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Industrial Statistics in the Knowledge Economy 知识经济中的工业统计
IF 1.3 4区 数学 Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-05-15 DOI: 10.1002/asmb.70018
David Banks, Yue Li

Industrial statistics grew up in an era when manufacturing was the primary engine of commerce. Today, the driver is information technology. This paper discusses how statisticians need to adapt to contribute to this new business model, with particular emphasis upon computational advertising, autonomous vehicles, operations management, and large language models. Remarkably, many of our old tools are still relevant, even as the new problem space poses fresh research challenges for our employment and educational systems.

工业统计是在制造业是商业主要引擎的时代发展起来的。今天,驱动者是信息技术。本文讨论了统计学家需要如何适应这种新的商业模式,特别强调计算广告,自动驾驶汽车,运营管理和大型语言模型。值得注意的是,即使新的问题空间给我们的就业和教育系统带来了新的研究挑战,我们的许多旧工具仍然是相关的。
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引用次数: 0
A Multistate Markovian Model of the Economic Burden for Allergy Immunotherapy 变态反应免疫治疗经济负担的多态马尔可夫模型
IF 1.3 4区 数学 Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-05-15 DOI: 10.1002/asmb.70017
Massimo Bilancia, Gaetano Serviddio

The incidence of allergic rhinoconjunctivitis due to pollinosis is increasing in Western countries. The first-line therapy (No-AIT) typically involves the administration of antihistamines and corticosteroid sprays to manage symptoms. Immunotherapy represents an alternative treatment option, as it promotes desensitization to allergens. However, it is associated with significant costs. Currently, two types of allergen immunotherapy (AIT) are prescribed: subcutaneous immunotherapy and sublingual immunotherapy. This article compares these two therapeutic options with No-AIT. The comparison is conducted through a cost-effectiveness analysis (CEA), which evaluates health-related outcomes by estimating the incremental cost per unit of change in a composite outcome that combines morbidity and quality-of-life metrics. To perform the analysis, we developed a realistic multistate model describing the progression of a cohort of patients undergoing the three therapeutic approaches. The model was designed to be sufficiently flexible to account for treatment-related challenges commonly observed in real-world settings, which are often inadequately represented in randomized controlled trials. By employing a novel two-dimensional framework, we tracked the proportion of the cohort transitioning between health states during each cycle while simultaneously capturing the origin and destination of each transition. This approach enabled the integration of structural features that are typically overlooked, such as early treatment discontinuation, transition rewards, nonstationarities associated with the usual termination of immunotherapy after three years, and differential protection against severe complications (e.g., asthma) depending on whether immunotherapy was completed or not. Deterministic simulations were conducted using standard input parameters, supplemented by probabilistic simulations to generate CEACs for each of the three strategies. The results from our model indicate that AIT is not cost-effective unless the payer exhibits a moderately high willingness-to-pay. These findings have important implications for the pharmaceutical industry involved in the production of AIT drugs.

在西方国家,花粉症引起的变应性鼻结膜炎的发病率正在上升。一线治疗(No-AIT)通常包括使用抗组胺药和皮质类固醇喷雾来控制症状。免疫疗法是另一种治疗选择,因为它能促进对过敏原的脱敏。然而,它伴随着巨大的成本。目前,有两种类型的过敏原免疫治疗(AIT)处方:皮下免疫治疗和舌下免疫治疗。这篇文章比较了这两种治疗方案与无ait。比较是通过成本效益分析(CEA)进行的,该分析通过估算结合发病率和生活质量指标的复合结果中每单位变化的增量成本来评估与健康相关的结果。为了进行分析,我们开发了一个现实的多状态模型来描述一组接受三种治疗方法的患者的进展。该模型被设计得足够灵活,可以解释在现实环境中常见的与治疗相关的挑战,而这些挑战在随机对照试验中往往没有得到充分的体现。通过采用一种新的二维框架,我们跟踪了每个周期中在健康状态之间转换的队列比例,同时捕获了每个转换的起点和终点。这种方法能够整合通常被忽视的结构特征,如早期治疗终止、过渡奖励、通常在三年后终止免疫治疗相关的非平定性,以及取决于免疫治疗是否完成的对严重并发症(如哮喘)的不同保护。使用标准输入参数进行确定性模拟,并辅以概率模拟,为三种策略中的每种策略生成ceac。我们的模型的结果表明,除非付款人表现出中等高的支付意愿,否则在台投资并不具有成本效益。这些发现对参与AIT药物生产的制药行业具有重要意义。
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引用次数: 0
Soft-Clipping Autoregressive Models for Ordinal Time Series 有序时间序列的软裁剪自回归模型
IF 1.3 4区 数学 Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-05-05 DOI: 10.1002/asmb.70015
Christian H. Weiß, Osama Swidan

The linear autoregressive models are among the most popular models in the practice of time series analysis, which constitutes an incentive to adapt them to ordinal time series as well. Our starting point for modeling ordinal time series data is the latent variable approach to define a generalized linear model. This method, however, typically leads to a non-linear relationship between the past observations and the current conditional cumulative distribution function (cdf). To overcome this problem, we use the soft-clipping link to obtain an approximately linear model structure and propose a wide and flexible class of soft-clipping autoregressive (scAR) models. The constraints imposed on the model parameters allow us to identify relevant special cases of the scAR model family. We study the calculation of transition probabilities as well as approximate formulae for the CDF. Our proposals are illustrated by numerical examples and simulation experiments, where the performance of maximum likelihood estimation as well as model selection is analyzed. The novel model family is successfully applied to a real-world ordinal time series from finance.

线性自回归模型是时间序列分析实践中最常用的模型之一,这也促使人们将其应用于有序时间序列。我们对有序时间序列数据建模的起点是用潜变量方法定义广义线性模型。然而,这种方法通常会导致过去观测值与当前条件累积分布函数(cdf)之间的非线性关系。为了克服这一问题,我们使用软剪辑链接获得近似线性模型结构,并提出了一类广泛而灵活的软剪辑自回归(scAR)模型。施加在模型参数上的约束使我们能够识别scAR模型族的相关特殊情况。我们研究了转移概率的计算以及CDF的近似公式。通过数值算例和仿真实验说明了我们的建议,分析了最大似然估计和模型选择的性能。该模型族成功地应用于现实世界的金融有序时间序列。
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引用次数: 0
Integrated Optimization of Pricing, Maintenance Strategies, and Market Coverage: A Bargaining Model for Full-Service Contracts With Loss-Averse Participants 定价、维护策略和市场覆盖的综合优化:具有损失规避参与者的全服务合同的议价模型
IF 1.3 4区 数学 Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-04-29 DOI: 10.1002/asmb.70005
Ali Farrokhi-Sefat, Mohammad Sheikhalishahi, Ata Allah Taleizadeh

As industries increasingly outsource their Maintenance, Repair, and Overhaul (MRO) programs to third-party service providers, Original Equipment Manufacturers (OEMs) seek to expand their market share by providing comprehensive MRO packages along with the original products at a bundled price. This study introduces a bargaining model that jointly optimizes pricing, maintenance policies, and OEM's market coverage, considering participants' gain/loss behaviors within the Full-Service Product System (FSPS) contracts framework. We first provide closed-form analysis for various scenarios in a one-on-one bargaining negotiation, resulting in significant computational efficiency and insightful managerial implications. It also enables us to expand the problem to multiple contracts and develop an algorithm that simultaneously optimizes client density, profitability, pricing and MRO policies. The findings indicate that when players' profits fall short of their reference point, a more loss-averse approach results in increased personal profit and less favorable outcomes for the opponent. We further enrich our findings by conducting a sensitivity analysis of the parameters affecting the pricing, MRO policies, and market coverage.

随着越来越多的行业将维护、维修和大修(MRO)项目外包给第三方服务提供商,原始设备制造商(oem)试图通过以捆绑价格提供全面的MRO包和原始产品来扩大市场份额。本研究引入一个议价模型,在全服务产品系统(FSPS)契约框架下,考虑参与者的得失行为,共同优化定价、维护政策和OEM的市场覆盖。我们首先对一对一讨价还价谈判中的各种情况进行了封闭式分析,从而提高了计算效率和深刻的管理意义。它还使我们能够将问题扩展到多个合同,并开发一种算法,同时优化客户密度、盈利能力、定价和MRO政策。研究结果表明,当玩家的利润低于他们的参考点时,更厌恶损失的方法会导致个人利润增加,而对对手不利的结果。我们通过对影响定价、MRO政策和市场覆盖范围的参数进行敏感性分析,进一步丰富了我们的发现。
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引用次数: 0
Assessing Latent Risk Based on Joint Modelling of Multiple Health Insurance Outcomes of Mixed Types 基于混合类型多重健康保险结果联合建模的潜在风险评估
IF 1.3 4区 数学 Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-04-23 DOI: 10.1002/asmb.70012
Xingde Duan, Renjun Ma

Our research is motivated by an insurance study involving 788 insurance subscribers who made claims resulting from ischemic heart disease. Four different types of health services used by these subscribers as well as the corresponding total cost were observed for two years. Health care utilizations vary a lot even for subscribers of the same personal characteristics. The research question of primary interest is how to capture patient-specific latent risks beyond what can be explained by known personal characteristics. In this study, we characterize unobserved latent risks by random effects in our joint Tweedie mixed models for multiple health outcomes of mixed types. An optimal estimation of our model has been developed using the orthodox best linear unbiased predictors of random effects. Our approach is illustrated with the analysis of the health insurance study of 788 ischemic heart disease patients. Applying cluster analysis to the patient-specific latent risks predicted by our model, we were able to classify patients into a high risk group of 36 patients, a medium risk group of 256 patients and a low risk group of 496 patients. The finding is of important policy relevance since the losses suffered by a few are known to be spread over many in an insurance system. Grouping of patients and prioritization of specific groups based on subject-specific latent risks facilitates resource allocation and pricing.

我们的研究是受到一项保险研究的启发,该研究涉及788名因缺血性心脏病而索赔的保险订户。对这些用户使用的四种不同类型的保健服务以及相应的总费用进行了为期两年的观察。即使对于具有相同个人特征的订阅者,医疗保健的利用也有很大差异。最主要的研究问题是如何捕捉患者特有的潜在风险,而不是已知的个人特征所能解释的。在这项研究中,我们通过随机效应在我们的联合Tweedie混合模型中描述了未观察到的潜在风险,用于混合类型的多种健康结局。使用随机效应的正统最佳线性无偏预测因子对我们的模型进行了最优估计。通过对788例缺血性心脏病患者健康保险研究的分析,说明了我们的方法。通过对模型预测的患者特异性潜在风险进行聚类分析,我们可以将患者分为高风险组36例,中等风险组256例,低风险组496例。这一发现具有重要的政策意义,因为众所周知,少数人遭受的损失会在保险体系中蔓延到许多人身上。根据特定主题的潜在风险对患者进行分组并对特定组进行优先排序,有助于资源分配和定价。
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引用次数: 0
Designing Accelerated Degradation Tests Based on Wiener Process With a Positive Relation Between the Drift Rate and the Volatility 基于漂移率与挥发性呈正相关的Wiener过程的加速退化试验设计
IF 1.3 4区 数学 Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-04-09 DOI: 10.1002/asmb.70010
Daojiang He, Lei He, Jinming Ren

In this paper, we study the optimal design problem for constant-stress accelerated degradation tests using a new class of Wiener processes that effectively capture the positive relation between the drift rate and the volatility. Under the D$$ D $$-, A$$ A $$-, and c$$ c $$-optimality criteria, both the test stress levels and the allocation of test units at each stress level are explicitly determined. We provide a numerical example using carbon-film resistor data to validate our theoretical findings and perform a simulation study to highlight the advantages of our proposed designs. The numerical results suggest that the proposed designs outperform existing designs in terms of estimation accuracy.

在本文中,我们研究了恒定应力加速降解试验的优化设计问题,采用了一类新的维纳过程,有效地捕捉了漂移率和波动率之间的正相关关系。在 D $$ D $$ -、A $$ A $$ - 和 c $$ c $$ - 的最优标准下,试验应力水平和每个应力水平的试验单元分配都是明确确定的。我们提供了一个使用碳膜电阻器数据的数值示例,以验证我们的理论发现,并进行了模拟研究,以突出我们建议的设计的优势。数值结果表明,建议的设计在估计精度方面优于现有设计。
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引用次数: 0
Incorporating Asymmetric Loss for Real Estate Prediction With Area-Level Spatial Data 基于区域级空间数据的非对称损失房地产预测
IF 1.3 4区 数学 Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-04-02 DOI: 10.1002/asmb.70009
Vaidehi Dixit, Scott H. Holan, Christopher K. Wikle

We investigate two asymmetric loss functions, namely linear exponential (LINEX) loss and power divergence loss for optimal spatial prediction with area-level data. With our motivation arising from the real estate industry, namely in real estate valuation, we use the Zillow Home Value Index (ZHVI) for county-level values to show the change in prediction when the loss is different (asymmetric) from a traditional squared error loss (symmetric) function. Additionally, we discuss the importance of choosing the asymmetry parameter and propose a solution to this choice for a general asymmetric loss function. Since the focus is on area-level data predictions, we propose the methodology in the context of conditionally autoregressive (CAR) models. We conclude that the choice of the loss functions for spatial area-level predictions can play a crucial role and is heavily driven by the choice of parameters in the respective loss.

我们研究了两种非对称损失函数,即线性指数(LINEX)损失和幂发散损失,用于区域级数据的最优空间预测。我们的研究动机来自于房地产行业,即房地产估价,我们使用 Zillow 房屋价值指数(ZHVI)的县级数值来展示当损失与传统的平方误差损失(对称)函数不同(非对称)时预测的变化。此外,我们还讨论了选择非对称参数的重要性,并提出了针对一般非对称损失函数选择非对称参数的解决方案。由于重点是地区级数据预测,我们在条件自回归(CAR)模型的背景下提出了这一方法。我们的结论是,对于空间区域级预测,损失函数的选择可以起到至关重要的作用,并且在很大程度上受各自损失参数选择的影响。
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引用次数: 0
Hazard Rate Order Between Parallel Systems With Multiple Types of Scaled Components 具有多种比例元件的并联系统间的危险率顺序
IF 1.3 4区 数学 Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-03-27 DOI: 10.1002/asmb.70008
Khaled Masoumifard, Abedin Haidari, Nuria Torrado

This study delves into the comparison of two parallel systems, each composed of multiple component types following the scale models with a shared baseline distribution. Under some assumptions imposed on the baseline distribution, it is shown that a restricted version of the p$$ p $$-larger order between the scale parameter vectors implies the hazard rate order between the system lifetimes, provided that the allocation vectors of the two systems are the same. Additionally, we explore scenarios where one system embodies heterogeneous scale parameters, whereas the other adopts homogeneous ones, examining the hazard rate order between their lifetimes. For the case when the scale vectors of the two systems are the same, it is shown under some assumptions on the baseline distribution that the weak supermajorization order between the allocation vectors results in the reversed hazard rate order between the system lifetimes. Under more restrictions on the allocation vectors, an extension of this result to the likelihood ratio order is also established. Our discussion also highlights the fulfillment of these assumptions by well-known lifetime distributions such as Feller-Pareto, generalized gamma, power-generalized Weibull, exponentiated Weibull, and half-normal distributions. The findings of this work contribute to addressing gaps in the understanding of stochastic orderings between parallel systems and further refine prior research in this domain. Furthermore, the results provide a foundation for practical applications, such as optimizing resource allocation and reliability assessment in engineering and operational contexts.

本研究深入研究了两个并行系统的比较,每个系统由多个组件类型组成,遵循具有共享基线分布的比例模型。在对基线分布施加一些假设的情况下,如果两个系统的分配向量相同,则尺度参数向量之间的p $$ p $$ -较大阶数的限制版本意味着系统生命周期之间的危险率阶数。此外,我们探讨了一个系统包含异质尺度参数,而另一个系统采用同质尺度参数的情况,检查了它们的生命周期之间的危险率顺序。对于两个系统的尺度向量相同的情况,在基线分布的某些假设下,分配向量之间的弱超多数顺序导致系统生命周期之间的危险率顺序相反。在对分配向量有更多限制的情况下,将这一结果推广到似然比阶。我们的讨论还强调了众所周知的寿命分布(如Feller-Pareto、广义伽马、幂广义威布尔、指数威布尔和半正态分布)对这些假设的满足。这项工作的发现有助于解决并行系统之间随机排序的理解差距,并进一步完善该领域的先前研究。此外,研究结果为工程和操作环境中的资源优化分配和可靠性评估等实际应用提供了基础。
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引用次数: 0
No-Arbitrage Valuation of Contingent Claims Depending on an Untradeable Asset 基于不可交易资产的或有债权的无套利估值
IF 1.3 4区 数学 Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-03-23 DOI: 10.1002/asmb.70007
Erindi Allaj

We consider an incomplete market situation with the presence of an untradeable asset and several tradeable assets. By an untradeable asset we mean an asset that cannot be traded on a public market. Typical examples of untradeable assets include real options and private credit/debt investments. We then exploit the relationship between the untradeable asset and tradeable assets to evaluate contingent claims depending on the untradeable asset. Under a multidimensional generalized Black–Scholes (GBS) framework, we study two different methods for pricing these kinds of contingent claims. The first is mean-variance hedging (MVH). The second is the method proposed in Jarrow (2023). We illustrate the two methods by applying them to two particular contingent claims: The option to defer and the spread option. No-arbitrage prices and admissible replicating trading strategies are derived. Lastly, we run simulations to test the performance of these replicating trading strategies.

我们考虑存在一项不可交易资产和若干项可交易资产的不完全市场情况。不可交易资产是指不能在公开市场上交易的资产。不可交易资产的典型例子包括实物期权和私人信贷/债务投资。然后,我们利用不可交易资产和可交易资产之间的关系来评估依赖于不可交易资产的或有债权。在多维广义Black-Scholes (GBS)框架下,研究了这类或有债权的两种不同定价方法。第一种是均值方差套期保值(MVH)。第二种是Jarrow(2023)提出的方法。我们通过将这两种方法应用于两个特定的或有债权来说明这两种方法:延期期权和价差期权。推导出无套利价格和允许复制交易策略。最后,我们运行模拟来测试这些复制交易策略的性能。
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引用次数: 0
Digital Twins: A Revolution in Modeling and Simulation 数字孪生:建模和仿真的革命
IF 1.3 4区 数学 Q3 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-03-13 DOI: 10.1002/asmb.70006
Jean-Michel Poggi, Murat Caner Testik
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引用次数: 0
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Applied Stochastic Models in Business and Industry
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