Acta otorrinolaringologica espanola最新文献

英文中文

Parálisis de Bell y COVID-19: un estudio de cohorte con comparación de tasas históricas: comentario 贝尔瘫痪和COVID-19：历史比率比较队列研究：评论

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-03-01 DOI: 10.1016/j.otorri.2024.11.001

Hinpetch Daungsupawong , Viroj Wiwanitkit

引用次数: 0

Complications after fine-needle aspiration cytology and core-needle biopsy in benign head & neck neoplasms 良性头颈部肿瘤细针穿刺细胞学及芯针活检术后并发症分析

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-03-01 DOI: 10.1016/j.otorri.2024.09.002

Alfonso Rodriguez-Urzay , Maria Landa-Garmendia , Jon Alexander Sistiaga-Suarez , Jose Angel González-Garcá , Ehkiñe Larruscain-Sarasola , Mikel Beristain , Carlos Miguel Chiesa-Estomba

Introduction

Benign neck masses are one of the most common causes of clinical consultation in head & neck (H&N) clinics. Fine needle aspiration cytology (FNAC) and core needle biopsy (CNB) have become among the main strategies for the diagnostic work-up of palpable and non-palpable neck lumps. Moreover, numerous studies have established the safety, high diagnostic yield, and added value of image-guided H&N biopsies, which play an important role in diagnosis, staging, and treatment planning, and can obviate the need for surgery for many patients. Nonetheless, despite the success of both techniques, there is a lack of recent studies regarding their safety and associated complication rates.

Material & method

A retrospective analysis was performed of prospective data on patients undergoing ultrasound-guided FNAC or CNB for benign H&N disease (e.g., salivary gland benign tumors, branchial cleft cyst, thyroglossal duct, cyst, lipoma, or neurinoma) between June 2016 and June 2021 in a tertiary university hospital.

Results

Overall, 192 patients were included (105 [54.7%] men and 87 [45.3%] women). The Kolmogorov-Smirnov test indicated that our data were normally distributed (p = 0.452). The mean age of enrolled patients was 54 ± 10 (range: 18–87). The anatomical site most commonly affected was a major salivary gland (74%). Regarding incidence and type of complications, nine (4.7%) patients experienced complications, infection being the most common problem. The risk of complications was highest in patients with branchial cleft cysts who had undergone FNAC (p = 0.028). Overall, the risk of complications was not associated with the type of technique (p = 0.603; OR: 0.942; 95% confidence interval = 0.245–3.624).

Conclusion

According to our results, FNAC and CNB are generally safe and reliable procedures in the diagnostic work-up of H&N lumps. Nevertheless, physicians should be aware of certain risks associated with these procedures.

颈部良性肿块是临床求诊的最常见原因之一。颈部（H&；N）诊所细针抽吸细胞学（FNAC）和核心针活检（CNB）已成为可触及和不可触及颈部肿块诊断工作的主要策略。此外，大量研究表明，图像引导下的H&；N活检具有安全性、高诊断率和附加价值，在诊断、分期和治疗计划中发挥着重要作用，许多患者无需手术。然而，尽管这两种技术都取得了成功，但最近缺乏关于其安全性和相关并发症发生率的研究。材料,方法回顾性分析2016年6月至2021年6月某三级大学附属医院超声引导下行H&；N良性疾病（如唾液腺良性肿瘤、鳃裂囊肿、甲状舌管、囊肿、脂肪瘤、神经鞘瘤）FNAC或CNB的前瞻性资料。结果共纳入192例患者，其中男性105例（54.7%），女性87例（45.3%）。Kolmogorov-Smirnov检验表明我们的数据是正态分布（p = 0.452）。入组患者的平均年龄为54±10岁（范围18-87岁）。最常受影响的解剖部位是大唾液腺（74%）。关于并发症的发生率和类型，9例（4.7%）患者出现并发症，感染是最常见的问题。鳃裂囊肿行FNAC的患者出现并发症的风险最高（p = 0.028）。总的来说，并发症的风险与手术方式无关(p = 0.603；OR: 0.942;95%置信区间= 0.245-3.624)。结论FNAC和CNB是诊断H&；N肿块安全可靠的检查方法。然而，医生应该意识到与这些手术相关的某些风险。

{"title":"Complications after fine-needle aspiration cytology and core-needle biopsy in benign head & neck neoplasms","authors":"Alfonso Rodriguez-Urzay , Maria Landa-Garmendia , Jon Alexander Sistiaga-Suarez , Jose Angel González-Garcá , Ehkiñe Larruscain-Sarasola , Mikel Beristain , Carlos Miguel Chiesa-Estomba","doi":"10.1016/j.otorri.2024.09.002","DOIUrl":"10.1016/j.otorri.2024.09.002","url":null,"abstract":"<div><h3>Introduction</h3><div>Benign neck masses are one of the most common causes of clinical consultation in head & neck (H&N) clinics. Fine needle aspiration cytology (FNAC) and core needle biopsy (CNB) have become among the main strategies for the diagnostic work-up of palpable and non-palpable neck lumps. Moreover, numerous studies have established the safety, high diagnostic yield, and added value of image-guided H&N biopsies, which play an important role in diagnosis, staging, and treatment planning, and can obviate the need for surgery for many patients. Nonetheless, despite the success of both techniques, there is a lack of recent studies regarding their safety and associated complication rates.</div></div><div><h3>Material & method</h3><div>A retrospective analysis was performed of prospective data on patients undergoing ultrasound-guided FNAC or CNB for benign H&N disease (e.g., salivary gland benign tumors, branchial cleft cyst, thyroglossal duct, cyst, lipoma, or neurinoma) between June 2016 and June 2021 in a tertiary university hospital.</div></div><div><h3>Results</h3><div>Overall, 192 patients were included (105 [54.7%] men and 87 [45.3%] women). The Kolmogorov-Smirnov test indicated that our data were normally distributed (<em>p</em> = 0.452). The mean age of enrolled patients was 54 ± 10 (range: 18–87). The anatomical site most commonly affected was a major salivary gland (74%). Regarding incidence and type of complications, nine (4.7%) patients experienced complications, infection being the most common problem. The risk of complications was highest in patients with branchial cleft cysts who had undergone FNAC (<em>p</em> = 0.028). Overall, the risk of complications was not associated with the type of technique (<em>p</em> = 0.603; OR: 0.942; 95% confidence interval = 0.245–3.624).</div></div><div><h3>Conclusion</h3><div>According to our results, FNAC and CNB are generally safe and reliable procedures in the diagnostic work-up of H&N lumps. Nevertheless, physicians should be aware of certain risks associated with these procedures.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 2","pages":"Pages 71-75"},"PeriodicalIF":0.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reconstrucción del labio inferior con el colgajo de Karapandzic o el colgajo de Colmenero: descripción de resultados 用Karapandzic或Colmenero环重建下唇：结果说明

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-03-01 DOI: 10.1016/j.otorri.2024.10.001

Anna Sumarroca , Carmen Vega , Susana López , Andreas Leidinger , Gabriel Pedemonte , Xavier León , José Miguel Costa-González

Background and objective

Reconstruction of medium and large oncological defects of the lower lip must preserve the functionality and aesthetics of the area and is usually solved with local pedicled flaps, rarely compared between them. The aim of this study is to analyse our case series of lower lip reconstruction using the Karapandzic flap or the Colmenero flap, and to describe their techniques and results.

Materials and methods

We performed a retrospective review of patients who underwent lower lip resection and reconstruction with the Colmenero flap or Karapandzic flap during the period 2015-2022 with a minimum follow-up time of more than one year. The defect size, treatment, complications, reinterventions and final outcome were analysed.

Results

A total of 22 patients underwent surgery: 13 of them were reconstructed with Karapandzic flaps, all bilateral (26 flaps) and with a mean defect size of 4.05 cm (2.9- 6.5 cm); 9 patients were reconstructed with Colmenero flaps, of which 4 bilaterally (13 flaps), with a mean defect size of 4.16 cm (3-7.5 cm). All flaps were viable and all complications (5 among Karapandzic flaps and 4 among Colmenero flaps), mostly minor, were resolved. There were no statistically significant differences between the sizes of the reconstructed defects or between the complications of the 2 flaps. All patients had a total oral intake of food, no speech defects and a good final aesthetic result.

Conclusions

The surgical techniques of lower lip reconstruction with the Karapandzic flap or the Colmenero flap are very reliable, simple in design, with similar and very satisfactory functional and aesthetic results.

背景和目的下唇大中型肿瘤性缺损的重建必须保留该区域的功能性和美观性，通常采用局部带蒂皮瓣解决，很少对两者进行比较。本研究旨在分析我们使用卡拉潘季奇皮瓣或科尔梅内罗皮瓣进行下唇重建的系列病例，并描述它们的技术和效果。材料和方法我们对 2015-2022 年期间接受下唇切除术并使用科尔梅内罗皮瓣或卡拉潘季奇皮瓣进行重建的患者进行了回顾性回顾，随访时间至少超过一年。结果共有 22 名患者接受了手术：其中13名患者采用卡拉潘季奇皮瓣重建，均为双侧（26个皮瓣），平均缺损大小为4.05厘米（2.9-6.5厘米）；9名患者采用科尔梅内罗皮瓣重建，其中4名患者为双侧（13个皮瓣），平均缺损大小为4.16厘米（3-7.5厘米）。所有皮瓣均存活，所有并发症（卡拉潘季奇皮瓣 5 例，科尔梅内罗皮瓣 4 例）均已解决，其中大部分为轻微并发症。重建缺损的大小和两种皮瓣的并发症之间没有明显的统计学差异。结论：使用卡拉潘季奇皮瓣或科尔梅内罗皮瓣重建下唇的手术技术非常可靠，设计简单，具有相似且非常令人满意的功能和美学效果。

{"title":"Reconstrucción del labio inferior con el colgajo de Karapandzic o el colgajo de Colmenero: descripción de resultados","authors":"Anna Sumarroca , Carmen Vega , Susana López , Andreas Leidinger , Gabriel Pedemonte , Xavier León , José Miguel Costa-González","doi":"10.1016/j.otorri.2024.10.001","DOIUrl":"10.1016/j.otorri.2024.10.001","url":null,"abstract":"<div><h3>Background and objective</h3><div>Reconstruction of medium and large oncological defects of the lower lip must preserve the functionality and aesthetics of the area and is usually solved with local pedicled flaps, rarely compared between them. The aim of this study is to analyse our case series of lower lip reconstruction using the Karapandzic flap or the Colmenero flap, and to describe their techniques and results.</div></div><div><h3>Materials and methods</h3><div>We performed a retrospective review of patients who underwent lower lip resection and reconstruction with the Colmenero flap or Karapandzic flap during the period 2015-2022 with a minimum follow-up time of more than one year. The defect size, treatment, complications, reinterventions and final outcome were analysed.</div></div><div><h3>Results</h3><div>A total of 22 patients underwent surgery: 13 of them were reconstructed with Karapandzic flaps, all bilateral (26 flaps) and with a mean defect size of 4.05cm (2.9- 6.5cm); 9 patients were reconstructed with Colmenero flaps, of which 4 bilaterally (13 flaps), with a mean defect size of 4.16cm (3-7.5cm). All flaps were viable and all complications (5 among Karapandzic flaps and 4 among Colmenero flaps), mostly minor, were resolved. There were no statistically significant differences between the sizes of the reconstructed defects or between the complications of the 2flaps. All patients had a total oral intake of food, no speech defects and a good final aesthetic result.</div></div><div><h3>Conclusions</h3><div>The surgical techniques of lower lip reconstruction with the Karapandzic flap or the Colmenero flap are very reliable, simple in design, with similar and very satisfactory functional and aesthetic results.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 2","pages":"Pages 83-90"},"PeriodicalIF":0.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

By-pass venoso (vena yugular interna-vena yugular externa) en paciente con vaciamiento radical bilateral 双侧根治性排空患者的旁通静脉（内颈静脉-外颈静脉）

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-03-01 DOI: 10.1016/j.otorri.2024.10.005

Diego Tébar Calo , Pablo Verges Fort , Simon Brotons Durban , Ángel Pla Mocholi , Bosco Vendrell Marques

引用次数: 0

The effect of interleukin-33 expression on prognosis in patients with nasopharyngeal carcinoma 白细胞介素-33表达对鼻咽癌患者预后的影响

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-03-01 DOI: 10.1016/j.otorri.2024.01.010

İbrahim Arslan , Hatice Yılmazçoban , Hülya Eyigör , Canan Sadullahoğlu , Derya Salim Kıvrak , Gözde Akgün , Ömer Tarık Selçuk

Introduction

Interleukin-33 (IL-33) is a newly defined inflammatory cytokine that is a member of the interleukin-1 (IL-1) gene family. This cytokine is expressed in structural cells, such as the vascular endothelium, bronchial epithelial cells, keratinocytes, epithelial cells of the stomach, and fibroblastic reticular cells of lymphoid tissues. Several studies suggest that IL-33 plays a role in head-and-neck cancer. The aim of this study was to retrospectively examine IL-33 expression in nasopharyngeal carcinoma (NPC) and to evaluate its relationship between clinicopathological characteristics and prognosis.

Methods

In this monocentric, retrospective analysis, the data of 43 cases diagnosed with primary NPC and 20 cases with normal nasopharyngeal tissue (diagnosed between 2014 and 2020) were evaluated regarding the relationship between the immunohistochemically analyzed IL-33 expression status and corresponding clinicopathological parameters.

Results

The mean age was 56.9 years. The majority (67.4%) of the patients had an early tumor stage (T1–T2). IL-33 expression was positive in 56% of the cases. The five-year overall survival rate was 77% for all patients, 90% for the patients with positive IL-33 expression, and 55% for those without IL-33 expression (p = 0.008, univariate analysis). In multivariate analysis, IL-33 expression was shown to be the only independent prognostic marker for nasopharyngeal carcinoma (p = 0.014).

Conclusion

This retrospective study showed that IL-33 expression could be considered an independent factor affecting positively prognosis in NPC.

白细胞介素-33 （IL-33）是一种新定义的炎症细胞因子，是白细胞介素-1 （IL-1）基因家族的成员。该细胞因子在结构细胞中表达，如血管内皮、支气管上皮细胞、角化细胞、胃上皮细胞和淋巴组织的成纤维网状细胞。几项研究表明，IL-33在头颈癌中起作用。本研究旨在回顾性检测IL-33在鼻咽癌（NPC）中的表达，并探讨其与临床病理特征和预后的关系。方法采用单中心回顾性分析方法，对2014 ~ 2020年诊断的43例原发性鼻咽癌患者和20例正常鼻咽癌患者的数据进行免疫组化分析，分析IL-33表达水平与相应临床病理参数的关系。结果患者平均年龄56.9岁。绝大多数（67.4%）患者为肿瘤早期（T1-T2）。56%的病例IL-33表达阳性。所有患者的5年总生存率为77%，IL-33表达阳性患者为90%，IL-33不表达患者为55% （p = 0.008，单变量分析）。多因素分析显示，IL-33表达是鼻咽癌唯一独立的预后指标（p = 0.014）。结论本回顾性研究显示IL-33的表达可被认为是影响鼻咽癌阳性预后的独立因素。

{"title":"The effect of interleukin-33 expression on prognosis in patients with nasopharyngeal carcinoma","authors":"İbrahim Arslan , Hatice Yılmazçoban , Hülya Eyigör , Canan Sadullahoğlu , Derya Salim Kıvrak , Gözde Akgün , Ömer Tarık Selçuk","doi":"10.1016/j.otorri.2024.01.010","DOIUrl":"10.1016/j.otorri.2024.01.010","url":null,"abstract":"<div><h3>Introduction</h3><div>Interleukin-33 (IL-33) is a newly defined inflammatory cytokine that is a member of the interleukin-1 (IL-1) gene family. This cytokine is expressed in structural cells, such as the vascular endothelium, bronchial epithelial cells, keratinocytes, epithelial cells of the stomach, and fibroblastic reticular cells of lymphoid tissues. Several studies suggest that IL-33 plays a role in head-and-neck cancer. The aim of this study was to retrospectively examine IL-33 expression in nasopharyngeal carcinoma (NPC) and to evaluate its relationship between clinicopathological characteristics and prognosis.</div></div><div><h3>Methods</h3><div>In this monocentric, retrospective analysis, the data of 43 cases diagnosed with primary NPC and 20 cases with normal nasopharyngeal tissue (diagnosed between 2014 and 2020) were evaluated regarding the relationship between the immunohistochemically analyzed IL-33 expression status and corresponding clinicopathological parameters.</div></div><div><h3>Results</h3><div>The mean age was 56.9 years. The majority (67.4%) of the patients had an early tumor stage (T1–T2). IL-33 expression was positive in 56% of the cases. The five-year overall survival rate was 77% for all patients, 90% for the patients with positive IL-33 expression, and 55% for those without IL-33 expression (<em>p</em> = 0.008, univariate analysis). In multivariate analysis, IL-33 expression was shown to be the only independent prognostic marker for nasopharyngeal carcinoma (<em>p</em> = 0.014).</div></div><div><h3>Conclusion</h3><div>This retrospective study showed that IL-33 expression could be considered an independent factor affecting positively prognosis in NPC.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 2","pages":"Pages 76-82"},"PeriodicalIF":0.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subcutaneous emphysema secondary to Eustachian tube dilation 继发于耳咽管扩张的皮下肺气肿

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-03-01 DOI: 10.1016/j.otorri.2024.07.003

José M. Sala-Vivé Gallego , Laura Acevedo Ortiz , Xavier Galindo Ortegó

引用次数: 0

Otorhinolaryngological manifestations of autoinflammatory diseases. Systematic review 自身炎症性疾病的耳鼻喉科表现。系统综述

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-03-01 DOI: 10.1016/j.otorri.2024.09.001

María Victoria Mallo-Miranda , Carmelo Morales-Angulo

Objectives

To detail the main otorhinolaryngological manifestations of autoinflammatory diseases, aiming to contribute to early diagnosis and treatment.

Data sources

Searches were conducted in PubMed, LILACS, Cochrane Library.

Review methods

A systematic review of the medical literature on autoinflammatory diseases was conducted to identify characteristic head and neck manifestations, using PRISMA criteria. Observational studies or systematic reviews with a minimum of 10 cases per disease were included. Qualitative synthesis and a risk assessment were carried out.

Results

Our review included 29 articles that met the inclusion criteria, with 10 to 486 patients per study. Autoinflammatory diseases with characteristic head and neck manifestations included VEXAS syndrome (auricular, nasal, or laryngotracheal chondritis), NPRL3-AID (hearing loss), NPRL12-AID (cervical lymphadenopathies, hearing loss and oral ulcers), HIDSs syndrome (painful cervical nodes and oral ulcers), haploinsufficiency A20 (oral ulcers), TRAPS (pharyngitis, aphthous stomatitis, periorbital edema, and cervical lymphadenopathies), Behcet’s disease (oral and pharyngeal ulcers), PFAPA syndrome (recurrent tonsillitis, oral ulcers, and painful cervical adenopathies), Kawasaki disease (cervical nodes, pharyngitis and changes in oral mucosa) and undefined periodic fever (pharyngitis, oral ulcers, and painful cervical nodes).

Conclusion

Given their complex diagnosis and unique head and neck manifestations, otolaryngologists must be well-versed in these diseases for early detection and treatment. ENT specialists should consider the possibility of an autoinflammatory disease when encountering symptoms such as auricular, nasal, or laryngeal chondritis, recurrent oral ulcers, painful inflammatory lymphadenopathies, periorbital edema, recurrent pharyngitis, or hearing loss within the context of compatible systemic conditions.

目的探讨自身炎症性疾病的主要耳鼻喉科表现，为早期诊断和治疗提供依据。数据来源检索PubMed， LILACS, Cochrane Library。回顾方法系统回顾自身炎症性疾病的医学文献，采用PRISMA标准确定特征性头颈部表现。每种疾病至少纳入10例的观察性研究或系统评价。进行了定性综合和风险评估。结果我们的综述纳入了29篇符合纳入标准的文章，每项研究纳入10至486例患者。以头颈部为特征性表现的自身炎症性疾病包括：VEXAS综合征（耳部、鼻部或喉气管软骨炎）、NPRL3-AID（听力损失）、NPRL12-AID（颈部淋巴结病、听力损失和口腔溃疡）、hids综合征（颈部淋巴结痛和口腔溃疡）、单倍功能不全A20（口腔溃疡）、TRAPS（咽炎、口腔炎、眼周水肿和颈部淋巴结病）、白塞病（口腔和咽部溃疡）、PFAPA综合征（复发性扁桃体炎、口腔溃疡和疼痛性宫颈腺病）、川崎病（宫颈淋巴结、咽炎和口腔黏膜改变）和不明周期性发热（咽炎、口腔溃疡和宫颈淋巴结疼痛）。结论耳鼻喉科医师因其复杂的诊断和独特的头颈部表现，必须对其有所了解，以便及早发现和治疗。耳鼻喉专科医生在遇到耳部、鼻部或喉部软骨炎、复发性口腔溃疡、疼痛性炎症性淋巴结病、眶周水肿、复发性咽炎或听力损失等症状时，应考虑自身炎症性疾病的可能性。

{"title":"Otorhinolaryngological manifestations of autoinflammatory diseases. Systematic review","authors":"María Victoria Mallo-Miranda , Carmelo Morales-Angulo","doi":"10.1016/j.otorri.2024.09.001","DOIUrl":"10.1016/j.otorri.2024.09.001","url":null,"abstract":"<div><h3>Objectives</h3><div>To detail the main otorhinolaryngological manifestations of autoinflammatory diseases, aiming to contribute to early diagnosis and treatment.</div></div><div><h3>Data sources</h3><div>Searches were conducted in PubMed, LILACS, Cochrane Library.</div></div><div><h3>Review methods</h3><div>A systematic review of the medical literature on autoinflammatory diseases was conducted to identify characteristic head and neck manifestations, using PRISMA criteria. Observational studies or systematic reviews with a minimum of 10 cases per disease were included. Qualitative synthesis and a risk assessment were carried out.</div></div><div><h3>Results</h3><div>Our review included 29 articles that met the inclusion criteria, with 10 to 486 patients per study. Autoinflammatory diseases with characteristic head and neck manifestations included VEXAS syndrome (auricular, nasal, or laryngotracheal chondritis), NPRL3-AID (hearing loss), NPRL12-AID (cervical lymphadenopathies, hearing loss and oral ulcers), HIDSs syndrome (painful cervical nodes and oral ulcers), haploinsufficiency A20 (oral ulcers), TRAPS (pharyngitis, aphthous stomatitis, periorbital edema, and cervical lymphadenopathies), Behcet’s disease (oral and pharyngeal ulcers), PFAPA syndrome (recurrent tonsillitis, oral ulcers, and painful cervical adenopathies), Kawasaki disease (cervical nodes, pharyngitis and changes in oral mucosa) and undefined periodic fever (pharyngitis, oral ulcers, and painful cervical nodes).</div></div><div><h3>Conclusion</h3><div>Given their complex diagnosis and unique head and neck manifestations, otolaryngologists must be well-versed in these diseases for early detection and treatment. ENT specialists should consider the possibility of an autoinflammatory disease when encountering symptoms such as auricular, nasal, or laryngeal chondritis, recurrent oral ulcers, painful inflammatory lymphadenopathies, periorbital edema, recurrent pharyngitis, or hearing loss within the context of compatible systemic conditions.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 2","pages":"Pages 116-129"},"PeriodicalIF":0.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of remote programming of cochlear implants under challenging conditions 挑战性条件下人工耳蜗远程编程的评价

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-03-01 DOI: 10.1016/j.otorri.2024.10.002

Luis Lassaletta , Miryam Calvino , Isabel Sánchez-Cuadrado , Giovanni Danesi , Ilaria Patelli , Michela Zana , Íñigo Ruiz de Erenchun-Lasa , Manuela del Carmen Zapata , Eva María Muñoz Yuste , Daniel Schaudel , Cherisse Mark , Gionata Conni , Pedro Luis Sarría Echegaray , Guillermo til-Pérez , Isaac David Gutiérrez Pérez , Elena Muñoz Pascual

Introduction and objectives

During the strained period of the COVID-19 pandemic, an international multi-centric clinical pilot study of remote cochlear implant fitting (remote programming) took place with the primary aim of evaluating the satisfaction of patients and practitioners with this procedure.

Materials and methods

Cochlear implant users and clinical practitioners from clinics in Spain and Italy completed a questionnaire to evaluate their experience regarding their satisfaction with the procedure and with its efficacy.

Results

54 responses were collected from 48 users and 42 responses were collected from 9 clinical practitioners. Practitioners were able to perform both remote fitting and remote telemetry. They rated their satisfaction with the procedure highly, with a median value of 9.5/10. Over 90% were satisfied with the results of the procedure, and all who responded would be willing to use remote programming again. Practitioners also rated the technical performance highly. Users rated their satisfaction with the procedure with a median value of 8/10. The great majority of users would be willing to undergo remote programming again (81.3%), and most would recommend the procedure to other users (74%).

Conclusions

Remote programming is a well-received procedure among both clinical practitioners and cochlear implant users, and offers a useful alternative when in-person visits are not practical or not possible, as was the case during the pandemic.

在2019冠状病毒病大流行的紧张时期，开展了一项远程人工耳蜗植入（远程编程）的国际多中心临床试点研究，主要目的是评估患者和医生对该手术的满意度。材料和方法来自西班牙和意大利诊所的人工耳蜗使用者和临床从业人员完成了一份调查问卷，以评估他们对手术及其疗效的满意度。结果48名用户共收到54份回复，9名临床医生共收到42份回复。从业人员能够进行远程装配和远程遥测。他们对手术的满意度评价很高，中位数为9.5/10。超过90%的人对程序的结果感到满意，所有回应的人都愿意再次使用远程编程。从业人员也高度评价了技术性能。用户对手术的满意度中位数为8/10。绝大多数用户愿意再次进行远程编程（81.3%），大多数用户会向其他用户推荐该程序（74%）。远程编程在临床医生和人工耳蜗使用者中都是一种广受欢迎的程序，并且在不实际或不可能亲自访问时提供了一种有用的替代方案，例如在大流行期间。

{"title":"Evaluation of remote programming of cochlear implants under challenging conditions","authors":"Luis Lassaletta , Miryam Calvino , Isabel Sánchez-Cuadrado , Giovanni Danesi , Ilaria Patelli , Michela Zana , Íñigo Ruiz de Erenchun-Lasa , Manuela del Carmen Zapata , Eva María Muñoz Yuste , Daniel Schaudel , Cherisse Mark , Gionata Conni , Pedro Luis Sarría Echegaray , Guillermo til-Pérez , Isaac David Gutiérrez Pérez , Elena Muñoz Pascual","doi":"10.1016/j.otorri.2024.10.002","DOIUrl":"10.1016/j.otorri.2024.10.002","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>During the strained period of the COVID-19 pandemic, an international multi-centric clinical pilot study of remote cochlear implant fitting (remote programming) took place with the primary aim of evaluating the satisfaction of patients and practitioners with this procedure.</div></div><div><h3>Materials and methods</h3><div>Cochlear implant users and clinical practitioners from clinics in Spain and Italy completed a questionnaire to evaluate their experience regarding their satisfaction with the procedure and with its efficacy.</div></div><div><h3>Results</h3><div>54 responses were collected from 48 users and 42 responses were collected from 9 clinical practitioners. Practitioners were able to perform both remote fitting and remote telemetry. They rated their satisfaction with the procedure highly, with a median value of 9.5/10. Over 90% were satisfied with the results of the procedure, and all who responded would be willing to use remote programming again. Practitioners also rated the technical performance highly. Users rated their satisfaction with the procedure with a median value of 8/10. The great majority of users would be willing to undergo remote programming again (81.3%), and most would recommend the procedure to other users (74%).</div></div><div><h3>Conclusions</h3><div>Remote programming is a well-received procedure among both clinical practitioners and cochlear implant users, and offers a useful alternative when in-person visits are not practical or not possible, as was the case during the pandemic.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 2","pages":"Pages 91-98"},"PeriodicalIF":0.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vena yugular interna fenestrada atravesada por nervio espinal 开窗内臀静脉穿过脊柱神经

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-03-01 DOI: 10.1016/j.otorri.2024.09.003

Belén Clemente Cuartero , Pedro Díaz de Cerio Canduela , Ricardo Fernández-Valadés Gámez

引用次数: 0

Postsurgical hypoparathyroidism: Identification of the high-risk patient. A comparison between the ATA protocol and the SEORL-CCC/SEEN consensus 术后甲状旁腺功能减退：高危患者的识别。ATA协议与SEORL-CCC/SEEN共识的比较

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola

Pub Date : 2025-03-01 DOI: 10.1016/j.otorri.2024.10.004

Miriam García Lerma, Laura Rodrigáñez Riesco, Antonio del Palacio Muñoz, Ricardo Bernáldez Millán, Laura del Río Arroyo, Javier Gavilán Bouzas, Alejandro Castro Calvo

Introduction

Parathyroid hormone (PTH) levels are the most reliable parameter to identify patients with a high risk of post-thyroidectomy hypoparathyroidism. The American Thyroid Association (ATA) developed a consensus where postoperative iPTH (PTHpost) <15 pg/mL suggests a significant risk for hypoparathyroidism. The Spanish Society of Otolaryngology and Head & Neck Surgery (SEORL-CCC) identifies high-risk patients as those with a decrease of preoperative-postoperative PTH levels (PTHdecr) ≥80%. A comparison of the accuracy of both protocols is made.

Materials and methods

An analysis was conducted on all patients who underwent total or completion thyroidectomy over 10 years. A preoperative PTH (PTHpre) and a postoperative PTH (PTHpost) sample were collected. Postsurgical hypoparathyroidism was defined as the presence of hypocalcemia signs or symptoms, or calcium lower than 7 mg/dL in serum levels or 0.95 mmol/L in ionic levels. No patient received treatment without meeting our definition.

Results

711 patients were included. 19% of patients suffered from hypoparathyroidism. The PTHdecr demonstrated a ROC curve with an AUC of 0.98. iPTHpost demonstrated a ROC curve with an AUC of 0.97. The PTHdecr was found to have a statistically superior AUC compared to the PTHpost (p = 0.002). Considering cutoff levels of 80% for iPTHdecr and 15 pg/mL for PTHpost, no statistical differences were found between the sensitivity of both protocols (93% and 95% respectively), but the same cutoff levels showed a superior specificity of PTHdecr (95%) than PTHpost (86%).

Conclusions

SEORL-CCC protocol, which relies on PTHdecr, has demonstrated superior diagnostic accuracy. The cutoff level used showed a superior specificity without sacrificing its sensitivity.

甲状旁腺激素（PTH）水平是识别甲状腺切除术后甲状旁腺功能低下高风险患者最可靠的参数。美国甲状腺协会（ATA）达成共识，术后iPTH (PTHpost)≤15 pg/mL提示甲状旁腺功能减退的显著风险。西班牙耳鼻咽喉及头部学会；颈外科（SEORL-CCC）将术前-术后PTH水平（PTHdecr）下降≥80%的高危患者确定为高危患者。比较了两种方案的准确性。材料与方法对10年内全部或完全甲状腺切除术的患者进行分析。采集术前PTH （PTHpre）和术后PTH （PTHpost）标本。术后甲状旁腺功能减退被定义为存在低钙症状或体征，或血清钙水平低于7 mg/dL或离子水平低于0.95 mmol/L。没有患者接受不符合我们定义的治疗。结果共纳入711例患者。19%的患者出现甲状旁腺功能减退。pthdec的ROC曲线AUC为0.98。iPTHpost的ROC曲线AUC为0.97。与PTHpost相比，PTHdecr的AUC具有统计学优势（p = 0.002）。考虑到iPTHdecr的临界值为80%，PTHpost的临界值为15 pg/mL，两种方案的敏感性之间没有统计学差异（分别为93%和95%），但相同的临界值表明PTHdecr（95%）优于PTHpost（86%）。结论基于PTHdecr的seorl - ccc方案具有较好的诊断准确性。所使用的截止水平在不牺牲其灵敏度的情况下显示出优越的特异性。

{"title":"Postsurgical hypoparathyroidism: Identification of the high-risk patient. A comparison between the ATA protocol and the SEORL-CCC/SEEN consensus","authors":"Miriam García Lerma, Laura Rodrigáñez Riesco, Antonio del Palacio Muñoz, Ricardo Bernáldez Millán, Laura del Río Arroyo, Javier Gavilán Bouzas, Alejandro Castro Calvo","doi":"10.1016/j.otorri.2024.10.004","DOIUrl":"10.1016/j.otorri.2024.10.004","url":null,"abstract":"<div><h3>Introduction</h3><div>Parathyroid hormone (PTH) levels are the most reliable parameter to identify patients with a high risk of post-thyroidectomy hypoparathyroidism. The American Thyroid Association (ATA) developed a consensus where postoperative iPTH (PTHpost) <15pg/mL suggests a significant risk for hypoparathyroidism. The Spanish Society of Otolaryngology and Head & Neck Surgery (SEORL-CCC) identifies high-risk patients as those with a decrease of preoperative-postoperative PTH levels (PTHdecr) ≥80%. A comparison of the accuracy of both protocols is made.</div></div><div><h3>Materials and methods</h3><div>An analysis was conducted on all patients who underwent total or completion thyroidectomy over 10 years. A preoperative PTH (PTHpre) and a postoperative PTH (PTHpost) sample were collected. Postsurgical hypoparathyroidism was defined as the presence of hypocalcemia signs or symptoms, or calcium lower than 7mg/dL in serum levels or 0.95mmol/L in ionic levels. No patient received treatment without meeting our definition.</div></div><div><h3>Results</h3><div>711 patients were included. 19% of patients suffered from hypoparathyroidism. The PTHdecr demonstrated a ROC curve with an AUC of 0.98. iPTHpost demonstrated a ROC curve with an AUC of 0.97. The PTHdecr was found to have a statistically superior AUC compared to the PTHpost (p=0.002). Considering cutoff levels of 80% for iPTHdecr and 15pg/mL for PTHpost, no statistical differences were found between the sensitivity of both protocols (93% and 95% respectively), but the same cutoff levels showed a superior specificity of PTHdecr (95%) than PTHpost (86%).</div></div><div><h3>Conclusions</h3><div>SEORL-CCC protocol, which relies on PTHdecr, has demonstrated superior diagnostic accuracy. The cutoff level used showed a superior specificity without sacrificing its sensitivity.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 2","pages":"Pages 99-105"},"PeriodicalIF":0.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

首页上一页

下一页尾页

类型

全部化学•材料生命科学医学物理工程技术环境•农林材料科学地球科学法学管理学化学环境科学与生态学计算机科学教育学经济学农林科学人文科学生物学数学物理与天体物理心理学综合性期刊其他工业工程理学历史学农学文学信息工程

数据库

全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley

期刊

Acta otorrinolaringologica espanola

全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.

﹀