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Pilot kinematic study of swallowing in healthy adults: age-related, individualised, and lateralised patterns of bolus trajectories. 健康成人吞咽的初步运动学研究:与年龄相关的,个体化的,以及丸轨迹的横向模式。
IF 1 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-01 Epub Date: 2025-10-18 DOI: 10.1080/00016489.2025.2572973
Nobuyuki Arai, Takashi Hiraoka, Kozo Hanayama

Background: Swallowing function may undergo subtle changes with age, even in asymptomatic adults. However, objective and reproducible metrics for characterising normal swallowing motion remain limited.

Aims/objectives: This pilot study aimed to quantify the spatiotemporal trajectory of the bolus centre of mass (CoM) during swallowing in healthy adults and explore its potential as a kinematic marker for identifying individualised and age-associated patterns.

Materials and methods: Thirteen healthy adults (aged 26-62 years) underwent videofluoroscopic swallowing studies using contrast-enhanced liquid boluses. Bolus CoMs were tracked throughout the oropharyngeal phase. Multiple swallows per participant were analysed to assess intra-individual consistency. K-means clustering and silhouette analysis were applied to the CoM trajectory data to evaluate pattern reproducibility and explore potential age-related differences.

Results: CoM trajectories were highly consistent within individuals (silhouette score = 0.718). Clustering revealed age-related patterns: older participants exhibited more centralised trajectories, whereas younger participants demonstrated more lateralised movement. Additional differences in bolus descent and pharyngeal coordination existed between age groups.

Conclusions and significance: Bolus CoM trajectory analysis is a feasible and reproducible approach for assessing swallowing kinematics. These trajectories may represent individualised motor signatures and could help identify subtle, age-related changes. The findings underscore the need for personalised dysphagia assessment and rehabilitation strategies.

背景:吞咽功能可能随着年龄的增长而发生微妙的变化,即使在无症状的成年人中也是如此。然而,表征正常吞咽运动的客观和可重复的指标仍然有限。目的/目的:本初步研究旨在量化健康成人吞咽过程中丸质量中心(CoM)的时空轨迹,并探索其作为识别个体化和年龄相关模式的运动学标记的潜力。材料和方法:13名健康成人(26-62岁)使用对比增强液体丸进行透视吞咽研究。在整个口咽期对CoMs进行跟踪。分析每位参与者多次吞咽以评估个体内一致性。k均值聚类和轮廓分析应用于CoM轨迹数据,以评估模式的可重复性并探索潜在的年龄相关差异。结果:CoM轨迹在个体之间高度一致(剪影得分= 0.718)。聚类揭示了与年龄相关的模式:年长的参与者表现出更集中的运动轨迹,而年轻的参与者则表现出更多的横向运动。不同年龄组之间在丸降和咽协调方面存在其他差异。结论和意义:Bolus CoM轨迹分析是评估吞咽运动学的可行且可重复的方法。这些轨迹可能代表个性化的运动特征,有助于识别与年龄相关的细微变化。研究结果强调了个性化吞咽困难评估和康复策略的必要性。
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引用次数: 0
Tracheostomy outcomes and perioperative management in a Danish secondary care ENT department. 丹麦二级护理耳鼻喉科气管切开术结果和围手术期处理。
IF 1 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-01 Epub Date: 2025-09-23 DOI: 10.1080/00016489.2025.2561917
Martin Mølhave, Zaki Leo Olsen, Sara Svanesøe, Ali Abood

Background: Tracheostomy is widely used in critically ill patients, yet limited clinical data exist from Danish ENT departments.

Aims/objectives: To describe clinical outcomes and perioperative care in patients undergoing tracheostomy at a secondary ENT department in Denmark.

Material and methods: This retrospective cohort study included all adult patients who underwent tracheostomy at Gødstrup Hospital between 2019 and 2024. Data were extracted from electronic records. Postoperative pneumonia was the primary outcome; secondary outcomes included perioperative care assessment and in-hospital mortality.

Results: Seventy-seven patients were included, of whom 71 were evaluable for pneumonia outcome. Postoperative pneumonia occurred in 63% of patients. Neurological comorbidity was more frequent among patients with pneumonia (31% versus 8%, p = 0.037). Prophylactic antibiotics alone did not reduce pneumonia rates (61% versus 67%, p = 0.81). Postoperative dysphagia screening, pulmonary physiotherapy, and dietetic referral were more common in patients with pneumonia. In-hospital mortality was 14%, primarily in patients with prolonged intubation due to non-ENT causes. No deaths were directly related to the procedure.

Conclusions and significance: Postoperative pneumonia rates were high and associated with neurological comorbidity. Prophylactic antibiotics alone did not reduce pneumonia rates. These findings highlight the need for structured perioperative care in patients undergoing tracheostomy.

背景:气管切开术广泛应用于危重患者,但丹麦耳鼻喉科的临床资料有限。目的/目的:描述丹麦二级耳鼻喉科气管切开术患者的临床结果和围手术期护理。材料和方法:本回顾性队列研究纳入了2019年至2024年间在Gødstrup医院接受气管切开术的所有成年患者。数据是从电子记录中提取的。术后肺炎是主要结局;次要结局包括围手术期护理评估和住院死亡率。结果:纳入77例患者,其中71例可评估肺炎结局。63%的患者发生术后肺炎。神经系统共病在肺炎患者中更为常见(31%比8%,p = 0.037)。单独使用预防性抗生素并不能降低肺炎发病率(61%对67%,p = 0.81)。术后吞咽困难筛查、肺物理治疗和饮食转诊在肺炎患者中更为常见。住院死亡率为14%,主要是由于非耳鼻喉科原因导致插管时间延长的患者。没有与手术直接相关的死亡。结论和意义:术后肺炎发生率高,并伴有神经系统合并症。单独使用预防性抗生素并不能降低肺炎的发病率。这些发现强调了气管切开术患者需要有组织的围手术期护理。
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引用次数: 0
Correction. 修正。
IF 1 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-01 Epub Date: 2025-10-10 DOI: 10.1080/00016489.2025.2572263
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引用次数: 0
Cognitive function assessment in patients with uncompensated vestibular neuritis. 非代偿性前庭神经炎患者的认知功能评估。
IF 1 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-01 Epub Date: 2025-10-10 DOI: 10.1080/00016489.2025.2561914
Bahareh Khavarghazalani, Maryam Emadi, Behnoush Kamali, Morteza Hamidi Nahrani, Bita Ghorbani Aghdam

Background: The vestibular system is essential for spatial orientation and is increasingly implicated in higher-order cognitive processes.

Objective: To investigate specific cognitive domains affected by unilateral vestibular neuritis (VN).

Methods: In a cross-sectional comparative study, 30 patients with uncompensated unilateral VN and 30 age- and sex-matched healthy controls were assessed. Participants completed a cognitive test battery including reaction time tasks, visuospatial memory (Corsi Block-Tapping Test), processing speed and response inhibition (Visual Stroop Task), verbal fluency, working memory (Reverse Digit Span), and attention (Serial 7 Subtraction). Between-group comparisons were conducted using independent t-tests or Mann-Whitney U-tests, with effect sizes calculated using Cohen's d.

Results: No significant demographic differences were observed between groups. Patients with VN performed significantly worse on the Corsi Block-Tapping Test (p = 0.004, d = 1.02) and exhibited prolonged reaction times in the choice reaction task and incongruent Stroop condition (p = 0.01, d = 0.8). No significant differences were found in other cognitive domains.

Conclusion: Unilateral VN is associated with deficits in visuospatial memory and slowed processing speed. These findings emphasize the vestibular system's role in cognition and support the inclusion of cognitive assessment and rehabilitation in the management of vestibular disorders.

背景:前庭系统对空间定位至关重要,并且越来越多地涉及高阶认知过程。目的:探讨单侧前庭神经炎(VN)对特定认知域的影响。方法:在一项横断面比较研究中,对30例无代偿性单侧VN患者和30例年龄和性别匹配的健康对照进行了评估。参与者完成了一系列认知测试,包括反应时间任务、视觉空间记忆(科西积木敲击测试)、处理速度和反应抑制(视觉Stroop任务)、语言流畅性、工作记忆(反向数字广度)和注意力(数列7减法)。组间比较采用独立t检验或Mann-Whitney u检验,效应量采用Cohen’s d计算。结果:组间未观察到显著的人口统计学差异。VN患者在Corsi block - tap Test中的表现较差(p = 0.004, d = 1.02),在选择反应任务和不一致Stroop条件中的反应时间较长(p = 0.01, d = 0.8)。在其他认知领域没有发现显著差异。结论:单侧VN与视觉空间记忆缺陷和加工速度减慢有关。这些发现强调了前庭系统在认知中的作用,并支持将认知评估和康复纳入前庭疾病的治疗。
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引用次数: 0
Application of circulating tumor DNA analysis in detecting Minimal residual disease (MRD) after surgery for locally advanced head and neck squamous cell carcinoma: a preliminary study. 循环肿瘤DNA分析在局部晚期头颈部鳞状细胞癌术后微小残留病变(MRD)检测中的应用:初步研究
IF 1 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-01 Epub Date: 2025-09-26 DOI: 10.1080/00016489.2025.2561924
Xiaolian Fang, Zheng Yang, Jing Zhou, Xiaohong Chen, Pingdong Li

Background: Traditional imaging and pathological examinations lack sufficient sensitivity for detecting minimal residual disease (MRD), limiting early identification of subclinical recurrence in head and neck squamous cell carcinoma (HNSCC).

Aims/objectives: To explore the clinical utility of dynamic circulating tumor DNA (ctDNA) monitoring in detecting MRD after surgery for locally advanced HNSCC.

Material and methods: Sixteen patients with locally advanced HNSCC who underwent radical treatment were enrolled. Peripheral blood samples were collected preoperatively and one week to five years postoperatively for ctDNA analysis. Tumor tissue targeted sequencing and clinicopathological parameters were integrated to evaluate the sensitivity, specificity, and prognostic value of MRD detection.

Results: The preoperative ctDNA positivity rate was 81.3% (13/16), with a median content of 22.6 hGE/ml (range: 0.45-131.92). High-frequency genetic alterations included TP53 mutations (81.3%, 13/16), with hotspot mutations such as p.R273C, p.H193L, and p.R342. Copy number reduction in CDKN2A (43.8%, 7/16) and PIK3CA mutations (18.8%, 3/16) were the main driver alterations. One patient with hypopharyngeal carcinoma (T3N2bM0) tested ctDNA-positive 1.5 months postoperatively, which was 6.5 months earlier than radiological recurrence (tongue metastasis detected 8 months postoperatively).

Conclusions and significance: Dynamic ctDNA monitoring effectively identifies postoperative MRD in HNSCC.

背景:传统的影像学和病理学检查在检测微小残留病变(MRD)方面缺乏足够的敏感性,限制了头颈部鳞状细胞癌(HNSCC)亚临床复发的早期识别。目的:探讨动态循环肿瘤DNA (ctDNA)监测在局部晚期HNSCC术后MRD检测中的临床应用。材料和方法:16例局部晚期HNSCC患者接受根治性治疗。术前和术后1周至5年采集外周血样本进行ctDNA分析。结合肿瘤组织靶向测序和临床病理参数,评估MRD检测的敏感性、特异性和预后价值。结果:术前ctDNA阳性率为81.3%(13/16),中位含量为22.6 hGE/ml(范围:0.45 ~ 131.92)。高频基因改变包括TP53突变(81.3%,13/16),其中p.R273C、p.H193L、p.R342为热点突变。CDKN2A拷贝数减少(43.8%,7/16)和PIK3CA突变(18.8%,3/16)是主要的驱动因素。1例下咽癌(T3N2bM0)患者术后1.5个月检测ctdna阳性,比影像学复发早6.5个月(术后8个月检测到舌转移)。结论及意义:动态ctDNA监测可有效识别HNSCC术后MRD。
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引用次数: 0
Impact of the cytokine milieu on fibroblasts and their characterization in chronic rhinosinusitis with nasal polyps. 细胞因子环境对慢性鼻窦炎伴鼻息肉成纤维细胞的影响及其特征。
IF 1 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-01 Epub Date: 2025-10-08 DOI: 10.1080/00016489.2025.2567407
Toshiyuki Matsuyama, Reika Kawabata-Iwakawa, Hideyuki Takahashi, Yuichi Tomidokoro, Masaomi Motegi, Kazuaki Chikamatsu

Background: Nasal polyps (NP) contribute to treatment resistance in chronic rhinosinusitis with nasal polyps (CRSwNP); however, the cellular and molecular mechanisms underlying nasal polypogenesis are not completely understood.

Objectives: To investigate whether the characteristics of fibroblasts differ under the surrounding tissue environment.

Material and methods: Patients with CRSwNP were divided into two groups based on the eosinophil infiltration in the NP; the gene expression levels were evaluated. Fibroblasts established from NP were assessed for functional changes following cytokine stimulation, and RNA sequencing (RNA-seq) was performed.

Results: IL5 and IL13 expression was higher, and IFNG and TNF lower, in NP from eosinophilic CRS (ECRS) patients compared to non-ECRS. FOXP3 expression was significantly upregulated in ECRS patients. Cytokine-stimulated fibroblasts from both ECRS and non-ECRS showed similar expression of fibroblast-to-myofibroblast transition-related genes and significantly reduced migratory capacity following IL-13 and TNF-α treatment. RNA sequencing revealed six and thirty-five significant activated and inactivated signaling pathways, respectively, in the Diseases Bio Functions analysis.

Conclusions and significance: Fibroblasts contribute to nasal polypogenesis irrespective of inflammation type in CRSwNP. Although their behavior is regulated by the immune microenvironment, our findings also highlight fibroblasts as potential therapeutic targets, supporting both endotypic classification and novel treatment strategies.

背景:鼻息肉(NP)是慢性鼻窦炎伴鼻息肉(CRSwNP)治疗耐药的因素之一;然而,鼻腔息肉形成的细胞和分子机制尚不完全清楚。目的:探讨成纤维细胞在周围组织环境下的特性差异。材料与方法:根据NP中嗜酸性粒细胞的浸润情况将CRSwNP患者分为两组;评估基因表达水平。在细胞因子刺激后,评估从NP中建立的成纤维细胞的功能变化,并进行RNA测序(RNA-seq)。结果:与非ECRS相比,嗜酸性CRS (ECRS)患者NP中IL5和IL13的表达较高,IFNG和TNF的表达较低。在ECRS患者中FOXP3表达显著上调。细胞因子刺激的ECRS和非ECRS成纤维细胞在IL-13和TNF-α处理后显示成纤维细胞向肌成纤维细胞过渡相关基因的表达相似,迁移能力显著降低。RNA测序在疾病生物功能分析中分别揭示了6个和35个重要的激活和失活信号通路。结论和意义:在CRSwNP中,无论炎症类型如何,成纤维细胞都有助于鼻息肉形成。尽管它们的行为受到免疫微环境的调节,但我们的研究结果也强调了成纤维细胞作为潜在的治疗靶点,支持内源性分类和新的治疗策略。
{"title":"Impact of the cytokine milieu on fibroblasts and their characterization in chronic rhinosinusitis with nasal polyps.","authors":"Toshiyuki Matsuyama, Reika Kawabata-Iwakawa, Hideyuki Takahashi, Yuichi Tomidokoro, Masaomi Motegi, Kazuaki Chikamatsu","doi":"10.1080/00016489.2025.2567407","DOIUrl":"10.1080/00016489.2025.2567407","url":null,"abstract":"<p><strong>Background: </strong>Nasal polyps (NP) contribute to treatment resistance in chronic rhinosinusitis with nasal polyps (CRSwNP); however, the cellular and molecular mechanisms underlying nasal polypogenesis are not completely understood.</p><p><strong>Objectives: </strong>To investigate whether the characteristics of fibroblasts differ under the surrounding tissue environment.</p><p><strong>Material and methods: </strong>Patients with CRSwNP were divided into two groups based on the eosinophil infiltration in the NP; the gene expression levels were evaluated. Fibroblasts established from NP were assessed for functional changes following cytokine stimulation, and RNA sequencing (RNA-seq) was performed.</p><p><strong>Results: </strong><i>IL5</i> and <i>IL13</i> expression was higher, and <i>IFNG</i> and <i>TNF</i> lower, in NP from eosinophilic CRS (ECRS) patients compared to non-ECRS. <i>FOXP3</i> expression was significantly upregulated in ECRS patients. Cytokine-stimulated fibroblasts from both ECRS and non-ECRS showed similar expression of fibroblast-to-myofibroblast transition-related genes and significantly reduced migratory capacity following IL-13 and TNF-α treatment. RNA sequencing revealed six and thirty-five significant activated and inactivated signaling pathways, respectively, in the Diseases Bio Functions analysis.</p><p><strong>Conclusions and significance: </strong>Fibroblasts contribute to nasal polypogenesis irrespective of inflammation type in CRSwNP. Although their behavior is regulated by the immune microenvironment, our findings also highlight fibroblasts as potential therapeutic targets, supporting both endotypic classification and novel treatment strategies.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1064-1072"},"PeriodicalIF":1.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term follow-up of auditory neuropathy children after cochlear implants or the use of hearing aids. 耳蜗植入或使用助听器后听神经病变患儿的长期随访。
IF 1 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-10-31 DOI: 10.1080/00016489.2025.2573820
Kimitaka Kaga
{"title":"Long-term follow-up of auditory neuropathy children after cochlear implants or the use of hearing aids.","authors":"Kimitaka Kaga","doi":"10.1080/00016489.2025.2573820","DOIUrl":"https://doi.org/10.1080/00016489.2025.2573820","url":null,"abstract":"","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-8"},"PeriodicalIF":1.0,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145420961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An investigation of the effects of various proprioceptive inputs on vestibuloocular reflex and otolith organs. 不同本体感觉输入对前庭反射和耳石器官影响的研究。
IF 1 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-10-01 Epub Date: 2025-08-31 DOI: 10.1080/00016489.2025.2549087
Deniz Uğur Cengiz, Ercan Karababa, Sanem Can Sarıoğlu, Buşra Mazooğlu, Sümeyye Demirel Birişik, Almıla Avşar, Hatice Kübra Bozkurt, İsmail Demir

Background: The vestibular system is crucial for balance and gaze stability. Proprioceptive inputs from the musculoskeletal system significantly contribute to vestibular processing, especially under postural challenge.

Objectives: To examine how proprioceptive inputs in various body positions affect the vestibulo-ocular reflex (VOR) and otolith organ function.

Materials and methods: Thirty healthy adults (18-40 years, no vertiginous symptoms) underwent cervical and ocular vestibular evoked myogenic potentials (c-VEMP, o-VEMP) and video head impulse testing (v-HIT) in four positions: sitting, standing, one-leg standing, and on a balance disk. Primary outcomes included latency, amplitude, and asymmetry for VEMPs; gain and asymmetry for semicircular canals (SCCs) via v-HIT.

Results: c-VEMP latencies and amplitudes did not differ significantly across positions; however, amplitude asymmetry was significantly different between sitting and other conditions (p = .041). o-VEMP results remained consistent (p > .05). v-HIT revealed progressively reduced SCC gain from sitting to disk stance, with significant decreases in lateral SCCs (p < .05) and vertical SCCs (p < .001); asymmetry remained stable.

Conclusions and significance: Increased proprioceptive demand reduced VOR gain and modified c-VEMP asymmetry, reflecting enhanced vestibulospinal engagement. These outcomes likely arise from multisensory interactions rather than proprioceptive input alone, underscoring integrated sensory contributions to postural control.

背景:前庭系统对平衡和凝视稳定性至关重要。来自肌肉骨骼系统的本体感觉输入显著促进前庭处理,特别是在姿势挑战下。目的:探讨不同体位本体感觉输入对前庭眼反射(VOR)和耳石器官功能的影响。材料和方法:30名健康成人(18-40岁,无眩晕症状)在坐、站、单腿站立和平衡盘上四种体位进行颈椎和眼前庭诱发肌原电位(c-VEMP, o-VEMP)和视频头脉冲测试(v-HIT)。主要结局包括vemp的潜伏期、幅度和不对称性;v-HIT对半规管(SCCs)的增益和不对称性。结果:不同体位的c-VEMP潜伏期和振幅无显著差异;然而,振幅不对称性在坐姿和其他状态下有显著差异(p = 0.041)。o-VEMP结果保持一致(p < 0.05)。v-HIT显示,从坐位到盘位,SCC增益逐渐降低,侧位SCC显著降低(p)。结论和意义:本体感觉需求的增加降低了VOR增益,改变了c-VEMP不对称性,反映了前庭脊髓融合增强。这些结果可能是由多感觉相互作用而不是本体感觉输入引起的,强调了姿势控制的综合感觉贡献。
{"title":"An investigation of the effects of various proprioceptive inputs on vestibuloocular reflex and otolith organs.","authors":"Deniz Uğur Cengiz, Ercan Karababa, Sanem Can Sarıoğlu, Buşra Mazooğlu, Sümeyye Demirel Birişik, Almıla Avşar, Hatice Kübra Bozkurt, İsmail Demir","doi":"10.1080/00016489.2025.2549087","DOIUrl":"10.1080/00016489.2025.2549087","url":null,"abstract":"<p><strong>Background: </strong>The vestibular system is crucial for balance and gaze stability. Proprioceptive inputs from the musculoskeletal system significantly contribute to vestibular processing, especially under postural challenge.</p><p><strong>Objectives: </strong>To examine how proprioceptive inputs in various body positions affect the vestibulo-ocular reflex (VOR) and otolith organ function.</p><p><strong>Materials and methods: </strong>Thirty healthy adults (18-40 years, no vertiginous symptoms) underwent cervical and ocular vestibular evoked myogenic potentials (c-VEMP, o-VEMP) and video head impulse testing (v-HIT) in four positions: sitting, standing, one-leg standing, and on a balance disk. Primary outcomes included latency, amplitude, and asymmetry for VEMPs; gain and asymmetry for semicircular canals (SCCs) via v-HIT.</p><p><strong>Results: </strong>c-VEMP latencies and amplitudes did not differ significantly across positions; however, amplitude asymmetry was significantly different between sitting and other conditions (<i>p</i> = .041). o-VEMP results remained consistent (<i>p</i> > .05). v-HIT revealed progressively reduced SCC gain from sitting to disk stance, with significant decreases in lateral SCCs (<i>p</i> < .05) and vertical SCCs (<i>p</i> < .001); asymmetry remained stable.</p><p><strong>Conclusions and significance: </strong>Increased proprioceptive demand reduced VOR gain and modified c-VEMP asymmetry, reflecting enhanced vestibulospinal engagement. These outcomes likely arise from multisensory interactions rather than proprioceptive input alone, underscoring integrated sensory contributions to postural control.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"911-920"},"PeriodicalIF":1.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validity and reliability of the Turkish version of the "cochlear implant use questionnaire". 土耳其版“人工耳蜗使用问卷”的效度和信度。
IF 1 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-10-01 Epub Date: 2025-09-23 DOI: 10.1080/00016489.2025.2563043
Aysenur Aykul Yagcioglu, Betul Cicek Cinar

Background: Daily and regular use of cochlear implant (CI) processors is crucial for adapting to them and achieving optimal benefits. However, some obstacles to using CI processors exist, and it is important to identify these barriers and find solutions.

Purpose: This research evaluated the validity and reliability of the Turkish version of the Cochlear Implant Use Questionnaire (CIUQ) related to the barriers to cochlear implant use.

Methods: This is a cross-cultural adaptation of the CIUQ questionnaire. One hundred thirty-four adult CI users aged 18-60 participated in the study. This study evaluated the construct validity of the CIUQ using confirmatory factor analysis and the internal consistency reliability using Cronbach's alpha coefficient.

Results: In the current study, the Kaiser-Meyer-Olkin coefficient was 0.75. The fit values obtained from the CFA applied to the CIUQ were satisfactory and within acceptable limits. Cronbach's α internal consistency coefficient for subscales ranged from 0.70 to 0.78, and the value was 0.8 for the overall scale.

Conclusion: The Turkish adaptation of the CIUQ, which was developed to measure CI usage habits and barriers to daily CI usage, was determined to be a reliable and valid measurement tool for adults using CI.

背景:日常和定期使用人工耳蜗(CI)处理器对于适应它们并获得最佳效益至关重要。然而,使用CI处理器存在一些障碍,识别这些障碍并找到解决方案非常重要。目的:本研究评估土耳其版人工耳蜗使用问卷(CIUQ)与人工耳蜗使用障碍相关的效度和信度。方法:对CIUQ问卷进行跨文化改编。134名年龄在18-60岁的成年CI使用者参与了这项研究。本研究采用验证性因子分析评估CIUQ的结构效度,采用Cronbach’s alpha系数评估内部一致性信度。结果:本研究中,Kaiser-Meyer-Olkin系数为0.75。应用于CIUQ的CFA拟合值是令人满意的,在可接受的范围内。子量表的Cronbach's α内部一致性系数为0.70 ~ 0.78,整体量表的Cronbach's α内部一致性系数为0.8。结论:土耳其的CIUQ是用来测量CI使用习惯和日常CI使用障碍的,被认为是成年人使用CI的可靠和有效的测量工具。
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引用次数: 0
Diagnostic utility of videofluoroscopic swallowing study in patients presenting with the sensation of food sticking in the throat: a retrospective analysis. 影像透视吞咽研究对有食物卡在喉咙的病人的诊断价值:回顾性分析。
IF 1 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-10-01 Epub Date: 2025-09-26 DOI: 10.1080/00016489.2025.2561920
Mustafa Said Tekin, Fatma Nerse

Background: The sensation of food 'sticking' in the throat is a frequent but diagnostically challenging symptom that often persists despite normal ENT findings. Videofluoroscopic swallowing study (VFSS) enables dynamic evaluation of swallowing physiology and may reveal hidden abnormalities.

Aims/objectives: To assess the diagnostic yield of VFSS in patients with throat-related dysphagia, focusing on abnormality type, localisation, and bolus consistency.

Materials and methods: This retrospective study included 42 patients with persistent symptoms but normal endoscopic examinations between January 2020 and January 2025. Reflux-related findings were excluded. VFSS was performed with nectar-thick liquids, pudding, and solids. Abnormalities were classified by site and etiology. Concordance between symptom site and VFSS findings was analysed.

Results: VFSS detected abnormalities in 74% of patients, predominantly physiological (65%) and within the oesophageal body (55%). Symptom-pathology concordance was low (26%). Solids provided the highest diagnostic yield (50%).

Conclusions and significance: VFSS is valuable in unexplained dysphagia with normal ENT findings, particularly when symptoms occur with solids. Including oesophageal evaluation and varied consistencies improves diagnostic precision and guides management.

背景:食物“卡”在喉咙的感觉是一种常见的但诊断上具有挑战性的症状,尽管正常的耳鼻喉科检查结果仍然存在。视频透视吞咽研究(VFSS)可以动态评估吞咽生理学,并可能揭示隐藏的异常。目的:评估VFSS对咽喉相关吞咽困难患者的诊断率,重点关注异常类型、定位和剂量一致性。材料和方法:本回顾性研究包括42例持续症状但内镜检查正常的患者,时间为2020年1月至2025年1月。排除了反流相关的发现。VFSS用花蜜厚的液体、布丁和固体进行。根据部位和病因对异常进行分类。分析症状部位与VFSS表现的一致性。结果:VFSS在74%的患者中检测到异常,主要是生理性的(65%)和食道内的(55%)。症状-病理一致性较低(26%)。固体的诊断率最高(50%)。结论和意义:VFSS在耳鼻喉科检查正常但原因不明的吞咽困难中很有价值,特别是当症状出现在固体时。包括食道评估和不同的一致性提高了诊断的准确性和指导管理。
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引用次数: 0
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Acta Oto-Laryngologica
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