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Root coverage using recombinant human fibroblast growth factor-2 treated connective tissue graft: Case studies. 使用重组人成纤维细胞生长因子-2处理结缔组织移植物的根覆盖:案例研究。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-02 DOI: 10.1002/cap.10323
Guo-Liang Cheng, Satoru Urano, Yu-Chang Wu, Rami Alsabbagh, Hsun-Liang Chan
<p><strong>Background: </strong>This case study documents the application of connective tissue graft (CTG) combined with biologics on treating challenging gingival recession cases of mandibular anterior teeth caused by orthodontic tooth movement.</p><p><strong>Methods: </strong>Three patients presented for periodontal consultation due to gingival recession resulting from orthodontic treatment. The patients reported esthetic concerns and discomfort while brushing their teeth. The gingival defects were mainly localized to the mandibular incisors, with recession depths ranging from 1 to 5 mm and complicated by loss of papilla and a lack of keratinized tissue. RT2 gingival recession with thin gingival phenotype was confirmed. All gingival defects were managed using recombinant human fibroblast growth factor-2 (rhFGF-2) treated CTG. The recipient sites were prepared using tunnel or modified tunnel techniques. CTG harvested from the hard palate was treated with rhFGF-2 for 3 min then inserted into the prepared tunnel space and secured with a sling suture technique for coronal advancement.</p><p><strong>Results: </strong>The three patients were followed from 6 months to 6 years. Generally, initial wound healing was within normal limits during the first several weeks. The recession defects were successfully covered, achieving a nearly 100% root coverage rate. The combination of CTG+rhFGF-2 resulted in satisfying recession depth reduction, papilla augmentation, and gain of keratinized tissue. Patients were satisfied with the improvement of esthetics and function.</p><p><strong>Conclusions: </strong>This innovative approach demonstrates that rhFGF-2 treated CTG significantly improves the mucogingival problems caused by orthodontic treatment. Successful phenotype modification provides functional and esthetic improvement as well as long-term stability of periodontal health.</p><p><strong>Plain language summary: </strong>Receding gums are a common complication after wearing dental braces, which sometimes can be severe if the initial gum tissue is thin. This complication could cause tooth sensitivity, discomfort when brushing, and compromised esthetics. To regenerate the lost tissue, a connective tissue graft (CTG) harvested from the roof of the oral cavity is very commonly used as a transplantation option with substantial supporting evidence. However, for cases of severe gum recession, CTGs still have limitations on treatment. Therefore, clinicians and researchers are dedicated to improving treatment outcomes by adding biomaterials to the graft to enhance clinical outcomes. A relatively new material, recombinant human fibroblast growth factor-2 (rhFGF-2), has proven to be effective in periodontal regenerative treatments and could potentially augment the soft tissue regenerative capacity of the graft. This case study documents the application of rhFGF-2 in combination with CTGs for treating severe gum recession in three patients. The treatment results demonstr
背景:本病例研究记录了结缔组织移植联合生物制剂治疗正畸牙齿移动引起的下颌前牙挑战性牙龈退缩病例。方法:对3例因正畸治疗导致牙龈萎缩的患者进行牙周会诊。患者报告了刷牙时的审美问题和不适。牙龈缺损主要局限于下颌切牙,退缩深度1 ~ 5mm,并伴有乳突缺失和角化组织缺失。证实RT2牙龈萎缩伴薄牙龈表型。所有牙龈缺损均采用重组人成纤维细胞生长因子-2 (rhFGF-2)处理CTG。采用隧道或改良隧道技术制备受体位点。硬腭CTG用rhFGF-2处理3分钟,然后插入准备好的隧道空间,用吊带缝合技术固定冠状推进。结果:3例患者随访6个月至6年。一般来说,最初的几周内伤口愈合在正常范围内。成功地覆盖了衰退缺陷,实现了接近100%的根覆盖率。CTG+rhFGF-2联合使用可使退缩深度减小,乳头增大,角质化组织增加。患者对美观和功能的改善感到满意。结论:该创新方法表明rhFGF-2治疗CTG可显著改善正畸治疗引起的粘膜牙龈问题。成功的表型修饰提供了功能和美观的改善以及牙周健康的长期稳定性。简单的语言总结:牙龈萎缩是戴牙套后常见的并发症,如果最初的牙龈组织很薄,有时会很严重。这种并发症会导致牙齿敏感,刷牙时不舒服,美观受损。为了再生失去的组织,从口腔顶部采集结缔组织移植物(CTG)是一种非常常用的移植选择,有大量的支持证据。然而,对于严重牙龈萎缩的病例,CTGs的治疗仍然有局限性。因此,临床医生和研究人员致力于通过在移植物中添加生物材料来改善治疗效果,以提高临床效果。重组人成纤维细胞生长因子-2 (rhFGF-2)是一种相对较新的材料,已被证明在牙周再生治疗中有效,并可能潜在地增强移植物的软组织再生能力。本案例研究记录了rhFGF-2联合CTGs治疗3例严重牙龈萎缩患者的应用。治疗结果显示显著改善,随访数据从6个月到6年不等。这些改进包括覆盖暴露的牙根表面,牙间组织的再生和牙龈组织的增厚。患者对这种方法在功能和美观方面产生的积极变化感到满意。
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引用次数: 0
Master Clinician Editorial. 硕士临床医师编辑。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-28 DOI: 10.1002/cap.70034
Myron Nevins, David M Kim
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引用次数: 0
Management of peri-implant soft tissue dehiscence with combined prosthetic-surgical approach: A case report. 假体-外科联合入路治疗种植体周围软组织裂开1例。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-19 DOI: 10.1002/cap.70039
Omran Bishbish Zeino, Yoon Jeong Kim

Background: This case report presents the management of an esthetic complication of a peri-implant soft tissue dehiscence (PSTD) through a combined prosthetic-surgical approach.

Methods and results: A 53-year-old healthy Hispanic male presented to our practice for the treatment of an implant esthetic complication. A diagnosis of PSTD class III C was established. The abutment and crown were first modified to accommodate the tissue graft and support the coronally advanced flap (CAF). Then, a CAF with tuberosity connective tissue graft was performed. A definitive abutment and crown were fabricated 8 months after healing. Significant improvement of the PSTD, improvement of the peri-implant soft tissue dimensions, and patient satisfaction have been achieved.

Conclusion: A combined prosthetic-surgical approach constitutes a valid treatment modality for PSTD class III C where there is abundant interproximal tissue available.

Key points: Integrated treatment approach: A combined prosthetic-surgical technique offers an effective solution for managing peri-implant soft tissue dehiscence (PSTD), ensuring improved tissue thickness and stability.

Clinical considerations: The bucco-lingual implant position and interproximal tissue quality are key factors in determining the optimal treatment strategy. Predictable outcomes: Coronally advanced flap combined with connective tissue grafting can enhance esthetic and functional results for management of PSTD.

Plain language summary: Peri-implant soft tissue complications can affect both the function and appearance of dental implants. This case study explores an approach that combines surgical and prosthetic techniques to improve the gingival tissue surrounding an implant. A 53-year-old patient had an esthetic concern due to gum recession around his implant. To correct this, his dental crown and abutment were adjusted. Then, a gingival grafting procedure to reposition the gingival tissue and enhance its thickness was performed. After healing for eight months, the implant was permanently restored with a final crown. The results showed significant improvements in gingival tissue health, thickness, and appearance, leading to patient satisfaction. The findings highlight how combining surgical techniques with prosthetic adjustments can help manage similar cases, offering a predictable solution to improve both the appearance and stability of dental implants.

背景:本病例报告介绍了通过假体-外科联合入路治疗种植体周围软组织裂开(PSTD)的美学并发症。方法和结果:一名53岁的西班牙裔健康男性向我们介绍了种植体美学并发症的治疗。诊断为PSTD III C级。首先对基台和冠进行改良,以容纳组织移植物并支持冠状推进瓣(CAF)。然后行CAF合并结节结缔组织移植物。修复后8个月制作最终基台和冠。PSTD显著改善,种植体周围软组织尺寸改善,患者满意度提高。结论:对于近端间组织丰富的III级PSTD,假体-手术联合入路是一种有效的治疗方式。综合治疗方法:假体-外科联合技术为治疗种植体周围软组织开裂(PSTD)提供了有效的解决方案,确保了组织厚度和稳定性的提高。临床考虑:颊舌种植体位置和近端间组织质量是决定最佳治疗策略的关键因素。可预测的结果:冠状进展皮瓣联合结缔组织移植可以提高治疗PSTD的美观和功能效果。摘要:种植体周围软组织并发症会影响种植体的功能和外观。本案例研究探讨了一种结合手术和假体技术来改善种植体周围牙龈组织的方法。一名53岁的患者由于种植体周围的牙龈萎缩而担心美观。为了纠正这个问题,他调整了牙冠和基牙。然后,进行牙龈移植手术,以重新定位牙龈组织并增加其厚度。愈合8个月后,种植体被永久性地修复,并有一个最终的冠。结果显示牙龈组织健康、厚度和外观显著改善,患者满意。研究结果强调了如何将手术技术与假体调整相结合,可以帮助处理类似的病例,提供可预测的解决方案,以改善牙种植体的外观和稳定性。
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引用次数: 0
Unusual co-occurrence of cheilitis granulomatosa and plasma cell gingivitis: A case report. 阴唇炎、肉芽肿与浆细胞性牙龈炎罕见共发1例。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-30 DOI: 10.1002/cap.70016
Lata Goyal, Mehak Gupta, Gargi Kapatia, Amanurrahman Zubair Ahemad, Shipra Gupta

Background: Cheilitis granulomatosa (CG) and plasma cell gingivitis (PCG) are uncommon inflammatory conditions affecting the oral regions. CG manifests as chronic lip swelling with granulomatous inflammation, while PCG presents as erythematous gingiva or gingival enlargement linked to hypersensitivity reactions. Their simultaneous occurrence is exceedingly rare, posing diagnostic and therapeutic challenges.

Methods: A 32-year-old woman presented with recurrent upper lip swelling and gingival enlargement. Clinical examination revealed erythematous gingiva with a cobblestone texture and angular cheilitis. Biopsies confirmed orofacial granulomatosis with epithelioid granulomas and PCG with plasma cell infiltration. Management consists of diet modification and periodontal intervention. Postoperative outcomes demonstrated significant improvement, and allergen elimination strategies were implemented to reduce recurrence.

Results: At 9 months of follow-up of the patient, there was significant improvement in signs and symptoms with no signs of recurrence.

Conclusion: This case highlights the rare co-existence of CG and PCG, emphasizing the need for a comprehensive diagnostic approach to exclude systemic causes. Successful management requires pharmacological treatment, surgical interventions, and dietary modifications. Long-term follow-up is essential to monitor recurrences and maintain clinical stability.

Key points: Because of the rare co-occurrence of cheilitis granulomatosis (CG) and plasma cell gingivitis (PCG), which creates unique diagnostic and therapeutic hurdles, this case offers new information. Additionally, it presents an effective treatment plan that concurrently addresses both problems. A comprehensive strategy is necessary for the successful management of PCG and CG. Systemic disorders must be ruled out since they might exhibit similar symptoms. Dietary changes, nonsurgical, and surgical periodontal therapy are all part of the therapy plan. In order to avoid recurrence and guarantee a long-lasting recovery, long-term monitoring and regular elimination of allergens and irritants are essential. The possibility of the problem recurring is one of the main obstacles to this case's success. Reducing the chance of recurrence requires adhering to dietary changes and getting rid of allergens. Additionally, before initiating any kind of treatment, systemic disorders must be ruled out.

Plain language summary: Cheilitis granulomatosa (CG) and plasma cell gingivitis (PCG) are two uncommon conditions that affect the oral cavity. In this case report, a 32-year-old female patient presented with swelling of the lip and enlargement of the gums. There was a presence of cracks at the corners of the mouth, along with redness of gums with uneven texture. Investigations were done to rule out other possible causes of the same. His

背景:口腔溃疡性肉芽肿(CG)和浆细胞性牙龈炎(PCG)是影响口腔区域的罕见炎症。CG表现为慢性嘴唇肿胀伴肉芽肿性炎症,而PCG表现为与过敏反应相关的牙龈红斑或牙龈肿大。它们同时发生的情况极为罕见,这给诊断和治疗带来了挑战。方法:一名32岁女性,以复发性上唇肿胀和牙龈肿大为主。临床检查发现牙龈炎,牙质呈鹅卵石状,牙龈炎呈角状。活检证实口面部肉芽肿伴上皮样肉芽肿,PCG伴浆细胞浸润。治疗包括饮食调整和牙周干预。术后结果有显著改善,并实施了消除过敏原的策略以减少复发。结果:随访9个月,患者体征和症状明显改善,无复发迹象。结论:本病例突出了CG和PCG的罕见共存,强调需要全面的诊断方法来排除全身性原因。成功的治疗需要药物治疗、手术干预和饮食调整。长期随访对监测复发和维持临床稳定性至关重要。由于阴唇炎、肉芽肿病(CG)和浆细胞性牙龈炎(PCG)的罕见共存,造成了独特的诊断和治疗障碍,本病例提供了新的信息。此外,它提出了一个有效的治疗计划,同时解决这两个问题。一个全面的战略是成功管理PCG和CG的必要条件。必须排除全身性疾病,因为它们可能表现出类似的症状。饮食改变,非手术和手术牙周治疗都是治疗计划的一部分。为了避免复发和保证持久的恢复,长期监测和定期消除过敏原和刺激物是必不可少的。问题再次出现的可能性是本案成功的主要障碍之一。减少复发的机会需要坚持饮食改变和摆脱过敏原。此外,在开始任何治疗之前,必须排除全身性疾病。摘要:口腔溃疡性肉芽肿(CG)和浆细胞性牙龈炎(PCG)是影响口腔的两种罕见疾病。在这个病例报告中,一位32岁的女性患者表现为嘴唇肿胀和牙龈肿大。嘴角有裂缝,牙龈发红,质地不均匀。进行了调查以排除其他可能的原因。唇和牙龈的组织病理学分析证实了CG和PCG的诊断。患者接受了非手术和手术牙周治疗,并接受了避免饮食中可能存在的过敏原的教育。治疗后症状缓解。患者随访9个月,无复发迹象。
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引用次数: 0
Cone beam computed tomography of bone dimensions in periodontally accelerated osteogenic orthodontics: A retrospective study. 牙周加速成骨正畸中骨尺寸的锥形束计算机断层扫描:一项回顾性研究。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-17 DOI: 10.1002/cap.10351
Trevor D Richmond, Ayman Al Dayeh, Mark Scarbecz, Sidney Stein, Jack Fisher, Vrushali Abhyankar

Background: Periodontally accelerated osteogenic orthodontics (PAOO) or surgically facilitated orthodontics involves corticotomies and bone grafts during orthodontic treatment. It aims to enhance the range and rate of tooth movement and improve alveolar bone dimension and gingival architecture. Limited evidence exists on bone dimension changes due to PAOO. This retrospective study assesses PAOO's effects on alveolar bone thickness.

Methods: Patient records from 15 arches treated with PAOO were compared to 15 age and sex-matched control arches treated without PAOO. Pre- and post-orthodontic cone-beam computed tomography images measured radicular bone thickness at central and lateral incisors in sagittal sections at 3, 6, 9, and 12 mm from the cemento-enamel junction (CEJ). The vertical distance of crestal bone from CEJ was also measured. Fenestrations or dehiscence were quantified on buccal root surface cross-sections.

Results: Of the 15 PAOO-treated arches, 10 were augmented on the compression side of tooth movement, while five were augmented on the tension side. In cases augmented on the compression side, the PAOO group showed a significant increase in the buccal radicular bone at 3, 6, and 9 mm from the CEJ. A significant loss in lingual crestal bone height was observed in the PAOO group. Additionally, there was a significant reduction in fenestrations and dehiscence in the PAOO group.

Conclusions: Within our study's limitations, results suggest that PAOO increases alveolar bone thickness and reduces fenestration and dehiscence incidence when performed on the compression side of orthodontic movement. However, it is associated with lingual crestal bone loss. Further prospective studies with standardized protocols are needed to better define PAOO's efficacy.

Key points: Periodontally accelerated osteogenic orthodontics (PAOO) increases the thickness of alveolar bone when performed on the compression side of the orthodontic tooth movement. PAOO may prevent alveolar fenestrations and dehiscence of root surfaces after orthodontic treatment. PAOO may reduce orthodontic treatment time in select cases.

Plain language summary: With an improved awareness of dental esthetics and function, an increased number of adult individuals are seeking orthodontic therapy. Adult patients present with unique challenges for the treating orthodontist such as extensive restorative work, missing teeth, thin alveolar bone, and thin gingival tissues. This might result in increased recession, bone loss and fenestration, and dehiscence. Periodontally accelerated osteogenic orthodontics (PAOO) allows for quicker tooth movement, as well as increasing alveolar bone thickness to prevent subsequent hard and soft tissue deficiencies. In this retrospective study, we compared the effects of orthodontic treatment completed with and without PAOO on alve

背景:牙周加速成骨正畸(PAOO)或手术辅助正畸包括正畸治疗期间的皮质切开术和骨移植。它旨在提高牙齿运动的范围和速度,改善牙槽骨尺寸和牙龈结构。关于PAOO引起的骨尺寸变化的证据有限。本回顾性研究评估PAOO对牙槽骨厚度的影响。方法:将15例经PAOO治疗的足弓患者记录与15例年龄和性别匹配的未经PAOO治疗的对照足弓进行比较。正畸前和正畸后锥形束计算机断层图像测量了中切牙和侧切牙矢状面距离牙髓-牙釉质交界处(CEJ) 3,6,9,12 mm处的根状骨厚度。同时测量了冠骨与CEJ的垂直距离。在颊根表面横截面上定量观察开孔或开裂情况。结果:15个经paoo处理的牙弓中,有10个在牙齿运动的受压侧增强,5个在拉伸侧增强。在受压侧增强的病例中,PAOO组在距CEJ 3,6和9mm处的颊根骨显著增加。PAOO组舌嵴骨高度明显下降。此外,PAOO组的开窗率和裂开率显著降低。结论:在我们研究的局限性内,结果表明,在正畸运动受压侧进行PAOO可增加牙槽骨厚度,减少开窗和开裂的发生率。然而,它与舌嵴骨质流失有关。需要采用标准化方案的进一步前瞻性研究来更好地确定PAOO的疗效。重点:牙周加速成骨正畸(PAOO)在正畸牙齿移动的受压侧进行时,会增加牙槽骨的厚度。PAOO可以防止正畸治疗后的牙槽开孔和牙根表面开裂。在某些情况下,PAOO可以缩短正畸治疗时间。摘要:随着对牙齿美学和功能意识的提高,越来越多的成年人正在寻求正畸治疗。成年患者对治疗正畸医生提出了独特的挑战,如广泛的修复工作,缺牙,薄的牙槽骨和薄的牙龈组织。这可能会导致骨质萎缩、骨质流失和骨质疏松。牙周加速成骨正畸(PAOO)允许更快的牙齿运动,以及增加牙槽骨厚度,以防止随后的硬组织和软组织缺陷。在这项回顾性研究中,我们比较了有和没有PAOO的正畸治疗对牙槽骨厚度的影响。我们的研究结果表明,PAOO组骨厚度增加,开窗和开裂的发生率降低。PAOO组颊侧牙冠骨高度保持不变,但腭侧牙根垂直骨明显减少。PAOO组有更多的牙齿运动和治疗时间缩短的趋势。需要进一步的研究来减少样本不一致性和标准化PAOO技术。
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引用次数: 0
Intentional replantation of periodontally compromised teeth with concentrated growth factors. 用浓缩生长因子对牙周受损牙齿进行再植。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-14 DOI: 10.1002/cap.70017
Nabeel Ayappali Kalluvalappil, R Saravana Kumar, Tamer Hamed Hassan
<p><strong>Background: </strong>Intentional replantation (IR) has been described as a potential treatment modality for periodontally compromised anterior teeth deemed hopeless, particularly when combined with regenerative biomaterials such as concentrated growth factor (CGF). However, high-level evidence documenting cone-beam computed tomography (CBCT)-based outcomes in such cases remains limited. This paper evaluates the clinical and radiographic outcomes of IR using CGF in anterior teeth with advanced periodontal bone loss over a 1-year follow-up period.</p><p><strong>Methods: </strong>Ten patients with single-rooted anterior teeth exhibiting advanced periodontal disease underwent atraumatic extraction, extraoral debridement, CGF application to both socket and root surface, and immediate replantation followed by semi-rigid splinting for 4 weeks. Clinical parameters (probing depth [PD], mobility, and gingival index), patient-centered outcomes (pain scores and oral health-related quality of life), and CBCT imaging were assessed at baseline and 12 months postoperatively.</p><p><strong>Results: </strong>All cases showed favorable clinical healing, with significant reductions in mobility and PD. CBCT analysis revealed a mean gain in alveolar bone height of 2.58  ±  0.43 mm from baseline to 12 months. Pain was reduced significantly (mean pain scores (Visual Analog Scale) changed from 6.1 ± 0.7 to 0.6 ± 0.5). Oral Health Impact Profile-14 (OHIP-14) scores improved from 18.9 ± 1.32 to 4.6 ± 0.54. No cases of root resorption or ankylosis were observed.</p><p><strong>Conclusion: </strong>Within the limitations of this case study without controls, IR using CGF was associated with clinically stable outcomes and radiographic evidence of bone fill at 1 year in these selected cases. This approach may be considered a potential alternative to extraction in specific clinical scenarios.</p><p><strong>Trial registration: </strong>NCT06893107; US National Institutes of Health Clinical Trials Registry KEY POINTS: Intentional replantation (deliberate removal of teeth, extraoral treatment, and reinsertion into the same socket) can be considered a conservative approach to preserve anterior teeth with severe periodontal compromise. The addition of concentrated growth factor during this clinical approach resulted in clinical stability and radiographic bone fill at 12 months. Controlled long-term studies are needed before clinical adoption, as the findings from the current small case series are descriptive.</p><p><strong>Plain language summary: </strong>Sometimes, badly damaged front teeth are removed because they seem beyond saving. But what if we could carefully take them out, clean them, add natural healing material, and put them back? In this study, 10 patients with severely loose front teeth due to gum disease had their teeth gently extracted and treated with a substance made from their blood called concentrated growth factor (CGF). The teeth were cleaned, coated wit
背景:有意再植(IR)被认为是治疗牙周受损无望的前牙的一种潜在治疗方式,特别是当与再生生物材料(如浓缩生长因子(CGF))结合使用时。然而,在此类病例中,基于锥束计算机断层扫描(CBCT)结果的高水平证据仍然有限。本文通过1年的随访,评估了使用CGF治疗晚期牙周骨质流失的前牙的临床和影像学结果。方法:对10例牙周病晚期的单根前牙进行无伤性拔牙、口外清创、牙槽及牙根表面应用CGF、即刻再植、半刚性夹板固定4周。临床参数(探探深度[PD]、活动度和牙龈指数)、以患者为中心的结果(疼痛评分和口腔健康相关生活质量)以及CBCT成像在基线和术后12个月进行评估。结果:所有病例均表现出良好的临床愈合,活动能力和PD显著降低。CBCT分析显示,从基线到12个月,牙槽骨高度平均增加2.58±0.43 mm。疼痛明显减轻(平均疼痛评分(视觉模拟量表)从6.1±0.7变为0.6±0.5)。口腔健康影响量表-14 (OHIP-14)评分由18.9±1.32分提高至4.6±0.54分。无牙根吸收或强直病例。结论:在这个没有对照的病例研究的局限性内,在这些选定的病例中,使用CGF的IR与临床稳定的结果和1年后骨填充的影像学证据相关。在特定的临床情况下,这种方法可能被认为是一种潜在的替代拔牙的方法。试验注册:NCT06893107;美国国立卫生研究院临床试验注册中心要点:故意再植(故意拔除牙齿,口外治疗,并重新插入同一牙槽)可以被认为是一种保守的方法来保护牙周严重受损的前牙。在这种临床方法中添加浓缩生长因子导致临床稳定性和12个月时的x线骨填充。在临床采用之前,需要进行对照长期研究,因为目前小病例系列的研究结果是描述性的。简单的语言总结:有时,严重损坏的门牙被拔掉,因为它们似乎无法挽救。但如果我们能小心翼翼地把它们拿出来,清洗干净,添加天然修复材料,然后再放回去呢?在这项研究中,10名因牙龈疾病导致门牙严重松动的患者将他们的牙齿轻轻地拔出来,并用一种由他们的血液制成的物质进行治疗,这种物质被称为浓缩生长因子(CGF)。清洁牙齿,涂上CGF,并立即重新种植。一年后,这些牙齿不仅稳定,疼痛减轻,而且x光显示它们周围长出了新的骨头。牙齿周围平均形成的新骨约为2.6毫米,这是愈合的强烈迹象。与手术前相比,患者报告的疼痛减轻了很多,生活质量也提高了。重要的是,没有一颗牙齿显示出与骨头融合或断裂的迹象。这种方法被称为CGF的有意再植(IR),它可以给原本会丢失的牙齿提供第二次机会,并且在某些情况下可以减少对种植体的需求。
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引用次数: 0
Patient satisfaction among periodontally stable patients with veneer restorations-A retrospective study. 牙周稳定的贴面修复患者满意度的回顾性研究。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-14 DOI: 10.1002/cap.70020
Amelie M Bäumer, Christoper T Riemer, Christopher Büsch, Gerd A Körner, Johanna A Gaß
<p><strong>Background: </strong>Successful periodontal therapy may yield poor esthetic outcomes, impacting patient satisfaction, and while adhesive ceramic veneers demonstrate success in esthetically compromised cases, their effectiveness in periodontally compromised patients' satisfaction remains unexplored. Therefore, this retrospective study assesses patient-reported quality of life and satisfaction in periodontally healthy and stable patients with anterior ceramic veneer restorations.</p><p><strong>Methods: </strong>Patients, both periodontally healthy and stable, who received anterior veneer restorations at least 5 years ago, participated in the study. Satisfaction data, Oral Health Impact Profile (OHIP-G14), and Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ) scores were collected, and groups were categorized based on periodontal diagnosis (healthy, stage I/II, stage III/IV). Veneers were evaluated using pink esthetic score (PES) and white esthetic score (WES) criteria.</p><p><strong>Results: </strong>Analysis of 68 patients and 312 veneers with an average 8-year follow-up revealed high satisfaction with anterior veneer restorations. The study indicates that veneers positively impact oral health-related quality of life (OHRQoL) for patients with and without severe attachment loss, with mild periodontitis potentially enhancing satisfaction. The PES score is lower in patients with severe periodontitis (mean ± SD: 7.33 ± 1.78, p < 0.01).</p><p><strong>Conclusion: </strong>The results emphasize the positive impact on functionality and esthetic quality, suggesting that veneer restorations in the anterior region are a beneficial treatment option for improving OHRQoL, independent from attachment loss due to periodontitis.</p><p><strong>Key points: </strong>Veneer restorations significantly improve patient satisfaction and oral health-related quality of life (OHRQoL), even in patients with a history of periodontitis. This suggests veneers are a viable esthetic solution regardless of previous periodontal attachment loss. While patients with severe periodontitis may exhibit lower pink esthetic scores (PES), the white esthetic outcome (WES) and overall patient satisfaction remain high. This underlines the importance of managing expectations regarding soft tissue esthetics without compromising the perceived success of the treatment. Anterior ceramic veneers should be considered a reliable treatment option for esthetic rehabilitation in both periodontally healthy and previously compromised patients, when periodontal stability is achieved.</p><p><strong>Plain language summary: </strong>Periodontal disease can compromise both the function and appearance of anterior teeth, and even after successful treatment, patients may remain dissatisfied with esthetic outcomes. This study evaluated whether anterior ceramic veneers could improve patient-reported outcomes, particularly oral health-related quality of life (OHRQoL), in individuals with varyi
背景:成功的牙周治疗可能会产生不良的美学结果,影响患者的满意度,虽然粘接陶瓷贴面在美学受损的情况下取得了成功,但其在牙周受损患者满意度方面的有效性仍未得到探索。因此,本回顾性研究评估患者报告的牙周健康和稳定的前牙瓷贴面修复患者的生活质量和满意度。方法:研究对象为牙周健康稳定且至少5年前接受过前牙贴面修复的患者。收集满意度数据、口腔健康影响量表(OHIP-G14)和口腔美学心理社会影响问卷(PIDAQ)得分,并根据牙周诊断(健康、I/II期、III/IV期)进行分组。采用粉红色美学评分(PES)和白色美学评分(WES)标准对贴面进行评价。结果:对68例患者和312个烤瓷牙进行了平均8年的随访,结果显示烤瓷牙对烤瓷牙前牙体修复的满意度较高。该研究表明,贴面对有或没有严重附着丧失的患者的口腔健康相关生活质量(OHRQoL)有积极影响,轻度牙周炎可能会提高满意度。重度牙周炎患者PES评分较低(平均±SD: 7.33±1.78,p < 0.01)。结论:结果强调了对功能和美学质量的积极影响,表明前牙区贴面修复是改善OHRQoL的有益治疗选择,与牙周炎引起的附着丧失无关。重点:即使是有牙周炎病史的患者,贴面修复也能显著提高患者满意度和口腔健康相关生活质量(OHRQoL)。这表明贴面是一个可行的美观的解决方案,无论以前的牙周附着丧失。虽然严重牙周炎患者可能表现出较低的粉红色美学评分(PES),但白色美学结果(WES)和总体患者满意度仍然很高。这强调了在不影响治疗成功的前提下管理软组织美学期望的重要性。当牙周稳定后,对于牙周健康和先前受损的患者来说,前牙贴面应该被认为是一种可靠的美学康复治疗选择。简单的语言总结:牙周病会损害前牙的功能和外观,即使治疗成功,患者仍可能对美观结果不满意。本研究评估了在不同牙周健康程度的个体中,前牙陶瓷贴面是否可以改善患者报告的结果,特别是口腔健康相关生活质量(OHRQoL)。68例患者,包括牙周健康和病情稳定的I-IV期牙周炎患者,在接受前牙贴面治疗至少5年后进行回顾性评估。通过有效的问卷调查和临床美学评分,研究发现所有组的患者满意度都保持在较高水平。值得注意的是,轻度牙周炎患者的满意度最高,即使是晚期附着丧失患者的OHRQoL也有所改善。重度牙周炎患者的粉红色审美评分(PES)较低,而白色审美评分(WES)组间差异无统计学意义。这些研究结果表明,无论牙周病史如何,前牙陶瓷贴面是一种可靠有效的修复选择,可以提高美学和社会心理结果,并可能在既往牙周病患者的综合康复护理中发挥重要作用。
{"title":"Patient satisfaction among periodontally stable patients with veneer restorations-A retrospective study.","authors":"Amelie M Bäumer, Christoper T Riemer, Christopher Büsch, Gerd A Körner, Johanna A Gaß","doi":"10.1002/cap.70020","DOIUrl":"https://doi.org/10.1002/cap.70020","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Successful periodontal therapy may yield poor esthetic outcomes, impacting patient satisfaction, and while adhesive ceramic veneers demonstrate success in esthetically compromised cases, their effectiveness in periodontally compromised patients' satisfaction remains unexplored. Therefore, this retrospective study assesses patient-reported quality of life and satisfaction in periodontally healthy and stable patients with anterior ceramic veneer restorations.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Patients, both periodontally healthy and stable, who received anterior veneer restorations at least 5 years ago, participated in the study. Satisfaction data, Oral Health Impact Profile (OHIP-G14), and Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ) scores were collected, and groups were categorized based on periodontal diagnosis (healthy, stage I/II, stage III/IV). Veneers were evaluated using pink esthetic score (PES) and white esthetic score (WES) criteria.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Analysis of 68 patients and 312 veneers with an average 8-year follow-up revealed high satisfaction with anterior veneer restorations. The study indicates that veneers positively impact oral health-related quality of life (OHRQoL) for patients with and without severe attachment loss, with mild periodontitis potentially enhancing satisfaction. The PES score is lower in patients with severe periodontitis (mean ± SD: 7.33 ± 1.78, p &lt; 0.01).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The results emphasize the positive impact on functionality and esthetic quality, suggesting that veneer restorations in the anterior region are a beneficial treatment option for improving OHRQoL, independent from attachment loss due to periodontitis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Key points: &lt;/strong&gt;Veneer restorations significantly improve patient satisfaction and oral health-related quality of life (OHRQoL), even in patients with a history of periodontitis. This suggests veneers are a viable esthetic solution regardless of previous periodontal attachment loss. While patients with severe periodontitis may exhibit lower pink esthetic scores (PES), the white esthetic outcome (WES) and overall patient satisfaction remain high. This underlines the importance of managing expectations regarding soft tissue esthetics without compromising the perceived success of the treatment. Anterior ceramic veneers should be considered a reliable treatment option for esthetic rehabilitation in both periodontally healthy and previously compromised patients, when periodontal stability is achieved.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Plain language summary: &lt;/strong&gt;Periodontal disease can compromise both the function and appearance of anterior teeth, and even after successful treatment, patients may remain dissatisfied with esthetic outcomes. This study evaluated whether anterior ceramic veneers could improve patient-reported outcomes, particularly oral health-related quality of life (OHRQoL), in individuals with varyi","PeriodicalId":55950,"journal":{"name":"Clinical Advances in Periodontics","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145287852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel overlapping rotated double flap: A modified pedicle technique for root coverage in isolated RT1 gingival recession-Case study of two patients. 新型重叠旋转双瓣:一种改良的根蒂技术用于孤立RT1牙龈退缩的根覆盖-两例病例研究。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-14 DOI: 10.1002/cap.70018
Ritika Arora, Sakshi Verma, Ridhima Singhal, Nitika Monga, Rajinder K Sharma, Shikha Tewari
<p><strong>Background: </strong>This case report presents a modified pedicle flap technique-the novel overlapping rotated double (NORD) flap-as an alternative to conventional approaches such as coronally advanced flap with subepithelial connective tissue graft (SCTG). While SCTG offers predictable outcomes, it involves a second surgical site, increasing patient morbidity. In contrast, the NORD flap uses adjacent pedicle flaps in an overlapping design, with one flap mimicking a connective tissue graft, thereby enhancing tissue thickness and vascularity without donor site complications.</p><p><strong>Methods: </strong>Two systemically healthy patients-a 35-year-old female with a thick gingival phenotype and a 40-year-old male with a thin phenotype-presenting with isolated recession type 1 (RT1) gingival recessions were treated using the NORD flap. All procedures were performed under local anesthesia with standard postoperative protocols. Follow-ups were conducted at 14 days, 1 month, 6 months, and 12 months. Clinical outcomes were assessed using the root coverage esthetic score and patient-reported outcome measures.</p><p><strong>Results: </strong>Over 90% root coverage was achieved in both cases, regardless of phenotype. The technique eliminated graft harvesting, minimized complications, and was associated with minimal postoperative pain, requiring only two analgesic doses in 48 h.</p><p><strong>Conclusion: </strong>The NORD flap offers a conservative and effective alternative for managing isolated gingival recessions.</p><p><strong>Plain language summary: </strong>This case report introduces the novel overlapping rotated double (NORD) flap, a modified pedicle-based approach designed to overcome limitations associated with conventional root coverage procedures. Although the subepithelial connective tissue graft is considered the gold standard due to its predictability, the technique necessitates harvesting from a secondary donor site, thereby increasing patient morbidity and postoperative discomfort. The NORD flap provides a biologically driven alternative by utilizing two adjacent pedicle flaps in an overlapping configuration, one of which functions analogously to a connective tissue graft. This design enhances gingival thickness, vascularization, and stability of the flap while obviating the need for graft procurement. Two cases presenting with isolated RT1 recessions were managed using this approach. All surgeries were performed under local anesthesia, followed by routine postoperative care, and evaluated. Clinical parameters, including the root coverage esthetic score, and patient-reported outcome measures demonstrated favorable results, with >90% root coverage achieved in both cases. The technique was associated with minimal pain, rapid healing, and elimination of donor site morbidity, underscoring its potential as a conservative and effective alternative for isolated recession defects.</p><p><strong>Key points: </strong>Value of innovation:
背景:本病例报告提出了一种改良的蒂瓣技术-新型重叠旋转双瓣(NORD) -作为传统方法的替代方法,如冠状晚期皮瓣与上皮下结缔组织移植(SCTG)。虽然SCTG提供可预测的结果,但它涉及到第二个手术部位,增加了患者的发病率。相比之下,NORD瓣采用相邻蒂瓣重叠设计,其中一个瓣模仿结缔组织移植物,从而增加组织厚度和血管,没有供区并发症。方法:对2例全身健康的1型(RT1)牙龈萎缩患者(35岁,女性,厚型)和40岁,男性,薄型)应用NORD皮瓣进行治疗。所有手术均在局部麻醉下按照标准的术后方案进行。随访时间分别为14天、1个月、6个月、12个月。临床结果评估采用牙根覆盖美学评分和患者报告的结果测量。结果:在两种情况下,无论表型如何,根覆盖率均超过90%。该技术消除了移植,减少了并发症,术后疼痛最小,仅需48小时两次镇痛剂量。结论:NORD皮瓣为治疗孤立性牙龈衰退提供了一种保守而有效的替代方法。简单的语言总结:本病例报告介绍了一种新型的重叠旋转双瓣(NORD),一种改良的基于蒂的方法,旨在克服传统根覆盖手术的局限性。虽然上皮下结缔组织移植物因其可预测性而被认为是金标准,但该技术需要从二次供体部位采集,从而增加了患者的发病率和术后不适。NORD皮瓣提供了一种生物驱动的替代方案,利用两个相邻的蒂皮瓣重叠配置,其中一个功能类似于结缔组织移植物。这种设计增加了牙龈的厚度,血管化和皮瓣的稳定性,同时避免了移植的需要。采用这种方法处理了两个孤立的RT1衰退病例。所有手术均在局麻下进行,术后进行常规护理,并进行评估。临床参数,包括牙根覆盖美学评分和患者报告的结果测量显示出良好的结果,两种情况下均实现了90%的牙根覆盖。该技术具有疼痛最小、愈合迅速和消除供体部位发病率的特点,强调了其作为孤立性退行性缺损的保守和有效替代方法的潜力。关键点:创新价值:这种新颖的基于蒂的技术可以作为移植物收获的可行替代方案,在最小化患者发病率是优先考虑的情况下,从而避免了二次手术部位,或者当上皮下结缔组织移植物是禁忌或不需要的时候:在不同的牙龈表型中实现高根覆盖率(>90%),展示了多功能性。通过重叠蒂设计,模拟结缔组织移植物,增强软组织厚度和血管。减少术后不适,镇痛需求低。
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引用次数: 0
The connective tissue cube for treatment of papillary deficiencies: A case report. 结缔组织立方体治疗乳头状缺陷1例报告。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-14 DOI: 10.1002/cap.10371
Giuseppe Carvelli, Elli Anna Kotsailidi, Alexandra Tsigarida, Shalom Benzaquen, Konstantinos Chochlidakis, Carlo Ercoli, Jack G Caton

Background: Prevention and treatment of interproximal recessions after periodontal therapy has been challenging and is important because the resulting black triangles are unesthetic. Traditional treatment options include orthodontic, restorative, surgical, and combined approaches. This case report aims to describe an approach using periodontal plastic surgery combined with prosthetic treatment for the management of a papillary deficiency in the esthetic zone.

Methods: A healthy, 64-year-old female presented with esthetic concerns related to a black triangle between the maxillary right canine and first premolar as a result of periodontal therapy. A Class III recession defect was present. A de-epithelialized connective tissue graft harvested from the maxillary tuberosity was placed interproximally and combined with a coronally advanced flap and enamel matrix derivative. Following 6 months, the restorative phase was initiated including diagnostic wax-up, direct composite restoration the mesial of the premolar, followed by facial veneer preparation on the canine using an incisal butt joint design. After the provisional phase, a lithium disilicate ceramic veneer was fabricated and cemented with adhesive technique.

Results: Following 18 months of follow-up, we observed a nearly complete closure of the embrasure space.

Conclusions: The successful closure of the interproximal tissue deficiency, as evidenced by this case report, demonstrates the potential of this approach utilizing an interproximal connective tissue graft along with prosthetic treatment to manage significant papillary defects; this report reinforces the role combined prosthodontic and periodontic approaches may have in treatment outcomes.

Key points: The connective tissue cube technique showed potential for treatment of severe papillary deficiencies. Combined surgical-restorative approaches might be needed for complete closure of black triangles. Further clinical studies with stronger level of evidence are needed.

Plain language summary: This case report discusses a treatment for a common issue after periodontal therapy: black triangles (open gingival embrasures) between teeth that can be unappealing. The patient, a 64-year-old woman, had a black triangle between her maxillary right canine and first premolar due to loss of interproximal periodontal support. The treatment combined surgery (tissue and bone grafting with biologic material) and restorative treatment. After 6 months, dental restorations were complete, with a provisional period prior to definitive restoration to evaluate tissue fill and esthetics. The restorative treatment involved the use of a single veneer and single interproximal composite restoration. Eighteen months postsurgical therapy, the gap was nearly closed and remained stable for an additional 6 months. The report highlights that com

背景:牙周治疗后近端间衰退的预防和治疗一直是具有挑战性的,因为由此产生的黑色三角形是不美观的。传统的治疗方法包括正畸、修复、手术和综合方法。本病例报告的目的是描述一种方法使用牙周整形手术结合假体治疗的管理乳头状缺陷在审美区。方法:一名健康的64岁女性,因牙周治疗导致上颌右犬齿和第一前磨牙之间出现黑色三角形而引起审美问题。存在III级衰退缺陷。从上颌结节取下去上皮结缔组织移植物近端放置,并与冠状进展皮瓣和牙釉质基质衍生物结合。6个月后,开始修复阶段,包括诊断蜡蜡,直接复合修复前磨牙内侧,然后在犬齿上使用切齿对接设计进行面部贴面准备。在临时阶段后,制备了二硅酸锂陶瓷贴面,并用胶粘剂技术粘合。结果:经过18个月的随访,我们观察到气囊空间几乎完全闭合。结论:成功闭合近端间组织缺损,正如本病例报告所证明的那样,证明了该方法利用近端间结缔组织移植物和假体治疗来治疗显著乳头状缺损的潜力;本报告强调了修复和牙周联合入路在治疗结果中的作用。结缔组织立方体技术显示了治疗严重乳头状缺陷的潜力。对于完全闭合的黑色三角形,可能需要手术与修复相结合的方法。需要有更有力证据的进一步临床研究。简单的语言总结:本病例报告讨论了牙周治疗后常见问题的治疗方法:牙齿之间的黑色三角形(开放的牙龈膜)可能不吸引人。患者,64岁女性,由于失去近端牙周支持,上颌右犬齿和第一前磨牙之间出现黑色三角形。治疗结合手术(生物材料组织和骨移植)和修复治疗。6个月后,牙齿修复完成,在最终修复之前有一段临时时间来评估组织填充和美观。修复治疗包括使用单一贴面和单一近端间复合修复。手术治疗18个月后,间隙几乎闭合,并在另外6个月保持稳定。该报告强调,结合牙龈手术和修复治疗可以有效地治疗显著乳头状缺陷。
{"title":"The connective tissue cube for treatment of papillary deficiencies: A case report.","authors":"Giuseppe Carvelli, Elli Anna Kotsailidi, Alexandra Tsigarida, Shalom Benzaquen, Konstantinos Chochlidakis, Carlo Ercoli, Jack G Caton","doi":"10.1002/cap.10371","DOIUrl":"https://doi.org/10.1002/cap.10371","url":null,"abstract":"<p><strong>Background: </strong>Prevention and treatment of interproximal recessions after periodontal therapy has been challenging and is important because the resulting black triangles are unesthetic. Traditional treatment options include orthodontic, restorative, surgical, and combined approaches. This case report aims to describe an approach using periodontal plastic surgery combined with prosthetic treatment for the management of a papillary deficiency in the esthetic zone.</p><p><strong>Methods: </strong>A healthy, 64-year-old female presented with esthetic concerns related to a black triangle between the maxillary right canine and first premolar as a result of periodontal therapy. A Class III recession defect was present. A de-epithelialized connective tissue graft harvested from the maxillary tuberosity was placed interproximally and combined with a coronally advanced flap and enamel matrix derivative. Following 6 months, the restorative phase was initiated including diagnostic wax-up, direct composite restoration the mesial of the premolar, followed by facial veneer preparation on the canine using an incisal butt joint design. After the provisional phase, a lithium disilicate ceramic veneer was fabricated and cemented with adhesive technique.</p><p><strong>Results: </strong>Following 18 months of follow-up, we observed a nearly complete closure of the embrasure space.</p><p><strong>Conclusions: </strong>The successful closure of the interproximal tissue deficiency, as evidenced by this case report, demonstrates the potential of this approach utilizing an interproximal connective tissue graft along with prosthetic treatment to manage significant papillary defects; this report reinforces the role combined prosthodontic and periodontic approaches may have in treatment outcomes.</p><p><strong>Key points: </strong>The connective tissue cube technique showed potential for treatment of severe papillary deficiencies. Combined surgical-restorative approaches might be needed for complete closure of black triangles. Further clinical studies with stronger level of evidence are needed.</p><p><strong>Plain language summary: </strong>This case report discusses a treatment for a common issue after periodontal therapy: black triangles (open gingival embrasures) between teeth that can be unappealing. The patient, a 64-year-old woman, had a black triangle between her maxillary right canine and first premolar due to loss of interproximal periodontal support. The treatment combined surgery (tissue and bone grafting with biologic material) and restorative treatment. After 6 months, dental restorations were complete, with a provisional period prior to definitive restoration to evaluate tissue fill and esthetics. The restorative treatment involved the use of a single veneer and single interproximal composite restoration. Eighteen months postsurgical therapy, the gap was nearly closed and remained stable for an additional 6 months. The report highlights that com","PeriodicalId":55950,"journal":{"name":"Clinical Advances in Periodontics","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145287862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Customized three-dimensional-printed titanium mesh for alveolar bone augmentation: Retrospective consecutive case series. 定制三维打印钛网用于牙槽骨增强:回顾性连续病例系列。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-10 DOI: 10.1002/cap.70015
Kaio Henrique Soares, Catherine King, Daniel Palkovics, Raul Perez, Marcia Mbadu, Wagner R Duarte, Karin C Schey, Poliana M Duarte

Background: This retrospective case series evaluated linear and volumetric bone changes in alveolar bone defects treated with guided bone regeneration (GBR) using a next-generation customized three-dimensional (3D)-printed titanium mesh.

Methods: Medical history, surgical details, and cone beam computed tomography (CBCT) data were collected from patients undergoing GBR with the customized 3D-printed titanium mesh. CBCT subtraction analysis was performed using 3D digital models, created via spatial registration and semi-automatic segmentation. Outcomes included complication rates, linear bone measurements, volumetric hard tissue gain, graft volume stability, and augmentation efficacy.

Results: Nine cases were included: five combined large defects, two vertical large defects, and two combined medium defects. Two cases showed no complications, while seven had mesh exposure. Two cases experienced complete early mesh exposure (22.2%), resulting in total graft loss and premature removal. The mean linear vertical bone gain at the defect's middle plane was 5.7 ± 2.3 mm for large defects, 2.7 ± 0.5 mm for medium defects, and 4.8 ± 2.4 mm for both. The overall volumetric gain was 0.49 ± 0.20 cm3, with graft volume stability at 87.9 ± 19.5% and augmentation efficacy of 0.037 ± 0.012 cm3/mm.

Conclusions: Customized 3D-printed titanium mesh is a feasible and effective option for augmenting defective edentulous ridges, providing predictable outcomes in linear and volumetric gains. Mesh exposure is the most common complication.

Key points: Novelty and Contribution of These Cases This case series provides important insights into GBR using customized 3D-printed titanium meshes. These devices aim to overcome several limitations commonly associated with traditional non-resorbable membranes and conventional titanium meshes. The inclusion of comprehensive, CBCT-based linear and volumetric measurements of hard tissue gain adds valuable quantitative data to the field, supporting the clinical utility of customized titanium meshes in alveolar ridge augmentation. Key Factors for Successful Case Management Successful outcomes in these cases were associated with several critical factors: Thorough preoperative planning Precise execution of the surgical technique Effective management of potential postoperative mesh exposure Primary Limitations to Treatment Success The main limitations that impacted treatment outcomes included: Compromised systemic health or medical history Improper adaptation or seating of the mesh Premature and complete mesh exposure during the healing period PLAIN LANGUAGE SUMMARY: This study looked at a new way to rebuild lost bone in the jaw using a custom-made, three-dimensional (3D)-printed titanium mesh. Nine patients with different types of bone defects were treated, and detailed scans were taken before and after surger

背景:本回顾性病例系列评估了使用下一代定制三维(3D)打印钛网引导骨再生(GBR)治疗牙槽骨缺损时骨的线性和体积变化。方法:使用定制的3d打印钛网收集GBR患者的病史、手术细节和锥束计算机断层扫描(CBCT)数据。CBCT减法分析使用三维数字模型,通过空间配准和半自动分割创建。结果包括并发症发生率、线性骨测量、硬组织体积增加、移植物体积稳定性和增强效果。结果:9例:合并大缺陷5例,垂直大缺陷2例,合并中等缺陷2例。2例无并发症,7例有补片暴露。2例(22.2%)早期网状物完全暴露,导致移植物全部丢失和过早切除。大缺损的平均垂直骨增益为5.7±2.3 mm,中等缺损为2.7±0.5 mm,两者均为4.8±2.4 mm。总体体积增益为0.49±0.20 cm3,移植物体积稳定性为87.9±19.5%,增强效能为0.037±0.012 cm3/mm。结论:定制的3d打印钛网是增加有缺陷的无牙嵴的可行和有效的选择,在线性和体积增益方面提供可预测的结果。补片暴露是最常见的并发症。本案例系列提供了使用定制3d打印钛网的GBR的重要见解。这些装置旨在克服传统不可吸收膜和传统钛网的几个限制。包括全面的,基于cbct的硬组织增益的线性和体积测量,为该领域增加了有价值的定量数据,支持定制钛网在牙槽嵴增强中的临床应用。成功病例管理的关键因素这些病例的成功结果与几个关键因素有关:周密的术前计划精确的手术技术执行有效的术后潜在补片暴露管理治疗成功的主要限制影响治疗结果的主要限制包括:全身健康或病史受损网片适配或放置不当在愈合期间过早和完全暴露网片摘要:本研究探讨了一种使用定制的三维(3D)打印钛网重建颌骨丢失骨的新方法。9名患有不同类型骨缺损的患者接受了治疗,并在手术前后进行了详细的扫描,以测量骨生长情况。大多数患者都有一定的改善,较大的缺损骨高平均增加约5mm。平均而言,骨体积增加了大约半立方厘米,大部分移植骨随着时间的推移保持稳定。然而,最常见的问题是网状物暴露,这在两个病例中导致移植物丢失。成功的结果取决于仔细的计划,精确的手术,以及处理任何随后发生的补片暴露。使治疗更加困难的因素包括患者的健康问题和难以正确安装补片。总的来说,这项工作表明,定制的3d打印钛网是一种很有前途的工具,用于重建颌骨缺失或受损患者的颌骨。这项研究的详细测量结果为外科医生提供了有用的信息,并支持使用这些补片实现可预测的骨再生。
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引用次数: 0
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Clinical Advances in Periodontics
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