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Decision-making in Petrous Bone Cholesteatoma (PBC): Surgical options according to PBC classification 岩质骨胆脂瘤(PBC)的决策:根据PBC分类的手术选择
IF 1.1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-01 DOI: 10.1016/j.otorri.2025.512277
Monica Rueda Vega , Montserrat Asensi-Diaz , Carolina López Granados , Carlos Martín Oviedo , Ignacio Arístegui Torrano , Miguel Arístegui Ruiz

Introduction

Petrous bone cholesteatoma (PBC) is a rare, potentially life-threatening condition requiring surgical management to prevent severe complications. While classification systems, such as Sanna’s, are widely used to guide surgical planning, actual decision-making is often influenced by additional clinical factors beyond lesion type.

Material and methods

A retrospective analysis of 94 PBCs in 92 patients operated between 1995 and 2024 was conducted. Data included demographics, clinical presentation, PBC classification, surgical approach, use of endoscopic assistance, recurrence, follow-up, and hearing rehabilitation. The aim of this study is to describe the surgical strategies applied to different PBC types in a series of 94 cases, evaluate the practical utility of classification systems, and propose a decision-making approach based on inner ear involvement and other critical factors

Results

The most common PBC type was supralabyrinthine (40.43%), followed by massive (18.09%) and retrolabyrinthine-infralabyrinthine (11.7%). A total of 102 surgeries were performed using various approaches, including modified translabyrinthine (24.51%), subtotal petrosectomy (22.55%), and transotic approach (18.63%). Endoscopic assistance was used in 11 cases. Recurrence occurred in 8.51% of cases, with a median follow-up of 48.5 months. Cochlear implantation was used in 8 patients and bone conduction implants in 3.

Conclusions

PBC classification provides valuable insights for understanding lesion behavior and planning surgery, but it is insufficient alone for determining the optimal surgical approach. Decisions must be individualized, considering hearing status, inner ear and facial nerve involvement, contralateral ear function, lesion extension, and anatomical factors. A classification-based strategy complemented by these considerations ensures safer and more effective management of PBC.
岩质骨胆脂瘤(PBC)是一种罕见的、可能危及生命的疾病,需要手术治疗以防止严重的并发症。虽然像Sanna这样的分类系统被广泛用于指导手术计划,但实际的决策往往受到病变类型以外的其他临床因素的影响。材料与方法回顾性分析1995 ~ 2024年间92例94例pbc患者的临床资料。数据包括人口统计学、临床表现、PBC分类、手术入路、内镜辅助使用、复发、随访和听力康复。本文分析了94例不同类型PBC的手术策略,评价了分类系统的实用性,并提出了一种基于内耳受累及其他关键因素的决策方法。结果最常见的PBC类型为甲髓鞘上型(40.43%),其次为大量型(18.09%)和迷路后-甲髓鞘下型(11.7%)。102例手术采用不同入路,包括改良经迷路入路(24.51%)、次全石油切除术(22.55%)和经鼻入路(18.63%)。内镜辅助治疗11例。复发率为8.51%,中位随访48.5个月。人工耳蜗植入8例,骨传导植入3例。结论spbc分类对了解病变行为和制定手术计划有重要意义,但仅凭spbc分类不足以确定最佳手术入路。决策必须个性化,考虑听力状况、内耳和面神经受累、对侧耳功能、病变扩展和解剖因素。以分类为基础的战略加上这些考虑,可确保更安全、更有效地管理PBC。
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引用次数: 0
Real-life outcomes of benralizumab treatment in chronic rhinosinusitis with nasal polyps: The BenREALizumab study benralizumab治疗慢性鼻窦炎伴鼻息肉的现实结局:BenREALizumab研究
IF 1.1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-01 DOI: 10.1016/j.otorri.2025.512291
Juan Maza-Solano , Vicente Merino-Bohórquez , Ana Gómez-Bastero , Julio Delgado-Romero , Serafín Sánchez-Gomez
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammatory disease with a significant impact on quality of life. Benralizumab has shown efficacy in severe eosinophilic asthma, but there is limited evidence for CRSwNP. A prospective observational study was conducted in a tertiary hospital with six adults with severe CRSwNP, according to EPOS2020 criteria, treated for 52 weeks. All had multiple surgeries (mean 3.3) and high cumulative exposure to systemic corticosteroids. Initially, they presented a high symptom and endoscopic burden (SNOT-22: 72; NPS: 5.2). After 16 and 52 weeks, significant improvements were observed in SNOT-22 (40.3 and 28.8), NPS (4.3 and 2.7), corticosteroid use, and complete eosinophil depletion. VAS scores improved, especially in smell, rhinorrhea, and general condition. No significant adverse events occurred. These preliminary results suggest that benralizumab may be effective in CRSwNP without associated asthma, although larger controlled studies are needed.
慢性鼻窦炎伴鼻息肉(CRSwNP)是一种显著影响生活质量的2型炎症性疾病。Benralizumab已显示出对严重嗜酸性粒细胞性哮喘的疗效,但对CRSwNP的证据有限。在一家三级医院进行了一项前瞻性观察研究,根据EPOS2020标准,6名患有严重CRSwNP的成年人接受了52周的治疗。所有患者都接受过多次手术(平均3.3次),并且全身皮质类固醇的累积暴露量很高。最初,他们表现出很高的症状和内镜负担(SNOT-22: 72; NPS: 5.2)。16周和52周后,观察到SNOT-22(40.3和28.8)、NPS(4.3和2.7)、皮质类固醇使用和完全嗜酸性粒细胞消耗的显著改善。VAS评分有所改善,尤其是在嗅觉、鼻漏和一般情况方面。无明显不良事件发生。这些初步结果表明,尽管需要更大规模的对照研究,但benralizumab可能对没有相关哮喘的CRSwNP有效。
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引用次数: 0
Efectividad del implante coclear unilateral en personas mayores de 60 años 单侧人工耳蜗在60岁以上人群中的有效性
IF 1.1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-01 DOI: 10.1016/j.otorri.2025.512285
Beatriz Tena-García , Sergio Barrientos Trigo , Francisco Ropero Romero , Serafín Sánchez-Gómez

Background and objective

Hearing loss is highly prevalent among older adults, affecting their quality of life. The aim of this study was to evaluate the audiological effectiveness of unilateral cochlear implantation (CI) in individuals over 60 years of age and to identify clinical and demographic factors influencing outcomes.

Material and methods

A single-center, longitudinal, observational, retrospective cohort study was conducted at a tertiary care hospital. Pure-tone average (PTA) thresholds and speech intelligibility (speech audiometry) were analyzed, complemented with the SSQ-12 and HISQUI-19 sound quality questionnaires. Non-parametric tests (Mann–Whitney, Kruskal–Wallis) were applied in the absence of normality, as well as Spearman's rho correlation and linear regression to examine associations between clinical and demographic variables and audiological outcomes.

Results

A cohort of 278 cochlear implant recipients aged 60 years or older was assessed. The final sample included 99 participants (71 implanted at ≥ 60 years after stratified random sampling; 28 implanted between 55–59 years). The mean implantation age was 67.7 ± 5.8 years. The mean postoperative PTA was 37,65 ± 10,71 dB, with a functional gain of 63.6 dB compared to preoperative levels. Mean speech intelligibility reached 53 ± 24,57%. Although initial associations suggested that younger implantation age and shorter duration of auditory deprivation correlated with better audiological outcomes, subsequent regression analyses did not confirm a statistically significant independent association for these variables. Non-native Spanish language use was identified as a significant negative predictor of intelligibility. Poorer thresholds were associated with family history of hearing loss (p = 0.01) and lower body mass index (p = 0.005). Among complications (8.4%), the most relevant were three CI explantation/reimplantation cases (3%).

Conclusions

Unilateral cochlear implantation is highly effective in adults over 60 years, restoring functional hearing. Overall results are comparable to younger populations, supporting the indication of cochlear implantation in older adults. Speech intelligibility showed high interindividual variability, partially explained by non-native Spanish language use. Regression analysis showed that neither implantation age nor duration of auditory deprivation had an independent association with outcomes in this cohort, and therefore should not be considered contraindications for CI. The finding that 50.5% of cases had a family history of hearing loss suggests the need to expand genetic testing in adult CI candidates. The low complication rate (8.4%) confirms the safety of cochlear implantation.
背景与目的听力损失在老年人中非常普遍,影响着他们的生活质量。本研究的目的是评估60岁以上个体单侧人工耳蜗植入(CI)的听力学效果,并确定影响结果的临床和人口统计学因素。材料与方法在某三级医院进行了一项单中心、纵向、观察性、回顾性队列研究。分析纯音平均(PTA)阈值和语音可理解度(语音测听),并辅以SSQ-12和hiski -19音质问卷。在不存在正态性的情况下应用非参数检验(Mann-Whitney, Kruskal-Wallis),以及Spearman's rho相关和线性回归来检查临床和人口统计学变量与听力学结果之间的关联。结果对278例60岁及以上的人工耳蜗受者进行了队列分析。最终样本包括99名参与者(71名分层随机抽样≥60岁植入;28名55-59岁植入)。平均着床年龄67.7±5.8岁。术后平均PTA为37,65±10,71 dB,与术前相比功能增益为63.6 dB。平均语音清晰度为53±24.57%。虽然最初的关联表明,较年轻的植入年龄和较短的听力剥夺时间与较好的听力学结果相关,但随后的回归分析并没有证实这些变量之间存在统计学上显著的独立关联。非母语西班牙语的使用被确定为可理解性的显著负向预测因子。较差的阈值与听力损失家族史(p = 0.01)和较低的体重指数(p = 0.005)相关。在并发症(8.4%)中,最相关的是3例CI外植/再植(3%)。结论单侧人工耳蜗植入术对60岁以上老年人恢复功能性听力效果显著。总体结果与年轻人群相当,支持老年人人工耳蜗植入术的适应症。语音清晰度表现出高度的个体差异,部分原因是非母语西班牙语的使用。回归分析显示,植入年龄和听觉剥夺持续时间与该队列的结果均无独立关联,因此不应视为CI的禁忌症。50.5%的病例有听力损失家族史,这一发现表明有必要扩大成年CI候选人的基因检测。低的并发症发生率(8.4%)证实了人工耳蜗植入术的安全性。
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引用次数: 0
Transoral CO2 laser microsurgery for early hypopharyngeal cancer: Still a viable option? 经口CO2激光显微手术治疗早期下咽癌:仍是可行的选择?
IF 1.1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-01 DOI: 10.1016/j.otorri.2025.512278
Carlos M. Chiesa-Estomba, Alfonso Rodriguez-Urzay, Maria Landa-Garmendia, Aitor Vargas-Alvarez, Ehkiñe Larruscain-Sarasola, Jose A. González-García, Maider Andueza-Guembe, Jon A. Sistaga-Suarez

Introduction

Hypopharyngeal squamous cell carcinoma (HPSCC) is a highly aggressive malignancy with poor prognosis due to late-stage diagnosis and complex anatomical challenges. Advances in minimally invasive techniques, particularly transoral laser microsurgery (CO2TOLMS), have demonstrated promise in improving oncologic and functional outcomes while preserving organ function.

Materials and methods

A retrospective study analyzed 25 patients with histologically confirmed HPSCC treated with CO2TOLMS at a tertiary academic hospital (2016–2021). Patients underwent curative-intent CO2TOLMS, with outcomes assessed for survival, recurrence, and functional recovery.

Results

The 3-year overall survival and disease-specific survival rates were 72% and 84%, respectively. Surgical margins were disease-free in 76% of patients, while postoperative complications were minimal (persistent tracheostomy in 4%, long-term nasogastric feeding tube dependency in 4%). Local and regional recurrence rates were each 8%. Laryngeal preservation was achieved in 95% of cases, significantly enhancing quality of life. Histologic grade correlated with recurrence risk, though survival outcomes were consistent across tumor stages and surgical margin status.

Conclusions

CO2TOLMS offers an effective and minimally invasive treatment for early-stage HPSCC, achieving good oncological and functional outcomes. While it provides low morbidity and high organ preservation rates, further research is needed to refine multimodal treatment strategies for advanced-stage disease.
下咽鳞状细胞癌(HPSCC)是一种高度侵袭性的恶性肿瘤,由于晚期诊断和复杂的解剖学挑战,预后差。微创技术的进步,特别是经口激光显微手术(CO2TOLMS),已经证明了在保持器官功能的同时改善肿瘤和功能结果的希望。材料与方法回顾性分析某三级学术医院2016-2021年25例经组织学证实的HPSCC患者接受CO2TOLMS治疗。患者接受了治疗目的CO2TOLMS,评估了生存、复发和功能恢复的结果。结果3年总生存率为72%,疾病特异性生存率为84%。76%的患者手术缘无病变,术后并发症极少(4%的患者持续气管造口,4%的患者长期鼻胃管依赖)。局部和区域复发率均为8%。95%的病例喉部得以保存,显著提高了患者的生活质量。组织学分级与复发风险相关,尽管生存结果在肿瘤分期和手术边缘状态之间是一致的。结论sco2tolms是一种有效的微创治疗早期HPSCC的方法,具有良好的肿瘤和功能预后。虽然它提供了低发病率和高器官保存率,但需要进一步研究以完善晚期疾病的多模式治疗策略。
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引用次数: 0
Eficacia y seguridad de la combinación cinarizina/dimenhidrinato frente a betahistina en el tratamiento del vértigo: revisión sistemática de la literatura cinarizin /维度水合物相对于倍他司汀治疗眩晕的有效性和安全性:系统文献综述
IF 1.1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-01 DOI: 10.1016/j.otorri.2025.512274
David Martín-Enguix , Niceto Gómez Gabaldón , Francisco J. Amaro-Gahete
Vertigo is a frequent reason for medical consultation and may result from a wide range of etiologies. Betahistine and the fixed low-dose combination of cinnarizine 20 mg and dimenhydrinate 40 mg are commonly used therapeutic options, each with distinct antivertigo profiles. This systematic review, conducted in accordance with the PRISMA guidelines, aims to compare the efficacy and safety of these two treatments in patients with vertigo of various origins. A comprehensive search was conducted in PubMed, Cochrane Library, Google Scholar, and ClinicalTrials.gov, with no restrictions on language or publication date. Eligible studies included clinical trials and meta-analyses comparing the fixed low-dose combination (20 mg/40 mg) versus betahistine (12 or 16 mg), assessing efficacy through the Mean Vertigo Score (MVS) and safety based on the incidence of adverse events (AEs). The RoB 2 and ROBIS tools were used to evaluate the risk of bias. A total of nine studies were identified (six clinical trials and three meta-analyses). In five of the six clinical trials, the fixed low-dose combination significantly reduced MVS compared with betahistine at weeks 1 and/or 4 (p < 0.05); these findings were corroborated by the three meta-analyses. Regarding safety, both treatments were well tolerated, with no serious AEs reported and a generally lower incidence observed in the fixed low-dose combination group. Overall, the fixed low-dose combination demonstrated superior clinical efficacy from the first week of treatment, along with a more favorable tolerability and safety profile. These results support its preferential use in the management of acute vestibular syndrome.
眩晕是就诊的常见原因,可能由多种病因引起。倍他司汀和固定的低剂量组合肉桂利嗪20毫克和苯海明40毫克是常用的治疗选择,每一种都有不同的抗眩晕作用。根据PRISMA指南进行的这项系统评价,旨在比较这两种治疗方法在不同来源的眩晕患者中的疗效和安全性。在PubMed、Cochrane Library、b谷歌Scholar和ClinicalTrials.gov上进行了全面的搜索,没有语言和出版日期的限制。符合条件的研究包括临床试验和荟萃分析,比较固定低剂量组合(20 mg/40 mg)与倍他司汀(12或16 mg),通过平均眩晕评分(MVS)评估疗效,以及基于不良事件发生率(ae)的安全性。使用rob2和ROBIS工具评估偏倚风险。总共确定了9项研究(6项临床试验和3项荟萃分析)。在6项临床试验中的5项中,与倍他司汀相比,固定低剂量联合治疗在第1周和/或第4周显著降低了MVS (p < 0.05);这些发现被三项荟萃分析所证实。在安全性方面,两种治疗均具有良好的耐受性,无严重不良事件报告,固定低剂量联合组的发生率普遍较低。总体而言,从治疗的第一周开始,固定低剂量组合就显示出优越的临床疗效,同时具有更有利的耐受性和安全性。这些结果支持其优先用于治疗急性前庭综合征。
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引用次数: 0
Newborn nasal obstruction: Rare anatomical causes to consider 新生儿鼻塞:罕见解剖原因考虑
IF 1.1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-01 DOI: 10.1016/j.otorri.2025.512279
Montserrat Asensi-Diaz , Alejandro Lowy Benoliel , Juan Antonio Pasamontes Pingarron , Ismael Nieva Pascual , Pilar Cifuentes Canorea , Monica Hernando Cuñado
Neonatal nasal obstruction, though rare, can be life-threatening due to the obligate nasal breathing pattern in newborns. Even partial obstruction may compromise ventilation and feeding.
This study aims to describe rare anatomical causes of neonatal nasal obstruction, highlighting their clinical presentation, diagnostic evaluation, and management.
A retrospective review was conducted of four neonates with respiratory distress who were diagnosed with congenital nasal malformations through endoscopic examination and craniofacial imaging. The identified cases included bilateral choanal atresia in a patient with CHARGE syndrome, congenital nasal pyriform aperture stenosis (CNPAS) with a solitary median mega-incisor, isolated CNPAS with midnasal hypoplasia, and bilateral congenital dacryocystoceles. Symptoms ranged from noisy breathing to feeding intolerance. Management included both medical and surgical interventions depending on the severity of the obstruction.
Although infrequent, anatomical nasal anomalies should be promptly considered in neonates presenting with respiratory distress, as early diagnosis and appropriate treatment are essential to avoid complications and ensure favourable outcomes.
新生儿鼻塞虽然罕见,但由于新生儿专性鼻呼吸模式,可能危及生命。即使部分梗阻也可能影响通气和进食。本研究旨在描述罕见的新生儿鼻塞解剖原因,强调其临床表现,诊断评估和处理。本文对4例经鼻内镜检查及颅面影像学诊断为先天性鼻畸形的呼吸窘迫新生儿进行回顾性分析。确定的病例包括双侧后肛门闭锁患者CHARGE综合征,先天性梨形鼻孔狭窄(CNPAS)伴孤立中切牙,孤立性CNPAS伴中鼻发育不全,以及双侧先天性泪囊膨出。症状从嘈杂的呼吸到进食不耐受。根据梗阻的严重程度,治疗包括内科和外科干预。虽然不常见,但在出现呼吸窘迫的新生儿中应及时考虑解剖性鼻异常,因为早期诊断和适当治疗对于避免并发症和确保良好的结果至关重要。
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引用次数: 0
Validación del cuestionario de autoevaluación para pacientes con parálisis vocal unilateral (PVU-HI-10) en castellano 西班牙文单侧声瘫患者自我评估问卷(PVU-HI-10)的验证
IF 1.1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-01 DOI: 10.1016/j.otorri.2025.512271
Rosa Hernández-Sandemetrio , Natsuki Oishi , Isabel López , Cristina Rodríguez-Prado , Isabel García-Lopez , Enrique Zapater

Introduction and objective

Unilateral vocal cord paralysis (UVCP) is a condition that directly affects laryngeal functions. While most cases have an organic cause, idiopathic cases have also been described. Patients with UVCP often experience symptoms that impact not only their vocal abilities but also their nutritional and social well-being. Our primary objective is to validate a self-assessment questionnaire for patients with UVCP and unilateral vocal immobility, incorporating questions that cover all possible symptoms of this condition, adapted to the Spanish spoken in Spain.

Methodology

This is a prospective observational study using the PVU-HI-10 questionnaire, which assesses the functional, physical, and emotional impact of UVCP-related symptoms. For validation, we statistically evaluated test-retest reliability, item-total correlation, internal consistency, concurrent validity, and discriminative validity, with sensitivity and specificity analysis. A total of 62 subjects participated: 33 patients (case group) and 29 healthy individuals (control group). All participants completed the PVU-HI-10 questionnaire twice, with a three-week interval between assessments and no treatment administered between them. The maximum phonation time (MPT) was used as the objective reference measure.

Results

The test-retest reliability was high, with an intraclass correlation coefficient (ICC) of 0.95. Internal consistency, measured using McDonald's omega coefficient, was 0.91 for the case group and 0.94 for the control group. The correlation between MPT and questionnaire scores was strong and inversely related (-0.61 and -0.67, respectively). Discriminative validity was demonstrated using the ROC curve, with a cutoff point of 12.1, yielding a sensitivity of 82% and a specificity of 93.1%.

Conclusions

In the management of unilateral vocal immobility, it is essential to consider the degree of disability caused by the symptoms. The PVU-HI-10 is a condition-specific questionnaire that has shown high reliability and validity. It is a brief, simple test that provides a numerical result, allowing for the quantification and comparison of treatment outcomes. This makes it a useful tool in the evaluation protocol for patients with unilateral vocal paralysis in Spanish-speaking populations.
单侧声带麻痹(UVCP)是一种直接影响喉功能的疾病。虽然大多数病例有器质性原因,但也有特发性病例。UVCP患者经常经历的症状不仅影响他们的发声能力,还影响他们的营养和社会福利。我们的主要目的是验证UVCP和单侧声音不动患者的自我评估问卷,包括涵盖该疾病所有可能症状的问题,适用于西班牙语。方法:这是一项前瞻性观察性研究,使用PVU-HI-10问卷,评估uvcp相关症状对功能、身体和情绪的影响。为了验证,我们统计评估了测试-重测信度、项目-总相关性、内部一致性、并发效度和判别效度,并进行了敏感性和特异性分析。共62例受试者参与:患者33例(病例组),健康个体29例(对照组)。所有参与者完成PVU-HI-10问卷两次,评估间隔三周,两次之间不进行任何治疗。以最大发声时间(MPT)作为客观参考指标。结果重测信度高,类内相关系数(ICC)为0.95。内部一致性,用麦当劳的ω系数测量,病例组为0.91,对照组为0.94。MPT与问卷得分呈显著负相关(分别为-0.61和-0.67)。使用ROC曲线证明了判别效度,截止点为12.1,灵敏度为82%,特异性为93.1%。结论在单侧声带不动症的治疗中,应考虑症状引起的残疾程度。PVU-HI-10是一份具有较高信度和效度的专项问卷。这是一个简短、简单的测试,提供一个数值结果,允许对治疗结果进行量化和比较。这使得它成为西班牙语人群中单侧声带麻痹患者评估方案的有用工具。
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引用次数: 0
Resultados de las versiones españolas del Cuestionario de otitis media crónica-12 (COMQ-12) y del Inventario de beneficios de otitis media crónica (COMBI) en pacientes y controles en nuestro medio 中耳炎-12调查问卷(COMQ-12)和中耳炎-慢性中耳炎益处清单(COMBI)西班牙文版在我们地区的患者和对照组的结果
IF 1.1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-01 DOI: 10.1016/j.otorri.2025.512273
Alberto Codina , Berta Alegre , Elena Hernández-Montero , Jorge Vega , Miguel Caballero-Borrego , Francisco Larrosa

Background and objective

The Chronic Otitis Media Questionnaire-12 (COMQ-12) and the Chronic Otitis Media Benefits Inventory (COMBI) seek to assess the quality of life related to chronic otitis media or its surgical treatment. The objective of this study was to determine and evaluate the scores of the Spanish versions of the COMQ-12 and the COMBI.

Materials and methods

Multicenter retrospective study. Mean scores of the Spanish versions (COMQ-12-Spa and COMBI-Spa) were compared in consecutive adult patients diagnosed with chronic otitis media (COM), with or without cholesteatoma, undergoing tympanoplasty with and/or mastoidectomy and in a separate cohort of unaffected adults.

Results

120 patients and 60 unnaffected adults completed the study. The mean score of the COMQ-12-Spa in patients with COM and in healthy adults was 22.95 ± 11.72 and 0.8 ± 1.3 respectively (p < 0.0001). COMQ-12-Spa did not discriminate between COM without (21.9 ± 10.45) and with cholesteatoma (23.82 ± 9.53) (P > 0.05). COMBI-Spa showed a mean postoperative score of 46.02 ± 9.08 and was not able to discriminate between tympanoplasty without mastoidectomy (48.01 ± 8.09) and mastoidectomy (45.32 ± 10.03) (P > 0.05).

Conclusions

The COMQ-12-Spa and the COMBI-Spa allow the pre- and post-intervention evaluation of the subjective severity of COM in adult patients in our setting, so their use is recommended.
背景与目的慢性中耳炎问卷-12 (COMQ-12)和慢性中耳炎获益量表(COMBI)旨在评估与慢性中耳炎或其手术治疗相关的生活质量。本研究的目的是确定和评估西班牙语版COMQ-12和COMBI的分数。材料与方法多中心回顾性研究。西班牙版本(COMQ-12-Spa和COMBI-Spa)的平均得分在连续诊断为慢性中耳炎(COM)的成人患者中进行比较,伴有或不伴有胆脂瘤,接受鼓室成形术和/或乳突切除术,并在未受影响的成人单独队列中进行比较。结果120名患者和60名未受影响的成年人完成了研究。COMQ-12-Spa在COM患者和健康成人中的平均得分分别为22.95±11.72和0.8±1.3 (p < 0.0001)。COMQ-12-Spa对无胆脂瘤的COM(21.9±10.45)和合并胆脂瘤的COM(23.82±9.53)无显著性差异(P > 0.05)。COMBI-Spa评分平均为46.02±9.08分,无法区分鼓室成形术+乳突切除术(48.01±8.09)和乳突切除术(45.32±10.03)(P > 0.05)。结论COMQ-12-Spa和COMBI-Spa可以在干预前和干预后评估成人COM患者的主观严重程度,因此推荐使用。
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引用次数: 0
Speech discrimination and binaural processing in bilateral symmetric vs. asymmetric sensorineural hearing loss 双侧对称型与非对称型感音神经性听力损失的言语辨别与双耳加工
IF 1.1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-09-01 DOI: 10.1016/j.otorri.2025.512265
Mai El Ghazaly, Esraa Meckawy, Hesham Kozou, Doaa Elmoazen

Purpose

To investigate the effects of symmetric and asymmetric sensorineural hearing loss (SSNHL and ASNHL) on speech discrimination abilities and binaural processing, including integration and interaction.

Materials and methods

This cross-sectional study included 36 adult patients with bilateral sensorineural hearing loss, divided into two groups based on the symmetry of their hearing loss: ASNHL and SSNHL. Speech discrimination abilities were evaluated using the maximum speech discrimination score (SDSmax) with Arabic monosyllabic words. Binaural integration was assessed using the free-recall double dichotic digit test (DDT), while binaural interaction was evaluated through the binaural fusion test (BFT).

Results

The SDSmax of the worse-hearing ear in ASNHL patients (48.89 ± 10.13%) was significantly lower than in SSNHL patients (69.33 ± 7.97%) with comparable degrees of hearing loss. ASNHL patients exhibited a greater disparity between the better and worse-hearing ears in DDT scores (53.15 ± 13.98%) compared to SSNHL patients (22.96 ± 5.93%). Additionally, the BFT scores in ASNHL patients (55.14 ± 13.30%) were significantly lower than in SSNHL patients (72.92 ± 12.55%).

Conclusions

ASNHL patients experience greater impairments in speech discrimination, binaural integration, and interaction compared to SSNHL patients. These differences likely stem from auditory deprivation and asymmetry-induced deficits. Developing tailored hearing rehabilitation strategies is critical to addressing the unique challenges posed by asymmetric hearing loss.
目的探讨对称型和非对称型感音神经性听力损失(SSNHL和ASNHL)对言语辨别能力和双耳加工(包括整合和交互)的影响。材料与方法横断面研究36例成年双侧感音神经性听力损失患者,根据听力损失的对称性分为ASNHL组和SSNHL组。用阿拉伯语单音节词的最大言语辨别分数(SDSmax)评价言语辨别能力。采用自由回忆双双指测试(DDT)评估双耳整合,通过双耳融合测试(BFT)评估双耳相互作用。结果听力损失程度相当的ASNHL患者听力差耳SDSmax(48.89±10.13%)明显低于听力损失程度相当的SSNHL患者(69.33±7.97%)。ASNHL患者的滴滴涕评分(53.15±13.98%)比SSNHL患者(22.96±5.93%)差异更大。ASNHL患者BFT评分(55.14±13.30%)明显低于SSNHL患者(72.92±12.55%)。结论与SSNHL患者相比,SSNHL患者在言语识别、双耳整合和互动方面存在更大的障碍。这些差异可能源于听觉剥夺和不对称引起的缺陷。制定量身定制的听力康复策略对于解决不对称听力损失带来的独特挑战至关重要。
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引用次数: 0
Aberrant intratympanic internal carotid artery 腔内颈内动脉异常
IF 1.1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-09-01 DOI: 10.1016/j.otorri.2025.512268
Saúl Astray-Gómez , Celia Montón-Gómez , Carlos de Paula-Vernetta
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引用次数: 0
期刊
Acta otorrinolaringologica espanola
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