Pub Date : 1955-05-01DOI: 10.1001/ARCHPEDI.1955.02050110639001
C. Daeschner, J. Clark, G. George, R. Frankel
Vomiting is both a common and an important therapeutic problem in children. Every physician is aware of the extreme dehydration that may quickly follow its onset. A drug which appears to be a safe and effective agent for the control of vomiting is now available in the form of chlorpromazine hydrochloride* (10-[γ-dimethylaminopropyl]-2-chlorophenothiazine hydrochloride). Boyd and co-workers † and Cook and Toner 3 have shown that this drug inhibits apomorphine-induced emesis in animals. These studies suggest that chlorpromazine acts by depressing the vomiting center within the central nervous system, thus blocking the vomiting reflex. Several forms of side-reaction have been described in connection with chlorpromazine therapy. A sedative effect of variable degree is seen in the majority of successfully treated patients. This effect is most pronounced after the first dose and usually disappears within a few hours. Pharmacological studies by Moyer and co-workers 4 reveal that in the usually administered therapeutic
{"title":"Chlorpromazine in the control of vomiting in children; preliminary clinical evaluation.","authors":"C. Daeschner, J. Clark, G. George, R. Frankel","doi":"10.1001/ARCHPEDI.1955.02050110639001","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1955.02050110639001","url":null,"abstract":"Vomiting is both a common and an important therapeutic problem in children. Every physician is aware of the extreme dehydration that may quickly follow its onset. A drug which appears to be a safe and effective agent for the control of vomiting is now available in the form of chlorpromazine hydrochloride* (10-[γ-dimethylaminopropyl]-2-chlorophenothiazine hydrochloride). Boyd and co-workers † and Cook and Toner 3 have shown that this drug inhibits apomorphine-induced emesis in animals. These studies suggest that chlorpromazine acts by depressing the vomiting center within the central nervous system, thus blocking the vomiting reflex. Several forms of side-reaction have been described in connection with chlorpromazine therapy. A sedative effect of variable degree is seen in the majority of successfully treated patients. This effect is most pronounced after the first dose and usually disappears within a few hours. Pharmacological studies by Moyer and co-workers 4 reveal that in the usually administered therapeutic","PeriodicalId":6798,"journal":{"name":"A.M.A. American journal of diseases of children","volume":"21 1","pages":"525-30"},"PeriodicalIF":0.0,"publicationDate":"1955-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91192269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1955-05-01DOI: 10.1001/archpedi.1955.02050110716014
L J FLAX, I GERSH
{"title":"Congenital renal tubular dysfunction (nephrogenic diabetes insipidus); report of a case complicated by calcifications in the renal pedicle.","authors":"L J FLAX, I GERSH","doi":"10.1001/archpedi.1955.02050110716014","DOIUrl":"https://doi.org/10.1001/archpedi.1955.02050110716014","url":null,"abstract":"","PeriodicalId":6798,"journal":{"name":"A.M.A. American journal of diseases of children","volume":"89 5","pages":"602-5"},"PeriodicalIF":0.0,"publicationDate":"1955-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1955.02050110716014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23880996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chlorpromazine in the control of vomiting in children; preliminary clinical evaluation.","authors":"C W DAESCHNER, J L CLARK, G Y GEORGE, R A FRANKEL","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":6798,"journal":{"name":"A.M.A. American journal of diseases of children","volume":"89 5","pages":"525-30"},"PeriodicalIF":0.0,"publicationDate":"1955-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23880983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1955-05-01DOI: 10.1001/archpedi.1955.02050110653003
B K SILVERMAN, T BRECKX, J CRAIG, A S NADAS
{"title":"Congestive failure in the newborn caused by cerebral A-V fistula; a clinical and pathological report of two cases.","authors":"B K SILVERMAN, T BRECKX, J CRAIG, A S NADAS","doi":"10.1001/archpedi.1955.02050110653003","DOIUrl":"https://doi.org/10.1001/archpedi.1955.02050110653003","url":null,"abstract":"","PeriodicalId":6798,"journal":{"name":"A.M.A. American journal of diseases of children","volume":"89 5","pages":"539-43"},"PeriodicalIF":0.0,"publicationDate":"1955-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1955.02050110653003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23880985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1955-05-01DOI: 10.1001/archpedi.1955.02050110686008
W A REILLY, K G SCOTT, R W WINTERS, H L HELWIG
{"title":"Anionic resin measurement of protein-bound I131 in euthyroid children.","authors":"W A REILLY, K G SCOTT, R W WINTERS, H L HELWIG","doi":"10.1001/archpedi.1955.02050110686008","DOIUrl":"https://doi.org/10.1001/archpedi.1955.02050110686008","url":null,"abstract":"","PeriodicalId":6798,"journal":{"name":"A.M.A. American journal of diseases of children","volume":"89 5","pages":"572-4"},"PeriodicalIF":0.0,"publicationDate":"1955-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1955.02050110686008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23880990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1955-05-01DOI: 10.1001/archpedi.1955.02050110705011
T E REICHELDERFER, J VAN HARTESVELDT
{"title":"Intravenous cholecystography with cholografin in infants.","authors":"T E REICHELDERFER, J VAN HARTESVELDT","doi":"10.1001/archpedi.1955.02050110705011","DOIUrl":"https://doi.org/10.1001/archpedi.1955.02050110705011","url":null,"abstract":"","PeriodicalId":6798,"journal":{"name":"A.M.A. American journal of diseases of children","volume":"89 5","pages":"591-5"},"PeriodicalIF":0.0,"publicationDate":"1955-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1955.02050110705011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23880993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Serum pigment studies in newborn infants. I. Erythroblastosis fetalis.","authors":"A H TUTTLE","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":6798,"journal":{"name":"A.M.A. American journal of diseases of children","volume":"89 5","pages":"544-52"},"PeriodicalIF":0.0,"publicationDate":"1955-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23880986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1955-05-01DOI: 10.1001/archpedi.1955.02050110720016
E F HOCK, E M JONES
{"title":"Aneurysm of the renal artery causing hypertension.","authors":"E F HOCK, E M JONES","doi":"10.1001/archpedi.1955.02050110720016","DOIUrl":"https://doi.org/10.1001/archpedi.1955.02050110720016","url":null,"abstract":"","PeriodicalId":6798,"journal":{"name":"A.M.A. American journal of diseases of children","volume":"89 5","pages":"606-8"},"PeriodicalIF":0.0,"publicationDate":"1955-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1955.02050110720016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23880997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1955-05-01DOI: 10.1001/archpedi.1955.02050110729021
J J BOCIAN, M LIANG
POLYCYSTIC disease of the kidney is relatively uncommon in children. It is generally believed that the cysts are due to a failure of union between the secretory and collecting portions of the kidney unit. Polycystic disease of the kidney is mostly bilateral, but unilateral involvement has been reported. Bell has expressed the opinion that polycystic kidneys are inherited as a Mendelian dominant. Cairns and others list the defects with which it is most frequently associated, such as harelip, spina bifida, atresia ani, and defects of kdneys, ureters, and sex organs. Rall and Odel have found associated congenital anomalies encountered in polycystic disease of the kidneys, as polycystic liver, polycystic pancreas, polycystic spleen, cardiac defects, defects of nervous system, and defects of musculoskeletal system. Potter classifies the polycystic kidneys found in the fetus or young infant into two groups: (1) those in which the amount of renal connective tissue is normal
{"title":"Rare case of polycystic disease of the kidneys.","authors":"J J BOCIAN, M LIANG","doi":"10.1001/archpedi.1955.02050110729021","DOIUrl":"https://doi.org/10.1001/archpedi.1955.02050110729021","url":null,"abstract":"POLYCYSTIC disease of the kidney is relatively uncommon in children. It is generally believed that the cysts are due to a failure of union between the secretory and collecting portions of the kidney unit. Polycystic disease of the kidney is mostly bilateral, but unilateral involvement has been reported. Bell has expressed the opinion that polycystic kidneys are inherited as a Mendelian dominant. Cairns and others list the defects with which it is most frequently associated, such as harelip, spina bifida, atresia ani, and defects of kdneys, ureters, and sex organs. Rall and Odel have found associated congenital anomalies encountered in polycystic disease of the kidneys, as polycystic liver, polycystic pancreas, polycystic spleen, cardiac defects, defects of nervous system, and defects of musculoskeletal system. Potter classifies the polycystic kidneys found in the fetus or young infant into two groups: (1) those in which the amount of renal connective tissue is normal","PeriodicalId":6798,"journal":{"name":"A.M.A. American journal of diseases of children","volume":"89 5","pages":"615-7"},"PeriodicalIF":0.0,"publicationDate":"1955-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1955.02050110729021","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23881000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1955-05-01DOI: 10.1001/archpedi.1955.02050110645002
J M SINGER, J BAR-HAY, R HOENIGSBERG
{"title":"The intestinal flora in the etiology of infantile infectious diarrhea.","authors":"J M SINGER, J BAR-HAY, R HOENIGSBERG","doi":"10.1001/archpedi.1955.02050110645002","DOIUrl":"https://doi.org/10.1001/archpedi.1955.02050110645002","url":null,"abstract":"","PeriodicalId":6798,"journal":{"name":"A.M.A. American journal of diseases of children","volume":"89 5","pages":"531-8"},"PeriodicalIF":0.0,"publicationDate":"1955-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1955.02050110645002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23880984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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