Acta otorrinolaringologica espanola最新文献_第5页

Pediatric maxillary expansion to treat nasal obstruction 小儿上颌扩张术治疗鼻塞

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-05-01 DOI: 10.1016/j.otorri.2025.512220

Christian Calvo-Henriquez , Pedro Martínez-Seijas , Antonino Maniaci , Juan Carlos Pérez-Varela , Sandra Kahn , Isam Alobid , Stanley Y. Liu

Objective

An often neglected cause of nasal obstruction is maxillary constriction. Maxillary expansion (ME) has been proven to decrease nasal resistance and increase nasal volume and airflow thus improving nasal obstruction symptoms both in adults and children. However, up to the present, studies have reported on patients with an orthodontic indication for ME, but not being treated for nasal obstruction. In this study we report a case series of pediatric patients who have been diagnosed with nasal obstruction attributed to maxillary constriction and who have been treated with ME.

Methods

Participants were consecutively selected. All children performed anterior active rhinomanometry and SN-5 questionnaire before and after ME. The longest follow-up visit to otolaryngology was recorded for this study. The inclusion criteria were children without adenoid or turbinate enlargement with persistent oral breathing and nasal obstruction confirmed through rhinomanometry. All included children were referred to their odontologist who performed ME only if it was safe for the patient.

Results

23 participants with a mean age of 10.1 (range 6.66–13.27) were included. 78.3% had been previously submitted to surgery to restore or improve nasal breathing. There was a mean decrease in nasal resistance of 0.13 Pa s/cm³, which is a reduction of 34.2% over the mean initial value (P < .001). There was a statistically significant correlation between the amount of expansion and the decrease in nasal resistance (Rho = 0.75; P < .001), and the increase in nasal airflow (rho = 0.71; P < .001). Participants demonstrated a statistically significant decrease in their nasal symptoms measured with the SN5 questionnaire (P = .033).

Conclusions

These are preliminary results that should be managed with caution. Considering previous reports which included ME performed for orthodontic reasons, and the case series herein presented, which includes ME performed for nasal breathing, it seems that ME could be used with this latter objective. Future controlled studies should corroborate these results before producing a general recommendation.

目的上颌缩窄是鼻塞的一个常被忽视的原因。上颌扩张（ME）已被证明可以减少鼻阻力，增加鼻容积和气流，从而改善成人和儿童的鼻塞症状。然而，到目前为止，研究已经报道了ME的正畸指征患者，但没有治疗鼻塞。在这项研究中，我们报告了一系列被诊断为上颌缩窄引起的鼻塞并接受ME治疗的儿科患者的病例。方法连续选取受试者。所有患儿在ME前后均行前路主动鼻压测量和SN-5问卷调查。本研究记录了耳鼻喉科最长的随访时间。纳入标准为无腺样体或鼻甲肿大、持续口腔呼吸和鼻塞的儿童，经鼻测压证实。所有纳入的儿童都被转介到他们的齿科医生那里，只有在对患者安全的情况下才进行ME手术。结果共纳入23例参与者，平均年龄为10.1岁（范围6.66-13.27）。78.3%的患者曾接受过手术以恢复或改善鼻腔呼吸。鼻阻力平均下降0.13 Pa s/cm3，比平均初始值下降34.2% （P <； .001）。扩张量与鼻阻力下降有统计学意义(Rho = 0.75；P <； .001)，鼻气流增加(rho = 0.71；P & lt; 措施)。SN5问卷调查显示，受试者的鼻部症状有统计学意义的显著减少（P = .033）。结论这些都是初步结果，应谨慎处理。考虑到以前的报道中包括因正畸原因进行的ME，以及本文提出的病例系列，其中包括因鼻腔呼吸进行的ME，似乎ME可以用于后一种目的。在提出一般性建议之前，未来的对照研究应证实这些结果。

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引用次数: 0

Cochleo-vestibular phenotype in patients with pathogenic variations in the ACTG1 gene ACTG1基因致病性变异患者的耳蜗-前庭表型

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-05-01 DOI: 10.1016/j.otorri.2025.512217

Rocío González-Aguado , Jaime Gallo-Terán , Eshter Onecha , Carmelo Morales-Angulo

Objective

This study aimed to investigate the prevalence of pathogenic, likely pathogenic, and variants of unknown significance in the ACTG1 gene among families with suspected bilateral sensorineural hearing loss of genetic origin. Additionally, the research aimed to elucidate the cochleovestibular phenotype of individuals carrying these variants.

Methods

A cohort of 365 unrelated families with sensorineural hearing loss participated in this study. Genetic analysis was conducted using Next-Generation Sequencing (NGS).

Results

The study identified c.94C>A and c.721G>A pathogenic variants in heterozygosity in the ACTG1 gene among three probands. Two of these cases exhibited an autosomal dominant inheritance pattern, while the third was a de novo variant. Additionally, three other family members underwent genetic and audiological evaluations. Onset of hearing loss typically occurred between the first and second decades of life, initially affecting high frequencies and gradually extending to all frequencies. Treatment with hearing aids yielded favourable outcomes in all cases.

Conclusions

Pathogenic variants in the ACTG1 gene were found to be rare in the studied population. Nonetheless, these variants should be considered in families presenting with postlingual bilateral sensorineural hearing loss, particularly when high-frequency hearing loss progressively worsens to profound levels.

目的探讨疑似双侧感音神经性听力损失的家庭中ACTG1基因的致病性、可能致病性和未知意义变异的流行情况。此外，该研究旨在阐明携带这些变异的个体的耳蜗前庭表型。方法对365个无血缘关系的感音神经性听力损失家庭进行研究。采用新一代测序（NGS）进行遗传分析。结果在3个先证者中发现了ACTG1基因杂合性的c.94C>；A和c.721G>；A致病性变异。其中两例表现为常染色体显性遗传模式，而第三例为新生变异。此外，另外三名家庭成员接受了遗传和听力学评估。听力损失通常发生在生命的第一个和第二个十年之间，最初影响高频，逐渐扩展到所有频率。在所有病例中，助听器治疗都取得了良好的结果。结论ACTG1基因致病性变异在研究人群中罕见。尽管如此，在出现语后双侧感音神经性听力损失的家庭中，特别是当高频听力损失逐渐恶化到深度水平时，应该考虑这些变异。

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引用次数: 0

Consenso de la SEORL-CCC sobre la nomenclatura de los vaciamientos ganglionares cervicales 欧洲经委会-欧洲经委会关于子宫颈节律命名法的共识

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-05-01 DOI: 10.1016/j.otorri.2025.512231

Laura Rodrigáñez , Alexander Sistiaga , Fernando López , Eduardo Ferrandis , Pedro Diaz de Cerio , Pablo Parente , Alejandro Castro , Javier Gavilán

There have been multiple classifications of cervical dissections for decades in the literature, but none of them has been completely imposed worldwide. After an exhaustive review of them, the Oncology and Head and Neck Surgery Commission of the SEORL-CCC has agreed on its own classification to standardize neck dissections to be able to compare results.

The Oncology and Head and Neck Surgery Commission of the SEORL-CCC considers that cervical dissections should be classified according to the type of surgical approach performed (functional or radical) and its extension pursuant to the anatomical areas dissected (comprehensive or selective).

几十年来，文献中对颈椎解剖有多种分类，但没有一种分类在世界范围内被完全采用。在对它们进行了详尽的审查后，美国肿瘤和头颈外科委员会（SEORL-CCC）已经同意了自己的分类，以标准化颈部解剖，以便比较结果。SEORL-CCC的肿瘤学和头颈外科委员会认为，颈椎解剖应根据手术入路的类型（功能性或根治性）进行分类，并根据解剖区域（全面或选择性）进行扩展。

引用次数: 0

Improving voice quality in laryngectomy patients with botulinum toxin A 改善A型肉毒杆菌毒素喉切除术患者的语音质量

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-05-01 DOI: 10.1016/j.otorri.2025.512222

Gonçalo Caetano , Filipa Morgado , Joana Póvoa , Francisco Branquinho

Introduction

Tracheoesophageal (TEP) speech is the main voice rehabilitation method following laryngectomy. Pharyngoesophageal hypertonicity is one of the main causes for failure to achieve tracheoesophageal speech after laryngectomy. Botulinum toxin A (BTA) has been used to chemically denervate the pharyngeal musculature, and is an alternative to invasive surgical procedures. The aim of this work is to study the effectiveness and safety of this procedure.

Material & methods

A retrospective cohort study from 2019 to 2023 was performed of 20 patients with failure to achieve a functional tracheoesophageal voice following laryngectomy. These patients undergone local pharyngoesophageal segment BTA injection. A total of 100 units of BTA were injected at 6 different sites, 3 in each side.

Perceptual ratings of voice quality were performed before and 72 h after BTA injection by a speech therapist using a 7-point equal-appearing interval scale.

Results

Speech quality mean rating (μ) improved from 2.05 before to 4.55 after BTA injection (P = .004), 17 (85%) patients had an improvement in postinjection perceptual TEP speech quality ratings, with scores in the good-to-excellent range (5–6 in the 7-point equal-appearing interval scale) in 12 patients (60%).

Three patients (15%) didn’t improve their voice quality, two of them with no discernible TEP speech.

No adverse effects were reported.

Conclusions

The majority of the patients enrolled in this study (85%) showed an improvement in TEP speech following BTA injection. This is a safe and effective method to improve TEP speech following laryngectomy.

前言气管食管（TEP）语音是喉切除术后主要的语音康复方法。咽食道高张力是喉切除术后气管食道言语不能实现的主要原因之一。肉毒毒素A （BTA）已被用于化学去神经咽肌肉组织，是一种替代侵入性手术程序。这项工作的目的是研究该程序的有效性和安全性。材料,方法对2019 - 2023年20例喉切除术后气管食管声带功能缺失患者进行回顾性队列研究。患者行咽食管段局部BTA注射。在6个不同部位注射100个单位BTA，每侧3个。在BTA注射前和注射后72 h，由语言治疗师使用7分均等间隔量表对语音质量进行感知评分。结果语音质量平均评分（μ）由注射BTA前的2.05分提高到注射后的4.55分（P = .004），17例（85%）患者注射后感知TEP语音质量评分改善，12例（60%）患者评分在良至优（7分等出现间隔量表5-6分）。3名患者（15%）的语音质量没有改善，其中2名患者没有明显的TEP语音。无不良反应报告。结论本研究中大多数患者（85%）在注射BTA后TEP言语改善。这是一种安全有效的改善TEP术后言语的方法。

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引用次数: 0

“Cochlear Implant in a Labyrinthine Facial Nerve Dehiscence” 人工耳蜗治疗迷宫式面神经破裂

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-05-01 DOI: 10.1016/j.otorri.2025.512226

Inés Tortajada Torralba , Santiago Almanzo , Carlos de Paula Vernetta

引用次数: 0

Comentario al artículo: «Absceso periamigdalino recurrente en adultos: incidencia y factores de riesgo en una cohorte prospectiva longitudinal» 对文章的评论：“成人扁桃体周复发性脓肿：前瞻性纵向队列中的发病率和危险因素”

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-05-01 DOI: 10.1016/j.otorri.2025.512233

Francisco Javier García-Callejo, Miguel Juantegui Azpilicueta

引用次数: 0

Effect of bariatric surgery in the treatment of obstructive sleep apnea in obese patients 减肥手术治疗肥胖患者阻塞性睡眠呼吸暂停的效果

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-05-01 DOI: 10.1016/j.otorri.2025.512221

Silvia Matarredona-Quiles , Marina Carrasco-Llatas , Paula Martínez-Ruíz de Apodaca , Jose Ángel Díez-Ares , Elena González-Turienzo , José Dalmau-Galofre

Purpose

To analyze the success rate of bariatric surgery in the treatment of obstructive sleep apnea (OSA) in obese patients and its related factors.

Methods

Longitudinal, prospective, single cohort study, with consecutive sampling including OSA patients aged 18–65 years intervened of bariatric surgery. An anamnesis regarding OSA, a complete upper airway (UA) exploration and a cardiorespiratory polygraphy (CRP) pre- and post-surgery were performed.

Results

Fifty-seven patients were included in this study. The overall surgical success and cure rates for bariatric surgery as a treatment for OSA were 61.4% and 52.6%, respectively. Factors predicting success were female sex (OR = 12.54; CI95% = 1.75–89.88, p = 0.012), age below 53 years old (OR = 7.24; CI95% = 1.48–35.51, p = 0.015) and pre-surgical weight below 105 kg (OR = 8.1; CI95% = 1.44–45.62, p = 0.018). Surgical success cases had lower weight and body mass index, greater weight loss, smaller postsurgical neck circumference and less palatal webbing, however these were not independent factors in the multivariate analysis.

Conclusions

Our results show that bariatric surgery is a feasible option for OSA treatment in obese patients, with a higher success rate in female, younger and thinner patients. Moreover, adipose tissue on the UA has been proven to decrease as a result of weight loss, although not correlated with surgery success in the treatment of OSA.

目的分析减肥手术治疗肥胖患者阻塞性睡眠呼吸暂停（OSA）的成功率及其相关因素。方法采用纵向、前瞻性、单队列研究，连续抽样18 ~ 65岁OSA患者进行减肥手术干预。对OSA进行回顾性分析，术前和术后进行全上气道探查和心肺多导图（CRP）检查。结果共纳入57例患者。减肥手术治疗OSA的总体手术成功率和治愈率分别为61.4%和52.6%。预测成功的因素为女性(OR = 12.54；CI95% = 1.75 ~ 89.88, p = 0.012)，年龄小于53岁(OR = 7.24；CI95% = 1.48 ~ 35.51, p = 0.015)，术前体重小于105 kg (OR = 8.1；CI95% = 1.44-45.62, p = 0.018)。手术成功的患者体重和体质指数较低，体重减轻幅度较大，术后颈围较小，腭带较少，但这些不是多因素分析中的独立因素。结论肥胖患者手术治疗OSA是一种可行的选择，女性、年轻、瘦弱患者手术成功率较高。此外，UA上的脂肪组织已被证明由于体重减轻而减少，尽管与OSA治疗的手术成功无关。

{"title":"Effect of bariatric surgery in the treatment of obstructive sleep apnea in obese patients","authors":"Silvia Matarredona-Quiles , Marina Carrasco-Llatas , Paula Martínez-Ruíz de Apodaca , Jose Ángel Díez-Ares , Elena González-Turienzo , José Dalmau-Galofre","doi":"10.1016/j.otorri.2025.512221","DOIUrl":"10.1016/j.otorri.2025.512221","url":null,"abstract":"<div><h3>Purpose</h3><div>To analyze the success rate of bariatric surgery in the treatment of obstructive sleep apnea (OSA) in obese patients and its related factors.</div></div><div><h3>Methods</h3><div>Longitudinal, prospective, single cohort study, with consecutive sampling including OSA patients aged 18–65 years intervened of bariatric surgery. An anamnesis regarding OSA, a complete upper airway (UA) exploration and a cardiorespiratory polygraphy (CRP) pre- and post-surgery were performed.</div></div><div><h3>Results</h3><div>Fifty-seven patients were included in this study. The overall surgical success and cure rates for bariatric surgery as a treatment for OSA were 61.4% and 52.6%, respectively. Factors predicting success were female sex (OR = 12.54; CI95% = 1.75–89.88, p = 0.012), age below 53 years old (OR = 7.24; CI95% = 1.48–35.51, p = 0.015) and pre-surgical weight below 105 kg (OR = 8.1; CI95% = 1.44–45.62, p = 0.018). Surgical success cases had lower weight and body mass index, greater weight loss, smaller postsurgical neck circumference and less palatal webbing, however these were not independent factors in the multivariate analysis.</div></div><div><h3>Conclusions</h3><div>Our results show that bariatric surgery is a feasible option for OSA treatment in obese patients, with a higher success rate in female, younger and thinner patients. Moreover, adipose tissue on the UA has been proven to decrease as a result of weight loss, although not correlated with surgery success in the treatment of OSA.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 3","pages":"Article 512221"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relación de la infección por el virus del papiloma humano con la aparición de segundas neoplasias y su repercusión pronóstica en los pacientes con carcinoma de orofaringe 人乳头状瘤病毒感染与第二种肿瘤发生的关系及其对口咽癌患者的预后影响

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-05-01 DOI: 10.1016/j.otorri.2025.512237

Julia Gayà , David Rubio , Cristina Valero , Cristina Vázquez-López , Anna Holgado , Miquel Quer , Xavier León

Introduction

This study analyzes the incidence of second neoplasms in patients with oropharyngeal carcinoma according to human papillomavirus (HPV) status and its impact on survival.

Material and methods

A retrospective analysis of 583 patients with oropharyngeal cancer treated between 1991 and 2023 was performed. A total of 112 patients (19.2%) had HPV-positive tumors.

Results

During the follow-up, 181 patients (31.0%) had a second neoplasm. The 5-year and 10-year second neoplasm-free survival for HPV-negative patients were 60.5% and 37.5%, significantly lower than in HPV-positive patients, which were 88.2% and 70.8%, respectively (P =.0001). The 84.4% of second and subsequent neoplasms in HPV-negative patients occurred in locations associated with tobacco and alcohol use, compared to 65.5% in HPV-positive patients (P=.001). In comparison to HPV-positive patients with no history of toxics consumption, HPV-positive patients with severe toxics consumption had a significantly higher risk of second neoplasms in locations associated with tobacco and alcohol use (P =.003). The competitive mortality associated with the appearance of second and subsequent neoplasms was significantly higher for patients with HPV-negative tumors (P =.0001).

Conclusions

Patients with HPV-positive oropharyngeal carcinomas have a lower risk of second neoplasms and lower competitive mortality associated with the appearance of second neoplasms compared with HPV-negative patients.

本研究根据人乳头瘤病毒（HPV）状态分析口咽癌患者第二肿瘤的发生率及其对生存的影响。材料与方法对1991 ~ 2023年间583例口咽癌患者的临床资料进行回顾性分析。112例（19.2%）患者有hpv阳性肿瘤。结果随访期间，181例（31.0%）出现第二肿瘤。hpv阴性患者的5年和10年二次无瘤生存率分别为60.5%和37.5%，显著低于hpv阳性患者的88.2%和70.8% （P = 0.0001）。hpv阴性患者中84.4%的第二次及后续肿瘤发生在与烟草和酒精使用相关的部位，而hpv阳性患者中这一比例为65.5% （P=.001）。与没有毒物消费史的hpv阳性患者相比，严重毒物消费的hpv阳性患者在与烟草和酒精使用相关的部位发生第二肿瘤的风险明显更高（P = 0.003）。hpv阴性肿瘤患者与第二肿瘤及后续肿瘤出现相关的竞争性死亡率显著较高（P = 0.0001）。结论与hpv阴性患者相比，hpv阳性口咽癌患者发生第二肿瘤的风险较低，与第二肿瘤出现相关的竞争性死亡率较低。

{"title":"Relación de la infección por el virus del papiloma humano con la aparición de segundas neoplasias y su repercusión pronóstica en los pacientes con carcinoma de orofaringe","authors":"Julia Gayà , David Rubio , Cristina Valero , Cristina Vázquez-López , Anna Holgado , Miquel Quer , Xavier León","doi":"10.1016/j.otorri.2025.512237","DOIUrl":"10.1016/j.otorri.2025.512237","url":null,"abstract":"<div><h3>Introduction</h3><div>This study analyzes the incidence of second neoplasms in patients with oropharyngeal carcinoma according to human papillomavirus (HPV) status and its impact on survival.</div></div><div><h3>Material and methods</h3><div>A retrospective analysis of 583 patients with oropharyngeal cancer treated between 1991 and 2023 was performed. A total of 112 patients (19.2%) had HPV-positive tumors.</div></div><div><h3>Results</h3><div>During the follow-up, 181 patients (31.0%) had a second neoplasm. The 5-year and 10-year second neoplasm-free survival for HPV-negative patients were 60.5% and 37.5%, significantly lower than in HPV-positive patients, which were 88.2% and 70.8%, respectively (<em>P</em> =.0001). The 84.4% of second and subsequent neoplasms in HPV-negative patients occurred in locations associated with tobacco and alcohol use, compared to 65.5% in HPV-positive patients (<em>P</em>=.001). In comparison to HPV-positive patients with no history of toxics consumption, HPV-positive patients with severe toxics consumption had a significantly higher risk of second neoplasms in locations associated with tobacco and alcohol use (<em>P</em> =.003). The competitive mortality associated with the appearance of second and subsequent neoplasms was significantly higher for patients with HPV-negative tumors (<em>P</em> =.0001).</div></div><div><h3>Conclusions</h3><div>Patients with HPV-positive oropharyngeal carcinomas have a lower risk of second neoplasms and lower competitive mortality associated with the appearance of second neoplasms compared with HPV-negative patients.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 3","pages":"Article 512237"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cross-cultural adaptation of the CRS-PRO questionnaire into Spanish CRS-PRO问卷在西班牙语中的跨文化改编

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-05-01 DOI: 10.1016/j.otorri.2025.512219

Juan Maza-Solano , Ainhoa García-Lliberós , Xenia Mota-Rojas , Andrea Barrios , Christian Calvo-Henríquez , Isam Alobid , Serafín Sánchez-Gómez , Leigh J Sowerby

Background

Chronic rhinosinusitis (CRS) is a prevalent disease responsible for significant morbidity. Diagnostic criteria are well established but response to clinical and surgical treatment need greater consistency. The objective of this paper was to perform a cross-cultural adaptation of the CRS-PRO to the Spanish language for its use as a routine questionnaire in the evaluation of CRS.

Methods

The CRS-PRO questionnaire was translated using a three-step procedure in 50 patients, following the recommendations of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Native speakers of both European and South American Spanish participated in the translation.

Results

Of the initial 12 items, 4 were discordant among the three translators before a consensus was reached (Step 1). The item “breathe through the nose” (1/12) did not match between the back translation and the initial version of the CRS-PRO (Step 2). Step 3 generated a final revised Spanish version of the CRS-PRO. Fifty patients (average age 51.1, 48% male) completed the questionnaire. Significant gender differences were found in responses to “My face hurt” (P = .043). Significant differences in “My face hurt” also appeared for those completing the questionnaire in less than 80 s (P = .047). Differences in “problems with smell” (P = .039) were noted between chronic rhinosinusitis with and without polyposis.

Conclusion

This study presents the validated and Spanish-adapted version of the CRS-PRO questionnaire to evaluate CRS symptoms in the Spanish-speaking population.

背景：慢性鼻窦炎（CRS）是一种发病率很高的常见病。诊断标准已经建立，但对临床和手术治疗的反应需要更大的一致性。本文的目的是对CRS- pro进行跨文化改编，使其成为评估CRS的常规问卷。方法按照国际药物经济学与结果研究学会（ISPOR）的建议，采用三步程序对50例患者进行CRS-PRO问卷的翻译。以欧洲和南美西班牙语为母语的人都参与了翻译。在最初的12个项目中，在达成共识之前，三位翻译人员之间有4个不一致（步骤1）。“用鼻子呼吸”一项（1/12）与CRS-PRO初始版本（步骤2）不匹配。步骤3生成CRS-PRO的最终西班牙语修订版。50例患者（平均年龄51.1岁，男性48%）完成问卷调查。在“我的脸疼”的回答中发现了显著的性别差异（P = .043）。在“我的脸受伤了”这一问题上，在少于80 秒内完成问卷的人也出现了显著差异（P = .047）。慢性鼻窦炎伴和不伴息肉病的患者在“嗅觉问题”方面存在差异（P = .039）。结论本研究采用经验证的西班牙语版CRS- pro问卷来评估西班牙语人群的CRS症状。

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引用次数: 0

ENT pediatric infection diseases and its relationship with COVID-19. Results of a retrospective cohort study in Madrid, Spain 小儿耳鼻喉科感染及其与新冠肺炎的关系西班牙马德里一项回顾性队列研究的结果

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-05-01 DOI: 10.1016/j.otorri.2025.512225

Montserrat Asensi-Diaz, Monica Hernando Cuñado, Alex Lowy Benoliel, Juan Antonio Pasamontes Pingarron, Carlos Martin-Oviedo, Rosalia Souviron Encabo, Maria Scola Torres, Miguel Aristegui

Introduction

During the COVID-19 pandemic, ENT infections decreased but became more severe when combined with COVID-19. Post-pandemic, there has been a notable rise in ENT infections globally, particularly ear infections. In our region, we observed an increase in complicated pediatric ENT infections requiring urgent surgical intervention after the end of preventive measures. This study investigates the changes in ENT infection profiles in Madrid, Spain, following the pandemic.

Material and methods

We analyzed data from children who underwent urgent ENT surgical interventions at a Spanish tertiary hospital between January 2018 and December 2023. The data was divided into three groups: pre-pandemic (1st group), during the pandemic with preventive measures (2nd group), and post-pandemic after the removal of these measures (3rd group). Variables included demographics, clinical data, imaging, treatment, and hospitalization duration.

Results

The study involved 87 children (58.6% male) with a mean age of 6.4 years. There was a significant overall increase in ENT infections in the 3rd group compared to the 1st and 2nd groups (p = 0.036). Specifically, ear infections increased significantly after the removal of social measures (p = 0.033). In the 3rd group, Streptococcus pyogenes infections increased (p = 0.028), with Amoxicillin becoming the predominant treatment (p = 0.047), as opposed to Amoxicillin-clavulanic acid used for Fusobacterium in earlier periods (p = 0.00).

Discussion and conclusion

The pandemic has shifted the ENT infection profile, with increased ear infections and a rise in Group A streptococcus post-pandemic. This underscores the need for updated treatment strategies for pediatric ENT infections.

在2019冠状病毒病大流行期间，耳鼻喉科感染有所下降，但与COVID-19合并后变得更加严重。大流行后，全球耳鼻喉科感染，特别是耳部感染显著上升。在我们的地区，我们观察到在预防措施结束后需要紧急手术干预的复杂儿科耳鼻喉感染的增加。本研究调查了大流行后西班牙马德里耳鼻喉科感染概况的变化。材料和方法我们分析了2018年1月至2023年12月在西班牙一家三级医院接受紧急耳鼻喉外科手术干预的儿童的数据。数据分为三组：大流行前（第一组）、大流行期间采取预防措施（第二组）和大流行后取消这些措施（第三组）。变量包括人口统计学、临床资料、影像学、治疗和住院时间。结果共纳入87例儿童，其中男性58.6%，平均年龄6.4岁。与第1组和第2组相比，第3组耳鼻喉科感染的总体发生率显著增加（p = 0.036）。具体而言，耳部感染在取消社交措施后显著增加（p = 0.033）。在第三组中，化脓性链球菌感染增加（p = 0.028），阿莫西林成为主要的治疗方法（p = 0.047），而阿莫西林-克拉维酸在早期用于梭杆菌（p = 0.00）。讨论与结论大流行改变了耳鼻喉科感染概况，大流行后耳部感染增加，a群链球菌感染增加。这强调了更新儿科耳鼻喉科感染治疗策略的必要性。

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引用次数: 0