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Long-term Recurrence Rates After Isolated Arthroscopic Bankart Repair in Selected Patients Without Preoperative Bone Loss Versus Open Latarjet Procedure: A Matched-Pair Analysis. 选择术前无骨丢失的患者进行单独关节镜Bankart修复后的长期复发率与开放Latarjet手术:配对分析。
IF 4.2 1区 医学 Q1 ORTHOPEDICS Pub Date : 2025-01-22 DOI: 10.1177/03635465241309330
Clémentine Rieussec, Juan Enrique Cassinelli, Matias Hoffman, Clément Horteur, Johannes Barth

Background: Clinical studies have shown that the open Latarjet procedure (OLP) has lower recurrence rates than the isolated arthroscopic Bankart (IAB) procedure for recurrent anterior shoulder instability, but no long-term comparative studies exist for IAB in patients without bone loss.

Purpose/hypothesis: This study aimed to compare the outcomes of IAB in selected patients without bone loss versus OLP. The hypothesis was that OLP would be more successful in preventing recurrence, even in carefully selected patients for IAB.

Study design: Cohort study; Level of evidence 3.

Methods: An overall 774 patients who underwent surgical stabilization for recurrent anterior instability between January 2007 and December 2021 were analyzed. A total of 685 shoulders were followed up (89 patients were lost of follow-up: 11,4%), including 582 OLP, 45 IAB, and 58 other techniques (Trillat procedure, Arthroscopic Latarjet procedure, and revision Eden Hybinette procedure). The patients who underwent primary IAB were matched with patients who underwent OLP in a 1:1 ratio using propensity matching, resulting in 45 patients in each group. The main objective was to identify new episodes of instability, with a recurrence rate <5% considered acceptable. Kaplan-Meier analysis was used to evaluate patient survivorship, and logistic regression was performed to consider potential factors affecting recurrence rates. Data were collected on return-to-sport rate, Walch and Duplay score, visual analog scale score, and external rotation.

Results: The mean follow-up was 9 years and 3 months. A new episode of instability occurred in 2% of the OLP group and 20% of the IAB group (P = .04; odds ratio, 11; 95% CI, 1.91-63.4, Miettinen method). Regarding the rest of our analyses, there was no significant difference. Patients maintained good external rotation with low pain: 68° in the OLP group as compared with 72° in the IAB group (P = .325), with 1.2 out of 10 on the visual analog scale in the OLP group versus 1.5 in the IAB group (P = .433), respectively. Walch and Duplay score reached 79.9 in the OLP group and 78.9 in the IAB group (P = .496), and 89% of the OLP group returned to its previous sport level as compared with 73% of the IAB group (P = .104).

Conclusion: Patients who underwent an OLP had better long-term survivorship without recurrence when compared with those who underwent an IAB, even without bone loss. The odds of experiencing a new episode of instability recurrence was 11 times higher for patients who underwent IAB, with a mean follow-up of 9 years and 3 months.

背景:临床研究表明,开放性Latarjet手术(OLP)治疗复发性肩前路不稳的复发率低于孤立性关节镜Bankart手术(IAB),但没有长期比较IAB治疗无骨质丢失患者的研究。目的/假设:本研究旨在比较IAB在选择的无骨质流失患者和OLP患者中的结果。假设OLP在预防复发方面更成功,即使是在精心挑选的IAB患者中也是如此。研究设计:队列研究;证据等级3。方法:对2007年1月至2021年12月期间接受手术稳定治疗复发性前路不稳的774例患者进行分析。共随访685例肩部(89例失访:11.4%),包括582例OLP, 45例IAB和58例其他技术(Trillat手术,关节镜Latarjet手术和Eden Hybinette翻修手术)。采用倾向匹配法,将原发性IAB患者与OLP患者按1:1的比例进行匹配,每组45例。主要目的是确定不稳定的新发作,复发率结果:平均随访时间为9年零3个月。OLP组的2%和IAB组的20%出现新的不稳定发作(P = 0.04;优势比为11;95% CI, 1.91-63.4 (Miettinen方法)。至于我们其余的分析,没有显著差异。患者保持良好的外旋,疼痛度低:OLP组为68°,IAB组为72°(P = .325), OLP组视觉模拟评分为1.2(满分10分),IAB组为1.5 (P = .433)。OLP组和IAB组的Walch和Duplay评分分别达到79.9分和78.9分(P = .496), OLP组89%的人恢复到原来的运动水平,而IAB组的这一比例为73% (P = .104)。结论:与接受IAB的患者相比,接受OLP的患者即使没有骨质流失,也有更好的无复发长期生存。在平均9年零3个月的随访中,接受IAB治疗的患者出现不稳定复发的几率高出11倍。
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引用次数: 0
Regional Patellar Tendon Strain in the Short- and Long-term After ACL Reconstruction Using Bone-Patellar Tendon-Bone Autograft. 自体骨-髌腱-骨移植重建前交叉韧带后短期和长期的局部髌骨肌腱劳损。
IF 4.2 1区 医学 Q1 ORTHOPEDICS Pub Date : 2025-01-22 DOI: 10.1177/03635465241310152
João Luiz Quaglioti Durigan, Naoaki Ito, Rodrigo Scattone Silva, Karin Grävare Silbernagel

Background: Anterior cruciate ligament reconstruction (ACLR) often involves harvesting a bone-patellar tendon-bone (BPTB) autograft. How graft harvest affects tendon strain across the 3 distinct regions (medial, lateral, and central) is not known.

Purpose: To (1) quantify strain in the 3 regions of the patellar tendon during 60% of maximum voluntary isometric contraction (MVIC) in 90° of knee flexion and (2) assess how effort level in 2 different knee joint angles (60° and 90°) impacts strain in the medial and lateral regions of the patellar tendon, in 2 cohorts of patients after ACLR using a BPTB autograft (one group <24 months after surgery and another group ≥24 months after surgery).

Study design: Descriptive laboratory study.

Methods: Effort levels ranging from 20% to 100% of MVIC were performed at 90° and 60° of knee flexion on an isokinetic dynamometer, with simultaneous ultrasound imaging of tendon length to calculate regional strain. Linear mixed-effects models were used to evaluate regional strain at 60% of MVIC in 90° of knee flexion. The fixed effects of percentage of MVIC, joint angles, and time from surgery groups on patellar tendon strain were evaluated using separate models for the medial and lateral regions.

Results: Fourteen participants in the short-term group (7.5 ± 1.9 months from surgery) and 15 participants in the long-term group (71.5 ± 16.5 months from surgery) were included. At 60% of MVIC in 90° of knee flexion, the short-term group demonstrated lower patellar tendon strain than the long-term group regardless of region (P < .01). The central region also had lower strain than the medial and lateral regions regardless of group (both P < .01). Finally, the rate at which strain increased with increasing effect levels differed between time from surgery groups in both medial and lateral regions.

Conclusion: The short-term group had lower strain in all regions of the patellar tendon after ACLR using BPTB autograft. The medial and lateral regions showed varying strain based on time from surgery and effort level. Varying knee joint angles and effort levels for graft site rehabilitation may have to be considered to target specific regions of the patellar tendon.

Clinical relevance: Clinicians should consider the time elapsed since surgery and the manipulation of knee angle as factors that can exert varying levels of strain on different regions of the patellar tendon after ACLR. Accelerating quadriceps strengthening to enhance strain distribution across the patellar tendon to promote tendon healing may be of benefit for optimizing postsurgery rehabilitation.

背景:前交叉韧带重建(ACLR)通常包括采集骨-髌腱-骨(BPTB)自体移植物。移植物收获如何影响3个不同区域(内侧、外侧和中央)的肌腱劳损尚不清楚。目的:在两组使用BPTB自体移植物进行ACLR后患者中(一组研究设计:描述性实验室研究),(1)量化在膝关节屈曲90°时最大自愿等距收缩(MVIC) 60%时髌骨肌腱3个区域的应变,(2)评估2个不同膝关节角度(60°和90°)的用力水平如何影响髌骨肌腱内侧和外侧区域的应变。方法:在膝关节屈曲90°和60°时,在等速测功机上进行20%至100% MVIC的努力水平,同时超声成像肌腱长度以计算区域应变。线性混合效应模型用于评估膝关节屈曲90°时60% MVIC的区域应变。使用内侧和外侧区域的单独模型评估各组MVIC百分比、关节角度和时间对髌骨肌腱劳损的固定影响。结果:短期组14例(术后7.5±1.9个月),长期组15例(术后71.5±16.5个月)。在屈曲90°时,MVIC达到60%时,无论在哪个区域,短期组的髌骨肌腱劳损均低于长期组(P < 0.01)。各组中央区应变均低于内侧区和外侧区(P < 0.01)。最后,随着效果水平的提高,应变增加的速率在手术组的内侧和外侧区域有所不同。结论:自体BPTB移植ACLR术后,短期组髌骨肌腱各区域应变均较低。内侧和外侧区域显示不同的应变从手术的时间和努力水平。不同的膝关节角度和移植物部位康复的努力水平可能必须考虑针对特定区域的髌骨肌腱。临床相关性:临床医生应该考虑手术后的时间和膝关节角度的操纵,这是ACLR后髌骨肌腱不同区域施加不同程度张力的因素。加速股四头肌强化,增强髌骨肌腱的应变分布,促进肌腱愈合,可能有利于优化术后康复。
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引用次数: 0
Medial Meniscotibial Ligament Deficiency Increases Medial Meniscus Extrusion and Posterior Root Forces. 内侧半月板韧带缺损增加内侧半月板挤压和后根力。
IF 4.2 1区 医学 Q1 ORTHOPEDICS Pub Date : 2025-01-22 DOI: 10.1177/03635465241309671
Matthew J J Anderson, Justin F M Hollenbeck, Amelia H Drumm, Emily A Whicker, Justin R Brown, Alexander R Garcia, John M Apostolakos, Wyatt H Buchalter, Natalie Cortes, Ryan J Whalen, Armando F Vidal, Matthew T Provencher
<p><strong>Background: </strong>There is growing evidence that medial meniscotibial ligament (MTL) deficiency and medial meniscus extrusion may precede the development of some medial meniscus posterior root (MMPR) tears. However, no study has investigated the biomechanical consequences of MTL deficiency on the MMPR.</p><p><strong>Hypothesis: </strong>(1) MTL deficiency leads to increased medial meniscus extrusion, (2) increased medial meniscus extrusion is correlated with increased compression and shear forces at the MMPR, and (3) MTL repair restores medial meniscus extrusion and MMPR forces to native levels.</p><p><strong>Study design: </strong>Controlled laboratory study.</p><p><strong>Methods: </strong>Fifteen pairs of fresh-frozen cadaveric knees were tested. Specimens were organized into 3 groups according to a balanced incomplete block design: (1) native, (2) MTL deficiency, and (3) MTL repair. For the MTL deficiency group, a 3-cm deficiency in the MTL was developed under direct arthroscopic visualization. Specimens in the MTL repair group underwent a 2-anchor repair that compressed the joint capsule to the proximal tibia. All specimens were biomechanically tested in full extension with a tensile testing machine. The specimens underwent cyclic loading for 10,000 cycles at 1 Hz and compression of 20 to 500 N, with a 500-N compressive force applied for 30 seconds after the 0th, 100th, 1000th, and 10,000th cycles. Ultrasound was used to measure medial meniscus extrusion. Shear and compressive forces at the MMPR were measured with a 3-axis sensor installed inferior to the MMPR tibial attachment.</p><p><strong>Results: </strong>Medial meniscus extrusion was significantly increased in the MTL deficiency group compared with the native group (0th: 1.6 ± 0.1 mm vs 1.2 ± 0.1 mm, <i>P</i> < .05; 100th: 2.2 ± 0.2 mm vs 1.5 ± 0.2 mm, <i>P</i> < .05; 1000th: 2.8 ± 0.2 mm vs 1.8 ± 0.2 mm, <i>P</i> < .05; 10,000th: 3.5 ± 0.3 mm vs 2.1 ± 0.2 mm, <i>P</i> < .05). Compression root force was significantly increased in the MTL deficiency group compared with the native group at all cyclic loading points (0th: 21.7 ± 12.8 N vs 13.6 ± 2.4 N, <i>P</i> < .05; 100th: 18.9 ± 11.0 N vs 12.1 ± 7.5 N, <i>P</i> < .05; 1000th: 16.5 ± 9.9 N vs 11.2 ± 7.5 N, <i>P</i> < .05; 10,000th: 12.6 ± 8.6 N vs 9.0 ± 6.9 N, <i>P</i> < .05). Root shear force was significantly increased in the MTL deficiency group compared with the native group at the 0th (17.5 ± 2.5 N vs 13.6 ± 2.4 N, <i>P</i> < .001) and 100th (16.2 ± 2.6 N vs 12.1 ± 2.2 N, <i>P</i> < .001) cycles. Medial meniscus extrusion, root shear force, and compression root force of the MTL repair group were not significantly different from the native group for all cyclic loading points.</p><p><strong>Conclusion: </strong>Medial MTL deficiency led to increased medial meniscus extrusion as well as greater compression and shear forces at the MMPR compared with the intact and repaired MTL states, suggesting that MTL deficiency may pr
背景:越来越多的证据表明,内侧半月板韧带(MTL)缺陷和内侧半月板挤压可能先于一些内侧半月板后根(MMPR)撕裂的发展。然而,没有研究调查了MTL缺乏对MMPR的生物力学影响。假设:(1)MTL缺乏导致内侧半月板挤压增加,(2)内侧半月板挤压增加与MMPR处的压缩和剪切力增加有关,(3)MTL修复使内侧半月板挤压和MMPR力恢复到正常水平。研究设计:实验室对照研究。方法:对15对新鲜冷冻尸体膝关节进行检测。根据平衡的不完全块设计将标本分为3组:(1)原生,(2)MTL缺失,(3)MTL修复。对于MTL缺乏组,在直接关节镜观察下,MTL出现了3厘米的缺陷。MTL修复组的标本进行了双锚修复,将关节囊压缩到胫骨近端。所有标本均在拉力试验机上进行全伸展生物力学试验。试件在1 Hz、20 ~ 500 N的压缩条件下进行1万次循环加载,在第0次、第100次、第1000次、第10000次循环后施加500-N的压缩力30秒。超声测量内侧半月板挤压情况。MMPR的剪切力和压缩力用安装在MMPR胫骨附着体下方的3轴传感器测量。结果:与正常组相比,MTL缺乏组内侧半月板挤压明显增加(1.6±0.1 mm vs 1.2±0.1 mm, P < 0.05;第100次:2.2±0.2 mm vs 1.5±0.2 mm, P < 0.05;第1000次:2.8±0.2 mm vs 1.8±0.2 mm, P < 0.05;万分之一:3.5±0.3 mm vs 2.1±0.2 mm, P < 0.05)。MTL缺乏组在各循环加载点的根压力明显高于正常组(第0组:21.7±12.8 N vs 13.6±2.4 N, P < 0.05;第100:18.9±11.0 N vs 12.1±7.5 N, P < 0.05;第1000次:16.5±9.9 N vs 11.2±7.5 N, P < 0.05;万分之一:12.6±8.6 N vs 9.0±6.9 N, P < 0.05)。在第0(17.5±2.5 N vs 13.6±2.4 N, P < 0.001)和第100(16.2±2.6 N vs 12.1±2.2 N, P < 0.001)循环时,MTL缺乏组的根剪切力明显高于正常组。各循环加载点MTL修复组内侧半月板挤压、根剪力、根压缩力与原生组无显著差异。结论:与完整和修复的MTL状态相比,内侧MTL缺陷导致内侧半月板挤压增加,MMPR处的压缩和剪切力更大,这表明MTL缺陷可能使尸体模型的MMPR更易损伤。临床相关性:MTL缺乏使人容易内侧半月板挤压和MMPR撕裂。随后,MTL修复可以潜在地纠正内侧半月板挤压并使MMPR的力正常化。
{"title":"Medial Meniscotibial Ligament Deficiency Increases Medial Meniscus Extrusion and Posterior Root Forces.","authors":"Matthew J J Anderson, Justin F M Hollenbeck, Amelia H Drumm, Emily A Whicker, Justin R Brown, Alexander R Garcia, John M Apostolakos, Wyatt H Buchalter, Natalie Cortes, Ryan J Whalen, Armando F Vidal, Matthew T Provencher","doi":"10.1177/03635465241309671","DOIUrl":"https://doi.org/10.1177/03635465241309671","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;There is growing evidence that medial meniscotibial ligament (MTL) deficiency and medial meniscus extrusion may precede the development of some medial meniscus posterior root (MMPR) tears. However, no study has investigated the biomechanical consequences of MTL deficiency on the MMPR.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Hypothesis: &lt;/strong&gt;(1) MTL deficiency leads to increased medial meniscus extrusion, (2) increased medial meniscus extrusion is correlated with increased compression and shear forces at the MMPR, and (3) MTL repair restores medial meniscus extrusion and MMPR forces to native levels.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Study design: &lt;/strong&gt;Controlled laboratory study.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Fifteen pairs of fresh-frozen cadaveric knees were tested. Specimens were organized into 3 groups according to a balanced incomplete block design: (1) native, (2) MTL deficiency, and (3) MTL repair. For the MTL deficiency group, a 3-cm deficiency in the MTL was developed under direct arthroscopic visualization. Specimens in the MTL repair group underwent a 2-anchor repair that compressed the joint capsule to the proximal tibia. All specimens were biomechanically tested in full extension with a tensile testing machine. The specimens underwent cyclic loading for 10,000 cycles at 1 Hz and compression of 20 to 500 N, with a 500-N compressive force applied for 30 seconds after the 0th, 100th, 1000th, and 10,000th cycles. Ultrasound was used to measure medial meniscus extrusion. Shear and compressive forces at the MMPR were measured with a 3-axis sensor installed inferior to the MMPR tibial attachment.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Medial meniscus extrusion was significantly increased in the MTL deficiency group compared with the native group (0th: 1.6 ± 0.1 mm vs 1.2 ± 0.1 mm, &lt;i&gt;P&lt;/i&gt; &lt; .05; 100th: 2.2 ± 0.2 mm vs 1.5 ± 0.2 mm, &lt;i&gt;P&lt;/i&gt; &lt; .05; 1000th: 2.8 ± 0.2 mm vs 1.8 ± 0.2 mm, &lt;i&gt;P&lt;/i&gt; &lt; .05; 10,000th: 3.5 ± 0.3 mm vs 2.1 ± 0.2 mm, &lt;i&gt;P&lt;/i&gt; &lt; .05). Compression root force was significantly increased in the MTL deficiency group compared with the native group at all cyclic loading points (0th: 21.7 ± 12.8 N vs 13.6 ± 2.4 N, &lt;i&gt;P&lt;/i&gt; &lt; .05; 100th: 18.9 ± 11.0 N vs 12.1 ± 7.5 N, &lt;i&gt;P&lt;/i&gt; &lt; .05; 1000th: 16.5 ± 9.9 N vs 11.2 ± 7.5 N, &lt;i&gt;P&lt;/i&gt; &lt; .05; 10,000th: 12.6 ± 8.6 N vs 9.0 ± 6.9 N, &lt;i&gt;P&lt;/i&gt; &lt; .05). Root shear force was significantly increased in the MTL deficiency group compared with the native group at the 0th (17.5 ± 2.5 N vs 13.6 ± 2.4 N, &lt;i&gt;P&lt;/i&gt; &lt; .001) and 100th (16.2 ± 2.6 N vs 12.1 ± 2.2 N, &lt;i&gt;P&lt;/i&gt; &lt; .001) cycles. Medial meniscus extrusion, root shear force, and compression root force of the MTL repair group were not significantly different from the native group for all cyclic loading points.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Medial MTL deficiency led to increased medial meniscus extrusion as well as greater compression and shear forces at the MMPR compared with the intact and repaired MTL states, suggesting that MTL deficiency may pr","PeriodicalId":55528,"journal":{"name":"American Journal of Sports Medicine","volume":" ","pages":"3635465241309671"},"PeriodicalIF":4.2,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Lack of Joint Line Tenderness Is Consistent With a Healed Meniscus, But Positive Clinical Examination Findings and MRI Scans Are Inconsistent in Identifying Failure After Meniscal Repair: A Systematic Review and Subgroup Meta-analysis. 缺乏关节线压痛与半月板愈合一致,但阳性临床检查结果和MRI扫描在半月板修复后识别失败方面不一致:系统回顾和亚组荟萃分析。
IF 4.2 1区 医学 Q1 ORTHOPEDICS Pub Date : 2025-01-22 DOI: 10.1177/03635465241295709
Jon H Schoenecker, Luke V Tollefson, Rafat H Solaiman, Jill K Monson, Morgan D Homan, Grant J Dornan, Nicholas I Kennedy, Erik Ronnblad, Robert F LaPrade

Background: The number of meniscal repairs being completed each year is increasing; however, the optimal, cost-effective postoperative assessment to determine the success or failure of a meniscal repair is not well known.

Purpose/hypothesis: The purpose of this systematic review was to identify the clinical examination testing that correlates with objective magnetic resonance imaging (MRI) or second-look arthroscopy (SLA) findings to determine an optimal clinical workup for assessing postoperative meniscal repair healing. It was hypothesized that specific clinical tests would correlate with meniscal repairs that did not heal.

Study design: Systematic review and meta-analysis; Level of evidence, 4.

Methods: This systematic review included all clinical studies investigating meniscal repairs, meniscal repair outcomes, and meniscal healing with clinical findings, MRI, and/or SLA, published in a peer-reviewed journal and with full English text available. All included studies were evaluated for bias using the Methodological Index for Non-Randomized Studies (MINORS). The clinical tests included those using "Barrett's criteria," with the assessment of effusion, joint line tenderness, locking, McMurray testing, and radiographs. This parameter has also been abbreviated to "modified Barrett's criteria" to include only joint line tenderness, effusion, and McMurray testing.

Results: No significant correlations were found between clinical tests and MRI or SLA. A subgroup meta-analysis between Barrett's and non-Barrett's studies reported no significant subgroup differences (χ12 = 0.24; P = .62). A meta-analysis of diagnostic accuracy using a group of 7 studies that reported on true-positive, true-negative, false-positive, and false-negative data for SLA demonstrated that only a lack of joint line tenderness had a high specificity for a healed meniscal repair, with a log diagnostic odds ratio of 2.62 (95% CI, 0.47-4.76).

Conclusion: This study found no significant correlation with any specific clinical test for meniscal repair healing status using postoperative MRI and/or SLA findings. However, it was found that no healing (when compared with complete or incomplete healing) on MRI and joint line tenderness should be considered when assessing the status of postoperative meniscal repair healing. In addition, a subgroup meta-analysis found that a lack of joint line tenderness was highly correlated with a healed meniscal repair.

背景:每年完成半月板修复的数量正在增加;然而,确定半月板修复成功或失败的最佳、成本效益的术后评估尚不清楚。目的/假设:本系统综述的目的是确定与客观磁共振成像(MRI)或二次关节镜(SLA)结果相关的临床检查测试,以确定评估半月板术后修复愈合的最佳临床检查。据推测,特定的临床试验可能与半月板修复不愈合有关。研究设计:系统评价和荟萃分析;证据等级,4级。方法:本系统综述包括所有研究半月板修复、半月板修复结果和半月板愈合的临床研究,包括临床表现、MRI和/或SLA,发表在同行评审的期刊上,并有完整的英文文本。所有纳入的研究均使用非随机研究方法学指数(minor)评估偏倚。临床试验包括使用“巴雷特标准”,评估积液、关节线压痛、锁定、麦克默里试验和x线片。该参数也被简化为“修改的巴雷特标准”,仅包括关节线压痛、积液和麦克默里试验。结果:临床检查与MRI或SLA无显著相关性。Barrett研究和非Barrett研究之间的亚组荟萃分析报告没有显著的亚组差异(χ12 = 0.24;P = .62)。对一组7项研究的诊断准确性进行荟萃分析,这些研究报告了SLA的真阳性、真阴性、假阳性和假阴性数据,结果表明,只有关节线压痛缺乏对半月板修复愈合具有高特异性,对数诊断优势比为2.62 (95% CI, 0.47-4.76)。结论:本研究发现,使用术后MRI和/或SLA结果进行半月板修复愈合状态的任何特定临床测试均无显著相关性。然而,我们发现在评估半月板术后修复愈合状态时,MRI上未愈合(与完全愈合或不完全愈合相比)和关节线压痛应该被考虑。此外,一项亚组荟萃分析发现,关节线压痛的缺乏与半月板修复愈合高度相关。
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引用次数: 0
Arthroscopy Is at Least as Effective as Arthrotomy for Treatment of Septic Arthritis in Adults: A Systematic Review of Large and Intermediate Joints. 在成人脓毒性关节炎的治疗中,关节镜检查至少和关节切开术一样有效:一项关于大关节和中等关节的系统综述。
IF 4.2 1区 医学 Q1 ORTHOPEDICS Pub Date : 2025-01-11 DOI: 10.1177/03635465241285878
Brandon M Nudelman, Amit S Piple, Richard D Ferkel

Background: Surgical options for septic arthritis include open arthrotomy or an arthroscopic procedure. The optimal surgical technique remains a matter of debate as acceptable results have been reported for both.

Purpose: To evaluate the efficacy of arthroscopy versus arthrotomy for the treatment of septic arthritis in large and intermediate-sized joints.

Study design: Systematic review; Level of evidence, 3.

Methods: A literature search was performed of the PubMed and Cochrane online databases through September 2023 identifying articles comparing arthroscopy with arthrotomy for the treatment of septic arthritis. Eligible articles included retrospective or prospective comparative studies investigating reoperation, perioperative complications, or clinical outcomes after arthroscopic or open treatment for septic arthritis of the shoulder, elbow, wrist, hip, knee, or ankle in adults.

Results: In total, 23 articles with 34,248 patients met the inclusion criteria comparing arthroscopy with arthrotomy. In 14 of the 20 (70%) studies that reported on reoperation rates, there was no significant difference in arthroscopic versus open surgical management for septic arthritis. Four (20%) studies reported lower reoperation rates when arthroscopy was utilized compared with open arthrotomy. One single-institution study found arthrotomy to be more effective for shoulder septic arthritis, and another favored open surgery only in the presence of erosions. In 11 of 23 (47.8%) studies, no difference in complications or clinical outcomes was found. However, 11 of 23 (47.8%) studies comprising the shoulder, wrist, hip, knee, and ankle reported a significant benefit to arthroscopy for improved outcomes.

Conclusion: Arthroscopic surgery for the treatment of septic arthritis involving the shoulder, wrist, hip, knee, and ankle appears to be safe and effective. Reoperation rates, short-term complications, and functional outcomes tend to be similar or in favor of arthroscopy when compared with arthrotomy.

背景:脓毒性关节炎的手术选择包括开放性关节切开术或关节镜手术。最佳的手术技术仍然是一个有争议的问题,因为两种方法的结果都是可以接受的。目的:评价关节镜与关节切开术治疗大中型关节脓毒性关节炎的疗效。研究设计:系统评价;证据水平,3。方法:对PubMed和Cochrane在线数据库进行文献检索,检索截至2023年9月的比较关节镜和关节切开术治疗脓毒性关节炎的文章。符合条件的文章包括回顾性或前瞻性比较研究,调查成人肩关节、肘关节、手腕、髋关节、膝关节或踝关节化脓性关节炎的再手术、围手术期并发症或关节镜或开放治疗后的临床结果。结果:比较关节镜与关节切开术,共有23篇文章34,248例患者符合纳入标准。20项研究中有14项(70%)报道了脓毒性关节炎的再手术率,其中关节镜与开放式手术治疗没有显著差异。四项(20%)研究报告,与开放式关节切开术相比,采用关节镜手术的再手术率较低。一项单一机构的研究发现,关节切开术对肩关节脓毒性关节炎更有效,而另一项研究则倾向于只在存在糜烂的情况下进行开放手术。23项研究中有11项(47.8%)未发现并发症或临床结果的差异。然而,23项研究中有11项(47.8%)包括肩关节、腕关节、髋关节、膝关节和踝关节,报告了关节镜对改善预后的显著益处。结论:关节镜手术治疗累及肩、腕、髋、膝和踝关节的脓毒性关节炎安全有效。与关节切开术相比,关节镜手术的再手术率、短期并发症和功能结果趋向相似或更有利于关节镜手术。
{"title":"Arthroscopy Is at Least as Effective as Arthrotomy for Treatment of Septic Arthritis in Adults: A Systematic Review of Large and Intermediate Joints.","authors":"Brandon M Nudelman, Amit S Piple, Richard D Ferkel","doi":"10.1177/03635465241285878","DOIUrl":"https://doi.org/10.1177/03635465241285878","url":null,"abstract":"<p><strong>Background: </strong>Surgical options for septic arthritis include open arthrotomy or an arthroscopic procedure. The optimal surgical technique remains a matter of debate as acceptable results have been reported for both.</p><p><strong>Purpose: </strong>To evaluate the efficacy of arthroscopy versus arthrotomy for the treatment of septic arthritis in large and intermediate-sized joints.</p><p><strong>Study design: </strong>Systematic review; Level of evidence, 3.</p><p><strong>Methods: </strong>A literature search was performed of the PubMed and Cochrane online databases through September 2023 identifying articles comparing arthroscopy with arthrotomy for the treatment of septic arthritis. Eligible articles included retrospective or prospective comparative studies investigating reoperation, perioperative complications, or clinical outcomes after arthroscopic or open treatment for septic arthritis of the shoulder, elbow, wrist, hip, knee, or ankle in adults.</p><p><strong>Results: </strong>In total, 23 articles with 34,248 patients met the inclusion criteria comparing arthroscopy with arthrotomy. In 14 of the 20 (70%) studies that reported on reoperation rates, there was no significant difference in arthroscopic versus open surgical management for septic arthritis. Four (20%) studies reported lower reoperation rates when arthroscopy was utilized compared with open arthrotomy. One single-institution study found arthrotomy to be more effective for shoulder septic arthritis, and another favored open surgery only in the presence of erosions. In 11 of 23 (47.8%) studies, no difference in complications or clinical outcomes was found. However, 11 of 23 (47.8%) studies comprising the shoulder, wrist, hip, knee, and ankle reported a significant benefit to arthroscopy for improved outcomes.</p><p><strong>Conclusion: </strong>Arthroscopic surgery for the treatment of septic arthritis involving the shoulder, wrist, hip, knee, and ankle appears to be safe and effective. Reoperation rates, short-term complications, and functional outcomes tend to be similar or in favor of arthroscopy when compared with arthrotomy.</p>","PeriodicalId":55528,"journal":{"name":"American Journal of Sports Medicine","volume":" ","pages":"3635465241285878"},"PeriodicalIF":4.2,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High Rate of Return to Sport for Athletes Undergoing Articular Cartilage Restoration Procedures for the Knee: A Systematic Review of Contemporary Studies. 接受膝关节关节软骨修复手术的运动员重返运动的高比率:当代研究的系统回顾。
IF 4.2 1区 医学 Q1 ORTHOPEDICS Pub Date : 2025-01-10 DOI: 10.1177/03635465241280975
Kyle N Kunze, Michael Mazzucco, Zach Thomas, Robert Uzzo, Scott A Rodeo, Russell F Warren, Thomas L Wickiewicz, Riley J Williams

Background: Continued advancements in cartilage surgery and an accumulating body of evidence warrants a contemporary synthesis of return to sport (RTS) outcomes to provide updated prognostic data and to better understand treatment response.

Purpose: To perform an updated systematic review of RTS in athletes after knee cartilage restoration surgery.

Study design: Systematic review; Level of evidence, 4.

Methods: PubMed, OVID/Medline, and Cochrane databases were queried in October 2023 for studies reporting any RTS outcome after knee cartilage restoration surgery. Meta-analyses with inverse-variance proportion and DerSimonian-Laird random-effects estimators were applied to quantify overall RTS. Comparative proportional subgroup meta-analyses with relative odds ratios (ORs) were constructed to quantify (1) the influence of the procedure on RTS and (2) RTS ability (lower vs same/greater level of play) based on procedure, competition level, and specific sport.

Results: A total of 52 studies (n = 2387) were included. The overall pooled RTS was 80.3% (95% CI, 73.3%-86.5%). Matrix-assisted chondrocyte implantation (MACI) (OR, 2.15) and osteochondral autograft transplantation system (OATS) (OR, 1.83) demonstrated the highest likelihoods of RTS at the same/greater level, while microfracture (MF) (OR, 0.78) was the only treatment demonstrating a higher likelihood of RTS at a lower level. The fastest mean RTS was observed after OATS (6.6 ± 2.6 months). Professional athletes demonstrated an OR of 1.01 for RTS at the same/greater level, whereas recreational/amateur athletes demonstrated an OR of 1.63; however, all professional athletes underwent MF, and recreational/amateur athletes who underwent MF demonstrated lower likelihoods of RTS (OR, 0.78), indicating a consistent association between MF and low RTS propensity. Basketball players demonstrated the lowest likelihood of RTS at the same/greater level (OR, 1.1), while American football and soccer were associated with high likelihoods of RTS (OR, 3 and 2.4, respectively) across all procedure types.

Conclusion: Cartilage restoration allows for high overall RTS, with OATS and MACI conferring the greatest propensity for RTS, while OATS allowed for the fastest RTS. Undergoing MF was associated with consistently poor RTS ability. This study identified several important associations between the level of RTS and clinically relevant factors when discussing RTS, with recreational/amateur athletes, soccer players, and American football players demonstrating a higher relative propensity to RTS.

背景:软骨手术的持续进步和越来越多的证据证明了对RTS(重返运动)结果的当代综合研究,以提供最新的预后数据并更好地了解治疗反应。目的:对运动员膝关节软骨修复手术后的RTS进行最新的系统回顾。研究设计:系统评价;证据等级,4级。方法:于2023年10月查询PubMed、OVID/Medline和Cochrane数据库,以获取报告膝关节软骨修复手术后RTS结果的研究。meta分析采用反方差比例和dersimonan - laird随机效应估计量来量化总体RTS。构建了相对优势比(ORs)的比较比例亚组荟萃分析,以量化(1)程序对RTS的影响;(2)基于程序、竞争水平和特定运动的RTS能力(较低与相同/更高水平的游戏)。结果:共纳入52项研究(n = 2387)。总合并RTS为80.3% (95% CI, 73.3%-86.5%)。基质辅助软骨细胞植入(MACI) (OR, 2.15)和骨软骨自体移植系统(OATS) (OR, 1.83)在相同或更高水平上显示RTS的可能性最高,而微骨折(MF) (OR, 0.78)是唯一显示RTS在较低水平上可能性较高的治疗方法。ats后平均RTS最快(6.6±2.6个月)。职业运动员在相同或更高水平的RTS上的OR为1.01,而休闲/业余运动员的OR为1.63;然而,所有的职业运动员都经历了MF,而娱乐/业余运动员经历了MF,他们表现出较低的RTS可能性(OR, 0.78),这表明MF和低RTS倾向之间存在一致的关联。篮球运动员在相同或更高水平上表现出最低的RTS可能性(OR, 1.1),而美式足球和足球运动员在所有程序类型中表现出较高的RTS可能性(OR分别为3和2.4)。结论:软骨修复允许高整体RTS,其中燕麦和MACI赋予最大的RTS倾向,而燕麦允许最快的RTS。接受MF与持续较差的RTS能力相关。在讨论RTS时,该研究确定了RTS水平与临床相关因素之间的几个重要关联,休闲/业余运动员、足球运动员和美式足球运动员表现出更高的RTS相对倾向。
{"title":"High Rate of Return to Sport for Athletes Undergoing Articular Cartilage Restoration Procedures for the Knee: A Systematic Review of Contemporary Studies.","authors":"Kyle N Kunze, Michael Mazzucco, Zach Thomas, Robert Uzzo, Scott A Rodeo, Russell F Warren, Thomas L Wickiewicz, Riley J Williams","doi":"10.1177/03635465241280975","DOIUrl":"https://doi.org/10.1177/03635465241280975","url":null,"abstract":"<p><strong>Background: </strong>Continued advancements in cartilage surgery and an accumulating body of evidence warrants a contemporary synthesis of return to sport (RTS) outcomes to provide updated prognostic data and to better understand treatment response.</p><p><strong>Purpose: </strong>To perform an updated systematic review of RTS in athletes after knee cartilage restoration surgery.</p><p><strong>Study design: </strong>Systematic review; Level of evidence, 4.</p><p><strong>Methods: </strong>PubMed, OVID/Medline, and Cochrane databases were queried in October 2023 for studies reporting any RTS outcome after knee cartilage restoration surgery. Meta-analyses with inverse-variance proportion and DerSimonian-Laird random-effects estimators were applied to quantify overall RTS. Comparative proportional subgroup meta-analyses with relative odds ratios (ORs) were constructed to quantify (1) the influence of the procedure on RTS and (2) RTS ability (lower vs same/greater level of play) based on procedure, competition level, and specific sport.</p><p><strong>Results: </strong>A total of 52 studies (n = 2387) were included. The overall pooled RTS was 80.3% (95% CI, 73.3%-86.5%). Matrix-assisted chondrocyte implantation (MACI) (OR, 2.15) and osteochondral autograft transplantation system (OATS) (OR, 1.83) demonstrated the highest likelihoods of RTS at the same/greater level, while microfracture (MF) (OR, 0.78) was the only treatment demonstrating a higher likelihood of RTS at a lower level. The fastest mean RTS was observed after OATS (6.6 ± 2.6 months). Professional athletes demonstrated an OR of 1.01 for RTS at the same/greater level, whereas recreational/amateur athletes demonstrated an OR of 1.63; however, all professional athletes underwent MF, and recreational/amateur athletes who underwent MF demonstrated lower likelihoods of RTS (OR, 0.78), indicating a consistent association between MF and low RTS propensity. Basketball players demonstrated the lowest likelihood of RTS at the same/greater level (OR, 1.1), while American football and soccer were associated with high likelihoods of RTS (OR, 3 and 2.4, respectively) across all procedure types.</p><p><strong>Conclusion: </strong>Cartilage restoration allows for high overall RTS, with OATS and MACI conferring the greatest propensity for RTS, while OATS allowed for the fastest RTS. Undergoing MF was associated with consistently poor RTS ability. This study identified several important associations between the level of RTS and clinically relevant factors when discussing RTS, with recreational/amateur athletes, soccer players, and American football players demonstrating a higher relative propensity to RTS.</p>","PeriodicalId":55528,"journal":{"name":"American Journal of Sports Medicine","volume":" ","pages":"3635465241280975"},"PeriodicalIF":4.2,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Return to Work, Sport, and Sport- Related Activity After Distal Triceps Tendon Repair: A Systematic Review. 三头远端肌腱修复后重返工作、运动和运动相关活动:系统回顾。
IF 4.2 1区 医学 Q1 ORTHOPEDICS Pub Date : 2025-01-10 DOI: 10.1177/03635465241283970
William L Johns, Benjamin H Miltenberg, Anthony N Baumann, Nazanin Kermanshahi, Rahul R Muchintala, Steven B Cohen

Background: Distal triceps tendon injuries are relatively rare injuries, often occurring in highly active patients with physically demanding jobs or lifestyles. Information on return to work, sport, and activity is essential for patient education and counseling after a distal triceps tendon rupture.

Purpose: To determine the rates of return to work, sport, and sport-related activity after distal triceps tendon repair.

Study design: Systematic review; Level of evidence, 4.

Methods: PubMed, CINAHL, MEDLINE, Web of Science, and SPORTDiscus were queried from the earliest record through January 12, 2024. Articles were included if they examined return to various activities (exercise, sport, work, or military duty) after distal triceps tendon repair. Data on return to sport/work/activity were collected as well as information on patient satisfaction, pre-existing medical history or medication use (ie, anabolic steroids or corticosteroids), and complications. Article quality was assessed via the Methodological Index for Non-Randomized Studies (MINORS) scale.

Results: Of 164 articles initially retrieved, 10 retrospective studies were included. Patients (n = 318; 74.2% male, 25.8% female) who underwent distal triceps tendon repair had a mean age of 44.7 ± 5.5 years with a mean follow-up time of 52.6 ± 21.4 months. After distal triceps tendon repair, 93.3% of patients (112/120) returned to sport, 95.3% (81/85) returned to military duty, and 92.6% (100/108) returned to work. Of the studies that evaluated satisfaction, the majority of patients reported high satisfaction after surgery. The overall complication rate (ranging from persistent pain and wound complications to nerve injuries and reruptures) after distal triceps tendon repair was 18.0%, the rerupture rate (complete and partial) was 7.2%, and the reoperation rate was 3.9%, with all partial reruptures undergoing nonoperative care.

Conclusion: A distal triceps tendon rupture is a rare but potentially challenging injury, traditionally occurring in an active population, and often requires surgical repair. Importantly, >90% of an active-duty military population, athletes, and the general workforce was able to return to sport or their respective activity after surgery. Furthermore, there was high patient satisfaction and low rates of complications and reoperations after distal triceps tendon repair.

背景:远端肱三头肌肌腱损伤是相对罕见的损伤,通常发生在体力要求高的工作或生活方式的高活动患者中。在远端肱三头肌肌腱断裂后,恢复工作、运动和活动的信息对于患者教育和咨询是必不可少的。目的:确定远端肱三头肌肌腱修复后恢复工作、运动和运动相关活动的比率。研究设计:系统评价;证据等级,4级。方法:查询PubMed、CINAHL、MEDLINE、Web of Science、SPORTDiscus等最早记录至2024年1月12日的文献。如果文章检查了远端肱三头肌肌腱修复后的各种活动(锻炼、运动、工作或军事任务)的恢复情况,则纳入研究。收集了恢复运动/工作/活动的数据,以及患者满意度、既往病史或药物使用(即合成代谢类固醇或皮质类固醇)和并发症的信息。文章质量通过非随机研究方法学指数(minor)量表进行评估。结果:在最初检索的164篇文章中,纳入了10篇回顾性研究。患者(n = 318;74.2%男性,25.8%女性)行肱三头肌远端肌腱修复术,平均年龄44.7±5.5岁,平均随访时间52.6±21.4个月。肱三头肌远端肌腱修复后,93.3%(112/120)的患者恢复运动,95.3%(81/85)的患者恢复服兵役,92.6%(100/108)的患者恢复工作。在评估满意度的研究中,大多数患者报告术后满意度很高。三头远端肌腱修复后的总并发症发生率(从持续疼痛和伤口并发症到神经损伤和再破)为18.0%,再破率(完全和部分)为7.2%,再手术率为3.9%,所有部分再破均接受非手术治疗。结论:肱三头肌腱远端断裂是一种罕见但具有潜在挑战性的损伤,传统上发生在运动人群中,通常需要手术修复。重要的是,90%的现役军人、运动员和一般劳动力在手术后能够恢复运动或各自的活动。此外,患者满意度高,术后并发症和再手术率低。
{"title":"Return to Work, Sport, and Sport- Related Activity After Distal Triceps Tendon Repair: A Systematic Review.","authors":"William L Johns, Benjamin H Miltenberg, Anthony N Baumann, Nazanin Kermanshahi, Rahul R Muchintala, Steven B Cohen","doi":"10.1177/03635465241283970","DOIUrl":"https://doi.org/10.1177/03635465241283970","url":null,"abstract":"<p><strong>Background: </strong>Distal triceps tendon injuries are relatively rare injuries, often occurring in highly active patients with physically demanding jobs or lifestyles. Information on return to work, sport, and activity is essential for patient education and counseling after a distal triceps tendon rupture.</p><p><strong>Purpose: </strong>To determine the rates of return to work, sport, and sport-related activity after distal triceps tendon repair.</p><p><strong>Study design: </strong>Systematic review; Level of evidence, 4.</p><p><strong>Methods: </strong>PubMed, CINAHL, MEDLINE, Web of Science, and SPORTDiscus were queried from the earliest record through January 12, 2024. Articles were included if they examined return to various activities (exercise, sport, work, or military duty) after distal triceps tendon repair. Data on return to sport/work/activity were collected as well as information on patient satisfaction, pre-existing medical history or medication use (ie, anabolic steroids or corticosteroids), and complications. Article quality was assessed via the Methodological Index for Non-Randomized Studies (MINORS) scale.</p><p><strong>Results: </strong>Of 164 articles initially retrieved, 10 retrospective studies were included. Patients (n = 318; 74.2% male, 25.8% female) who underwent distal triceps tendon repair had a mean age of 44.7 ± 5.5 years with a mean follow-up time of 52.6 ± 21.4 months. After distal triceps tendon repair, 93.3% of patients (112/120) returned to sport, 95.3% (81/85) returned to military duty, and 92.6% (100/108) returned to work. Of the studies that evaluated satisfaction, the majority of patients reported high satisfaction after surgery. The overall complication rate (ranging from persistent pain and wound complications to nerve injuries and reruptures) after distal triceps tendon repair was 18.0%, the rerupture rate (complete and partial) was 7.2%, and the reoperation rate was 3.9%, with all partial reruptures undergoing nonoperative care.</p><p><strong>Conclusion: </strong>A distal triceps tendon rupture is a rare but potentially challenging injury, traditionally occurring in an active population, and often requires surgical repair. Importantly, >90% of an active-duty military population, athletes, and the general workforce was able to return to sport or their respective activity after surgery. Furthermore, there was high patient satisfaction and low rates of complications and reoperations after distal triceps tendon repair.</p>","PeriodicalId":55528,"journal":{"name":"American Journal of Sports Medicine","volume":" ","pages":"3635465241283970"},"PeriodicalIF":4.2,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PRP Injections for the Treatment of Knee Osteoarthritis: The Improvement Is Clinically Significant and Influenced by Platelet Concentration: A Meta-analysis of Randomized Controlled Trials. 注射 PRP 治疗膝骨关节炎:改善具有临床意义且受血小板浓度影响:随机对照试验的元分析》。
IF 4.2 1区 医学 Q1 ORTHOPEDICS Pub Date : 2025-01-03 DOI: 10.1177/03635465241246524
Alessandro Bensa, Davide Previtali, Alessandro Sangiorgio, Angelo Boffa, Manuela Salerno, Giuseppe Filardo
<p><strong>Background: </strong>Platelet-rich plasma (PRP) has emerged as a promising therapeutic intervention for knee osteoarthritis (OA), attracting substantial clinical and research attention. However, the clinical relevance of the treatment benefit remains controversial.</p><p><strong>Purpose: </strong>To evaluate the effectiveness of PRP compared with placebo in patients with knee OA in terms of minimal clinically important difference (MCID) and to investigate the possible influence of platelet concentration on the clinical outcome.</p><p><strong>Study design: </strong>Meta-analysis. Level of evidence 1.</p><p><strong>Methods: </strong>The search was conducted on 5 databases (PubMed, Cochrane Library, Scopus, Embase, Web of Science) using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Inclusion criteria were randomized controlled trials comparing PRP and placebo injections to treat knee OA, written in the English language, with no time limitation. The effects were quantified at 1-, 3-, 6-, and 12-month follow-up points. Visual analog scale (VAS) for pain and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores were used, with subanalyses based on platelet concentration performed using a 1,000,000 ± 20% platelets/µL cutoff. The MCID values (VAS, 1.37; WOMAC, 6.4) were used to interpret clinical improvement. The articles' quality was assessed using the Revised Tool for Risk of Bias in Randomized Trials and the Grading of Recommendations Assessment, Development and Evaluation guidelines.</p><p><strong>Results: </strong>Among the 5499 articles retrieved, 18 randomized controlled trials (1995 patients) were included. PRP presented statistically superior improvements in VAS and WOMAC scores compared with placebo at all follow-up points, exceeding the MCID at 3- and 6-month follow-up points for VAS and at all follow-up points for WOMAC. The subanalysis based on platelet concentration showed that high-platelet PRP provided clinically significant pain relief with the improvement exceeding the MCID compared with placebo at 3-, 6-, and 12-month follow-up points. In contrast, low-platelet PRP failed to offer a clinically perceivable benefit in terms of VAS score. WOMAC results showed that both products provided a clinically significant improvement at 3 and 6 months of follow-up. This benefit was maintained up to the 12-month follow-up in the high-platelet group but not in the low-platelet group, where the improvement compared with placebo did not reach statistical significance.</p><p><strong>Conclusion: </strong>This meta-analysis showed that PRP offered clinically relevant functional improvement at 1-, 3-, 6-, and 12-month follow-up points and pain relief at 3- and 6-month follow-up points compared with placebo for the treatment of knee OA. Platelet concentration was found to influence treatment efficacy, with high-platelet PRP providing superior pain relief and more durable functio
背景:富血小板血浆(PRP)已成为一种有前景的膝关节骨关节炎(OA)治疗干预措施,吸引了大量的临床和研究关注。然而,治疗益处的临床相关性仍然存在争议。目的:评价PRP与安慰剂在膝关节OA患者的最小临床重要差异(MCID)方面的有效性,并探讨血小板浓度对临床结局的可能影响。研究设计:荟萃分析。证据水平1。方法:在5个数据库(PubMed, Cochrane Library, Scopus, Embase, Web of Science)中使用PRISMA(首选系统评价和meta分析报告项目)指南进行检索。纳入标准是比较PRP和安慰剂注射治疗膝关节OA的随机对照试验,以英文书写,没有时间限制。在1个月、3个月、6个月和12个月的随访点对效果进行量化。使用视觉模拟疼痛量表(VAS)和西安大略大学和麦克马斯特大学骨关节炎指数(WOMAC)评分,并以血小板浓度为基础进行亚分析,血小板浓度为1,000,000±20% /µL。MCID值(VAS, 1.37;WOMAC评分6.4)来解释临床改善。采用随机试验偏倚风险修正工具和推荐分级评估、发展和评价指南对文章质量进行评估。结果:在5499篇文献中,纳入18项随机对照试验(1995例)。与安慰剂相比,PRP在VAS和WOMAC评分方面的改善在所有随访点上都具有统计学上的优势,在VAS随访3个月和6个月以及WOMAC随访的所有随访点上都超过了MCID。基于血小板浓度的亚分析显示,在3个月、6个月和12个月的随访点,与安慰剂相比,高血小板PRP提供了具有临床意义的疼痛缓解,其改善程度超过了MCID。相比之下,低血小板PRP在VAS评分方面未能提供临床可感知的益处。WOMAC结果显示,两种产品在随访3个月和6个月时均有显著的临床改善。在高血小板组中,这种益处一直维持到12个月的随访,而在低血小板组中则没有,与安慰剂相比,这种改善没有达到统计学意义。结论:该荟萃分析显示,与安慰剂相比,PRP在治疗膝关节OA的1、3、6和12个月随访时提供了临床相关的功能改善,在3和6个月随访时提供了疼痛缓解。发现血小板浓度影响治疗效果,与低血小板PRP相比,高血小板PRP提供更好的疼痛缓解和更持久的功能改善。
{"title":"PRP Injections for the Treatment of Knee Osteoarthritis: The Improvement Is Clinically Significant and Influenced by Platelet Concentration: A Meta-analysis of Randomized Controlled Trials.","authors":"Alessandro Bensa, Davide Previtali, Alessandro Sangiorgio, Angelo Boffa, Manuela Salerno, Giuseppe Filardo","doi":"10.1177/03635465241246524","DOIUrl":"https://doi.org/10.1177/03635465241246524","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Platelet-rich plasma (PRP) has emerged as a promising therapeutic intervention for knee osteoarthritis (OA), attracting substantial clinical and research attention. However, the clinical relevance of the treatment benefit remains controversial.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;To evaluate the effectiveness of PRP compared with placebo in patients with knee OA in terms of minimal clinically important difference (MCID) and to investigate the possible influence of platelet concentration on the clinical outcome.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Study design: &lt;/strong&gt;Meta-analysis. Level of evidence 1.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The search was conducted on 5 databases (PubMed, Cochrane Library, Scopus, Embase, Web of Science) using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Inclusion criteria were randomized controlled trials comparing PRP and placebo injections to treat knee OA, written in the English language, with no time limitation. The effects were quantified at 1-, 3-, 6-, and 12-month follow-up points. Visual analog scale (VAS) for pain and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores were used, with subanalyses based on platelet concentration performed using a 1,000,000 ± 20% platelets/µL cutoff. The MCID values (VAS, 1.37; WOMAC, 6.4) were used to interpret clinical improvement. The articles' quality was assessed using the Revised Tool for Risk of Bias in Randomized Trials and the Grading of Recommendations Assessment, Development and Evaluation guidelines.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Among the 5499 articles retrieved, 18 randomized controlled trials (1995 patients) were included. PRP presented statistically superior improvements in VAS and WOMAC scores compared with placebo at all follow-up points, exceeding the MCID at 3- and 6-month follow-up points for VAS and at all follow-up points for WOMAC. The subanalysis based on platelet concentration showed that high-platelet PRP provided clinically significant pain relief with the improvement exceeding the MCID compared with placebo at 3-, 6-, and 12-month follow-up points. In contrast, low-platelet PRP failed to offer a clinically perceivable benefit in terms of VAS score. WOMAC results showed that both products provided a clinically significant improvement at 3 and 6 months of follow-up. This benefit was maintained up to the 12-month follow-up in the high-platelet group but not in the low-platelet group, where the improvement compared with placebo did not reach statistical significance.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;This meta-analysis showed that PRP offered clinically relevant functional improvement at 1-, 3-, 6-, and 12-month follow-up points and pain relief at 3- and 6-month follow-up points compared with placebo for the treatment of knee OA. Platelet concentration was found to influence treatment efficacy, with high-platelet PRP providing superior pain relief and more durable functio","PeriodicalId":55528,"journal":{"name":"American Journal of Sports Medicine","volume":" ","pages":"3635465241246524"},"PeriodicalIF":4.2,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Return to Play After Arthroscopic Superior Labral Repair: A Systematic Review. 关节镜下上唇修复后重返赛场:系统回顾。
IF 4.2 1区 医学 Q1 ORTHOPEDICS Pub Date : 2025-01-03 DOI: 10.1177/03635465241246122
Dana G Rowe, Eoghan T Hurley, Mikhail A Bethell, Samuel G Lorentz, Alex M Meyer, Christopher S Klifto, Brian C Lau, Dean C Taylor, Jonathan F Dickens

Background: Superior labral tears are common shoulder injuries among athletes, and for athletes undergoing surgical intervention, one of the main priorities is to return to preinjury levels of activity in a timely manner. However, the literature surrounding return to play after superior labral repair presents inconsistent results, with limited studies evaluating the timing of return to play.

Purpose: To systematically review the rate and timing of return to play in athletes after arthroscopic superior labral repair.

Study design: Systematic review; Level of evidence, 4.

Methods: A systematic literature search was conducted based on PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, using the PubMed, EMBASE, and Cochrane Library databases. Eligible for inclusion were clinical studies reporting on return to play after arthroscopic superior labral repair. Subgroup analysis was conducted for overhead and collision athletes as well as for return to duty among military personnel. Meta-analysis was performed using Review Manager to compare superior labral repair to biceps tenodesis in the subset of studies comparing these treatments directly. A P value <.05 was considered to be statistically significant.

Results: This review identified 42 studies including 1759 unique cases meeting the inclusion criteria. The majority of patients were male (76.7%), with a mean age of 31.5 years (range, 15-75 years) and a mean follow-up of 50.4 months. The overall rate of return to sport was 77.5%, with 68.2% returning to the same level at a mean of 8.2 months. In overhead athletes, the overall rate of return to play was 69.9% and the rate of return to preinjury level was 55.5%. In collision and contact athletes, the overall rate of return to play was 77.2% and the rate of return to preinjury level was 70.2%. Among military personnel, the overall rate of return to duty was 83.4%, and 81.7% returned to preinjury level at a mean of 4.4 months. In the studies comparing return to play after superior labral repair and biceps tenodesis, a nonsignificant difference was found (risk ratio, 0.92; 95% CI, 0.85-1.00; I2 = 13%; P = .05).

Conclusion: Overall, nearly a quarter of athletes were unable to return to play after arthroscopic superior labral repair. However, a high rate of return to duty was found among the military population treated with arthroscopic superior labral repair.

背景:上唇撕裂是运动员中常见的肩部损伤,对于接受手术干预的运动员来说,首要任务之一是及时恢复到损伤前的活动水平。然而,关于上唇修复后恢复比赛的文献给出了不一致的结果,有限的研究评估了恢复比赛的时间。目的:系统回顾关节镜下上唇修复术后运动员的恢复率和恢复时间。研究设计:系统评价;证据等级,4级。方法:采用PubMed、EMBASE和Cochrane图书馆数据库,根据PRISMA(系统评价和荟萃分析首选报告项目)指南进行系统文献检索。符合纳入条件的是报告关节镜下上唇修复术后恢复的临床研究。对头顶和碰撞运动员进行亚组分析,并对军人复职进行亚组分析。使用Review Manager进行meta分析,比较上唇修复与二头肌肌腱固定术在直接比较这些治疗的研究子集中的差异。结果:本综述确定了42项研究,包括1759例符合纳入标准的独特病例。患者以男性居多(76.7%),平均年龄31.5岁(15 ~ 75岁),平均随访50.4个月。总体恢复运动的比率为77.5%,其中68.2%在平均8.2个月后恢复到相同水平。头顶运动员的总体恢复率为69.9%,恢复到伤前水平的比率为55.5%。碰撞和接触运动员的总体恢复率为77.2%,恢复到伤前水平的率为70.2%。军人总体复职率为83.4%,平均4.4个月恢复到伤前水平的为81.7%。在比较上唇修复和二头肌肌腱固定术后恢复比赛的研究中,发现无显著差异(风险比,0.92;95% ci, 0.85-1.00;I2 = 13%;P = 0.05)。结论:总体而言,近四分之一的运动员在关节镜下上唇修复后无法重返赛场。然而,在接受关节镜下上唇修复术的军人中,复职率很高。
{"title":"Return to Play After Arthroscopic Superior Labral Repair: A Systematic Review.","authors":"Dana G Rowe, Eoghan T Hurley, Mikhail A Bethell, Samuel G Lorentz, Alex M Meyer, Christopher S Klifto, Brian C Lau, Dean C Taylor, Jonathan F Dickens","doi":"10.1177/03635465241246122","DOIUrl":"https://doi.org/10.1177/03635465241246122","url":null,"abstract":"<p><strong>Background: </strong>Superior labral tears are common shoulder injuries among athletes, and for athletes undergoing surgical intervention, one of the main priorities is to return to preinjury levels of activity in a timely manner. However, the literature surrounding return to play after superior labral repair presents inconsistent results, with limited studies evaluating the timing of return to play.</p><p><strong>Purpose: </strong>To systematically review the rate and timing of return to play in athletes after arthroscopic superior labral repair.</p><p><strong>Study design: </strong>Systematic review; Level of evidence, 4.</p><p><strong>Methods: </strong>A systematic literature search was conducted based on PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, using the PubMed, EMBASE, and Cochrane Library databases. Eligible for inclusion were clinical studies reporting on return to play after arthroscopic superior labral repair. Subgroup analysis was conducted for overhead and collision athletes as well as for return to duty among military personnel. Meta-analysis was performed using Review Manager to compare superior labral repair to biceps tenodesis in the subset of studies comparing these treatments directly. A <i>P</i> value <.05 was considered to be statistically significant.</p><p><strong>Results: </strong>This review identified 42 studies including 1759 unique cases meeting the inclusion criteria. The majority of patients were male (76.7%), with a mean age of 31.5 years (range, 15-75 years) and a mean follow-up of 50.4 months. The overall rate of return to sport was 77.5%, with 68.2% returning to the same level at a mean of 8.2 months. In overhead athletes, the overall rate of return to play was 69.9% and the rate of return to preinjury level was 55.5%. In collision and contact athletes, the overall rate of return to play was 77.2% and the rate of return to preinjury level was 70.2%. Among military personnel, the overall rate of return to duty was 83.4%, and 81.7% returned to preinjury level at a mean of 4.4 months. In the studies comparing return to play after superior labral repair and biceps tenodesis, a nonsignificant difference was found (risk ratio, 0.92; 95% CI, 0.85-1.00; <i>I</i><sup>2</sup> = 13%; <i>P</i> = .05).</p><p><strong>Conclusion: </strong>Overall, nearly a quarter of athletes were unable to return to play after arthroscopic superior labral repair. However, a high rate of return to duty was found among the military population treated with arthroscopic superior labral repair.</p>","PeriodicalId":55528,"journal":{"name":"American Journal of Sports Medicine","volume":" ","pages":"3635465241246122"},"PeriodicalIF":4.2,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microfragmented Adipose Tissue Has No Advantage Over Platelet-Rich Plasma and Bone Marrow Aspirate Injections for Symptomatic Knee Osteoarthritis: A Systematic Review and Meta-analysis. 对于症状性膝骨关节炎,微碎片化脂肪组织比富血小板血浆和骨髓抽吸注射没有优势:一项系统回顾和荟萃分析。
IF 4.2 1区 医学 Q1 ORTHOPEDICS Pub Date : 2025-01-03 DOI: 10.1177/03635465241249940
Erik Hohmann, Natalie Keough, Rachel M Frank, Scott A Rodeo

Background: Microfragmented adipose tissue has been proposed for intra-articular treatment of knee osteoarthritis. There are little data comparing the outcomes of treatment between microfragmented adipose tissue and other biological treatments.

Purpose: To perform a systematic review and meta-analysis comparing microfragmented aspirated fat injections to other orthobiologics, hyaluronic acid, and corticosteroid injections for symptomatic knee osteoarthritis.

Study design: Systematic review and meta-analysis; Level of evidence, 2.

Methods: A systematic review of the literature was performed to identify pertinent publications in the MEDLINE, Embase, Scopus, and Google Scholar databases, including all level 1 to 3 studies from 2000 to 2023. Validated knee scores (visual analog scale [VAS] for pain, Knee injury and Osteoarthritis Outcome Score [KOOS], Lysholm, International Knee Documentation Committee) were included as outcome measures. Risk of bias was assessed using Cochrane tools. The Grading of Recommendations Assessment, Development and Evaluation system was used to assess the quality of the body of evidence and the modified Coleman Methodology Score was used to assess study quality. Heterogeneity was assessed using χ2 and I2 statistics.

Results: Five studies were included in the analysis. One study had a high risk of bias; 4 studies had some risk of bias. The overall study quality was fair, and the certainty of evidence was low. The pooled estimate for VAS scores did not demonstrate significant differences at 3, 6, and 12 months. The pooled estimate for the KOOS Pain, Symptoms, Activities of Daily Living, Sport and Recreation, and Quality of Life subscales did not demonstrate significant differences at 3, 6, and 12 months.

Conclusion: The results of this systematic review and meta-analysis demonstrated that there were no statistically significant differences for both the clinical outcomes and pain scores between microfragmented adipose tissue and other orthobiologics for the treatment of knee osteoarthritis. However, modest study quality, some risk of bias, and low certainty of evidence reduce external validity, and these results must be viewed with some caution.

背景:微碎片化脂肪组织已被提议用于膝关节骨性关节炎的关节内治疗。很少有数据比较微碎片化脂肪组织和其他生物治疗之间的治疗结果。目的:进行系统回顾和荟萃分析,比较微碎片抽吸脂肪注射与其他骨科、透明质酸和皮质类固醇注射治疗症状性膝骨关节炎。研究设计:系统评价和荟萃分析;证据等级2。方法:对MEDLINE、Embase、Scopus和谷歌Scholar数据库中的相关文献进行系统综述,包括2000年至2023年的所有1至3级研究。经验证的膝关节评分(疼痛视觉模拟量表[VAS],膝关节损伤和骨关节炎结局评分[oos], Lysholm,国际膝关节文献委员会)被纳入结果测量。使用Cochrane工具评估偏倚风险。建议评估、发展和评价分级系统用于评估证据体的质量,改进的Coleman方法学评分用于评估研究质量。采用χ2和I2统计分析异质性。结果:5项研究被纳入分析。一项研究有很高的偏倚风险;4项研究存在一定的偏倚风险。总体研究质量尚可,证据的确定性较低。VAS评分的汇总估计在3、6和12个月时没有显着差异。kos疼痛、症状、日常生活活动、运动和娱乐以及生活质量亚量表的汇总估计在3、6和12个月时没有显示出显著差异。结论:本系统综述和荟萃分析的结果表明,微碎片化脂肪组织与其他骨科治疗膝关节骨关节炎的临床结果和疼痛评分无统计学差异。然而,适度的研究质量、一定的偏倚风险和证据的低确定性降低了外部效度,必须谨慎看待这些结果。
{"title":"Microfragmented Adipose Tissue Has No Advantage Over Platelet-Rich Plasma and Bone Marrow Aspirate Injections for Symptomatic Knee Osteoarthritis: A Systematic Review and Meta-analysis.","authors":"Erik Hohmann, Natalie Keough, Rachel M Frank, Scott A Rodeo","doi":"10.1177/03635465241249940","DOIUrl":"https://doi.org/10.1177/03635465241249940","url":null,"abstract":"<p><strong>Background: </strong>Microfragmented adipose tissue has been proposed for intra-articular treatment of knee osteoarthritis. There are little data comparing the outcomes of treatment between microfragmented adipose tissue and other biological treatments.</p><p><strong>Purpose: </strong>To perform a systematic review and meta-analysis comparing microfragmented aspirated fat injections to other orthobiologics, hyaluronic acid, and corticosteroid injections for symptomatic knee osteoarthritis.</p><p><strong>Study design: </strong>Systematic review and meta-analysis; Level of evidence, 2.</p><p><strong>Methods: </strong>A systematic review of the literature was performed to identify pertinent publications in the MEDLINE, Embase, Scopus, and Google Scholar databases, including all level 1 to 3 studies from 2000 to 2023. Validated knee scores (visual analog scale [VAS] for pain, Knee injury and Osteoarthritis Outcome Score [KOOS], Lysholm, International Knee Documentation Committee) were included as outcome measures. Risk of bias was assessed using Cochrane tools. The Grading of Recommendations Assessment, Development and Evaluation system was used to assess the quality of the body of evidence and the modified Coleman Methodology Score was used to assess study quality. Heterogeneity was assessed using χ<sup>2</sup> and <i>I</i><sup>2</sup> statistics.</p><p><strong>Results: </strong>Five studies were included in the analysis. One study had a high risk of bias; 4 studies had some risk of bias. The overall study quality was fair, and the certainty of evidence was low. The pooled estimate for VAS scores did not demonstrate significant differences at 3, 6, and 12 months. The pooled estimate for the KOOS Pain, Symptoms, Activities of Daily Living, Sport and Recreation, and Quality of Life subscales did not demonstrate significant differences at 3, 6, and 12 months.</p><p><strong>Conclusion: </strong>The results of this systematic review and meta-analysis demonstrated that there were no statistically significant differences for both the clinical outcomes and pain scores between microfragmented adipose tissue and other orthobiologics for the treatment of knee osteoarthritis. However, modest study quality, some risk of bias, and low certainty of evidence reduce external validity, and these results must be viewed with some caution.</p>","PeriodicalId":55528,"journal":{"name":"American Journal of Sports Medicine","volume":" ","pages":"3635465241249940"},"PeriodicalIF":4.2,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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American Journal of Sports Medicine
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