首页 > 最新文献

Acta otorrinolaringologica espanola最新文献

英文 中文
Variantes de afectación del conducto semicircular posterior en el vértigo posicional paroxístico benigno 良性阵发性位置性眩晕后半规管受累的变异情况
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.otorri.2024.01.009

Benign paroxysmal positional vertigo is the most common cause of peripheral vertigo. It is characterized by short and recurrent episodes of vertigo, trigged by specific head movements that displace otoconia within the semicircular canals. The movement of dislodge otoconia from the utricle cause abnormal positional endolymphatic currents. Primary treatment involves reposition maneuvers aimed at moving the displaced otoconia out the affected canal, therefore correct identification of the affected canal is essential for the diagnosis. The posterior semicircular canal (PSC) is the most frequently affected due to its spatial orientation and the force of gravity. Recent technological advances have allowed for better assessment of positional nystagmus during diagnostic and therapeutic maneuvers, revealing various possible scenarios of PSC involvement. Regarding the PSC, otoconia may be found in different parts of the canal, and not just in the expected location, floating in the long arm of the canal. The understanding of these variants is crucial, as the prognosis and the disease progression differ in such cases. This review aims to describe the six possible variants of PSC involvement described so far.

良性阵发性位置性眩晕是周围性眩晕最常见的病因。它的特点是眩晕发作时间短且反复发作,由特定的头部运动引发,使耳膜在半规管内移位。耳膜从耳道移位的运动会导致位置异常的内淋巴电流。初级治疗包括重新定位操作,目的是将移位的耳膜移出受影响的耳道,因此正确识别受影响的耳道对诊断至关重要。由于后半规管(PSC)的空间方向和重力作用,它最常受到影响。最近的技术进步使得在诊断和治疗过程中可以更好地评估位置性眼球震颤,从而揭示出 PSC 受影响的各种可能情况。关于 PSC,耳骨膜可能出现在耳道的不同部位,而不仅仅是在预期的位置,如耳道长臂的浮动。了解这些变异是至关重要的,因为在这些病例中,预后和疾病的进展都不尽相同。本综述旨在描述迄今所描述的 PSC 受累的六种可能变异。
{"title":"Variantes de afectación del conducto semicircular posterior en el vértigo posicional paroxístico benigno","authors":"","doi":"10.1016/j.otorri.2024.01.009","DOIUrl":"10.1016/j.otorri.2024.01.009","url":null,"abstract":"<div><p>Benign paroxysmal positional vertigo is the most common cause of peripheral vertigo. It is characterized by short and recurrent episodes of vertigo, trigged by specific head movements that displace otoconia within the semicircular canals. The movement of dislodge otoconia from the utricle cause abnormal positional endolymphatic currents. Primary treatment involves reposition maneuvers aimed at moving the displaced otoconia out the affected canal, therefore correct identification of the affected canal is essential for the diagnosis. The posterior semicircular canal (PSC) is the most frequently affected due to its spatial orientation and the force of gravity. Recent technological advances have allowed for better assessment of positional nystagmus during diagnostic and therapeutic maneuvers, revealing various possible scenarios of PSC involvement. Regarding the PSC, otoconia may be found in different parts of the canal, and not just in the expected location, floating in the long arm of the canal. The understanding of these variants is crucial, as the prognosis and the disease progression differ in such cases. This review aims to describe the six possible variants of PSC involvement described so far.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 5","pages":"Pages 324-334"},"PeriodicalIF":0.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140085681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumor fibromixoide osificante en región supraclavicular 锁骨上区域纤维肌骨化性肿瘤
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.otorri.2024.02.001
{"title":"Tumor fibromixoide osificante en región supraclavicular","authors":"","doi":"10.1016/j.otorri.2024.02.001","DOIUrl":"10.1016/j.otorri.2024.02.001","url":null,"abstract":"","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 5","pages":"Pages 338-339"},"PeriodicalIF":0.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140086390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perfil clínico, resultados otológicos y auditivos en niños con síndrome de Down 唐氏综合症儿童的临床特征、耳科和听力结果
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.otorri.2024.03.003
Joan Lorente-Piera, Raquel Manrique-Huarte, Manuel Manrique, Francisco Javier Cervera-Paz

Introduction and objectives

Even though the incidence has decreased in recent years, Down syndrome remains the most common chromosomal disorder today. Despite being a condition with multisystemic involvement, it often tends to affect the head and neck area, making it a frequent reason for consultation with pediatric otolaryngologists or otologists. The purpose of this work is to be one of the first in Spain to characterize and describe the pathology and therapeutic approach typically provided to these patients, analyzing the evolution from a clinical and auditory perspective.

Material and methods

We aim to analyze a sample of 16 pediatric patients recruited over the past 24 years, diagnosed with Down syndrome, and experiencing a wide range of diseases affecting the ear and its auditory function.

Results

62.50% of the patients were women, whose main reason for seeking specialist care was acute and serous otitis media, accounting for 31.25%. These patients have an indication for treatment for various entities within the otological sphere that usually do not differ from those of a healthy child. However, the evolution and response to treatments can take on a torpid character due to the anatomical characteristics of the ears of these patients.

Conclusions

Although the frequency of children with Down syndrome in the pediatric otolaryngologist's clinic is decreasing, these patients have a predisposition to ear diseases with auditory repercussions, with variable evolution depending on the disease and the child's intrinsic characteristics.

简介和目的尽管近年来唐氏综合征的发病率有所下降,但它仍然是当今最常见的染色体疾病。尽管唐氏综合征是一种涉及多系统的疾病,但它往往会影响头颈部,这也是儿科耳鼻喉科医生或耳科医生经常会诊的原因。这项工作的目的是在西班牙率先描述和描述这些患者的病理特征和典型的治疗方法,并从临床和听觉角度分析其演变过程。材料和方法我们的目标是分析过去 24 年中招募的 16 名儿科患者样本,这些患者被诊断患有唐氏综合征,并经历了影响耳朵及其听觉功能的多种疾病。这些患者有治疗耳科领域各种疾病的指征,通常与健康儿童没有区别。结论虽然唐氏综合征患儿在小儿耳鼻喉科门诊中的就诊率正在下降,但这些患儿易患对听觉有影响的耳部疾病,其病情变化取决于疾病和患儿的内在特征。
{"title":"Perfil clínico, resultados otológicos y auditivos en niños con síndrome de Down","authors":"Joan Lorente-Piera,&nbsp;Raquel Manrique-Huarte,&nbsp;Manuel Manrique,&nbsp;Francisco Javier Cervera-Paz","doi":"10.1016/j.otorri.2024.03.003","DOIUrl":"10.1016/j.otorri.2024.03.003","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Even though the incidence has decreased in recent years, Down syndrome remains the most common chromosomal disorder today. Despite being a condition with multisystemic involvement, it often tends to affect the head and neck area, making it a frequent reason for consultation with pediatric otolaryngologists or otologists. The purpose of this work is to be one of the first in Spain to characterize and describe the pathology and therapeutic approach typically provided to these patients, analyzing the evolution from a clinical and auditory perspective.</p></div><div><h3>Material and methods</h3><p>We aim to analyze a sample of 16 pediatric patients recruited over the past 24 years, diagnosed with Down syndrome, and experiencing a wide range of diseases affecting the ear and its auditory function.</p></div><div><h3>Results</h3><p>62.50% of the patients were women, whose main reason for seeking specialist care was acute and serous otitis media, accounting for 31.25%. These patients have an indication for treatment for various entities within the otological sphere that usually do not differ from those of a healthy child. However, the evolution and response to treatments can take on a torpid character due to the anatomical characteristics of the ears of these patients.</p></div><div><h3>Conclusions</h3><p>Although the frequency of children with Down syndrome in the pediatric otolaryngologist's clinic is decreasing, these patients have a predisposition to ear diseases with auditory repercussions, with variable evolution depending on the disease and the child's intrinsic characteristics.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 5","pages":"Pages 296-303"},"PeriodicalIF":0.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142233591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Upper airway manifestations of anti-IgLON5 disease: Otorhinolaryngological point of view 抗IgLON5疾病的上呼吸道表现:耳鼻喉科观点
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.otorri.2024.04.001
Daniela Pastene , Eduardo Lehrer , Sara Jubes , Joan Santamaria , Alex Iranzo , Carles Gaig , Isabel Vilaseca

Introduction

Anti-IgLON5 disease is a recently described neurological disorder with multisystemic features. The disease is characterized by the presence of IgLON5 antibodies in serum and cerebrospinal fluid. Our objective is to describe in detail the otorhinolaryngological manifestations of this disease, which are frequent and may include dysphagia, dysarthria, vocal cord paralysis and laryngospasm.

Methods

In this study, we present a series of 9 patients with anti-IgLON5 disease and otolaryngological manifestations. Patients were evaluated between July 2012 and March 2022 by video-polysomnography, fiber-optic laryngoscopy, and functional endoscopic evaluation of swallowing.

Results

The median age was 71 years, and 5 (56%) were female. Video-polysomnography showed a NREM/REM parasomnia in 6 patients (67%), obstructive sleep apnea in 8 (88%), stridor during sleep in 7 (78%) and central apneas in 1 (11%). Six out of the 9 patients (67%) presented episodes of acute respiratory failure that required mechanical ventilation, 6 had vocal fold palsy with 4 of them requiring tracheostomy (3 had to be performed on an emergency basis). Dysphagia occurred in 8 patients (89%). Prominent upper airway secretion and sialorrhea was also present in 3 cases.

Conclusion

The anti-IgLON5 disease exhibits extensive otolaryngological symptoms, mainly affecting the upper airway. These symptoms affect the quality of life and can be life-threatening. Prompt acute management is essential for stridor, dyspnea, and dysphagia. Given the potential severity of the symptoms and rarity of the disease, it is important for otolaryngologists to be familiar with anti-IgLON5 disease.

Level of evidence

Level 4.

导言抗 IgLON5 病是最近描述的一种具有多系统特征的神经系统疾病。该病的特征是血清和脑脊液中存在 IgLON5 抗体。我们的目的是详细描述该病的耳鼻喉科表现,这些表现很常见,可能包括吞咽困难、构音障碍、声带麻痹和喉痉挛。2012年7月至2022年3月期间,我们通过视频多导睡眠图、纤维喉镜和吞咽功能内窥镜对患者进行了评估。视频多导睡眠图显示,6 名患者(67%)患有 NREM/REM寄生虫性失眠,8 名患者(88%)患有阻塞性睡眠呼吸暂停,7 名患者(78%)在睡眠中出现呼吸困难,1 名患者(11%)出现中枢性呼吸暂停。9 名患者中有 6 人(67%)出现急性呼吸衰竭,需要进行机械通气,6 人出现声带麻痹,其中 4 人需要进行气管造口术(3 人必须紧急进行)。8名患者(89%)出现吞咽困难。结论抗 IgLON5 疾病表现出广泛的耳鼻喉症状,主要影响上呼吸道。这些症状会影响患者的生活质量,甚至危及生命。对于喘鸣、呼吸困难和吞咽困难,及时的急性处理至关重要。鉴于症状的潜在严重性和疾病的罕见性,耳鼻喉科医生必须熟悉抗IgLON5疾病。
{"title":"Upper airway manifestations of anti-IgLON5 disease: Otorhinolaryngological point of view","authors":"Daniela Pastene ,&nbsp;Eduardo Lehrer ,&nbsp;Sara Jubes ,&nbsp;Joan Santamaria ,&nbsp;Alex Iranzo ,&nbsp;Carles Gaig ,&nbsp;Isabel Vilaseca","doi":"10.1016/j.otorri.2024.04.001","DOIUrl":"10.1016/j.otorri.2024.04.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Anti-IgLON5 disease is a recently described neurological disorder with multisystemic features. The disease is characterized by the presence of IgLON5 antibodies in serum and cerebrospinal fluid. Our objective is to describe in detail the otorhinolaryngological manifestations of this disease, which are frequent and may include dysphagia, dysarthria, vocal cord paralysis and laryngospasm.</p></div><div><h3>Methods</h3><p>In this study, we present a series of 9 patients with anti-IgLON5 disease and otolaryngological manifestations. Patients were evaluated between July 2012 and March 2022 by video-polysomnography, fiber-optic laryngoscopy, and functional endoscopic evaluation of swallowing.</p></div><div><h3>Results</h3><p>The median age was 71 years, and 5 (56%) were female. Video-polysomnography showed a NREM/REM parasomnia in 6 patients (67%), obstructive sleep apnea in 8 (88%), stridor during sleep in 7 (78%) and central apneas in 1 (11%). Six out of the 9 patients (67%) presented episodes of acute respiratory failure that required mechanical ventilation, 6 had vocal fold palsy with 4 of them requiring tracheostomy (3 had to be performed on an emergency basis). Dysphagia occurred in 8 patients (89%). Prominent upper airway secretion and sialorrhea was also present in 3 cases.</p></div><div><h3>Conclusion</h3><p>The anti-IgLON5 disease exhibits extensive otolaryngological symptoms, mainly affecting the upper airway. These symptoms affect the quality of life and can be life-threatening. Prompt acute management is essential for stridor, dyspnea, and dysphagia. Given the potential severity of the symptoms and rarity of the disease, it is important for otolaryngologists to be familiar with anti-IgLON5 disease.</p></div><div><h3>Level of evidence</h3><p>Level 4.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 5","pages":"Pages 288-295"},"PeriodicalIF":0.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142233628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Actualización y validación del test percepción temprana de la palabra en lengua española 更新和验证西班牙语早期词语感知测试
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.otorri.2023.11.002

Introduction

It is extremely important to assess speech perception skills in children with hearing loss, since these skills are essential to guide the rehabilitation process.

Objective

Update and validate the Early Speech Perception test in Spanish in normal-hearing children.

Method

Different drawings were selected from children's books used daily in the work of teachers and speech therapists. 69 children aged between 3 and 8 years old participated in the study, divided into 6 groups by age (group 1, 3 years of age [n = 13]; group 2, 4 years of age [n = 15]; group 3, 5 years of age [n = 12]; group 4, 6 years of age [n = 8]; group 5, 7 years of age [n = 10]; group 6, 8 years of age [n = 11]). For each category of the test, the children had to name and point to the corresponding drawing.

Results

The difference between age and gender groups was statistically evaluated. For the naming phase, a significant difference was observed between groups 1 and group 5; and between group 1 and group 6. For the pointing phase there was no difference between the groups, and in all groups, there was a score greater than 98%. In relation to gender, there was no difference between the groups.

Conclusion

The present study demonstrates that the material developed to assess auditory reception in normal-hearing children from 3 to 8 years old is appropriate.

导言:评估听力损失儿童的言语感知能力极为重要,因为这些能力对指导康复过程至关重要。方法从教师和言语治疗师日常使用的儿童读物中选取不同的图画。69 名 3 至 8 岁的儿童参加了研究,按年龄分为 6 组(第 1 组,3 岁[n=13];第 2 组,4 岁[n=15];第 3 组,5 岁[n=12];第 4 组,6 岁[n=8];第 5 组,7 岁[n=10];第 6 组,8 岁[n=11])。在每个测试类别中,儿童都必须说出相应图画的名称并指出该图画。在命名阶段,第 1 组和第 5 组之间以及第 1 组和第 6 组之间存在显著差异。 在指画阶段,各组之间没有差异,所有组别的得分率都高于 98%。本研究表明,为评估 3 至 8 岁听力正常儿童的听觉接收能力而开发的材料是合适的。
{"title":"Actualización y validación del test percepción temprana de la palabra en lengua española","authors":"","doi":"10.1016/j.otorri.2023.11.002","DOIUrl":"10.1016/j.otorri.2023.11.002","url":null,"abstract":"<div><h3>Introduction</h3><p>It is extremely important to assess speech perception skills in children with hearing loss, since these skills are essential to guide the rehabilitation process.</p></div><div><h3>Objective</h3><p>Update and validate the Early Speech Perception test in Spanish in normal-hearing children.</p></div><div><h3>Method</h3><p>Different drawings were selected from children's books used daily in the work of teachers and speech therapists. 69 children aged between 3 and 8 years old participated in the study, divided into 6 groups by age (group 1, 3 years of age [n<!--> <!-->=<!--> <!-->13]; group 2, 4 years of age [n<!--> <!-->=<!--> <!-->15]; group 3, 5 years of age [n<!--> <!-->=<!--> <!-->12]; group 4, 6 years of age [n<!--> <!-->=<!--> <!-->8]; group 5, 7 years of age [n<!--> <!-->=<!--> <!-->10]; group 6, 8 years of age [n<!--> <!-->=<!--> <!-->11]). For each category of the test, the children had to name and point to the corresponding drawing.</p></div><div><h3>Results</h3><p>The difference between age and gender groups was statistically evaluated. For the naming phase, a significant difference was observed between groups 1 and group 5; and between group 1 and group 6. For the pointing phase there was no difference between the groups, and in all groups, there was a score greater than 98%. In relation to gender, there was no difference between the groups.</p></div><div><h3>Conclusion</h3><p>The present study demonstrates that the material developed to assess auditory reception in normal-hearing children from 3 to 8 years old is appropriate.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 5","pages":"Pages 281-287"},"PeriodicalIF":0.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140277942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Proliferating Cell Nuclear Antigen (PCNA) Expression among Nasal Polyp and Chronic Rhinosinusitis 鼻息肉和慢性鼻窦炎中增殖细胞核抗原 (PCNA) 表达的比较
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.otorri.2024.02.002
Alireza Barouh M.D. , Mohammadreza Jalali Nadoushan M.D. , Masood Soltanipur M.D.

Background and objective

Chronic rhinosinusitis is a common inflammatory disorder in sinonasal mucosa that could be developed with or without nasal polyps. Cellular proliferation is suggested as a possible mechanism of nasal polyp development. However, conducted studies in this context are limited. So, the present study's aim is the comparison of proliferating cell nuclear antigen (PCNA) expression in nasal polyps and chronic rhinosinusitis.

Materials and methods

In this cross-sectional study, 70 nasal polyp and 60 chronic rhinosinusitis samples from patients referred to Mostafa Khomeini Hospital, Tehran from 2017 to 2022 were immunohistochemically stained by PCNA marker. The percentage of PCNA nuclear expression was determined in two groups and its association with the type of pathological lesion and the patient's age and sex was analyzed by SPSS statistic software version 24 statistical software (IBM Statistics, USA).

Results

The mean percentage expression of PCNA in nasal polyp and chronic rhinosinusitis samples was 16.55 ± 13.66 and 17.58 ± 12.68 respectively (ranging from 0 to 57 in both groups) however, there was no significant statistical difference between the two groups (p = 0.479). No relationship was found between PCNA expression with age and sex in none of the chronic rhinosinusitis and nasal polyp groups.

Conclusion

Proliferative activity of the nasal epithelial cell is similar in chronic rhinosinusitis with and without nasal polyps and it is considered that the increase of epithelial cell proliferative activity probably has no role in nasal polyp development in patients with chronic rhinosinusitis.

背景和目的 慢性鼻炎是鼻窦粘膜常见的炎症性疾病,可伴有或不伴有鼻息肉。细胞增殖被认为是鼻息肉发生的可能机制。然而,这方面的研究还很有限。因此,本研究的目的是比较鼻息肉和慢性鼻窦炎中增殖细胞核抗原(PCNA)的表达情况。材料和方法在这项横断面研究中,对 2017 年至 2022 年期间转诊至德黑兰 Mostafa Khomeini 医院的 70 例鼻息肉和 60 例慢性鼻窦炎患者样本进行了 PCNA 标记免疫组化染色。结果鼻息肉和慢性鼻窦炎样本中 PCNA 的平均表达百分比分别为 16.55 ± 13.66 和 17.58 ± 12.68(两组均为 0 至 57),但两组间无显著统计学差异(P = 0.479)。结论有鼻息肉和无鼻息肉的慢性鼻炎患者鼻腔上皮细胞的增殖活性相似,因此认为上皮细胞增殖活性的增加可能与慢性鼻炎患者鼻息肉的发生无关。
{"title":"Comparison of Proliferating Cell Nuclear Antigen (PCNA) Expression among Nasal Polyp and Chronic Rhinosinusitis","authors":"Alireza Barouh M.D. ,&nbsp;Mohammadreza Jalali Nadoushan M.D. ,&nbsp;Masood Soltanipur M.D.","doi":"10.1016/j.otorri.2024.02.002","DOIUrl":"10.1016/j.otorri.2024.02.002","url":null,"abstract":"<div><h3>Background and objective</h3><p>Chronic rhinosinusitis is a common inflammatory disorder in sinonasal mucosa that could be developed with or without nasal polyps. Cellular proliferation is suggested as a possible mechanism of nasal polyp development. However, conducted studies in this context are limited. So, the present study's aim is the comparison of proliferating cell nuclear antigen (PCNA) expression in nasal polyps and chronic rhinosinusitis.</p></div><div><h3>Materials and methods</h3><p>In this cross-sectional study, 70 nasal polyp and 60 chronic rhinosinusitis samples from patients referred to Mostafa Khomeini Hospital, Tehran from 2017 to 2022 were immunohistochemically stained by PCNA marker. The percentage of PCNA nuclear expression was determined in two groups and its association with the type of pathological lesion and the patient's age and sex was analyzed by SPSS statistic software version 24 statistical software (IBM Statistics, USA).</p></div><div><h3>Results</h3><p>The mean percentage expression of PCNA in nasal polyp and chronic rhinosinusitis samples was 16.55 ± 13.66 and 17.58 ± 12.68 respectively (ranging from 0 to 57 in both groups) however, there was no significant statistical difference between the two groups (p = 0.479). No relationship was found between PCNA expression with age and sex in none of the chronic rhinosinusitis and nasal polyp groups.</p></div><div><h3>Conclusion</h3><p>Proliferative activity of the nasal epithelial cell is similar in chronic rhinosinusitis with and without nasal polyps and it is considered that the increase of epithelial cell proliferative activity probably has no role in nasal polyp development in patients with chronic rhinosinusitis.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 5","pages":"Pages 310-315"},"PeriodicalIF":0.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142233593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bone cement in ossicular chain reconstruction: systematic review and meta-analysis 骨水泥在骨链重建中的应用:系统回顾与荟萃分析
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.otorri.2024.01.003
Luís Roque Reis , Kaamil Gani , André Sá Pereira , Pedro Branco , Pedro Escada

Objectives

To compare the hearing outcomes of ossicular chain reconstruction using bone cement versus other materials such as prostheses and autografts.

Methods

This study included articles that compared hearing outcomes in patients with conductive hearing loss who underwent stapes revision surgery or chronic otitis media surgery. A systematic search for articles from January 2000 to February 2022 was conducted in Medline, Embase, and Cochrane Library databases. Only articles in English were included. An effective postoperative air-bone gap (ABG) was defined as ≤20 dB. A bias assessment tool was developed according to Cochrane guidelines, and the chi-square test was used to evaluate the mean age of the samples.

Results

Of the 418 studies that met the selection criteria, only seven were eligible for this study, consisting of 187 patients in the bone cement group and 173 in the non-bone cement group. Ossiculoplasty using bone cement yielded significantly better results, with a combined odds ratio (OR) of 2.03 (95% CI: 1.16–3.55, p = 0.01).

Conclusions

The results of this study suggest that the effectiveness of bone cement in ossiculoplasty was greater than that of other materials in chronic otitis media surgery or stapes revision surgery, with a higher number of patients achieving ABG ≤20 dB.

方法本研究纳入了对接受镫骨翻修手术或慢性中耳炎手术的传导性听力损失患者的听力结果进行比较的文章。研究人员在 Medline、Embase 和 Cochrane Library 数据库中对 2000 年 1 月至 2022 年 2 月期间的文章进行了系统检索。仅纳入英文文章。术后有效气骨间隙(ABG)定义为≤20 dB。结果 在符合筛选标准的418篇研究中,只有7篇符合本研究的条件,其中骨水泥组187名患者,非骨水泥组173名患者。结论本研究结果表明,在慢性中耳炎手术或镫骨翻修手术中,骨水泥在听骨成形术中的效果优于其他材料,有更多患者的ABG达到≤20 dB。
{"title":"Bone cement in ossicular chain reconstruction: systematic review and meta-analysis","authors":"Luís Roque Reis ,&nbsp;Kaamil Gani ,&nbsp;André Sá Pereira ,&nbsp;Pedro Branco ,&nbsp;Pedro Escada","doi":"10.1016/j.otorri.2024.01.003","DOIUrl":"10.1016/j.otorri.2024.01.003","url":null,"abstract":"<div><h3>Objectives</h3><p>To compare the hearing outcomes of ossicular chain reconstruction using bone cement versus other materials such as prostheses and autografts.</p></div><div><h3>Methods</h3><p>This study included articles that compared hearing outcomes in patients with conductive hearing loss who underwent stapes revision surgery or chronic otitis media surgery. A systematic search for articles from January 2000 to February 2022 was conducted in Medline, Embase, and Cochrane Library databases. Only articles in English were included. An effective postoperative air-bone gap (ABG) was defined as ≤20 dB. A bias assessment tool was developed according to Cochrane guidelines, and the chi-square test was used to evaluate the mean age of the samples.</p></div><div><h3>Results</h3><p>Of the 418 studies that met the selection criteria, only seven were eligible for this study, consisting of 187 patients in the bone cement group and 173 in the non-bone cement group. Ossiculoplasty using bone cement yielded significantly better results, with a combined odds ratio (OR) of 2.03 (95% CI: 1.16–3.55, p = 0.01).</p></div><div><h3>Conclusions</h3><p>The results of this study suggest that the effectiveness of bone cement in ossiculoplasty was greater than that of other materials in chronic otitis media surgery or stapes revision surgery, with a higher number of patients achieving ABG ≤20 dB.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 5","pages":"Pages 316-323"},"PeriodicalIF":0.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142233594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute vertigo with diplopia: that’s central, right? 急性眩晕伴复视:这是中枢性的,对吗?
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.otorri.2024.01.005
Francisco Teixeira-Marques, Roberto Estêvão, Adriana Cunha, Nuno Lousan
{"title":"Acute vertigo with diplopia: that’s central, right?","authors":"Francisco Teixeira-Marques,&nbsp;Roberto Estêvão,&nbsp;Adriana Cunha,&nbsp;Nuno Lousan","doi":"10.1016/j.otorri.2024.01.005","DOIUrl":"10.1016/j.otorri.2024.01.005","url":null,"abstract":"","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 5","pages":"Pages 335-337"},"PeriodicalIF":0.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142233595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraoral ultrasonography: an adjunct in oral onco-surgery 口腔内超声波检查:口腔黏膜手术的辅助手段
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.otorri.2024.01.006
Divyanshi Singh , Neeti Aggarwal , Ravinder S Minhas , Ramesh K Azad , MS Vasanthalakshmi , Jagdeep S Thakur

Objective

To determine the precision and accuracy of intraoral sonography in assessing the depth of invasion in oral cancer.

Material and methods

A prospective study was conducted in 30 cases of oral cancer. Subjects were subjected to computerised tomography and intraoral sonography before surgery. The depth of invasion assessed through clinical palpation and radiological tools was compared with surgical histopathology.

Results

The depth of invasion assessed on clinical palpation and computerized tomography had statistically significant difference with histopathology whereas intraoral sonography didn’t show any difference. The intraoral sonography and computerised tomography had comparable precision and accuracy, with a slight dominance of the computerised tomography in assessing the tumor's depth of invasion greater than 4 mm. However, intraoral sonography was more precise and accurate than computerised tomography in assessing the depth of invasion beyond 10 mm.

Conclusion

Intraoral sonography was found to be a reliable tool in the assessment of the depth of invasion in oral cancer. It can prove beneficial during surgery in achieving tumour-free surgical margins.

材料和方法 对 30 例口腔癌患者进行了前瞻性研究。受试者在手术前接受计算机断层扫描和口腔内超声波检查。结果临床触诊和计算机断层扫描所评估的侵犯深度与组织病理学有显著统计学差异,而口内超声波检查则无任何差异。口腔内声学造影和计算机断层扫描的精确度和准确性相当,在评估肿瘤侵犯深度大于 4 毫米时,计算机断层扫描略占优势。结论口腔超声造影是评估口腔癌浸润深度的可靠工具。结论口腔内声学造影被认为是评估口腔癌侵犯深度的可靠工具,在手术过程中有助于实现无肿瘤手术切缘。
{"title":"Intraoral ultrasonography: an adjunct in oral onco-surgery","authors":"Divyanshi Singh ,&nbsp;Neeti Aggarwal ,&nbsp;Ravinder S Minhas ,&nbsp;Ramesh K Azad ,&nbsp;MS Vasanthalakshmi ,&nbsp;Jagdeep S Thakur","doi":"10.1016/j.otorri.2024.01.006","DOIUrl":"10.1016/j.otorri.2024.01.006","url":null,"abstract":"<div><h3>Objective</h3><p>To determine the precision and accuracy of intraoral sonography in assessing the depth of invasion in oral cancer.</p></div><div><h3>Material and methods</h3><p>A prospective study was conducted in 30 cases of oral cancer. Subjects were subjected to computerised tomography and intraoral sonography before surgery. The depth of invasion assessed through clinical palpation and radiological tools was compared with surgical histopathology.</p></div><div><h3>Results</h3><p>The depth of invasion assessed on clinical palpation and computerized tomography had statistically significant difference with histopathology whereas intraoral sonography didn’t show any difference. The intraoral sonography and computerised tomography had comparable precision and accuracy, with a slight dominance of the computerised tomography in assessing the tumor's depth of invasion greater than 4 mm. However, intraoral sonography was more precise and accurate than computerised tomography in assessing the depth of invasion beyond 10 mm.</p></div><div><h3>Conclusion</h3><p>Intraoral sonography was found to be a reliable tool in the assessment of the depth of invasion in oral cancer. It can prove beneficial during surgery in achieving tumour-free surgical margins.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 5","pages":"Pages 273-280"},"PeriodicalIF":0.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142233627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The association of bacterial biofilm and middle ear mucosa in patients with mucosal chronic suppurative otitis media 粘膜慢性化脓性中耳炎患者的细菌生物膜与中耳粘膜的关系
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-07-01 DOI: 10.1016/j.otorri.2024.02.003
Nahla Nosair , Saad Elzayat , Radwa Elsharaby , Ibrahim A. Abdulghaffar , Haitham H. Elfarargy , Nehal A. Sharaf

Objectives

To evaluate the bacterial biofilm’s role in mucosal chronic suppurative otitis media (CSOM) utilizing scanning electron microscopy (SEM).

Methods

This study involved 123 participating patients with active and inactive mucosal CSOM who underwent tympanomastoid surgery. SEM was used to examine middle ear mucosa biopsies for the development of biofilms. Middle ear discharge or mucosal swabs from patients were cultured to detect any bacterial growth. The biofilm formation was correlated to the culture results.

Results

The biofilm was present in 69.9 % of patients (59% of them were with active mucosal CSOM) and absent in 30.1% of the patients (70% of them were with inactive mucosal CSOM), being more statistically significant in active mucosal CSOM (p-value = 0.003). A correlation that was statistically significant was found between active mucosal CSOM and higher grades (3 and 4) of biofilms (p-value <0.05). The mucosal CSOM type and the results of the culture had a relationship that was statistically significant (p-value <0.001). 60% of patients had positive culture (70% of them were with active mucosal CSOM). There was a statistically significant relation between Pseudomonas aeruginosa bacterial growth and active mucosal CSOM (p-value = 0.004) as well as higher grades of biofilms in mucosal CSOM.

Conclusion

Mucosal CSOM, especially the active type, is a biofilm-related disease. There is a significant relation between the state of mucosal CSOM (active or inactive) and culture results with predominance of Pseudomonas aeruginosa bacterial growth in active mucosal CSOM and in higher grades of biofilms in mucosal CSOM.

目的利用扫描电子显微镜(SEM)评估细菌生物膜在粘膜慢性化脓性中耳炎(CSOM)中的作用。方法本研究涉及 123 名接受鼓室手术的活动性和非活动性粘膜 CSOM 患者。扫描电子显微镜用于检查中耳粘膜活检组织是否出现生物膜。对患者的中耳分泌物或粘膜拭子进行培养,以检测是否有细菌生长。结果69.9%的患者(其中59%为活动性粘膜 CSOM)存在生物膜,30.1%的患者(其中70%为非活动性粘膜 CSOM)不存在生物膜,其中活动性粘膜 CSOM 的生物膜形成具有更显著的统计学意义(p 值 = 0.003)。活动性粘膜 CSOM 与生物膜等级较高(3 级和 4 级)之间存在统计学意义上的相关性(p 值为 0.05)。粘膜 CSOM 类型与培养结果之间的关系具有统计学意义(p 值为 0.001)。60%的患者培养结果呈阳性(其中 70% 为活动性粘膜 CSOM)。铜绿假单胞菌细菌生长与活动性粘膜 CSOM(p 值 = 0.004)以及粘膜 CSOM 中生物膜等级较高之间存在统计学意义。粘膜 CSOM 的状态(活跃或不活跃)与培养结果之间有明显的关系,在活跃的粘膜 CSOM 中,铜绿假单胞菌的生长占主导地位,粘膜 CSOM 中生物膜的等级也较高。
{"title":"The association of bacterial biofilm and middle ear mucosa in patients with mucosal chronic suppurative otitis media","authors":"Nahla Nosair ,&nbsp;Saad Elzayat ,&nbsp;Radwa Elsharaby ,&nbsp;Ibrahim A. Abdulghaffar ,&nbsp;Haitham H. Elfarargy ,&nbsp;Nehal A. Sharaf","doi":"10.1016/j.otorri.2024.02.003","DOIUrl":"https://doi.org/10.1016/j.otorri.2024.02.003","url":null,"abstract":"<div><h3>Objectives</h3><p>To evaluate the bacterial biofilm’s role in mucosal chronic suppurative otitis media (CSOM) utilizing scanning electron microscopy (SEM).</p></div><div><h3>Methods</h3><p>This study involved 123 participating patients with active and inactive mucosal CSOM who underwent tympanomastoid surgery. SEM was used to examine middle ear mucosa biopsies for the development of biofilms. Middle ear discharge or mucosal swabs from patients were cultured to detect any bacterial growth. The biofilm formation was correlated to the culture results.</p></div><div><h3>Results</h3><p>The biofilm was present in 69.9 % of patients (59% of them were with active mucosal CSOM) and absent in 30.1% of the patients (70% of them were with inactive mucosal CSOM), being more statistically significant in active mucosal CSOM (p-value = 0.003). A correlation that was statistically significant was found between active mucosal CSOM and higher grades (3 and 4) of biofilms (p-value &lt;0.05). The mucosal CSOM type and the results of the culture had a relationship that was statistically significant (p-value &lt;0.001). 60% of patients had positive culture (70% of them were with active mucosal CSOM). There was a statistically significant relation between <em>Pseudomonas aeruginosa</em> bacterial growth and active mucosal CSOM (p-value = 0.004) as well as higher grades of biofilms in mucosal CSOM.</p></div><div><h3>Conclusion</h3><p>Mucosal CSOM, especially the active type, is a biofilm-related disease. There is a significant relation between the state of mucosal CSOM (active or inactive) and culture results with predominance of <em>Pseudomonas aeruginosa</em> bacterial growth in active mucosal CSOM and in higher grades of biofilms in mucosal CSOM.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 4","pages":"Pages 244-251"},"PeriodicalIF":0.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141582171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Acta otorrinolaringologica espanola
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1