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Ultrasound evaluation of chronic liver disease 慢性肝病的超声评估
IF 2.4 3区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-18 DOI: 10.1007/s00261-024-04568-2
Giovanna Ferraioli, Richard G. Barr

Chronic liver disease is a world-wide epidemic. Any etiology that causes inflammation in the liver will lead to chronic liver disease. Presently, the most common inciting factor worldwide is steatotic liver disease. Recent advances in ultrasound imaging provide a multiparametric ultrasound methodology of diagnosing, staging, and monitoring treatment of chronic liver disease. Elastography has become a standard of care technique for the evaluation of liver fibrosis. Quantitative ultrasound allows for determination of the degree of fatty infiltration of the liver. Portal hypertension is the most important factor in determination of liver decompensation. B-mode findings combined with Doppler, and elastography techniques provide qualitative and quantitative methods of determining clinically significant portal hypertension. A newer method using contrast enhanced ultrasound may allow for a non-invasive quantitative estimation of the portal pressures. This paper reviews the use of multiparametric ultrasound in the evaluation of chronic liver disease including conventional B-mode ultrasound, Doppler, elastography and quantitative ultrasound for estimation of liver fat. The recent guidelines are presented and advised protocols reviewed.

慢性肝病是一种世界性流行病。任何引起肝脏炎症的病因都会导致慢性肝病。目前,全球最常见的诱发因素是脂肪肝。超声成像技术的最新进展为慢性肝病的诊断、分期和治疗监测提供了一种多参数超声方法。弹性成像已成为评估肝纤维化的标准技术。定量超声波可确定肝脏脂肪浸润的程度。门静脉高压是确定肝脏失代偿的最重要因素。B 型超声波检查结果与多普勒和弹性成像技术相结合,可提供定性和定量的方法来确定临床上明显的门静脉高压。使用造影剂增强超声波的新方法可对门静脉压力进行无创定量评估。本文回顾了多参数超声波在慢性肝病评估中的应用,包括传统 B 型超声波、多普勒、弹性成像和用于估算肝脏脂肪的定量超声波。本文介绍了最新的指南,并对建议方案进行了回顾。
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引用次数: 0
Personal finance tips for the early career radiologist and beyond 职业生涯初期及以后放射科医生的个人理财技巧
IF 2.4 3区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-18 DOI: 10.1007/s00261-024-04550-y
Mark Ehrhart, Leila Nojaba, Sally Midani, Kevin Sweet, Nandan Keshav, Thomas Anderson

This paper aims to provide a summary of the basics of personal finance, specifically as it pertains to medical trainees and early career physicians. While not sufficient by itself, it may serve as a jumping off point for further reading and investigation into different aspects of personal finance. It includes discussion of spending and saving, emergency funds, insurance, student loans, and investments and tax-advantaged retirement accounts. Graduating financially well-rounded radiologists and physicians allows for a more effective balance of patient care, education, family, and interests outside of work.

本文旨在总结个人理财的基本知识,特别是与医学实习生和初入职场的医生相关的知识。虽然它本身并不充分,但可以作为进一步阅读和研究个人理财不同方面的跳板。它包括对支出和储蓄、应急基金、保险、学生贷款以及投资和税收优惠退休账户的讨论。培养出财务状况良好的放射科医生和内科医生,可以更有效地平衡病人护理、教育、家庭和工作以外的兴趣。
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引用次数: 0
Plasmacytoid urothelial carcinoma: a multidisciplinary approach to the diagnosis and management 浆液性尿路上皮癌:诊断和管理的多学科方法
IF 2.4 3区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-17 DOI: 10.1007/s00261-024-04553-9
Marcus Zorovich, Jude Khatib, Aysha Mubeen, Katie Gardner, Nayana Patel
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引用次数: 0
Intracholecystic papillary neoplasm misdiagnosed as adenomyomatosis on imaging: a case report 被误诊为腺肌瘤病的胆囊内乳头状瘤:病例报告
IF 2.4 3区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-17 DOI: 10.1007/s00261-024-04574-4
Bunta Tokuda, Osamu Sato, Kazuhiro Katada, Mizuki Honda, Tetsuya Imura, Toshiya Ochiai

Intracholecystic papillary neoplasm (ICPN) is a rare preinvasive neoplasm of the gallbladder. The lesion typically appears as a polypoid lesion or gallbladder wall thickening. We report a case involving a 40-year-old man with an ICPN that lacked typical polypoid lesions and was difficult to differentiate from adenomyomatosis because of the presence of intramural cysts. Initial contrast-enhanced computed tomography and magnetic resonance imaging showed edematous gallbladder wall thickening. The lumen was constricted and surrounded by a cluster of small cysts that were suspected to be Rokitansky–Aschoff sinuses (RAS). There were also large cysts within the gallbladder wall. No mucosal irregularities or polypoid lesions were observed, and the mucosal continuity was preserved. After antimicrobial therapy, follow-up computed tomography revealed improvement in the thickening of the gallbladder wall; however, the cysts persisted and some had enlarged. The patient underwent laparoscopic cholecystectomy. Pathologically, a tubulopapillary lesion with atypical epithelial cells was observed in the lumen of the gallbladder, extending continuously into the RAS and cysts within the gallbladder wall. High-grade dysplasia was occasionally found, and microscopic foci of invasion were present. ICPN with associated invasive carcinoma was diagnosed. In conclusion, ICPN may not exhibit polypoid lesions or significant wall thickening on imaging. ICPN may present with secondary RAS dilatation, and the presence of large intramural cysts may be helpful in the diagnosis.

胆囊内乳头状瘤(ICPN)是一种罕见的胆囊浸润前肿瘤。这种病变通常表现为息肉样病变或胆囊壁增厚。我们报告了一例 40 岁男性的 ICPN 病例,该病例缺乏典型的息肉样病变,而且由于存在壁内囊肿,很难与腺肌瘤病相鉴别。最初的造影剂增强计算机断层扫描和磁共振成像显示胆囊壁水肿增厚。胆囊管腔狭窄,周围有一簇小囊肿,疑似罗基坦斯基-阿肖夫窦(RAS)。胆囊壁内也有大囊肿。未发现粘膜不规则或息肉样病变,粘膜的连续性得以保留。在接受抗菌治疗后,随访的计算机断层扫描显示胆囊壁增厚的情况有所改善,但囊肿依然存在,部分囊肿还增大了。患者接受了腹腔镜胆囊切除术。病理检查发现,胆囊腔内有管状乳头状病变,伴有非典型上皮细胞,并不断延伸至RAS和胆囊壁内的囊肿。偶尔会发现高级别发育不良,显微镜下可见浸润灶。经诊断,ICPN伴有浸润癌。总之,ICPN 在影像学上可能不会表现出息肉样病变或明显的壁增厚。ICPN可能伴有继发性RAS扩张,出现大的壁内囊肿可能有助于诊断。
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引用次数: 0
Dispelling myths about the use of magnetic resonance imaging in the diagnosis of adnexal torsion. 揭开磁共振成像在附件扭转诊断中的神秘面纱。
IF 2.3 3区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-16 DOI: 10.1007/s00261-024-04563-7
Ali Batur, Volkan Arslan, Elif Öztürk İnce, Aslı Nur Kılınç, Ahmet Gürkan Erdemir, Esra Kutsal Mergen
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引用次数: 0
Radiological features of pancreatic desmoid-type fibromatosis: a case series and systematic review 胰腺脱模型纤维瘤病的放射学特征:病例系列和系统综述
IF 2.4 3区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-15 DOI: 10.1007/s00261-024-04570-8
Tomoya Tanishima, Ryo Kurokawa, Miyuki Sone, Yudai Nakai, Masahiko Kusumoto

Purpose

This retrospective study aimed to investigate the radiological features of pancreatic desmoid-type fibromatosis (PDF) and systematically review the previous publications and two new cases.

Methods

We searched PubMed, Cochrane Library, and Web of Science Core Collection and included 31 patients with pathologically proven PDFs with analyzable preoperative computed tomography (CT) and magnetic resonance imaging, including two patients from our institution and 29 patients from 28 publications. Two board-certified radiologists reviewed all images.

Results

The median age of the patients was 39 years, with a male dominance observed (male, 54.8% vs. female, 45.2%). Abdominal pain was the most frequent symptom, occurring in 58.1% of cases. Surgical resection was performed in all cases of PDFs, resulting in a recurrence rate of 8.3% (2/24). The tumors were most commonly located in the pancreatic tail (23/31, 74.2%). In terms of morphology, a “solid” shape was most prevalent (14/31, 45.2%), followed by a “solid and cystic” shape (9/31, 29.0%) and a “cystic” shape (8/31, 25.8%). Characteristic radiological features included heterogeneous enhancement of the solid portion of the tumors on CT scans (13/20, 65%), moderate-to-weak enhancement in the late phase on CT (16/17, 94.1%), and a presence of cystic components in the tumors (17/31, 54.8%). In 16.1% (5/31) of PDFs, the cystic component was pathologically confirmed to be a dilated pancreatic duct.

Conclusion

We summarized the clinical and imaging characteristics of PDF. Although the incidence may not be high, cystic components suggesting a dilated pancreatic duct within the tumor are unique imaging features in PDF.

方法我们检索了PubMed、Cochrane图书馆和Web of Science核心数据库,纳入了31例经病理证实、术前计算机断层扫描(CT)和磁共振成像可分析的PDF患者,其中包括本院的2例患者和28篇文献中的29例患者。结果患者的中位年龄为 39 岁,男性居多(男性占 54.8%,女性占 45.2%)。腹痛是最常见的症状,占58.1%。所有 PDF 病例均进行了手术切除,复发率为 8.3%(2/24)。肿瘤最常位于胰腺尾部(23/31,74.2%)。就形态而言,"实性 "肿瘤最常见(14/31,45.2%),其次是 "实性和囊性 "肿瘤(9/31,29.0%)和 "囊性 "肿瘤(8/31,25.8%)。特征性的放射学特征包括 CT 扫描中肿瘤实性部分的异质强化(13/20,65%)、CT 晚期的中度至弱度强化(16/17,94.1%)以及肿瘤中囊性成分的存在(17/31,54.8%)。结论我们总结了 PDF 的临床和影像学特征。我们总结了 PDF 的临床和影像学特征。虽然发病率可能不高,但囊性成分提示肿瘤内有扩张的胰管是 PDF 的独特影像学特征。
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引用次数: 0
Differentiating struma ovarii from FIGO stage I malignant ovarian tumors in O-RADS MRI 5 lesions: a targeted cohort study 在 O-RADS MRI 5 病变中区分卵巢肿和 FIGO I 期恶性卵巢肿瘤:一项有针对性的队列研究
IF 2.4 3区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-14 DOI: 10.1007/s00261-024-04564-6
Rongping Ye, Yao Zheng, Feng Pan, Huifang Wang, Chuan Yan, Yueming Li
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引用次数: 0
A case of chronic contained rupture of abdominal aortic aneurysm mimicking a retroperitoneal tumor 一例模仿腹膜后肿瘤的慢性腹主动脉瘤破裂病例
IF 2.4 3区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-14 DOI: 10.1007/s00261-024-04572-6
Shojiro Oka, Shigeshi Kohno, Yuko Someya, Atsushi Yoshida, Shigeki Arizono, Tsuyoshi Suga, Reiichi Ishikura, Daisuke Yamashita, Shigeo Hara, Kumiko Ando

Chronic contained rupture of abdominal aortic aneurysm (CCR-AAA) is a rare subtype of abdominal aortic rupture that can mimic other retroperitoneal lesions. We report a case of CCR-AAA in a man in his sixties who presented with a 10-month history of right low back pain and weight loss. Contrast-enhanced computed tomography (CT) revealed a lobulated retroperitoneal mass around the abdominal aorta, initially misdiagnosed as a possible hemorrhagic retroperitoneal tumor. Despite multiple imaging studies including CT, magnetic resonance imaging (MRI), and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET)/CT, as well as a CT-guided biopsy, the correct diagnosis remained elusive for 34 months. Key findings included subtle aortic wall irregularity on CT, high signal intensity on T1-weighted MRI suggesting hematoma, peripheral FDG uptake on PET/CT, and histological findings of biopsy tissue consistent with organizing hematoma. Surgery confirmed the diagnosis, revealing an organized hematoma with a defect in the right wall of the abdominal aortic aneurysm. This case demonstrates that CCR-AAA can present with atypical radiological features, potentially leading to misdiagnosis. When encountering a para-aortic mass with a hemorrhagic component, careful observation of the AAA morphology and aortic wall contour is crucial for an accurate diagnosis of CCR-AAA.

腹主动脉瘤慢性包含性破裂(CCR-AAA)是腹主动脉破裂的一种罕见亚型,可模拟其他腹膜后病变。我们报告了一例 CCR-AAA 病例,患者为一名 60 多岁的男性,10 个月前出现右腰痛和体重减轻。对比增强计算机断层扫描(CT)显示腹主动脉周围有一个分叶状的腹膜后肿块,最初被误诊为可能的出血性腹膜后肿瘤。尽管进行了包括CT、磁共振成像(MRI)和18F-氟脱氧葡萄糖正电子发射断层扫描(FDG-PET)/CT在内的多项影像学检查,并在CT引导下进行了活组织检查,但在长达34个月的时间里,正确的诊断仍然扑朔迷离。主要检查结果包括:CT显示主动脉壁有细微的不规则,T1加权磁共振成像显示血肿的高信号强度,PET/CT显示外周FDG摄取,活检组织的组织学结果与组织性血肿一致。手术确诊显示腹主动脉瘤右壁有组织血肿和缺损。本病例表明,CCR-AAA 可表现为非典型放射学特征,有可能导致误诊。当遇到带有出血成分的主动脉旁肿块时,仔细观察 AAA 形态和主动脉壁轮廓对于准确诊断 CCR-AAA 至关重要。
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引用次数: 0
Achieving sub-millisievert CT colonography for accurate colorectal tumor detection using smart examination protocols: a prospective self-controlled study 利用智能检查方案实现亚毫秒级 CT 结肠成像,准确检测结直肠肿瘤:一项前瞻性自我对照研究
IF 2.4 3区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-14 DOI: 10.1007/s00261-024-04557-5
Jingyi Zhang, Mengting Hu, Qiye Cheng, Shigeng Wang, Yijun Liu, Yujing Zhou, Jianying Li, Wei Wei

Purpose

To assess the feasibility of combining Auto-kVp selection technique, higher preset ASIR-V and noise index (NI) to realize individualized sub-mSv CT colonography (CTC) for accurate colorectal tumor detection and localization.

Methods

Ninety patients with suspected colorectal cancer (CRC) were prospectively enrolled to undergo standard dose CTC (SDCTC) in the prone and ultra-low dose CTC (ULDCTC) in the supine position. SDCTC used 120 kVp, preset ASIR-V of 30%, SmartmA for a NI of 13; ULDCTC used Auto-kVp selection technique with 80 or 100 kVp, preset ASIR-V of 60%, SmartmA for a NI of 13 for 80 kVp, and NI of 15 for 100 kVp. The effective dose (ED), image quality [signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of colorectal neoplasms] between the two protocols were compared and the accuracies of tumor locations were evaluated for CTC in comparison with the surgery results.

Results

The mean ED of the ULDCTC-80 kVp subgroup was 0.70 mSv, 71.43% lower than the 2.45 mSv for the 120 kVp group, while that of the ULDCTC-100 kVp subgroup was 0.98 mSv, 73.00% lower than the 3.63 mSv for the 120 kVp group (P < 0.001). The tumor SNR and CNR of the ULDCTC were higher than those of SDCTC (P < 0.05), while there was no difference in the subjective image quality between them with good inter-observer agreement (Kappa: 0.805–0.923). Both SDCTC and ULDCTC groups had high detection rate of colorectal tumors, along with good consistency in determining tumor location compared with surgery reports (Kappa: 0.718–0.989).

Conclusion

The combination of Auto-kVp selection, higher preset ASIR-V and NI achieves individualized sub-mSv CTC with good performance in detecting and locating CRC with surgery and consistent results between SDCTC and ULDCTC.

目的评估结合自动kVp选择技术、较高的预设ASIR-V和噪声指数(NI)实现个体化亚毫西弗CT结肠成像(CTC)以准确检测和定位结直肠肿瘤的可行性。方法对90例疑似结直肠癌(CRC)患者进行前瞻性入组,分别采用俯卧位标准剂量CTC(SDCTC)和仰卧位超低剂量CTC(ULDCTC)。SDCTC 使用 120 kVp,预设 ASIR-V 为 30%,SmartmA 的 NI 为 13;ULDCTC 使用 80 或 100 kVp 的自动 kVp 选择技术,预设 ASIR-V 为 60%,SmartmA 80 kVp 的 NI 为 13,100 kVp 的 NI 为 15。比较了两种方案的有效剂量(ED)、图像质量[结直肠肿瘤的信噪比(SNR)和对比信噪比(CNR)],并将 CTC 与手术结果进行比较,评估了肿瘤位置的准确性。结果 ULDCTC-80 kVp 亚组的平均 ED 为 0.70 mSv,比 120 kVp 组的 2.45 mSv 低 71.43%,而 ULDCTC-100 kVp 亚组的平均 ED 为 0.98 mSv,比 120 kVp 组的 3.63 mSv 低 73.00%(P <0.001)。ULDCTC 的肿瘤 SNR 和 CNR 均高于 SDCTC(P < 0.05),而两者的主观图像质量无差异,观察者之间的一致性良好(Kappa:0.805-0.923)。结论自动 kVp 选择、较高的预设 ASIR-V 和 NI 的组合实现了个体化的亚毫西弗 CTC,在检测和定位 CRC 与手术方面表现良好,SDCTC 和 ULDCTC 的结果一致。
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引用次数: 0
Imaging findings of gastric glomus tumors 胃粘膜瘤的影像学检查结果
IF 2.4 3区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-14 DOI: 10.1007/s00261-024-04549-5
Kumaresan Sandrasegaran, Amar Shah, Cole Thompson, Longwen Chen, Alvin Silva

Sparse literature describes the imaging findings of gastric glomus tumors (GGT), focusing on benign tumors. We are not aware of prior radiology reports on malignant GGT. The aim of the study was to determine whether it is possible to differentiate between benign and malignant GGT on CT or MR. Institutional radiology and pathology databases were queried for the diagnosis of GGT between January 2010 to December 2023. Of 22 identified subjects, five were excluded due to non-availability of preoperative CT or MR images and three due to lack of pathological confirmation in our institution. The study cohort comprised of 14 patients (males = 6) with median age of 65 years (range 31 to 79 years). Two abdominal radiologists in consensus reviewed all relevant CT and MR images. There were 10 benign and 4 malignant GGT. Benign tumors were smaller than malignant GGT (median size of 2.0 cm vs. 5.3 cm, p = 0.03), more likely to exhibit homogeneous hyperenhancement (9/10 vs. 0/4, p < 0.01), and demonstrated intramural rather than exophytic growth. There was no substantial difference in T2 signal or diffusion restriction between benign and malignant GGT. On follow up, benign GGT were essentially stable in size, while malignant GGT grew. A biopsy proven GGT larger than 5 cm or showing necrosis is likely to be malignant. This is important since preoperative endoscopic ultrasound-guided fine needle aspiration may be indeterminate for malignancy.

描述胃胶膜瘤 (GGT) 影像学发现的文献很少,主要集中在良性肿瘤方面。我们尚未发现有关恶性 GGT 的放射学报告。本研究旨在确定是否可以通过 CT 或 MR 来区分良性和恶性 GGT。我们在机构放射学和病理学数据库中查询了 2010 年 1 月至 2023 年 12 月期间的 GGT 诊断。在确定的 22 例受试者中,有 5 例因无法获得术前 CT 或 MR 图像而被排除,3 例因本院缺乏病理证实而被排除。研究队列包括 14 名患者(男性 = 6),中位年龄为 65 岁(31 至 79 岁)。两名腹部放射科医生在协商一致的基础上审查了所有相关的 CT 和 MR 图像。其中良性 GGT 10 例,恶性 4 例。良性肿瘤比恶性 GGT 小(中位尺寸为 2.0 厘米 vs. 5.3 厘米,p = 0.03),更有可能表现出均质高增强(9/10 vs. 0/4,p <0.01),并且表现为瘤内生长而非瘤外生长。良性 GGT 和恶性 GGT 在 T2 信号或弥散受限方面没有本质区别。在随访中,良性 GGT 的大小基本稳定,而恶性 GGT 则有所增大。活组织检查证实大于 5 厘米或出现坏死的 GGT 很可能是恶性的。这一点很重要,因为术前内镜超声引导下的细针穿刺可能无法确定是否为恶性。
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引用次数: 0
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Abdominal Radiology
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