American Journal of Sports Medicine最新文献

Background: Currently, there is no uniform rehabilitation program concerning mobilization after a distal biceps tendon repair. A systematic review was conducted to investigate the effect of restrictions within the immediate postoperative period to evaluate clinical outcomes relative to mobilization after surgical repair of complete distal biceps tendon tears.

Hypothesis: Early mobilization will not have a significant difference on outcomes compared with delayed mobilization.

Study design: Meta-analysis; Level of evidence, 3.

Methods: The authors performed a systematic review in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines of studies reporting outcomes of the distal biceps tendon repair. The early mobilization cohort included studies with no restrictions beyond 2 weeks after surgery, and the delayed mobilization cohort included studies with continued restrictions beyond 2 weeks after surgery.

Results: A total of 26 studies with 1114 patients (643 in the delayed mobilization cohort and 471 in the early mobilization cohort) met the inclusion criteria, with a weighted mean patient age of 45.14 years (range, 18-76 years) and a mean follow-up of 27.9 months (range, 3-120 months). Meta-analysis at the 24-month follow-up found that range of motion (ROM) was not significantly different across early and delayed mobilization cohorts for flexion (mean, 137.38° vs 140.42°; P = .34) and extension (mean, 3.23° vs 1.5°; P = .91). Early mobilization was found to be significantly associated with less pronation (mean, 75.68° vs 83.18°; P = .0019) and supination (mean, 76.38° vs 83.93°; P = .0049). Analysis of patient-reported outcomes (PROs) found that Disabilities of the Arm, Shoulder and Hand scores (mean, 3.93 vs 4.21; P = .77) and Mayo Elbow Performance Score values (mean, 96.33 vs 97.11;P = .65) were not significantly different across cohorts. Failure analysis found a significant difference when comparing proportion (mean, 0.0006 vs 0.0185; P = .0029) but no difference when comparing incidence rate (mean, 0.0001 vs 0.0001; P = .647). Complication analysis found no statistical difference in proportion (mean, 0.2181 vs 0.1918; P = .7388) or incidence rate (mean, 0.0012 vs 0.008; P = .344).

Conclusion: These results suggest there may be no clinically significant difference in failure rates, complications, ROM, or PROs for early versus delayed mobilization after primary distal biceps tendon repair.

Background: The knee is the most commonly afflicted joint in osteoarthritis (OA). Injection of intra-articular of hyaluronic acid (IAHA) is a frequently used therapy for the management of knee OA with varying product characteristics.

Purpose: To describe and characterize the mechanism of action (MoA) of IAHA products concerning nociception, chondroprotection, and anti-inflammatory properties via a targeted literature review.

Study design: Systematic review; Level of evidence, 2.

Methods: We followed the standard methodologies for conducting and reporting targeted reviews as recommended by the Cochrane Handbook for Systematic Reviews of Interventions, adapted for conducting a targeted literature review. Relevant studies were identified by searching the Embase database using predefined search strategies via the Ovid platform. The results of the review were reported according to the PRISMA guidelines (Preferred Reporting Items for Systematic Reviews and Meta-analyses).

Results: A total of 182 studies were included in this targeted literature review. Of these, 107 reported chondroprotective action, 59 anti-inflammatory activity, 18 analgesic properties, 30 proteoglycan or glycosaminoglycan synthesis, 8 subchondral bone effects, 2 mechanical effects, and 1 other effects of IAHA. These MoAs were studied through diverse types of studies: in vitro biochemistry, animal physiological studies, or human physiological and clinical studies. The chondroprotective effect was the most studied MoA and showed an increase in anabolic biomarkers, such as collagen types II, IX, and XI, and a reduction in catabolic biomarkers, such as matrix metalloproteinases, which play a primary role in the downstream signaling pathways in OA and cartilage degradation in the synovial fluid. IAHA was widely reported by studies to reduce soluble inflammatory mediators, such as interleukins 1β and 6 and tumor necrosis factor α, thereby decreasing the production of degradative enzymes (eg, matrix metalloproteinases, aggrecanases). IAHA was also reported to enhance the synthesis of intrinsic proteoglycan (eg, aggrecan) and glycosaminoglycans, thus delaying the progression of OA. IAHA also reported improvement in the mechanical function of the knee by increasing the viscosity of the synovial fluid, reducing the coefficient of friction, and improving its lubrication. Overall, a significant decrease in knee pain was observed after IAHA treatments.

Conclusion: Preclinical and clinical studies established evidence for varied MoAs by which IAHA preparations may produce a desired effect in patients with knee OA.

Background: Countermovement jump (CMJ) analyses can predict ulnar collateral ligament (UCL) injuries in professional baseball pitchers, yet a biomechanical determinant linking CMJ analytics to UCL sprains is unknown.

Purpose/hypothesis: The purpose of this study was to evaluate CMJ parameters in collegiate pitchers with high and low elbow varus torque (EVT) and investigate multilinear regression relationships between CMJ and EVT kinetics. It was hypothesized that pitchers with greater EVT would have greater CMJ measures, and CMJ kinetics would explain the variance in EVT kinetics.

Study design: Descriptive laboratory study.

Methods: Analyses of 19 Division I collegiate baseball pitchers (age, 19.9 ± 1.5 years; body height, 1.87 ± 0.08 m; body mass, 90.0 ± 13.4 kg) were performed with integrated ball release speed, 3-dimensional motion capture, and ground reaction force (GRF) technology. A 1-way between-participant analysis of variance was used to compare CMJ and ball velocity metrics, while Pearson correlations (r) were used to evaluate the association between EVT and CMJ kinetic variables. An alpha level of .05 indicated statistical significance for all tests that included effect size calculations (η²) for mean differences.

Results: The EVT rate of torque development (EVTRTD) was significantly greater in pitchers with a higher EVT (high EVT: 605 ± 74 vs low EVT: 353 ± 103 N·m·s^-1; P < .001; η² = 0.41). CMJ data were similar between groups, yet correlation models indicated that changes in peak CMJ GRF (r = 0.60, P < .001) and power (r = 0.53, P < .05) can explain variance in EVTRTD.

Conclusion: Compared with absolute EVT, CMJ kinetics were more associated with the rate of EVT in collegiate pitchers.

Clinical relevance: Therefore, as it relates to injury surveillance, identifying pitchers who display increases in peak GRF, concentric impulse, and peak CMJ power may provide early detection in protecting athletes from elbow valgus overload.

Background: An anterior cruciate ligament (ACL) injury is a severe condition that may affect the career of young athletes. There is limited evidence on the rate and level of return to sport (RTS) after pediatric and adolescent ACL reconstruction.

Purpose: To evaluate clinical outcomes, the level and rate of RTS, and predictive factors for RTS after pediatric and adolescent ACL reconstruction.

Study design: Cohort study; Level of evidence, 3.

Methods: Patients aged between 10 and 18 years at the time of primary ACL reconstruction were screened for eligibility. Based on age at the time of ACL reconstruction, patients were divided into the pediatric (female: 11-13 years; male: 11-15 years) and adolescent (female: 14-18 years; male: 16-18 years) groups. Patient-specific, injury-related, and treatment-specific data, as well as subscores of the Knee injury and Osteoarthritis Outcome Score (KOOS) at baseline and 1-, 2-, 5-, and 10-year follow-up, were obtained. A survey consisting of 3 patient-specific and 30 knee-related questions was developed by experts in the management of ACL injuries and was sent to all patients to determine sport-specific variables and RTS rates.

Results: Overall, 1392 patients (total response rate: 24%) were included in this study. There were 81 pediatric patients (mean age at ACL reconstruction, 13.7 ± 1.4 years) and 1311 adolescent patients (mean age at ACL reconstruction, 16.5 ± 1.2 years). Significant improvements in KOOS subscores were observed after both pediatric and adolescent ACL reconstruction at each follow-up time point. After ACL reconstruction, 74% of pediatric patients and 68% of adolescent patients returned to their previous type of sport (P = .23). Moreover, 31% of pediatric patients and 23% of adolescent patients became elite athletes (highest national level of junior sport or higher) after ACL reconstruction (P = .13). A cartilage injury at the time of ACL reconstruction was found to lower the odds of pediatric and adolescent patients returning to their previous type of sport (odds ratio, 0.60; P = .001). A second ACL injury occurred in 25% and 31% of pediatric and adolescent patients, respectively (P = .29).

Conclusion: Long-lasting clinical improvements and high RTS rates can be expected after pediatric and adolescent ACL reconstruction. Moreover, young athletes still have the chance to compete at an elite level of sport after ACL reconstruction.

Background: Accurate femoral tunnel positioning is essential for successful anterior cruciate ligament (ACL) reconstruction. Tunnel malposition can happen due to limited arthroscopic visibility as well as anatomic variance. The use of customized patient-specific guides can optimize surgical planning and enhance accuracy.

Purpose: To compare femoral tunnel positioning in 3-dimensional (3D)-assisted ACL reconstruction versus conventional surgery.

Study design: Systematic review and meta-analysis; Level of evidence, 3.

Methods: This systematic review and meta-analysis was performed in line with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines with a search of the following databases: MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials. All randomized controlled trials (RCTs) and observational studies comparing the 2 interventions were included. Primary outcomes included tunnel positioning time (minutes) and accuracy rates (%). Secondary outcomes were Lysholm and International Knee Documentation Committee (IKDC) functional scores. Random effects modeling was used for analysis.

Results: Four RCTs and 1 retrospective study were included, enrolling a total of 299 patients. The 3D group had significantly shorter tunnel positioning times (mean difference, -2.80; 95% CI, -4.13 to -1.46; P < .0001) with significantly greater tunnel positioning accuracy (odds ratio, 4.62; 95% CI, 1.02 to 20.89; P = .05). No significant difference was noted in postoperative functional scores, including Lysholm and IKDC scores (P > .05).

Conclusion: The use of 3D guides helps reduce tunnel positioning time and increases tunnel positioning accuracy with comparable postoperative functional outcomes.

Background: High tibial osteotomy (HTO) is usually performed in patients older than 50 years with medial knee osteoarthritis. However, little is known about return-to-sport (RTS) and return-to-work (RTW) rates when HTO is performed in younger patients. Moreover, the risk factors for RTS and the impact of kinesiophobia on RTS have been poorly investigated.

Purpose: To assess RTS and RTW rates, risk factors for RTS, complications, and activity levels at long-term follow-up in young and active patients after isolated HTO.

Study design: Case series; Level of evidence, 4.

Methods: Consecutive HTO procedures performed at a single institution with a minimum 2-year follow-up were screened. Data were collected regarding clinical scores (Lysholm score, visual analog scale for pain, Tampa Scale for Kinesiophobia, Subjective Patient Outcome for Return to Sports score, Tegner activity score, Likert scale), RTS and RTW rates, type of sport, and impact activity level. Multivariate regression analysis evaluated the effect of sex, age, body mass index, Tegner score, and Tampa score on RTS. Differences were considered statistically significant if P < .05.

Results: A total of 60 patients with a mean age at the time of surgery of 28.9 ± 7.5 years were included at a mean follow-up of 8.8 ± 3.8 years. There were 4 (6.7%) major complications. The overall RTS rate was 86.7%, and 68.3% of patients were still participating in sports at the final follow-up (mean, 3.7 ± 2.1 h/wk). Additionally, 34.6% returned to the same sport level, 21.2% improved their status, and 44.2% decreased their sport level. Moreover, patients playing soccer had a lower RTS rate compared with the rest of the patients (72.7% vs 94.7%, respectively; P = .04). The overall RTW rate was 100.0%, with a mean time to RTW of 5.9 ± 6.2 months. The Tampa score was the only predictor of absolute RTS (P = .015; coefficient = -0.13).

Conclusion: HTO performed in a young and active population resulted in high RTS rates and continuous sport participation even up to 9 years after surgery. Interestingly, the Tampa score was the only predictive factor for a reduced RTS rate. Finally, soccer participation was associated with a lower RTS rate compared with other sports.

Background: Chaotic sporting environments require the performance of concurrent cognitive and motor tasks. A reduced capacity for either or both of the tasks when performed concurrently is known as cognitive-motor interference (CMi) and is believed to increase the injury risk. A greater susceptibility to CMi after a rupture of the anterior cruciate ligament (ACL) has been suggested to be caused by central nervous system adaptations, thus possibly contributing to high secondary ACL injury rates.

Purpose: To investigate whether patients after ACL reconstruction (ACLR) demonstrate greater CMi than noninjured controls when adding secondary cognitive tasks to the drop vertical jump (DVJ) and explore the potential influence of sex on CMi.

Study design: Controlled laboratory study.

Methods: A total of 40 (50% male) sports-active patients who had undergone ACLR (mean, 24.9 ± 16.1 months after surgery) and 40 (50% male) sports-active noninjured controls performed DVJs with and without secondary cognitive tasks targeting short-term memory, attention, fast decision-making, and inhibitory control. Outcomes included a letter position recall task and 3 motor variables: (1) correct action (landing or landing with a subsequent vertical jump), (2) relative jump height (relative between DVJs), and (3) relative peak vertical ground-reaction force (relative between DVJs). Participants also completed isolated cognitive tests (CANTAB) included as covariates in multivariate analysis.

Results: Multivariate analysis of variance revealed that the ACLR group had greater CMi than the control group (P < .001), as manifested by more incorrect answers for the cognitive letter recall task (mean difference [MD], -13.3% [95% CI, -20.8% to -5.9%]; P < .001), more incorrect motor actions (MD, -7.5% [95% CI, -12.4% to -2.6%]; P = .003), and a reduced relative jump height (MD, -4.5% [95% CI, -7.9% to -1.2%]; P = .010). No difference in relative peak vertical ground-reaction force was found (MD, 2.8% [95% CI, -7.7% to 13.3%]; P = .59). Isolated cognitive outcomes did not affect these results, and there were no significant differences between male and female participants.

Conclusion: Patients after ACLR showed greater CMi than noninjured controls, which was unrelated to isolated cognitive outcomes, thus indicating aberrant neurocognitive function.

Clinical relevance: Clinicians should consider cognitive and dual-task training and screening during ACL rehabilitation to better prepare patients for chaotic and uncontrolled sporting environments in which dual tasking is prevalent. Such interventions may help to reduce the risk of secondary ACL injuries.

Background: The number of medial ulnar collateral ligament (MUCL) reconstructions is increasing. The epidemiology surrounding revision MUCL reconstructions in professional baseball players has not been well defined.

Purpose/hypothesis: The purpose was to report the epidemiology of revision MUCL reconstruction in professional baseball players. The authors hypothesized that the number of revision MUCL reconstructions has increased over time and that the rate of return to sport at the same level of play is <70%.

Study design: Case series; Level of evidence, 4.

Methods: All professional baseball pitchers who underwent revision MUCL reconstruction between 2010 and 2023 were identified using the Major League Baseball Health and Injury Tracking System. Rates of return to play, time to return to play, and return to same level of play were recorded and analyzed for pitchers with a minimum follow-up of 2 years. Surgical variables, including technique and graft choice, were also recorded.

Results: Overall 191 pitchers (mean age, 26.0 years) underwent revision MUCL reconstruction. The mean time between primary and revision surgery was 1381 days (45 months). Of these players, 130 (68%) were Minor League Baseball pitchers. Hamstring tendon autograft was the most commonly used graft source (n = 90; 47%) when compared with palmaris longus autograft (n = 67; 35%). In terms of tunnel configuration, the modified Jobe and docking techniques were used in equal occurrence (n = 70; 37%). After revision MUCL reconstruction, only 72% of professional baseball pitchers were able to return to play at any level at a mean 556 days (18 months), and only 58% were able to return to the same level of play at a mean 604 days (20 months). The mean time between primary and revision MUCL reconstruction was 45 months (3.75 years).

Conclusion: Revision MUCL surgery continues to be a challenging problem, where the procedure is complex, rehabilitation timelines are prolonged, and outcomes are not always optimal. Accordingly, the authors recommend that these procedures be performed by surgeons with high levels of experience.