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Intraoral ultrasonography: an adjunct in oral onco-surgery 口腔内超声波检查:口腔黏膜手术的辅助手段
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.otorri.2024.01.006
Divyanshi Singh , Neeti Aggarwal , Ravinder S Minhas , Ramesh K Azad , MS Vasanthalakshmi , Jagdeep S Thakur

Objective

To determine the precision and accuracy of intraoral sonography in assessing the depth of invasion in oral cancer.

Material and methods

A prospective study was conducted in 30 cases of oral cancer. Subjects were subjected to computerised tomography and intraoral sonography before surgery. The depth of invasion assessed through clinical palpation and radiological tools was compared with surgical histopathology.

Results

The depth of invasion assessed on clinical palpation and computerized tomography had statistically significant difference with histopathology whereas intraoral sonography didn’t show any difference. The intraoral sonography and computerised tomography had comparable precision and accuracy, with a slight dominance of the computerised tomography in assessing the tumor's depth of invasion greater than 4 mm. However, intraoral sonography was more precise and accurate than computerised tomography in assessing the depth of invasion beyond 10 mm.

Conclusion

Intraoral sonography was found to be a reliable tool in the assessment of the depth of invasion in oral cancer. It can prove beneficial during surgery in achieving tumour-free surgical margins.

材料和方法 对 30 例口腔癌患者进行了前瞻性研究。受试者在手术前接受计算机断层扫描和口腔内超声波检查。结果临床触诊和计算机断层扫描所评估的侵犯深度与组织病理学有显著统计学差异,而口内超声波检查则无任何差异。口腔内声学造影和计算机断层扫描的精确度和准确性相当,在评估肿瘤侵犯深度大于 4 毫米时,计算机断层扫描略占优势。结论口腔超声造影是评估口腔癌浸润深度的可靠工具。结论口腔内声学造影被认为是评估口腔癌侵犯深度的可靠工具,在手术过程中有助于实现无肿瘤手术切缘。
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引用次数: 0
The association of bacterial biofilm and middle ear mucosa in patients with mucosal chronic suppurative otitis media 粘膜慢性化脓性中耳炎患者的细菌生物膜与中耳粘膜的关系
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-07-01 DOI: 10.1016/j.otorri.2024.02.003
Nahla Nosair , Saad Elzayat , Radwa Elsharaby , Ibrahim A. Abdulghaffar , Haitham H. Elfarargy , Nehal A. Sharaf

Objectives

To evaluate the bacterial biofilm’s role in mucosal chronic suppurative otitis media (CSOM) utilizing scanning electron microscopy (SEM).

Methods

This study involved 123 participating patients with active and inactive mucosal CSOM who underwent tympanomastoid surgery. SEM was used to examine middle ear mucosa biopsies for the development of biofilms. Middle ear discharge or mucosal swabs from patients were cultured to detect any bacterial growth. The biofilm formation was correlated to the culture results.

Results

The biofilm was present in 69.9 % of patients (59% of them were with active mucosal CSOM) and absent in 30.1% of the patients (70% of them were with inactive mucosal CSOM), being more statistically significant in active mucosal CSOM (p-value = 0.003). A correlation that was statistically significant was found between active mucosal CSOM and higher grades (3 and 4) of biofilms (p-value <0.05). The mucosal CSOM type and the results of the culture had a relationship that was statistically significant (p-value <0.001). 60% of patients had positive culture (70% of them were with active mucosal CSOM). There was a statistically significant relation between Pseudomonas aeruginosa bacterial growth and active mucosal CSOM (p-value = 0.004) as well as higher grades of biofilms in mucosal CSOM.

Conclusion

Mucosal CSOM, especially the active type, is a biofilm-related disease. There is a significant relation between the state of mucosal CSOM (active or inactive) and culture results with predominance of Pseudomonas aeruginosa bacterial growth in active mucosal CSOM and in higher grades of biofilms in mucosal CSOM.

目的利用扫描电子显微镜(SEM)评估细菌生物膜在粘膜慢性化脓性中耳炎(CSOM)中的作用。方法本研究涉及 123 名接受鼓室手术的活动性和非活动性粘膜 CSOM 患者。扫描电子显微镜用于检查中耳粘膜活检组织是否出现生物膜。对患者的中耳分泌物或粘膜拭子进行培养,以检测是否有细菌生长。结果69.9%的患者(其中59%为活动性粘膜 CSOM)存在生物膜,30.1%的患者(其中70%为非活动性粘膜 CSOM)不存在生物膜,其中活动性粘膜 CSOM 的生物膜形成具有更显著的统计学意义(p 值 = 0.003)。活动性粘膜 CSOM 与生物膜等级较高(3 级和 4 级)之间存在统计学意义上的相关性(p 值为 0.05)。粘膜 CSOM 类型与培养结果之间的关系具有统计学意义(p 值为 0.001)。60%的患者培养结果呈阳性(其中 70% 为活动性粘膜 CSOM)。铜绿假单胞菌细菌生长与活动性粘膜 CSOM(p 值 = 0.004)以及粘膜 CSOM 中生物膜等级较高之间存在统计学意义。粘膜 CSOM 的状态(活跃或不活跃)与培养结果之间有明显的关系,在活跃的粘膜 CSOM 中,铜绿假单胞菌的生长占主导地位,粘膜 CSOM 中生物膜的等级也较高。
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引用次数: 0
Vertical dorsal rhinotomy in pediatric nasal dermoid surgery 小儿鼻赘手术中的鼻背垂直切开术
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-07-01 DOI: 10.1016/j.otorri.2024.01.007
Pedro L. Alexandre , Gil Coutinho , Tiago Órfão , Pedro Marques , Jorge Spratley , Carla Pinto Moura

Introduction and objectives

Nasal dermoids are uncommon midline congenital lesions in the nose, usually diagnosed in the first years of life. Imaging is mandatory to evaluate local and intracranial extension and treatment consists in surgical excision. This study aims to review the experience of the department in managing pediatric nasal dermoids using a dorsal rhinotomy surgical approach.

Material and methods

Retrospective case series of pediatric nasal dermoids treated at a tertiary university teaching hospital over a period of seven years.

Results

Nine children were treated during this period. Clinical presentation was a dermoid sinus-cyst in seven cases and a cystic lesion in two. Pre-operative imaging revealed extension of the lesion to the foramen cecum in three cases. Surgery was performed via vertical dorsal rhinotomy in all patients, and associated endoscopic surgery was used in three patients. Reconstruction with autologous material was performed in three cases. No complications or recurrences were registered during the follow-up.

Conclusions

In the presented series, a vertical dorsal rhinotomy incision has provided good functional and aesthetic results. The possibility of nasal dermoid intracranial extension should be accessed with imaging but remains uncommon. In its absence, this approach may be useful and can be paired with other techniques, such as nasal endoscopy, to achieve the best outcomes.

导言和目的:鼻腔蝶窦是一种不常见的鼻腔中线先天性病变,通常在患者出生后的头几年被诊断出来。必须进行影像学检查以评估局部和颅内扩展情况,治疗方法包括手术切除。本研究旨在回顾该科室采用鼻背切开手术方法治疗小儿鼻赘的经验。材料和方法在一家三级大学教学医院治疗小儿鼻赘的回顾性病例系列,历时七年。临床表现为7例为鼻腔蝶窦囊肿,2例为囊性病变。术前造影显示,3 例病变扩展至盲肠孔。所有患者的手术都是通过鼻背垂直切开术进行的,有三名患者采用了相关的内窥镜手术。三例患者使用自体材料进行了重建。在随访过程中未发现并发症或复发。应通过影像学检查了解鼻赘颅内扩展的可能性,但这种情况并不常见。如果没有这种情况,这种方法可能是有用的,可以与鼻内窥镜等其他技术搭配使用,以达到最佳效果。
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引用次数: 0
Comentarios sobre el artículo: Rendimiento diagnóstico del estudio genético en adultos con hipoacusia neurosensorial 关于文章的评论:感音神经性听力损失成人患者基因检测的诊断性能
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-07-01 DOI: 10.1016/j.otorri.2023.12.003
Carmelo Morales-Angulo , Patricia Corriols-Noval
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引用次数: 0
Disease-free survival and response to therapy of clinically node- negative papillary thyroid cancer treated without central neck dissection: Retrospective study of 321 patients 临床结节阴性甲状腺乳头状癌的无病生存期和对治疗的反应:321例患者的回顾性研究
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-07-01 DOI: 10.1016/j.otorri.2024.01.004
Carmen Ruiz-García , Laura Rodrigáñez Riesco , Blanca Mateos-Serrano , Ricardo Bernáldez Millán , Antonio J Del Palacio Muñoz , Javier Gavilán , Paola Parra Ramírez , Patricia Martín-Rojas Marcos , Arturo Lisbona Catalán , Beatriz Lecumberri , Cristina Álvarez-Escolá , Alejandro Castro

Background and objective

Nodal metastases in the central compartment are frequent in papillary thyroid cancer (PTC). However, they are mostly micrometastases with no impact on survival and their relevance on the risk of locoregional relapse is controversial.

There is no consensus regarding optimal management of the central neck in patients with PTC cN0. In our center, we do not perform prophylactic central neck dissection (pCND). The objective of this study is to review our long-term results and compare them with the most recent literature.

Patients and methods

Retrospective review of patients with PTC who underwent total thyroidectomy (TT) without CND between 2005 and 2017. Primary result was disease-free survival in the neck (DFS).

Results

321 patients were identified, mostly T1-T2 tumors (94.1%). Median follow-up was 90 months. DFS in the central compartment was excellent (96.1% at 10 year’s follow-up). 19 patients had cervical recurrence, of which 15 underwent salvage surgery.

On their last visit, including salvage surgery when appropriate, 77% of patients had excellent response, 18.7% had indeterminate response, 3.1% had biochemically incomplete response and 1.2% had morphologically incomplete response. Recurrent laryngeal nerve (RLN) paralysis after TT was transient in 4.7% of patients and permanent in 0.9% of patients. There were no RLN paralysis after salvage surgery. Permanent hypoparathyroidism occurred in 3.4% of patients. Only one patient had hypoparathyroidism after salvage surgery and it was permanent.

Conclusions

Based on long-term results and low rate of complications associated with salvage surgery in our experience, we consider routine pCND is not justified.

背景和目的甲状腺乳头状癌(PTC)经常出现中央区结节转移。然而,这些转移灶大多是微转移灶,对患者的生存没有影响,而且它们与局部复发风险的相关性也存在争议。在我们中心,我们不进行预防性颈部中央切除术(pCND)。本研究的目的是回顾我们的长期结果,并将其与最新文献进行比较。患者和方法回顾性研究2005年至2017年间接受全甲状腺切除术(TT)而未进行CND的PTC患者。主要结果为颈部无病生存期(DFS)。结果共发现 321 例患者,大部分为 T1-T2 肿瘤(94.1%)。中位随访时间为90个月。中央区的无病生存率非常好(10年随访时为96.1%)。在最后一次就诊时,包括适当的挽救手术在内,77%的患者反应良好,18.7%的患者反应不确定,3.1%的患者生化反应不完全,1.2%的患者形态反应不完全。4.7%的患者在TT后出现短暂的喉返神经(RLN)麻痹,0.9%的患者出现永久性麻痹。抢救性手术后没有出现喉返神经麻痹。3.4%的患者出现永久性甲状旁腺功能减退。只有一名患者在抢救手术后出现了甲状旁腺功能减退,而且是永久性的。结论根据我们的经验,抢救手术的长期效果和并发症发生率都很低,因此我们认为常规的pCND并不合理。
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引用次数: 0
Posterior semicircular canal involvement in sudden hearing loss 突发性听力损失中的后半规管受累问题
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-07-01 DOI: 10.1016/j.otorri.2024.01.002
Elena Dina , Mario Prenafeta Moreno , Àngels Martínez Arias
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引用次数: 0
Comparación técnica Minimal Invasive Ponto Surgery (MIPS) versus incisión lineal con preservación de tejidos en los implantes osteointegrados modelo Ponto® 骨结合 Ponto® 模型植入物的微创 Ponto 手术 (MIPS) 技术与保留组织的线性切口的比较
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-07-01 DOI: 10.1016/j.otorri.2023.10.008
Carmen Fernández-Cedrón Bermejo, Elena Sánchez Fernández, María Costales Marcos, Faustino José Núñez Batalla, José Luis Llorente Pendás, Justo Ramón Gómez Martínez

Background and objectives

The surgery of osseointegrated implants has undergone different modifications over the years with the aim of achieving better results and facilitating the surgical technique. Today the most commonly used technique is the linear incision with tissue preservation and placement of the abutment and implant. The long-term success of this technique has served as the basis for the development of the so-called minimally invasive surgical approach (MIPS). This study compares the short-, medium- and long-term results between the classic linear incision technique and the MIPS technique.

Material and methods

A prospective study was conducted on patients who had an osseointegrated implant placed between February 2016 and February 2020. A total of 59 surgeries were performed, 32 surgeries according to the linear incision technique with tissue preservation and 27 with MIPS technique. Outcomes were evaluated at 1 week, 1 month and 1 year.

Results

Statistically significant differences were achieved between the two groups at 1 week after surgery. Eighty percent of the MIPS patients had Holgers grades 0–1 compared to 35% of the linear technique patients (p = 0.001). No statistically significant differences were observed at 1 month (p = 0.457) and 1 year (p = 0.228). One case with grade 4 was recorded which resulted in implant extrusion one month after surgery with the MIPS technique. A new osseointegrated implant was placed 2 months after the fall using the same MIPS technique with good results. We were also able to verify that the duration of surgery was much shorter with the MIPS technique and better tolerated in terms of postoperative discomfort by the patient.

Conclusions

In our experience, the MIPS technique is the technique of choice for surgery of osseointegrated Ponto model implants as it is simpler, faster and presents fewer problems in the immediate postoperative period, with similar long-term postoperative results.

背景和目的多年来,为了获得更好的效果和简化手术技术,骨结合种植手术经历了不同的修改。目前最常用的技术是线性切口,同时保留组织并植入基台和种植体。这种技术的长期成功为所谓的微创手术方法(MIPS)的发展奠定了基础。本研究比较了经典线性切口技术和 MIPS 技术的短期、中期和长期效果。材料和方法对 2016 年 2 月至 2020 年 2 月期间植入骨结合种植体的患者进行了前瞻性研究。共进行了 59 例手术,其中 32 例采用了保留组织的线性切口技术,27 例采用了 MIPS 技术。结果两组患者在术后 1 周时差异有统计学意义。80%的 MIPS 患者的 Holgers 分级为 0-1,而 35% 的线性技术患者的 Holgers 分级为 0-1(P = 0.001)。在术后 1 个月(p = 0.457)和 1 年(p = 0.228),两组患者在统计学上没有明显差异。在使用 MIPS 技术进行手术一个月后,有一例 4 级病例导致种植体挤出。跌倒后 2 个月,我们采用同样的 MIPS 技术植入了新的骨结合种植体,效果良好。结论 根据我们的经验,MIPS 技术是骨结合 Ponto 模型种植体手术的首选技术,因为它更简单、快捷,术后即刻出现的问题更少,而且术后长期效果相似。
{"title":"Comparación técnica Minimal Invasive Ponto Surgery (MIPS) versus incisión lineal con preservación de tejidos en los implantes osteointegrados modelo Ponto®","authors":"Carmen Fernández-Cedrón Bermejo,&nbsp;Elena Sánchez Fernández,&nbsp;María Costales Marcos,&nbsp;Faustino José Núñez Batalla,&nbsp;José Luis Llorente Pendás,&nbsp;Justo Ramón Gómez Martínez","doi":"10.1016/j.otorri.2023.10.008","DOIUrl":"10.1016/j.otorri.2023.10.008","url":null,"abstract":"<div><h3>Background and objectives</h3><p>The surgery of osseointegrated implants has undergone different modifications over the years with the aim of achieving better results and facilitating the surgical technique. Today the most commonly used technique is the linear incision with tissue preservation and placement of the abutment and implant. The long-term success of this technique has served as the basis for the development of the so-called minimally invasive surgical approach (MIPS). This study compares the short-, medium- and long-term results between the classic linear incision technique and the MIPS technique.</p></div><div><h3>Material and methods</h3><p>A prospective study was conducted on patients who had an osseointegrated implant placed between February 2016 and February 2020. A total of 59 surgeries were performed, 32 surgeries according to the linear incision technique with tissue preservation and 27 with MIPS technique. Outcomes were evaluated at 1 week, 1 month and 1 year.</p></div><div><h3>Results</h3><p>Statistically significant differences were achieved between the two groups at 1 week after surgery. Eighty percent of the MIPS patients had Holgers grades 0–1 compared to 35% of the linear technique patients (<em>p</em> <!-->=<!--> <!-->0.001). No statistically significant differences were observed at 1 month (<em>p</em> <!-->=<!--> <!-->0.457) and 1 year (<em>p</em> <!-->=<!--> <!-->0.228). One case with grade 4 was recorded which resulted in implant extrusion one month after surgery with the MIPS technique. A new osseointegrated implant was placed 2 months after the fall using the same MIPS technique with good results. We were also able to verify that the duration of surgery was much shorter with the MIPS technique and better tolerated in terms of postoperative discomfort by the patient.</p></div><div><h3>Conclusions</h3><p>In our experience, the MIPS technique is the technique of choice for surgery of osseointegrated Ponto model implants as it is simpler, faster and presents fewer problems in the immediate postoperative period, with similar long-term postoperative results.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 4","pages":"Pages 210-216"},"PeriodicalIF":0.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139018219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The tortuous course of the anterior ethmoidal artery in the orbit: A cadaveric study 乙状前动脉在眼眶内的曲折走向:尸体研究
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-07-01 DOI: 10.1016/j.otorri.2023.12.001
Fulya Yaprak , Istemihan Coban , Mehmet Asım Ozer , Figen Govsa

Aim

The study aimed to define the coursing pattern of the anterior ethmoidal artery (AEA) in the orbit to minimize complications during endoscopic interventions.

Materials and methods

A total of ten formalin-fixed cadaveric halves were included in the study. Orbital regions were shown with a superior approach. The superior rectus and superior oblique muscles, as well as the connective tissue and vessels were removed to observe the path of the anterior ethmoidal artery. Measurements such as the width of the artery, the anterior-posterior length of the U formation, the length of the intraorbital part of the ophthalmic artery, and the distance of the AEA from its opthalmic origin to the anterior ethmoidal foramen were made.

Results

Ten of the AEAs originated from the ophthalmic artery. The AEA branches originated from the ophthalmic artery approximately 18.4 mm after the orbital artery entered the orbital, and the mean width of the AEAs was 0.82 mm. In seven of the total anterior ethmoidal arteries, they coursed in the intraethmoidal cavities below the cranial base. The mean distance from the origin of AEAs to the medial wall of the orbit was 4.9 mm. After leaving the ophthalmic artery, seven of the AEAs were coursing forward and turned back ('U' turn formation), which have proximately 1.5 mm in anteroposterior direction.

Conclusion

The anterior ethmoidal artery is 0.8 mm wide, originates from the distal part of the ophthalmic artery, entering the orbit after a 1.5 mm U-turn.

研究旨在确定乙状前动脉(AEA)在眼眶内的走向,以减少内窥镜介入治疗时的并发症。眼眶区域以上入路显示。切除上直肌和上斜肌以及结缔组织和血管,以观察乙状前动脉的路径。测量内容包括动脉的宽度、U形成的前后长度、眼动脉眶内部分的长度以及AEA从眼部起源到乙状前孔的距离。眼动脉进入眼眶后约18.4毫米处,AEA分支起源于眼动脉,AEA的平均宽度为0.82毫米。在所有乙状前动脉中,有 7 条流经颅底下方的乙状前腔。从乙状前动脉的起源到眼眶内侧壁的平均距离为 4.9 毫米。结论:乙状前动脉宽0.8毫米,起源于眼动脉的远端,经过1.5毫米的 "U "形转弯后进入眼眶。
{"title":"The tortuous course of the anterior ethmoidal artery in the orbit: A cadaveric study","authors":"Fulya Yaprak ,&nbsp;Istemihan Coban ,&nbsp;Mehmet Asım Ozer ,&nbsp;Figen Govsa","doi":"10.1016/j.otorri.2023.12.001","DOIUrl":"https://doi.org/10.1016/j.otorri.2023.12.001","url":null,"abstract":"<div><h3>Aim</h3><p>The study aimed to define the coursing pattern of the anterior ethmoidal artery (AEA) in the orbit to minimize complications during endoscopic interventions.</p></div><div><h3>Materials and methods</h3><p>A total of ten formalin-fixed cadaveric halves were included in the study. Orbital regions were shown with a superior approach. The superior rectus and superior oblique muscles, as well as the connective tissue and vessels were removed to observe the path of the anterior ethmoidal artery. Measurements such as the width of the artery, the anterior-posterior length of the U formation, the length of the intraorbital part of the ophthalmic artery, and the distance of the AEA from its opthalmic origin to the anterior ethmoidal foramen were made.</p></div><div><h3>Results</h3><p>Ten of the AEAs originated from the ophthalmic artery. The AEA branches originated from the ophthalmic artery approximately 18.4 mm after the orbital artery entered the orbital, and the mean width of the AEAs was 0.82 mm. In seven of the total anterior ethmoidal arteries, they coursed in the intraethmoidal cavities below the cranial base. The mean distance from the origin of AEAs to the medial wall of the orbit was 4.9 mm. After leaving the ophthalmic artery, seven of the AEAs were coursing forward and turned back ('U' turn formation), which have proximately 1.5 mm in anteroposterior direction.</p></div><div><h3>Conclusion</h3><p>The anterior ethmoidal artery is 0.8 mm wide, originates from the distal part of the ophthalmic artery, entering the orbit after a 1.5 mm U-turn.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 4","pages":"Pages 217-223"},"PeriodicalIF":0.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141582174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alta hospitalaria precoz mediante la predicción temprana del hipoparatiroidismo postiroidectomía 通过早期预测甲状腺切除术后甲状旁腺功能减退症实现提前出院
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-07-01 DOI: 10.1016/j.otorri.2023.12.004
Antonio Galindo Fernández , Ana Giribet Fernández-Pacheco , Nathalie Fages Cárceles , Laura Espinosa Fernández , Alba Molina Moreno , Francisco José García-Purriños García

Introduction

Hypoparathyroidism is the most common postsurgical complication of total thyroidectomy. Furthermore, it is the main cause of prolonged hospitalization after this procedure.

Objective

To predict the probability of post-thyroidectomy hypocalcemia according to the levels of intact parathyroid hormone (iPTH), as well as to determine the needs for treatment with exogenous calcium according to the levels of serum calcium (Ca).

Materials and methods

Retrospective study was carried out on patients who underwent total thyroidectomy between January 2017 and January 2020 at Los Arcos del Mar Menor University Hospital (HULAMM). iPTH and Ca levels were measured at 4, 24 and 48 hours after the surgery. Follow-up was 6 months.

Results

Ninety-four patients were operated on. Temporary and permanent postoperative hypoparathyroidism percentages were, respectively, 51.06% and 6.38%. PTHi level 24 hours after the procedure was the most reliable predictor of post-thyroidectomy temporary hypoparathyroidism (Area Under the ROC Curve (AUC)=0.933, P<.001). iPTH levels ≥ 29 pg/ml predicted normal parathyroid metabolism.

Conclusions

The combined values of iPTH and Ca levels 24 hours after thyroidectomy seems to be a reliable, safe and efficient method to control the post-thyroidectomy hypoparathyroidism. Our protocol could reduce the hospital stay of patients at low risk of hypocalcemia, allowing them to be discharged from the hospital on the first postoperative morning and identifying patients at high risk of hypocalcemia early.

导言甲状旁腺功能减退症是甲状腺全切除术后最常见的并发症,也是导致术后住院时间延长的主要原因。目的 根据完整甲状旁腺激素(iPTH)水平预测甲状腺切除术后低钙血症的概率,并根据血清钙(Ca)水平确定外源性钙治疗的需求。材料与方法对 2017 年 1 月至 2020 年 1 月期间在洛斯阿科斯德尔马梅诺尔大学医院(HULAMM)接受甲状腺全切除术的患者进行了回顾性研究,分别在术后 4、24 和 48 小时测量 iPTH 和 Ca 水平。结果94名患者接受了手术。术后暂时性和永久性甲状旁腺功能减退的比例分别为51.06%和6.38%。术后24小时PTHi水平是甲状腺切除术后暂时性甲状旁腺功能减退最可靠的预测指标(ROC曲线下面积(AUC)=0.933,P<.001)。iPTH水平≥29 pg/ml可预测甲状旁腺代谢正常。我们的方案可以缩短低钙血症低风险患者的住院时间,使他们在术后第一个早晨就能出院,并能及早发现低钙血症高风险患者。
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引用次数: 0
Adaptación y validación de la versión española del cuestionario NOSE-Perf para perforaciones septales 针对房间隔穿孔的 NOSE-Perf 问卷西班牙文版的改编和验证。
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-07-01 DOI: 10.1016/j.otorri.2024.01.008
Mireia Quer-Castells , Berta Alegre , María Jesús Rojas-Lechuga , Isam Alobid

Background and objective

Septal perforation (SP) cause heterogeneous symptoms depending on the anatomical location, highlighting scabs, nasal obstruction and/or epistaxis. The use of questionnaires to determine the quality of life in different pathologies is increasing in sinonasal pathologies and in patients with SP the NOSE-Perf questionnaire was constructed, currently validated in English. The aim of this study is the translation, cross-cultural adaptation, and validation of the NOSE-Perf questionnaire into Spanish.

Material and methods

Prospective single-center study of 81 patients (38 with SP and 43 controls), visited in the Rhinology section of a tertiary hospital. Adaptation and translation NOSE-Perf into Spanish and validation using the NOSE and NOSE-Perf questionnaire in Spanish.

Results

Significant differences were found in the mean NOSE-Perf score and in the mean NOSE score (95%CI: 21.2-26.9; P<.001 and 95%CI: 53.8-70.5; P<.001) between PS group and control group. Pearson's correlation between the two questionnaires NOSE-Perf and NOSE in the SP group was 0.74 (95%CI: 0.56-0.86; P<.001). In the control group it was r = 0.85 (95%CI: 0.73-0.91; P<.001). Cronbach's alpha coefficient of the NOSE-Perf was 0,95 (95%CI: 0,93-0.96) for internal consistency. The reliability evaluation was carried out by test-retest, and a strong Pearson correlation was obtained between the questionnaires r = 0.94 (95%CI: 0.85-0.97; P<.001) and r = 0.89 (95%CI: 0.77-0.95; P<.001).

Conclusions

The Spanish version of the NOSE-Perf is as reliable and valid as the English version, which makes it possible to assess the impact on quality of life that it causes in patients with perforations in the Spanish-speaking population.

背景和目的鼻窦穿孔(SP)会因解剖位置不同而引起不同的症状,突出表现为结痂、鼻塞和/或鼻衄。在鼻窦病变中,越来越多地使用调查问卷来确定不同病变的生活质量,并针对 SP 患者设计了 NOSE-Perf 问卷,该问卷目前已在英语国家得到验证。本研究的目的是将 NOSE-Perf 问卷翻译成西班牙语,并进行跨文化改编和验证。材料和方法对一家三甲医院鼻科就诊的 81 名患者(38 名 SP 患者和 43 名对照组患者)进行了单中心前瞻性研究。将 NOSE-Perf 改编和翻译成西班牙语,并使用西班牙语 NOSE 和 NOSE-Perf 问卷进行验证。结果发现 PS 组和对照组的 NOSE-Perf 平均得分和 NOSE 平均得分存在显著差异(95%CI:21.2-26.9;P<.001 和 95%CI:53.8-70.5;P<.001)。在 SP 组中,NOSE-Perf 和 NOSE 这两个问卷之间的皮尔逊相关性为 0.74 (95%CI: 0.56-0.86; P<.001)。对照组的相关系数为 r = 0.85 (95%CI: 0.73-0.91; P<.001)。NOSE-Perf 的内部一致性 Cronbach's alpha 系数为 0.95(95%CI:0.93-0.96)。结论西班牙文版 NOSE-Perf 与英文版一样可靠有效,因此可以评估其对西班牙语人群中穿孔患者生活质量的影响。
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引用次数: 0
期刊
Acta otorrinolaringologica espanola
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