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Non-surgical and guided-bone-regeneration surgical management of Type-3b dens invaginatus with an apico-marginal defect: A case report. 用非手术和引导骨再生手术治疗伴有边缘缺损的 3b 型凹陷:病例报告。
IF 0.7 Q3 Medicine Pub Date : 2024-03-15 DOI: 10.1002/cap.10283
Aaliya Rahman, Sharique Alam, Afaf Zia, R K Tiwari, S Mukhtar Un Nisar Andrabi, Maahin Mahmood

Background: Dens invaginatus (DI), an unusual developmental anomaly is a challenge for the operating dentist with regard to its diagnosis and treatment. This case report presents the successful management of a Type-3b DI in a permanent maxillary lateral incisor associated with a large radicular cyst and communicating apico-marginal defect (Von Arx type IIb).

Methods and results: A 19-year-old female patient reported pain and palatal swelling. During the clinical examination, tooth #12 exhibited tenderness to percussion, and presented a deep periodontal pocket depth (PPD) of 12 mm, along with grade I mobility. Radiographic examination revealed a large peri-radicular radiolucency with atypical tooth morphology. Cone beam computed tomography clarified the complicated root canal anatomy to be Type-3b DI associated with an apico-marginal defect. The case was managed successfully by non-surgical endodontic therapy followed by surgical intervention utilizing a guided bone regenerative (GBR) approach. Eighteen-month follow-up showed an asymptomatic and functional tooth with a significant reduction in pocket depth. The periapical radiographs showed continued healing of the osseous defect.

Conclusions: The successful healing outcome of a challenging case, characterized by a complex DI morphology, a large peri-radicular lesion, a through-and-through defect, and a combined endodontic-periodontal apico-marginal defect was achieved through accurate diagnosis, treatment planning, and execution using contemporary endodontic and periodontal treatment techniques. The application of GBR techniques during the surgical phase of treatment may have contributed to the improved regenerative healing outcome in this case, which was initially considered prognostically questionable.

Key points: Why is this case new information? Type-3b DI exhibits a complex root canal structure, each case displaying unique characteristics, necessitating a case-specific treatment plan. In this case report the Type-3b DI morphology was associated with a large peri-radicular, through and through defect and combined endodontic periodontal apico-marginal defect. The treatment approach involved incorporating guided bone regenerative (GBR) principles during the surgical phase. This case report contributes to the existing evidence on the diagnosis and successful management of Type-3b DI with a concurrent apico-marginal defect. What are the keys to successful management of this case? The successful management of a prognostically challenging case was achieved through a closely integrated multidisciplinary coordination between the endodontist and periodontist. Utilization of contemporary techniques and tools contributed to the successful management The use of three-dimensional radiological examination through cone beam computed tomography enabled a precise preoperative assessment, facilitating the formulation of a

背景:牙隐窝(Dens invaginatus,DI)是一种不常见的发育异常,在诊断和治疗方面对牙科医生来说是一个挑战。本病例报告成功治疗了上颌恒侧切牙3b型DI,该患者伴有巨大根状囊肿和沟通性根尖边缘缺损(Von Arx IIb型):一名 19 岁的女性患者报告疼痛和腭肿胀。在临床检查中,12 号牙叩诊时有触痛,牙周袋深度(PPD)为 12 毫米,活动度为 I 级。放射线检查显示,牙齿周围有一个大的放射斑,牙齿形态不典型。锥形束计算机断层扫描明确了复杂的根管解剖为 3b 型 DI,伴有根尖边缘缺损。该病例通过非手术根管治疗获得成功,随后利用引导骨再生(GBR)方法进行了手术干预。18 个月的随访结果显示,该患者的牙齿无任何症状,功能正常,牙槽窝深度明显减小。根尖周X光片显示骨缺损继续愈合:通过准确的诊断、治疗计划以及使用现代牙髓和牙周治疗技术,成功治愈了一个具有挑战性的病例,该病例的特点是复杂的DI形态、巨大的根周病变、贯穿性缺损以及牙髓-牙周根尖边缘联合缺损。在手术治疗阶段应用 GBR 技术可能有助于改善该病例的再生愈合结果,而该病例最初被认为在预后方面存在问题:为什么本病例是新信息?3b 型根管炎的根管结构复杂,每个病例都具有独特的特征,因此需要制定针对具体病例的治疗方案。在本病例报告中,3b型DI的形态与大的根管周、贯穿缺损和牙髓牙周根尖边缘联合缺损有关。治疗方法包括在手术阶段采用引导骨再生(GBR)原则。本病例报告为诊断和成功治疗并发根尖边缘缺损的 3b 型 DI 提供了现有证据。成功处理该病例的关键是什么?通过牙体牙髓科医生和牙周科医生之间紧密的多学科协作,成功处理了这一具有预后挑战性的病例。通过锥形束计算机断层扫描进行三维放射学检查,可以进行精确的术前评估,有助于制定治疗计划,同时处理 3b 型 DI 形态和相关的根周病变。在根尖周围手术中采用 GBR 技术可能有助于同时伴有根尖边缘缺损(Von Arx IIb 型)的贯通性根尖周围缺损的愈合。本病例成功的主要限制因素是什么?根管解剖结构复杂,与 3b 型 DI 形态有关 根尖周贯穿性缺损较大,同时伴有根尖边缘缺损。难以对患者进行每周和长期随访。
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引用次数: 0
Guided coronally advanced flap to treat gingival recession: Digital workflow and case report. 引导性冠状前移皮瓣治疗牙龈退缩:数字化工作流程和病例报告。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-03-10 DOI: 10.1002/cap.10282
Mauro Pedrine Santamaria, Amanda Rossato, Manuela Maria Viana Miguel, Ingrid Fernandes Mathias-Santamaria, Marcelo Pereira Nunes, Lucas Araújo Queiroz

Background: The inherently technique-sensitive nature of periodontal plastic procedures demands a significant level of skill and expertise. The incorporation of three-dimensional (3D) printing technologies emerges as a potential strategy to optimize and simplify surgical procedures. This case report describes the digital workflow and presents the clinical outcomes achieved using a guided coronally advanced flap for the treatment of a single gingival recession (GR).

Methods and results: A female patient with a gingival recession type 1 (RT1 B-) defect on the mandibular second left premolar underwent successful treatment using a guided coronally advanced flap (g-CAF) and de-epithelized connective tissue graft (CTG). The digital planning included intraoral scanning of the mandible and hard palate using an intraoral scanner, with resulting polygon format (PLY) files exported for virtual model creation. The CAF guide was meticulously designed to orient horizontal and vertical incisions at the papillae base adjacent to the GR defect. For the donor site, a guide was specifically created, positioning the graft area 2 mm apically to the premolars' gingival margins. The delineation of this area involved two horizontal and vertical incisions, meticulously based on the dimensions of the GR. The digitally designed guides were then 3D-printed using a surgical guide-specific resin, contributing to the precise execution of the innovative surgical approach. Complete root coverage was achieved.

Conclusion: This case report demonstrates that g-CAF can be a promising approach for the treatment of single GR.

Highlights: Why is this case new information? To the best of the authors' knowledge, this is the first manuscript to report a guided procedure for the treatment of gingival recession. This report provides the digital workflow for the fabrication of a guide to perform the coronally advanced flap for single recession defects. What are the keys to successfully manage this case? It is necessary to adequately scan the recession defect area and palate. Properly not only design the guide using specific software but also print it. The guide has to be stable when in position for the surgical procedure. What are the primary limitations of this technique? This guide was designed to help surgeons during the incisions. However, it does not provide aid to split and release the flap and suture.

背景:牙周整形手术本身对技术的敏感性要求高超的技能和专业知识。三维(3D)打印技术的应用成为优化和简化手术过程的潜在策略。本病例报告描述了数字化工作流程,并介绍了使用引导性冠状前进瓣治疗单个牙龈退缩(GR)所取得的临床效果:一名下颌第二左前磨牙1型(RT1 B-)牙龈退缩缺损的女性患者成功接受了引导下冠状先进皮瓣(g-CAF)和去上皮结缔组织移植(CTG)治疗。数字化规划包括使用口内扫描仪对下颌骨和硬腭进行口内扫描,然后导出多边形格式(PLY)文件用于创建虚拟模型。CAF 导板经过精心设计,以确定与 GR 缺损相邻的乳头基底部水平和垂直切口的方向。对于供体部位,还专门制作了一个导板,将移植区域定位在前磨牙龈缘根尖 2 毫米处。该区域的划定包括两个水平和垂直切口,均根据牙龈缺损的尺寸精心设计。然后,使用手术导板专用树脂对数字设计的导板进行 3D 打印,从而实现了创新手术方法的精确实施。最终实现了完全的牙根覆盖:本病例报告表明,g-CAF 是治疗单个 GR 的一种很有前景的方法:为什么本病例是新信息?据作者所知,这是第一份报告牙龈退缩治疗引导程序的手稿。本报告提供了制作引导器的数字化工作流程,用于对单发牙龈退缩缺损进行冠状前移翻瓣术。成功处理该病例的关键是什么?必须充分扫描退缩缺损区域和上腭。不仅要使用特定软件正确设计导板,还要正确打印导板。导板在手术过程中必须保持稳定。这种技术的主要局限性是什么?这种导板的设计目的是帮助外科医生进行切口。但是,它不能帮助分割和释放皮瓣和缝合线。
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引用次数: 0
Histologic wound healing in studies using different ridge preservation protocols: A review 采用不同脊柱保存方案的研究中的组织学伤口愈合:综述。
IF 0.7 Q3 Medicine Pub Date : 2024-03-07 DOI: 10.1002/cap.10281
Brian L. Mealey, Francis Keeling, A. Archontia Palaiologou

Background

Alveolar ridge preservation (ARP) procedures are designed to lessen dimensional changes in the alveolar ridge after tooth extraction. Wound healing after ridge preservation involves the formation of new vital bone in the former socket, and this vital bone is important in the osseointegration of dental implants.

Methods

A series of ARP studies have been performed to help clinicians better understand the wound-healing events that occur following tooth extraction and ridge preservation. Different protocols have been examined using various materials and periods of healing time prior to implant placement. The primary aim of these studies was to ascertain the relative percentage of vital bone formation, residual graft material, and connective tissue (CT)/other at the healing site using histomorphometric examination of bone core biopsies obtained during osteotomy preparation.

Results

For allografts, the use of demineralized bone alone or in combination with mineralized is associated with more vital bone formation than the use of mineralized allograft alone. For mineralized allografts, the use of cortical versus cancellous bone has only minimal impact on new bone formation. Xenografts from bovine and porcine sources appear to have similar vital bone formation. Longer healing times prior to implant placement are associated with increased vital bone formation and decreased residual graft material. The most stable component in most studies is the percentage of CT/other.

Conclusions

The percentage of vital bone and residual graft at ARP sites is dependent on the materials used and the length of healing time prior to obtaining core biopsies.

Key Points

What factors may affect the amount of new bone at the ARP site?
  1. At a time point about 4 months after ARP, the type of graft material used for ARP plays a large role in new bone formation.
  2. Studies focus on means and standard deviations, but patients often do not “follow the mean.” Even if a single ARP protocol is used for all patients, there is great interindividual variability in new bone formation, and there is often variability between sites within a single patient.
How long after ARP with an allograft should I wait
背景:牙槽嵴保留(ARP)手术旨在减轻拔牙后牙槽嵴的尺寸变化。牙槽嵴保留术后的伤口愈合涉及到前牙槽窝中新的重要骨质的形成,而这些重要骨质对于牙科种植体的骨结合非常重要:方法:为了帮助临床医生更好地了解拔牙和保留牙脊后的伤口愈合情况,我们进行了一系列 ARP 研究。在植入种植体之前,使用不同的材料和愈合时间对不同的方案进行了研究。这些研究的主要目的是通过对截骨准备过程中获得的骨核活检组织形态学检查,确定愈合部位的活力骨形成、残留移植材料和结缔组织(CT)/其他的相对比例:结果:对于同种异体移植物,与单独使用矿化同种异体移植物相比,单独使用或与矿化同种异体移植物一起使用脱矿化骨形成的活力骨更多。对于矿化同种异体移植物,使用皮质骨还是松质骨对新骨形成的影响微乎其微。来自牛和猪的异种移植物似乎具有相似的活力骨形成。种植体植入前较长的愈合时间与活力骨形成增加和移植材料残留减少有关。大多数研究中最稳定的成分是 CT/其他的百分比:结论:ARP部位的活力骨和残余移植物的百分比取决于所使用的材料和获得核心活检前愈合时间的长短:要点:哪些因素会影响ARP部位的新骨量?在 ARP 术后 4 个月左右的时间点,ARP 所用移植材料的类型对新骨形成有很大影响。研究的重点是平均值和标准偏差,但患者往往不会 "遵循平均值"。即使对所有患者使用单一的 ARP 方案,新骨形成的个体差异也很大,而且单个患者的不同部位之间往往也存在差异。使用同种异体骨进行 ARP 后,应该等待多长时间才能植入种植体?一般来说,较长的愈合时间(如 4-5 个月)比较短的愈合时间(如 2-3 个月)能形成更多的重要骨量。随着愈合时间的延长,不同 ARP 方案之间的活力骨形成差异往往会减小。含有脱矿物质骨的 FDBA,无论是单独使用还是与矿化 FDBA 结合使用,其新骨形成量通常高于 100% 矿化同种异体移植,尤其是在较短的愈合期。即使在使用同种异体骨进行 ARP 一年后,ARP部位仍会有残留的移植材料。
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引用次数: 0
Epithelial cyst following subepithelial connective tissue graft: A case report. 上皮下结缔组织移植后的上皮囊肿:病例报告。
IF 0.7 Q3 Medicine Pub Date : 2024-03-02 DOI: 10.1002/cap.10284
Julien de Paula, Luise A B da Silva, Mariane A S Wayar, Eduardo B Campagnoli, Fábio A Dos Santos

Background: Various surgical approaches have been employed to manage gingival recession, including subepithelial connective tissue grafting, which has yielded favorable outcomes.

Methods and results: We present the case of a 17-year-old patient who developed gingival recession on tooth #6 following an esthetic crown lengthening procedure. The recession was treated with a subepithelial connective tissue graft; however, this case details the occurrence of two epithelial cysts adjacent to the region subjected to the surgical procedure, 6 months after surgery. The treatment involved periodontal surgical intervention, during which the lesions were completely excised and the associated osseous defect was filled using an inorganic bovine bone matrix along with a collagen membrane. The healing progressed without any complications. Histopathological analysis revealed the presence of cystic lesions, which were characterized by a cystic cavity lined with stratified orthokeratinized epithelium with cuboidal cells in some areas surrounded by fibrous connective tissue. The patient's progress was monitored through tomography performed 6 months, 1 year, and 5 years post-procedure, all of which demonstrated the absence of any signs of lesion recurrence.

Conclusion: This case study emphasizes the effectiveness and predictability of subepithelial connective tissue grafting in the treatment of gingival recession. However, dental professionals should be cautious about the potential risk of gingival recession following esthetic crown lengthening procedures and recognize the potential complications associated with subepithelial connective tissue grafting, such as the observed development of epithelial cysts in this specific case.

Key points: Why is this case new information? We present a case of an epithelial cyst following a subepithelial connective tissue graft, which resulted in buccal cortical bone resorption. The treatment involved excisional biopsy and the use of an inorganic bovine bone matrix with a collagen membrane. What are the keys to the successful management of this case? Successful treatment included periodontal surgery, bone defect filling using an inorganic bovine bone matrix and a collagen membrane, and regular monitoring with CT scans at 6 months, 1 year, and 5 years post-surgery; all showed no recurrence. Success factors included careful surgery, appropriate biomaterial usage, and ongoing follow-up. What are the primary limitations to success in this case? The limitations involve potential complications from subepithelial connective tissue grafting such as cyst development. This report stresses the importance of meticulous patient selection and periodontal phenotype evaluation to minimize risks. Continuous follow-up is critical to detect recurrence and other issues.

背景:人们采用了多种手术方法来治疗牙龈退缩,包括上皮下结缔组织移植术,并取得了良好的效果:本病例是一名 17 岁的患者,在进行牙冠美容延长术后,6 号牙出现牙龈退缩。该病例采用上皮下结缔组织移植术治疗牙龈退缩,但在术后 6 个月,手术区域附近出现了两个上皮囊肿。治疗包括牙周手术干预,在手术过程中完全切除了病灶,并使用无机牛骨基质和胶原膜填充了相关的骨缺损。愈合进展顺利,未出现任何并发症。组织病理学分析表明存在囊性病变,其特征是囊腔内衬有分层的角化上皮,部分区域有立方体细胞,周围有纤维结缔组织。通过术后 6 个月、1 年和 5 年的断层扫描,对患者的病情进展进行了监测,结果显示没有任何病变复发的迹象:本病例研究强调了上皮下结缔组织移植治疗牙龈退缩的有效性和可预测性。然而,牙科专业人员应谨慎对待牙冠美容延长术后牙龈退缩的潜在风险,并认识到上皮下结缔组织移植术的潜在并发症,如在本病例中观察到的上皮囊肿的发生:为什么本病例是新信息?我们介绍了一例上皮下结缔组织移植后上皮囊肿的病例,该病例导致了口腔皮质骨吸收。治疗方法包括切除活检和使用带有胶原膜的无机牛骨基质。成功治疗该病例的关键是什么?成功的治疗包括牙周手术、使用无机牛骨基质和胶原膜填充骨缺损,以及术后 6 个月、1 年和 5 年定期进行 CT 扫描监测;所有监测均显示无复发。成功的因素包括谨慎的手术、适当的生物材料使用和持续的随访。本病例成功的主要限制因素是什么?限制因素包括上皮下结缔组织移植的潜在并发症,如囊肿发展。本报告强调了精心选择患者和评估牙周表型以尽量降低风险的重要性。持续的随访对于检测复发和其他问题至关重要。
{"title":"Epithelial cyst following subepithelial connective tissue graft: A case report.","authors":"Julien de Paula, Luise A B da Silva, Mariane A S Wayar, Eduardo B Campagnoli, Fábio A Dos Santos","doi":"10.1002/cap.10284","DOIUrl":"https://doi.org/10.1002/cap.10284","url":null,"abstract":"<p><strong>Background: </strong>Various surgical approaches have been employed to manage gingival recession, including subepithelial connective tissue grafting, which has yielded favorable outcomes.</p><p><strong>Methods and results: </strong>We present the case of a 17-year-old patient who developed gingival recession on tooth #6 following an esthetic crown lengthening procedure. The recession was treated with a subepithelial connective tissue graft; however, this case details the occurrence of two epithelial cysts adjacent to the region subjected to the surgical procedure, 6 months after surgery. The treatment involved periodontal surgical intervention, during which the lesions were completely excised and the associated osseous defect was filled using an inorganic bovine bone matrix along with a collagen membrane. The healing progressed without any complications. Histopathological analysis revealed the presence of cystic lesions, which were characterized by a cystic cavity lined with stratified orthokeratinized epithelium with cuboidal cells in some areas surrounded by fibrous connective tissue. The patient's progress was monitored through tomography performed 6 months, 1 year, and 5 years post-procedure, all of which demonstrated the absence of any signs of lesion recurrence.</p><p><strong>Conclusion: </strong>This case study emphasizes the effectiveness and predictability of subepithelial connective tissue grafting in the treatment of gingival recession. However, dental professionals should be cautious about the potential risk of gingival recession following esthetic crown lengthening procedures and recognize the potential complications associated with subepithelial connective tissue grafting, such as the observed development of epithelial cysts in this specific case.</p><p><strong>Key points: </strong>Why is this case new information? We present a case of an epithelial cyst following a subepithelial connective tissue graft, which resulted in buccal cortical bone resorption. The treatment involved excisional biopsy and the use of an inorganic bovine bone matrix with a collagen membrane. What are the keys to the successful management of this case? Successful treatment included periodontal surgery, bone defect filling using an inorganic bovine bone matrix and a collagen membrane, and regular monitoring with CT scans at 6 months, 1 year, and 5 years post-surgery; all showed no recurrence. Success factors included careful surgery, appropriate biomaterial usage, and ongoing follow-up. What are the primary limitations to success in this case? The limitations involve potential complications from subepithelial connective tissue grafting such as cyst development. This report stresses the importance of meticulous patient selection and periodontal phenotype evaluation to minimize risks. Continuous follow-up is critical to detect recurrence and other issues.</p>","PeriodicalId":55950,"journal":{"name":"Clinical Advances in Periodontics","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140013770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digital assessment of supracrestal tissue attachment and its correlation with dentogingival components. 嵴上组织附着的数字化评估及其与牙龈成分的相关性。
IF 0.7 Q3 Medicine Pub Date : 2024-02-13 DOI: 10.1002/cap.10280
Hesham H Abdulkarim, Nathan M Antoine, Mary Ying-Fang Wang, Elio Reyes Rosales, D Douglas Miley

Background: The aim of this study is to measure, in vivo, the supracrestal tissue attachment dimensions (STADs) by means of a noninvasive digital method and to investigate the association between STADs and gingival thickness (GT), tooth position, tooth length, tooth width, keratinized tissue width (KTW), buccal bone thickness (BBT), and bone crest (BC) level.

Methods: Nineteen periodontally healthy subjects who previously received full mouth periodontal charting, cone beam computed tomography, and intraoral scan for the purpose of implant planning were included in the study. A digital imaging software was used for the superimposition of Digital Imaging and Communications in Medicine and stereolithography files, along with hard and soft tissue measurements. Pearson's correlation and ANOVA statistical analyses were used to investigate potential trends between STADs and other dentogingival components.

Results: A total of 203 teeth were assessed, with an average STADs of 2.05 mm (±0.99 mm). STADs were larger in mandibular than maxillary teeth (p-value <0.001) and decreased from anterior to posterior teeth. STADs exhibited an inverse relationship with BBTs and GTs (p-value <0.001) and the KTW (p-value = 0.05). Positive correlations were found between GT and BBT (p-value <0.001), whereas both were negatively correlated with the distance between the cementoenamel junction and BC (p-values 0.019 and 0.006, respectively) and positively correlated with KTW (p-value <0.001).

Conclusions: This study highlighted the dynamic nature of STA relative to tooth position. Additionally, it explored the intricate relationships of STADs with various dentogingival components.

Key points: To the best of the authors' knowledge, this study represents the first application of CBCTs, intraoral scans, and clinical probe depths for noninvasive supracrestal tissue attachment measurements. This study advocates for a personalized assessment of supracrestal attachments, incorporating tooth position and other dentogingival components. The study emphasizes the importance for practitioners to consider the specific patient gingival phenotypes during restorative or surgical planning to avoid adverse outcomes.

研究背景本研究的目的是通过无创数字方法测量牙龈上组织附着尺寸(STADs),并研究STADs与牙龈厚度(GT)、牙齿位置、牙齿长度、牙齿宽度、角化组织宽度(KTW)、颊骨厚度(BBT)和骨嵴水平(BC)之间的关联:研究对象包括 19 名牙周健康的受试者,他们曾接受过全口牙周造影、锥形束计算机断层扫描和口内扫描,目的是进行种植规划。研究人员使用数字成像软件将医学数字成像和通信、立体光刻文件以及软硬组织测量结果叠加在一起。使用皮尔逊相关性和方差分析来研究 STAD 和其他牙龈成分之间的潜在趋势:共评估了 203 颗牙齿,STADs 平均值为 2.05 mm (±0.99 mm)。下颌牙的 STADs 大于上颌牙(P 值 结论:STADs 在下颌牙比上颌牙大:本研究强调了 STA 相对于牙齿位置的动态性质。此外,研究还探讨了 STAD 与各种牙龈成分之间错综复杂的关系:据作者所知,这项研究首次将 CBCT、口内扫描和临床探针深度应用于无创冠上组织附着测量。这项研究提倡对牙冠上附着体进行个性化评估,将牙齿位置和其他牙龈成分纳入其中。该研究强调了从业人员在制定修复或手术计划时考虑患者具体牙龈表型的重要性,以避免不良后果的发生。
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引用次数: 0
Microsurgical approach for the management of gingival cleft: A case series and decision-making process. 显微手术治疗龈裂:病例系列和决策过程。
IF 0.7 Q3 Medicine Pub Date : 2024-01-19 DOI: 10.1002/cap.10277
Saravanan Sampoornam Pape Reddy, Balaji Manohar

Background: Gingival clefts, once known as "Stillman's Cleft", now considered an obsolete phenomenon, cannot be neglected in clinical practice, especially when it is persistent and epithelialized. The attached gingiva and alveolar mucosa are composed of epithelial layers with subjacent connective tissue. Gingival clefts, notwithstanding their intrinsic differences, may exhibit keratinized or non-keratinized tissue. Coupled with additional risk factors, it can result in progressive attachment loss and gingival recession.

Methods: Two cases with three distinct types of gingival clefts were described. Case 1 was identified as having a 2 mm white cleft coupled with lack of attached gingiva, while Case 2 was described as having a 3 mm white and red cleft which were treated with gingival cleft approximation subsequent to connective tissue grafting, non-surgical periodontal therapy and cleft approximation, respectively. The diagnostic confirmation was verified using an operating microscope set at a magnification of 5×, while the subsequent surgical stages were carried out with a magnification of 8×. These treatments yielded complete elimination and closure of the gingival clefts in addition to increased width of attached gingiva and soft tissue phenotype in Case 1 where bilaminar approach was utilized. The three clefts were effectively addressed using an operating microscope for both non-surgical and surgical interventions in the cleft management.

Results: All the three clefts exhibited complete elimination and closure of the gingival cleft. At 3 years follow up, there was reduction of the probing depth (1 mm) and attachment gain (1 mm) in all the three clefts. There was increase in width of attached gingiva to 3 mm and increase in soft tissue thickness in Case 1, where connective tissue graft was utilized. As microsurgical treatment approach was employed, the patients did not manifest with any intra-operative or postoperative complications. The first case showed the presence of soft tissue bulk at the treated site warranting debulking at 12 months postoperatively. The stability of the width of attached gingiva was maintained over the course of the 3-year follow-up period. The use of a microsurgical method in these settings enhances the predictability of outcomes than a macrosurgical approach.

Conclusions: The utilization of microsurgical techniques for the closure of gingival clefts allows for the accurate and meticulous insertion and placement of grafts, resulting in improved outcomes and enhanced aesthetic results. These techniques also minimize tissue trauma and postoperative discomfort. The treatment technique should be personalized to the individual's specific needs, considering factors such as type and extent of cleft, etiology and amount of attached gingiva. Nonetheless, microsurgical approaches for such cases are no more a discretion but an obligation.

<
背景:龈裂曾被称为 "Stillman's Cleft",现已被认为是一种过时的现象,但在临床实践中不容忽视,尤其是当龈裂持续存在并上皮化生时。附着的牙龈和牙槽粘膜由上皮层和邻近的结缔组织组成。龈裂尽管有其内在差异,但可能表现为角质化或非角质化组织。再加上其他风险因素,会导致逐渐丧失附着力和牙龈退缩:方法:本文描述了两个具有三种不同类型龈裂的病例。方法:描述了两个具有三种不同类型龈裂的病例。病例 1 被确定为 2 毫米的白色龈裂,同时缺乏附着龈;病例 2 被描述为 3 毫米的白色和红色龈裂,分别在结缔组织移植、非手术牙周治疗和龈裂逼近术后进行了龈裂逼近术。诊断确认使用放大 5 倍的手术显微镜进行,随后的手术阶段使用放大 8 倍的显微镜进行。在采用双层法的病例 1 中,除了附着龈宽度和软组织表型增加外,这些治疗方法还彻底消除和封闭了龈沟。使用手术显微镜对这三个龈裂进行了有效的非手术和手术治疗:结果:所有三个唇裂的龈沟都已完全消除和闭合。在 3 年的随访中,所有三个龈裂的探诊深度都减少了 1 毫米,附着增量也减少了 1 毫米。在使用结缔组织移植的病例 1 中,附着的牙龈宽度增加到 3 毫米,软组织厚度增加。由于采用了显微外科治疗方法,患者没有出现任何术中或术后并发症。第一个病例在术后 12 个月时发现治疗部位的软组织增厚,需要进行剥离。在 3 年的随访期间,附着牙龈的宽度保持稳定。在这些情况下使用显微外科方法比使用大手术方法更能预测结果:结论:使用显微外科技术封闭龈裂,可以准确、细致地插入和放置移植物,从而改善治疗效果,提高美学效果。这些技术还能最大限度地减少组织创伤和术后不适。治疗技术应根据个人的具体需求进行个性化设计,并考虑到裂隙的类型和范围、病因和附着牙龈的数量等因素。尽管如此,对这类病例采用显微外科方法已不再是一种酌处权,而是一种义务:要点:在常规牙周检查中不应忽视龈裂的识别。要点:在常规牙周检查中不应忽视龈裂的识别,在完成第一阶段治疗后应观察龈裂的临床变化。只有 "白色 "龈沟才需要明确的手术治疗。未经治疗的龈沟会导致牙根敏感、根龋和边缘组织衰退。
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引用次数: 0
Uncovering of transplanted connective tissue graft: Clinical and histological evaluation. 揭开移植的结缔组织移植物:临床和组织学评估
IF 0.7 Q3 Medicine Pub Date : 2024-01-19 DOI: 10.1002/cap.10278
Adriano Fratini, Leonardo Mancini, Margherita G Liguori, Stefano Gotti, Enrico Marchetti

Background: Periodontal plastic surgery aims to restore recessions and dehiscence around teeth and implants. Several techniques, such as subepithelial connective tissue graft (CTG), were proposed with the main outcome of improving volume and root coverage. Nevertheless, this surgery might not improve the keratinized tissue width. Thus, the primary aim of this case report was to describe the possible increase in keratinized tissue after a subepithelial CTG and simultaneously use the previously harvested graft as a source for covering an adjacent tooth.

Methods: A 38-year-old patient presented brushing discomfort 2 years after undergoing periodontal plastic surgery with a CTG from the palate to cover a recession. Despite the increased thickness of the soft tissue, brushing discomfort was not reduced because the tissue quality remained unchanged. Therefore, a surgical procedure in the area of teeth 3.2-3.4 was performed to remove the more superficial masticatory mucosa and to induce keratinization of the previously grafted connective tissue.

Results: After 6 months, the epithelium appears to be clinically and histologically keratinized, with characteristics comparable to those of the original tissue.

Conclusions: The connective tissue grafted maintains the potential to induce keratinization over time, if it is exposed.

Key points: Why is this case new information? To the best of our knowledge, this is the first case report in the literature with a histological evaluation in a human of the tissue grafted exposed after 2 years. What are the keys to successful management of this case? The graft covered by the alveolar mucosa did not induce keratinization of the epithelium of the overlying mucosa. What are the primary limitations to success in this case? The main limitation of this study is that it is a singular case report.

背景:牙周整形手术旨在修复牙齿和种植体周围的凹陷和开裂。上皮下结缔组织移植(CTG)等几种技术被提出,其主要结果是改善体积和牙根覆盖。然而,这种手术可能无法改善角化组织的宽度。因此,本病例报告的主要目的是描述上皮下结缔组织移植术后角化组织可能增加的情况,并同时利用之前采集的移植组织作为覆盖邻牙的来源:一名 38 岁的患者在接受牙周整形手术 2 年后出现了刷牙不适的症状,该手术使用了上颚 CTG 来覆盖衰退的牙齿。尽管软组织的厚度增加了,但由于组织质量保持不变,刷牙不适感并未减轻。因此,在 3.2-3.4 号牙齿区域进行了一次手术,切除了较浅的咀嚼粘膜,并促使之前移植的结缔组织角质化:结果:6 个月后,上皮在临床和组织学上出现角化,其特征与原始组织相当:结论:移植的结缔组织如果暴露在外,随着时间的推移仍有可能诱导角化:为什么本病例是新信息?据我们所知,这是文献中第一例对人体两年后暴露的移植组织进行组织学评估的病例报告。成功处理该病例的关键是什么?被牙槽粘膜覆盖的移植组织没有引起覆盖粘膜上皮的角化。本病例成功的主要限制因素是什么?本研究的主要局限性在于它只是一份单一的病例报告。
{"title":"Uncovering of transplanted connective tissue graft: Clinical and histological evaluation.","authors":"Adriano Fratini, Leonardo Mancini, Margherita G Liguori, Stefano Gotti, Enrico Marchetti","doi":"10.1002/cap.10278","DOIUrl":"https://doi.org/10.1002/cap.10278","url":null,"abstract":"<p><strong>Background: </strong>Periodontal plastic surgery aims to restore recessions and dehiscence around teeth and implants. Several techniques, such as subepithelial connective tissue graft (CTG), were proposed with the main outcome of improving volume and root coverage. Nevertheless, this surgery might not improve the keratinized tissue width. Thus, the primary aim of this case report was to describe the possible increase in keratinized tissue after a subepithelial CTG and simultaneously use the previously harvested graft as a source for covering an adjacent tooth.</p><p><strong>Methods: </strong>A 38-year-old patient presented brushing discomfort 2 years after undergoing periodontal plastic surgery with a CTG from the palate to cover a recession. Despite the increased thickness of the soft tissue, brushing discomfort was not reduced because the tissue quality remained unchanged. Therefore, a surgical procedure in the area of teeth 3.2-3.4 was performed to remove the more superficial masticatory mucosa and to induce keratinization of the previously grafted connective tissue.</p><p><strong>Results: </strong>After 6 months, the epithelium appears to be clinically and histologically keratinized, with characteristics comparable to those of the original tissue.</p><p><strong>Conclusions: </strong>The connective tissue grafted maintains the potential to induce keratinization over time, if it is exposed.</p><p><strong>Key points: </strong>Why is this case new information? To the best of our knowledge, this is the first case report in the literature with a histological evaluation in a human of the tissue grafted exposed after 2 years. What are the keys to successful management of this case? The graft covered by the alveolar mucosa did not induce keratinization of the epithelium of the overlying mucosa. What are the primary limitations to success in this case? The main limitation of this study is that it is a singular case report.</p>","PeriodicalId":55950,"journal":{"name":"Clinical Advances in Periodontics","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139492782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of single gingival recessions using biofunctionalized collagen matrix: A case series 使用生物功能化胶原基质治疗单个牙龈凹陷:病例系列。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-12-12 DOI: 10.1002/cap.10276
Amanda Rossato, Manuela Maria Viana Miguel, Ana Carolina Ferreira Bonafé, Ingrid Fernandes Mathias-Santamaria, Marcelo Pereira Nunes, Mauro Pedrine Santamaria

Background

Connective tissue graft substitutes have been used widely to overcome autogenous graft limitations. Nevertheless, they do not provide comparable results in the treatment of periodontal and peri-implant soft tissue defects. Based on the principles of tissue-engineered materials, injectable platelet-rich fibrin (i-PRF) has been combined with collagen matrices (CMs) to enhance their clinical efficacy. To the best of our knowledge, this is the first case series demonstrating the use of i-PRF for the biofunctionalization of a volume-stable collagen matrix (VCMX) as an adjunct to coronally advanced flap (CAF) to treat single gingival recession (GR) defects.

Methods & Results

The study included 10 patients. Bleeding on probing, probing depth, GR height, clinical attachment level, esthetics, and dentin hypersensitivity were evaluated. After 6 months, a significant GR reduction (RecRed: 2.15 ± 0.7 mm; p = 0.005) and percentage of root coverage (% RC) of 81.13% were observed. Additionally, 40% of the sites showed complete root coverage. Gingival thickness increased 0.64 mm. Patient-centered evaluations demonstrated dentin hypersensitivity and esthetics improvements by the end of follow-up.

Conclusion

VCMX biofunctionalized with i-PRF associated with CAF technique showed promising clinical outcomes in the treatment of single RT1 GR defects.

背景:结缔组织移植替代物已被广泛用于克服自体移植的局限性。然而,它们在治疗牙周和种植体周围软组织缺损方面的效果并不理想。根据组织工程材料的原理,可注射富血小板纤维蛋白(i-PRF)与胶原基质(CMs)相结合,以提高其临床疗效。据我们所知,这是第一例使用 i-PRF 对体积稳定型胶原基质(VCMX)进行生物功能化,并将其作为冠状前移皮瓣(CAF)治疗单个牙龈退缩(GR)缺损的系列病例:研究包括 10 名患者。对探诊出血、探诊深度、GR 高度、临床附着水平、美学和牙本质过敏进行了评估。6 个月后,观察到牙根高度明显降低(RecRed:2.15 ± 0.7 mm;p = 0.005),牙根覆盖率(% RC)达到 81.13%。此外,40% 的部位显示牙根完全覆盖。牙龈厚度增加了 0.64 毫米。以患者为中心的评估结果表明,在随访结束时,牙本质过敏症和美观度均有所改善:结论:在治疗单个 RT1 GR 缺损时,i-PRF 与 CAF 技术结合的 VCMX 生物功能化显示出良好的临床效果。
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引用次数: 0
Surgical reconstruction of peri-implantitis with adjunctive antimicrobial photodynamic therapy: A case report with 5-year follow-up 辅助抗菌光动力治疗种植体周围炎的手术重建:5年随访1例。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-11-29 DOI: 10.1002/cap.10275
Ardavan Etemadi, Hamoun Sabri, Mahsa Enssi
<div> <section> <h3> Background</h3> <p>Peri-implantitis poses a significant challenge in dental implantology due to its potential to result in the loss of supporting tissue around dental implants. Surgical reconstruction is often recommended for intrabony defects, accompanied by various adjunctive therapies, such as antimicrobial photodynamic therapy (aPDT), for bacterial decontamination. However, the long-term efficacy of such treatments remains unclear.</p> </section> <section> <h3> Methods</h3> <p>This clinical report presents a case of peri-implantitis management in a healthy 55-year-old male using guided bone regeneration principles and surface decontamination via aPDT. The patient exhibited peri-implantitis with probing pocket depths (PPD) of 7 mm at buccal sites, 5 mm at palatal sites, and significant bone loss around implant #12. The reconstructive approach involved preservation of the existing implant and following a non-submerged healing protocol. The surgical phase included meticulous debridement, chemical detoxification with hydrogen peroxide, and aPDT using a 670 nm diode laser with methylene blue as the photosensitizer. Xenogenic bone graft and a resorbable collagen membrane were applied and the patient was followed up to through a 5-year period.</p> </section> <section> <h3> Results</h3> <p>Postsurgery the patient exhibited normal healing, and long-term follow-up at 5 years showed reduced PPD (2 mm buccally, 3 mm mid-palatally), complete intrabony defect fill, and stable bone levels, indicating successful treatment.</p> </section> <section> <h3> Conclusions</h3> <p>This case report demonstrates the potential long-term success of a reconstructive approach with adjunctive aPDT in peri-implantitis management. However, it highlights the need for standardized protocols and further clinical trials to establish the clinical benefits of aPDT in surgical reconstruction of peri-implantitis defects, serving as valuable pilot data for future research.</p> </section> <section> <h3> Key points</h3> <div><b>Why is this case new information?</b> <ul> <li>Provides a rare 5-year insight into peri-implantitis intrabony defect reconstruction, offering extended success and outcomes not frequently documented.</li> <li>Demonstrates the efficacy of aPDT with a 670-nm diode laser in achieving successful long-term outcomes, contributing
背景:种植体周围炎是牙种植学的一个重大挑战,因为它可能导致牙种植体周围支持组织的损失。手术重建通常被推荐用于骨内缺陷,并伴有各种辅助治疗,如抗菌光动力治疗(aPDT),用于细菌净化。然而,这些治疗方法的长期疗效尚不清楚。方法:本临床报告报告一例55岁健康男性,采用引导骨再生原则和aPDT表面去污治疗种植体周围炎。患者表现为种植体周围炎,颊部探查袋深度为7 mm,腭部探查袋深度为5 mm,种植体12号周围明显骨质流失。重建方法包括保留现有种植体并遵循非浸没愈合方案。手术阶段包括细致的清创,过氧化氢化学解毒,以及使用670 nm二极管激光以亚甲基蓝作为光敏剂的aPDT。应用异种骨移植和可吸收胶原膜,随访5年。结果:术后患者愈合正常,长期随访5年,PPD下降(颊部2mm,腭中部3mm),骨内缺损完全填充,骨水平稳定,治疗成功。结论:本病例报告表明,辅助aPDT重建方法在种植体周围炎治疗中具有潜在的长期成功。然而,它强调需要标准化的方案和进一步的临床试验来确定aPDT在手术重建种植体周围炎缺陷中的临床益处,为未来的研究提供有价值的先导数据。亮点:为什么这个案例是新信息?提供了一个罕见的5年洞察种植体周围骨内缺损重建,提供延长的成功和结果不经常记录。证明了670nm二极管激光aPDT在实现成功的长期预后方面的有效性,为现有文献提供了有价值的证据。成功处理该病例的关键:成功包括最初的非手术清创,随后是重建策略,包括引导骨再生和通过aPDT进行表面净化。长期成功取决于患者遵守常规口腔卫生,强调重建后坚持预防措施的重要性,以尽量减少复发风险。在这种情况下,成功的主要限制是什么?光敏剂吸收的可变性以及组织损伤和细菌耐药性等潜在风险对aPDT的有效性提出了挑战。现有关于aPDT治疗种植体周围炎的文献在方法、激光参数、随访时间等方面缺乏标准化,难以建立一个普遍接受的方案。
{"title":"Surgical reconstruction of peri-implantitis with adjunctive antimicrobial photodynamic therapy: A case report with 5-year follow-up","authors":"Ardavan Etemadi,&nbsp;Hamoun Sabri,&nbsp;Mahsa Enssi","doi":"10.1002/cap.10275","DOIUrl":"10.1002/cap.10275","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Background&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Peri-implantitis poses a significant challenge in dental implantology due to its potential to result in the loss of supporting tissue around dental implants. Surgical reconstruction is often recommended for intrabony defects, accompanied by various adjunctive therapies, such as antimicrobial photodynamic therapy (aPDT), for bacterial decontamination. However, the long-term efficacy of such treatments remains unclear.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This clinical report presents a case of peri-implantitis management in a healthy 55-year-old male using guided bone regeneration principles and surface decontamination via aPDT. The patient exhibited peri-implantitis with probing pocket depths (PPD) of 7 mm at buccal sites, 5 mm at palatal sites, and significant bone loss around implant #12. The reconstructive approach involved preservation of the existing implant and following a non-submerged healing protocol. The surgical phase included meticulous debridement, chemical detoxification with hydrogen peroxide, and aPDT using a 670 nm diode laser with methylene blue as the photosensitizer. Xenogenic bone graft and a resorbable collagen membrane were applied and the patient was followed up to through a 5-year period.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Postsurgery the patient exhibited normal healing, and long-term follow-up at 5 years showed reduced PPD (2 mm buccally, 3 mm mid-palatally), complete intrabony defect fill, and stable bone levels, indicating successful treatment.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusions&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This case report demonstrates the potential long-term success of a reconstructive approach with adjunctive aPDT in peri-implantitis management. However, it highlights the need for standardized protocols and further clinical trials to establish the clinical benefits of aPDT in surgical reconstruction of peri-implantitis defects, serving as valuable pilot data for future research.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Key points&lt;/h3&gt;\u0000 \u0000 &lt;div&gt;&lt;b&gt;Why is this case new information?&lt;/b&gt;\u0000 \u0000 &lt;ul&gt;\u0000 \u0000 &lt;li&gt;Provides a rare 5-year insight into peri-implantitis intrabony defect reconstruction, offering extended success and outcomes not frequently documented.&lt;/li&gt;\u0000 \u0000 &lt;li&gt;Demonstrates the efficacy of aPDT with a 670-nm diode laser in achieving successful long-term outcomes, contributing ","PeriodicalId":55950,"journal":{"name":"Clinical Advances in Periodontics","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cap.10275","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A pattern of peri-implantitis affecting middle implants in 3-implant splinted prostheses. 三种植体夹板假体中影响中间种植体的种植体周围炎模式。
IF 0.7 Q3 Medicine Pub Date : 2023-11-27 DOI: 10.1002/cap.10274
Braedan Rj Prete, Michael Aj Silva, Brian C Wong, Douglas A Deporter

Background: Previous investigators have noted an increased risk of crestal bone loss and failure of the middle implant of 3-implant-splinted (3-IS) fixed dental prostheses (FDPs). Possible causes have included ill-fitting prostheses, unhygienic prosthetic contours, and discrepancies in prosthetic platform heights.

Methods & results: We identified four cases in which the middle implant of a 3-IS multiunit FDP suffered advanced bone loss, ultimately leading to implant removal. While more than one possible risk for implant failure existed in each case, a common thread was that the prosthetic platform of the middle implant for all patients was coronally positioned relative to the corresponding mesial and/or distal implants.

Conclusions: Splinting three adjacent implants into one prosthesis may add risk for a variety of reasons possibly including small differences in the heights of the three prosthetic tables.

Key points: Why are these cases new information? Our observations suggest that discrepancies between implant prosthetic platforms supporting 3-implant splinted, multiunit FDPs may be an added risk factor for middle implant failure. What are the keys to successful management of these cases? It is possible that small differences in apico-coronal implant positioning with 3-implant splinted multiunit FDPs may affect the success of the middle implants. What are the primary limitations to success in these cases? There is limited literature involving precise protocols and long-term outcomes of 3-implant splinted implant restorations. Studies comparing 3-implant splinted FDPs to other configurations are needed.

背景:以前的研究者已经注意到3-种植体夹板(3-IS)固定义齿(FDPs)的嵴骨丢失和中间种植体失败的风险增加。可能的原因包括不合适的假体、不卫生的假体轮廓和假体平台高度的差异。方法与结果:我们确定了4例3-IS多单元FDP的中间种植体出现晚期骨质流失,最终导致种植体移除。虽然每种情况下都存在多种可能的种植体失败风险,但一个共同点是,所有患者的中间种植体的假体平台相对于相应的近端和/或远端种植体是冠状定位的。结论:将三个相邻的假体夹板固定在一个假体中可能会增加风险,原因多种多样,可能包括三个假体台面高度差异较小。重点:为什么这些案例是新信息?我们的观察结果表明,支持3种植体夹板的种植体假体平台之间的差异,多单元fdp可能是中期种植体失败的一个额外危险因素。成功管理这些病例的关键是什么?三种植体夹板多单元FDPs的尖冠状种植体定位的微小差异可能会影响中间种植体的成功。在这些案例中,成功的主要限制是什么?关于三种植体夹板种植体修复的精确方案和长期结果的文献有限。需要对3种植体夹板fdp与其他配置进行比较研究。
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引用次数: 0
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Clinical Advances in Periodontics
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