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Vestibular tunnel approach in restoring non-carious cervical lesion gingival recessions with combination of bioceramics and collagen matrix: A case report with a 1-year follow-up 前庭隧道入路联合生物陶瓷和胶原基质修复非龋齿宫颈病变牙龈衰退1例,随访1年
IF 0.7 Q3 Medicine Pub Date : 2022-08-05 DOI: 10.1002/cap.10222
Kai-Chiao Joe Chang, John H. Mumford, Alex Long, Vinh H. Ton

Introduction

Non-carious cervical lesions (NCCLs) can compromise the integrity to both hard and soft tissues of teeth. This case report introduces a novel interdisciplinary technique by utilizing bioceramics-based cement (BBC) and porcine collagen matrix (CM) to reconstruct the dentogingival complex where enamel, dentin, and soft tissues were involved.

Case presentation

A 38-year-old healthy male was referred to the periodontics department for gingival recessions teeth #27–29 and a deep (NCCL) on the facial (F) #28 involving the loss of the cementoenamel junction (CEJ). The F #28 was restored with BBC according to manufacturing instructions. Soft tissues of #27–29 were simultaneously augmented with two CM strips via a coronally advanced tunnel utilizing suspended sutures. At the 6-month follow-up, approximately 100% root coverages were obtained for #27 and 29. The F #28 gingival tissue stabilized at the anticipated level of maximum root coverage (MRC), 1 mm apical to the coronally displaced CEJ. The exposed layer of BBC, F #28, was veneered with resin-modified glass ionomer to re-establish the original position of the CEJ. At the one-year follow-up visit root coverage for #28 remained stable and probing depths remained unchanged at 2 mm F #27–29. A sectional cone beam computed tomography scan illustrated the BBC restoration remained intact and well adapted.

Conclusion

The 12-month follow-up illustrated that the BBC may be a viable restorable material while performing simultaneous gingival grafting with CM in deep NCCLs with gingival recessions.

Key points

Why is this case new information?
  • A novel approach treating the deep non-carious cervical lesion with BBC and CM.
What are the keys to successful management of this case?
  • The BBC placement needs to be flat.
  • Secure the surgical site with non-resorbable suspensory sutures fixed by flowable composite.
What are the primary limitations to success in this case?
引言非龋性宫颈病变(NCCL)会损害牙齿硬组织和软组织的完整性。本病例报告介绍了一种新的跨学科技术,利用生物陶瓷基水泥(BBC)和猪胶原基质(CM)重建涉及牙釉质、牙本质和软组织的牙本质复合体。病例介绍一名38岁的健康男性因牙龈退缩27–29号牙齿和面部(F)28号深层(NCCL)涉及牙骨质-上皮连接(CEJ)缺失而被转诊至牙周病科。F#28是由英国广播公司根据制造说明修复的。27–29号软组织通过使用悬吊缝线的冠状动脉超前隧道,同时用两条CM条进行增强。在6个月的随访中,27号和29号获得了大约100%的根系覆盖率。F#28牙龈组织稳定在最大牙根覆盖率(MRC)的预期水平,距离冠状移位的CEJ顶端1mm。用树脂改性的玻璃离聚物对BBC的暴露层F#28进行贴面,以重新建立CEJ的原始位置。在为期一年的随访中,28号的根部覆盖率保持稳定,探测深度在2 mm F#27-29处保持不变。截面锥束计算机断层扫描显示,英国广播公司的修复体完好无损,适应良好。结论12个月的随访表明,BBC可能是一种可行的修复材料,同时在伴有牙龈退缩的深层NCCL中与CM进行牙龈移植。要点为什么这个案例是新信息?BBC和CM治疗宫颈深部非龋性病变的新方法。成功治疗该病例的关键是什么?BBC的位置需要平坦。用可流动复合材料固定的不可吸收悬吊缝线固定手术部位。在这种情况下,成功的主要限制是什么?成功的主要限制是血液水分控制,这可能会限制通过入口放置胶原基质条。
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引用次数: 1
The management of an oral pyogenic granuloma around osseointegrated dental implants 牙种植体周围口腔化脓性肉芽肿的处理
IF 0.7 Q3 Medicine Pub Date : 2022-07-31 DOI: 10.1002/cap.10219
Danielle K. Burgess, Paul A. Levi Jr., David M. Kim

Introduction

Oral pyogenic granulomas (PGs) presenting in association with dental implants are uncommon occurrences. While tooth-associated PGs are well-documented in the literature, there are only seven case reports with biopsy-confirmed diagnoses of PG related to dental implants. This case report details the treatment of an intraoral PG related to dental implants that had been osseointegrated and asymptomatic for 10 years.

Case Presentation

A 39-year-old female presented with a hyperplastic erythematous mass that encompassed the dental implants in the position of the maxillary central incisors. Surgical exploration of the site revealed nonintegrated, particulate bone material distributed throughout the peri-implant tissues approximating the granuloma. Treatment involved surgical excision of the lesion, elimination of all nonintegrated bone material, and implant surface debridement. Laser therapy was later used to manage a recurrence. Histology of the biopsied tissue confirmed the diagnosis of PG and described the presence of multiple exogenous, refractile, particulate materials in the specimen.

Conclusion

The combination of surgical excision, implant debridement, and conservative laser therapy resulted in the elimination of a dental implant-related PG and successful soft tissue management. The localized presence of nonintegrated particulate bone material surrounding the granuloma appears to have functioned as a chronic irritant to the peri-implant soft tissues over time and is likely, along with oral bacteria, the primary etiological agents.

Key points

Why is this case new information?
  • There is a paucity of reports describing the management of dental implant-related pyogenic granulomas especially in the esthetic region. The present case demonstrates that particulate bone materials used in guided bone regeneration have the capacity to behave as a low-grade irritant to the gingival tissues. It also demonstrates the successful elimination of the tissues and management of the peri-implant soft tissues for an esthetic result.
What are the keys to successful management of this case?
  • The key to successful management of this case was adequate removal of the exogenous irritant, proper implant surface debridement, and decontamination and adequate gingivoplasty to remove all residual hyperplastic gr
口腔化脓性肉芽肿(pg)与种植牙相关是罕见的。虽然与牙齿相关的PG在文献中有很好的记录,但只有7例活检确诊的PG与牙种植体有关。本病例报告详细介绍了与牙种植体相关的口腔内PG的治疗,该PG已骨整合且无症状10年。病例介绍:一名39岁的女性,在上颌中切牙的位置出现了一个增生的红斑肿块,包围了种植牙。手术探查发现非完整的颗粒状骨物质分布在接近肉芽肿的种植体周围组织中。治疗包括手术切除病变,清除所有未整合的骨材料,以及种植体表面清创。激光治疗后来被用于治疗复发。活检组织的组织学证实了PG的诊断,并描述了标本中存在多种外源性,可折射的颗粒物质。结论手术切除、种植体清创和保守性激光治疗可消除种植体相关的PG,并成功处理软组织。肉芽肿周围局部存在的非整合颗粒状骨物质,随着时间的推移,似乎对种植体周围软组织具有慢性刺激作用,并可能与口腔细菌一起成为主要病因。为什么这个案例是新信息?有一个缺乏的报告描述管理的牙种植体相关的化脓性肉芽肿,特别是在审美区域。本案例表明,用于引导骨再生的颗粒骨材料具有对牙龈组织产生低度刺激的能力。它也证明了组织的成功消除和种植体周围软组织的管理,以获得美观的结果。成功管理这个案例的关键是什么?成功处理本病例的关键是充分去除外源性刺激,适当的种植体表面清创,去污和充分的牙龈成形术去除所有残留的增生性肉芽肿组织。此外,患者教育和适当的口腔卫生指导对于该区域的适当愈合和维护是重要的。在这种情况下,成功的主要限制是什么?PGs的临床边界的模糊性使得它具有挑战性,以保证完全切除超出病灶的基础,导致复发。
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引用次数: 0
Autologous blood products: Usage and preparation protocols 自体血液制品:使用和制备方案
IF 0.7 Q3 Medicine Pub Date : 2022-07-30 DOI: 10.1002/cap.10221
Archontia Palaiologou, Francis Keeling

Focused clinical question

What are the appropriate preparation protocols for autologous blood products to support their clinical utilization?

Summary

Autologous blood products provide a unique clinical benefit. Their popularity among the professions is growing. However, as this is a rapidly evolving field, multiple modalities are presented within the literature. Frequently there is no demonstrated superiority to previous iterations. This brief review attempts to offer a concise chronology on their evolution, preparation, and where possible, evidence to support their clinical utilization.

Conclusions

The field of autologous blood products is expanding rapidly. These products appear to yield variable clinical benefits in specific indications. However, evidence supporting their universal application is scant, and the superiority of one formulation versus another is yet to be demonstrated.

重点临床问题自体血液制品的适当制备方案是什么,以支持其临床应用?自体血液制品具有独特的临床益处。他们在各行各业中越来越受欢迎。然而,由于这是一个快速发展的领域,文献中提出了多种模式。通常没有证明比以前的迭代更优越。这篇简短的综述试图提供一个简明的年表的演变,准备,并在可能的情况下,证据支持其临床应用。结论自体血液制品领域正在迅速扩大。这些产品似乎在特定适应症中产生不同的临床益处。然而,支持其普遍应用的证据很少,一种配方相对于另一种配方的优越性还有待证明。
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引用次数: 0
Iatrogenic cold urticaria induced by tetrafluoroethane cryosurgery for gingival depigmentation: A rare case report 四氟乙烷冷冻手术治疗牙龈色素沉着致医源性冷性荨麻疹1例
IF 0.7 Q3 Medicine Pub Date : 2022-07-27 DOI: 10.1002/cap.10217
Thamil Selvan Muthuraj, Puja Sarkar, Murugan Jeyasree Renganath, Pillaiyar Gurusamy Senthilkumaran

Introduction

Gingival depigmentation procedure has gained widespread popularity in the recent years due to increased esthetic demands among patients. Among the various depigmentation procedures, cryosurgery is inexpensive and straightforward method. This case report discusses a rare complication associated with tetrafluoroethane (TFE) cryosurgical depigmentation method.

Case Presentation

A 27-year-old systemically healthy male patient reported with the complaint of esthetic concerns associated with gingival melanin pigmentation. Cryosurgery with TFE was planned for the maxillary first quadrant. The patient developed angioedema immediately after exposure to the TFE cryogen during the procedure. Cold urticaria was considered, and the patient was prescribed nonsedating antihistamines for a week. One month follow-up showed completely healed and depigmented gingiva without any recession or attachment loss.

Conclusions

TFE cryosurgery depigmentation was found to be an effective depigmentation procedure. However, various complications including cold urticaria have been associated with its application. Therefore, the procedure's success depends on the proper case selection, complete isolation of the operating area, and preoperative test for gingival tissue response.

Key points

Why is this case new information?
  • Cold urticaria formation after applying cryosurgery has never been reported in the literature to the best of the authors' knowledge.
What are the keys to the successful management of this case?
  • Preoperative testing for tissue response to cryosurgery will prevent complications like cold urticaria.
What are the primary limitations to success in this case?
  • Improper medical history and not taking tissue response test for cryosurgery.
近年来,由于患者审美需求的增加,牙龈脱色手术得到了广泛的普及。在各种脱色方法中,冷冻手术是一种成本低廉且直接的方法。本病例报告讨论了与四氟乙烷(TFE)冷冻手术脱色方法相关的罕见并发症。病例介绍一个27岁的全身健康男性患者报告了与牙龈黑色素色素沉着有关的审美问题的投诉。上颌第一象限计划采用TFE冷冻手术。患者在手术过程中暴露于TFE冷冻剂后立即出现血管性水肿。考虑为冷性荨麻疹,给患者开了一周的非镇静性抗组胺药。一个月的随访显示牙龈完全愈合和脱色,没有任何衰退或附着丧失。结论TFE冷冻脱色是一种有效的脱色方法。然而,包括冷性荨麻疹在内的各种并发症与它的应用有关。因此,手术的成功取决于正确的病例选择,手术区域的完全隔离,以及术前牙龈组织反应的测试。为什么这个案例是新信息?据作者所知,应用冷冻手术后形成的冷性荨麻疹从未在文献中报道过。成功处理此案的关键是什么?术前检查组织对冷冻手术的反应可以预防诸如寒冷性荨麻疹之类的并发症。在这种情况下,成功的主要限制是什么?病史不正确,冷冻手术未做组织反应试验。
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引用次数: 0
Application of biologics for ridge preservation/reconstruction after implant removal 生物制剂在种植体移除后牙脊保存/重建中的应用
IF 0.7 Q3 Medicine Pub Date : 2022-07-22 DOI: 10.1002/cap.10218
Alberto Monje, Fernando Suárez-López del Amo

Background

The purpose of this review was aimed at providing the rationale supported with a series of cases to apply biologics to enhance orchestrating the healing process at implant removal sites.

Summary

Implant removal is commonly applied on a daily basis, in particular, in cases that exhibit esthetic failures linked to inadequate implant position or in cases of advanced peri-implantitis. Implant removal sites differ substantially from tooth extraction sockets. Implants are ankylosed within the alveolar bone, which therefore have neither mechanoreception nor the elasticity provided by periodontal ligament fibers. As a result, the bone-to-implant contact must be disrupted by means of using a reverse-torque device to minimize trauma. It is possible that the surrounding bone provides limited vascularity, which may interfere with the healing and bone forming process within the socket. Therefore, the use of biologics may enhance this healing and accelerate bone formation in sites where implants are removed due to hopeless functional or esthetic prognoses.

Conclusion

The use of biologics, in particular autologous blood-derived products, may enhance and boost the healing process to potentiate bone availability at a later stage during implant placement.

背景:本综述的目的是通过一系列的案例,为应用生物制剂来促进种植体移除部位的愈合过程提供理论依据。种植体移除通常是日常应用的基础,特别是在表现出与种植体位置不适当相关的美学失败或晚期种植体周围炎的情况下。种植体移除位置与拔牙槽有很大的不同。种植体在牙槽骨内是固定的,因此既没有机械感受力,也没有牙周韧带纤维提供的弹性。因此,必须通过使用反向扭矩装置来破坏骨与种植体的接触,以尽量减少创伤。可能周围的骨提供有限的血管,这可能会干扰窝内的愈合和骨形成过程。因此,在因功能或美观预后不佳而移除植入物的部位,使用生物制剂可以增强愈合并加速骨形成。结论使用生物制剂,特别是自体血源性产品,可以增强和促进愈合过程,从而增强种植体植入后期的骨可用性。
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引用次数: 0
The application of leukocyte- and platelet-rich fibrin (L-PRF) in maxillary sinus augmentation 富白细胞和血小板纤维蛋白(L-PRF)在上颌窦增强术中的应用
IF 0.7 Q3 Medicine Pub Date : 2022-06-27 DOI: 10.1002/cap.10216
Charles A. Powell, Alicia Casarez-Quintana, Jacob Zellner, Omar Al-Bayati, Kerri Font

Background

Since the introduction of sinus augmentation in the 1970s the procedure has been performed with or without biomaterials. Autologous blood products (ABPs) for use in sinus augmentation was first introduced in the 2000s, to aid potentially in bone and soft tissue healing.

Methods

Three different applications of leukocyte- and platelet-rich fibrin (L-PRF) in maxillary sinus augmentation are presented in this case series. In case 1, L-PRF is used in bilateral sinus augmentation to support placement of implants to support a maxillary hybrid denture. Case 2 highlights the use of L-PRF in a complication associate with Schneiderian membrane elevation. Case 3 provides histology taken at the time of implant placement 6 months following L-PRF/xenograft sinus augmentation.

Results

All cases resulted in the successful placement of dental implants. In case 2, an osseodensification procedure was performed with freeze-dried bone allograft, which provided an approximate 4 mm of additional vertical height for implant placement. Histology from case 3 at 6 months post sinus augmentation demonstrated the presence of new vital bone in contact with the xenograft.

Conclusion

To date, there is only a limited amount of evidence reporting on platelet-rich fibrin (PRF) or L-PRF use in maxillary sinus augmentation. Bone gain from either product has ranged from 3.2 to 11.8 mm, with the percentage of newly formed bone reported in case series as 33% ± 5%. Despite the lack of strong evidence, L-PRF appears to have beneficial effects on bone regeneration when used in sinus augmentation.

背景自20世纪70年代鼻窦隆胸术引入以来,该手术使用或不使用生物材料。自体血液制品(ABPs)用于鼻窦增强是在2000年代首次引入的,它可能有助于骨骼和软组织的愈合。方法介绍了富白细胞和富血小板纤维蛋白(L-PRF)在上颌窦增强术中的三种不同应用。在病例1中,L-PRF用于双侧窦增强,以支持种植体的放置,以支持上颌混合义齿。病例2强调了L-PRF在施耐德膜升高并发症中的应用。病例3提供了L-PRF/异种移植物窦增强术后6个月植入时的组织学。结果所有病例均成功植入种植体。在病例2中,使用冷冻干燥的同种异体骨移植物进行骨密度手术,为种植体的放置提供了大约4毫米的额外垂直高度。病例3在鼻窦增强后6个月的组织学显示在与异种移植物接触的地方存在新的重要骨。迄今为止,只有少量的证据报道富血小板纤维蛋白(PRF)或L-PRF用于上颌窦增强术。两种产品的骨增重范围为3.2至11.8 mm,病例系列中报告的新形成骨百分比为33%±5%。尽管缺乏强有力的证据,但L-PRF在鼻窦增强中似乎对骨再生有有益的影响。
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引用次数: 2
Treatment of gummy smile combining crown lengthening, lip repositioning, and the use of polyester threads 治疗粘笑结合冠延长,嘴唇重新定位,并使用聚酯线
IF 0.7 Q3 Medicine Pub Date : 2022-06-25 DOI: 10.1002/cap.10214
Renata O. R. Horn, Júlio C. Joly

Introduction

The case report presents a new possibility of treatment for a gummy smile in a patient with multiple etiologies, such as altered passive eruption and hypermobility upper lip. At first, crown lengthening was not sufficient to achieve the desired aesthetic result, being necessary its combination with lip repositioning.

Case Presentation

Crown lengthening surgery (CLS) was performed in a 20-year-old woman, with a gingival display of 7.5 mm, having her gingival exposure reduced to 5.5 mm. Because the patient continued unsatisfied after 6 months, a new procedure was adopted. To reduce even more her gingival exposure, lip repositioning technique was performed associated with myotomy and the insertion of polyester threads as a physical barrier to prevent relapse.

Conclusion

The result of the gingival display was reduced to 2.5 mm, removing the condition of a gummy smile after the combination of both techniques: crown lengthening, and lip repositioning.

Key points

Why is this case new information?
  • Association of the technique of lip repositioning and myotomy, the insertion of polyester threads that act as a physical barrier against recurrence.
What are the keys to successful management of this case?
  • Correct etiological diagnosis.
  • Prior application of botulinum toxin.
  • Respect the period of 1 month for the insertion of the polyester thread, helping to preserve the suture (limitation of movement).
What are the primary limitations to success in this case?
  • Make the patient aware not to move the lips with the hands in order to observe the incision.
该病例报告提出了一种新的治疗粘笑的可能性,患者有多种病因,如改变被动爆发和上唇过度活动。起初,冠延长不足以达到预期的美学效果,需要与唇部复位相结合。病例介绍冠延长手术(CLS)是一名20岁的女性,她的牙龈显示为7.5 mm,使她的牙龈暴露减少到5.5 mm。由于患者在6个月后仍不满意,我们采用了新的手术方式。为了进一步减少她的牙龈暴露,我们进行了唇复位技术,同时进行了肌切开术和插入聚酯线作为物理屏障,以防止复发。结论采用冠延长+唇复位两种技术组合后,龈面显示缩小至2.5 mm,消除了粘牙现象。为什么这个案例是新信息?结合唇部复位和肌切开术技术,插入聚酯线作为防止复发的物理屏障。成功管理这个案例的关键是什么?正确的病因诊断。事先应用肉毒杆菌毒素。尊重1个月的聚酯线插入期,有助于保存缝线(限制活动)。在这种情况下,成功的主要限制是什么?让患者注意不要用手移动嘴唇,以便观察切口。
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引用次数: 2
Guided protocol for indirect fabrication of a custom provisional restoration prior to immediate implant surgery in the esthetic zone 在美学区进行即刻种植手术前间接制作定制临时修复体的指导方案。
IF 0.7 Q3 Medicine Pub Date : 2022-06-19 DOI: 10.1002/cap.10215
Sarah M. Vargas, Walter G. Dimalanta, Thomas M. Johnson

Background

Delivery of a high-quality provisional restoration at a maxillary anterior immediate implant site enhances patient-centered outcomes and promotes development of favorable hard and soft tissue architecture. The purpose of this report is to present a protocol relying upon compatible guided surgery and laboratory systems for fabrication of a custom provisional crown prior to immediate implant surgery in the esthetic zone.

Methods and Results

A female patient, aged 33 years, presented to the Army Postgraduate Dental School, Fort Gordon, Georgia, with an unfavorable prognosis for tooth #9. The patient elected extraction with immediate implant placement. Prior to the surgery, we utilized a cone-beam computed tomography volume, stone models, implant planning software, and an implant indexing system to fabricate a custom provisional crown. Following extraction of tooth #9 and immediate implant placement, the provisional crown exhibited excellent fit and finish, requiring virtually no chairside adjustment. We noted minimal change in baseline mucosal contours throughout the healing phase.

Conclusion

The clinical/restorative protocol described in this report assured accurate three-dimensional implant positioning and permitted indirect fabrication of a high-quality custom provisional crown in advance of surgery. The laboratory workflow—which dental technicians/auxiliaries can master—has the potential to shorten surgery, enhance treatment outcomes, and increase patient satisfaction.

Key points

Why is this case new information?
  • This report provides a stepwise workflow guiding indirect fabrication of a custom provisional crown prior to immediate implant placement.
What are the keys to successful management of this case?
  • The described technique requires compatible laboratory and guided surgery systems to assure that the restoration accounts for the three-dimensional position and timing of the implant.
What are the primary limitations to success in this case?
  • Dental technicians/auxiliaries can master this protocol and independently produce high-quality provisional implant restorations under supervision, potentially enhancing practice efficiency. However, prac
背景:在上颌前牙即刻种植部位进行高质量的临时修复,可以提高以患者为中心的治疗效果,促进软硬组织结构的良好发展。本报告的目的是介绍一种方案,该方案依靠兼容的引导手术和技工室系统,在美学区即刻种植手术前制作定制的临时牙冠:佐治亚州戈登堡陆军研究生牙科学校有一名33岁的女性患者,她的9号牙预后不良。患者选择拔牙并立即植入种植体。手术前,我们利用锥形束计算机断层扫描、石头模型、种植规划软件和种植体索引系统制作了定制的临时牙冠。拔除 9 号牙齿并立即植入种植体后,临时牙冠显示出极佳的密合度和光洁度,几乎不需要在椅旁进行调整。我们注意到,在整个愈合阶段,基线粘膜轮廓的变化微乎其微:本报告中描述的临床/修复方案确保了种植体的准确三维定位,并允许在手术前间接制作高质量的定制临时牙冠。牙科技师/辅助人员可以掌握的技工室工作流程有可能缩短手术时间、提高治疗效果并增加患者满意度:为什么本病例是新信息?本报告提供了在即刻种植体植入前间接制作定制临时牙冠的分步工作流程。成功处理该病例的关键是什么?所述技术需要兼容的实验室和引导手术系统,以确保修复体考虑到种植体的三维位置和时间。该病例成功的主要限制因素是什么?牙科技师/辅助人员可以掌握这种方法,并在监督下独立制作高质量的临时种植体修复体,从而提高工作效率。但是,从业者应该对员工进行充分的培训,以优化可靠性和质量。
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引用次数: 2
Treatment of peri-implant soft tissue dehiscence around implants placed in calvarial bone graft maxilla and mandible 20 years ago: A case report 20 年前上颌骨和下颌骨钙骨移植种植体周围软组织开裂的治疗:病例报告。
IF 0.7 Q3 Medicine Pub Date : 2022-06-14 DOI: 10.1002/cap.10213
Martha Watanabe, Rémy Tanimura

Introduction

Despite tissue augmentation and management prior implantation, long-term observation can reveal a change in peri-implant phenotype with some lack of keratinized mucosa (KM). The treatment approach of peri-implant dehiscence in multiple implants is not clearly defined. This report describes the different periodontal surgical approaches undertaken to promote the gingival margin stability and to prevent the peri-implant mucosal inflammation over time.

Case Presentation

A 64-year-old woman with peri-implant tissue dehiscence regarding implants placed 20 years ago in a calvarial bone grafted maxilla and mandible was treated. Right maxillary and mandible peri-implants soft tissue were treated with a large apically positioned partial-thickness flap (APPTF) combined to a free gingival graft (FGG) simultaneously. For the left maxillary, where a frenum was in tension associated with infection and pockets, a large APPTF followed by a FGG 4 months later were performed. The KM width (KMW) increased in three operated sites with a gain average of 2.2 mm. The plaque control record decreased from 68% to 21%. All the probing depths were lower than 3 mm. Bleeding on probing was significantly reduced. The gingival index (GI) went from 1.5 to 0.25.

Conclusion

In a multiple implants soft tissue dehiscence case, an APPTF associate to a FGG, delayed or not, seems to be a safety primary approach to improve the KMW and to stabilize the peri-implants soft tissue. Further, a connective tissue graft in a bilaminar approach could be an option to enhance soft tissue thickness and esthetic outcomes.

Key points

Why is this case new information?
  • To the best of the authors' knowledge, there are very limited studies regarding multi-implant soft tissue dehiscence treatment. Relevant guidelines are not clearly defined.
  • Despite peri-implant hard and soft tissue augmentation, after a long-term observation (20 years of function), we can observe a change in peri-implant soft tissue phenotype (PISTP) with periodontal complication.
What are the keys to successful management of this case?
  • Removal of peri-implant infection and tissue tension (frenum) by a larg
导言:尽管在种植前进行了组织增量和管理,但长期观察会发现种植体周围表型发生变化,部分角化粘膜(KM)缺失。多颗种植体周围开裂的治疗方法尚未明确定义。本报告介绍了不同的牙周手术方法,以促进龈缘的稳定,防止种植体周围粘膜炎症的长期存在:一名 64 岁的女性,20 年前在上颌骨和下颌骨钙骨移植的种植体上出现种植体周围组织开裂,接受了治疗。右侧上颌骨和下颌骨种植体周围软组织采用大型根尖定位部分厚度皮瓣(APPTF)结合游离牙龈移植(FGG)同时治疗。在左上颌,由于龈缘紧张并伴有感染和龈袋,因此在 4 个月后进行了大型 APPTF 和 FGG 治疗。三个手术部位的 KM 宽度(KMW)平均增加了 2.2 毫米。牙菌斑控制记录从 68% 降至 21%。所有的探诊深度都低于 3 毫米。探诊出血明显减少。牙龈指数(GI)从 1.5 降至 0.25:在多颗种植体软组织开裂的病例中,APPTF 与 FGG(无论是否延迟)似乎是一种安全的主要方法,可以改善 KMW 并稳定种植体周围的软组织。此外,双层法中的结缔组织移植也是一种选择,可增加软组织厚度和美学效果:为什么本病例是新信息?据作者所知,关于多种植体软组织开裂治疗的研究非常有限。相关指南也没有明确定义。尽管进行了种植体周围软硬组织增量,但经过长期观察(20 年的功能),我们可以发现种植体周围软组织表型(PISTP)会随着牙周并发症的发生而发生变化。成功处理这一病例的关键是什么?在软组织增量手术前,先用一个大的根尖定位部分厚度皮瓣(APPTF)去除种植体周围感染和组织张力(龈沟)。如果种植体周围软组织非常薄,则需要小心保护骨膜上神经丛的血液供应。应移植大面积的 APPTF 和足量的角化粘膜 (KM),以弥补组织的萎缩。此病例成功的主要限制因素是什么?美观要求高。有必要采用结缔组织移植(CTG)的二次双层方法来改善美学效果。患者的依从性。
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引用次数: 0
PDGF-BB-enriched collagen matrix to treat multiple gingival recessions with the tunneled coronally advanced flap 富含pdgf - bb的胶原基质在冠状进展隧道皮瓣治疗多发性牙龈衰退中的应用
IF 0.7 Q3 Medicine Pub Date : 2022-06-04 DOI: 10.1002/cap.10211
Shayan Barootchi, William V. Giannobile, Lorenzo Tavelli

Background

With technological advancements in reconstructive periodontology, traditional protocols for the treatment of gingival recessions (GRs) can be challenged. This manuscript presents preliminary findings of a novel minimally-invasive approach for the regenerative treatment of multiple adjacent GR defects.

Methods

Two healthy adults were treated as part of this study. Multiple adjacent GRs in both subjects (1 in the mandible, and 1 in the maxilla) were treated employing a tunneled coronally advanced flap (TCAF) design, with the application of a cross-linked collagen matrix (CCM) that was enriched with recombinant human platelet-derived growth factor-BB (PDGF-BB) that was also applied on the prepared root surfaces. Clinical, ultrasonographic, esthetic, and patient-reported outcomes were observed at approximately 6- and 18-month time points.

Results

All sites healed uneventfully after the treatments. Complete root coverage was achieved and maintained throughout the follow-up observations, from 6 to 18 months. Patients reported minimal discomfort and reduction of dentinal hypersensitivity at the augmented sites. The areas augmented with CCM + PDGF-BB revealed an increased soft tissue thickness relative to baseline (pretreatment) measures, as well as reduction in the level of the facial bone dehiscences.

Conclusion

This article describes the success of two cases of a novel minimally invasive regenerative approach for the treatment of multiple adjacent GR defects by the TCAF, using a CCM loaded with PDGF-BB. This approach offers potential as a minimally-invasive method to repair multiple adjacent GRs.

背景随着牙周病重建技术的进步,传统的牙龈衰退治疗方案受到了挑战。这篇手稿提出了一种新的微创方法再生治疗多个相邻的GR缺陷的初步发现。方法选取两名健康成人作为研究对象。两名受试者(下颌骨1例,上颌1例)的多个相邻GRs采用隧道冠状推进皮瓣(TCAF)设计治疗,并应用交联胶原基质(CCM),该基质富含重组人血小板衍生生长因子- bb (PDGF-BB),也应用于制备的根表面。在大约6个月和18个月的时间点观察临床、超声、美学和患者报告的结果。结果所有部位经治疗后均痊愈。在6至18个月的随访观察中,实现并保持了完全的根覆盖。患者报告在增强部位的不适和牙本质过敏减少最小。CCM + PDGF-BB增强的区域显示,相对于基线(预处理)测量,软组织厚度增加,面部骨开裂水平降低。本文描述了两例新型微创再生方法的成功,该方法使用装载PDGF-BB的CCM,通过TCAF治疗多个相邻GR缺陷。该方法作为一种微创修复多发相邻GRs的潜在方法。
{"title":"PDGF-BB-enriched collagen matrix to treat multiple gingival recessions with the tunneled coronally advanced flap","authors":"Shayan Barootchi,&nbsp;William V. Giannobile,&nbsp;Lorenzo Tavelli","doi":"10.1002/cap.10211","DOIUrl":"10.1002/cap.10211","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>With technological advancements in reconstructive periodontology, traditional protocols for the treatment of gingival recessions (GRs) can be challenged. This manuscript presents preliminary findings of a novel minimally-invasive approach for the regenerative treatment of multiple adjacent GR defects.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Two healthy adults were treated as part of this study. Multiple adjacent GRs in both subjects (1 in the mandible, and 1 in the maxilla) were treated employing a tunneled coronally advanced flap (TCAF) design, with the application of a cross-linked collagen matrix (CCM) that was enriched with recombinant human platelet-derived growth factor-BB (PDGF-BB) that was also applied on the prepared root surfaces. Clinical, ultrasonographic, esthetic, and patient-reported outcomes were observed at approximately 6- and 18-month time points.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>All sites healed uneventfully after the treatments. Complete root coverage was achieved and maintained throughout the follow-up observations, from 6 to 18 months. Patients reported minimal discomfort and reduction of dentinal hypersensitivity at the augmented sites. The areas augmented with CCM + PDGF-BB revealed an increased soft tissue thickness relative to baseline (pretreatment) measures, as well as reduction in the level of the facial bone dehiscences.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This article describes the success of two cases of a novel minimally invasive regenerative approach for the treatment of multiple adjacent GR defects by the TCAF, using a CCM loaded with PDGF-BB. This approach offers potential as a minimally-invasive method to repair multiple adjacent GRs.</p>\u0000 </section>\u0000 </div>","PeriodicalId":55950,"journal":{"name":"Clinical Advances in Periodontics","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://aap.onlinelibrary.wiley.com/doi/epdf/10.1002/cap.10211","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10637069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
期刊
Clinical Advances in Periodontics
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