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Factors affecting the unused short peripheral catheters: A neverending debate? A cross-sectional study in hospitalized patients. 影响未使用外周短导管的因素:无休止的争论?住院患者的横断面研究。
IF 1.6 3区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-12-09 DOI: 10.1177/11297298241303200
Federica Canzan, Jessica Longhini, Elisabetta Allegrini, Giulia Marini, Elisabetta Mezzalira, Giorgia Zulianello, Elisa Ambrosi

Background: Concern about unused vascular access devices has increased, but data on idle short peripherally intravascular catheters in medical-surgical units is still scarce. We aimed to assess the prevalence of unused short peripheral catheters in hospitalized patients and identify risk factors and reasons that lead nurses to maintain them in situ.

Methods: A cross-sectional observational study was performed in September 2022. Clinical observation (24h) and medical records review were assessed to collect patient demographics and catheter-related information. Nurses were asked the main reason for continuing the use of the unused catheter. The primary outcome was the prevalence of unused short peripheral catheters, which were no longer used for intravenous fluids or medications in the previous 24 h. Multivariate logistic regression has been performed to evaluate risk factors for unused catheters. The STROBE checklist was used to report our study.

Results: Seven hundred and sixty-four patients were included; out of the 621 patients with at least one short peripheral catheter, one-third had at least one unused catheter. The risk of having an unused peripherally intravascular catheter was almost double when the catheter was positioned in the emergency department. Catheters of smaller calibers and in situ for fewer days were less likely to be unused. The main reasons for keeping a peripherally intravascular catheter unused in situ were clinical conditions.

Conclusion: Unused short peripheral catheters are still quite frequent. While specific clinical needs justified some unused short peripheral catheters, a proportion remained unexplained and potentially avoidable. Nurses and policymakers can use the findings to inform decision-making and protocols to manage peripherally inserted catheters to reduce unused short peripheral catheters and, consequently, complications and costs and improve patient safety and quality of care.

背景:对未使用的血管通路装置的关注有所增加,但在内科外科单位闲置的短周血管内导管的数据仍然很少。我们的目的是评估住院患者未使用的短外周导管的患病率,并确定导致护士将其保留在原位的危险因素和原因。方法:于2022年9月进行横断面观察性研究。评估临床观察(24h)和病历回顾,收集患者人口统计学和导管相关信息。护士被问及继续使用未使用导管的主要原因。主要结果是未使用的短外周导管的患病率,这些导管在过去24小时内不再用于静脉输液或药物治疗。使用多变量逻辑回归来评估未使用导管的危险因素。使用STROBE检查表报告我们的研究。结果:共纳入764例患者;在621例至少有一根短外周导管的患者中,三分之一的患者至少有一根未使用的导管。当导管放置在急诊科时,未使用的外周血管内导管的风险几乎是两倍。较小口径的导管在原位放置的时间较短,不太可能被使用。保留外周血管内导管原位未使用的主要原因是临床条件。结论:外周短导管未使用的情况仍然较多。虽然特定的临床需要证明一些未使用的短外周导管是合理的,但仍有一部分未解释,可能是可以避免的。护士和决策者可以利用这些发现为决策和方案提供信息,以管理外周置管,减少未使用的短外周置管,从而减少并发症和成本,并提高患者安全和护理质量。
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引用次数: 0
Effect of different sealing caps on the backflow of short-term dialysis catheters: A bench study. 不同密封帽对短期透析导管回流影响的实验研究。
IF 1.6 3区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-12-06 DOI: 10.1177/11297298241301508
Daniele Privitera, Davide Giustivi, Thomas Langer, Elisabetta Fiorina, Federica Gotti, Michela Rossini, Beatrice Brunoni, Nicolò Capsoni, Alberto Dal Molin, Francesco Zadek

Background: Needle-free connectors (NFCs) are recommended as closure systems for peripheral and central vascular catheters to reduce needlestick injuries and infections, while potentially reducing blood reflux. However, their performance in short-term dialysis catheters has never been evaluated. The aim of this study was to evaluate the backflow associated with two NFCs (Neutron™ and Tego™) compared to the standard closure.

Methods: In this bench study, the physiological blood pressure of the superior vena cava was simulated. Expert operators performed three sealing sequences for each combination of connector and lumens of the catheter, with and without closing the clamp. After that, the backflow was measured in millimeters using a high-precision digital caliper.

Results: No combination of caps, lumens, or clamping sequences eliminated the backflow. No differences were observed between standard caps and NFCs in both lumens, apart from the Tego™/No clamp combination in the proximal lumen that showed higher backflow (standard cap 15 [11; 17] mm vs Tego™ 23 [19; 25] mm, p < 0.001). Clamping reduced backflow in both the proximal (13 [11; 17] mm vs 20 [13; 25] mm) and distal lumens (12 [11; 16] mm vs 14 [12; 17] mm). No differences were found between standard caps and NFCs in the distal lumen, regardless of clamping. Proximal lumen consistently exhibited larger backflow (14 [12; 22] mm) compared to distal lumens (13 [11; 17] mm, p = 0.005).

Conclusion: NFCs do not seem to introduce any advantage on backflow reduction as compared to a standard cap combined with lumen and clamping. Our data suggest that clamping should become standard practice when NFCs are used in the management of short-term dialysis catheters.

背景:无针连接器(nfc)被推荐作为外周和中央血管导管的闭合系统,以减少针刺损伤和感染,同时潜在地减少血液反流。然而,它们在短期透析导管中的表现从未被评估过。本研究的目的是评估两种nfc (Neutron™和Tego™)与标准闭包相关的回流情况。方法:采用模拟上腔静脉生理血压的实验方法。专家操作人员对导管接头和管腔的每种组合执行了三次密封顺序,有和没有关闭夹钳。之后,用高精度数字卡尺以毫米为单位测量回流。结果:帽、管腔或夹紧序列的组合均不能消除回流。在两个管腔中,除了近端管腔的Tego™/No钳组合显示更高的回流外,标准帽和nfc之间没有差异(标准帽15 [11;17] mm vs Tego™23 [19;25] mm, p p = 0.005)。结论:与结合管腔和夹紧的标准帽相比,nfc在减少回流方面似乎没有任何优势。我们的数据表明,当nfc用于短期透析导管的管理时,夹紧应成为标准做法。
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引用次数: 0
Distal radial artery palpability and successful arterial access for coronary angiography: A post-hoc analysis from two randomized trials. 桡动脉远端可触及性和冠状动脉造影成功的动脉通路:来自两个随机试验的事后分析。
IF 1.6 3区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-12-06 DOI: 10.1177/11297298241296570
Anastasios Apostolos, Amalia Papanikolaou, Angeliki Papageorgiou, Athanasios Moulias, Georgios Vasilagkos, Konstantinos Pappelis, Adel Aminian, Gregory A Sgueglia, Juan F Iglesias, Periklis Davlouros, Grigorios Tsigkas

Background: Distal radial artery access (DRA) has been emerged as an alternative for conventional transradial arterial access. While palpation of radial artery is mandatory prior coronary angiography, it remains unknown the clinical impact of palpation in DRA success. Aim of our study is to explore whether the palpability of distal radial artery is linked with higher rates of successful arterial access.

Methods: We conducted a post-hoc analysis using data from two randomized-controlled trials on DRA. All patients with available data on distal radial artery palpability and cannulation's success were included in our analysis. No procedure was performed with ultrasound guidance.

Results: Data on the palpability of the distal radial artery and the DRA success were available for 435 patients. Successful distal radial artery cannulation was attempted in 255 and 98 of patients with and without palpable distal radial artery, respectively. No significant difference between the two groups was observed (81.5% vs 80.3%, p = 0.786). Univariate analysis revealed statistically significant difference in gender, height, known CAD, valvular disease as indication for angiography and number of skin punctures. Multivariate analysis included these variables, as well as palpability of the distal radial artery and found that number of skin punctures and valvular disease as indication are significantly associated with DRA success.

Conclusion: According our post-hoc analysis, the palpability of the distal radial artery is not associated with higher rates of DRA success. Further studies are required for the validation of these results.

背景:桡动脉远端通路(DRA)已成为传统经桡动脉通路的替代方法。虽然在冠状动脉造影之前必须触诊桡动脉,但触诊对DRA成功的临床影响尚不清楚。我们研究的目的是探讨桡动脉远端可触及性是否与较高的成功动脉通路率有关。方法:我们使用两项DRA随机对照试验的数据进行事后分析。所有具有桡动脉远端可触及性和插管成功数据的患者都被纳入我们的分析。在超声引导下不进行任何手术。结果:435例患者桡动脉远端可触及性和DRA成功的数据。桡动脉远端可触及患者255例,桡动脉远端可触及患者98例,桡动脉远端可触及患者98例。两组间差异无统计学意义(81.5% vs 80.3%, p = 0.786)。单因素分析显示,性别、身高、已知CAD、血管造影指征瓣膜疾病和皮肤穿刺次数有统计学意义。多变量分析包括这些变量,以及桡动脉远端触感,发现皮肤穿刺次数和瓣膜疾病作为指征与DRA成功显著相关。结论:根据我们的事后分析,桡动脉远端可触及性与DRA成功率无关。需要进一步的研究来验证这些结果。
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引用次数: 0
A prospective, observational study of a pediatric affect and cooperation scale (HRAD±) for vascular access procedures. 一项关于儿童对血管通路手术的影响和合作量表(HRAD±)的前瞻性观察研究。
IF 1.6 3区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-12-05 DOI: 10.1177/11297298241302897
Romy Yun, Kristin M Kennedy, Janet Titzler, Avani Ganesan, Craig Yamaguchi, Michelle Zuniga-Hernandez, Meghana Renavikar, Ryan Brinda, Christian Jackson, Stacie Rohovit, Thomas J Caruso

Background: Anxiety is common in pediatric patients, especially during vascular access procedures. Most well-studied affect and anxiety scales, including the Observation Scale of Behavioral Distress-Revised (OSBD-r), the modified Yale Preoperative Anxiety Scale (mYPAS), and the modified Induction Compliance Checklist (mICC), are too cumbersome for clinical use outside of research settings. HRAD± (Happy, Relaxed, Anxious, Distressed with yes/no to cooperation) is a clinically-efficient observational scale that evaluates pediatric procedural affect and cooperation. This study examined the clinical utility of HRAD± during vascular access procedures in children. The aims were to investigate the correlation of HRAD± to highly reliable, research-based affect and cooperation scales and to assess inter-rater reliability (IRR) between observers in this setting.

Methods: This was a prospective, observational study conducted at Lucile Packard Children's Hospital Stanford. Inpatient participants were 1 month to 25 years old and undergoing a peripheral intravenous insertion or phlebotomy. Two trained research assistants (RAs) scored each patient independently during the vascular access procedure using HRAD±, OSBD-r, mYPAS, and mICC. Correlation analyses computed the associations between HRAD± and reference scales. IRR between RAs and vascular access providers was calculated using Fleiss' Kappa.

Results: A total of 234 patients were included. HRAD± scores strongly correlated with OSBD-r and mYPAS (p < 0.0001, p < 0.0001, respectively). The cooperation assessment of HRAD± demonstrated strong correlation to mICC (p < 0.0001). IRR of HRAD± between research assistants and vascular access providers showed moderate agreement (p < 0.0001).

Conclusion: HRAD± demonstrated strong correlation to the reference affect and cooperation scales. This study supports the utility of HRAD± for rapid assessment of pediatric procedural anxiety and cooperation during vascular access procedures. HRAD± can serve as a practical tool for facilitating clinical decisions, and its wider incorporation into healthcare settings would importantly guide targeted interventions to reduce patient anxiety.

背景:焦虑在儿科患者中很常见,尤其是在血管通路手术过程中。大多数被充分研究过的情绪和焦虑量表,包括行为困扰观察量表修订版(osdb -r)、耶鲁术前焦虑量表修订版(mYPAS)和诱导依从性检查表修订版(mICC),在研究环境之外的临床应用中都过于繁琐。HRAD±(快乐、放松、焦虑、痛苦与合作是/否)是一种临床有效的观察量表,用于评估儿科手术影响和合作。本研究考察了HRAD±在儿童血管通路手术中的临床应用。目的是调查HRAD±与高可靠的、基于研究的影响和合作量表的相关性,并评估在这种情况下观察者之间的评价信度(IRR)。方法:这是一项在斯坦福大学露西尔·帕卡德儿童医院进行的前瞻性观察性研究。住院患者年龄1个月至25岁,接受外周静脉插入或静脉切开术。两名训练有素的研究助理(RAs)在血管通路过程中使用HRAD±、OSBD-r、mYPAS和mICC对每位患者进行独立评分。相关性分析计算了HRAD±与参考量表之间的相关性。使用Fleiss' Kappa计算RAs与血管通路提供者之间的IRR。结果:共纳入234例患者。结论:HRAD±得分与参考情绪量表、合作量表有较强的相关性。本研究支持HRAD±在快速评估儿童血管通路过程中的手术焦虑和合作方面的效用。had±可以作为促进临床决策的实用工具,将其广泛纳入医疗保健环境将重要地指导有针对性的干预措施,以减少患者的焦虑。
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引用次数: 0
Endovascular management of central venous catheter induced superior vena cava syndrome. 中心静脉导管致上腔静脉综合征的血管内处理。
IF 1.6 3区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-12-05 DOI: 10.1177/11297298241303191
Brigitte Anderson, Vashisht Madabhushi, Alison Flentje, Javaneh Jabbari, Mirnal Chaudhary, Joel Harding, Khanjan Nagarsheth

This case series describes the endovascular management of three patients with catheter-associated superior vena cava (SVC) syndrome. SVC syndrome can result from malignant (60%) or benign (40%) etiologies. The most common causes of benign SVC syndrome are indwelling central venous catheters (CVCs) with 1%-3% and 0.2%-3.3% of patients being affected. In all cases, a mechanical thrombectomy device was used to evacuate the chronic and acute thrombus, followed by a balloon angioplasty and stenting of the SVC. Anterograde flow and rapid symptom resolution was achieved following the procedure. No peri- or postprocedural complications occurred. These cases demonstrate the feasibility of endovascular management of catheter-associated SVC syndrome.

本病例系列描述了3例导管相关上腔静脉(SVC)综合征患者的血管内处理。SVC综合征可由恶性(60%)或良性(40%)病因引起。良性SVC综合征最常见的原因是留置中心静脉导管(CVCs),分别占患者的1%-3%和0.2%-3.3%。在所有病例中,使用机械取栓装置排出慢性和急性血栓,然后进行球囊血管成形术和SVC支架置入术。顺行血流和快速症状解决后实现的程序。手术前后无并发症发生。这些病例证明了导管相关SVC综合征的血管内治疗的可行性。
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引用次数: 0
Port malposition in the anterior mediastinum resulting in chemotherapy extravasation into the pleural cavity: A case report and literature review. 前纵隔端口错位导致化疗药物外渗胸腔:1例报告并文献复习。
IF 1.6 3区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-12-05 DOI: 10.1177/11297298241303202
Jiaobo He

We present a rare case of port malposition into the anterior mediastinum resulting in chemotherapy extravasation into the pleural cavity. While management of extravasation into soft tissues has been established, the data on treatment of mediastinal and intrapleural extravasation is limited. This case underscores how utilizing state-of-the-art technology like real-time intracavitary electrocardiography(IC-ECG) or transthoracic/subxiphoid ultrasound with the "bubble test", rather than reliance on postoperative chest radiography, can help eliminate catheter malposition and its potential catastrophic consequences.

我们报告一个罕见的病例端口错位进入前纵隔导致化疗外渗到胸膜腔。虽然已经建立了软组织外渗的管理,但纵隔和胸膜内外渗的治疗数据有限。本病例强调了如何利用最先进的技术,如实时腔内心电图(IC-ECG)或经胸/剑突下超声与“气泡试验”,而不是依赖于术后胸部x线摄影,可以帮助消除导管错位及其潜在的灾难性后果。
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引用次数: 0
A uremic patient with autogenous arteriovenous fistula developed tension blisters after initial puncture. 一例尿毒症患者自体动静脉瘘首次穿刺后出现张力性水泡。
IF 1.6 3区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-12-02 DOI: 10.1177/11297298241300657
Yingdong Guo, Lili Wang, Liming Liang, Zunsong Wang, Shiyong Qin, Xianglei Kong

Tension blisters usually occur in the presence of local swelling or excessive pressure. Tension blisters after puncture injury are relatively rare in uremic patients who use autogenous arteriovenous fistula (AVF) for hemodialysis treatment. In this report, the patient we reported developed tension blisters after the initial puncture injury. Arterial CTA revealed obvious stenosis of the right subclavian vein and the patient was diagnosed with venothoracic outlet syndrome (VTOS). In this case, the occurrence and development of tension blisters after dialysis puncture injury were observed. Furthermore, the etiology, treatment measures, and methods for preventing the occurrence of tension blisters are illuminated to further improve the quality of vascular access.

张力性水泡通常发生在局部肿胀或压力过大的情况下。在使用自体动静脉瘘(AVF)进行血液透析治疗的尿毒症患者中,穿刺损伤后张力性水泡相对罕见。在本报告中,我们报告的患者在最初的穿刺损伤后出现张力性水泡。动脉CTA显示右侧锁骨下静脉明显狭窄,诊断为胸静脉出口综合征(VTOS)。本病例观察透析穿刺损伤后张力性水疱的发生与发展。此外,本文还阐述了张力性水泡的病因、治疗措施和预防方法,以进一步提高血管通路的质量。
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引用次数: 0
Endovascular treatment of upper limb phlegmasia cerulea dolens in a hemodialysis patient. 1例血液透析患者上肢蓝核痰肿的血管内治疗。
IF 1.6 3区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-12-02 DOI: 10.1177/11297298241301509
Nikolaos Galanakis, Nikolaos Kontopodis, Dimitrios Xydakis, Eleni Tzali, Dimitrios Tsetis, Elias Kehagias

Phlegmasia cerulea dolens (PCD) is a rare but limb-threatening complication of deep vein thrombosis. A 72-year-old hemodialysis male patient presented with upper limb PCD. The patient underwent hemodialysis via a permanent hemodialysis central venous catheter (HD-CVC) while a new brachial-cephalic AVF was created 1 month ago. Computed tomography revealed extensive thrombosis of right subclavian and brachiocephalic vein. The HD-CVC was removed and patient was treated with anticoagulation therapy. However, his clinical condition was worsening and he was transferred to IR department. The patient underwent successful percutaneous pharmacomechanical thrombectomy (PMT) of the right subclavian and brachiocephalic vein followed by percutaneous angioplasty (PTA) with significant flow restoration and no signs of pulmonary embolization. PCD may also be developed in hemodialysis patients with well-functioned AVF. Effective and rapid revascularization is important to prevent serious complications such as venous gangrene and limb ischemia. Endovascular treatment with PMT and PTA can be a limb-saving procedure for rapid recanalization in patients with PCD.

摘要蓝斑痰症是一种罕见但危及肢体的深静脉血栓并发症。一位72岁男性血液透析患者以上肢PCD为主诉。患者通过永久性血液透析中心静脉导管(HD-CVC)进行血液透析,并于1个月前创建了一个新的肱-头侧AVF。计算机断层扫描显示右侧锁骨下及头臂静脉广泛血栓形成。切除HD-CVC,给予抗凝治疗。然而,他的临床情况恶化,他被转移到IR科。患者成功接受了右锁骨下静脉和头臂静脉经皮药物力学取栓术(PMT),随后进行了经皮血管成形术(PTA),血流恢复明显,无肺栓塞迹象。血液透析患者AVF功能良好时也可能发生PCD。有效、快速的血运重建对于预防静脉坏疽和肢体缺血等严重并发症至关重要。PMT和PTA的血管内治疗对于PCD患者的快速再通是一种挽救肢体的方法。
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引用次数: 0
International experts consensus on optimal central vascular access device selection and management for patients with cancer. 国际专家对癌症患者最佳中央血管通路装置的选择和管理达成共识。
IF 1.6 3区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-12-02 DOI: 10.1177/11297298241300792
Mohammad Jahanzeb, Ching-Yang Wu, Howard Lim, Kei Muro, Lichao Xu, Manjiri Somashekhar, S P Sampige Prasannakumar Somashekhar, Xiaotao Zhang, Xiaoxia Qiu, Ying Fu, Mauro Pittiruti

Background: In patients with cancer, the choice of an appropriate venous access device is crucial for effective treatment, minimizing complications, and reducing healthcare costs. Key management decisions, such as the timing of device removal post-therapy, can impact clinical outcomes. As current international guidelines lack specific directives for these issues, a global consensus of experts, representing different countries, was deemed appropriate.

Methods: A panel of 11 experts from three continents, including oncologists and healthcare professionals, was chosen. After a comprehensive review of clinical trials and guidelines on central venous access devices (CVAD) in oncology published between January 2013 and December 2023, the panel developed and voted on specific recommendations for the selection and management of CVADs in patients with cancer, during a 2-day meeting.

Results: The panel reached consensus on 10 issues concerning (a) indications for a CVAD, (b) available options for CVADs, (c) role of the staff and patients in the choice of CVAD, (d) factors influencing the selection of a port over an external catheter, (e) logistical requirements for port and external catheter insertion, (f) stakeholders responsible for port and external catheter insertion, (g) factors determining the removal of a port after completing the definitive therapy, and (h) recommended frequency of flushing when the CVAD is not in use.

Conclusions: The results of the consensus may offer healthcare professionals a global view of some critical issues concerning CVADs for cancer therapy, helping to establish recommendations for local clinical practice.

背景:在癌症患者中,选择合适的静脉通路装置对于有效治疗、减少并发症和降低医疗费用至关重要。关键的管理决策,如治疗后器械移除的时间,可以影响临床结果。由于目前的国际准则缺乏针对这些问题的具体指示,代表不同国家的专家达成全球共识被认为是适当的。方法:选择了来自三大洲的11位专家,包括肿瘤学家和医疗保健专业人员。在对2013年1月至2023年12月期间发表的肿瘤中心静脉通路装置(CVAD)的临床试验和指南进行全面审查后,该小组在为期2天的会议上制定并投票了针对癌症患者中心静脉通路装置的选择和管理的具体建议。结果:专家组就10个问题达成共识,涉及(a) CVAD的适应症,(b) CVAD的可用方案,(c)工作人员和患者在CVAD选择中的作用,(d)影响选择端口而非外部导管的因素,(e)端口和外部导管插入的后勤要求,(f)负责端口和外部导管插入的利益相关者,(g)完成最终治疗后决定移除端口的因素。(h)当CVAD不使用时,建议的冲洗频率。结论:共识的结果可能为医疗保健专业人员提供有关心血管疾病治疗癌症的一些关键问题的全球观点,有助于为当地临床实践建立建议。
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引用次数: 0
Impact of aspirin on the outcome of upper limb AVF placement in hemodialysis patients: Discontinuation or not. 阿司匹林对血液透析患者上肢AVF置放结果的影响:是否停用。
IF 1.6 3区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-12-01 DOI: 10.1177/11297298241301527
Behzad Azimi, Mohammad Mozaffar, Sina Soleimani, Behnaz Mousavi, Alireza Haghbin Toutounchi

Background: There is limited research on the consumption of aspirin and its effects on bleeding during arteriovenous fistula (AVF) placement surgery and associated complications in end-stage renal disease (ESRD) patients. Regarding the potential risks imposed on cardiac patients by discontinuing aspirin, the aim of the study was to determine whether aspirin should be discontinued prior to AVF placement surgery.

Methods: This prospective study was carried out at two referral medical centers from 2023 to 2024. The patients were included as 30 patients who routinely took 80 mg of aspirin daily and 30 patients who did not take aspirin. The primary outcomes included the amount of blood loss, and the secondary outcomes included AVF success and maturation time. The amount of bleeding was assessed by the ΔHb (Hb1-Hb2), ΔHCT (HCT1-HCT2), and intraoperative hemorrhage volume.

Results: Aspirin consumption did not significantly affect any of the examined parameters, including operation duration, hemoglobin decrease, hematocrit decrease, intraoperative hemorrhage, AVF success rate, maturity time, need for blood transfusion, postoperative bleeding, hematoma and thrombosis, hospitalization, and re-Operation (p > 0.05).

Conclusion: Aspirin did not have any significant or negative effects across any of the parameters examined. Based on the findings of this study, there is no need to discontinue aspirin in patients prior to upper limb AVF placement surgery, but further studies are recommended.

背景:终末期肾病(ESRD)患者在动静脉瘘(AVF)置入术中服用阿司匹林及其对出血的影响和相关并发症的研究有限。关于停用阿司匹林对心脏病患者的潜在风险,本研究的目的是确定在AVF置放手术前是否应该停用阿司匹林。方法:本前瞻性研究于2023年至2024年在两家转诊医疗中心进行。这些患者包括30名每天常规服用80毫克阿司匹林的患者和30名不服用阿司匹林的患者。主要结局包括出血量,次要结局包括AVF成功和成熟时间。通过ΔHb (Hb1-Hb2)、ΔHCT (HCT1-HCT2)和术中出血量评估出血量。结果:阿司匹林用量对手术时间、血红蛋白下降、红细胞压积下降、术中出血、AVF成功率、成熟时间、输血需求、术后出血、血肿及血栓形成、住院、再手术等各项指标无显著影响(p < 0.05)。结论:阿司匹林在检查的所有参数中没有任何显著的或负面的影响。基于本研究结果,在上肢AVF置入术前,患者无需停用阿司匹林,但建议进一步研究。
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引用次数: 0
期刊
Journal of Vascular Access
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