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Pedicled myocutaneous trapezius flap for chronic osteomyelitis of the spinous processes - a case report. 带蒂斜方肌皮瓣治疗棘突慢性骨髓炎1例。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.48095/ccachp2024124
P Vodička, V Mařík

Complex injuries to the posterior trunk can still pose a significant challenge to the reconstructive surgeon. Due to the lack of skin laxity, dependent anatomical location and the importance of the deeper structures, a systematic approach tailored to the individual defect should be considered for these types of reconstructions. In our case report, we present a reconstructive solution of a chronic defect of the back caused by resection of an ulceration. What was previously considered to be a relapse of a malignant melanoma turned out to be a chronic osteomyelitis of the spinous processes of the thoracic vertebrae. The defect after the resection of the ulceration and infected spinous processes of the thoracic vertebrae with exposed dorsal lamina was covered with pedicled myocutaneous flap. Reconstruction yielded well-vascularized tissue that provided sufficient volume and tissue quality. Even in the light of modern perforator flaps, local or locoregional muscle and myocutaneous flaps remain the first choice for the treatment of deep back defects. Considering all the factors in the given case, plastic surgeons are able to tailor the reconstructive technique to every individual case to match the desired reconstruction goal.

复杂的后干损伤仍然是重建外科医生面临的重大挑战。由于缺乏皮肤松弛,依赖解剖位置和深层结构的重要性,应该考虑针对个体缺陷的系统方法进行这些类型的重建。在我们的病例报告,我们提出了一个重建的解决方案的慢性缺陷的背部引起的切除溃疡。先前被认为是恶性黑色素瘤复发的结果是胸椎棘突的慢性骨髓炎。切除胸椎溃疡及感染棘突及暴露背椎板后的缺损,用带蒂肌皮瓣覆盖。重建得到血管化良好的组织,提供了足够的体积和组织质量。即使在现代穿支皮瓣的情况下,局部或局部肌肉和肌皮瓣仍然是治疗深部背部缺损的首选。考虑到给定病例的所有因素,整形外科医生能够为每个病例量身定制重建技术,以达到期望的重建目标。
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引用次数: 0
Systemic allopurinol administration reduces malondialdehyde, interleukin 6, tumor necrosis factor α, and increases vascular endothelial growth factor in random flap Wistar rats exposed to nicotine. 在暴露于尼古丁的随机皮瓣 Wistar 大鼠体内,全身服用别嘌醇可降低丙二醛、白细胞介素 6 和肿瘤坏死因子 α,并增加血管内皮生长因子。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.48095/ccachp202460
I Gitaswari, A R R H Hamid, I G P H Sanjaya, G W Samsarga, A A W Lestari, I W Niryana, I M Darmajaya

Introduction: Smoking poses a risk to flap viability, with nicotine being a major contributor to the formation of free radicals. Allopurinol, known for its antioxidant properties, has been shown to enhance tissue survival in ischemic conditions by reducing the production of reactive oxygen species (ROS). This study aims to assess the impact of allopurinol on the viability and success of skin flaps in Wistar rats exposed to nicotine.

Methods: This study examined skin flap survival in nicotine-exposed rats treated with allopurinol. Twenty-eight rats were separated into two groups. During 1 month of nicotine exposure, the treatment group received systemic allopurinol 7 days before and 2 days after the flap procedure, while the control group received no allopurinol. Pro-angiogenic factors, proinflammatory factors, anti-inflammatory factors, and oxidative markers were assessed on the 7th day after the flap procedure using enzyme-linked immunosorbent assay method. Macroscopic flap viability was evaluated on the 7th day using Image J photos.

Results: As an oxidative marker, malondialdehyde levels were significantly lower in rats given allopurinol than in controls (P < 0.001). The levels of interleukin 6 and tumor necrosis factor α, as markers of inflammatory factors, were significantly lower in the group of rats given allopurinol compared to controls (P < 0.001). The level of angiogenesis in rats given allopurinol, measured by vascular endothelial growth factor levels, was also higher in the treatment group compared to controls (P < 0.001). Macroscopically, the percentage of distal flap necrosis in Wistar rats given allopurinol was lower and statistically significant compared to controls (P < 0.001).

Conclusions: Xanthine oxidoreductase is part of a group of enzymes involved in reactions that produce ROS. Allopurinol, as an effective inhibitor of the xanthine oxidase enzyme, can reduce oxidative stress by decreasing the formation of ROS. This reduction in oxidative stress mitigates the risk of ischemic-reperfusion injury effects and significantly increases the viability of Wistar rat flaps exposed to nicotine.

导言:尼古丁是形成自由基的主要因素之一,吸烟会危及皮瓣的存活率。别嘌醇因其抗氧化特性而闻名,已被证明能通过减少活性氧(ROS)的产生来提高缺血条件下组织的存活率。本研究旨在评估别嘌醇对暴露于尼古丁的 Wistar 大鼠皮瓣存活率和成功率的影响:本研究对接受别嘌醇治疗的尼古丁暴露大鼠的皮瓣存活率进行了检测。28 只大鼠被分为两组。在尼古丁暴露 1 个月期间,治疗组在皮瓣手术前 7 天和手术后 2 天接受全身性别嘌呤醇治疗,而对照组则不接受别嘌呤醇治疗。在皮瓣手术后第 7 天,使用酶联免疫吸附法评估促血管生成因子、促炎因子、抗炎因子和氧化标记物。第 7 天使用 Image J 照片评估皮瓣的宏观存活率:作为氧化标记物,服用别嘌呤醇的大鼠丙二醛水平明显低于对照组(P <0.001)。白细胞介素 6 和肿瘤坏死因子 α 是炎症因子的标志物,与对照组相比,服用别嘌醇组的白细胞介素 6 和肿瘤坏死因子 α 水平明显降低(P < 0.001)。用血管内皮生长因子水平来衡量别嘌醇治疗组大鼠的血管生成水平,也高于对照组(P < 0.001)。从宏观上看,与对照组相比,服用别嘌醇的 Wistar 大鼠远端皮瓣坏死的百分比更低,且具有统计学意义(P < 0.001):黄嘌呤氧化还原酶是参与产生ROS反应的一组酶的一部分。别嘌醇作为黄嘌呤氧化酶的有效抑制剂,可以通过减少 ROS 的形成来减轻氧化应激。氧化应激的减少减轻了缺血再灌注损伤效应的风险,并显著提高了暴露于尼古丁的 Wistar 大鼠皮瓣的存活率。
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引用次数: 0
Nail bed trauma reconstruction and artificial nail replacement - a case report. 甲床创伤重建和人工甲置换--病例报告。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.48095/ccachp202422
V Woznica, I Třešková, M Soukup

Nail bed reconstruction is crucial after fingertip trauma, impacting both function and aesthetics. In this article, the authors describe a case of partial distal phalanx amputation of the index finger with laceration of the nail bed's remaining part. A traumatically elevated skin-fat flap covered the exposed bone on the fingertip, preserving finger length and sensitivity on the radial side. A full-thickness skin graft from the forearm closed a secondary defect on the finger pulp. Nail bed suturing prevented scarring and nail deformity, and a temporary artificial plastic nail replacement maintained the nail bed's shape. Temporary artificial nail replacements protect the regenerating fingertip bed, promote healing, and prevent nail deformities. Proper adaptation of lacerated nail bed edges, supported by either the patient's own nail or a temporary artificial nail, is crucial for optimal fingertip restoration, including proper nail shape.

指尖创伤后的甲床重建至关重要,对功能和美观都有影响。在这篇文章中,作者描述了一例食指远端指骨部分截肢、甲床剩余部分撕裂的病例。创伤性隆起的皮脂瓣覆盖了指尖暴露的骨头,保留了手指的长度和桡侧的灵敏度。从前臂移植的全厚皮瓣缝合了指肉上的继发性缺损。甲床缝合防止了疤痕和指甲畸形,临时人工塑料甲替代物保持了甲床的形状。临时人工甲替代物可保护再生的指尖甲床,促进愈合,防止指甲畸形。在患者自身指甲或临时人工指甲的支撑下,适当调整撕裂的甲床边缘,对于指尖的最佳修复(包括正确的指甲形状)至关重要。
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引用次数: 0
Efficacy of collagen and elastin matrix in the treatment of complex lower extremity wounds. 胶原蛋白和弹性蛋白基质在治疗复杂下肢伤口方面的疗效。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.48095/ccachp202498
K N Manjunath, V Nisarga, M S Venkatesh, P Sanmathi, S Shanthkumar

Successful engraftment of skin grafts highly depends on the quality of the wound bed. Good quality of blood vessels near the surface is critical to support the viability of the graft. Ischemic, irradiated scar tissue, bone and tendons will not have the sufficient blood supply. In such situations flaps are to be resorted. However, the flaps also need to have good vascularity over the limbs. The introduction of dermal substitutes has provided a novel method for repairing various severe skin defects. These substitutes act as dermal regenerative templates, which facilitate dermal reconstruction and regeneration. This study was done to ascertain the effectiveness of these substitutes in the treatment of complex wounds. Between January 2022 and June 2023, 20 patients who had complex wounds, which could not be treated with simple skin grafting and who were treated with collagen and elastin matrix and split skin grafting (SSG) were retrospectively studied. The percentage of SSG take as per the records was noted at a 10-day post-operative period. Patient characteristics, comorbidities, duration and outcomes of the treatment were noted. Twenty patients were included in the study. The minimum size of the ulcer was 5 × 4 cm (area of 20 cm2) and the maximum size of the ulcer was 15 × 15 cm (225 cm2). Average take of skin graft was 93.7% at 10th post-operative day. Recurrence at 6 months was nil. The scar quality was assessed by patient and observer at 3 months and 6 months post-operatively. The lower-limb ulcers with compromised surrounding tissue are complex. The major goal in these cases is to do simple surgery and prevent recurrence. The collagen and elastin matrices provide structural support for cellular infiltration, which helps maximize a SSG take and a stable long-term scar.

植皮的成功与否在很大程度上取决于伤口床的质量。近表面的良好血管质量是支持移植物存活的关键。缺血的、受辐照的疤痕组织、骨和肌腱将没有足够的血液供应。在这种情况下,只能使用襟翼。然而,皮瓣也需要在四肢上有良好的血管。真皮替代品的引入为修复各种严重皮肤缺陷提供了一种新的方法。这些替代品作为真皮再生模板,促进真皮重建和再生。这项研究是为了确定这些替代品在治疗复杂伤口中的有效性。回顾性研究了2022年1月至2023年6月间20例单纯植皮无法治疗的复杂创面,采用胶原弹性蛋白基质联合裂皮植皮(SSG)治疗的患者。在术后10天记录SSG的摄取百分比。记录患者特征、合并症、持续时间和治疗结果。20名患者被纳入研究。溃疡最小尺寸为5 × 4 cm(面积20 cm2),最大尺寸为15 × 15 cm(面积225 cm2)。术后第10天平均植皮率为93.7%。6个月无复发。术后3个月和6个月分别由患者和观察员对瘢痕质量进行评估。下肢溃疡伴周围组织受损是复杂的。这些病例的主要目标是做简单的手术,防止复发。胶原蛋白和弹性蛋白基质为细胞浸润提供结构支持,这有助于最大限度地发挥SSG的作用和稳定的长期疤痕。
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引用次数: 0
Median nerve entrapments in the forearm - a case report of rare anterior interosseous nerve syndrome. 前臂正中神经陷伤——一例罕见的骨间前神经综合征病例报告。
Q4 Medicine Pub Date : 2023-01-01 DOI: 10.48095/ccachp202370
P Vondra, M Vlach

Nowadays, median nerve entrapment is a frequent issue. Many physicians are familiar with the most common median entrapment, which is the carpal tunnel syndrome (CTS). By contrast, less frequent entrapments, historically called "pronator syndrome" are still misdiagnosed as overuse syndrome, flexor tendinitis or other conditions. This article is meant to introduce proximal median nerve entrapments, followed by a case report of the rarest example - anterior interosseous nerve syndrome (AIN syndrome).

如今,正中神经卡压是一个常见的问题。许多医生都熟悉最常见的正中神经卡压,即腕管综合征(CTS)。相比之下,历史上被称为“旋前肌综合征”的不太频繁的诱捕仍然被误诊为过度使用综合征、屈肌肌腱炎或其他疾病。本文旨在介绍正中近端神经圈套器,然后报道最罕见的病例——骨间前神经综合征(AIN综合征)。
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引用次数: 0
3D maxillofacial surgery planning - one decade development of technology. 3D 颌面外科规划--十年技术发展。
Q4 Medicine Pub Date : 2023-01-01 DOI: 10.48095/ccachp2023128
D Hrušák, L Hauer, J Genčur, A Pěnkava, Micopulos

Nowadays, techniques and the use of patient specific implants seem to be the recent high technology standard in reconstructive surgery. Surgery planning is as old as the surgery procedures themselves. Any good surgeon, before entering the operating theatre, has a plan for how to proceed. It is based on knowledge and experience in combination of evaluation of all case relevant information. In fact, virtual surgery planning and CAD/CAM reflects the technological "state of the art" into the medical daily practice. Recently, 3D printing technologies became easy and accessible for everyone. Virtual 3D images substituted the plaster models, the film profile analysis switched to digital, 3D printed bone models of the case helped to understand the morphology of the deformity and prepare the osteotomies with "hands on the bone". The authors' own 20 years of experience on surgical planning, the development of digital technologies in oral and maxillofacial surgery is traced and comments on case examples are presented.

如今,技术和病人专用植入物的使用似乎已成为整形外科的最新高科技标准。手术计划与手术过程本身一样古老。任何优秀的外科医生在进入手术室之前,都会对如何进行手术有一个计划。它基于知识和经验,结合对所有病例相关信息的评估。事实上,虚拟手术规划和 CAD/CAM 反映了医疗日常实践中的技术 "现状"。最近,3D 打印技术变得简单易行,人人都能使用。虚拟三维图像取代了石膏模型,胶片轮廓分析转为数字化,三维打印的病例骨模型有助于了解畸形的形态,并 "手把手 "地为截骨做准备。作者回顾了自己 20 年的手术规划经验、口腔颌面外科数字化技术的发展,并对病例进行了点评。
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引用次数: 0
Scalp arteriovenous malformations - 20 years of experience in a tertiary healthcare centre. 头皮动静脉畸形--一家三级医疗中心的 20 年经验。
Q4 Medicine Pub Date : 2023-01-01 DOI: 10.48095/ccachp2023106
R I Pongeluppi, R A Monteiro Cardoso, E L Zucoloto Jr, M F M Ballestero, R Santos De Oliveira, D G Abud, J A Farina Jr, B O Colli

Background: Scalp arteriovenous malformations (SAVM) are extremely uncommon vascular malformations, with only ~200 cases published in the English language in the past years. The objective of the present study was to describe the experience of a single reference service in neurosurgery.

Methods: This is a descriptive and retrospective study conducted at our institution, which included cases of SAVM treated between 2001 and 2022. All information were extracted from the medical records of our institution. Patient confidentiality was preserved. Furthermore, an illustrative case has been described in detail.

Results: Seven patients were included. The male-to-female ratio was 2.5: 1 and the mean age was 23.3 (3-42) years. Most cases (56.4%) were spontaneous and the lesions were located in the frontal (28.7%) and parietal (28.7%) regions. All lesions were supplied by more than one feeder, with the superficial temporal and occipital arteries being the most commonly involved (71.5%). Six patients underwent preoperative embolization, and 56.4% patients had scalp necrosis. Five patients underwent surgical resection, all without recurrence and with good postoperative evolution.

Conclusions: More than one artery was involved in all cases, and the properties of the involved vessel influences the approach strategy. Surgical treatment is curative, and preoperative embolization helps reduce bleeding during the surgery. Complete resection of the lesions prevents associated complications, such as bleeding or recurrence. Scalp necrosis is a frequent complication in the treatment of these lesions, and a multidisciplinary approach involving reconstructive plastic surgery should always be considered.

背景:头皮动静脉畸形(SAVM)是一种极为罕见的血管畸形,过去几年中仅有约 200 个病例以英文发表。本研究的目的是描述神经外科一个参考服务机构的经验:本研究是一项描述性和回顾性研究,在我院进行,包括 2001 年至 2022 年间接受治疗的 SAVM 病例。所有信息均来自我院的医疗记录。患者信息保密。此外,还详细描述了一个示例病例:结果:共纳入七名患者。男女比例为 2.5:1,平均年龄为 23.3 (3-42)岁。大多数病例(56.4%)为自发性,病灶位于额叶(28.7%)和顶叶(28.7%)。所有病变均由一条以上的供血动脉供血,其中颞浅动脉和枕动脉最常受累(71.5%)。六名患者在术前接受了栓塞治疗,56.4%的患者出现头皮坏死。五名患者接受了手术切除,均未复发,术后恢复良好:结论:所有病例都有一条以上的动脉受累,受累血管的特性会影响手术策略。手术治疗是治愈性的,术前栓塞有助于减少手术中的出血。彻底切除病灶可预防出血或复发等相关并发症。头皮坏死是治疗此类病变的常见并发症,因此应始终考虑采用涉及整形外科重建的多学科方法。
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引用次数: 0
Skin grafting on amputated lower limb, norepinephrine-induced ischemic limb necrosis - case report. 截肢下肢植皮,去甲肾上腺素诱发缺血性肢体坏死--病例报告。
Q4 Medicine Pub Date : 2023-01-01 DOI: 10.48095/ccachp2023150
K Efthymiou, J Kaťuchová, J Radoňak, M Kňazovický, J Iľková, D Tomašurová

Ischemic limb necrosis due to high dose of norepinephrine (NE) in a patient with septic shock is uncommon. Unfortunately, amputation of necrotic parts is the only available treatment. Reconstruction with skin autografts for defects resulting from the amputation of the lower limbs is challenging. Herein we report a case of digit necrosis in the upper and lower limbs after administration of a high dose of NE > 1 μcg/kg/min in a patient with septic shock. The source of infection that led to septic shock was not detected. Surgical amputation was performed as it was impossible to repair impaired vasculature and patients' life was endangered. Large defects were covered with skin autografts from the patient's thighs. The included figures demonstrate the extremities' appearance before, after amputation, during and after skin graft transplantation.

脓毒性休克患者因服用大剂量去甲肾上腺素(NE)而导致肢体缺血性坏死的情况并不常见。不幸的是,截肢是唯一可行的治疗方法。用皮肤自体移植来重建因下肢截肢而造成的缺损具有挑战性。在此,我们报告了一例脓毒性休克患者在服用大剂量 NE > 1 μcg/kg/min 后上肢和下肢发生指头坏死的病例。导致脓毒性休克的感染源没有找到。由于无法修复受损的血管,病人的生命受到威胁,因此进行了手术截肢。患者的大腿皮肤自体移植覆盖了大面积缺损。图中展示了截肢前、截肢后、植皮期间和植皮后的四肢外观。
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引用次数: 0
Preservation of supraclavicular nerve while harvesting supraclavicular lymph node flap. 保留锁骨上神经同时收获锁骨上淋巴结瓣。
Q4 Medicine Pub Date : 2023-01-01 DOI: 10.48095/ccachp2022121
Yildirim E C M, Chen S-H, Mousavi A S, Chen C H

Lymph node transfer has recently become one of the popular techniques for surgical treatment of lymphedema. We aimed to evaluate postoperative donor site numbness and other complications in patients who underwent supraclavicular lymph node flap transfer to treat lymphedema with preservation of the supraclavicular nerve. From 2004 to 2020, 44 cases of supraclavicular lymph node flap were reviewed retrospectively. In the donor area, sensorial evaluation was clinically done with the postoperative controls. Among them 26 had no numbness at all, 13 had short-term numbness, two had numbness for > 1 year and three had numbness for > 2 years. We suggest that careful preservation of the supraclavicular nerve branches can avoid the major complication of numbness around the clavicle.

淋巴结转移近年来已成为淋巴水肿手术治疗的热门技术之一。我们的目的是评估在保留锁骨上神经的情况下,接受锁骨上淋巴结瓣移植治疗淋巴水肿的患者术后供体部位麻木和其他并发症。回顾性分析2004 ~ 2020年收治的锁骨上淋巴结瓣44例。在供区,以术后对照进行临床感觉评价。其中26例完全没有麻木感,13例有短期麻木感,2例有持续麻木感;1岁,3岁麻木;2年。我们建议仔细保存锁骨上神经分支可以避免锁骨周围麻木的主要并发症。
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引用次数: 0
The effect of smoking and elderly age on digital replantation - a multivariate analysis. 吸烟和老年人对手指再植的影响——一项多变量分析。
Q4 Medicine Pub Date : 2023-01-01 DOI: 10.48095/ccachp202354
M Makeľ, A Sukop, P Waldauf, A Whitley, A Hora, R Kaiser

Introduction: It is often questioned whether to perform replantation or revision amputation for amputation injuries in elderly patients and smokers. According to the current indication criteria, neither old age nor smoking in the absence of other risk factors are considered to be risk factors for replantation failure. However, many microsurgeons still may make the decision not to perform digital replantation based solely on these factors.

Material and methods: In order to evaluate the influence of both factors, we provided univariate and multivariate analyses of patients who underwent replantation at our centre during a 10-year period. We divided patients in two groups according to age (< and ≥ 60 years) and smoking status.

Results: In the univariate analysis, there were no differences in immediate results between the two age groups. In the multivariate analysis, no statistical difference was found in neither long-term nor short-term results between the two age groups and between smokers and non-smokers.

Conclusion: Smoking and age should not be considered the only risk factors when deciding whether to perform digital replantation.

引言:对于老年患者和吸烟者的截肢损伤,人们经常质疑是否进行再植或翻修截肢。根据目前的适应症标准,无论是年龄大还是在没有其他危险因素的情况下吸烟,都不被认为是再植失败的危险因素。然而,许多显微外科医生仍然可能仅仅基于这些因素而决定不进行数字再植。材料和方法:为了评估这两个因素的影响,我们对在我们中心接受10年再植的患者进行了单变量和多变量分析。我们根据年龄(<;和≥60岁)和吸烟状况将患者分为两组。结果:在单变量分析中,两个年龄组之间的即时结果没有差异。在多变量分析中,两个年龄组之间以及吸烟者和非吸烟者之间的长期和短期结果均未发现统计学差异。结论:在决定是否进行指再植时,不应将吸烟和年龄作为唯一的危险因素。
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引用次数: 0
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Acta chirurgiae plasticae
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