical studies are required.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"2 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85414144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.37360/blacpma.22.21.1.02
A. M. Mesa-Vanegas, E. J. Naranjo-Gomez, Felipe Cardona, Lucia Atehortua-Garces, S. Blair-Trujillo
Solanum nudum Dunal (Solanaceae) is most commonly known and used by the population of the colombian Pacific coast as an antimalarial treatment. This article study into optimization and quantitative analysis of compounds steroidal over time of development of this species when grown in vitro and wild. A new steroidal compound named SN6 was elucidated by NMR and a new method of quantification of seven steroidal compounds (Diosgenone DONA and six steroids SNs) using HPLC-DAD-MS in extracts of cultures in vitro and wild was investigated. Biology activity of extracts was found to a range of antiplasmodial activity in FCB2 and NF-54 with inhibitory concentration (IC50) between (17.04 -100 μg/mL) and cytotoxicity in U-937 of CC50 (7.18 -104.7 μg/mL). This method creates the basis for the detection of seven sterols antiplasmodial present in extracts from S. nudum plant as a quality parameter in the control and expression of phytochemicals.
{"title":"Quantitative standardization of pharmacologically active components from antiplasmodial plant Solanum nudum Dunal (wild and in vitro)","authors":"A. M. Mesa-Vanegas, E. J. Naranjo-Gomez, Felipe Cardona, Lucia Atehortua-Garces, S. Blair-Trujillo","doi":"10.37360/blacpma.22.21.1.02","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.1.02","url":null,"abstract":"Solanum nudum Dunal (Solanaceae) is most commonly known and used by the population of the colombian Pacific coast as an antimalarial treatment. This article study into optimization and quantitative analysis of compounds steroidal over time of development of this species when grown in vitro and wild. A new steroidal compound named SN6 was elucidated by NMR and a new method of quantification of seven steroidal compounds (Diosgenone DONA and six steroids SNs) using HPLC-DAD-MS in extracts of cultures in vitro and wild was investigated. Biology activity of extracts was found to a range of antiplasmodial activity in FCB2 and NF-54 with inhibitory concentration (IC50) between (17.04 -100 μg/mL) and cytotoxicity in U-937 of CC50 (7.18 -104.7 μg/mL). This method creates the basis for the detection of seven sterols antiplasmodial present in extracts from S. nudum plant as a quality parameter in the control and expression of phytochemicals.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"5 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79524587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.37360/blacpma.22.21.4.28
Ronald Eduarte Saltos, N. Bec, Melisa Salinas Rivera, Jorge Ramirez Robles, C. Larroque, Chabaco Armijos
This article describes the chemical composition, physical properties and acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activity of stem-distilled essential oil (EO) from Bursera graveolenswood chips, Burseraceae. The plant material was acquired in Quimis (Bosque de Sancán), city of Jipijapa in the province of Manabí, coastal region of Ecuador. Thirty-six components were identified by CG-MS, which represented 98.54% of the volatile oil. The main components were limonene (68.52%) and mentofuran (20.37%). The hydrocarbon monoterpenes constituted the most abundant fractions. The average yield of the EOwas 1.26%. Regarding the physical properties of EO, the following values were obtained: relative density (1,029 g/mL), refractive index (1,477) and specific rotation (+4,567). The EOpresented IC50inhibition values of 47.2 and 51.9 μg/mL for the enzymes AChE and BuChE, respectively.
本文研究了刺科刺叶木片茎蒸馏精油的化学成分、物理性质及乙酰胆碱酯酶和丁基胆碱酯酶活性。该植物材料是在厄瓜多尔沿海地区Manabí省Jipijapa市Quimis (Bosque de Sancán)获得的。gc - ms共鉴定出36个组分，占挥发油总含量的98.54%。主要成分为柠檬烯(68.52%)和门托呋喃(20.37%)。烃类单萜是最丰富的组分。平均收益率为1.26%。关于EO的物理性质，得到了以下值:相对密度(1,029 g/mL)，折射率(1,477)和比旋转(+4,567)。对AChE和BuChE酶的ic50抑制值分别为47.2和51.9 μg/mL。
{"title":"Chemical composition and AChE-BuChE activities of the essential oil of palo santo Bursera graveolens(Kunth) Triana & Planch from Jipijapa, Ecuador","authors":"Ronald Eduarte Saltos, N. Bec, Melisa Salinas Rivera, Jorge Ramirez Robles, C. Larroque, Chabaco Armijos","doi":"10.37360/blacpma.22.21.4.28","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.4.28","url":null,"abstract":"This article describes the chemical composition, physical properties and acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activity of stem-distilled essential oil (EO) from Bursera graveolenswood chips, Burseraceae. The plant material was acquired in Quimis (Bosque de Sancán), city of Jipijapa in the province of Manabí, coastal region of Ecuador. Thirty-six components were identified by CG-MS, which represented 98.54% of the volatile oil. The main components were limonene (68.52%) and mentofuran (20.37%). The hydrocarbon monoterpenes constituted the most abundant fractions. The average yield of the EOwas 1.26%. Regarding the physical properties of EO, the following values were obtained: relative density (1,029 g/mL), refractive index (1,477) and specific rotation (+4,567). The EOpresented IC50inhibition values of 47.2 and 51.9 μg/mL for the enzymes AChE and BuChE, respectively.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"2 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83711400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.37360/blacpma.22.21.4.27
Ayse Usanmaz Bozhûyûk, S. Kordali, A. Gûnes, E. Beyzi, M. Turan, N. Ersoy
Aromatic and medicinal plants are of great importance to determine the contents of the active compounds of plant origin and to evaluate them depending on variety and climate factors in order to determine the phenolic, antioxidant enzyme activity, vitamin contents in species belonging to the Lamiaceae family. Examination of the characteristics of different species, the highest peroxidase (POD) enzyme activity, ascorbate peroxidase (AxPOD), total antioxidant (TA), malondialdehyte (MDA), caffeic acids (CA), vitamin C contents,and chloric acid (ChA) were obtained in the M. longifoliaspecies. The highest vitamin E and catalase (CAT) were determined in the S. hortensisspecies but the highest total phenolic (TP), superoxide dismutase (SOD) enzyme, hydrogen peroxide (H2O2) and chlorogenic acid (ChgA) were determined in the S. spicigeraspecies. As a result of PCA analysis, it can be said that Mentha longifolia(L.) Hudson and Satureja spicigeraspecies have significant value in terms of biochemical and phenolic content.
{"title":"Variation in phenolic, antioxidant and vitamin amounts among some medicinal plants and investigation by PCA analysis: Lamiaceae family","authors":"Ayse Usanmaz Bozhûyûk, S. Kordali, A. Gûnes, E. Beyzi, M. Turan, N. Ersoy","doi":"10.37360/blacpma.22.21.4.27","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.4.27","url":null,"abstract":"Aromatic and medicinal plants are of great importance to determine the contents of the active compounds of plant origin and to evaluate them depending on variety and climate factors in order to determine the phenolic, antioxidant enzyme activity, vitamin contents in species belonging to the Lamiaceae family. Examination of the characteristics of different species, the highest peroxidase (POD) enzyme activity, ascorbate peroxidase (AxPOD), total antioxidant (TA), malondialdehyte (MDA), caffeic acids (CA), vitamin C contents,and chloric acid (ChA) were obtained in the M. longifoliaspecies. The highest vitamin E and catalase (CAT) were determined in the S. hortensisspecies but the highest total phenolic (TP), superoxide dismutase (SOD) enzyme, hydrogen peroxide (H2O2) and chlorogenic acid (ChgA) were determined in the S. spicigeraspecies. As a result of PCA analysis, it can be said that Mentha longifolia(L.) Hudson and Satureja spicigeraspecies have significant value in terms of biochemical and phenolic content.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"61 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88165878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-30DOI: 10.37360/blacpma.21.20.4.26
Jose Hurtado-Huarcaya, Roxana Castañeda, J. Albán-Castillo
The aim of this research was conducted an ethnobotanical study of wild asteraceas for medicinal use in two Andean communities of southern Peru, located in Quinua (Ayacucho) and Lircay (Huancavelica) districts. Samples of Asteraceae family were collected and semistructured interviews were conducted to 191 informants (105 in Quinua and 86 in Lircay). Likewise, the cultural importance of each of the species was calculated. 28 genera and 44 species of medicinal wild asteraceae are registered in both communities; 33 species in Quinua and 35 in Lircay. All the species were classified within 18 medicinal subcategories, being the affections of the digestive and genitourinary system which presented the highest number of species and use reports. The Asteraceae of greater cultural importance for both communities is Ambrosia arborescens “marko”. The main conclusión is that communities studied still maintain the medicinal use of asteraceas until today.
本研究的目的是对秘鲁南部两个安第斯社区的药用野生菊科植物进行民族植物学研究，这两个社区位于Quinua (Ayacucho)和Lircay(万卡维利卡)地区。收集了菊科植物样本，对191名被调查者进行了半结构化访谈，其中奎努瓦105人，莱科86人。同样，计算了每个物种的文化重要性。两群落共有药用野星科植物28属44种;在奎奴亚有33种，在波多黎各有35种。所有种均归为18个药用亚类，以消化系统和泌尿生殖系统的作用种类最多，使用报道最多。对这两个群落具有更大文化重要性的菊科是Ambrosia arborescens " marko "。主要的conclusión是所研究的社区直到今天仍然保留了asteracea的药用用途。
{"title":"Medicinal Asteraceas in two Andean communities in southern Peru: Quinua (Ayacucho) and Lircay (Huancavelica)","authors":"Jose Hurtado-Huarcaya, Roxana Castañeda, J. Albán-Castillo","doi":"10.37360/blacpma.21.20.4.26","DOIUrl":"https://doi.org/10.37360/blacpma.21.20.4.26","url":null,"abstract":"The aim of this research was conducted an ethnobotanical study of wild asteraceas for medicinal use in two Andean communities of southern Peru, located in Quinua (Ayacucho) and Lircay (Huancavelica) districts. Samples of Asteraceae family were collected and semistructured interviews were conducted to 191 informants (105 in Quinua and 86 in Lircay). Likewise, the cultural importance of each of the species was calculated. 28 genera and 44 species of medicinal wild asteraceae are registered in both communities; 33 species in Quinua and 35 in Lircay. All the species were classified within 18 medicinal subcategories, being the affections of the digestive and genitourinary system which presented the highest number of species and use reports. The Asteraceae of greater cultural importance for both communities is Ambrosia arborescens “marko”. The main conclusión is that communities studied still maintain the medicinal use of asteraceas until today.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"1 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84412012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-30DOI: 10.37360/BLACPMA.21.20.3.20
Hyrla Grazielle Silva de Araujo Couto, Ana Andrea Teixeira Barbosa, D. A. C. Nizio, P. Nogueira, M. F. Arrigoni-Blank, J. Pinto, M. F. Alves, V. S. Pinto, A. Blank
The aim of this study was to undertake a screening experiment on essential oils (EO) of Myrcia lundiana, Ocimum basilicum and Lippia alba against six food-spoiling pathogenic bacteria. Seventy-two (72) samples were initially analyzed for antimicrobial activity based on the agar diffusion test. The minimum inhibitory (MIC) and bactericidal (MBC) concentrations were determined for the 12 samples which showed greatest antimicrobial potential in this stage. Two samples of L. alba, three samples of M. lundiana and seven samples of O. basilicum showed a MIC of 0.12-125 μL/mL for the six tested bacteria. Of these, the EO of O. basilicum cultivar Maria Bonita stood out with the lowest MIC and MBC. Thus, a mixture simulating this essential oil was prepared from commercial standards of the compounds (±)-linalool, geraniol and 1,8-cineole. Significantly higher MIC and MBC were detected in the simulation compared to the respective EO, suggesting a synergistic effectbetween compounds.
{"title":"Antibacterial activity of Lippia alba, Myrcia lundianaand Ocimum basilicumessential oils against six food-spoiling pathogenic microorganisms","authors":"Hyrla Grazielle Silva de Araujo Couto, Ana Andrea Teixeira Barbosa, D. A. C. Nizio, P. Nogueira, M. F. Arrigoni-Blank, J. Pinto, M. F. Alves, V. S. Pinto, A. Blank","doi":"10.37360/BLACPMA.21.20.3.20","DOIUrl":"https://doi.org/10.37360/BLACPMA.21.20.3.20","url":null,"abstract":"The aim of this study was to undertake a screening experiment on essential oils (EO) of Myrcia lundiana, Ocimum basilicum and Lippia alba against six food-spoiling pathogenic bacteria. Seventy-two (72) samples were initially analyzed for antimicrobial activity based on the agar diffusion test. The minimum inhibitory (MIC) and bactericidal (MBC) concentrations were determined for the 12 samples which showed greatest antimicrobial potential in this stage. Two samples of L. alba, three samples of M. lundiana and seven samples of O. basilicum showed a MIC of 0.12-125 μL/mL for the six tested bacteria. Of these, the EO of O. basilicum cultivar Maria Bonita stood out with the lowest MIC and MBC. Thus, a mixture simulating this essential oil was prepared from commercial standards of the compounds (±)-linalool, geraniol and 1,8-cineole. Significantly higher MIC and MBC were detected in the simulation compared to the respective EO, suggesting a synergistic effectbetween compounds.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"65 1","pages":"260-269"},"PeriodicalIF":0.7,"publicationDate":"2021-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81499125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-09DOI: 10.22541/AU.161796662.26625743/V1
Dan Liang, Yun Zhang, Z. Cao, Jingqin Chen, Zhuli Hou, L. Mao, Yuhan Pan, Ke Lu, Gang Fang
Abstract Background: To ascertain the estrogenic effect of Zhuang Medicated Thread Moxibustion (ZMTM) and explore its time-sensitive impact on estradiol in female perimenopausal rats. Methods: Female rats were randomized into four groups of 10 rats, each consisting of the control, model, ZMTM, and acupuncture groups. The perimenopausal syndrome was induced in the last three groups with a daily subcutaneous dose of 80 mg/kg of 4- vinylcyclohexene diepoxide for 15 days. Afterward, rats in the model and control groups were fed routinely, while rats in the ZMTM and acupuncture groups were treated with six ZMTM and acupuncture courses, respectively. The rats’ general condition and estradiol (E2) levels in the rats’ serum were assessed. Results: Following the six courses of treatment, the E2 level in the model group was significantly the lowest, while the regular group was the highest (P < 0.05). There was also a gradual increase in the E2 level of the ZMTM group compared to the model and acupuncture groups, such that after the 5th and 6th courses of treatment, their E2 level was significantly higher than the model and acupuncture groups (P < 0.05). The control group had a better condition than all other groups, while the ZMTM group was better than the model and acupuncture groups. Conclusion: ZMTM can improve perimenopausal induced rats’ estrogen level, and this effect becomes better with each further treatment course.
{"title":"Time-sensitive effects of Zhuang Medicated Thread Moxibustion on Estrogen Level in female perimenopausal Model Rats.","authors":"Dan Liang, Yun Zhang, Z. Cao, Jingqin Chen, Zhuli Hou, L. Mao, Yuhan Pan, Ke Lu, Gang Fang","doi":"10.22541/AU.161796662.26625743/V1","DOIUrl":"https://doi.org/10.22541/AU.161796662.26625743/V1","url":null,"abstract":"Abstract Background: To ascertain the estrogenic effect of Zhuang\u0000Medicated Thread Moxibustion (ZMTM) and explore its time-sensitive\u0000impact on estradiol in female perimenopausal rats. Methods: Female rats\u0000were randomized into four groups of 10 rats, each consisting of the\u0000control, model, ZMTM, and acupuncture groups. The perimenopausal\u0000syndrome was induced in the last three groups with a daily subcutaneous\u0000dose of 80 mg/kg of 4- vinylcyclohexene diepoxide for 15 days.\u0000Afterward, rats in the model and control groups were fed routinely,\u0000while rats in the ZMTM and acupuncture groups were treated with six ZMTM\u0000and acupuncture courses, respectively. The rats’ general condition and\u0000estradiol (E2) levels in the rats’ serum were assessed. Results:\u0000Following the six courses of treatment, the E2 level in the model group\u0000was significantly the lowest, while the regular group was the highest (P\u0000< 0.05). There was also a gradual increase in the E2 level of\u0000the ZMTM group compared to the model and acupuncture groups, such that\u0000after the 5th and 6th courses of treatment, their E2 level was\u0000significantly higher than the model and acupuncture groups (P\u0000< 0.05). The control group had a better condition than all\u0000other groups, while the ZMTM group was better than the model and\u0000acupuncture groups. Conclusion: ZMTM can improve perimenopausal induced\u0000rats’ estrogen level, and this effect becomes better with each further\u0000treatment course.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"97 5 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2021-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89541269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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