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Anatomical variations of sphenoid sinus on cone beam computed tomography 锥束计算机体层摄影在蝶窦解剖上的变化
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-07-01 DOI: 10.1016/j.otorri.2025.512229
Patrícia Fernandes Lopes , Tatiana Carvalho , Miguel Furtado

Introduction

The surgical approach to the sphenoid sinus (SS) is one of the most challenging aspects of endoscopic surgery due to its proximity to critical structures. To minimize risks, computed tomography (CT) aids in navigational guidance. Although cone beam computed tomography (CBCT) has lower contrast resolution, it offers improved precision, reduced radiation exposure, and faster imaging, making it a viability as a preoperative tool.

Methods

We randomly selected 75 patients from 707 who underwent CBCT between January and December 2023. Two observers evaluated SS anatomy with consensus. Statistical analyses were conducted using Excel® and Jamovi®.

Results

Anatomical variations were documented, with prevalence rates as follows: sphenoethmoidal cell (15%); optic nerve (ON) protrusion (21%) and dehiscence (4%); internal carotid artery (ICA) protrusion (31%) and dehiscence (0%); vidian canal (VC) protrusion (39%) and dehiscence (6%); foramen rotundum (FR) protrusion (23%) and dehiscence (5%); anterior clinoid process (ACP) pneumatization (20%); pterygoid process (PP) pneumatization (33%); conchal (1%), presellar (7%), sellar (36%) and postsellar type (56%) SS; and intersphenoidal septum (47%). Statistically significant correlations were observed between ACP pneumatization and ON protrusion (p < 0.001) and dehiscence (p = 0.018), and ICA protrusion (p = 0.001). PP pneumatization was significantly correlated with VC protrusion (p < 0.001) and dehiscence (p = 0.011), and foramen rotundum protrusion (p < 0.001).

Discussion/Conclusion

Our CBCT findings largely aligned with CT data in existing literature. Due to its faster acquisition and lower radiation exposure, CBCT shows potential as a preoperative evaluation method for assessing the SS.
蝶窦(SS)的手术入路是内镜手术中最具挑战性的方面之一,因为它靠近关键结构。为了降低风险,计算机断层扫描(CT)有助于导航。尽管锥形束计算机断层扫描(CBCT)的对比度分辨率较低,但它提供了更高的精度、更少的辐射暴露和更快的成像,使其成为一种可行的术前工具。方法从2023年1月至12月期间接受CBCT检查的707例患者中随机选择75例。两名观察员一致评价SS解剖。采用Excel®和Jamovi®进行统计分析。结果在解剖学上存在差异,患病率如下:蝶筛细胞(15%);视神经(ON)突出(21%)和裂裂(4%);颈内动脉(ICA)突出(31%)和开裂(0%);viddian canal (VC)突出(39%)和开裂(6%);圆孔(FR)突出(23%)和开裂(5%);前斜突(ACP)通气(20%);翼状突(PP)气化(33%);鼻窦型(1%)、鞍前型(7%)、鞍前型(36%)和鞍后型(56%);蝶窦间隔(47%)。ACP气化与ON突出有统计学意义(p <;裂隙(p = 0.018), ICA突出(p = 0.001)。PP通气与VC突出显著相关(p <;0.001)、裂孔突出(p = 0.011)、圆孔突出(p <;0.001)。讨论/结论:我们的CBCT结果与现有文献中的CT数据基本一致。由于其采集速度快,辐射暴露低,CBCT有潜力作为术前评估SS的方法。
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引用次数: 0
A look at DFNB16 markers and their application in the genetic study of hearing loss in Iranian deaf families DFNB16标记及其在伊朗失聪家庭听力损失遗传学研究中的应用
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-07-01 DOI: 10.1016/j.otorri.2025.512230
Reihane Fazeli-Jezei , Elham Davoudi-Dehaghani

Introduction

The study of the gene encoding stereocilin (STRC) is complicated by the presence of a pseudogene (STRCP1) with over 98.8% similarity. We analysed the linkage between hearing loss and the DFNB16 locus in consanguineous Iranian deaf families.

Materials and methods

A review of previous studies on the DFNB16 locus was conducted to find the smallest regions linked to the STRC gene with no reported crossing-overs, as well as an investigation of short tandem repeat (STR) and single nucleotide polymorphism (SNP) markers of the DFNB16 locus using the UCSC, NCBI, and Iranome databases. A total of 36 consanguineous families with at least two individuals affected by autosomal recessive non-syndromic hearing loss (ARNSHL) were selected for the study. Autozygosity mapping was performed using tag SNP markers linked to the DFNB16 locus.

Results

The investigation showed that SNPs are more appropriate for linkage studies in these families than STR markers. In this study, 12 distinct haplotypes were identified, with frequencies ranging from 3.1% to 21.8%. Based on the haplotype analysis results and the autozygosity mapping, no linkage was found in any families analysed.

Discussion

In genetic studies of deafness in multi-affected consanguineous families, preliminary screening by autozygosity mapping can be helpful, especially for complicated genes like STRC. If the distance between STRs and the gene under study is significant, SNPs can provide a more effective solution. This study can potentially help to develop a more cost-effective method for genetic testing of STRC-related deafness.
由于存在一个相似度超过98.8%的假基因STRCP1,对stereocilin (STRC)编码基因的研究变得复杂。我们分析了伊朗近亲耳聋家庭中听力损失与DFNB16基因座之间的联系。材料和方法对DFNB16基因座的既往研究进行了回顾,寻找与STRC基因相关的最小区域,并使用UCSC、NCBI和Iranome数据库对DFNB16基因座的短串联重复(STR)和单核苷酸多态性(SNP)标记进行了调查。共有36个近亲家庭,至少有2人患有常染色体隐性非综合征性听力损失(ARNSHL)。使用与DFNB16位点相关的标签SNP标记进行自合子定位。结果SNPs比STR标记更适合于这些家族的连锁研究。在这项研究中,鉴定出12种不同的单倍型,频率从3.1%到21.8%不等。根据单倍型分析结果和自合子图谱,在所有分析的家族中均未发现连锁。在多发病近亲家族耳聋的遗传研究中,通过自合子作图进行初步筛选是有帮助的,特别是对于STRC等复杂基因。如果STRs与所研究基因之间的距离很大,snp可以提供更有效的解决方案。这项研究可能有助于开发一种更具成本效益的方法,用于strc相关耳聋的基因检测。
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引用次数: 0
Estratificación de la severidad de la sialoadenitis obstructiva crónica en función de su impacto en la calidad de vida 按对生活质量的影响对慢性阻塞性脊柱炎严重程度进行分层
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-07-01 DOI: 10.1016/j.otorri.2025.512223
William Aragonés Sanzen-Baker , José Miguel Villacampa Aubá , Ignacio Alcalá Rueda , Jessica Mireya Santillán Coello , Gonzalo Díaz Tapia , Carlos Cenjor Español , Álvaro Sánchez Barrueco

Introduction

Chronic Obstructive Sialadenitis (COS) is a debilitating condition characterized by recurrent inflammation of the salivary glands due to excretory obstruction, significantly impacting patients’ quality of life (QoL). The COS Quality of Life Questionnaire (COSQ) has been validated to evaluate QoL in affected patients and to monitor changes post-treatment.

Materials and methods

This study included two patient groups with COS-affected glands. The first group of 342 patients completed the COSQ before minimally invasive surgery, while the second group of 215 patients completed both the COSQ and a Visual Analog Scale (VAS). Scores were analyzed and stratified into four severity categories: mild, moderate, severe, and very severe, based on COSQ outcomes.

Results

COSQ scores were distributed as follows: mild (12.87%), moderate (37.13%), severe (34.5%), and very severe (15.21%). A significant correlation was observed between COSQ and VAS scores, particularly in the moderate and severe categories. Stratification allowed for identification of patients with severe symptoms, aiding in tailored management.

Conclusion

The COSQ effectively assesses QoL in COS patients and aids in stratifying severity. This stratification can guide clinicians in developing personalized treatment strategies, monitoring disease progression, and evaluating treatment outcomes.
慢性阻塞性涎腺炎(COS)是一种使人衰弱的疾病,其特征是由于排泄障碍引起的唾液腺复发性炎症,严重影响患者的生活质量。已验证COS生活质量问卷(COSQ)用于评估受影响患者的生活质量并监测治疗后的变化。材料和方法本研究包括两组cos影响腺体的患者。第一组342例患者在微创术前完成COSQ,第二组215例患者同时完成COSQ和视觉模拟评分(VAS)。根据COSQ结果,对评分进行分析并将其分为轻度、中度、重度和极重度四个严重类别。结果scosq评分分为轻度(12.87%)、中度(37.13%)、重度(34.5%)、极重度(15.21%)。在COSQ和VAS评分之间观察到显著的相关性,特别是在中度和重度分类中。分层可以识别严重症状的患者,有助于量身定制的管理。结论COSQ能有效评价COS患者的生活质量,有助于病情的分级。这种分层可以指导临床医生制定个性化的治疗策略,监测疾病进展,并评估治疗结果。
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引用次数: 0
Características acústicas de la voz de los niños usuarios de implante coclear 人工耳蜗使用者儿童声音的声学特征
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-07-01 DOI: 10.1016/j.otorri.2025.512238
Faustino Núñez-Batalla , Ainoa Álvarez , Isabel Sandoval , Paula Sánchez , Estefania Díaz-Fresno , Jorge Javier Ramírez , Maite Guntín , Justo Gómez , Jose Luis Llorente , Verónica Suárez-Martínez

Introduction

Congenital profound bilateral hearing loss prevents the correct development of speech and voice. This study assesses certain acoustic parameters of the voice in order to determine their normality in the implanted population.

Method

Two population groups were studied. A control group consisting of 42 healthy pediatric patients, 22 boys and 20 girls, and a group of 22 pediatric patients, 11 boys and 11 girls with congenital profound hearing loss implanted bilaterally.
The variables median pitch, CPPS, jitter rap and shimmer apq5 were evaluated in an isolated phonation exercise and another in connected speech for the phoneme /a/ with the PRAAT program. Student's t-test and Wilcoxcon tests were applied.

Results

Significant intergroup differences were obtained for all variables in the vowel extracted from connected speech, but not in the sustained vowel. The hearing-impaired population showed some significant differences in the intra-group analysis. The experimental group showed better results in the vocal quality parameters, particularly jitter, shimmer and CPPS showed statistically significant differences.

Conclusion

Early bilateral implantation allows the cochlear implant user to approximate his acoustic values to normative values in terms of pitch, stability, quality and articulatory precision.
先天性重度双侧听力损失妨碍语言和声音的正确发育。本研究评估某些声学参数的声音,以确定他们的正常植入人群。方法对两组人群进行研究。对照组42例,男22例,女20例;对照组22例,男11例,女11例,先天性深度听力损失患儿双侧植入术。使用PRAAT程序对音素/a/在孤立发声练习和连接语音中评估变量中位音、CPPS、抖动rap和闪烁apq5。采用学生t检验和Wilcoxcon检验。结果从连接语音中提取的元音各变量组间差异显著,但持续元音组间差异不显著。听障人群在组内分析中有显著差异。实验组在音质参数上表现较好,尤其是抖动、闪音、CPPS差异有统计学意义。结论早期双侧人工耳蜗植入术可使人工耳蜗使用者在音高、稳定性、音质和发音精度等方面的声学值接近正常值。
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引用次数: 0
Isolated frontal sinus angiofibroma with external forehead deformity: A case report 孤立性额窦血管纤维瘤合并额外畸形1例
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-07-01 DOI: 10.1016/j.otorri.2025.512227
Ali Tawfik, Ahmed Musaad Abd-Elfattah, Hisham Atef Ebada, Ahmad Muhammad Al-Arman, Donia Usama Hamza, Elsharawy Kamal
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引用次数: 0
¿Dónde se dirige la medicina del sueño? Un análisis de las unidades multidisciplinares en España 睡眠医学的方向是什么?西班牙多学科单位分析
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-07-01 DOI: 10.1016/j.otorri.2025.512234
Laura Rodriguez Alcala , Carlos O’Connor-Reina , Carlos Egea , F. Javier Puertas , Milagros Merino , Marina Carrasco , Jose Maria Ignacio , Peter Baptista , Guillermo Plaza
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引用次数: 0
External ear affection in multiple myeloma 多发性骨髓瘤对外耳的影响
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-07-01 DOI: 10.1016/j.otorri.2025.512228
João Tavares Correia, Isabel Silva-Carvalho, Luís Meireles
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引用次数: 0
Complicaciones respiratorias en pacientes intervenidos por cáncer de cavidad oral, faringe y laringe en un hospital terciario 三级医院口腔癌、咽喉癌和咽喉癌患者的呼吸道并发症
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-07-01 DOI: 10.1016/j.otorri.2025.512236
Marta Zabaleta López , Belén Clemente Cuartero , Pedro Díaz de Cerio Canduela , Nisa Boukichou Addelkader , Javier Ugedo Urruela

Background and objective

The incidence of head and neck cancer (HNC) is directly related to tobacco and alcohol consumption, which explains why patients with HNC often present comorbidities, with chronic obstructive pulmonary disease (COPD) being an example. This condition is underdiagnosed, and various authors have demonstrated how its presence increases the incidence of respiratory complications in patients undergoing surgery for HNC.
We conducted a study aimed at evaluating respiratory complications in patients undergoing surgery for HNC at the San Pedro University Hospital (HUSP).

Materials and methods

A retrospective and descriptive study was conducted, including all adult patients diagnosed with oral cavity, pharyngeal, or laryngeal carcinoma who underwent surgery at the HUSP in Logroño between 2018 and 2021. Sociodemographic variables, medical history, previous pulmonary evaluation, and respiratory complications were recorded. A two-year follow-up was carried out.

Results

A total of 160 patients were included. 74.4% of the patients were men, and the mean age was 72 years. 69.4% had a smoking habit, and 41.2% consumed alcohol. Comorbidities were documented in 82.5% of patients, with hypertension being the most prevalent, while COPD ranked fifth at 8.1%. Prior to surgery, only 16% of patients underwent spirometry, and fewer than 2% were evaluated in the pulmonology clinic.
Ten patients (6.25%) developed respiratory complications. Of these, 80% were smokers, and 30% had COPD, yet none had been evaluated in the pulmonology clinic prior to surgery. Diabetes mellitus and non-epidermoid cancer types were significantly associated with complications (P < .05).

Conclusions

6.25% of patients who underwent surgery for HNC experienced respiratory complications. Although this rate is lower than those reported in other studies, it is noteworthy. This is especially relevant considering that, despite 30% of these patients having a prior diagnosis of COPD, none were evaluated before surgery to optimize treatment for this condition. These findings underscore the importance of identifying and managing COPD in patients with HNC and the need for further research in this area.
背景与目的头颈癌(HNC)的发病率与烟酒消费直接相关,这就解释了为什么HNC患者经常出现合并症,慢性阻塞性肺疾病(COPD)就是一个例子。这种情况没有得到充分的诊断,许多作者已经证明了它的存在如何增加了接受HNC手术的患者呼吸系统并发症的发生率。我们进行了一项研究,旨在评估在圣佩德罗大学医院(HUSP)接受HNC手术的患者的呼吸并发症。材料和方法进行了一项回顾性和描述性研究,包括2018年至2021年期间在Logroño HUSP接受手术的所有诊断为口腔、咽喉癌或喉癌的成年患者。记录社会人口学变量、病史、既往肺部评估和呼吸系统并发症。进行了为期两年的随访。结果共纳入160例患者。男性占74.4%,平均年龄72岁。69.4%有吸烟习惯,41.2%有饮酒习惯。82.5%的患者有合并症,其中高血压最为普遍,而COPD排名第五,为8.1%。在手术前,只有16%的患者接受了肺活量测定,不到2%的患者在肺科诊所接受了评估。10例(6.25%)出现呼吸道并发症。其中,80%是吸烟者,30%患有慢性阻塞性肺病,但在手术前没有人在肺科诊所接受过评估。糖尿病和非表皮样癌类型与并发症显著相关(P <;结论6.25%的HNC手术患者出现呼吸系统并发症。虽然这一比率低于其他研究报告,但值得注意。考虑到尽管这些患者中有30%先前诊断为COPD,但在手术前没有对其进行评估以优化治疗,这一点尤为重要。这些发现强调了在HNC患者中识别和管理COPD的重要性以及在这一领域进一步研究的必要性。
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引用次数: 0
Nebulized hyaluronic acid and xylitol based solution after turbinate radiofrequency ablation. A triple blind randomized multicentric clinical trial 鼻甲射频消融后雾化透明质酸和木糖醇基溶液。一项三盲随机多中心临床试验
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-05-01 DOI: 10.1016/j.otorri.2025.512218
Christian Calvo-Henríquez , Ainhoa García-Lliberos , Byron Maldonado-Alvarado , Miguel Rodriguez-Iglesias , David Lobo-Duro , Juan Maza-Solano , Serafín Sánchez-Gomez , Isam Alobid

Objective

This prospective, triple blind randomized clinical trial aims to specifically evaluate the effect of Aluneb® (hyaluronic acid plus xilitol) in the postoperative treatment of inferior turbinate radiofrequency in adults compared to nebulized isotonic saline.

Methods

Adults undergoing radiofrequency turbinate ablation were included. Treatment group received Aluneb® (hyaluronic acid plus xylitol) while the control group received nebulized isotonic saline for two months after treatment. Participants were studied the week before surgery (visit 0), and at 7, 15, 30 and 60 days after surgery. At all visits, participants underwent physical examination, rhinomanometry, SNOT-22, and visual analogue scale (VAS) of symptoms.

Results

34 participants were recruited. Crusts (endoscopy) were less in the Aluneb® hyaluronic acid plus xylitol group. Nasal crusting, epistaxis and nasal obstruction VAS were statistically significant lower. VAS for Rhinorrea, halitosis, cacosmia and pain and nasal resistance obtained lower self-reported values in the hyaluronic acid plus xilitol group, but these differences were not statistically significant.

Conclusions

Hyaluronic acid plus xilitol demonstrated promise in improving postoperative outcomes, future studies with larger sample sizes and different surgical techniques are encouraged.
目的:本前瞻性、三盲随机临床试验旨在专门评估Aluneb®(透明质酸加西利醇)在成人下鼻甲术后射频治疗中的效果,并与雾化等渗盐水进行比较。方法选取接受射频鼻甲消融的成人为研究对象。治疗组给予Aluneb®(透明质酸加木糖醇)治疗,对照组给予等渗生理盐水雾化治疗2个月。参与者在手术前一周(第0次访问)以及手术后7、15、30和60天进行研究。在所有访问中,参与者接受体格检查、鼻测压、SNOT-22和症状视觉模拟量表(VAS)。结果共招募34名受试者。Aluneb®透明质酸加木糖醇组结痂(内窥镜检查)较少。鼻结皮、鼻出血、鼻塞VAS均有统计学意义。透明质酸加西利醇组鼻臭、口臭、鼻臭、疼痛和鼻阻力VAS自述值较低,但差异无统计学意义。结论透明质酸加西利醇可改善术后预后,值得进一步开展更大样本量和不同手术技术的研究。
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引用次数: 0
Epignatus: una causa inusual de obstrucción de vía aérea en el recién nacido Epignatus:新生儿呼吸道阻塞的一种不寻常原因
IF 0.9 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-05-01 DOI: 10.1016/j.otorri.2025.512232
Mónica Rueda Vega, Alex Lowy Benoliel, Rosalía Souvirón Encabo
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引用次数: 0
期刊
Acta otorrinolaringologica espanola
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