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Analysis of thrombosis risk of commissural misaligned transcatheter aortic valve prostheses using particle image velocimetry 颗粒图像测速法分析关节错位经导管主动脉瓣假体血栓形成风险
IF 1 4区 工程技术 Q3 Engineering Pub Date : 2023-02-28 DOI: 10.1515/teme-2022-0100
F. Borowski, S. Kaule, Jan Oldenburg, K. Schmitz, A. Öner, M. Stiehm
Abstract Due to excellent clinical results, transcatheter aortic valve replacement (TAVR) has evolved to a treatment option for patients with low surgical risk, resulting in an increasing demand for durable heart valve prostheses. Durability of TAVR could be limited by leaflet thrombosis. Thrombus formation in the aortic root is mainly affected by the hemodynamic situation, which is dependent on the positioning of the implant. We investigated the flow field in the aortic root after TAVR implantation by means of particle image velocimetry. To quantify the influence of the implant-position with respect to an alignment or misalignment of the leaflet commissures on the thrombogenic potential, we used a transport equation for residence time (RT) to consider washout behavior. Furthermore, we introduced a shear effect criterion (SIE) to address platelet activation as a measure for a potential thrombus formation. Misaligned implantation of a TAVR resulted in a reversed direction of rotation of the occurring recirculation area. This led to fluid flow with comparable areas of increased relative blood RT (RTaligned: 97.6%, RTmisaligned: 88.0%) and a smaller area of low shear load for the misaligned TAVR (SIEaligned: 57.7%, SIEmisaligned: 3.70%) into the sinus region, indicating a higher potential for thrombus formation.
由于出色的临床效果,经导管主动脉瓣置换术(TAVR)已发展成为低手术风险患者的治疗选择,导致对耐用心脏瓣膜假体的需求不断增加。TAVR的持久性可能受到小叶血栓形成的限制。主动脉根部血栓的形成主要受血流动力学状况的影响,而血流动力学状况又依赖于植入物的位置。我们用粒子图像测速法研究了TAVR植入术后主动脉根部的流场。为了量化植入位置对小叶相交对齐或不对齐对血栓形成潜力的影响,我们使用了停留时间(RT)的传递方程来考虑冲洗行为。此外,我们引入了剪切效应标准(SIE)来解决血小板活化作为潜在血栓形成的措施。错位植入TAVR导致发生再循环区的旋转方向相反。这导致相对血液RT增加的区域(rtalaligned: 97.6%, RTmisaligned: 88.0%)和错位TAVR的低剪切负荷面积更小(SIEaligned: 57.7%, siemaligned: 3.70%)的流体流入窦区,表明血栓形成的可能性更高。
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引用次数: 2
Vereinfachtes Verfahren zur Ermittlung von Messunsicherheiten zur Bestimmung der Messprozesseignung industrieller Prüfprozesse 对于工业审计进程就得出衡量不确定性问题的简化程序
IF 1 4区 工程技术 Q3 Engineering Pub Date : 2023-02-22 DOI: 10.1515/teme-2022-0004
Ernst Wiedenmann, T. Schlüter
Zusammenfassung Aufgrund der Erfahrung in vielen Begutachtungen und Seminaren zur Berechnung von Messunsicherheiten, fällt es z.T. selbst ISO/IEC 17025 akkreditierten Prüf- und Kalibrierlaboratorien schwer, angemessene Messunsicherheiten zu berechnen. Hier soll deshalb erstmalig ein neues, vereinfachtes Verfahren zur Berechnung von Messunsicherheiten für industrielle Prüfprozesse vorgestellt werden. Neu daran ist, dass es ausschließlich auf der Berücksichtigung der Messsystemspezifikation (Gerätespezifikationen) und der erweiterten Vergleichpräzision (Präzision mit erweiterten Vergleichbedingungen) basiert. Dadurch wird es in der industriellen Praxis wesentlich einfacher Messunsicherheiten für Prüfprozesseignungen zu ermitteln, da Gerätespezifikationen in vielen Fällen vorliegen und die Bestimmung der erweiterten Vergleichpräzision bereits zum Werkzeug vieler Anwender gehört. Das Verfahren ist nicht für Kalibrierverfahren und die damit verbundenen Rückführungen geeignet. Im Rahmen von Konformitätsaussagen der industriellen Prüfprozesse kann es verwendet werden.
这种对英国人和英国人的影响这就意味着我们将第一次提出一个新的简单化的方法来计算工业审计进程的不确定性。新发现的是,这一方针完全基于在设备更换上的测量系统规格和在可比条件下的精准度。这一简单多了,因为在许多情况下都有设备的更换手段,并且提高精度已经成为许多用户可用手段的一部分。相关程序不适合校准程序或引用。在遵守工业审计过程的框架中可以利用这个词。
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引用次数: 0
Automated end-of-line quality assurance with visual inspection and convolutional neural networks 采用视觉检查和卷积神经网络的自动线末质量保证
IF 1 4区 工程技术 Q3 Engineering Pub Date : 2023-02-17 DOI: 10.1515/teme-2022-0092
Hang-Young Kim, A. Frommknecht, Bernd Bieberstein, J. Stahl, Marco F. Huber
Abstract End-of-line (EOL) quality assurance of finished components has so far required additional manual inspections and burdened manufacturers with high labor costs. To automate the EOL process, in this paper a fully AI-based quality classification system is introduced. The components are automatically placed under the optical inspection system employing a robot. A Convolutional Neural Network (CNN) is used for the quality classification of the recorded images. After quality control, the component is sorted automatically in different bins depending on the quality control result. The trained CNN models achieve up to 98.7% accuracy on the test data. The classification performance of the CNN is compared with that of a rule-based approach. Additionally, the trained classification model is interpreted by an explainable AI method to make it comprehensible for humans and reassure them about its trustworthiness. This work originated from an actual industrial use case from Witzenmann GmbH. Together with the company, a demonstrator was realized.
到目前为止,成品部件的质量保证需要额外的人工检查,给制造商带来了高昂的人工成本。为了实现EOL过程的自动化,本文介绍了一个完全基于人工智能的质量分类系统。这些部件被自动放置在采用机器人的光学检测系统下。使用卷积神经网络(CNN)对记录的图像进行质量分类。质量控制完成后,根据质量控制结果自动分选到不同的料仓中。训练后的CNN模型在测试数据上达到了98.7%的准确率。将CNN的分类性能与基于规则的方法进行了比较。此外,经过训练的分类模型通过可解释的人工智能方法进行解释,使其易于理解,并向人们保证其可靠性。这项工作源自于Witzenmann GmbH的一个实际工业用例。与公司一起,实现了一个示范。
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引用次数: 0
Explainable AI for sensor-based sorting systems 基于传感器的分类系统的可解释人工智能
IF 1 4区 工程技术 Q3 Engineering Pub Date : 2023-02-17 DOI: 10.1515/teme-2022-0097
Mathias Anneken, M. Veerappa, Marco F. Huber, C. Kühnert, Felix Kronenwett, Georg Maier
Abstract Explainable artificial intelligence (XAI) can make machine learning based systems more transparent. This additional transparency can enable the use of machine learning in many different domains. In our work, we show how XAI methods can be applied to an autoencoder for anomaly detection in a sensor-based sorting system. The setup of the sorting system consists of a vibrating feeder, a conveyor belt, a line-scan camera and an array of fast-switching pneumatic valves. It allows the separation of a material stream into two fractions, realizing a binary sorting task. The autoencoder tries to mimic the normal behavior of the nozzle array and thus can detect abnormal behavior. The XAI methods are used to explain the output of the autoencoder. As XAI methods global and local approaches are used, which means we receive explanations for both a single result and the whole autoencoder. Initial results for both approaches are shown, together with possible interpretations of these results.
可解释人工智能(XAI)可以使基于机器学习的系统更加透明。这种额外的透明度可以使机器学习在许多不同领域的使用成为可能。在我们的工作中,我们展示了如何将XAI方法应用于基于传感器的分类系统中的自动编码器中进行异常检测。分拣系统的设置由振动给料机、传送带、线扫描相机和一组快速切换的气动阀组成。它允许将物料流分成两个部分,实现二元分选任务。自动编码器试图模仿喷嘴阵列的正常行为,从而可以检测异常行为。XAI方法用于解释自编码器的输出。由于XAI方法使用了全局方法和局部方法,这意味着我们可以收到单个结果和整个自编码器的解释。本文展示了两种方法的初步结果,以及对这些结果的可能解释。
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引用次数: 0
Elektrische Levitationsdetektion für die Verwendung im Tissue Engineering 构造工程使用电子莱维探测器
IF 1 4区 工程技术 Q3 Engineering Pub Date : 2023-02-17 DOI: 10.1515/teme-2022-0099
Stefan Scheunemann, C. Pientschke, U. Zabarylo, Kay Raum
Zusammenfassung Die Züchtung und Gestaltung biologischen Gewebes im Labor (Tissue Engineering) verspricht breite medizinische Anwendung. Die notwendige Strukturierung der künstlichen Gewebe kann mittels stehender Ultraschallwellen durch Levitation erfolgen. In diesem Beitrag wird eine Methode zur elektrischen Detektion der Levitation und Experimente zu ihrer Verifizierung vorgestellt. Die Ultraschallwellen werden mit piezoelektrischen Wandlern erzeugt. Die Kontrolle der Levitation beruht auf der Auswertung der Sendespannung. Optische Aufnahmen levitierter Kunststoffpartikel erlaubten die frequenzabhängige Ermittlung der Levitationsebenenabstände und eine Korrelation zu den Sendespannungen. Es zeigte sich, dass die Levitationsbedingung über einen relativ breiten Frequenzbereich erfüllt ist. Durch Berücksichtigung der frequenzabhängigen Sendeleistung kann mittels einer normierten Kurve ein gleichmäßiger Schalldruck über den gesamten für die Levitation relevanten Frequenzbereich eingestellt werden. Die gewonnenen Ergebnisse fließen in die Entwicklung eines Gerätes ein, mit dem parallel mehrere Proben für das Tissue Engineering per Levitation gezielt strukturiert werden können. Die Proben werden dabei nutzerfreundlich in Silikon- oder Teflon-Kammern prozessiert, indem ein Ultraschallsender und eine Reflektorplatte verwendet werden. Damit können Versuchsreihen zum Tissue-Engineering effizienter als bisher durchgeführt werden.
概括在实验室生物组织的繁殖和设计,成为广泛的医学目标。组织结构的组织结构可以利用悬空作用。文章提供了测利亚达和证实其封口的方法。声波是由发光的传感器引起的。悬念控制依赖于释放电压。使用利未空间塑料粒子让人们能够找到乐谱间距并找到与运输紧张关系的相关性。结果,临界值达到了较低的波幅。根据与频率相关的范围,制定了一个标准曲线以确定有效载荷。研究结果将这些结果引入到一种可以同时对多个“叠加”的组织工程样本进行设计的仪器中。这样一来,样本就可以方便用户使用,即使用超声波发射器和反射板,对硅胶或特氟隆室进行循环。这将提高组织工程的效果。
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引用次数: 0
Measurement systems and sensors with cognitive features II 具有认知特征的测量系统与传感器2
IF 1 4区 工程技术 Q3 Engineering Pub Date : 2023-02-15 DOI: 10.1515/teme-2023-0004
K. Sommer, M. Heizmann, A. Schütze
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引用次数: 0
The SCALEX facility – an apparatus for scaled fluid dynamical experiments SCALEX设备-一种用于规模流体动力学实验的设备
IF 1 4区 工程技术 Q3 Engineering Pub Date : 2023-02-10 DOI: 10.1515/teme-2022-0121
M. Sharifi Ghazijahani, C. Kästner, V. Valori, A. Thieme, K. Täschner, J. Schumacher, C. Cierpka
Abstract The working conditions of the Scaled Convective Airflow Laboratory Experiment (SCALEX) at Technische Universität Ilmenau and sample experiments are reported. The SCALEX facility is a pressure vessel which allows for downscaling of laboratory experiments up to a factor of 20 by compression of gaseous working fluids, air or sulfur hexafluoride, to change the material properties of the fluid. The requirements and conditions for downscaling of fluid dynamical problems are discussed in detail. Long-term high and low pressure tests are conducted to screen the stability of the experimental environment inside the vessel against pressure and temperature fluctuations. Finally, a Rayleigh–Bénard convection experiment at an aspect ratio 10 is performed inside the SCALEX facility as a proof of concept. The reference experiment was conducted under 4.5 bar pressure for Ra = 1.9 × 105. However, the Rayleigh number could be varied in a wide range of Ra = 104 … 108. The flow investigation was pursued with stereoscopic particle image velocimetry in horizontal mid-plane through the convection cell. To improve the image quality the cameras were placed inside the pressure cell and tested up to 6 bar. Thus the feasibility of optical flow measurements at elevated pressures is shown.
摘要:本文报道了Universität Ilmenau Technische的尺度对流气流实验室实验(SCALEX)的工作条件和样品实验。SCALEX设备是一种压力容器,通过压缩气态工作流体、空气或六氟化硫来改变流体的材料特性,可以将实验室实验的规模缩小到原来的20倍。详细讨论了流体动力学问题降尺度的要求和条件。进行长期的高、低压试验,以筛选容器内实验环境对压力和温度波动的稳定性。最后,在SCALEX设备内进行了宽高比为10的rayleigh - bassanard对流实验,作为概念验证。参考实验在4.5 bar压力下进行,Ra = 1.9 × 105。然而,瑞利数可以在Ra = 104…108的大范围内变化。采用立体粒子图像测速法在水平中层通过对流池进行流动研究。为了提高图像质量,相机被放置在压力箱内,并测试了高达6巴的压力。从而表明了在高压条件下进行光流测量的可行性。
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引用次数: 2
Kontaktlose induktive Strömungstomografie in grundlegender und angewandter Fluiddynamik 基本动力学的惯性插曲
IF 1 4区 工程技术 Q3 Engineering Pub Date : 2023-02-10 DOI: 10.1515/teme-2022-0103
Max Sieger, Rahul Mitra, Ivan Glavinic, Matthias Ratajczak, S. Sonntag, Thomas Gundrum, F. Stefani, Thomas Wondrak, S. Eckert
Kurzfassung Mit der kontaktlosen induktiven Strömungstomografie (CIFT) lassen sich Geschwindigkeitsfelder in elektrisch leitfähigen Flüssigkeiten global bestimmen. Kenntnisse über den Strömungszustand in Metallschmelzen sind für industrielle Prozesse, wie das Stranggießen von Stahl, von immenser Bedeutung und können auch in der Grundlagenforschung nutzbringend angewendet werden, z.B. zur Analyse von konvektiven Flüssigmetallströmungen als Modellsysteme des Wärmetransportes. Das Verfahren beruht auf der präzisen Messung kleinster Magnetfeldänderungen durch geeignete Sonden und der nachfolgenden Rekonstruktion der Strömungsstruktur durch die Lösung eines linearen inversen Problems. In dieser Veröffentlichung geben wir einen Überblick über die Entwicklungen der letzten Dekade und diskutierten je einen Anwendungsfall für CIFT aus der grundlegenden und der angewandten Fluiddynamik.
将数据简化为导频闪图形(CIFT),可以将数据回路转换为全插电液。对岩溶水沸腾状态的了解对于工业过程,如钢互溶水,有着巨大的影响,并且可以在基础研究中有效运用,例如,分析液态金属流作为一个热运输模型。这个方法依赖于通过适当探针对微小磁场变化的精确测量。并与此相关的设计设计来解决线性内问题。在本报告中,我们对过去十年的发展情况做了总结,并讨论了其中一个用于tift的基本和可用流动力。
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引用次数: 1
Perspectives on AI-driven systems for multiple sensor data fusion 多传感器数据融合的人工智能驱动系统展望
IF 1 4区 工程技术 Q3 Engineering Pub Date : 2023-02-09 DOI: 10.1515/teme-2022-0094
W. Koch
Abstract Artificially intelligent automation has not only impact on sensor technologies, but also on comprehensive multiple sensor systems for assisting situational awareness and decision-making. This is particularly true for integrated Manned-unManned-Teaming (MuM-T), for example. From a systems engineering perspective which does not exclude applications in the defence domain, three tasks need to be fulfilled: (1) Design artificially intelligent automation in a way that human beings are mentally and emotionally able to master each situation. (2) Identify technical design principles to facilitate the responsible use of AI in ethically critical applications. (3) Guarantee that human decision makers always have full superiority of information, decision-making, and options of action. Our discussion of AI-driven systems for multiple sensor data fusion results in recommendations and key results. We are addressing the algorithms needed, the data to be processed, the programming skills required, the computing devices to be used, the inevitable anthropocentric design, the reviewing of R & D efforts necessary, and the integration of different dimensions in a systems-of-systems point of view.
人工智能自动化不仅对传感器技术产生影响,而且对辅助态势感知和决策的综合多传感器系统产生影响。例如,对于集成的有人-无人-组队(MuM-T)来说尤其如此。从不排除国防领域应用的系统工程角度来看,需要完成三个任务:(1)设计人工智能自动化,使人类在精神上和情感上能够掌握每种情况。(2)确定技术设计原则,以促进在道德关键应用中负责任地使用人工智能。(3)保证人类决策者始终具有充分的信息优势、决策优势和行动选择优势。我们对人工智能驱动的多传感器数据融合系统的讨论产生了建议和关键结果。我们正在处理所需的算法、需要处理的数据、所需的编程技能、要使用的计算设备、不可避免的以人类为中心的设计、对必要的研发工作的审查,以及从系统的角度对不同维度的整合。
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引用次数: 1
Analysis of the phase-dependent fluorescence decay time of treated wood using FD-FLIM 用FD-FLIM分析处理木材的相依赖荧光衰减时间
IF 1 4区 工程技术 Q3 Engineering Pub Date : 2023-02-02 DOI: 10.1515/teme-2022-0114
N. Leiter, M. Wohlschläger, M. Versen
Abstract For sustainable handling of wood and high material utilization, post-consumer wood has to be sorted by post-consumer wood categories in Germany. The non-destructive FD-FLIM method could improve the wood recycling process by automatic classification of waste wood into post-consumer wood classes. Thus, the phase-dependent fluorescence decay time of treated wood is analysed in this study to obtain the impact of the treatment on the fluorescence decay time. It is shown that treated and untreated wood can be differentiated using the fluorescence decay time, although the state-of-the-art theoretical fluorescence decay time differs from the experimentally determined fluorescence decay time.
为了可持续处理木材和高材料利用率,在德国,消费后木材必须按消费后木材类别进行分类。无损FD-FLIM方法可以通过将废木材自动分类为消费后的木材类别来改善木材回收过程。因此,本研究分析了处理木材的相位依赖荧光衰减时间,以获得处理对荧光衰减时间的影响。研究表明,处理和未经处理的木材可以区分使用荧光衰减时间,虽然最先进的理论荧光衰减时间不同于实验确定的荧光衰减时间。
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引用次数: 0
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Tm-Technisches Messen
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