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Análisis de la supervivencia de los pacientes con tumores malignos de cabeza y cuello diagnosticados durante la pandemia de COVID-19
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-03-01 DOI: 10.1016/j.otorri.2024.10.003
Xavier León , Cristina Valero , Anna Holgado , Cristina Vázquez-López , Rosselin Vásquez , Arnau Parellada , Miquel Quer , Albert Pujol

Objective

The COVID-19 pandemic significantly affected healthcare access worldwide. Few studies have analyzed whether the pandemic negatively impacted patients with head and neck malignant tumors diagnosed during this period. This study aims to determine if there were differences in oncological outcomes between patients diagnosed during the pandemic and those diagnosed previously.

Material and methods

A retrospective study was conducted on patients with malignant head and neck tumors diagnosed during the pandemic and the previous five years at a tertiary center.

Results

The study cohort included 872 patients diagnosed between March 2018 and February 2022. The quarter with the fewest diagnoses was the COVID-4 period (March-2020 to June-2020), coinciding with the strictest lockdown phases. There were no significant changes in patient characteristics or treatment types due to the pandemic. No significant differences in 3-year disease-specific survival were observed between patients diagnosed and treated during the COVID period (March-2020 to February-2021, disease-specific survival 73.0%) and those treated during the previous five years (March-2015 to February-2020, disease-specific survival 70.6%, P = .377).

Conclusions

The COVID-19 pandemic led to a decrease in the number of diagnoses of malignant head and neck tumors during the strictest lockdown phases in our country. However, no statistically significant differences in oncological outcomes were observed as a consequence of the pandemic.
{"title":"Análisis de la supervivencia de los pacientes con tumores malignos de cabeza y cuello diagnosticados durante la pandemia de COVID-19","authors":"Xavier León ,&nbsp;Cristina Valero ,&nbsp;Anna Holgado ,&nbsp;Cristina Vázquez-López ,&nbsp;Rosselin Vásquez ,&nbsp;Arnau Parellada ,&nbsp;Miquel Quer ,&nbsp;Albert Pujol","doi":"10.1016/j.otorri.2024.10.003","DOIUrl":"10.1016/j.otorri.2024.10.003","url":null,"abstract":"<div><h3>Objective</h3><div>The COVID-19 pandemic significantly affected healthcare access worldwide. Few studies have analyzed whether the pandemic negatively impacted patients with head and neck malignant tumors diagnosed during this period. This study aims to determine if there were differences in oncological outcomes between patients diagnosed during the pandemic and those diagnosed previously.</div></div><div><h3>Material and methods</h3><div>A retrospective study was conducted on patients with malignant head and neck tumors diagnosed during the pandemic and the previous five years at a tertiary center.</div></div><div><h3>Results</h3><div>The study cohort included 872 patients diagnosed between March 2018 and February 2022. The quarter with the fewest diagnoses was the COVID-4 period (March-2020 to June-2020), coinciding with the strictest lockdown phases. There were no significant changes in patient characteristics or treatment types due to the pandemic. No significant differences in 3-year disease-specific survival were observed between patients diagnosed and treated during the COVID period (March-2020 to February-2021, disease-specific survival 73.0%) and those treated during the previous five years (March-2015 to February-2020, disease-specific survival 70.6%, <em>P</em> <!-->=<!--> <!-->.377).</div></div><div><h3>Conclusions</h3><div>The COVID-19 pandemic led to a decrease in the number of diagnoses of malignant head and neck tumors during the strictest lockdown phases in our country. However, no statistically significant differences in oncological outcomes were observed as a consequence of the pandemic.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 2","pages":"Pages 106-115"},"PeriodicalIF":0.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sección y reposición del cornete inferior en el diseño de colgajos septales ampliados
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-01-01 DOI: 10.1016/j.otorri.2024.07.004
Juan Ramón Gras-Cabrerizo , María Casasayas-Plass , María Martel-Martin , Katarzyna Kolanczak , Humbert Massegur-Solench , Fernando Muñoz Hernández

Background and objective

Nasoseptal or septal flaps extended to the floor of the fossa and inferior meatus are a resource in the reconstruction of extended endoscopic approaches. We propose the technique of sectioning and repositioning the inferior turbinate to facilitate the design of these extended pedicled flaps.

Material and methods

We evaluated 3 cases operated with a skull base lesion: a craniopharyngioma, a petroclival meningioma and a post-surgical fistula of cerebrospinal fluid in the cribiform plate, in which sectioning and repositioning of the inferior turbinate was performed prior to the design of a septal or nasoseptal flap extended to the floor and inferior meatus. To evaluate the anatomy and function of the inferior turbinate, we analyzed the results of acoustic rhinometry three months after surgery with and without vasoconstrictor.

Results

The pedicled flaps remained visible and vital on endoscopic examination. The area of the C notch obtained by acoustic rhinometry, in the nostril where the turbinate was manipulated, was in all three cases the narrowest area of the nasal cavity. The mean area for the C-notch was 0,34 cm2, 0,74 cm2 y de 0,30 cm2 at a distance from the nostril of 2,20 cm, 2,31 cm and 1,93 cm respectively.

Conclusion

Performing a section and subsequent repositioning of the inferior turbinate, prior to designing an endonasal pedicled flap that includes the mucosa of the floor and inferior meatus, can greatly facilitate obtaining a larger reconstruction flap without affecting the functionality of the inferior turbinate itself.
{"title":"Sección y reposición del cornete inferior en el diseño de colgajos septales ampliados","authors":"Juan Ramón Gras-Cabrerizo ,&nbsp;María Casasayas-Plass ,&nbsp;María Martel-Martin ,&nbsp;Katarzyna Kolanczak ,&nbsp;Humbert Massegur-Solench ,&nbsp;Fernando Muñoz Hernández","doi":"10.1016/j.otorri.2024.07.004","DOIUrl":"10.1016/j.otorri.2024.07.004","url":null,"abstract":"<div><h3>Background and objective</h3><div>Nasoseptal or septal flaps extended to the floor of the fossa and inferior meatus are a resource in the reconstruction of extended endoscopic approaches. We propose the technique of sectioning and repositioning the inferior turbinate to facilitate the design of these extended pedicled flaps.</div></div><div><h3>Material and methods</h3><div>We evaluated 3 cases operated with a skull base lesion: a craniopharyngioma, a petroclival meningioma and a post-surgical fistula of cerebrospinal fluid in the cribiform plate, in which sectioning and repositioning of the inferior turbinate was performed prior to the design of a septal or nasoseptal flap extended to the floor and inferior meatus. To evaluate the anatomy and function of the inferior turbinate, we analyzed the results of acoustic rhinometry three months after surgery with and without vasoconstrictor.</div></div><div><h3>Results</h3><div>The pedicled flaps remained visible and vital on endoscopic examination. The area of the C notch obtained by acoustic rhinometry, in the nostril where the turbinate was manipulated, was in all three cases the narrowest area of the nasal cavity. The mean area for the C-notch was 0,34<!--> <!-->cm<sup>2</sup>, 0,74<!--> <!-->cm<sup>2</sup> y de 0,30<!--> <!-->cm<sup>2</sup> at a distance from the nostril of 2,20<!--> <!-->cm, 2,31<!--> <!-->cm and 1,93<!--> <!-->cm respectively.</div></div><div><h3>Conclusion</h3><div>Performing a section and subsequent repositioning of the inferior turbinate, prior to designing an endonasal pedicled flap that includes the mucosa of the floor and inferior meatus, can greatly facilitate obtaining a larger reconstruction flap without affecting the functionality of the inferior turbinate itself.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 1","pages":"Pages 53-57"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143099211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Normoacusia y discriminación verbal en entornos sonoros reales
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-01-01 DOI: 10.1016/j.otorri.2024.05.005
Adriana Lodeiro Colatosti , Ignacio Pla Gil , Antonio Morant Ventura , Emilia Latorre Monteagudo , Lucía Chacón Aranda , Jaime Marco Algarra
<div><h3>Introduction</h3><div>Human beings are constantly exposed to complex acoustic environments every day, which even pose challenges for individuals with normal hearing. Speech perception relies not only on fixed elements within the acoustic wave but is also influenced by various factors. These factors include speech intensity, environmental noise, the presence of other speakers, individual specific characteristics, spatial separatios of sound sources, ambient reverberation, and audiovisual cues. The objective of this study is twofold: to determine the auditory capacity of normal hearing individuals to discriminate spoken words in real-life acoustic conditions and perform a phonetic analysis of misunderstood spoken words.</div></div><div><h3>Materials and methods</h3><div>This is a descriptive observational cross-sectional study involving 20 normal hearing individuals. Verbal audiometry was conducted in an open-field environment, with sounds masked by simulated real-word acoustic environment at various sound intensity levels. To enhance sound emission, 2D visual images related to the sounds were displayed on a television. We analyzed the percentage of correct answers and performed a phonetic analysis of misunderstood spanish bisyllabic words in each environment.</div></div><div><h3>Results</h3><div>14 women (70%) and 6 men (30%), with an average age of 26<!--> <!-->±<!--> <!-->5,4 years and a mean airway hearing threshold in the right ear of 10,56<!--> <!-->±<!--> <!-->3,52<!--> <!-->dB SPL and in the left ear of 10,12<!--> <!-->±<!--> <!-->2,49<!--> <!-->dB SPL. The percentage of verbal discrimination in the ‘Ocean’ sound environment was 97,2<!--> <!-->±<!--> <!-->5,04%, ‘Restaurant’ was 94<!--> <!-->±<!--> <!-->4,58%, and ‘Traffic’ was 86,2<!--> <!-->±<!--> <!-->9,94% <em>(p</em> <em>=</em> <em>0,000).</em> Regarding the phonetic analysis, the allophones that exhibited statistically significant differences were as follows: [o] <em>(p</em> <em>=</em> <em>0,002)</em> within the group of vocalic phonemes, [n] <em>(p</em> <em>=</em> <em>0,000)</em> of voiced nasal consonants, [ɾ] <em>(</em>p<!--> <em>=</em> <em>0,0016)</em> of voiced fricatives, [b] <em>(p</em> <em>=</em> <em>0,000)</em> and [g] <em>(p</em> <em>=</em> <em>0,045)</em> of voiced stops.</div></div><div><h3>Conclusions</h3><div>The dynamic properties of the acoustic environment can impact the ability of a normal hearing individual to extract information from a voice signal. Our study demonstrates that this ability decreases when the voice signal is masked by one or more simultaneous interfering voices, as observed in a ‘Restaurant’ environment, and when it is masked by a continuous and intense noise environment such as ‘Traffic’. Regarding the phonetic analysis, when the sound environment was composed of continuous-low frequency noise, we found that nasal consonants were particularly challenging to identify. Furthermore, in situations with distracting verbal signals, vowels and vi
{"title":"Normoacusia y discriminación verbal en entornos sonoros reales","authors":"Adriana Lodeiro Colatosti ,&nbsp;Ignacio Pla Gil ,&nbsp;Antonio Morant Ventura ,&nbsp;Emilia Latorre Monteagudo ,&nbsp;Lucía Chacón Aranda ,&nbsp;Jaime Marco Algarra","doi":"10.1016/j.otorri.2024.05.005","DOIUrl":"10.1016/j.otorri.2024.05.005","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Introduction&lt;/h3&gt;&lt;div&gt;Human beings are constantly exposed to complex acoustic environments every day, which even pose challenges for individuals with normal hearing. Speech perception relies not only on fixed elements within the acoustic wave but is also influenced by various factors. These factors include speech intensity, environmental noise, the presence of other speakers, individual specific characteristics, spatial separatios of sound sources, ambient reverberation, and audiovisual cues. The objective of this study is twofold: to determine the auditory capacity of normal hearing individuals to discriminate spoken words in real-life acoustic conditions and perform a phonetic analysis of misunderstood spoken words.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Materials and methods&lt;/h3&gt;&lt;div&gt;This is a descriptive observational cross-sectional study involving 20 normal hearing individuals. Verbal audiometry was conducted in an open-field environment, with sounds masked by simulated real-word acoustic environment at various sound intensity levels. To enhance sound emission, 2D visual images related to the sounds were displayed on a television. We analyzed the percentage of correct answers and performed a phonetic analysis of misunderstood spanish bisyllabic words in each environment.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;14 women (70%) and 6 men (30%), with an average age of 26&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;5,4 years and a mean airway hearing threshold in the right ear of 10,56&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;3,52&lt;!--&gt; &lt;!--&gt;dB SPL and in the left ear of 10,12&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;2,49&lt;!--&gt; &lt;!--&gt;dB SPL. The percentage of verbal discrimination in the ‘Ocean’ sound environment was 97,2&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;5,04%, ‘Restaurant’ was 94&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;4,58%, and ‘Traffic’ was 86,2&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;9,94% &lt;em&gt;(p&lt;/em&gt; &lt;em&gt;=&lt;/em&gt; &lt;em&gt;0,000).&lt;/em&gt; Regarding the phonetic analysis, the allophones that exhibited statistically significant differences were as follows: [o] &lt;em&gt;(p&lt;/em&gt; &lt;em&gt;=&lt;/em&gt; &lt;em&gt;0,002)&lt;/em&gt; within the group of vocalic phonemes, [n] &lt;em&gt;(p&lt;/em&gt; &lt;em&gt;=&lt;/em&gt; &lt;em&gt;0,000)&lt;/em&gt; of voiced nasal consonants, [ɾ] &lt;em&gt;(&lt;/em&gt;p&lt;!--&gt; &lt;em&gt;=&lt;/em&gt; &lt;em&gt;0,0016)&lt;/em&gt; of voiced fricatives, [b] &lt;em&gt;(p&lt;/em&gt; &lt;em&gt;=&lt;/em&gt; &lt;em&gt;0,000)&lt;/em&gt; and [g] &lt;em&gt;(p&lt;/em&gt; &lt;em&gt;=&lt;/em&gt; &lt;em&gt;0,045)&lt;/em&gt; of voiced stops.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions&lt;/h3&gt;&lt;div&gt;The dynamic properties of the acoustic environment can impact the ability of a normal hearing individual to extract information from a voice signal. Our study demonstrates that this ability decreases when the voice signal is masked by one or more simultaneous interfering voices, as observed in a ‘Restaurant’ environment, and when it is masked by a continuous and intense noise environment such as ‘Traffic’. Regarding the phonetic analysis, when the sound environment was composed of continuous-low frequency noise, we found that nasal consonants were particularly challenging to identify. Furthermore, in situations with distracting verbal signals, vowels and vi","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 1","pages":"Pages 11-19"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143099206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
¿Afecta el número de bucles a los resultados de las faringoplastias barbadas? Un estudio comparativo entre dos técnicas
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-01-01 DOI: 10.1016/j.otorri.2024.07.005
Marina Carrasco Llatas , Paula Martínez Ruiz de Apodaca , Elena González Turienzo , Miguel Martínez Moreno , Felipe Domínguez Celis , Giovanni Cammaroto , Claudio Vicini

Introduction

The use of barbed sutures for pharyngoplasty techniques is a new trend in sleep apnea surgery, but little is known about its short-term results depending on the different techniques. The purpose of this study was to analyze the surgical results in two different centers using barbed sutures with different barbed pharyngoplasty techniques.

Material and methods

This is a multicenter retrospective study of patients with obstructive sleep apnea (OSA) undergoing surgery, all of whom underwent pharyngoplasty with barbed suture using a classic or modified technique, which may or may not be associated with other surgical techniques. A univariate and multivariate statistical analysis were performed to assess the relationship of these surgical techniques with surgical success and with different descriptive variables.

Results

The final sample size was 126 patients. A surgical success rate of 39.7% was obtained for a postoperative AHI < 10/h and a 51.6% success rate according to Sher's criteria. A greater proportion of success was observed in the modified barbed pharyngoplasty technique that was not maintained after the multivariate analysis, as with other factors such as age, ODI or the presence of nasal surgery.

Conclusion

Non-resective pharyngoplasty with barbed sutures is an effective technique for the treatment of OSA in selected patients, with both the classic technique and the modified alternatives having good postoperative results, with no differences observed in relation to surgical success between both. More studies are necessary to evaluate the differences between both techniques in more homogeneous groups.
{"title":"¿Afecta el número de bucles a los resultados de las faringoplastias barbadas? Un estudio comparativo entre dos técnicas","authors":"Marina Carrasco Llatas ,&nbsp;Paula Martínez Ruiz de Apodaca ,&nbsp;Elena González Turienzo ,&nbsp;Miguel Martínez Moreno ,&nbsp;Felipe Domínguez Celis ,&nbsp;Giovanni Cammaroto ,&nbsp;Claudio Vicini","doi":"10.1016/j.otorri.2024.07.005","DOIUrl":"10.1016/j.otorri.2024.07.005","url":null,"abstract":"<div><h3>Introduction</h3><div>The use of barbed sutures for pharyngoplasty techniques is a new trend in sleep apnea surgery, but little is known about its short-term results depending on the different techniques. The purpose of this study was to analyze the surgical results in two different centers using barbed sutures with different barbed pharyngoplasty techniques.</div></div><div><h3>Material and methods</h3><div>This is a multicenter retrospective study of patients with obstructive sleep apnea (OSA) undergoing surgery, all of whom underwent pharyngoplasty with barbed suture using a classic or modified technique, which may or may not be associated with other surgical techniques. A univariate and multivariate statistical analysis were performed to assess the relationship of these surgical techniques with surgical success and with different descriptive variables.</div></div><div><h3>Results</h3><div>The final sample size was 126 patients. A surgical success rate of 39.7% was obtained for a postoperative AHI &lt;<!--> <!-->10/h and a 51.6% success rate according to Sher's criteria. A greater proportion of success was observed in the modified barbed pharyngoplasty technique that was not maintained after the multivariate analysis, as with other factors such as age, ODI or the presence of nasal surgery.</div></div><div><h3>Conclusion</h3><div>Non-resective pharyngoplasty with barbed sutures is an effective technique for the treatment of OSA in selected patients, with both the classic technique and the modified alternatives having good postoperative results, with no differences observed in relation to surgical success between both. More studies are necessary to evaluate the differences between both techniques in more homogeneous groups.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 1","pages":"Pages 25-30"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143099207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resultados en vida real sobre la mejoría en la calidad de vida de los pacientes con poliposis nasal tratados con mepolizumab. Estudio RINOSUR
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-01-01 DOI: 10.1016/j.otorri.2024.08.001
Juan Maza-Solano , Juan Aguilar-Cantador , María Dolores Noguerol-Pérez , María Soledad Sánchez-Torices , María Jesús Martínez-Martínez , María José Gámiz-Maroto
Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by nasal obstruction, reduced sense of smell, rhinorrhea, and facial pain for more than 12 weeks, significantly affecting quality of life (QoL), especially in patients with NSAID-exacerbated respiratory disease (NERD). Initial treatment includes intranasal corticosteroids and nasal irrigations, followed by systemic corticosteroids (SC) in severe cases, as well as endoscopic sinus surgery (ESS) and biological agents. Mepolizumab, a monoclonal antibody against IL-5, has been shown to reduce eosinophilic inflammation in CRSwNP. This study evaluates the improvement in quality of life of patients with CRSwNP treated with mepolizumab before December 2023, recorded by the RINOSUR group.
A retrospective observational multicenter cohort study is presented in adult patients with severe asthma and concomitant CRSwNP, treated with mepolizumab 100 mg. Variables such as sex, asthma, allergies, NERD, corticosteroid dependence, and serum eosinophil count were recorded. All patients underwent nasal endoscopy and completed the SNOT22 questionnaire. Therapeutic response was evaluated at 12 months.
Out of 143 patients recruited, only 28.6% had the necessary data. 61% were women with a mean age of 55 years. All were corticosteroid-dependent and had required at least one ESS. A 22% reduction in SC cycles was observed, and no patient required revision surgery in the 12 months following treatment. The SNOT22 score was reduced by 53 points, and serum eosinophilia also showed a significant decrease.
Mepolizumab is effective in treating severe uncontrolled CRSwNP, improving QoL and reducing dependence on systemic corticosteroids. Its activity is monitored by peripheral blood eosinophilia. Consistency in data collection is crucial to evaluate efficacy and manage the disease.
{"title":"Resultados en vida real sobre la mejoría en la calidad de vida de los pacientes con poliposis nasal tratados con mepolizumab. Estudio RINOSUR","authors":"Juan Maza-Solano ,&nbsp;Juan Aguilar-Cantador ,&nbsp;María Dolores Noguerol-Pérez ,&nbsp;María Soledad Sánchez-Torices ,&nbsp;María Jesús Martínez-Martínez ,&nbsp;María José Gámiz-Maroto","doi":"10.1016/j.otorri.2024.08.001","DOIUrl":"10.1016/j.otorri.2024.08.001","url":null,"abstract":"<div><div>Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by nasal obstruction, reduced sense of smell, rhinorrhea, and facial pain for more than 12 weeks, significantly affecting quality of life (QoL), especially in patients with NSAID-exacerbated respiratory disease (NERD). Initial treatment includes intranasal corticosteroids and nasal irrigations, followed by systemic corticosteroids (SC) in severe cases, as well as endoscopic sinus surgery (ESS) and biological agents. Mepolizumab, a monoclonal antibody against IL-5, has been shown to reduce eosinophilic inflammation in CRSwNP. This study evaluates the improvement in quality of life of patients with CRSwNP treated with mepolizumab before December 2023, recorded by the RINOSUR group.</div><div>A retrospective observational multicenter cohort study is presented in adult patients with severe asthma and concomitant CRSwNP, treated with mepolizumab 100<!--> <!-->mg. Variables such as sex, asthma, allergies, NERD, corticosteroid dependence, and serum eosinophil count were recorded. All patients underwent nasal endoscopy and completed the SNOT22 questionnaire. Therapeutic response was evaluated at 12 months.</div><div>Out of 143 patients recruited, only 28.6% had the necessary data. 61% were women with a mean age of 55 years. All were corticosteroid-dependent and had required at least one ESS. A 22% reduction in SC cycles was observed, and no patient required revision surgery in the 12 months following treatment. The SNOT22 score was reduced by 53 points, and serum eosinophilia also showed a significant decrease.</div><div>Mepolizumab is effective in treating severe uncontrolled CRSwNP, improving QoL and reducing dependence on systemic corticosteroids. Its activity is monitored by peripheral blood eosinophilia. Consistency in data collection is crucial to evaluate efficacy and manage the disease.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 1","pages":"Pages 58-64"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143099210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Meningoencefalocele transetmoidal: morfología endoscópica y radiológica
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-01-01 DOI: 10.1016/j.otorri.2024.09.004
Ainhoa García-LLiberós , Moisés Sánchez-Pardo , Enrique Zapater-Latorre
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引用次数: 0
Parálisis de Bell y covid-19: estudio de cohortes de comparación histórica
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-01-01 DOI: 10.1016/j.otorri.2024.07.006
Natalia Arango , María Jesús Rojas-Lechuga , Jiwei Chen , Francisco Larrosa , Berta Alegre , Isabel Vilaseca

Introduction

During the SARS-CoV-2 pandemic, immune-mediated neurological events have been described in patients vaccinated against the virus or who have overcome the disease. Among these events is idiopathic peripheral facial palsy or Bell's palsy.

Objectives

To study the incidence of Bell's palsy in the ENT emergency department of a tertiary hospital in Catalonia during the SARS-CoV-2 pandemic.

Methods

Retrospective historical cohort comparison study of patients diagnosed with Bell's palsy between January 2018 and December 2021. Crude incidence rates were calculated as the total number of events divided by person time at risk per 100.000 person-years. Observed (2020, 2021) and historical (2018, 2019) rates were compared using standardized incidence rates with corresponding 95% confidence intervals.

Results

Of the total number of ENT emergency department visits from 2018 to 2021 (22.658), there were 247 cases of Bell's palsy. The incidence rate of Bell's palsy in the pre-pandemic group was 12,2 and 10,9 per 100.000 person-years for 2018 and 2019, respectively. The 2020 standardized incidence rate of Bell's palsy was 0,70 (95% CI: 0,49-1,01) and 1,25 (95% CI: 0,93-1,67) for 2021. No significant differences were evident between the 2 groups.

Conclusion

In our cohort, no association was found between vaccination or COVID-19 infection and the development of Bell's palsy.
{"title":"Parálisis de Bell y covid-19: estudio de cohortes de comparación histórica","authors":"Natalia Arango ,&nbsp;María Jesús Rojas-Lechuga ,&nbsp;Jiwei Chen ,&nbsp;Francisco Larrosa ,&nbsp;Berta Alegre ,&nbsp;Isabel Vilaseca","doi":"10.1016/j.otorri.2024.07.006","DOIUrl":"10.1016/j.otorri.2024.07.006","url":null,"abstract":"<div><h3>Introduction</h3><div>During the SARS-CoV-2 pandemic, immune-mediated neurological events have been described in patients vaccinated against the virus or who have overcome the disease. Among these events is idiopathic peripheral facial palsy or Bell's palsy.</div></div><div><h3>Objectives</h3><div>To study the incidence of Bell's palsy in the ENT emergency department of a tertiary hospital in Catalonia during the SARS-CoV-2 pandemic.</div></div><div><h3>Methods</h3><div>Retrospective historical cohort comparison study of patients diagnosed with Bell's palsy between January 2018 and December 2021. Crude incidence rates were calculated as the total number of events divided by person time at risk per 100.000 person-years. Observed (2020, 2021) and historical (2018, 2019) rates were compared using standardized incidence rates with corresponding 95% confidence intervals.</div></div><div><h3>Results</h3><div>Of the total number of ENT emergency department visits from 2018 to 2021 (22.658), there were 247 cases of Bell's palsy. The incidence rate of Bell's palsy in the pre-pandemic group was 12,2 and 10,9 per 100.000 person-years for 2018 and 2019, respectively. The 2020 standardized incidence rate of Bell's palsy was 0,70 (95% CI: 0,49-1,01) and 1,25 (95% CI: 0,93-1,67) for 2021. No significant differences were evident between the 2<!--> <!-->groups.</div></div><div><h3>Conclusion</h3><div>In our cohort, no association was found between vaccination or COVID-19 infection and the development of Bell's palsy.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 1","pages":"Pages 31-36"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143099305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nuevo nomenclátor de Otorrinolaringología de la SEORL-CCC - Anestesiología (SEDAR). Versión ejecutiva 2024
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-01-01 DOI: 10.1016/j.otorri.2024.04.002
Irene López Delgado , Manuel Bernal-Sprekelsen

Purpose

After the publication of the new standardized nomenclature for the specialty of Otorhinolaryngology in 2021, a joint adaptation was carried out with the Spanish Society of Anesthesiology, Resuscitation and Pain Therapy (SEDAR), creating an executive version. In this version, the Anesthesia groups are added for those procedures that require it and, in addition, the number of acts is reduced to facilitate its implementation in the daily basis healthcare activity. The aim of this article is to update the definitive executive version of the nomenclature for the specialty of Otolaryngology.

Methods

The nomenclature published in 2021 was updated, reducing the number of acts and procedures. For this purpose, a grouping of procedures similar in description and in order and ranking has been made. Those procedures that have been grouped together have received a new description that reflects all the acts included in order to facilitate its coding but respecting the essence of the proposal of the complete version of the 2021 nomenclature. Subsequently, the private medicine committee of SEDAR has assigned the anaesthetic act for those procedures that may require it. In addition, a provisional code has been assigned for those acts that are new with respect to the latest version approved by the OMC, which allows their numerical identification.

Results

The executive version of the nomenclature presents a total of 234 medical acts, compared to 395 listed in the 2021 version, which are distributed by OMC classification groups and ENT subspecialties. One-hundred and fourteen procedures maintain the original OMC code, with some modifications in the description of the medical act. Other procedures also performed by ENT but listed elsewhere were kept with their same description and group and assigned OMC codes. The remaining 120 procedures are new proposals made by the scientific society and its subspecialty committees.

Conclusions

The executive version of the new nomenclature of Otorhinolaryngology proposed by the SEORL-CCC and SEDAR updates the one from 2021 and is the only one valid in our specialty for its use in the private healthcare daily practice. The reduction of medical procedures, without losing richness or modifications of the surgical groups, and the allocation of the anesthesia scales, facilitates its implementation, and provides the highest standards of quality and clinical timelines.
{"title":"Nuevo nomenclátor de Otorrinolaringología de la SEORL-CCC - Anestesiología (SEDAR). Versión ejecutiva 2024","authors":"Irene López Delgado ,&nbsp;Manuel Bernal-Sprekelsen","doi":"10.1016/j.otorri.2024.04.002","DOIUrl":"10.1016/j.otorri.2024.04.002","url":null,"abstract":"<div><h3>Purpose</h3><div>After the publication of the new standardized nomenclature for the specialty of Otorhinolaryngology in 2021, a joint adaptation was carried out with the Spanish Society of Anesthesiology, Resuscitation and Pain Therapy (SEDAR), creating an executive version. In this version, the Anesthesia groups are added for those procedures that require it and, in addition, the number of acts is reduced to facilitate its implementation in the daily basis healthcare activity. The aim of this article is to update the definitive executive version of the nomenclature for the specialty of Otolaryngology.</div></div><div><h3>Methods</h3><div>The nomenclature published in 2021 was updated, reducing the number of acts and procedures. For this purpose, a grouping of procedures similar in description and in order and ranking has been made. Those procedures that have been grouped together have received a new description that reflects all the acts included in order to facilitate its coding but respecting the essence of the proposal of the complete version of the 2021 nomenclature. Subsequently, the private medicine committee of SEDAR has assigned the anaesthetic act for those procedures that may require it. In addition, a provisional code has been assigned for those acts that are new with respect to the latest version approved by the OMC, which allows their numerical identification.</div></div><div><h3>Results</h3><div>The executive version of the nomenclature presents a total of 234 medical acts, compared to 395 listed in the 2021 version, which are distributed by OMC classification groups and ENT subspecialties. One-hundred and fourteen procedures maintain the original OMC code, with some modifications in the description of the medical act. Other procedures also performed by ENT but listed elsewhere were kept with their same description and group and assigned OMC codes. The remaining 120 procedures are new proposals made by the scientific society and its subspecialty committees.</div></div><div><h3>Conclusions</h3><div>The executive version of the new nomenclature of Otorhinolaryngology proposed by the SEORL-CCC and SEDAR updates the one from 2021 and is the only one valid in our specialty for its use in the private healthcare daily practice. The reduction of medical procedures, without losing richness or modifications of the surgical groups, and the allocation of the anesthesia scales, facilitates its implementation, and provides the highest standards of quality and clinical timelines.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 1","pages":"Pages 37-49"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143099209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estudio prospectivo de la localización en pacientes con hipoacusia unilateral y asimétrica tratados con implante coclear 对接受人工耳蜗治疗的单侧和非对称听力损失患者进行定位的前瞻性研究。
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-01-01 DOI: 10.1016/j.otorri.2024.05.002
María Aragonés Redó , Ignacio Pla Gil , Tomàs Pérez-Carbonell , Clara Espina González , Antonio Morant Ventura , Jaime Marco Algarra

Background and Objective

Sound localization plays a crucial role in our daily lives, enabling us to recognize voices, respond to alarming situations, avoid dangers, and navigate towards specific signals. However, this ability is compromised in patients with Single-Sided Deafness (SSD) and Asymmetric Hearing Loss (AHL), negatively impacting their daily functioning. The main objective of the study was to quantify the degree of sound source localization in patients with single-sided deafness or asymmetric hearing loss using a Cochlear Implant (CI) and to compare between the two subgroups.

Materials and Methods

This was a prospective, longitudinal, observational, single-center study involving adult patients diagnosed with profound unilateral or asymmetric sensorineural hearing loss who underwent cochlear implantation. Sound localization was assessed in a chamber equipped with seven speakers evenly distributed from -90° to 90°. Stimuli were presented at 1,000 Hz and intensities of 65 dB, 70 dB, and 75 dB. Each stimulus was presented only once per speaker, totaling 21 presentations. The number of correct responses at different intensities was recorded, and angular error in degrees was calculated to determine the mean angular distance between the patient-indicated speaker and the speaker presenting the stimulus. Both assessments were conducted preoperatively without a cochlear implant and two years post-implantation.

Results

The total sample comprised 20 patients, with 9 assigned to the SSD group and 11 to the AHL group. The Preoperative Pure Tone Average (PTA) in free field was 31.7 dB in the SSD group and 41.8 dB in the AHL group. There was a statistically significant improvement in sound localization ability and angular error with the use of the cochlear implant at all intensities in both SSD and AHL subgroups.

Conclusions

Cochlear implantation in patients with SSD and AHL enhances sound localization, reducing mean angular error and increasing the number of correct sound localization responses.
{"title":"Estudio prospectivo de la localización en pacientes con hipoacusia unilateral y asimétrica tratados con implante coclear","authors":"María Aragonés Redó ,&nbsp;Ignacio Pla Gil ,&nbsp;Tomàs Pérez-Carbonell ,&nbsp;Clara Espina González ,&nbsp;Antonio Morant Ventura ,&nbsp;Jaime Marco Algarra","doi":"10.1016/j.otorri.2024.05.002","DOIUrl":"10.1016/j.otorri.2024.05.002","url":null,"abstract":"<div><h3>Background and Objective</h3><div>Sound localization plays a crucial role in our daily lives, enabling us to recognize voices, respond to alarming situations, avoid dangers, and navigate towards specific signals. However, this ability is compromised in patients with Single-Sided Deafness (SSD) and Asymmetric Hearing Loss (AHL), negatively impacting their daily functioning. The main objective of the study was to quantify the degree of sound source localization in patients with single-sided deafness or asymmetric hearing loss using a Cochlear Implant (CI) and to compare between the two subgroups.</div></div><div><h3>Materials and Methods</h3><div>This was a prospective, longitudinal, observational, single-center study involving adult patients diagnosed with profound unilateral or asymmetric sensorineural hearing loss who underwent cochlear implantation. Sound localization was assessed in a chamber equipped with seven speakers evenly distributed from -90° to 90°. Stimuli were presented at 1,000<!--> <!-->Hz and intensities of 65<!--> <!-->dB, 70<!--> <!-->dB, and 75<!--> <!-->dB. Each stimulus was presented only once per speaker, totaling 21 presentations. The number of correct responses at different intensities was recorded, and angular error in degrees was calculated to determine the mean angular distance between the patient-indicated speaker and the speaker presenting the stimulus. Both assessments were conducted preoperatively without a cochlear implant and two years post-implantation.</div></div><div><h3>Results</h3><div>The total sample comprised 20 patients, with 9 assigned to the SSD group and 11 to the AHL group. The Preoperative Pure Tone Average (PTA) in free field was 31.7<!--> <!-->dB in the SSD group and 41.8<!--> <!-->dB in the AHL group. There was a statistically significant improvement in sound localization ability and angular error with the use of the cochlear implant at all intensities in both SSD and AHL subgroups.</div></div><div><h3>Conclusions</h3><div>Cochlear implantation in patients with SSD and AHL enhances sound localization, reducing mean angular error and increasing the number of correct sound localization responses.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 1","pages":"Pages 1-10"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141390604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laryngeal chondrosarcoma, a 30-year series
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-01-01 DOI: 10.1016/j.otorri.2024.07.001
Patrícia Fernandes Lopes , Joana Nascimento , Gustavo Rocha , Catarina Tinoco , Ana Hebe , Pedro Montalvão , Miguel Magalhães

Introduction and objectives

Laryngeal chondrosarcoma is a rare laryngeal pathology arising from cartilaginous structures and is predominantly found in the cricoid cartilage. This study investigates its presentation, treatment modalities and patient outcomes.

Patients or materials and methods

Retrospective study of laryngeal chondrosarcoma cases followed from 1992 to 2022 in the Otorhinolaryngology department of a cancer center - Instituto Português de Oncologia de Lisboa. Statistical analysis was made with Microsoft Excel® and SPSS®.

Results

We identified 16 cases, of which two-thirds were male, with an average age of 59.6 years, and only 24% of them had a history of smoking. The commonest presentation was indolent dysphonia and/or dyspnea, and the posterior arch of the cricoid cartilage was the most affected place. Although histopathological studies after biopsy were often inconclusive, surgery emerged as the first-line of treatment for all patients. Larynx microsurgery with lesion debulking was the most frequent surgical approach (47%) followed by partial laryngectomy (24%). Neither adjuvant radiotherapy (RT) nor chemotherapy was administered in any of the cases. There was residual tumor in 23% of the cases so half of these patients were in watchful waiting while the other part underwent further microsurgery or total laryngectomy. Only one patient with recurrence received RT. Disease-specific survival rate at 1 and 5 years was 97% and 91%, respectively.

Conclusion

Laryngeal chondrosarcoma etiology is still unknown and is effectively treated with surgery, with a generally favorable prognosis. The main concern lies in its propensity to relapse, highlighting the importance of watchful follow-up.
{"title":"Laryngeal chondrosarcoma, a 30-year series","authors":"Patrícia Fernandes Lopes ,&nbsp;Joana Nascimento ,&nbsp;Gustavo Rocha ,&nbsp;Catarina Tinoco ,&nbsp;Ana Hebe ,&nbsp;Pedro Montalvão ,&nbsp;Miguel Magalhães","doi":"10.1016/j.otorri.2024.07.001","DOIUrl":"10.1016/j.otorri.2024.07.001","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Laryngeal chondrosarcoma is a rare laryngeal pathology arising from cartilaginous structures and is predominantly found in the cricoid cartilage. This study investigates its presentation, treatment modalities and patient outcomes.</div></div><div><h3>Patients or materials and methods</h3><div>Retrospective study of laryngeal chondrosarcoma cases followed from 1992 to 2022 in the Otorhinolaryngology department of a cancer center - Instituto Português de Oncologia de Lisboa. Statistical analysis was made with Microsoft Excel® and SPSS®.</div></div><div><h3>Results</h3><div>We identified 16 cases, of which two-thirds were male, with an average age of 59.6 years, and only 24% of them had a history of smoking. The commonest presentation was indolent dysphonia and/or dyspnea, and the posterior arch of the cricoid cartilage was the most affected place. Although histopathological studies after biopsy were often inconclusive, surgery emerged as the first-line of treatment for all patients. Larynx microsurgery with lesion debulking was the most frequent surgical approach (47%) followed by partial laryngectomy (24%). Neither adjuvant radiotherapy (RT) nor chemotherapy was administered in any of the cases. There was residual tumor in 23% of the cases so half of these patients were in watchful waiting while the other part underwent further microsurgery or total laryngectomy. Only one patient with recurrence received RT. Disease-specific survival rate at 1 and 5 years was 97% and 91%, respectively.</div></div><div><h3>Conclusion</h3><div>Laryngeal chondrosarcoma etiology is still unknown and is effectively treated with surgery, with a generally favorable prognosis. The main concern lies in its propensity to relapse, highlighting the importance of watchful follow-up.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 1","pages":"Pages 20-24"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143099208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Acta otorrinolaringologica espanola
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