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50 Years of terrorism in Belgium: a review of 121 incidents in the global terrorism database. 比利时恐怖主义 50 年:对全球恐怖主义数据库中 121 起事件的审查。
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2024-10-01 Epub Date: 2024-02-01 DOI: 10.1080/00015458.2024.2308400
Harald De Cauwer, Luc J Mortelmans, Francis Somville, Patrick Cras

Objectives: Belgium is not only prone to inland terrorism but also attracts terrorist factions aiming at various political, diplomatic, military, and/or religious targets. This study aimed to identify and characterize all documented terrorist attacks in Belgium reported to the Global Terrorism Database (GTD) over a period of 50 years.

Methods: The GTD was searched for all terrorist attacks in Belgium between 1970 and 2019. Analyses were performed on temporal factors, location, target type, attack and weapon type, attacker type, and number of casualties or hostages.

Results: In 50 years, 121 incidents accounted for 80 confirmed fatalities and 498 injured people. Bombings and explosions were the most frequently identified attack type (46.3%), followed by assassination (16.5%), infrastructure damage (15.7%) and armed or unarmed assaults (14.0%). Governmental and diplomatic institutions were the most frequent target (24.0%). For those perpetrators the GTD did have enough information we saw a timely change from far left and separatist dominating the early decades to Jihadi groups in the last decade, while anti-semitic factions were active in every decade.

Conclusion: In contrast to other studies, this study did not show an increase over time. Left-wing perpetrators dominated the eighties. In 50 years of terrorist activity in Belgium, the health care system was spared. Devastating mass casualty attacks challenging the health care system are rare in Belgium.

目标:比利时不仅容易发生内陆恐怖主义,而且还吸引了以各种政治、外交、军事和/或宗教目标为目标的恐怖主义派别。本研究旨在确定全球恐怖主义数据库(Global Terrorism Database,GTD)所收录的 50 年来比利时发生的所有恐怖袭击事件,并分析其特点:方法:在全球恐怖主义数据库(GTD)中搜索了 1970 年至 2019 年期间比利时发生的所有恐怖袭击事件。对时间因素、地点、目标类型、袭击和武器类型、袭击者类型以及伤亡或人质数量进行了分析:50 年间,121 起事件造成 80 人确认死亡,498 人受伤。炸弹和爆炸是最常见的袭击类型(46.3%),其次是暗杀(16.5%)、基础设施破坏(15.7%)和武装或非武装袭击(14.0%)。政府和外交机构是最常见的袭击目标(24.0%)。对于那些GTD掌握足够信息的犯罪者,我们看到了一个及时的变化,从最初几十年以极左和分裂主义为主,到最近十年以圣战组织为主,而反犹主义派别在每个十年都很活跃:与其他研究相比,本研究并未显示出随时间推移而增加的趋势。左翼犯罪分子在八十年代占主导地位。在比利时 50 年的恐怖活动中,医疗保健系统幸免于难。在比利时,针对医疗保健系统的大规模杀伤性袭击十分罕见。
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引用次数: 0
Pancreatic tuberculosis in an 18-year-old patient. 一名 18 岁患者的胰腺结核病。
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2024-10-01 Epub Date: 2024-08-02 DOI: 10.1080/00015458.2021.1928877
Laura Boutin, Mihane Nayeri, Julien Frandon, Frédéric Borie

An 18-year-old male patient presented with abdominal pain, nausea, and diarrhea. Subsequent laboratory investigations involving the patient's blood samples revealed an inflammatory syndrome. Subsequent radiographic investigations (CT scan, MRI, and endoscopic ultrasound with biopsies) led to the discovery of a heterogenic cystic lesion in the tail of the pancreas. Although the investigations orientated the diagnosis towards a pseudopapillary tumor, no certain pathological diagnosis could be obtained. After a multidisciplinary meeting, surgery was chosen as the designated therapeutic option. The patient underwent left pancreatectomy and no complications were encountered. The pathological examination revealed isolated pancreatic tuberculosis. Currently, the patient is under treatment and no longer presents any digestive symptoms.

摘要 一名 18 岁的男性患者因腹痛、恶心和腹泻就诊。随后对患者的血液样本进行的实验室检查发现了炎症综合征。随后的放射学检查(CT 扫描、核磁共振成像、内窥镜超声波和活组织检查)发现胰腺尾部有异源性囊性病变。虽然检查结果将其诊断为假乳头状瘤,但病理诊断并不明确。经过多学科会诊,最终选择了手术治疗。患者接受了左侧胰腺切除术,没有出现并发症。病理检查显示为孤立性胰腺结核。目前,患者正在接受治疗,不再出现任何消化道症状。
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引用次数: 0
Completely portal robotic lobectomy in lung cancer: is subcostal specimen removal necessary? 肺癌完全门机器人肺叶切除术:是否有必要切除肋下标本?
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2024-10-01 Epub Date: 2024-02-27 DOI: 10.1080/00015458.2024.2320510
Murat Akkuş, Yunus Seyrek

Background: The best place for specimen extraction is a relevant question since either after robotic or video-thoracoscopic lobectomy, both intercostal and subcostal routes can be potential extraction routes. In this study, we studied completely portal robotic lobectomies (CPRL-4) for pulmonary neoplasms to investigate the efficacy and feasibility of subcostal specimen removal by comparing the two techniques.

Material and methods: Between January 2014 and July 2021, data from 90 patients who underwent robotic thoracic surgery with a Da Vinci Surgical System SI (Intuitive Surgical Inc., Mountain View, California, USA) were collected and retrospectively analyzed. Out of 90 patients, we analyzed 36 CPRL-4 cases. We removed specimens traditionally via intercostal utility thoracotomy in the first 22 patients (group A) and via subcostal incision in the next consecutive 14 patients (group B). Operative parameters, postoperative parameters, the visual analog scale (VAS) and SF36 life quality scoring were comparatively analyzed.

Results: The mean docking time was significantly higher in group B than in group A (26.2 ± 5.3 vs 17.8 ± 4.1) (p = .001). In terms of early-stage postoperative pain, group B had significantly lower pain scores compared to group A (p < .05). There was no significant difference between the groups in terms of SF36 life quality scoring.

Conclusion: We can conclude that performing a subcostal incision is not a sophisticated process, though it significantly prolongs the docking time. Although our study is based on a small group, we noticed that removing the specimen through the subcostal incision after CPRL-4 is potentially useful, has several advantages and it is a practical, feasible, and safe method.

Clinical registration number: 2018/57.

背景:无论是机器人肺叶切除术还是视频胸腔镜肺叶切除术,肋间和肋下都是可能的标本取出路径,因此标本取出的最佳位置是一个相关问题。在这项研究中,我们对完全肺门机器人肺叶切除术(CPRL-4)进行了研究,通过比较两种技术来探讨肋下标本取出的有效性和可行性:2014年1月至2021年7月期间,我们收集并回顾性分析了90例使用达芬奇手术系统SI(直觉外科公司,美国加利福尼亚州山景城)进行机器人胸腔手术的患者数据。在 90 例患者中,我们分析了 36 例 CPRL-4 病例。在前22例患者(A组)中,我们通过肋间实用胸廓切开术传统地取出了标本,在接下来的14例患者(B组)中,我们通过肋下切口取出了标本。对手术参数、术后参数、视觉模拟量表(VAS)和 SF36 生活质量评分进行了比较分析:结果:B组的平均对接时间明显高于A组(26.2 ± 5.3 vs 17.8 ± 4.1)(P = 0.001)。在术后早期疼痛方面,B 组的疼痛评分明显低于 A 组(P 结论:B 组的疼痛评分明显低于 A 组(P = 0.001):我们可以得出结论,虽然肋下切口会大大延长对接时间,但它并不是一个复杂的过程。虽然我们的研究是基于一个小群体,但我们注意到,在 CPRL-4 术后通过肋下切口取出标本是有潜在作用的,它有几个优点,而且是一种实用、可行和安全的方法。
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引用次数: 0
Pericardial fenestration and thoracic duct ligation for treatment of chylopericardium as first symptom of underlying generalized lymphatic anomaly: a case report 用心包切开术和胸导管结扎术治疗作为潜在全身淋巴异常首发症状的乳糜心包炎:病例报告
IF 0.8 4区 医学 Q4 SURGERY Pub Date : 2024-09-18 DOI: 10.1080/00015458.2024.2406606
Roza S. Makarian, Oana Mirea, Peter Verhamme, Karel M. Smeyers, Evelien Berkmans, Victor Raicea, Mihaela Berceanu, Dirk Van Raemdonck, Laurens J. Ceulemans
Chylopericardium represents a rare condition of chyle accumulation within the pericardial sac, caused by abnormal thoracic duct anatomy or prolonged increased pressure. Nothing by mouth (NPO) polic...
胆汁性心包炎是一种罕见的心包囊内淤积胆汁的病症,由胸导管解剖异常或长期压力增高引起。口服无盐疗法(NPO)...
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引用次数: 0
Literature review on management of prosthetic graft infections after supra-aortic bypass surgery, based on a case report 基于病例报告的主动脉上搭桥手术后人工移植物感染管理文献综述
IF 0.8 4区 医学 Q4 SURGERY Pub Date : 2024-09-11 DOI: 10.1080/00015458.2024.2398849
Zohal Fazli, Alexander Croo, Karen Van Langenhove, Gilles Uijtterhaegen, Nathalie Moreels, Frank Vermassen, Isabelle Van Herzeele, Caren Randon
Graft infections of supra-aortic bypasses are rare, but often life-threatening. Guidelines for treatment of graft infections recommend systemic antibiotics and complete graft removal, followed by i...
主动脉上分流术的移植物感染非常罕见,但通常会危及生命。治疗移植物感染的指南建议使用全身抗生素并完全移除移植物,然后再进行人工呼吸。
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引用次数: 0
Surgical training; destination unknown? 外科培训;去向不明?
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2024-08-08 DOI: 10.1080/00015458.2024.2391176
Niels Komen, Marian Vanhoeij, Paul De Leyn, Frederik Berrevoet, Piet Pattyn, Guy Hubens

Background A surgical fellowship allows both additional training as well as maintenance of surgical skills while searching for a steady job. As the presence of fellows usually does not results in a measurably higher productivity, fellowshipsmay be considered a form of disguised unemployment. The aim of this study is to evaluate the career flow of a surgical trainee to a staff position and to determine the number of surgeons working on temporary basis within the general surgery workforce in Flanders.Methods All surgeons graduated in Flanders between 2000 and 2022 were invited to fill out a web-based survey concerning their current and past employment. Reminders were sent out after 2 and 4 weeks. Statistical analysis was performed with SPSS version 27.0 (IBM Inc., Chicago, IL, USA.)Results Response rate was 64% (292/457) with 76% of respondents currently working as surgeons, 14% (38) as fellows and 10% working outside the surgical domain. Eighty-two percent of current fellows graduated in 2019 or later. Thirty-one percent of surgeons graduated in 2019 are still working as fellows. For surgeons graduated in 2020, 2021 and 2022 this is 45%, 80% and 90% respectively. Compared to staff surgeons the number of additional training years (2,8 ± 1,0 vs 2,2 ± 1,3; p = 0,009). and the number of applications (6,6 ± 5 vs 3,3 ± 3; p < 0,001) is significantly higher for current fellowsConclusion This study shows that disguised unemployment is present in the general surgical community in Flanders. The status of "fellow" should be incorporated in calculations concerning future needs of the surgical workforce in order to prevent open unemployment.

背景 外科研究员可以在寻找稳定工作的同时接受额外的培训并保持外科技能。由于研究员的存在通常不会显著提高工作效率,因此研究员可能被认为是一种变相的失业。本研究的目的是评估从外科实习生到职员的职业流向,并确定佛兰德普外科队伍中从事临时工作的外科医生人数。2 周和 4 周后分别发出提醒函。结果 答复率为 64%(292/457),其中 76% 的受访者目前担任外科医生,14%(38 人)担任研究员,10% 在外科领域以外工作。82%的研究员毕业于 2019 年或之后。在 2019 年毕业的外科医生中,有 31% 仍在担任研究员。2020、2021 和 2022 年毕业的外科医生中,这一比例分别为 45%、80% 和 90%。与外科医生相比,在职研究员的额外培训年数(2,8 ± 1,0 vs 2,2 ± 1,3;p = 0,009)和申请数量(6,6 ± 5 vs 3,3 ± 3;p < 0,001)明显高于外科医生。在计算未来外科劳动力需求时,应将 "研究员 "身份纳入其中,以防止公开失业。
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引用次数: 0
The impact of intraoperative neural monitoring during papillary thyroid cancer surgery on completeness of thyroidectomy and thyroglobulin response: a propensity-score matched study. 甲状腺乳头状癌手术期间术中神经监测对甲状腺切除术完整性和甲状腺球蛋白反应的影响:倾向分数匹配研究
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2024-08-01 Epub Date: 2024-01-17 DOI: 10.1080/00015458.2024.2305501
Yalin Iscan, Berke Sengun, Irem Karatas, Hasan Berke Atalay, Ismail Cem Sormaz, Semen Onder, Gulcin Yegen, Hulya Hacisahinogullari, Fatih Tunca, Yasemin Giles Senyurek

Background: Intraoperative neural monitoring (IONM) has been utilized for a variety of thyroid pathologies, including papillary thyroid carcinoma (PTC). Remnant thyroid tissue following total thyroidectomy (TT) in patients with PTC is associated with increased recurrence. The aim of this study is to investigate whether the use of IONM in PTC surgery has an impact on the completeness of thyroidectomy.

Methods: Retrospectively, patients with preoperative diagnosis of PTC, who underwent TT in a tertiary center were reviewed. They were grouped based on the IONM usage, and 1:1 propensity-score match was performed. Primary outcome was the completeness of thyroidectomy, determined by measuring postoperative stimulated thyroglobulin levels (sTg).

Results: Among 274 clinically node-negative PTC patients who underwent TT and ipsilateral prophylactic central lymph-node dissection, a total of 170 patients (85:85) were matched. Postoperative sTg levels were significantly lower in the IONM group (1 ng/dL vs. 0.4 ng/dL; p < 0.01) with higher percentage of the patients with sTg levels <1 ng/ml (50.6% vs. 69.4%; p = 0.01). More patients in the no-IONM group received RAI ablation with significantly higher doses (mean mci: 120 vs. 102; p = 0.02).

Conclusion: The use of IONM during thyroidectomy provides improvement in the completeness of thyroidectomy and reduction in postoperative sTg levels which can be used as a guide by clinicians to avoid RAI ablation in selected PTC patients and to adjust low ablative doses in patients who are scheduled for remnant ablation.

背景术中神经监测(IONM)已被用于包括甲状腺乳头状癌(PTC)在内的多种甲状腺病变。PTC患者甲状腺全切除术(TT)后残留的甲状腺组织与复发率增加有关。本研究旨在探讨在PTC手术中使用IONM是否会影响甲状腺切除术的完整性。方法回顾性研究了在一家三级中心接受TT手术的术前诊断为PTC的患者。根据IONM的使用情况对患者进行分组,并进行1:1倾向分数匹配。结果在274例临床结节阴性、接受TT和同侧预防性中央淋巴结清扫术的PTC患者中,共有170例患者(85:85)进行了匹配。IONM 组的术后 sTg 水平明显较低(1ng/dL vs. 0.4ng/dL;p
{"title":"The impact of intraoperative neural monitoring during papillary thyroid cancer surgery on completeness of thyroidectomy and thyroglobulin response: a propensity-score matched study.","authors":"Yalin Iscan, Berke Sengun, Irem Karatas, Hasan Berke Atalay, Ismail Cem Sormaz, Semen Onder, Gulcin Yegen, Hulya Hacisahinogullari, Fatih Tunca, Yasemin Giles Senyurek","doi":"10.1080/00015458.2024.2305501","DOIUrl":"10.1080/00015458.2024.2305501","url":null,"abstract":"<p><strong>Background: </strong>Intraoperative neural monitoring (IONM) has been utilized for a variety of thyroid pathologies, including papillary thyroid carcinoma (PTC). Remnant thyroid tissue following total thyroidectomy (TT) in patients with PTC is associated with increased recurrence. The aim of this study is to investigate whether the use of IONM in PTC surgery has an impact on the completeness of thyroidectomy.</p><p><strong>Methods: </strong>Retrospectively, patients with preoperative diagnosis of PTC, who underwent TT in a tertiary center were reviewed. They were grouped based on the IONM usage, and 1:1 propensity-score match was performed. Primary outcome was the completeness of thyroidectomy, determined by measuring postoperative stimulated thyroglobulin levels (sTg).</p><p><strong>Results: </strong>Among 274 clinically node-negative PTC patients who underwent TT and ipsilateral prophylactic central lymph-node dissection, a total of 170 patients (85:85) were matched. Postoperative sTg levels were significantly lower in the IONM group (1 ng/dL vs. 0.4 ng/dL; <i>p</i> < 0.01) with higher percentage of the patients with sTg levels <1 ng/ml (50.6% vs. 69.4%; <i>p</i> = 0.01). More patients in the no-IONM group received RAI ablation with significantly higher doses (mean mci: 120 vs. 102; <i>p</i> = 0.02).</p><p><strong>Conclusion: </strong>The use of IONM during thyroidectomy provides improvement in the completeness of thyroidectomy and reduction in postoperative sTg levels which can be used as a guide by clinicians to avoid RAI ablation in selected PTC patients and to adjust low ablative doses in patients who are scheduled for remnant ablation.</p>","PeriodicalId":6935,"journal":{"name":"Acta Chirurgica Belgica","volume":" ","pages":"298-306"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139416066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Five years of robot-assisted ventral hernia repair: initial experience and surgical outcome. 机器人辅助腹股沟疝修补术五年:初步经验与手术效果。
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2024-08-01 Epub Date: 2024-01-17 DOI: 10.1080/00015458.2024.2304386
Van Zande Jaro, Krick Marc, Willaert Bart, Van Den Heede Klaas

Objective: Robot-assisted ventral hernia repair (RVHR) has become a feasible alternative for open ventral hernia repair showing fewer postoperative complications and satisfying short-term results. However, long-term results are scarce in current literature.

Methods: All consecutive patients who underwent robot-assisted surgery for ventral hernias from June 2018 until February 2023 were included. Patient records were retrospectively reviewed for indication, need for conversion, length of stay (LOS), postoperative complications, and postoperative pain.In addition, long-term (>24 months) results (recurrence, chronic pain, and esthetic satisfaction) were assessed by phone questionnaire.

Results: In total, 177 patients underwent a robot-assisted ventral hernia repair. Indication for surgery was incisional hernia (N = 109) and primary hernia (N = 68), including 124 cases with abdominal rectus diastasis. A TransAbdominal Retromuscular Umbilical Prosthesis (TARUP) was performed in 138 patients. Robotic Transversus Abdominis Release (TAR) and Extended Totally Extraperitoneal Repair (eTEP) were performed in 20 (11%) and 9 (5%) cases, respectively.Median LOS was 2 days for TARUP and 3.5 days for TAR. Minor complications occurred in 22 patients (16 TARUP, 5 TAR, 1 eTEP). The average pain score on the first postoperative day was 1.8/10. No risk factors for morbidity could be identified by uni- and multivariable analysis.Hernia recurrence developed in four (2%) patients. Chronic pain was reported in two (1%) cases. Seven (4%) patients had esthetic complaints.

Conclusion: Robot-assisted ventral hernia repair is a safe procedure with low postoperative pain and short LOS. Long-term results including recurrence and chronic pain are satisfying.

目的:机器人辅助腹股沟疝修补术(RVHR机器人辅助腹股沟疝修补术(RVHR)已成为开放性腹股沟疝修补术的可行替代方案,术后并发症少,短期效果令人满意。然而,目前的文献中缺乏长期结果:纳入2018年6月至2023年2月期间所有接受机器人辅助手术治疗腹股沟疝的连续患者。此外,还通过电话问卷评估了长期(>24 个月)结果(复发、慢性疼痛和美学满意度):共有177名患者接受了机器人辅助腹股沟疝修补术。手术指征为切口疝(109例)和原发性疝(68例),其中124例伴有腹直肌腹膜膨出。138名患者接受了经腹再肌性脐假体(TARUP)手术。TARUP的中位住院日为2天,TAR的中位住院日为3.5天。22例患者(16例TARUP、5例TAR、1例eTEP)出现轻微并发症。术后第一天的平均疼痛评分为 1.8/10。通过单变量和多变量分析,未发现发病风险因素。有两例(1%)患者出现慢性疼痛。结论:机器人辅助腹股沟疝气切除术是一种新的手术方式:机器人辅助腹股沟疝修补术是一种安全的手术,术后疼痛轻,住院时间短。结论:机器人辅助腹股沟疝修补术是一种安全的手术,术后疼痛轻,住院时间短,包括复发和慢性疼痛在内的长期效果令人满意。
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引用次数: 0
A pulmonary mass extending into the left atrium through the pulmonary vein: a rare diagnosis with an unusual origin. 通过肺静脉延伸至左心房的肺部肿块:一种起源不寻常的罕见诊断。
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2024-08-01 Epub Date: 2023-07-26 DOI: 10.1080/00015458.2023.2239550
Muhammet Ali Beyoglu, Mehmet Furkan Sahin, Muhammet Fethi Saglam, Huseyin Unsal Ercelik, Servet Guresci, Erdal Yekeler

Introduction: Myxofibrosarcoma usually occurs in the extremities of middle-aged to older adults. Metastatic myxofibrosarcomas generally emerge in the lung. In this case report, we aim to present a case of primary pulmonary myxofibrosarcoma with tumor thrombus extending into the left atrium without pulmonary vein or atrial invasion.

Case presentation: A 55-year-old male who was being followed up due to a pulmonary nodule presented with a mass extending from the left lower lobe to the left atrium. No extrathoracic malignancy was detected in the pre-operative examination. The mass extending into the left atrium without invasion was excised with the lower lobe of the left lung. A post-operative histopathological examination revealed myxofibrosarcoma.

Conclusion: Very few cases of cervical, thoracic wall, mediastinum and cardiac primary myxofibrosarcoma have been documented, and to the best of our knowledge, only one primary pulmonary myxofibrosarcoma case has previously been reported in the English literature. Here, we present a case of primary pulmonary myxofibrosarcoma that extended to the left atrium through the pulmonary vein. In such rare clinical presentations, intracardiac tumor resection should precede pulmonary resection due to the possibility of catastrophic tumor embolisms.

导言:肌纤维肉瘤通常发生在中老年人的四肢。转移性肌纤维肉瘤通常出现在肺部。在本病例报告中,我们旨在介绍一例原发性肺部肌纤维肉瘤,肿瘤血栓延伸至左心房,但未侵犯肺静脉或心房:一名 55 岁男性因肺部结节接受随访,发现肿块从左下叶延伸至左心房。术前检查未发现胸腔外恶性肿瘤。肿块延伸至左心房,但没有侵犯左肺,与左肺下叶一起切除。术后组织病理学检查显示为肌纤维肉瘤:据我们所知,此前只有一例原发性肺部肌纤维肉瘤在英文文献中有过报道。在此,我们介绍了一例通过肺静脉延伸至左心房的原发性肺肉纤维肉瘤。在这种罕见的临床表现中,心内肿瘤切除术应先于肺切除术,因为有可能发生灾难性的肿瘤栓塞。
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引用次数: 0
Aluminum potassium sulfate and tannic acid (ALTA) sclerotherapy for hemorrhoidal disease: a systematic review and meta-analysis. 治疗痔疮的硫酸铝钾和鞣酸(ALTA)硬化剂疗法:系统回顾和荟萃分析。
IF 0.6 4区 医学 Q4 SURGERY Pub Date : 2024-08-01 Epub Date: 2024-03-08 DOI: 10.1080/00015458.2024.2326273
Vasiliki Manaki, Vangelis Bontinis, Alkis Bontinis, Argirios Giannopoulos, Ioannis Kontes, Angeliki Chorti, Kiriakos Ktenidis

Background: We conducted a systematic review to assess the safety and efficacy of Aluminum potassium sulfate and tannic acid (ALTA) sclerotherapy for the treatment of hemorrhoidal disease.

Methods: Our study was conducted in accordance with the PRISMA statement (Preferred Reporting Items for Systematic Reviews and Meta-analyses) 2020. Primary endpoints included overall recurrence and type of recurrence while secondary endpoints included postoperative complications, reintervention, presence of rectal ulcer, rectal stricture, defecation abnormalities and perianal abscess. Α regression analysis, where the percentage of patients with grade II, III and IV hemorrhoidal disease was used as a covariate, was also performed.

Results: Twelve studies with 4249 patients met all the inclusion criteria and were eventually included. The crude and pooled estimates of the overall recurrence and complications by the end of follow-up were 10% (95% CI, 6.52%-14.08%) and 5.20% (95% CI, 2.59%-8.52%), respectively. Regression analysis displayed no correlation between recurrence and the grade of hemorrhoid disease II, β= -0.0012 (95% CI, -0.0074 to 0.0049) (p = .64), grade III β= -0.0006 (95% CI, -0.0056 to 0.0045) (p = .79) and grade IV β = 0.0025 (95% CI, -0.0075 to 0.0124). However, a trend suggestive of increased recurrence was observed in patient populations with a higher proportion of grade IV disease.

Conclusion: ALTA sclerotherapy may be a safe and viable alternative for patients with hemorrhoidal disease. Long-term follow-up and high-quality randomized controlled trials will help define the place of ALTA sclerotherapy in the armamentarium of treatment of hemorrhoids.

背景:我们对硫酸铝钾和鞣酸(ALTA)硬化剂疗法治疗痔疮的安全性和有效性进行了系统回顾:我们进行了一项系统综述,以评估硫酸铝钾和鞣酸(ALTA)硬化疗法治疗痔疮疾病的安全性和有效性:我们的研究是根据2020年PRISMA声明(系统综述和元分析首选报告项目)进行的。主要终点包括总复发率和复发类型,次要终点包括术后并发症、再次干预、直肠溃疡、直肠狭窄、排便异常和肛周脓肿。此外,还进行了Α回归分析,将II级、III级和IV级痔疮患者的百分比作为协变量:共有 12 项研究、4249 名患者符合所有纳入标准,最终被纳入研究。随访结束时的总复发率和并发症的粗略估计值和汇总估计值分别为 10%(95% CI,6.52% - 14.08%)和 5.20%(95% CI,2.59% - 8.52%)。回归分析表明,复发与痔疮疾病等级之间没有相关性,II级β= -0.0012 (95% CI, -0.0074 to 0.0049) (p = 0.64),III级β= -0.0006 (95% CI, -0.0056 to 0.0045) (p = 0.79),IV级β= 0.0025 (95% CI, -0.0075 to 0.0124)。然而,在IV级疾病比例较高的患者群体中观察到复发率增加的趋势:结论:对于痔疮患者来说,ALTA硬化疗法可能是一种安全可行的替代疗法。长期随访和高质量的随机对照试验将有助于确定 ALTA 硬化剂注射疗法在痔疮治疗中的地位。
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引用次数: 0
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Acta Chirurgica Belgica
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