Pub Date : 2021-06-01DOI: 10.13491/J.ISSN.1004-714X.2021.03.014
Xie Xin, L. Liang, Fan Xuemei, XU Yumei, Sha Guanchen, Liu Xiaoxiao
Objective The purpose of this study is to provide a reference for the selection of clinical radiotherapy plan by comparing the difference of dosimetry between coplanar dynamic intensity modulation dIMRT and coplanar VMAT plan in hippocampal protective whole brain radiotherapy (WBRT). Methods 10 patients were selected whose hippocampal were protected by WBRT, dIMRT and VMAT plans were designed for each patient, the differences of target dose, organ-endangering dose and machine hop count were compared between the two groups. Results The two technical plans PTV V 30 Gy , D 98% and D 2% all meet the standard of RTOG 0933, which is better than the dIMRT group for the PTV HI VMAT group ( P = 0.04), The hippocampal dose of dIMRT group was better than that of VMAT group, but it did not meet the standard of RGOT 0933. The average D max of hippocampus in dIMRT group and VMAT group was 18.44 Gy and 19.30 Gy, respectively ( P = 0.004). The average value of hippocampal D min was 10.03 Gy and 10.77 Gy, respectively ( P = 0.013), and the mean value of hippocampal D mean was 14.20 Gy and 15.12 Gy, respectively ( P = 0.002). The doses of lens, eyeball and optic nerve all met the standard of RTOG0933, and the dose of dIMRT group was significantly better than that of VMAT group ( P = 0.000). The treatment time in VMAT group was significantly lower than that in dIMRT group. The treatment time in VMAT group was significantly lower than that in dIMRT group. Conclusion Varian dIMRT has more advantages in controlling hippocampal dose and protecting lens than VMAT, but PTV HI and treatment efficiency are higher in VMAT group. 摘要： 目的 通过比较 Varian 加速器共面动态调强 dIMRT 与共面 VMAT 计划在海马保护全脑放疗 (WBRT) 中剂量 学差异, 为临床放疗计划选择提供一种依据。 方法 10 例海马保护 WBRT 患者, 每名患者均设计 dIMRT 与 VMAT 计划, 比较两者靶区剂量、危及器官剂量和机器跳数的差异;。 结果 2 种技术计划 PTV V 30 Gy 、 D 98% 和 D 2% 均 符合 RTOG 0933 标准, 对于 PTV HI VMAT 组优于 dIMRT 组 ( P = 0.004)。海马剂量 dIMRT 组优于 VMAT 组, 但均 未达到 RGOT 0933 标准: dIMRT 组与 VMAT 组海马 D max 均值分别为 18.44 Gy 和 19.30 Gy, 有统计学差异 ( P = 0.04); 海马 D min 均值分别为 10.03 Gy 和 10.77 Gy, 有统计学差异 ( P = 0.013); 海马 D mean 均值分别为 14.20 Gy 和 15.12 Gy, 有统计学差异 ( P = 0.002)。晶体、眼球和视神经剂量均符合 RTOG 0933 标准, dIMRT 组也明显优于 VMAT 组, 均 P = 0.000。VMAT 组治疗时间低于 dIMRT 组。 结论 Varian dIMRT 相比 VMAT 控制海马剂量和保护 晶体更有优势, 但 VMAT 组 PTV HI 和治疗效率更高。
{"title":"Dosimetric study of hippocampal protective whole brain radiotherapy based on Varian accelerator","authors":"Xie Xin, L. Liang, Fan Xuemei, XU Yumei, Sha Guanchen, Liu Xiaoxiao","doi":"10.13491/J.ISSN.1004-714X.2021.03.014","DOIUrl":"https://doi.org/10.13491/J.ISSN.1004-714X.2021.03.014","url":null,"abstract":"Objective The purpose of this study is to provide a reference for the selection of clinical\u0000 radiotherapy plan by comparing the difference of dosimetry between coplanar dynamic\u0000 intensity modulation dIMRT and coplanar VMAT plan in hippocampal protective whole\u0000 brain radiotherapy (WBRT).\u0000 Methods 10 patients were selected whose hippocampal were protected by WBRT, dIMRT and VMAT\u0000 plans were designed for each patient, the differences of target dose, organ-endangering\u0000 dose and machine hop count were compared between the two groups.\u0000 Results The two technical plans PTV V\u0000 30 Gy\u0000 , D\u0000 98% and D\u0000 2%\u0000 all meet the standard of RTOG 0933, which is better than the dIMRT group for the\u0000 PTV HI VMAT group (\u0000 P = 0.04), The hippocampal dose of dIMRT group was better than that of VMAT group,\u0000 but it did not meet the standard of RGOT 0933. The average D\u0000 max\u0000 of hippocampus in dIMRT group and VMAT group was 18.44 Gy and 19.30 Gy, respectively\u0000 (\u0000 P = 0.004). The average value of hippocampal D\u0000 min\u0000 was 10.03 Gy and 10.77 Gy, respectively (\u0000 P = 0.013), and the mean value of hippocampal D\u0000 mean was 14.20 Gy and 15.12 Gy, respectively (\u0000 P = 0.002). The doses of lens, eyeball and optic nerve all met the standard of RTOG0933,\u0000 and the dose of dIMRT group was significantly better than that of VMAT group (\u0000 P = 0.000). The treatment time in VMAT group was significantly lower than that in dIMRT\u0000 group. The treatment time in VMAT group was significantly lower than that in dIMRT\u0000 group.\u0000 Conclusion Varian dIMRT has more advantages in controlling hippocampal dose and protecting lens\u0000 than VMAT, but PTV HI and treatment efficiency are higher in VMAT group.\u0000 摘要： 目的 通过比较 Varian 加速器共面动态调强 dIMRT 与共面 VMAT 计划在海马保护全脑放疗 (WBRT) 中剂量 学差异, 为临床放疗计划选择提供一种依据。\u0000 方法 10 例海马保护 WBRT 患者, 每名患者均设计 dIMRT 与 VMAT 计划, 比较两者靶区剂量、危及器官剂量和机器跳数的差异;。\u0000 结果 2 种技术计划 PTV V\u0000 30 Gy\u0000 、\u0000 D\u0000 98% 和 D\u0000 2% 均 符合 RTOG 0933 标准, 对于 PTV HI VMAT 组优于 dIMRT 组 (\u0000 P = 0.004)。海马剂量 dIMRT 组优于 VMAT 组, 但均 未达到 RGOT 0933 标准: dIMRT 组与 VMAT 组海马 D\u0000 max 均值分别为 18.44 Gy 和 19.30 Gy, 有统计学差异 (\u0000 P = 0.04); 海马 D\u0000 min 均值分别为 10.03 Gy 和 10.77 Gy, 有统计学差异 (\u0000 P = 0.013); 海马 D\u0000 mean 均值分别为 14.20 Gy 和 15.12 Gy, 有统计学差异 (\u0000 P = 0.002)。晶体、眼球和视神经剂量均符合 RTOG 0933 标准, dIMRT 组也明显优于 VMAT 组, 均 P = 0.000。VMAT 组治疗时间低于 dIMRT 组。\u0000 结论 Varian dIMRT 相比 VMAT 控制海马剂量和保护 晶体更有优势, 但 VMAT 组 PTV HI 和治疗效率更高。","PeriodicalId":58844,"journal":{"name":"中国辐射卫生","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48230172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.13491/J.ISSN.1004-714X.2021.03.018
Luo Yunman, Wang Jiping, H. Wei, Chen Chuanxi, Yang Guodong, W. Ping, Yang Zhiyong
Objective To compare the dosimetric characteristics of non-coplanar and coplanar field technology in static intensity-modulated radiotherapy of gastric cancer patients, so as to provide a reference for clinical radiotherapy plan selection. Methods Thirty-six patients with gastric cancer were selected to receive intensity-modulated radiotherapy in Huanggang Central Hospital, which was designed plan A and B. Group A used 7-field coplanar technology, while Group B used 7-fleld non-coplanar technology. We compared the differences of the optimized monitor unit, the dosimetry of organs at risk and target areas between group A and group B. Results Both group A and B could meet the requirements of doctors. The homogeneity index (0.14 ± 0.02), the conformity index (0.98 ± 0.01), D min (4 315.21 ± 16.74) cGy, D mean (4 679.28 ± 28.39) cGy and D max (4 952.30 ± 33.26) cGy of target areas in group B were better than those of group A. Moreover, the monitor unit of group B was much lower than that of group A, and the difference was statistically significant ( P < 0.05). The D max, D mean, V 15, V 20 and V 30 of the left and right kidneys in group B were lower than those of group A. The D max (3 408.57 ± 46.03) cGy, D mean (1 250.32 ± 14.27) cGy and V 20 (44.91% ± 6.67%) of spinal cord and the D max (3 408.57 ± 46.03) cGy, D mean (1 720.55 ± 17.42) cGy, V 20 (25.31% ± 7.78%) and V 30 (18.52% ± 1.56%) of small intestine were also lower than those of group A. The differences were statistically significant ( P < 0.05). Conclusion The non-coplanar field radiation plan has more advantages in terms of target dose distribution and protection of organs so that it can be more considerably used in the process of planning and design. 摘要： 目的 通过比较非共面射野与共面射野计划在胃癌静态调强中的剂量学特点, 为临床放疗计划选择提供依 据。 方法 选取黄冈市中心医院接受调强放射治疗的胃癌患者 36 例, 每名患者均设计A、B 2 组计划, A 组采用 7 野 共面技术, B 组采用 7 野非共面技术, 比较 A 组和 B 组优化后机器跳数、危及器官和靶区的剂量学差异。 结果 A、B 两组计划均能满足医生要求, B 组靶区均匀性指数 HI (0.14 ± 0.02)和适形度指数 CI (0.98 ± 0.01), 靶区 D min (4 315.21 ± 16.74) cGy, D mean (4 679.28 ± 28.39) cGy 和 D max (4 952.30 ± 33.26) cGy 均优于 A 组, 且 B 组机器跳数更 少, 差异有统计学意义 ( P < 0.05)。B 组左右侧肾脏 D max、 D mean、 V 15、 V 20 和 V 30均低于A组, 脊髓的 D max (3 408.57 ± 46.03) cGy、 D mean (1 250.32 ± 14.27) cGy 和 V 20 (44.91% ± 6.67%)以及小肠的 D max (3 408.57 ± 46.03) cGy、 D mean (1 720.55 ± 17.42) cGy、 V 20 (25.31% ± 7.78%) 和 V 30 18.52% ± 1.56%)也均低于 A 组, 差异有统计学意义 ( P < 0.05)。 结论 非共面射野计划在靶区剂量分布和危及器官保护上更优, 计划设计过程中可以更多的考虑非共面布野技术。
{"title":"Dosimetric investigation of non-coplanar field technology in static intensity-modulated radiation therapy for gastric carcinoma","authors":"Luo Yunman, Wang Jiping, H. Wei, Chen Chuanxi, Yang Guodong, W. Ping, Yang Zhiyong","doi":"10.13491/J.ISSN.1004-714X.2021.03.018","DOIUrl":"https://doi.org/10.13491/J.ISSN.1004-714X.2021.03.018","url":null,"abstract":"Objective To compare the dosimetric characteristics of non-coplanar and coplanar field technology\u0000 in static intensity-modulated radiotherapy of gastric cancer patients, so as to provide\u0000 a reference for clinical radiotherapy plan selection.\u0000 Methods Thirty-six patients with gastric cancer were selected to receive intensity-modulated\u0000 radiotherapy in Huanggang Central Hospital, which was designed plan A and B. Group\u0000 A used 7-field coplanar technology, while Group B used 7-fleld non-coplanar technology.\u0000 We compared the differences of the optimized monitor unit, the dosimetry of organs\u0000 at risk and target areas between group A and group B.\u0000 Results Both group A and B could meet the requirements of doctors. The homogeneity index\u0000 (0.14 ± 0.02), the conformity index (0.98 ± 0.01), D\u0000 min (4 315.21 ± 16.74) cGy, D\u0000 mean (4 679.28 ± 28.39) cGy and D\u0000 max (4 952.30 ± 33.26) cGy of target areas in group B were better than those of group\u0000 A. Moreover, the monitor unit of group B was much lower than that of group A, and\u0000 the difference was statistically significant (\u0000 P < 0.05). The D\u0000 max, D\u0000 mean, V\u0000 15, V\u0000 20 and V\u0000 30 of the left and right kidneys in group B were lower than those of group A. The D\u0000 max (3 408.57 ± 46.03) cGy, D\u0000 mean (1 250.32 ± 14.27) cGy and V\u0000 20 (44.91% ± 6.67%) of spinal cord and the D\u0000 max (3 408.57 ± 46.03) cGy, D\u0000 mean (1 720.55 ± 17.42) cGy, V\u0000 20 (25.31% ± 7.78%) and V\u0000 30 (18.52% ± 1.56%) of small intestine were also lower than those of group A. The differences\u0000 were statistically significant (\u0000 P < 0.05).\u0000 Conclusion The non-coplanar field radiation plan has more advantages in terms of target dose\u0000 distribution and protection of organs so that it can be more considerably used in\u0000 the process of planning and design.\u0000 摘要： 目的 通过比较非共面射野与共面射野计划在胃癌静态调强中的剂量学特点, 为临床放疗计划选择提供依 据。\u0000 方法 选取黄冈市中心医院接受调强放射治疗的胃癌患者 36 例, 每名患者均设计A、B 2 组计划, A 组采用 7 野 共面技术, B 组采用 7 野非共面技术, 比较\u0000 A 组和 B 组优化后机器跳数、危及器官和靶区的剂量学差异。\u0000 结果 A、B 两组计划均能满足医生要求, B 组靶区均匀性指数 HI (0.14 ± 0.02)和适形度指数 CI (0.98 ± 0.01), 靶区 D\u0000 min (4 315.21 ± 16.74) cGy, D\u0000 mean (4 679.28 ± 28.39) cGy 和 D\u0000 max (4 952.30 ± 33.26) cGy 均优于 A 组, 且 B 组机器跳数更 少, 差异有统计学意义 (\u0000 P < 0.05)。B 组左右侧肾脏 D\u0000 max、\u0000 D\u0000 mean、\u0000 V\u0000 15、\u0000 V\u0000 20 和 V\u0000 30均低于A组, 脊髓的 D\u0000 max (3 408.57 ± 46.03) cGy、\u0000 D\u0000 mean (1 250.32 ± 14.27) cGy 和 V\u0000 20 (44.91% ± 6.67%)以及小肠的 D\u0000 max (3 408.57 ± 46.03) cGy、\u0000 D\u0000 mean (1 720.55 ± 17.42) cGy、\u0000 V\u0000 20 (25.31% ± 7.78%) 和 V\u0000 30 18.52% ± 1.56%)也均低于 A 组, 差异有统计学意义 (\u0000 P < 0.05)。\u0000 结论 非共面射野计划在靶区剂量分布和危及器官保护上更优, 计划设计过程中可以更多的考虑非共面布野技术。","PeriodicalId":58844,"journal":{"name":"中国辐射卫生","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42967539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.13491/J.ISSN.1004-714X.2021.03.005
You-Chen Tao, L. Chunmei, Dai Chunhua, Cheng Deyu, Dang Jun
Objective This study reconstructed 4D-CBCT for fully automatic compensated sliding motion by incorporating the bilateral filtering into the Deformable Vector Field (DVF). Methods First, a motion compensated simultaneous algebraic reconstruction technique (Modified Simultaneous Algebra Reconstruction Technique, mSART) was used to generate a high quality reference phase by using all phase projection stogether with the initial 4D-DVFs, which were generated via Demons registration between 0% phase and each other phaseimage. The 4D-DVF was optimized by matching the forward projection of the deformed 0% phase with the measured projection of the target phase. The loss function’s DVF smoothing constrain term contained bilateral filtering kernel that contained: 1) an spatial domain Guassian kernel; 2) animage intensity domain Guassian kernel; and 3) a DVF domain Guassian kernel. By choosing suitable kernel variances, the sliding motion can be extracted. A non-linear conjugate gradient optimizer wasused. We validated the algorithm on a Non-Uniform Rotational B-spline based Cardiac-Torso (NCAT) phantom. Quantification was evaluated by: 1) the Root-Mean-Square-Error (RMSE) together with the Maximum-Error (MaxE); 2) the Dice coefficient of the extracted lung contour from the final reconstructed images and 3) the relative reconstruction error (RE) to evaluate the algorithm’s performance. Results The motion trajectory’s RMSE/MaxEare 0.796/1.02 mm for bilateral filtering reconstruction; and 2.704/4.08 mm for original reconstruction. Image content such a stherib position, the hearted gedefinition, the fibrous structures all had been better corrected with bilateral filtering. Conclusion We developed a bilateral filtering based fully automatic sliding motion compensated 4D-CBCT scheme. Digital phantom study confirmed the improved motion estimation and image reconstruction ability. It can be used as a 4D-CBCT image guidance tool for lung SBRT treatment. 摘要： 目的 将双边滤波引入基于可变形矢量场 (DVF) 的 4D-CBCT 重建, 实现全自动滑动运动补偿 4D-CBCT 重 建。 方法 首先利用所有相位投影, 用改良的运动补偿瞬时代数重建技术 (Modified Simultaneous Algebra Reconstruction Technique, mSART) 生成高质 量参考相位。初始 4D-DVF 通过 0% 相位和其他相位图像依次配准生成。之后通过 配准目标相位测量投影和参考相位变形到目标相位后的正投来优化求解 4D-DVF。优化过程中的损失函数平滑约束 项中引入双边滤波。其包含 3 个子核:空间域 Guassian 核; 图像强度域 Guassian 核; 和 DVF 域 Guassian 核。选择合适 的子核方差提取滑动运动, 采用非线性共轭梯度算子优化, 用 B 样条心脏躯干体模 (NURBS-based Cardiac-Torso phantom, NCAT phantom) 验证算法。采用量化评价指标: Root-Mean-Square-Error (RMSE) 和最大误差 (MaxE); 重建图 像提取的肺轮廓 Dice 系数和相对重建误差 (RE) 评价算法性能。 结果 NCAT 模体的双边滤波重建运动轨迹的 RMSE/MaxE 为 0.796/1.02 mm; 原始重建方法的相应结果为 2.704/4.08 mm。图像中的特定结构如肋骨位置, 心脏边缘 的定义, 纤维结构通过双边过滤都得到了更好的纠正。 结论 开发了一种基于双边滤波的全自动滑动运动补偿 4D-CBCT 方案, 数字模体研宄证实了改进的运动估计和图像重建能力, 其可被用作肺 SBRT 治疗的 4D-CBCT 图像引 导工具。
Objective This study reconstructed 4D-CBCCT for fully automated compensated sliding motion by incorporating the bile filtering into the Deformable Vector Field (DVF) Methods First, a motion compensated simultaneous algebraic reconstruction technique (Modified Simultaneous Algebra Reconstruction Technique, mSART) was used to generate a high quality reference phase by using all phase projections together with the initial 4D-DVF, which were generated via Demons registration between 0% phase and each other phase image The 4D-DVF was optimized by matching the forward project of the deformed 0% phase with the measured project of the target phase The loss function's DVF smoothing constraint term contained bilateral filtering kernel that contained: 1) an spatial domain Gaussian kernel; 2) Image intensity domain Gaussian kernel; And 3) a DVF domain Guassian kernel By choosing suitable kernel variations, the sliding motion can be extracted A non linear conjugate gradient optimizer wasted We validated the algorithm on a Non Uniform Rotational B-spline based Cardiac Torso (NCAT) phantom Quantification was evaluated by: 1) the Root Mean Square Error (RMSE) together with the Maximum Error (MaxE); 2) The Dice coefficient of the extracted lung resource from the final reconstructed images and 3) the relative reconstruction error (RE) to evaluate the algorithm's performance Results The motion trajectory's RMSE/MaxEarth 0.796/1.02 mm for bilateral filtering reconstruction; And 2.704/4.08 mm for original reconstruction Image content such as a sterib position, the heated gedefinition, the fibrous structures all had been better corrected with bilateral filtering Conclusion We developed a bilateral filtering based fully automatic sliding motion compensated 4D-CBCCT scheme Digital phantom study confirmed the improved motion estimation and image reconstruction capability It can be used as a 4D-CBCCT image guidance tool for lung SBRT treatment Abstract: The purpose is to introduce bilateral filtering into 4D-CBCCT reconstruction based on Deformable Vector Field (DVF), and achieve fully automatic sliding motion compensation 4D-CBCCT reconstruction. The method first utilizes all phase projections and generates high-quality reference phases using an improved motion compensated instantaneous algebraic reconstruction technique (mSART). The initial 4D-DVF is generated by sequentially registering 0% phase and other phase images. Afterwards, the 4D-DVF is optimized by registering the target phase measurement projection and deforming the reference phase to the forward projection of the target phase. Introducing bilateral filtering in the smoothing constraint of the loss function during the optimization process. It contains three sub kernels: the spatial domain Guassian kernel; Image intensity domain Guassian kernel; And DVF domain Guassian core. Select the appropriate sub kernel variance to extract sliding motion, optimize using nonlinear conjugate gradient operator, and validate
{"title":"Bilateral filtering based sliding motion compensated 4D-CBCT: a simulation study","authors":"You-Chen Tao, L. Chunmei, Dai Chunhua, Cheng Deyu, Dang Jun","doi":"10.13491/J.ISSN.1004-714X.2021.03.005","DOIUrl":"https://doi.org/10.13491/J.ISSN.1004-714X.2021.03.005","url":null,"abstract":"Objective This study reconstructed 4D-CBCT for fully automatic compensated sliding motion by\u0000 incorporating the bilateral filtering into the Deformable Vector Field (DVF).\u0000 Methods First, a motion compensated simultaneous algebraic reconstruction technique (Modified\u0000 Simultaneous Algebra Reconstruction Technique, mSART) was used to generate a high\u0000 quality reference phase by using all phase projection stogether with the initial 4D-DVFs,\u0000 which were generated via Demons registration between 0% phase and each other phaseimage. The 4D-DVF was optimized\u0000 by matching the forward projection of the deformed 0% phase with the measured projection\u0000 of the target phase. The loss function’s DVF smoothing constrain term contained bilateral\u0000 filtering kernel that contained: 1) an spatial domain Guassian kernel; 2) animage\u0000 intensity domain Guassian kernel; and 3) a DVF domain Guassian kernel. By choosing\u0000 suitable kernel variances, the sliding motion can be extracted. A non-linear conjugate\u0000 gradient optimizer wasused. We validated the algorithm on a Non-Uniform Rotational\u0000 B-spline based Cardiac-Torso (NCAT) phantom. Quantification was evaluated by: 1) the\u0000 Root-Mean-Square-Error (RMSE) together with the Maximum-Error (MaxE); 2) the Dice\u0000 coefficient of the extracted lung contour from the final reconstructed images and\u0000 3) the relative reconstruction error (RE) to evaluate the algorithm’s performance.\u0000 Results The motion trajectory’s RMSE/MaxEare 0.796/1.02 mm for bilateral filtering reconstruction;\u0000 and 2.704/4.08 mm for original reconstruction. Image content such a stherib position,\u0000 the hearted gedefinition, the fibrous structures all had been better corrected with\u0000 bilateral filtering.\u0000 Conclusion We developed a bilateral filtering based fully automatic sliding motion compensated\u0000 4D-CBCT scheme. Digital phantom study confirmed the improved motion estimation and\u0000 image reconstruction ability. It can be used as a 4D-CBCT image guidance tool for\u0000 lung SBRT treatment.\u0000 摘要： 目的 将双边滤波引入基于可变形矢量场 (DVF) 的 4D-CBCT 重建, 实现全自动滑动运动补偿 4D-CBCT 重 建。\u0000 方法 首先利用所有相位投影, 用改良的运动补偿瞬时代数重建技术 (Modified Simultaneous Algebra Reconstruction Technique,\u0000 mSART) 生成高质 量参考相位。初始 4D-DVF 通过 0% 相位和其他相位图像依次配准生成。之后通过 配准目标相位测量投影和参考相位变形到目标相位后的正投来优化求解\u0000 4D-DVF。优化过程中的损失函数平滑约束 项中引入双边滤波。其包含 3 个子核:空间域 Guassian 核; 图像强度域 Guassian 核; 和 DVF 域\u0000 Guassian 核。选择合适 的子核方差提取滑动运动, 采用非线性共轭梯度算子优化, 用 B 样条心脏躯干体模 (NURBS-based Cardiac-Torso\u0000 phantom, NCAT phantom) 验证算法。采用量化评价指标: Root-Mean-Square-Error (RMSE) 和最大误差 (MaxE);\u0000 重建图 像提取的肺轮廓 Dice 系数和相对重建误差 (RE) 评价算法性能。\u0000 结果 NCAT 模体的双边滤波重建运动轨迹的 RMSE/MaxE 为 0.796/1.02 mm; 原始重建方法的相应结果为 2.704/4.08 mm。图像中的特定结构如肋骨位置,\u0000 心脏边缘 的定义, 纤维结构通过双边过滤都得到了更好的纠正。\u0000 结论 开发了一种基于双边滤波的全自动滑动运动补偿 4D-CBCT 方案, 数字模体研宄证实了改进的运动估计和图像重建能力, 其可被用作肺 SBRT 治疗的 4D-CBCT\u0000 图像引 导工具。","PeriodicalId":58844,"journal":{"name":"中国辐射卫生","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43465187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.13491/J.ISSN.1004-714X.2021.03.025
Liu Yulong, Ma Nan
Tritium ( 3H) is an isotope of hydrogen. The main sources in the environment are natural tritium and artificial tritium. Artificially produced tritium appears as a by-product or a key fuel in the development of nuclear energy, and its release rate far exceeds that of natural tritium. The public’s exposure to tritium in the environment is very low. Strategically speaking, the protection of tritium should focus on occupational exposure workers. This article briefly summarizes the nature, source, hazards, protection and pollution treatment of tritium, so that the public and radiation workers can understand relevant knowledge and do personal protection. 摘要： 氚 ( 3H)是氢的同位素, 在环境中的主要来源有天然氚和人工氚。人工氚作为一种副产物或关键燃料在人类发 展核能产业中出现, 其释放率远远超过天然氚。公众在环境中摄入氚的水平很低, 从策略上讲氚的防护应重点关注职 业照射人员。本文简要概述了氣的性质、来源、危害、防护及污染处理等, 使公众及放射工作人员了解相关知识, 做好 个人防护。
Tritium ( 3H) is an isotope of hydrogen. The main sources in the environment are natural tritium and artificial tritium. Artificially produced tritium appears as a by-product or a key fuel in the development of nuclear energy, and its release rate far exceeds that of natural tritium. The public’s exposure to tritium in the environment is very low. Strategically speaking, the protection of tritium should focus on occupational exposure workers. This article briefly summarizes the nature, source, hazards, protection and pollution treatment of tritium, so that the public and radiation workers can understand relevant knowledge and do personal protection. 摘要： 氚 ( 3H)是氢的同位素, 在环境中的主要来源有天然氚和人工氚。人工氚作为一种副产物或关键燃料在人类发 展核能产业中出现, 其释放率远远超过天然氚。公众在环境中摄入氚的水平很低, 从策略上讲氚的防护应重点关注职 业照射人员。本文简要概述了氣的性质、来源、危害、防护及污染处理等, 使公众及放射工作人员了解相关知识, 做好 个人防护。
{"title":"Tritium protection in the operation of nuclear energy","authors":"Liu Yulong, Ma Nan","doi":"10.13491/J.ISSN.1004-714X.2021.03.025","DOIUrl":"https://doi.org/10.13491/J.ISSN.1004-714X.2021.03.025","url":null,"abstract":"Tritium (\u0000 3H) is an isotope of hydrogen. The main sources in the environment are natural tritium\u0000 and artificial tritium. Artificially produced tritium appears as a by-product or a\u0000 key fuel in the development of nuclear energy, and its release rate far exceeds that\u0000 of natural tritium. The public’s exposure to tritium in the environment is very low.\u0000 Strategically speaking, the protection of tritium should focus on occupational exposure\u0000 workers. This article briefly summarizes the nature, source, hazards, protection and\u0000 pollution treatment of tritium, so that the public and radiation workers can understand\u0000 relevant knowledge and do personal protection.\u0000 摘要： 氚 (\u0000 3H)是氢的同位素, 在环境中的主要来源有天然氚和人工氚。人工氚作为一种副产物或关键燃料在人类发 展核能产业中出现, 其释放率远远超过天然氚。公众在环境中摄入氚的水平很低,\u0000 从策略上讲氚的防护应重点关注职 业照射人员。本文简要概述了氣的性质、来源、危害、防护及污染处理等, 使公众及放射工作人员了解相关知识, 做好 个人防护。","PeriodicalId":58844,"journal":{"name":"中国辐射卫生","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48032019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.13491/J.ISSN.1004-714X.2021.03.015
Wang Yinliang, Wang Huitao, Zheng Anping, Sun Xiaodong, Wang Dong, Liu Haojia, Qin Yongpeng
Objective The literature study the setup errors of head and neck, thoracic, abdominal and pelvic tumors by megavoltage fan-beam CT based image guidance in TOMO-HD to provide the margin enlarging from clinic target volume (CTV) to planning target volume (PTV) in treatment planning system of TOMO-HD. Methods 103 patients with head and neck (30 patients), thoracic (42 patients), abdominal and pelvic (31 patients) carcinoma were enrolled. Megavoltage fan-beam CT based image guidance in tomotherapy-HD was used to acquire CT scan before every treatment. The left-right (X), superior-inferior (Y), anterior-posterior (Z) and rotation (Fy) setup errors of patients can be obtained from the tomography image automatically restructured by the system. Calculating the systematic error and the random error in the three dimensions and check whether the setup data accord with the normal distribution or not, then acquire the data expand in the three directions. Results According to 2 593 fan-beam CT scans, the shift errors (µ ± s) in X, Y, Z and Fy (rotation) of three study group were [(−0.31 ± 2.16) mm, (1.09 ± 3.56) mm, (2.36 ± 2.27) mm, (0.29 ± 0.96)°] (head and neck tumor), [(−0.98 ± 2.95) mm, (0.45 ± 6.86) mm, (3.79 ± 2.47) mm, (0.18 ± 0.60)°] (thoracic cancer) and [(−0.86 ± 2.85) mm, (−1.59 ± 6.91) mm, (5.77 ± 2.40) mm, (0.20 ± 0.68)°] (abdominal and pelvic carcinoma). The systematic errors (Σ) and random errors (σ) in X, Y, Z dimensions of patients with head and neck, thoracic, abdominal and pelvic tumors were (1.06 mm and 1.84 mm), (1.93 mm and 3.43 mm), (2.41 mm and 2.71 mm), (1.10 mm and 2.56 mm), (3.79 mm and 5.46 mm), (1.38 mm and 1.99 mm) and (1.39 mm and 0.87 mm), (4.98 mm and 5.69 mm), (1.19 mm and 2.05 mm), respectively. Conclusion It is recommended as a reference for image guidance in TOMO-HD according to the frequency distribution of setup errors, for patients with head and neck, chest and abdominal and pelvic tumors, the maximum range of motion in three dimensions are (5.00, 5.00, 5.00) mm, (6,63, 17.25, 16.00) mm and (6.49, 16.24, 13.60) mm. 摘要： 目的 利用 TOMO-HD 螺旋加速器的 MV 级扇形束 CT 研宄头颈部、胸部、腹盆部肿瘤在放疗中的摆位误差, 为 PTV 边界的外扩提供数据支持。 方法 采用 TOMO-HD 螺旋断层系统分别对 30 例头颈部、42 例胸部和 31 例腹盆 部肿瘤患者每次放疗前行 MV 级扇形束 CT 扫描, 系统自动重建图像并与治疗计划 CT 图像进行配准, 获得患者左右 (X 轴)、头脚 (Y 轴)、腹背 (Z 轴)、沿Y轴方向的旋转 (Fy) 方向的摆位误差。计算出X、Y、Z方向的系统误差(Σ) 和随 机误差(σ)并对摆位误差进行正态性检验, 计算出 PTV 的各方向外扩边界。 结果 共行 2 593 次扫描, 头颈部、胸部、腹盆部患者在 X 轴、Y 轴、Z轴、Fy 方向 (沿 Y 轴方向的旋转) 的摆位误差 (µ ± s) 分别为 [(−0.31 ± 2.16)mm、(1.09 ± 3.56)mm、(2.36 ± 2.27)mm、(0.29 ± 0.96)°], [(−0.98 ± 2.95)mm、(−0.45 ± 6.86)mm、(3.79 ± 2.47)mm、(0.18 ± 0.60)°] 和 [(−0.86 ± 2.85)mm、(−1.59 ± 6.91)mm、(5.77 ± 2.40)mm、(0.20 ± 0.68)°]。头颈部、胸部、腹盆部患者在 X 轴、Y 轴、Z轴方向的系统误差(Σ)和随机误差(σ)分别为 (1.06 mm 和 1.84 mm)、(1.93 mm 和 3.43 mm)、(2.41 mm 和 2.71 mm)、(1.10 mm 和 2.56 mm)、(3.79 mm 和 5.46 mm)、(1.38 mm 和 1.99 mm) 和 (1.39 mm 和 0.87 mm)、(4.98 mm 和 5.69 mm)、(1.19 mm 和 2.05 mm)。 结论 根据不同部位的摆位误差频数分布, 头颈部、胸部、腹盆部不同 部位肿瘤患者的靶区在三维方向上最大运动范围参考值为 (5.00, 5.00, 5.00)mm,
{"title":"Study on setup errors for different body carcinoma radiotherapy with image guidance in TOMO-HD","authors":"Wang Yinliang, Wang Huitao, Zheng Anping, Sun Xiaodong, Wang Dong, Liu Haojia, Qin Yongpeng","doi":"10.13491/J.ISSN.1004-714X.2021.03.015","DOIUrl":"https://doi.org/10.13491/J.ISSN.1004-714X.2021.03.015","url":null,"abstract":"Objective The literature study the setup errors of head and neck, thoracic, abdominal and pelvic\u0000 tumors by megavoltage fan-beam CT based image guidance in TOMO-HD to provide the margin\u0000 enlarging from clinic target volume (CTV) to planning target volume (PTV) in treatment\u0000 planning system of TOMO-HD.\u0000 Methods 103 patients with head and neck (30 patients), thoracic (42 patients), abdominal\u0000 and pelvic (31 patients) carcinoma were enrolled. Megavoltage fan-beam CT based image\u0000 guidance in tomotherapy-HD was used to acquire CT scan before every treatment. The\u0000 left-right (X), superior-inferior (Y), anterior-posterior (Z) and rotation (Fy) setup\u0000 errors of patients can be obtained from the tomography image automatically restructured\u0000 by the system. Calculating the systematic error and the random error in the three\u0000 dimensions and check whether the setup data accord with the normal distribution or\u0000 not, then acquire the data expand in the three directions.\u0000 Results According to 2 593 fan-beam CT scans, the shift errors (µ ± s) in X, Y, Z and Fy\u0000 (rotation) of three study group were [(−0.31 ± 2.16) mm, (1.09 ± 3.56) mm, (2.36 ±\u0000 2.27) mm, (0.29 ± 0.96)°] (head and neck tumor), [(−0.98 ± 2.95) mm, (0.45 ± 6.86)\u0000 mm, (3.79 ± 2.47) mm, (0.18 ± 0.60)°] (thoracic cancer) and [(−0.86 ± 2.85) mm, (−1.59\u0000 ± 6.91) mm, (5.77 ± 2.40) mm, (0.20 ± 0.68)°] (abdominal and pelvic carcinoma). The\u0000 systematic errors (Σ) and random errors (σ) in X, Y, Z dimensions of patients with\u0000 head and neck, thoracic, abdominal and pelvic tumors were (1.06 mm and 1.84 mm), (1.93\u0000 mm and 3.43 mm), (2.41 mm and 2.71 mm), (1.10 mm and 2.56 mm), (3.79 mm and 5.46 mm),\u0000 (1.38 mm and 1.99 mm) and (1.39 mm and 0.87 mm), (4.98 mm and 5.69 mm), (1.19 mm and\u0000 2.05 mm), respectively.\u0000 Conclusion It is recommended as a reference for image guidance in TOMO-HD according to the frequency\u0000 distribution of setup errors, for patients with head and neck, chest and abdominal\u0000 and pelvic tumors, the maximum range of motion in three dimensions are (5.00, 5.00,\u0000 5.00) mm, (6,63, 17.25, 16.00) mm and (6.49, 16.24, 13.60) mm.\u0000 摘要： 目的 利用 TOMO-HD 螺旋加速器的 MV 级扇形束 CT 研宄头颈部、胸部、腹盆部肿瘤在放疗中的摆位误差, 为 PTV 边界的外扩提供数据支持。\u0000 方法 采用 TOMO-HD 螺旋断层系统分别对 30 例头颈部、42 例胸部和 31 例腹盆 部肿瘤患者每次放疗前行 MV 级扇形束 CT 扫描, 系统自动重建图像并与治疗计划\u0000 CT 图像进行配准, 获得患者左右 (X 轴)、头脚 (Y 轴)、腹背 (Z 轴)、沿Y轴方向的旋转 (Fy) 方向的摆位误差。计算出X、Y、Z方向的系统误差(Σ)\u0000 和随 机误差(σ)并对摆位误差进行正态性检验, 计算出 PTV 的各方向外扩边界。\u0000 结果 共行 2 593 次扫描, 头颈部、胸部、腹盆部患者在 X 轴、Y 轴、Z轴、Fy 方向 (沿 Y 轴方向的旋转) 的摆位误差 (µ ± s) 分别为 [(−0.31\u0000 ± 2.16)mm、(1.09 ± 3.56)mm、(2.36 ± 2.27)mm、(0.29 ± 0.96)°], [(−0.98 ± 2.95)mm、(−0.45\u0000 ± 6.86)mm、(3.79 ± 2.47)mm、(0.18 ± 0.60)°] 和 [(−0.86 ± 2.85)mm、(−1.59 ± 6.91)mm、(5.77\u0000 ± 2.40)mm、(0.20 ± 0.68)°]。头颈部、胸部、腹盆部患者在 X 轴、Y 轴、Z轴方向的系统误差(Σ)和随机误差(σ)分别为 (1.06 mm 和\u0000 1.84 mm)、(1.93 mm 和 3.43 mm)、(2.41 mm 和 2.71 mm)、(1.10 mm 和 2.56 mm)、(3.79 mm 和 5.46\u0000 mm)、(1.38 mm 和 1.99 mm) 和 (1.39 mm 和 0.87 mm)、(4.98 mm 和 5.69 mm)、(1.19 mm 和 2.05\u0000 mm)。\u0000 结论 根据不同部位的摆位误差频数分布, 头颈部、胸部、腹盆部不同 部位肿瘤患者的靶区在三维方向上最大运动范围参考值为 (5.00, 5.00, 5.00)mm,","PeriodicalId":58844,"journal":{"name":"中国辐射卫生","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44259828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.13491/J.ISSN.1004-714X.2021.03.016
Fan Xuemei, Hou Xin, L. Liang, XU Yumei, LI Liantao
Objective To compare the dosimetric difference of target and organs-at-risk between intensity-modulated radiotherapy (dIMRT) and volumetric modulated arc therapy (VMAT) for bilateral breast cancer, so as to discuss the clinical feasibility of radiotherapy for bilateral breast cancer. Methods The clinical data of 18 patients receiving radical or modified radical mastectomy for confirmed bilateral breast cancer were enrolled in this study. dIMRT plans and VMAT plans were designed for each patient, and discuss the dosimetric data of two radiotherapy plans. Results Both the two plans satisfied the prescription. In terms of the homogeneity index, VMAT plans (0.09 ± 0.02) were superior to dIMRT plans (0.11 ± 0.1, P < 0.05). In terms of the conformity index,VMAT plans (0.82 ± 0.52) were superior to dIMRT plans (0.71 ± 0,51, P < 0.05). Furthermore, VMAT plans (0.98 ± 0.06) were superior to dIMRT plans (1.24 ± 0.08, P < 0.05) in the dose gradient index. The V 10, V 20, V 30 and D mean of lungs in VMAT plans (39.07 ± 4.92, 22.19 ± 4.36, 12.81 ± 4.71, 1 309.03 ± 135.55) were higher than those in dIMRT plans (30.34 ± 4.26, 17.56 ± 4.31, 6.77 ± 3.93, 1 201.39 ± 166.77, P < 0.05). Meanwhile, the V 5 of lungs in VMAT plans (63.36 ± 9.02) was higher than that in dIMRT plans (58.01 ± 7.17, P > 0.05). However, the V 5, V 30 and D mean of heart in VMAT plans (51.98 ± 3.60, 3.78 ± 1.76, 885.89 ± 59.84) were lower than those in dIMRT plans (77.16 ± 12.11, 5.22 ± 2.85, 1 036.96 ± 151.46, P < 0.05). The D max of spinal cord in VMAT plans (2 150.42 ± 136.19) was significantly lower than that in dIMRT plans (3 008.23 ± 304.15, P < 0.05), Monitor units in VMAT plans (792.61 ± 62.53) was significantly lower than that in dIMRT plans (3 225.33 ± 498.66, P < 0.05). Conclusion Although VMAT has many advantages: achieves better homogeneity index and conformity index of target areas, reduces the irradiation dose of organs-at-risk, especially, the irradiation dose of heart and spinal cord is significantly reduced, however, it increases the irradiation dose of lungs. To reduce the recurrence of grade ≥ 2 radiation pneumonia, dIMRT should be better considered in the application of radiotherapy for bilateral breast cancer. 摘要： 目的 对比双侧乳腺癌术后放疗采用动态调强技术 (dIMRT) 和容积旋转调强技术 (VMAT) 时靶区和危及器官 的剂量学差异, 探索临床应用的可行性。 方法 选择 18 例双侧乳腺癌术后行全乳放疗的患者, 分别设计 dIMRT 和 VMAT 两组计划, 比较分析剂量学参数。 结果 两种治疗技术均能满足处方要求, 其中 VMAT 组的靶区均匀性指数 (0.09 ± 0.02) 优于 dIMRT 组 (0.11 ± 0.01), 适形度指数 (0.82 ± 0.52) 优于 dIMRT 组 (0.71 ± 0.51), 剂量梯度指数 (0.98 ± 0.06) 优于 dIMRT 组 (1.24 ± 0.08), 差异均具有统计学意义 ( P < 0.05); VMAT 组双肺的 V 10、 V 20、 V 30 和 D mean (39.07 ± 4.92, 22.19 ± 4.36, 12.81 ± 4.71, 1 309.03 ± 135.55) 均高于 dIMRT 组 (30.34 ± 4.26, 17.56 ± 4.31, 6.77 ± 3.93, 1 201.39 ± 166.77), 差异具有统计学意义 ( P < 0.05), VMAT 组双肺的 V 5 (63.36 ± 9.02) 高于 dIMRT (58.01 ± 7.17), 差异无统计学 意义 ( P > 0.05); VMAT 组心脏的 V 5、 V 30 和 D mean (51.98 ± 3.60, 3.78 ± 1.76, 885.89 ± 59.84) 均明显低于 dIMRT 组 (77.16 ± 12.11, 5.22 ± 2
Objective To compare the dosymetric difference of target and organs at risk between intensive modulated radiation (dIMRT) and volumetric modulated arc therapy (VMAT) for bilateral break cancer, so as to discuss the clinical feasibility of radiation for bilateral break cancer Methods The clinical data of 18 patients receiving radio or modified radio mast for confirmed bilateral breast cancer were enrolled in this study DIMRT plans and VMAT plans were designed for each patient, and discussed the dosymetric data of two radiapy plans Results Both the two plans satisfied the subscription In terms of the homogeneity index, VMAT plans (0.09 ± 0.02) were superior to dIMRT plans (0.11 ± 0.1, P<0.05) The V 10, V 20, V 30, and D mean of lungs in VMAT plans (39.07 ± 4.92, 22.19 ± 4.36, 12.81 ± 4.71, 1 309.03 ± 135.55) were higher than that in dIMRT plans (30.34 ± 4.26, 17.56 ± 4.31, 6.77 ± 3.93, 1 201.39 ± 166.77, P<0.05). Meanwhile, the V 5 of lungs in VMAT plans (63.36 ± 9.02) was higher than that in dIMRT plans (58.01 ± 7.17, P>0.05). However, the V 5, V 30 and D mean of heart in VMAT plans (51.98 ± 3.60, 3.78 ± 1.76, 885.89 ± 59.84) were lower than that in dIMRT plans (77.16 ± 12.11, 5.22 ± 2.85, 1 036.96 ± 151.46, P<0.05). The D max of spin core in VMAT plans (2 150.42 ± 136.19) was significantly lower than that in dIMRT plans (3 008.23 ± 304.15, P<0.05), Monitor units in VMAT plans (792.61 ± 62.53) were significantly lower than that in dIMRT plans (3 225.33 ± 498.66, P<0.05). UCED, HOWEVER, It increases the radiation dose of lungs To reduce the recurrence of grade ≥ 2 radiation pneumonia, dIMRT should be better considered in the application of radiation for bilateral break cancer Abstract: Objective To compare the dosimetry differences of target area and endangered organs in bilateral breast cancer postoperative radiotherapy using dynamic intensity modulation technology (dIMRT) and volume rotation intensity modulation technology (VMAT), and explore the feasibility of clinical application. Methods Eighteen patients with bilateral breast cancer who received whole breast radiotherapy after surgery were selected, and two groups of plans, dIMRT and VMAT, were designed respectively. Dosimetric parameters were compared and analyzed. The results showed that both treatment techniques were able to meet the prescription requirements, with the target area uniformity index (0.09 ± 0.02) in the VMAT group being better than that in the dIMRT group (0.11 ± 0.01), the fitness index (0.82 ± 0.52) being better than that in the dIMRT group (0.71 ± 0.51), and the dose gradient index (0.98 ± 0.06) being better than that in the dIMRT group (1.24 ± 0.08). The differences were statistically significant (P<0.05); The V 10, V 20, V 30, and D mean (39.07 ± 4.92, 22.19 ± 4.36, 12.81 ± 4.71, 1309.03 ± 135.55) in both lungs of the VMAT group were higher than those of the dIMRT group (30.34 ± 4.26, 17.56 ± 4.31, 6.77 ± 3.93, 1201.39 ± 166.77), with statistically significant differenc
{"title":"Dosimetric comparison between dIMRT and VMAT for bilateral breast cancer","authors":"Fan Xuemei, Hou Xin, L. Liang, XU Yumei, LI Liantao","doi":"10.13491/J.ISSN.1004-714X.2021.03.016","DOIUrl":"https://doi.org/10.13491/J.ISSN.1004-714X.2021.03.016","url":null,"abstract":"Objective To compare the dosimetric difference of target and organs-at-risk between intensity-modulated\u0000 radiotherapy (dIMRT) and volumetric modulated arc therapy (VMAT) for bilateral breast\u0000 cancer, so as to discuss the clinical feasibility of radiotherapy for bilateral breast\u0000 cancer.\u0000 Methods The clinical data of 18 patients receiving radical or modified radical mastectomy\u0000 for confirmed bilateral breast cancer were enrolled in this study. dIMRT plans and\u0000 VMAT plans were designed for each patient, and discuss the dosimetric data of two\u0000 radiotherapy plans.\u0000 Results Both the two plans satisfied the prescription. In terms of the homogeneity index,\u0000 VMAT plans (0.09 ± 0.02) were superior to dIMRT plans (0.11 ± 0.1, P < 0.05). In terms of the conformity index,VMAT plans (0.82 ± 0.52) were superior\u0000 to dIMRT plans (0.71 ± 0,51, P < 0.05). Furthermore, VMAT plans (0.98 ± 0.06) were superior to dIMRT plans (1.24\u0000 ± 0.08, P < 0.05) in the dose gradient index. The V\u0000 10, V\u0000 20, V\u0000 30 and D\u0000 mean of lungs in VMAT plans (39.07 ± 4.92, 22.19 ± 4.36, 12.81 ± 4.71, 1 309.03 ± 135.55)\u0000 were higher than those in dIMRT plans (30.34 ± 4.26, 17.56 ± 4.31, 6.77 ± 3.93, 1\u0000 201.39 ± 166.77, P < 0.05). Meanwhile, the V\u0000 5 of lungs in VMAT plans (63.36 ± 9.02) was higher than that in dIMRT plans (58.01\u0000 ± 7.17, P > 0.05). However, the V\u0000 5, V\u0000 30 and D\u0000 mean of heart in VMAT plans (51.98 ± 3.60, 3.78 ± 1.76, 885.89 ± 59.84) were lower than\u0000 those in dIMRT plans (77.16 ± 12.11, 5.22 ± 2.85, 1 036.96 ± 151.46, P < 0.05). The D\u0000 max of spinal cord in VMAT plans (2 150.42 ± 136.19) was significantly lower than that\u0000 in dIMRT plans (3 008.23 ± 304.15, P < 0.05), Monitor units in VMAT plans (792.61 ± 62.53) was significantly lower than\u0000 that in dIMRT plans (3 225.33 ± 498.66, P < 0.05).\u0000 Conclusion Although VMAT has many advantages: achieves better homogeneity index and conformity\u0000 index of target areas, reduces the irradiation dose of organs-at-risk, especially,\u0000 the irradiation dose of heart and spinal cord is significantly reduced, however, it\u0000 increases the irradiation dose of lungs. To reduce the recurrence of grade ≥ 2 radiation\u0000 pneumonia, dIMRT should be better considered in the application of radiotherapy for\u0000 bilateral breast cancer.\u0000 摘要： 目的 对比双侧乳腺癌术后放疗采用动态调强技术 (dIMRT) 和容积旋转调强技术 (VMAT) 时靶区和危及器官 的剂量学差异, 探索临床应用的可行性。\u0000 方法 选择 18 例双侧乳腺癌术后行全乳放疗的患者, 分别设计 dIMRT 和 VMAT 两组计划, 比较分析剂量学参数。\u0000 结果 两种治疗技术均能满足处方要求, 其中 VMAT 组的靶区均匀性指数 (0.09 ± 0.02) 优于 dIMRT 组 (0.11 ± 0.01), 适形度指数 (0.82\u0000 ± 0.52) 优于 dIMRT 组 (0.71 ± 0.51), 剂量梯度指数 (0.98 ± 0.06) 优于 dIMRT 组 (1.24 ± 0.08), 差异均具有统计学意义\u0000 (\u0000 P < 0.05); VMAT 组双肺的 V\u0000 10、\u0000 V\u0000 20、\u0000 V\u0000 30 和 D\u0000 mean (39.07 ± 4.92, 22.19 ± 4.36, 12.81 ± 4.71, 1 309.03 ± 135.55) 均高于 dIMRT 组 (30.34\u0000 ± 4.26, 17.56 ± 4.31, 6.77 ± 3.93, 1 201.39 ± 166.77), 差异具有统计学意义 (\u0000 P < 0.05), VMAT 组双肺的\u0000 V\u0000 5 (63.36 ± 9.02) 高于 dIMRT (58.01 ± 7.17), 差异无统计学 意义 (\u0000 P > 0.05); VMAT 组心脏的 V\u0000 5、\u0000 V\u0000 30 和 D\u0000 mean (51.98 ± 3.60, 3.78 ± 1.76, 885.89 ± 59.84) 均明显低于 dIMRT 组 (77.16 ± 12.11, 5.22 ±\u0000 2","PeriodicalId":58844,"journal":{"name":"中国辐射卫生","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44841257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.13491/J.ISSN.1004-714X.2021.03.020
Wan Jinbao, Zhao Hongfu
Brachytherapy plays an important role in radical radiotherapy of cervical cancer. At present, most hospitals in China use high-dose-ate brachytherapy, which irradiatevolume by simulating line source with a single approximate point source. Therefore, the dwell positions and dwell times can be optimized appropriately. However, due to various reasons, the initial state of the optimization plan must start from the standard loading pattern, and ensure that the optimized plan basically maintains the pear-shaped dose distribution. This paper introduces the standard loading pattern of intracavitary brachytherapy and intracavitary combined interstitial brachytherapy for cervical cancer through literature review, and expounds the planning optimization model and the constraints in the optimization process, to provide important reference for the planning of brachytherapy for cervical cancer. 摘要： 近距离放射治疗在宫颈癌的根治性放射治疗中有着重要的地位。目前, 国内绝大部分医院采用高剂量率近距 离治疗方式, 通过单一近似点源模拟线源来实现体积照射。因此, 驻留位置和驻留时间可以进行适当的优化。然而, 由 于种种原因优化计划的初始状态必须从标准载源模型开始, 并且保证优化后的计划基本保持梨形剂量分布。本文通 过文献综述介绍了宫颈癌腔内近距离治疗以及腔内联合组织间插植近距离治疗的标准载源模型, 并对计划优化模型 和优化过程中的限制条件等做适当阐述, 以期为宫颈癌近距离治疗计划设计提供重要参考。
{"title":"Progress of standard loading pattern of high-dose-rate brachytherapy in cervical cancer","authors":"Wan Jinbao, Zhao Hongfu","doi":"10.13491/J.ISSN.1004-714X.2021.03.020","DOIUrl":"https://doi.org/10.13491/J.ISSN.1004-714X.2021.03.020","url":null,"abstract":"Brachytherapy plays an important role in radical radiotherapy of cervical cancer.\u0000 At present, most hospitals in China use high-dose-ate brachytherapy, which irradiatevolume\u0000 by simulating line source with a single approximate point source. Therefore, the dwell\u0000 positions and dwell times can be optimized appropriately. However, due to various\u0000 reasons, the initial state of the optimization plan must start from the standard loading\u0000 pattern, and ensure that the optimized plan basically maintains the pear-shaped dose\u0000 distribution. This paper introduces the standard loading pattern of intracavitary\u0000 brachytherapy and intracavitary combined interstitial brachytherapy for cervical cancer\u0000 through literature review, and expounds the planning optimization model and the constraints\u0000 in the optimization process, to provide important reference for the planning of brachytherapy\u0000 for cervical cancer.\u0000 摘要： 近距离放射治疗在宫颈癌的根治性放射治疗中有着重要的地位。目前, 国内绝大部分医院采用高剂量率近距 离治疗方式, 通过单一近似点源模拟线源来实现体积照射。因此, 驻留位置和驻留时间可以进行适当的优化。然而,\u0000 由 于种种原因优化计划的初始状态必须从标准载源模型开始, 并且保证优化后的计划基本保持梨形剂量分布。本文通 过文献综述介绍了宫颈癌腔内近距离治疗以及腔内联合组织间插植近距离治疗的标准载源模型,\u0000 并对计划优化模型 和优化过程中的限制条件等做适当阐述, 以期为宫颈癌近距离治疗计划设计提供重要参考。","PeriodicalId":58844,"journal":{"name":"中国辐射卫生","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43818057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.13491/J.ISSN.1004-714X.2021.03.006
Wu Zhe, Wang Dong, C. Xiaomei, M. Zhi, Liu Ke, Yan Jun
Objective This study aims to compare the advantages and disadvantages of the three techniques in improving the target volume dose and protecting the auris media cavity and eustachian tube isthmus region by investigating the dosimetric differences of three whole-brain radiotherapy techniques. Methods Thirty patients with whole brain metastases were randomly selected to design fixed field intensity modulated radiotherapy (ff-IMRT) plan, volumetric arc modulated therapy (VMAT) and three-dimensional conformai radiotherapy (3DCRT) plan, and to meet a 95% PTV prescription dose (40 Gy). The dosimetric parameters and monitor units of the target volume and organ at risk (OAR) in the three groups of treatment plans were compared and analyzed. Results The Conformity Index ( CI) of the ff-IMRT plan (0.93 ± 0.02) was better than the VMAT plan (0.89 ± 0.01) and the 3DCRT plan (0.73 ± 0.03), respectively, and the difference was statistically significant ( P < 0.05). The Homogeneity Index ( HI) of the three plans were ff-IMRT (0.05 ± 0,01)、VMAT (0.08 ± 0.1) and 3DCRT (0.08 ± 0.01), respectively, and the difference was not statistically significant ( P > 0.05). The Gradient Index ( GT) were ff-IMRT (1.77 ± 0.1), VMAT (1.61 ± 0.07), 3DCRT (1.39 ± 0.08), respectively. The difference was statistically significant ( P< 0.05). The monitor units (MU) were ff-IMRT (1 551.97 ± 85.02), VMAT (303.7 ± 24.28) and 3DCRT (226.2 ± 2.5), respectively, the difference was statistically significant ( P < 0.05). The D max of the middle ear of the three plans were ff-IMRT (2 557.54 ± 477.39) cGy, VMAT (3 107.9 ± 362.28) cGy, 3DCRT (4 055.37 ± 71.45) cGy, respectively. The D max of the eustachian tube isthmus were ff-IMRT (2 425 ± 380.4) cGy, VMAT (2 902.4 ± 526.3) cGy and 3DCRT (3 862.7 ± 135.9) cGy, the difference were statistically significant ( P < 0.05). Conclusion In whole-brain radiotherapy, ff-IMRT and VMAT significantly reduced fhe dose of fhe bilateral middle ear cavities and eustachian tube isthmus compared with 3DCRT. VMAT is recommended for WBRT for reducing the number of monitor units significantly. 摘要： 目的 比较脑转移瘤全脑放射治疗 (WBRT)3 种放疗技术对中耳的剂量学差异, 对比 3 种放疗技术在改善靶区 剂量和保护中耳腔和咽鼓管峡部的优劣势。 方法 选取 2018 年 7 月 1 日一2019 年 8 月 1 日我院收治的 30 例脑转移 瘤患者, 分别设计固定野调强放疗 (ff-IMRT) 计划、容积旋转调强放疗 (VMAT) 和三维适形放疗 (3DCRT) 计划, 要求处 方剂量 (40 Gy) 覆盖 95% 的计划靶区 (PTV)。对比分析 3 组计划的靶区和危及器官剂量学参数、机器跳数等差异。 结果 ff-IMRT 计划的适形指数 (0.93 ± 0.02) 优于VMAT计划 (0.89 ± 0.01) 和 3DCRT 计划 (0.73 ± 0.03), 差异有统计 学意义 ( P < 0.05); ff-IMRT、VMAT 和 3DCRT 3 种计划的均匀指数分别为 (0.05 ± 0.01)、(0.08 ± 0.1)、(0.08 ± 0.01), 差异无统计学意义 ( P > 0.05); 梯度指数分别为 (1.77 ± 0.1)、(1.61 ± 0.07)、(1.39 ± 0.08), 差异有统计学意义 ( P < 0.05); 机器跳数分别为 (1 551.97 ± 85.05)、(303.7 ± 24.28)、(226.2 ± 2.5), 差异有统计学意义 ( P < 0.05)。ff-IMRT、VMAT 和 3DCRT 3 种计划中耳腔最大剂量点 ( D max) 分别为 ff-IMRT (2 557.54 ± 477.39) cGy、VMAT (3 107.9 ± 362.28) cGy、3DCRT (4 055.37 ± 71.45) cGy; 咽鼓管峡部 D max 分别为 ff-IMRT (2 425 ± 380.4) cGy、VMAT (2 902.4 ± 526.3) cGy、3DCRT (3 862.7
{"title":"Dosimetric study on middle ear with three whole-brain radiotherapy techniques","authors":"Wu Zhe, Wang Dong, C. Xiaomei, M. Zhi, Liu Ke, Yan Jun","doi":"10.13491/J.ISSN.1004-714X.2021.03.006","DOIUrl":"https://doi.org/10.13491/J.ISSN.1004-714X.2021.03.006","url":null,"abstract":"Objective This study aims to compare the advantages and disadvantages of the three techniques\u0000 in improving the target volume dose and protecting the auris media cavity and eustachian\u0000 tube isthmus region by investigating the dosimetric differences of three whole-brain\u0000 radiotherapy techniques.\u0000 Methods Thirty patients with whole brain metastases were randomly selected to design fixed\u0000 field intensity modulated radiotherapy (ff-IMRT) plan, volumetric arc modulated therapy\u0000 (VMAT) and three-dimensional conformai radiotherapy (3DCRT) plan, and to meet a 95%\u0000 PTV prescription dose (40 Gy). The dosimetric parameters and monitor units of the\u0000 target volume and organ at risk (OAR) in the three groups of treatment plans were\u0000 compared and analyzed.\u0000 Results The Conformity Index (\u0000 CI) of the ff-IMRT plan (0.93 ± 0.02) was better than the VMAT plan (0.89 ± 0.01) and\u0000 the 3DCRT plan (0.73 ± 0.03), respectively, and the difference was statistically significant\u0000 (\u0000 P < 0.05). The Homogeneity Index (\u0000 HI) of the three plans were ff-IMRT (0.05 ± 0,01)、VMAT (0.08 ± 0.1) and 3DCRT (0.08\u0000 ± 0.01), respectively, and the difference was not statistically significant (\u0000 P > 0.05). The Gradient Index (\u0000 GT) were ff-IMRT (1.77 ± 0.1), VMAT (1.61 ± 0.07), 3DCRT (1.39 ± 0.08), respectively.\u0000 The difference was statistically significant (\u0000 P< 0.05). The monitor units (MU) were ff-IMRT (1 551.97 ± 85.02), VMAT (303.7 ± 24.28)\u0000 and 3DCRT (226.2 ± 2.5), respectively, the difference was statistically significant\u0000 (\u0000 P < 0.05). The D\u0000 max of the middle ear of the three plans were ff-IMRT (2 557.54 ± 477.39) cGy, VMAT (3\u0000 107.9 ± 362.28) cGy, 3DCRT (4 055.37 ± 71.45) cGy, respectively. The D\u0000 max of the eustachian tube isthmus were ff-IMRT (2 425 ± 380.4) cGy, VMAT (2 902.4 ±\u0000 526.3) cGy and 3DCRT (3 862.7 ± 135.9) cGy, the difference were statistically significant\u0000 (\u0000 P < 0.05).\u0000 Conclusion In whole-brain radiotherapy, ff-IMRT and VMAT significantly reduced fhe dose of fhe\u0000 bilateral middle ear cavities and eustachian tube isthmus compared with 3DCRT. VMAT\u0000 is recommended for WBRT for reducing the number of monitor units significantly.\u0000 摘要： 目的 比较脑转移瘤全脑放射治疗 (WBRT)3 种放疗技术对中耳的剂量学差异, 对比 3 种放疗技术在改善靶区 剂量和保护中耳腔和咽鼓管峡部的优劣势。\u0000 方法 选取 2018 年 7 月 1 日一2019 年 8 月 1 日我院收治的 30 例脑转移 瘤患者, 分别设计固定野调强放疗 (ff-IMRT) 计划、容积旋转调强放疗\u0000 (VMAT) 和三维适形放疗 (3DCRT) 计划, 要求处 方剂量 (40 Gy) 覆盖 95% 的计划靶区 (PTV)。对比分析 3 组计划的靶区和危及器官剂量学参数、机器跳数等差异。\u0000 结果 ff-IMRT 计划的适形指数 (0.93 ± 0.02) 优于VMAT计划 (0.89 ± 0.01) 和 3DCRT 计划 (0.73 ± 0.03), 差异有统计\u0000 学意义 (\u0000 P < 0.05); ff-IMRT、VMAT 和 3DCRT 3 种计划的均匀指数分别为 (0.05 ± 0.01)、(0.08 ± 0.1)、(0.08 ± 0.01),\u0000 差异无统计学意义 (\u0000 P > 0.05); 梯度指数分别为 (1.77 ± 0.1)、(1.61 ± 0.07)、(1.39 ± 0.08), 差异有统计学意义 (\u0000 P < 0.05); 机器跳数分别为 (1 551.97 ± 85.05)、(303.7 ± 24.28)、(226.2 ± 2.5), 差异有统计学意义 (\u0000 P < 0.05)。ff-IMRT、VMAT 和 3DCRT 3 种计划中耳腔最大剂量点 (\u0000 D\u0000 max) 分别为 ff-IMRT (2 557.54 ± 477.39) cGy、VMAT (3 107.9 ± 362.28) cGy、3DCRT (4 055.37\u0000 ± 71.45) cGy; 咽鼓管峡部 D\u0000 max 分别为 ff-IMRT (2 425 ± 380.4) cGy、VMAT (2 902.4 ± 526.3) cGy、3DCRT (3 862.7 ","PeriodicalId":58844,"journal":{"name":"中国辐射卫生","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46809570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.13491/J.ISSN.1004-714X.2021.03.011
Ni Jie, Z. Juying, Zhan Wei, Guo Jian, Chen Long, Gan Guanghui, Xu Yueliang, Liao Yiqiu
Objective To effectively use the clinical data generated in daily operation and to realize information networking based on the existing resources of radiotherapy department. To improve quality management efficiency in radiotherapy process. Methods The radiotherapy process and required documents were analyzed. The reporting tool Microsoft Report Builder, which is based on SQL database, was applied to design the patient documents by extracting and analyzing a large number of data generated by Aria, the existing network of our radiotherapy department. PDCA Tools was used to analyze the weak links in the process. Reports with quantitative indices have been designed according to corresponding countermeasures, so as to improve quality control level of the process. Results More than one thousand patients were treated in our department since 2020. All patient documents of radiotherapy can be archived and inquired online after registration only once. 13 daily statistical reports, 5 quarters and 3 annual reports were scheduled according to practical demands. The waiting time before radiotherapy was shortened from 16.2 days to 14.8 days after operating the reporting system 3 months later. The staff could master the treatment progress of patients easily and patients who interrupted the treatment were found in time. Conclusion The reporting tools can realize patient information extraction and networked management effectively in radiotherapy process. Staff efficiency of personnel work and communication was improved. The resource allocation was optimized according to the report data in real time, improving the efficiency and quality of radiotherapy. This method is generally applicable and practical to radiotherapy department. 摘要： 目的 有效利用放疗科日常运行中产生的临床数据, 基于科室已有网络资源实现放疗信息无纸化, 提高放疗流 程质控水平。 方法 分析科室放疗流程及所需文档, 运用基于 SQL 数据库的报表工具 Report Builder, 对放疗科已有 网络 Aria 产生的大量数据进行提取和分析, 开发报表实现患者现有放疗文档的电子化;运用 PDCA 的方法分析流程 中存在的薄弱环节, 提出对策并设计相应报表量化指标,从而提高流程质控水平。 结果 自 2020 年全面实施以来, 科 室实施放疗两千余人次, 患者放疗信息一次登记后全部文档实现网络存档和查询。根据实际工作需求制定了 13 个日 常统计报表、5 个季度和 3 个年度统计报表, 通过报表统计使用报表前后 3 个月的放疗前等待时间由 16.2 d 缩短至 14.8 d, 工作人员能够掌握患者治疗进度, 及时发现 12 例中断治疗的患者。 结论 通过报表工具的信息提取能够实现 放疗全流程信息网络化和患者放疗数据电子化, 提高了人员工作效率和沟通效率,科室能够根据报表数据实时优化资 源配置, 提高放疗的效率和质量。该方法具有普适性和实用性。
Objective To effectively use the clinical data generated in daily operation and to achieve information networking based on the existing resources of radiology department To improve quality management effectiveness in radiometry processes Methods The radiology process and required documents were analyzed The reporting tool Microsoft Report Builder, which is based on SQL database, was applied to design the patient documents by extracting and analyzing a large number of data generated by Aria, the existing network of our radiology department PDCA Tools was used to analyze the weak links in the process Reports with quantitative indicators have been designed according to corresponding counter measures, so as to improve quality control level of the process Results More than one thought and patients were treated in our department since 2020 All patient documents of radiology can be archived and required online after registration only once 13 daily statistical reports, 5 quarters, and 3 annual reports were scheduled according to practical demands The waiting time before radiotherapy was shortened from 16.2 days to 14.8 days after operating the reporting system 3 months later The staff could master the treatment progress of patients easily and patients who interrupted the treatment were found in time Conclusion The reporting tools can achieve patient information extraction and networked management effectively in radiapy processes Staff efficiency of personnel work and communication was improved The resource allocation was optimized according to the report data in real time, improving the efficiency and quality of radiation This method is generally applicable and practical to radiology department Abstract: Objective: To effectively utilize the clinical data generated in the daily operation of the radiotherapy department, based on the existing network resources of the department, to achieve paperless radiotherapy information and improve the quality control level of the radiotherapy process. Method: Analyze the radiotherapy process and required documents in the department, use the SQL database based report tool Report Builder to extract and analyze a large amount of data generated by the existing network Aria in the radiotherapy department, and develop reports to achieve the digitization of existing radiotherapy documents for patients; Using the PDCA method to analyze the weak links in the process, propose countermeasures, and design corresponding report quantification indicators to improve the quality control level of the process. Since its comprehensive implementation in 2020, the department has implemented radiotherapy for over 2000 people, and all patient radiotherapy information has been registered once, and all documents have been archived and queried online. Based on actual work needs, 13 daily statistical reports, 5 quarterly reports, and 3 annual statistical reports were developed. The waiting time before and after radiotherapy for 3 months before a
{"title":"Development of SQL-based reporting tools and its application in radiotherapy workflow quality management","authors":"Ni Jie, Z. Juying, Zhan Wei, Guo Jian, Chen Long, Gan Guanghui, Xu Yueliang, Liao Yiqiu","doi":"10.13491/J.ISSN.1004-714X.2021.03.011","DOIUrl":"https://doi.org/10.13491/J.ISSN.1004-714X.2021.03.011","url":null,"abstract":"Objective To effectively use the clinical data generated in daily operation and to realize\u0000 information networking based on the existing resources of radiotherapy department.\u0000 To improve quality management efficiency in radiotherapy process.\u0000 Methods The radiotherapy process and required documents were analyzed. The reporting tool\u0000 Microsoft Report Builder, which is based on SQL database, was applied to design the\u0000 patient documents by extracting and analyzing a large number of data generated by\u0000 Aria, the existing network of our radiotherapy department. PDCA Tools was used to\u0000 analyze the weak links in the process. Reports with quantitative indices have been\u0000 designed according to corresponding countermeasures, so as to improve quality control\u0000 level of the process.\u0000 Results More than one thousand patients were treated in our department since 2020. All patient\u0000 documents of radiotherapy can be archived and inquired online after registration only\u0000 once. 13 daily statistical reports, 5 quarters and 3 annual reports were scheduled\u0000 according to practical demands. The waiting time before radiotherapy was shortened\u0000 from 16.2 days to 14.8 days after operating the reporting system 3 months later. The\u0000 staff could master the treatment progress of patients easily and patients who interrupted\u0000 the treatment were found in time.\u0000 Conclusion The reporting tools can realize patient information extraction and networked management\u0000 effectively in radiotherapy process. Staff efficiency of personnel work and communication\u0000 was improved. The resource allocation was optimized according to the report data in\u0000 real time, improving the efficiency and quality of radiotherapy. This method is generally\u0000 applicable and practical to radiotherapy department.\u0000 摘要： 目的 有效利用放疗科日常运行中产生的临床数据, 基于科室已有网络资源实现放疗信息无纸化, 提高放疗流 程质控水平。\u0000 方法 分析科室放疗流程及所需文档, 运用基于 SQL 数据库的报表工具 Report Builder, 对放疗科已有 网络 Aria 产生的大量数据进行提取和分析, 开发报表实现患者现有放疗文档的电子化;运用\u0000 PDCA 的方法分析流程 中存在的薄弱环节, 提出对策并设计相应报表量化指标,从而提高流程质控水平。\u0000 结果 自 2020 年全面实施以来, 科 室实施放疗两千余人次, 患者放疗信息一次登记后全部文档实现网络存档和查询。根据实际工作需求制定了 13 个日 常统计报表、5\u0000 个季度和 3 个年度统计报表, 通过报表统计使用报表前后 3 个月的放疗前等待时间由 16.2 d 缩短至 14.8 d, 工作人员能够掌握患者治疗进度, 及时发现\u0000 12 例中断治疗的患者。\u0000 结论 通过报表工具的信息提取能够实现 放疗全流程信息网络化和患者放疗数据电子化, 提高了人员工作效率和沟通效率,科室能够根据报表数据实时优化资 源配置, 提高放疗的效率和质量。该方法具有普适性和实用性。","PeriodicalId":58844,"journal":{"name":"中国辐射卫生","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46375261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.13491/J.ISSN.1004-714X.2021.03.024
Wang Jing, Zhou Fang
As is known, the nuclear accident resulting from the explosion of a nuclear weapon or the release of nuclear material could cause acute radiation syndrome within a short time. The study had found that the dose of > 0.7 Gy radiation on human body can result in persistent myelosuppression, a kind of acute radiation syndrome, leading to pancytopenia, bleeding, infection and other injuries. Several evidences also have shown that hematopoietic stem cell is conducive to repair hematopoietic injury in bone marrow, improve hematopoietic microenvironment and promote hematopoietic reconstruction. Therefore, hematopoietic stem cell transplantation is widely considered as the main treatment of the bone marrow acute radiation syndrome. However, before a surgery of hematopoietic stem cell transplantation, it still needs more research on donor selection, formulation of preconditioning and prevention of complications such as grafl-versus-host disease. This paper mainly summarizes the application and research progress of hematopoietic stem cell transplantation in treating radiation injury. 摘要： 核武器爆炸或核物质泄漏导致的核事故, 短时间内会造成急性放射病。人体接受剂量 >0.7 Gy 辐射可导致骨 髓持久抑制即急性放射病, 引起全血细胞减少、出血、感染等损伤。大量研宄显示, 造血干细胞移植是治疗骨髓型急性 放射性疾病的主要手段。造血干细胞可以修复骨髓造血损伤, 改善造血微环境, 促进造血重建。在使用造血干细胞移 植术前选择供者、制定预处理方案及预防移植物抗宿主病等并发症的方案仍需要研宄, 本文主要概述了造血干细胞移 植在辐射损伤中的应用及研宄进展。
As is known, the nuclear accident resulting from the exploration of a nuclear weapon or the release of nuclear material could cause acute radiation syndrome within a short time The study had found that the dose of>0.7 Gy radiation on human body can result in persistent myelosupression, a kind of acute radiation syndrome, leading to pancytopia, bleeding, infection and other injuries Several opinions also have shown that homeopathic stem cells are conductive to repair homeopathic injury in bone row, improve homeopathic microenvironment and promote homeopathic reconstruction Theoretical, hematological stem cell transplantation is widely considered as the main treatment of the bone marrow acute radiation syndrome How, before a large sum of hematological stem cell transmission, it still needs more research on donor selection, formulation of preconditioning and prevention of complications such as grafl Versus host disease This paper mainly summarizes the application and research progress of hematological stem cell transplantation in treating radiation injury Abstract: Nuclear accidents caused by nuclear weapon explosions or nuclear material leaks can cause acute radiation sickness in a short period of time. The human body can receive radiation with a dose greater than 0.7 Gy, which can lead to persistent bone marrow suppression, namely acute radiation sickness, causing damage such as whole blood cell reduction, bleeding, and infection. Numerous studies have shown that hematopoietic stem cell transplantation is the main method for treating acute radiation sickness of bone marrow type. Hematopoietic stem cells can repair bone marrow hematopoietic damage, improve the hematopoietic microenvironment, and promote hematopoietic reconstruction. There is still a need to study the selection of donors, formulation of pre-treatment plans, and prevention of complications such as graft versus host disease before using hematopoietic stem cell transplantation. This article mainly outlines the application and research progress of hematopoietic stem cell transplantation in radiation damage.
{"title":"Research progress in hematopoietic stem cell transplantation for bone marrow acute radiation syndrome","authors":"Wang Jing, Zhou Fang","doi":"10.13491/J.ISSN.1004-714X.2021.03.024","DOIUrl":"https://doi.org/10.13491/J.ISSN.1004-714X.2021.03.024","url":null,"abstract":"As is known, the nuclear accident resulting from the explosion of a nuclear weapon\u0000 or the release of nuclear material could cause acute radiation syndrome within a short\u0000 time. The study had found that the dose of > 0.7 Gy radiation on human body can result\u0000 in persistent myelosuppression, a kind of acute radiation syndrome, leading to pancytopenia,\u0000 bleeding, infection and other injuries. Several evidences also have shown that hematopoietic\u0000 stem cell is conducive to repair hematopoietic injury in bone marrow, improve hematopoietic\u0000 microenvironment and promote hematopoietic reconstruction. Therefore, hematopoietic\u0000 stem cell transplantation is widely considered as the main treatment of the bone marrow\u0000 acute radiation syndrome. However, before a surgery of hematopoietic stem cell transplantation,\u0000 it still needs more research on donor selection, formulation of preconditioning and\u0000 prevention of complications such as grafl-versus-host disease. This paper mainly summarizes\u0000 the application and research progress of hematopoietic stem cell transplantation in\u0000 treating radiation injury.\u0000 摘要： 核武器爆炸或核物质泄漏导致的核事故, 短时间内会造成急性放射病。人体接受剂量 >0.7 Gy 辐射可导致骨 髓持久抑制即急性放射病, 引起全血细胞减少、出血、感染等损伤。大量研宄显示,\u0000 造血干细胞移植是治疗骨髓型急性 放射性疾病的主要手段。造血干细胞可以修复骨髓造血损伤, 改善造血微环境, 促进造血重建。在使用造血干细胞移 植术前选择供者、制定预处理方案及预防移植物抗宿主病等并发症的方案仍需要研宄,\u0000 本文主要概述了造血干细胞移 植在辐射损伤中的应用及研宄进展。","PeriodicalId":58844,"journal":{"name":"中国辐射卫生","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46704291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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