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Research on the quality of life of adult patients with cystic fibrosis in Hungary 匈牙利成人囊性纤维化患者的生活质量研究
Q4 Medicine Pub Date : 2016-01-01 DOI: 10.5604/14270994.1206757
T. Tóth, E. Mák, N. Gallo, I. Szabolcs
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引用次数: 2
EFFECT OF DURATION OF INTUBATION ON POST INTUBATION LARYNGEAL CHANGES IN CHILDREN 插管时间对儿童插管后喉部改变的影响
Q4 Medicine Pub Date : 2015-11-30 DOI: 10.5604/14270994.1191783
L. Zawadzka-Głos, Agnieszka Obarska
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引用次数: 1
Respiratory stridor in children due to congenital abnormalities of the great vessels 由于先天性大血管异常引起的儿童呼吸性喘鸣
Q4 Medicine Pub Date : 2015-11-30 DOI: 10.5604/14270994.1191780
Monika Jabłońska-Jesionowska, L. Zawadzka-Głos
Introduction. The respiratory stridor is a clinical symptom of airway obstruction; depending on the location of the pathology we distinguish between inspiratory, expiratory and mixed stridor. Due to the coexistence of congenital airway pathology, stridor is frequently mixed. The most common cause of congenital stenosis of the airways is laryngomalacia, followed by paralysis of the vocal cords and congenital stenosis of the cricoid cartilage. A rare but important causes of the airways narrowing in children are anomalies of the great vessels compressing the trachea and bronchi from the outside. Aim. Aim of this study is to analyze the symptoms in children with respiratory stridor due to anomalies of the great vessels causing pressure on the respiratory tract from the outside. Material and methods. Retrospective study involved a group of 110 children hospitalized in the Pediatric Otolaryngology Department Medical University of Warsaw in 2011-2014 years due to congenital respiratory stridor. During the diagnostics procedures following tests were made: chest X-ray, US of the larynx, US of the brain, X-ray of the esophagus with contrast, echocardiogram and laryngotracheoscopy under general anastesia, chest angio-CT, neurological and cardiac consultation. Results. After analyzing of the cases, there has been found: laryngomalacia in 54, congenital paralysis of the vocal folds in 6, congenital stenosis of the cricoid cartilage in 5, hemangioma of the larynx in 5, laryngeal papilloma in 1, larynx cyst in 5, vascular ring in 31 cases. Identified as vascular rings include: double aortic arch – 5 cases, right aortic arch – 6 cases, anomalies of brachiocephalic trunk – 5 cases, left aortic arch with right lusorian artery – 14 cases, pulmonary sling – 1 case. The clinical symptoms presented by children with rings: respiratory stridor, exercise stridor, silent cry, sleep apnea, cyanosis, dysphagia, recurrent infections of the inferior respiratory tract. The age of children diagnosed with vascular ring ranged from 1 week to 11 years. Conclusions. 1. Congenital respiratory stridor always requires clinical interdisciplinary investigation. 2. Vascular anomalies are a major cause of congenital non-laryngeal respiratory stridor in children of all ages. 3. As a standard the endoscopy of the lower airways, not only the larynx but also trachea should be performed. 4. Lack of lower airways endoscopy in the diagnostic of congenital respiratory stridor can cause lack of recognition of vascular rings. 5. Deleted proper diagnosis of vascular anomalies can caused chronic changes in lower respiratory tract, weight and growth deficiency.
介绍。呼吸性喘鸣是气道阻塞的临床症状;根据病理位置,我们区分吸气、呼气和混合性喘鸣。由于先天性气道病理的共存,喘鸣经常是混合性的。先天性气道狭窄最常见的原因是喉软化,其次是声带麻痹和先天性环状软骨狭窄。儿童气道狭窄的一个罕见但重要的原因是大血管从外部压迫气管和支气管的异常。的目标。本研究的目的是分析大血管异常引起呼吸道外部压力的呼吸性喘鸣患儿的症状。材料和方法。回顾性研究纳入2011-2014年华沙医科大学儿科耳鼻喉科因先天性呼吸性喘鸣住院的110名儿童。在诊断过程中,进行了以下检查:胸部x线、喉部超声、脑部超声、食道x线造影术、超声心动图和喉气管镜、胸部血管ct、神经和心脏会诊。结果。经分析发现:喉软化54例,先天性声带麻痹6例,先天性环状软骨狭窄5例,喉血管瘤5例,喉乳头状瘤1例,喉囊肿5例,血管环31例。经鉴定为血管环的有:双主动脉弓5例,右主动脉弓6例,头臂干异常5例,左主动脉弓伴右lusorian动脉14例,肺悬吊1例。患儿的临床表现为:呼吸性喘鸣、运动性喘鸣、无声哭泣、睡眠呼吸暂停、紫绀、吞咽困难、下呼吸道反复感染。诊断为血管环的儿童年龄从1周至11岁不等。结论:1。先天性呼吸性喘鸣需要临床多学科交叉的研究。2. 血管异常是所有年龄段儿童先天性非喉性呼吸性喘鸣的主要原因。3.作为标准的下气道内窥镜检查,不仅要检查喉,还要检查气管。4. 先天性呼吸性喘鸣诊断缺乏下气道内窥镜检查可导致对血管环的识别不足。5. 删除正确诊断血管异常可引起慢性下呼吸道改变,体重和生长不足。
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引用次数: 0
Primary ciliary dyskinesia: how to diagnose, how to treat 原发性纤毛运动障碍:如何诊断,如何治疗
Q4 Medicine Pub Date : 2015-11-23 DOI: 10.5604/14270994.1191792
Karolina Raczkowska-Bałuda, L. Zawadzka-Głos
characteristics of the syndrome. Underlining the diagnostic and therapeutic difficulties. Pcd symptoms include ards at the age of early – infancy, recurrent lower respiratory tract infections, chronic rhinosinusitis and otitis media, or impaired fertility. Pcd requires differentiation with atypical asthma, bronchiectasis and cystic fibrosis. diagnostic algorithm consist of cascade of tests (brush cytology/bronchoscopic samples, cilia motility evaluation, function and structure assesment with electron microscopy, immunochemical testing, genetic testing) preceded by screening tests (saccharin, measurement nno). 1. the primary ciliary dyskinesia is rarely taking under consideration in the differential diagnosis of chronic/recurrent upper respiratory tract infections. 2. available screening tests do not include target group of patients (< 12 y.o.). 3. no recommendations for the type and methods of obtaining material for testing and methods of its transportation. 4. the basic diagnostic limitation is high cost of a conclusive tests. 5. there is necessity to differentiate primary and secondary ciliary dyskinesia. 6. no general algorithm running patients diagnosed with Pcd – the mandatory introduction of standard therapy.
该综合征的特征。强调诊断和治疗的困难。Pcd的症状包括婴儿期早期的ards,复发性下呼吸道感染,慢性鼻窦炎和中耳炎,或生育能力受损。Pcd需与非典型哮喘、支气管扩张和囊性纤维化鉴别。诊断算法包括级联测试(刷细胞学/支气管镜样本、纤毛运动性评估、电子显微镜功能和结构评估、免疫化学测试、基因测试),然后进行筛选测试(糖精、测量nno)。1. 原发性纤毛运动障碍在慢性/复发性上呼吸道感染的鉴别诊断中很少被考虑。2. 现有的筛查试验不包括目标患者组(< 12岁)。3.没有关于测试材料的类型和获取方法及其运输方法的建议。4. 诊断的基本限制是结论性检查费用高。5. 有必要区分原发性和继发性纤毛运动障碍。6. 没有通用算法运行诊断为Pcd的患者-强制引入标准治疗。
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引用次数: 0
BLEEDING AS THE MAIN COMPLICATION AFTER ADENOIDECTOMY AND ADENOTONSILLOTOMY 出血是腺样体切除术和腺扁桃体切除术后的主要并发症
Q4 Medicine Pub Date : 2015-11-23 DOI: 10.5604/14270994.1191787
T. Ryczer, L. Zawadzka-Głos, Paulina Czarnecka, K. Sobczyk
Introduction. adenoidectomy and adenotonsillotomy are one of the most common surgeries performed in children due to adenoid and tonsils hypertrophy. although the complications after the surgery are quite rare, one of the most common complication is bleeding. Aim. the aim of the study was to analyze the rate of bleeding as the most common early complication (within 24 hours) after adenoidectomy and adenotonsillotomy. the assessed factors were: age, sex, type of surgery, frequency of bleeding and applied surgical treatment, as well as coexisting coagulation disorders. Material and methods. the retrospective analysis of clinical data of 1312 patients hospitalized in the department of pediatric otolaryngology of medical University of Warsaw between January 2011 and december 2012 who underwent adenoidectomy or adenotonsillotomy was done. the objective of the study was to analyze the rate of bleeding as the most common early complication (within 24 hours) after adenoidectomy and adenotonsillotomy. the assessed factors were: age, sex, type of surgery, frequency of bleeding and applied surgical treatment, coexisting coagulation disorders. Results. intense bleeding (p < 0.01) and complications requiring surgical treatment (p < 0.05) occured more often after adenotonsillotomy than after adenotomy. in patients with coexisting coagulation disorders early complications were observed more often (p < 0.01). patients from specific age groups did not demonstrate statisticaly relevant higher complication rate, nor did male versus female group (p > 0.05). Conclusions. the study showed that intense bleeding and complications requiring surgical treatment occured more often after adenotonsillotomy than after adenotomy. patients with coagulation disorders were more likely to have intense intraor postoperatively bleeding. the age and the sex of the patient did not correlate with the higher bleeding rate.
介绍。由于腺样体和扁桃体肥大,腺样体切除术和腺扁桃体切除术是儿童最常见的手术之一。虽然手术后的并发症很少见,但最常见的并发症之一是出血。的目标。本研究的目的是分析出血作为腺样体切除术和腺扁桃体切除术后最常见的早期并发症(24小时内)的发生率。评估的因素包括:年龄、性别、手术类型、出血频率和应用手术治疗,以及共存的凝血障碍。材料和方法。回顾性分析2011年1月至2012年12月在华沙医科大学儿科耳鼻喉科接受腺样体切除术或腺扁桃体切除术的1312例患者的临床资料。本研究的目的是分析出血作为腺样体切除术和腺扁桃体切除术后最常见的早期并发症(24小时内)的发生率。评估的因素包括:年龄、性别、手术类型、出血频率和应用手术治疗、并存凝血障碍。结果。腺扁桃体切除术后大出血(p < 0.01)和并发症(p < 0.05)发生率高于腺扁桃体切除术后。合并凝血功能障碍患者早期并发症发生率较高(p < 0.01)。特定年龄组患者并发症发生率无统计学差异,男女组无统计学差异(p < 0.05)。结论。研究表明,与腺扁桃体切开术相比,腺扁桃体切开术后更容易出现大出血和需要手术治疗的并发症。有凝血功能障碍的患者更容易出现严重的术中或术后出血。患者的年龄和性别与较高的出血率无关。
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引用次数: 6
Lingual tonsil hypertrophy as a cause of obstructive sleep apnea syndrome – case report 舌扁桃体肥大引起阻塞性睡眠呼吸暂停综合征1例报告
Q4 Medicine Pub Date : 2015-11-23 DOI: 10.5604/14270994.1191789
Małgorzata Badełek-Izdebska, M. Dębska, L. Zawadzka-Głos
the hypertrophy of the lingual tonsil (Lth) could be the cause of obstructive sleep apnea in children. this disorder may cause obstructive sleep apnea (osa) and also may lead to a life-threatening obstruction of the upper airway. Lingual tonsil hypertrophy is more frequently described in adults. Lth often occurs in children with prior palatine tonsillectomies or adenoidectomies. diagnosis of lingual tonsil hypertrophy in patients with osa requires a careful ent examination by advanced technologic methods. the sleep apnea is successfully treated by lingual tonsillectomy, with or without tracheotomy. tracheostomy allows the obstructive airway with postoperative oedema to be bypassed. in this study we present the case of a child with persistent syndroms of a sleep apnea. patient underwent six adenotonsillectomies in the past. ent examination and ct scans showed that symptoms of osa were caused by lingual tonsil hypertrophy. patient was treated with a lingual tonsillectomy with tracheotomy and it was an effective treatment for this case.
舌扁桃体肥大(Lth)可能是儿童阻塞性睡眠呼吸暂停的原因。这种疾病可能导致阻塞性睡眠呼吸暂停(osa),也可能导致危及生命的上呼吸道阻塞。舌扁桃体肥大更常见于成人。Lth常发生于既往做过腭扁桃体切除或腺样体切除的儿童。阻塞性睡眠呼吸暂停患者舌扁桃体肥大的诊断需要用先进的技术方法进行仔细的检查。睡眠呼吸暂停是成功的治疗舌扁桃体切除术,有或没有气管切开术。气管造口术可以绕过术后水肿的梗阻性气道。在这项研究中,我们提出的情况下,儿童与持续综合征的睡眠呼吸暂停。患者过去曾做过6次腺扁桃体切除术。耳鼻喉检查和ct扫描显示呼吸暂停症状是由舌扁桃体肥大引起的。患者行舌扁桃体切除加气管切开术,是治疗此病的有效方法。
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引用次数: 0
Difficulties and opportunities related to the nutrition of cancer patients 癌症患者营养相关的困难与机遇
Q4 Medicine Pub Date : 2015-11-23 DOI: 10.5604/14270994.1191795
N. Gallo, M. Varga, A. Molnár, Róbertné Csajbók, Katalin Tátrai-Németh, E. Pálfi
1Department of Dietetics and Nutrition Sciences, Faculty of Health Sciences, Semmelweis University, Budapest, Hungary Head of Department: prof. Katalin Tátrai-Németh, PhD 2Department of Dietetics, Szent Imre Teaching Hospital, Budapest, Hungary Head of Department: Kyri Herscoviciné Vass, Dietitian 3Health Sciences Research, Doctoral School of Pathological Sciences, School of PhD Studies, Semmelweis University, Budapest, Hungary Head of Health Sciences Research: prof. Gyula Domján, MD, PhD
1匈牙利布达佩斯Semmelweis大学健康科学学院营养与营养学系系主任:Katalin教授Tátrai-Németh,博士2匈牙利布达佩斯Szent Imre教学医院营养学系系主任:Kyri herscovicinvevass,营养师3匈牙利布达佩斯Semmelweis大学博士学院病理科学博士学院健康科学研究系主任:Gyula教授Domján,医学博士,博士
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引用次数: 0
DETECTION OF NEURAMINIDASE-INHIBITING ANTIBODIES FOR MEASUREMENT OF INFLUENZA VACCINE IMMUNOGENICITY 检测神经氨酸酶抑制抗体测定流感疫苗免疫原性
Q4 Medicine Pub Date : 2015-11-23 DOI: 10.5604/14270994.1191796
M. Rózsa, I. Jankovics, I. Visontai, I. Barcs
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引用次数: 1
Changes in smoking-related health knowledge and smoking status of Hungarian adolescents 匈牙利青少年吸烟相关健康知识和吸烟状况的变化
Q4 Medicine Pub Date : 2015-11-23 DOI: 10.5604/14270994.1191794
M. Pénzes, P. Balázs, K. Foley
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引用次数: 1
Treatment subungual melanoma in foot – case report 治疗足部的甲下黑色素瘤
Q4 Medicine Pub Date : 2015-07-20 DOI: 10.5604/14270994.1179837
K. Wroński, Z. Masłowski, L. Frąckowiak, P. Stefaniak
subungual melanoma is rare disease and has worse prognosis than cutaneous melanoma in other places. This type of melanoma is observed accounting for 1 to 3% of all cutaneous melanoma in caucasians. it is estimated that 1 of every 39 people in the western countries will be diagnosed melanoma of the skin during lifetime. The number of patients with skin melanoma is increasing and cause a growing economic problem for health care. Dermoscopy or videos dermoscopy is the basis for the initial diagnosis of melanoma of the skin. sensitivity dermoscopy is up to 96.3% and the specificity up to 94.2%. The literature on dermoscopic examination of the nails is limited to very few published observations. large number of information is available on dermoscopy of pigmented lesions elsewhere on the body skin. Dermoscopy can help clinicians accurately decide if a biopsy of the nail apparatus is necessary in cases of melanoma suspicious. surgical biopsy of the lesion is the gold standard for diagnosis subungual melanoma. The “gold standard” of treatment is surgical amputation and sentinel lymph node biopsy. in this article the authors presented a case of a woman who was admitted to the hospital because of subungual melanoma in foot. The patient underwent amputation of toe with sentinel lymph node biopsy and in the second day after surgery was discharged home.
甲下黑色素瘤是一种罕见的疾病,预后比其他部位的皮肤黑色素瘤差。这种类型的黑色素瘤占白种人皮肤黑色素瘤的1%至3%。据估计,在西方国家,每39人中就有1人在一生中被诊断为皮肤黑色素瘤。皮肤黑色素瘤患者的数量正在增加,这给医疗保健带来了越来越大的经济问题。皮肤镜检查或视频皮肤镜检查是皮肤黑色素瘤初步诊断的基础。皮肤镜敏感性达96.3%,特异性达94.2%。关于指甲皮肤镜检查的文献仅限于极少数发表的观察结果。大量的信息是可用的皮肤镜检查色素病变在身体皮肤的其他地方。皮肤镜检查可以帮助临床医生准确地决定是否有必要在可疑的黑色素瘤病例中进行指甲活检。手术活检是诊断甲下黑色素瘤的金标准。治疗的“金标准”是手术截肢和前哨淋巴结活检。在这篇文章中,作者提出了一个病例的妇女谁是入院的医院,因为脚趾骨下黑色素瘤。患者接受了前哨淋巴结活检的脚趾截肢手术,术后第二天出院回家。
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引用次数: 1
期刊
New Medicine
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