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adenoid and tonsils hypertrophy − symptoms and treatment 腺样体和扁桃体肥大-症状和治疗
Q4 Medicine Pub Date : 2016-12-23 DOI: 10.5604/14270994.1228134
Iwona Łapińska, L. Zawadzka-Głos
Introduction. Adenoid and tonsil hypertrophy is widespread in the pediatric population, affecting primarily younger children, aged 3 to 6 years. in 1884, a German pathologist, von Waldeyer-hartz, first described clusters of lymphoid tissue in mucosa of the throat, which he named facial lymphatic ring, known today as Waldeyer’s tonsillar ring. Waldeyer’s ring plays a significant role in the development of immune response by allowing the contact of the immune system with multiple antigens and thus, enabling the development of the specific immunological response. the main points of contact of the body with the external environment are the mucous membranes of the digestive and respiratory systems. Waldeyer’s ring, being at the opening of both systems, has a particular role in the development of immune response, especially during the first years of life. Aim. the aim of the study was to analyze the symptoms presented by children hospitalized in the Clinic of pediatric otolaryngology of the medical University of Warsaw that had been qualified for the surgical removal of the adenoid and/or tonsils. Material and methods. All the patients underwent physical examination, and filled in a survey. the study included 59 hospitalized patients, 2 of which refused to disclose the symptoms associated with adenoid and tonsil hypertrophy that was diagnosed in them. Results. the study involved 59 children aged from 2 to 13 years old. the mean age was 6.2 years. the patients were qualified for adenoidectomy or adenotonsillotomy. in 26 cases, at least one of the parents of the patient smoked in the presence of the child. 28 patients reported nasal obstruction, and 29 denied such symptoms. As many as 41 patients (71.9%) reported snoring during sleep. 45 patients (78.9%) breathed through the mouth. Based on the medical history collected from the parents, 22 patients (37.3%) had upper respiratory tract infection at least once a month, 7 patients – every two weeks, 9 – every two months, 15 – every three months, 5 – every 6 months, and one – once a year. Conclusions. 1. the most common symptom in pediatric patients with adenoid and tonsil hypertrophy is snoring. 2. 1/3 of the children with enlarged tonsils is diagnosed with allergies. 3. Almost 45% of children with hypertrophy of the tonsils are exposed to tobacco smoke. 4. Children with enlarged tonsils have upper respiratory tract infections on average once a month.
介绍。腺样体和扁桃体肥大在儿科人群中很普遍,主要影响3至6岁的幼儿。1884年,德国病理学家冯·瓦尔代耶-哈茨(von Waldeyer-hartz)首次描述了喉咙粘膜中的淋巴组织集群,他将其命名为面部淋巴环,即今天的瓦尔代耶扁桃体环。Waldeyer 's ring通过允许免疫系统与多种抗原接触,从而使特异性免疫反应的发生,在免疫反应的发展中起着重要作用。人体与外界环境的主要接触点是消化系统和呼吸系统的粘膜。瓦尔德耶氏环位于两个系统的开口,在免疫反应的发展中起着特殊的作用,特别是在生命的最初几年。的目标。本研究的目的是分析在华沙医科大学儿科耳鼻喉科诊所住院的符合手术切除腺样体和/或扁桃体资格的儿童所出现的症状。材料和方法。所有患者均接受体格检查,并填写调查问卷。本研究纳入59例住院患者,其中2例拒绝透露诊断出的与腺样体和扁桃体肥大相关的症状。结果。这项研究涉及59名2至13岁的儿童。平均年龄为6.2岁。患者符合腺样体切除术或腺扁桃体切除术的条件。在26例中,患者的父母中至少有一方在孩子面前吸烟。28例报告鼻塞,29例否认有此类症状。多达41名患者(71.9%)报告在睡眠中打鼾。45例(78.9%)患者通过口腔呼吸。根据父母的病史,22例(37.3%)患者每月至少有一次上呼吸道感染,7例(每两周),9例(每两个月),15例(每三个月),5例(每6个月),1例(每年)。结论:1。儿童腺样体和扁桃体肥大患者最常见的症状是打鼾。2. 三分之一扁桃体肿大的儿童被诊断为过敏。3.近45%的扁桃体肥大儿童暴露于烟草烟雾中。4. 扁桃体肿大的儿童平均每月有一次上呼吸道感染。
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引用次数: 13
Cardiovascular screening program in children in Budapest 布达佩斯儿童心血管筛查项目
Q4 Medicine Pub Date : 2016-12-23 DOI: 10.5604/14270994.1228165
J. Kormos-Tasi, E. gácsi, F. Tóth, A. Czinner, L. Szabó
IntroductIon obesity and hypertension are two most important risk factors for cardiovascular diseases (1, 2). obesity is one of the most common health problems of the developed countries. the prevalence is increasing among adults and children alike. In Hungary, the prevalence in children is 9-10%. In 1998, WHo (World Health organization) classified obesity as a disease. obesity, and other metabolic, endocrine and musculoskeletal diseases that are caused by obesity are seen as one of the biggest public health-related problem nowadays. obesity increases the morbidity and mortality in all the populations.
肥胖和高血压是心血管疾病的两个最重要的危险因素(1,2)。肥胖是发达国家最常见的健康问题之一。成人和儿童的患病率都在上升。在匈牙利,儿童患病率为9-10%。1998年,世界卫生组织将肥胖列为一种疾病。肥胖以及其他由肥胖引起的代谢、内分泌和肌肉骨骼疾病被视为当今最大的公共健康问题之一。肥胖增加了所有人群的发病率和死亡率。
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引用次数: 0
diFFiCUlties, heAlth proBlems And proFessionAl sUpport oF diVorCed FAthers liVinG sepArAtely From their Children – eXperienCes in hUnGAry 与子女分开生活的离异父亲的困难、健康问题和专业支持——匈牙利的经验
Q4 Medicine Pub Date : 2016-12-23 DOI: 10.5604/14270994.1228182
Z. Kiss, B. Keserü, Magdolna Sinka, I. Krémer
1Institute for Health Promotion and Clinical Methodology, Department of Clinical Studies, Semmelweis University Faculty of Health Sciences, Budapest, Hungary Head of Department: Professor Klára Gadó, MD, PhD 2Institute for Health Promotion and Clinical Methodology, Department for Epidemiology, Semmelweis University Faculty of Health Sciences, Budapest, Hungary Head of Department: István Barcs, PhD 3Institute of Applied Health Sciences, Department of Clinical Studies in Obstetrics and Gynaecology, Semmelweis University Faculty of Health Sciences, Budapest, Hungary Head of Department: Professor János Rigó, MD, PhD 1, 2, 3Semmelweis University Faculty of Health Sciences, Budapest, Hungary Head of Faculty: Professor Zoltán Zsolt Nagy, MD, PhD
1匈牙利布达佩斯塞梅尔魏斯大学卫生科学学院临床研究系健康促进和临床方法学研究所系主任:教授Klára Gadó,医学博士,博士2匈牙利布达佩斯塞梅尔魏斯大学卫生科学学院流行病学系健康促进和临床方法学研究所系主任:István Barcs,博士3匈牙利布达佩斯塞梅尔韦斯大学健康科学学院应用健康科学研究所妇产科临床研究系系主任:教授János Rigó医学博士1,2,3匈牙利布达佩斯塞梅尔韦斯大学健康科学学院系主任:教授Zoltán Zsolt Nagy医学博士,博士
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引用次数: 0
CompArAtiVe stUdy oF hyGiene hABits in three diFFerent GroUps in hUnGAry 匈牙利三个不同人群卫生习惯的比较研究
Q4 Medicine Pub Date : 2016-12-23 DOI: 10.5604/14270994.1228169
csenge Földvári-nagy, Kincső Földvári-nagy, D. Módos, K. Lenti
1Cambridge Centre for Sixth-form Studies, Cambridge, United Kingdom Principal: Stuart Nicholson 2Illyés Gyula High School, Budaörs, Hungary Head of School: Péter Árendás 3Trefort Ágoston High School, Budapest, Hungary Head of School: Zoltán Csapodi 4Department of Morphology and Physiology, Faculty of Health Sciences, Semmelweis University, Budapest, Hungary Head of Department: Professor Gabriella Dörnyei, PhD
1英国剑桥大学六年级研究中心校长:斯图尔特·尼科尔森2匈牙利伊利姆斯·乔拉高中,Budaörs校长:p Árendás 3Trefort Ágoston匈牙利布达佩斯高中校长:Zoltán Csapodi 4匈牙利布达佩斯塞梅维什大学健康科学学院形态与生理学系系主任:Gabriella教授Dörnyei博士
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引用次数: 1
the Change of Corneal SurfaCe temperature during SurfaCe refraCtiVe SurgiCal proCedureS performed uSing exCimer laSerS with different repetitiVe frequenCieS 使用不同重复频率的准分子激光进行表面屈光手术过程中角膜表面温度的变化
Q4 Medicine Pub Date : 2016-09-29 DOI: 10.5604/14270994.1222609
Csaba Szekrényesi, Gábor L Sándor, A. Gyenes, Huba J. M. Kiss, T. Filkorn, Z. Nagy
Intoduction. refractive surgery is still one of the most frequently performed procedures in ophthalmology. millions of patients every year are operated with surface lasers as well as with deep or lamellar lasers. The operational technique and tools are constantly improving. Aim. To examine the changes in the temperature of the corneal surface during refractive surgery procedures performed using different types of excimer lasers. Material and methods. 150 eyes of 111 patients were included in the study. The corneal surface temperature was measured with a calibrated eBro Tlc730 infrared thermometer (wTw gmBh, germany) before photorefractive keratectomy (prK), after epithelial removal and immediately after finishing the procedure. The average myopic correction was -3.9 ± 1.9 dpt (ranging from -2.5 dpt to -6.5 dpt). The average age of the patients was 25 ± 3.3 years. Results. using anova variance analysis, a statistically significant difference in the change of the temperature was found between different laser platforms. with the post hoc Bonferroni correction, a significant difference between the mel 80 (carl Zeiss meditec, Jena, germany) and the two other analyzed excimer lasers, mel 70 (carl Zeiss meditec, Jena, germany) and wavelight allegretto 400 (alcon wavelight, erlangen, germany), was found. There was no statistically significant difference between the wavelight allegretto and mel 70 excimer lasers. Conclusions. The moderate cooling effect of the different excimer laser platforms might be related to different airflow systems used in the models. it seems that the rise in the surface temperature is not a causative factor of postoperative subepithelial corneal haze when the procedure is performed with lasers using frequencies lower or equal to 400 hz.
Intoduction。屈光手术仍然是眼科最常用的手术之一。每年有数以百万计的患者使用表面激光以及深层或层状激光进行手术。操作技术和工具在不断改进。的目标。目的:观察不同类型准分子激光在屈光手术过程中角膜表面温度的变化。材料和方法。研究纳入了111名患者的150只眼睛。在光屈光性角膜切除术(prK)前、上皮切除后和手术结束后立即用校准的eBro Tlc730红外温度计(wTw gmBh, germany)测量角膜表面温度。平均近视矫正为-3.9±1.9 dpt (-2.5 ~ -6.5 dpt)。患者平均年龄25±3.3岁。结果。通过方差分析,发现不同激光平台之间的温度变化具有统计学意义。通过后期Bonferroni校正,发现mel 80(卡尔蔡司meditec,耶拿,德国)和mel 70(卡尔蔡司meditec,耶拿,德国)和allegretto 400 (alcon waveight,埃尔兰根,德国)这两种被分析的准分子激光器之间存在显著差异。在小光波快板和mel 70准分子激光之间没有统计学上的显著差异。结论。不同准分子激光平台的适度冷却效果可能与模型中使用的不同气流系统有关。当使用频率低于或等于400赫兹的激光进行手术时,表面温度的升高似乎不是术后上皮下角膜雾霭的原因。
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引用次数: 2
preValenCe of rem BehaVioral diSorder and rem Sleep without atonia in patientS Suffering from parKinSon’S diSeaSe 帕金森病患者快速眼动行为障碍和无张力快速眼动睡眠的患病率
Q4 Medicine Pub Date : 2016-09-29 DOI: 10.5604/14270994.1222610
Z. Szakács, T. seres, Éva Kellős, M. Simon, A. Horváth, V. Fay, Jelena Karaszova, A. Kontra, olívia lalátka, M. Csóka, G. Domján
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引用次数: 1
Klotho protein proteCtS againSt aging and niCotine-induCed ChroniC Cellular StreSS Klotho蛋白防止衰老和尼古丁诱导的慢性细胞应激
Q4 Medicine Pub Date : 2016-09-29 DOI: 10.5604/14270994.1222604
Daniel Piątek, Emilia Migryt, Kamila Tuzim, Joanna Szydełko, A. Boguszewska-Czubara
From 1997, when Klotho protein was first discovered and named “the anti-aging hormone”, scientists have been thoroughly investigating its biological properties. this protein plays an important role in numerous metabolic pathways that contribute to slower ageing processes. the prevalence of neurodegenerative diseases, impairment of cognitive functions and chronic stress increases with age. additional factors, such as nicotine, rosiglitazone, statins, blood-pressure lowering drugs, calcitriol, magnesium, chronic psychosocial stress and aerobic exercises have an influence on Klotho protein plasma concentration. the research on proteins that increase Klotho plasma levels is important because of broad range of biological processes in which Klotho is engaged. Further studies on this substance could result in new possibilities of treatment for several common diseases.
自1997年Klotho蛋白首次被发现并被命名为“抗衰老激素”以来,科学家们一直在深入研究它的生物学特性。这种蛋白质在许多代谢途径中起着重要作用,有助于减缓衰老过程。神经退行性疾病、认知功能障碍和慢性压力的患病率随着年龄的增长而增加。其他因素,如尼古丁、罗格列酮、他汀类药物、降血压药物、骨化三醇、镁、慢性心理社会压力和有氧运动对Klotho蛋白血浆浓度有影响。研究提高Klotho血浆水平的蛋白质是很重要的,因为Klotho参与了广泛的生物过程。对这种物质的进一步研究可能会为几种常见疾病的治疗带来新的可能性。
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引用次数: 0
ViewS of StudentS of puBliC health inSpeCtor training on further StudieS and employment opportunitieS 公共卫生督察学员对进修及就业机会的看法
Q4 Medicine Pub Date : 2016-09-29 DOI: 10.5604/14270994.1222613
Magdolna Sinka, I. Barcs, G. Domján, Zsuzsanna Kiss Soósnè
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引用次数: 1
Safety of treatment and dietary Supplementation with dioSmin in daily doSeS up to 2000 mg a day 治疗和膳食补充的安全性,每日剂量高达2000mg /天
Q4 Medicine Pub Date : 2016-09-29 DOI: 10.5604/14270994.1222599
Agnieszka Staniewska
Introduction. diosmin is used to treat and alleviate the symptoms of venous insufficiency and haemorrhoids. diosmin-containing medicinal products have been available in poland since the 1990s with the status of drugs available on prescription in the form of flavonoid fraction containing diosmin, as a form subjected to micronisation or nonmicronised. for several years now, diosmin has been present on the pharmaceutical market in the form of over-the-counter medicines (otC), and dietary supplements containing diosmin are available not only in pharmacies, but also in other outlets. great availability of diosmin raises questions about the safety of a treatment without medical or pharmacist’s supervision. the safety of diosmin use in a daily dose of 2000 mg was confirmed in a double-blind, controlled placebo, randomised, three-arm and parallel, phase iii to evaluate the efficacy and safety of diosmin administered for 4 months in the treatment of cellulite. Aim. the aim of the study was to observe the efficacy and safety of micronised diosmin therapy used in a daily dose of 1000 and 2000 mg for a period of four months. Material and methods. the trial involved 327 patients aged 18 to 55 (mean 37.28, standard deviation of 8.587) meeting the inclusion criteria and not meeting the exclusion criteria. the safety analysis includes and shows in a table the measured parameters immediately prior to the first dose, after 2 and 4 months of therapy. Results. no statistically significant deviations from the standard condition in the following parameters present: complete blood count with differential, fibrinogen concentrations, alanine and aspartate transaminase concentration, urea and creatinine concentration, urinalysis. the therapy did not affect the value of systolic and diastolic blood pressure. no significant adverse actions in the studied groups. Conclusions. the results of a clinical trial cited in this work support the use of micronised diosmin in doses up to 2000 mg per day.
介绍。地奥司明用于治疗和缓解静脉功能不全和痔疮的症状。自20世纪90年代以来,波兰已提供含薯蓣皂苷的医药产品,其处方药物状态为含有薯蓣皂苷的类黄酮部分,作为微粉化或非微粉化的形式。几年来,戴奥司明已经以非处方药(otC)的形式出现在医药市场上,含有戴奥司明的膳食补充剂不仅在药店,而且在其他渠道也可以买到。在没有医生或药剂师监督的情况下,地奥明的大量可用性引发了对治疗安全性的质疑。在一项双盲、对照安慰剂、随机、三组平行、iii期研究中,日剂量为2000mg的地奥司明的安全性得到了证实,该研究旨在评估地奥司明治疗脂肪团4个月的疗效和安全性。的目标。这项研究的目的是观察在4个月的时间里,每日剂量为1000和2000毫克的微型二恶英治疗的疗效和安全性。材料和方法。试验纳入327例符合纳入标准和不符合排除标准的患者,年龄为18 ~ 55岁(平均37.28,标准差8.587)。安全性分析包括并在表格中显示了在第一次给药前、治疗2个月和4个月后测量的参数。结果。以下参数与标准条件无统计学差异:全血细胞计数差异、纤维蛋白原浓度、丙氨酸和天冬氨酸转氨酶浓度、尿素和肌酐浓度、尿液分析。治疗不影响收缩压和舒张压值。在研究组中没有明显的不良反应。结论。这项工作中引用的一项临床试验结果支持每天使用高达2000毫克的微细化地奥米明。
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引用次数: 2
pSyChiatriC diSorderS aS a riSK faCtor for warthin’S tumor 精神疾病是沃辛肿瘤的危险因素
Q4 Medicine Pub Date : 2016-09-29 DOI: 10.5604/14270994.1222601
K. Wroński, J. Kaczor, Z. Masłowski, L. Frąckowiak, Michal Frackowiak
1Department of Surgical Oncology, Hospital Ministry of Internal Affairs with Warmia and Mazury Oncology Centre, Olsztyn, Poland Head of Department: Andrzej Lachowski, MD 2Department of Public Health and Epidemiology, University of Warmia and Mazury in Olsztyn, Poland Head of Department: Professor Anna Abramczyk, MD, PhD 3Faculty of Medicine, Medical University in Gdańsk, Poland Dean of University: Professor Janusz Moryś, MD, PhD
1波兰奥尔什廷瓦姆尼亚和马祖里内务部肿瘤中心外科肿瘤科系主任:Andrzej Lachowski医学博士2波兰奥尔什廷瓦姆尼亚和马祖里大学公共卫生与流行病学系主任:Anna Abramczyk教授医学博士3波兰Gdańsk医科大学医学院院长:Janusz moryzov教授医学博士
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引用次数: 0
期刊
New Medicine
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