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The utility of ultrafast MRI and conventional DCE-MRI for predicting histologic aggressiveness in patients with breast cancer. 超快磁共振成像和传统 DCE-MRI 对预测乳腺癌患者组织学侵袭性的实用性。
IF 1.3 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-18 DOI: 10.1177/02841851241276422
Seong Gwang Kim,Ah Young Park,Hae Kyoung Jung,Kyung Hee Ko,Yunju Kim
BACKGROUNDPrediction of histologic prognostic markers is important for determining management strategy and predicting prognosis.PURPOSETo identify important features of ultrafast and conventional dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) that can predict histopathologic prognostic markers in patients with breast cancer.MATERIAL AND METHODSPreoperative MRI scans of 158 consecutive women (mean age = 54.0 years; age range = 29-86 years) with 163 breast cancers between February 2021 and August 2022 were retrospectively reviewed. Inter-observer agreements for ultrafast MRI parameters were analyzed by two radiologists. The qualitative and quantitative MRI parameters were correlated with histopathologic prognostic markers including molecular subtypes and histologic invasiveness.RESULTSInter-observer agreements for ultrafast MRI parameters were excellent (intraclass correlation coefficients of area under the kinetic curve [AUC], maximum slope [MS], maximum enhancement [ME], and slope = 0.987, 0.844, 0.822, and 0.760, respectively). Triple-negative breast cancers (TNBC) were significantly associated with rim enhancement (odds ratio [OR] = 9.4, P = 0.003) and peritumoral edema (OR = 17.9, P = 0.002), compared to luminal cancers. Invasive cancers were associated with lesion type-mass, increased delayed washout, angiovolume, ME, slope, MS, and AUC, compared to in situ cancers. In regression analysis, the combination of MS (>46.2%/s) (OR = 5.7, P = 0.046) and delayed washout (>17.5%) (OR = 17.6, P = 0.01), and that of AUC (>27,410.3) (OR = 9.6, P = 0.04), delayed washout (>17.5%) (OR = 8.9, P = 0.009), and lesion-type mass (OR = 4.6, P = 0.04) were predictive of histologic invasiveness.CONCLUSIONConventional DCE-MRI with ultrafast imaging can provide useful information for predicting histologic underestimation and aggressive molecular subtype. MS and AUC on ultrafast MRI can be potential imaging markers for predicting histologic upgrade from DCIS to invasive cancer with high reliability.
目的确定超快速和传统动态对比增强磁共振成像(DCE-MRI)中可预测乳腺癌患者组织病理学预后标志物的重要特征。材料与方法对 2021 年 2 月至 2022 年 8 月间连续 158 名女性(平均年龄 = 54.0 岁;年龄范围 = 29-86 岁)163 例乳腺癌患者的术前 MRI 扫描进行了回顾性审查。两名放射科医生对超快磁共振成像参数的观察者间一致性进行了分析。结果超快磁共振成像参数的观察者间一致性极佳(动力学曲线下面积[AUC]、最大斜率[MS]、最大增强[ME]和斜率的类内相关系数分别为0.987、0.844、0.822和0.760)。与管腔癌相比,三阴性乳腺癌(TNBC)与边缘强化(几率比 [OR] = 9.4,P = 0.003)和瘤周水肿(OR = 17.9,P = 0.002)显著相关。与原位癌相比,浸润癌与病变类型-质量、延迟冲洗增加、血管体积、ME、斜率、MS 和 AUC 相关。在回归分析中,MS(>46.2%/s)(OR = 5.7,P = 0.046)和延迟冲洗(>17.5%)(OR = 17.6,P = 0.01)的组合,以及AUC(>27,410.3)(OR = 9.6,P = 0.04)、延迟冲洗(>17.5%)(OR = 8.9,P = 0.009)和病变类型肿块(OR = 4.6,P = 0.04)可预测组织学侵袭性。结论常规DCE-MRI与超快速成像可为预测组织学低估和侵袭性分子亚型提供有用信息。超快磁共振成像上的 MS 和 AUC 可作为潜在的成像标记,预测组织学上从 DCIS 升级为浸润性癌症,可靠性高。
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引用次数: 0
Acetabular morphology variations in a Hispanic population. 西班牙裔人群的髋臼形态变化。
IF 1.3 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-18 DOI: 10.1177/02841851241278337
Norberto J Torres-Lugo,Danny Mangual-Perez,David Deliz-Jimenez,Andrea Lopez-Alonso,Jose Guzman-Gutierrez,Alexandra Claudio-Marcano,Edgar Colon-Negron,Ariel Davila-Parrilla
BACKGROUNDRotational abnormalities of the hip have been implicated in the etiology of diseases, such as hip dysplasia, osteoarthritis, and femoroacetabular impingement. Despite the extensive literature on hip morphology, there is a gap in knowledge regarding variations in the Hispanic population.PURPOSETo describe the bony anatomy variations of the acetabulum in a Hispanic population.MATERIAL AND METHODSThis is a cross-sectional study. We studied 182 computed tomography (CT) images in patients aged older than 21 years, who had undergone pelvic CT for any condition, except hip fracture. Measurements of acetabular version, anterior and posterior acetabular sector angles (AASA/PASA) and horizontal acetabular sector angles (HASA) were made. Acetabular variations were then compared to weight and sex data.RESULTSThe mean acetabular anteversion was greater in women (P < 0.001). Women exhibited a greater PASA (P < 0.05); however, men had a greater AASA (P < 0.05). Underweight individuals had a smaller PASA (P < 0.01) and HASA (P < 0.05) than individuals with a normal weight.CONCLUSIONThe Hispanic hip is morphologically similar to other populations previously reported in the literature; however, Hispanic men have less coverage of the femoral head by the posterior acetabular wall when compared to women of the same ethnicity. These abnormalities have a direct impact on management and surgical approach in patients treated for femoroacetabular impingement and hip dysplasia.
背景髋关节旋转异常与髋关节发育不良、骨关节炎和股骨髋臼撞击等疾病的病因有关。尽管有关髋关节形态学的文献很多,但有关西班牙裔人群髋关节形态变化的知识还是空白。我们研究了 182 张计算机断层扫描(CT)图像,研究对象是 21 岁以上、因任何疾病(髋部骨折除外)接受骨盆 CT 检查的患者。我们测量了髋臼形态、髋臼前后扇形角(AASA/PASA)和髋臼水平扇形角(HASA)。结果女性的平均髋臼前倾角更大(P < 0.001)。女性的 PASA 更大(P < 0.05);但男性的 AASA 更大(P < 0.05)。与体重正常的人相比,体重不足的人的 PASA(P < 0.01)和 HASA(P < 0.05)更小。结论:西班牙裔髋关节在形态上与之前文献报道的其他人群相似;但是,与同种族的女性相比,西班牙裔男性的股骨头较少被髋臼后壁覆盖。这些异常直接影响到股骨髋臼撞击症和髋关节发育不良患者的治疗和手术方法。
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引用次数: 0
Comparison of different radiographic methods to measure the slip angle in children with slipped capital femoral epiphysis (SCFE). 比较测量股骨头骺滑脱(SCFE)儿童滑脱角的不同放射学方法。
IF 1.1 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-01 Epub Date: 2024-08-30 DOI: 10.1177/02841851241271999
Mikael Lindell, Jens Nilsson, Bengt Herngren, Jakob Örtegren, Margaretha Stenmarker, Carl Johan Tiderius, Piotr Michno

Background: The management of patients with slipped capital femoral epiphysis (SCFE) requires imaging diagnostics of good quality and accurate measurement of the degree of slippage. In Sweden, three different radiological methods are commonly used: the calcar femorale method; the Billing method; and the Head-shaft angle described by Southwick.

Purpose: To evaluate whether any of the three most common methods used in Sweden to measure the slip angle was more useful and reproducible than the others.

Material and methods: Two experienced orthopaedists measured the slip angle in preoperative hip radiographs. Intra- and inter-observer variability between the two experienced observers and the reported value by clinicians who treated the child with SCFE was evaluated.

Results: The intraclass correlation coefficient (ICC) confidence interval (CI) between the two experienced observers and the reporting clinicians overlapped for the three methods. In 37% of the cases, the difference was more than 5° between the experienced observers' measurement and the reported value by clinicians. The two experienced orthopaedists' intra- and inter-observer variability was low.

Conclusion: The observer's experience is more important than the method of choice when measuring the slip angle in SCFE. The research group recommends the calcar femorale method due to its feasibility on the versatile and commonly used frog leg lateral view.

背景:股骨头骺滑脱(SCFE)患者的治疗需要高质量的影像诊断和对滑脱程度的精确测量。在瑞典,通常使用三种不同的放射学方法:股骨小腿法、Billing法和Southwick描述的头轴角法。目的:评估在瑞典最常用的三种测量滑脱角的方法中,是否有哪一种比其他方法更有用、更具有可重复性:材料: 两名经验丰富的骨科医生测量术前髋关节X光片上的滑移角。评估了两位经验丰富的观察者之间以及治疗 SCFE 患儿的临床医生报告值之间的观察者内部和观察者之间的变异性:结果:在三种方法中,两名经验丰富的观察者与报告的临床医生之间的类内相关系数(ICC)置信区间(CI)是重叠的。在 37% 的病例中,经验丰富的观察者的测量值与临床医生的报告值相差超过 5°。两名经验丰富的骨科医生的观察者内部和观察者之间的差异较小:结论:在测量 SCFE 滑移角时,观察者的经验比选择的方法更重要。研究小组推荐使用股骨小腿法,因为该方法在多用途和常用的蛙腿侧视图上具有可行性。
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引用次数: 0
A systematic review of deep learning-based spinal bone lesion detection in medical images. 基于深度学习的医学图像脊柱骨病变检测系统综述
IF 1.1 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-01 Epub Date: 2024-07-21 DOI: 10.1177/02841851241263066
Bianca Teodorescu, Leonard Gilberg, Philip William Melton, Rudolph Matthias Hehr, Hamza Eren Guzel, Ali Murat Koc, Andre Baumgart, Leander Maerkisch, Elmer Jeto Gomes Ataide

Spinal bone lesions encompass a wide array of pathologies, spanning from benign abnormalities to aggressive malignancies, such as diffusely localized metastases. Early detection and accurate differentiation of the underlying diseases is crucial for every patient's clinical treatment and outcome, with radiological imaging being a core element in the diagnostic pathway. Across numerous pathologies and imaging techniques, deep learning (DL) models are progressively considered a valuable resource in the clinical setting. This review describes not only the diagnostic performance of these models and the differing approaches in the field of spinal bone malignancy recognition, but also the lack of standardized methodology and reporting that we believe is currently hampering this newly founded area of research. In line with their established and reliable role in lesion detection, this publication focuses on both computed tomography and magnetic resonance imaging, as well as various derivative modalities (i.e. SPECT). After conducting a systematic literature search and subsequent analysis for applicability and quality using a modified QUADAS-2 scoring system, we confirmed that most of the 14 identified studies were plagued by major limitations, such as insufficient reporting of model statistics and data acquisition, a lacking external validation dataset, and potentially biased annotation. Although we experienced these limitations, we nonetheless conclude that the potential of these methods shines through in the presented results. These findings underline the need for more stringent quality controls in DL studies, as well as model development to afford increased insight and progress in this promising novel field.

脊柱骨病变包括一系列病理变化,从良性异常到侵袭性恶性肿瘤,如弥漫性局部转移。早期检测和准确区分潜在疾病对每位患者的临床治疗和预后至关重要,而放射成像是诊断路径中的核心要素。在众多病理和成像技术中,深度学习(DL)模型逐渐被认为是临床环境中的宝贵资源。这篇综述不仅介绍了这些模型的诊断性能和脊柱骨恶性肿瘤识别领域的不同方法,而且还介绍了标准化方法和报告的缺乏,我们认为这目前阻碍了这一新成立的研究领域。鉴于计算机断层扫描和磁共振成像在病变检测中的可靠作用,本出版物将重点关注这两种成像技术以及各种衍生模式(如 SPECT)。在进行了系统的文献检索并使用修改后的 QUADAS-2 评分系统对适用性和质量进行分析后,我们确认 14 项已确定的研究中的大多数都存在重大局限性,如模型统计和数据采集报告不充分、缺乏外部验证数据集以及注释可能存在偏差等。尽管我们遇到了这些限制,但我们还是得出结论,这些方法的潜力在所提交的结果中得到了充分体现。这些发现强调了在 DL 研究中进行更严格的质量控制以及开发模型的必要性,以便在这一前景广阔的新领域中提高洞察力并取得进展。
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引用次数: 0
The predominant insertion of the ischiofemoral ligament is a merging to the iliofemoral ligament as demonstrated on magnetic resonance arthrogram studies. 磁共振关节造影研究表明,股骨峡韧带的主要插入部位是与髂股韧带的合并处。
IF 1.1 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-01 Epub Date: 2024-07-23 DOI: 10.1177/02841851241263584
Munif Hatem, Megan Badejo, Michael McCarroll, Richard Feng, Hal David Martin

Background: The capsular ligaments at the hip joint work in synchrony with the acetabulum and femoral head for articular stability. There is a lack of understanding about ischiofemoral ligament (ISFL) anatomy and function.

Purpose: To assess the insertion of the ISFL in non-arthritic adult hips.

Material and methods: A retrospective analysis was performed in 72 patients who underwent magnetic resonance arthrogram (MRA) for the assessment of hip pain. The distribution of the ISFL components, the thickness, and the insertion site were assessed by concomitantly using the axial oblique, coronal, and sagittal MRA images.

Results: Two insertions of the ISFL anterior to the center of the femoral head were identified in 71 (99%) hips: (i) predominant anterior merging with the iliofemoral ligament as continuation of zona orbicularis, observed in all hips; and (ii) anterolateral junction of femoral neck and greater trochanter. Two ISFL parts (proximal and distal) were identified in 70 (97%) of the 72 studied hips. The proximal part was always thinner (mean 2.6 ± 0.7 mm) and originated from the ischium at the acetabular rim. The distal part was a continuation of the zona orbicularis, and the mean thickness was 6.7 ± 1.6 mm. Both parts merged as they coursed over the superior portion of the femoral head.

Conclusion: The predominant insertion of the ischiofemoral ligament is a merging to the iliofemoral ligament anteriorly. Surgical procedures such as hip arthroscopy involving the ISFL will affect the function of the iliofemoral ligament, and vice versa.

背景:髋关节的关节囊韧带与髋臼和股骨头同步工作,以保证关节的稳定性。目的:评估非关节炎成人髋关节中 ISFL 的插入情况:对72名接受磁共振关节造影(MRA)评估髋关节疼痛的患者进行了回顾性分析。同时使用轴向斜位、冠状位和矢状位 MRA 图像评估了 ISFL 成分的分布、厚度和插入部位:在71个(99%)髋关节中发现了股骨头中心前方的两个ISFL插入点:(i) 主要在前方与髂股韧带合并,作为眼轮匝肌带的延续,在所有髋关节中均可观察到;(ii) 股骨颈和大转子的前外侧交界处。在研究的 72 个髋关节中,有 70 个(97%)发现了 ISFL 的两个部分(近端和远端)。近端部分总是较薄(平均 2.6 ± 0.7 毫米),源自髋臼边缘的楔骨。远端部分是眼轮匝肌的延续,平均厚度为 6.7 ± 1.6 毫米。两部分在经过股骨头上部时合并:结论:股骨峡韧带的主要插入部位是在前方与髂股韧带合并。涉及ISFL的髋关节镜等外科手术会影响髂股韧带的功能,反之亦然。
{"title":"The predominant insertion of the ischiofemoral ligament is a merging to the iliofemoral ligament as demonstrated on magnetic resonance arthrogram studies.","authors":"Munif Hatem, Megan Badejo, Michael McCarroll, Richard Feng, Hal David Martin","doi":"10.1177/02841851241263584","DOIUrl":"10.1177/02841851241263584","url":null,"abstract":"<p><strong>Background: </strong>The capsular ligaments at the hip joint work in synchrony with the acetabulum and femoral head for articular stability. There is a lack of understanding about ischiofemoral ligament (ISFL) anatomy and function.</p><p><strong>Purpose: </strong>To assess the insertion of the ISFL in non-arthritic adult hips.</p><p><strong>Material and methods: </strong>A retrospective analysis was performed in 72 patients who underwent magnetic resonance arthrogram (MRA) for the assessment of hip pain. The distribution of the ISFL components, the thickness, and the insertion site were assessed by concomitantly using the axial oblique, coronal, and sagittal MRA images.</p><p><strong>Results: </strong>Two insertions of the ISFL anterior to the center of the femoral head were identified in 71 (99%) hips: (i) predominant anterior merging with the iliofemoral ligament as continuation of zona orbicularis, observed in all hips; and (ii) anterolateral junction of femoral neck and greater trochanter. Two ISFL parts (proximal and distal) were identified in 70 (97%) of the 72 studied hips. The proximal part was always thinner (mean 2.6 ± 0.7 mm) and originated from the ischium at the acetabular rim. The distal part was a continuation of the zona orbicularis, and the mean thickness was 6.7 ± 1.6 mm. Both parts merged as they coursed over the superior portion of the femoral head.</p><p><strong>Conclusion: </strong>The predominant insertion of the ischiofemoral ligament is a merging to the iliofemoral ligament anteriorly. Surgical procedures such as hip arthroscopy involving the ISFL will affect the function of the iliofemoral ligament, and vice versa.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1080-1086"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141750833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiplanar reconstructions of the thoracic spine in a photon counting dual-source CT scanner: comparison to EID-CT. 光子计数双源 CT 扫描仪的胸椎多平面重建:与 EID-CT 的比较。
IF 1.1 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-01 Epub Date: 2024-08-21 DOI: 10.1177/02841851241271109
Stefanie J Bette, Franziska M Braun, Jan H Luitjens, David Kaufmann, Josua Decker, Judith Becker, Christian Scheurig-Muenkler, Thomas J Kroencke, Florian Schwarz

Background: Photon-counting detector computed tomography (PCD-CT) is a groundbreaking technology with promising results for visualization of small bone structures.

Purpose: To analyze the delineation of the thoracic spine in multiplanar reconstructions (MPR) on PCD-CT compared to energy-integrating detector (EID)-CT.

Material and methods: Two euthanized mice were examined using different scanners: (i) 20-slice EID-CT and (ii) dual-source PCD-CT at various CTDIVol values. Readers evaluated the thoracic spine and selected series with best visualization among signal-to-noise ratio (SNR)-matched pairs.

Results: SNR was significantly higher in PCD-CT reconstructions (Br68) and lower in Hr98 reconstructions compared to EID-CT. Bone detail visualization was superior in PCD-CT (especially in Hr98 reconstructions) compared to EID-CT.

Conclusion: MPR on a PCD-CT had a higher SNR and better bone detail visualization even at lower radiation doses compared to EID-CT. PCD-CT with bone reconstructions showed the best delineation of small bone structures and might be considered in clinical routine.

背景:光子计数探测器计算机断层扫描(PCD-CT目的:与能量积分探测器(EID)-CT 相比,分析 PCD-CT 多平面重建(MPR)中胸椎的轮廓:使用不同的扫描仪对两只安乐死小鼠进行检查:(i) 20 片 EID-CT 和 (ii) 不同 CTDIVol 值的双源 PCD-CT。阅读者对胸椎进行评估,并在信噪比(SNR)匹配的扫描对中选择可视化效果最好的扫描序列:结果:与 EID-CT 相比,PCD-CT 重建(Br68)的信噪比明显较高,而 Hr98 重建的信噪比较低。与 EID-CT 相比,PCD-CT(尤其是 Hr98 重建)的骨细节可视化效果更好:结论:与 EID-CT 相比,PCD-CT 上的 MPR 具有更高的信噪比(SNR)和更好的骨骼细节显示,即使辐射剂量较低。PCD-CT的骨重建显示了对小骨结构的最佳描述,可在临床常规中加以考虑。
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引用次数: 0
Tract embolization with gelatin sponge after percutaneous transhepatic portal vein intervention. 经皮经肝门静脉介入术后使用明胶海绵进行栓塞。
IF 1.1 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-01 Epub Date: 2024-08-28 DOI: 10.1177/02841851241273938
Eisuke Shibata, Hidemasa Takao, Osamu Abe

Background: Bleeding from the puncture tract after percutaneous transhepatic portal vein intervention can become life-threatening. To date, studies about tract embolization with gelatin sponge after percutaneous transhepatic portal vein intervention are only with small numbers of patients, or non-consecutive or pediatric patients with a relatively small sheath in diameter.

Purpose: To evaluate the safety and efficacy of tract embolization with gelatin sponge strips after percutaneous transhepatic poral vein access.

Material and methods: Between September 2017 and February 2024, 100 consecutive patients (61 men, 39 women; mean age = 53 ± 15 years) underwent a total of 105 portal vein interventions using a percutaneous transhepatic approach. Tract embolization for the removal of 6-8 Fr sheath was performed using gelatin sponge strips in all procedures, including 71 portal vein embolization before major hepatectomy, 27 portal balloon venoplasty or stent placement after liver transplantation, and seven other interventions.

Results: No bleeding occurred after tract embolization with gelatin sponge strips. Minor portal vein thrombosis was detected in three procedures after liver transplantation and in one procedure for portal vein stenosis caused by essential thrombocytopenia. Thrombosis occurred in the punctured portal vein branch in all procedures. Thrombosis was not clinically relevant in any patient, and it was difficult to differentiate whether thrombosis was caused by sheath placement or the inserted gelatin sponge.

Conclusion: Tract embolization with gelatin sponge strips after percutaneous transhepatic portal vein intervention is a safe and feasible method for preventing hemorrhage from the puncture tract.

背景:经皮经肝门静脉介入术后穿刺道出血可能危及生命。迄今为止,有关经皮经肝门静脉介入术后使用明胶海绵条进行穿刺道栓塞的研究仅针对少数患者,或非连续性患者,或鞘管直径相对较小的儿科患者。目的:评估经皮经肝门静脉入路后使用明胶海绵条进行穿刺道栓塞的安全性和有效性。材料和方法:2017 年 9 月至 2024 年 2 月间,连续性患者 100 例(61 名男性,39 名女性;鞘管直径相对较小的儿科患者):2017年9月至2024年2月期间,100名连续患者(61名男性,39名女性;平均年龄=53±15岁)使用经皮经肝方法接受了共计105次门静脉介入治疗。所有手术均使用明胶海绵条进行门静脉栓塞以切除 6-8 Fr 的鞘管,其中包括 71 例肝大部切除术前的门静脉栓塞、27 例肝移植后的门静脉球囊静脉成形术或支架置入术以及 7 例其他介入手术:结果:使用明胶海绵条进行门静脉栓塞术后未发生出血。3例肝移植术后手术和1例因血小板减少引起的门静脉狭窄手术中发现轻微的门静脉血栓形成。在所有手术中,血栓都发生在穿刺的门静脉分支。所有患者的血栓形成都与临床无关,而且很难区分血栓形成是由鞘管置入还是明胶海绵插入造成的:结论:经皮经肝门静脉介入术后使用明胶海绵条进行穿刺道栓塞是一种安全可行的预防穿刺道出血的方法。
{"title":"Tract embolization with gelatin sponge after percutaneous transhepatic portal vein intervention.","authors":"Eisuke Shibata, Hidemasa Takao, Osamu Abe","doi":"10.1177/02841851241273938","DOIUrl":"10.1177/02841851241273938","url":null,"abstract":"<p><strong>Background: </strong>Bleeding from the puncture tract after percutaneous transhepatic portal vein intervention can become life-threatening. To date, studies about tract embolization with gelatin sponge after percutaneous transhepatic portal vein intervention are only with small numbers of patients, or non-consecutive or pediatric patients with a relatively small sheath in diameter.</p><p><strong>Purpose: </strong>To evaluate the safety and efficacy of tract embolization with gelatin sponge strips after percutaneous transhepatic poral vein access.</p><p><strong>Material and methods: </strong>Between September 2017 and February 2024, 100 consecutive patients (61 men, 39 women; mean age = 53 ± 15 years) underwent a total of 105 portal vein interventions using a percutaneous transhepatic approach. Tract embolization for the removal of 6-8 Fr sheath was performed using gelatin sponge strips in all procedures, including 71 portal vein embolization before major hepatectomy, 27 portal balloon venoplasty or stent placement after liver transplantation, and seven other interventions.</p><p><strong>Results: </strong>No bleeding occurred after tract embolization with gelatin sponge strips. Minor portal vein thrombosis was detected in three procedures after liver transplantation and in one procedure for portal vein stenosis caused by essential thrombocytopenia. Thrombosis occurred in the punctured portal vein branch in all procedures. Thrombosis was not clinically relevant in any patient, and it was difficult to differentiate whether thrombosis was caused by sheath placement or the inserted gelatin sponge.</p><p><strong>Conclusion: </strong>Tract embolization with gelatin sponge strips after percutaneous transhepatic portal vein intervention is a safe and feasible method for preventing hemorrhage from the puncture tract.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1046-1051"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142085828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The value of amide proton transfer imaging combined with serum CA125 levels in predicting lymph vascular invasion in cervical cancer before surgery. 酰胺质子转移成像结合血清 CA125 水平在手术前预测宫颈癌淋巴管侵犯中的价值。
IF 1.1 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-01 Epub Date: 2024-08-28 DOI: 10.1177/02841851241273939
Chen Xu, Xiao-Yan Zhang, Xing-Chen Wu, Lei Ming, Qian-Qian Qu, Kai Deng

Background: Preoperative prediction of lymphovascular space invasion (LVSI) is crucial for improving the prognosis of patients with cervical cancer.

Purpose: To evaluate the value of preoperative amide proton transfer (APT) imaging combined with serum CA125 levels for predicting LVSI in cervical cancer.

Material and methods: This retrospective study included 80 patients with cervical cancer who underwent preoperative magnetic resonance imaging, including APT imaging. Serum CA125 levels were measured using a fully automated immunoassay analyzer and chemiluminescence method. The presence of LVSI was determined based on the pathological results after surgery.

Results: Among the 40 patients who met the requirements, 29 had postoperative pathological confirmation of LVSI, while 11 did not. The areas under the receiver operating characteristic curves (AUC) of preoperative APT and CA125 levels predicting LVSI were 0.889 and 0.687, respectively. When the APT value was 2.9%, the corresponding Youden index was the highest (0.702), with a sensitivity of 79.3% and specificity of 90.9%. When the critical value of the preoperative serum CA15 level was 25.3 u/mL, the corresponding Youden index was the highest (0.508), with a sensitivity of 69.0% and a specificity of 81.8%. The sensitivity and specificity of preoperative APT imaging combined with serum CA125 in predicting LVSI were 82.7% and 100%, respectively, with a Youden's index of 0.828 and an AUC of 0.923.

Conclusion: The combination of preoperative APT imaging and serum CA125 levels is valuable for predicting LVSI in cervical cancer. Diagnostic efficacy is highest when the APT value is >2.9% and the serum CA125 level is >25.3 u/mL.

背景:目的:评估术前酰胺质子转移(APT)成像结合血清CA125水平预测宫颈癌淋巴管间隙侵犯(LVSI)的价值:这项回顾性研究纳入了80例接受术前磁共振成像(包括APT成像)的宫颈癌患者。使用全自动免疫测定分析仪和化学发光法测定血清 CA125 水平。根据术后病理结果确定是否存在 LVSI:在符合要求的 40 例患者中,29 例术后病理证实为 LVSI,11 例未证实。术前 APT 和 CA125 水平预测 LVSI 的接收器操作特征曲线下面积(AUC)分别为 0.889 和 0.687。当 APT 值为 2.9% 时,相应的 Youden 指数最高(0.702),敏感性为 79.3%,特异性为 90.9%。当术前血清 CA15 水平的临界值为 25.3 u/mL 时,相应的尤登指数最高(0.508),敏感性为 69.0%,特异性为 81.8%。术前 APT 成像结合血清 CA125 预测 LVSI 的敏感性和特异性分别为 82.7% 和 100%,尤登指数为 0.828,AUC 为 0.923:结论:术前APT成像与血清CA125水平相结合对预测宫颈癌LVSI很有价值。当 APT 值大于 2.9% 且血清 CA125 水平大于 25.3 u/mL 时,诊断效果最高。
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引用次数: 0
Virtual non-contrast images in photon-counting computed tomography: impact of different contrast phases. 光子计数计算机断层扫描中的虚拟非对比图像:不同对比阶段的影响。
IF 1.1 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-01 Epub Date: 2024-08-14 DOI: 10.1177/02841851241271202
Eva Laurin Gadsbøll, Marie-Louise Aurumskjöld, Fredrik Holmquist, Erik Baubeta

Background: Photon-counting computed tomography (PCCT) enables new ways of image reconstruction, e.g. material decomposition and creation of virtual non-contrast (VNC) series with higher resolution and lower radiation dose than standard computed tomography (CT). Clinical experiences of this are limited.

Purpose: To compare true non-contrast (TNC) series with VNC series derived from non-enhanced (VNCu), arterial phase (VNCa) and portal venous phase (VNCv) in clinically approved PCCT.

Material and methods: A total of 45 clinical, tri-phasic abdominal CT scans from the PCCT Naetom Alpha, between February 2022 and November 2022, were retrospectively assessed. Placing a region of interest in six different locations in each VNC series - right liver parenchyma, left liver parenchyma, spleen, aorta, erector spinae muscle, and in the subcutaneous fat - absolute Hounsfield values (HU) and standard deviations (SD) were collected. Differences in HU (ΔHU) were compared and statistically analyzed.

Results: Statistically significant differences between VNC and TNC were seen in all measurements, with the largest difference in the subcutaneous fat and the smallest difference in the erector spinae muscle. Only small differences were seen between VNCa and VNCv, where the largest differences were seen in the left and right liver lobes.

Conclusion: VNC images from the first-generation clinically approved PCCT showed a significant difference between VNC and TNC images. The differences vary with the type of tissue. Only small differences were seen depending from which contrast phase the VNC was derived.

背景:与标准计算机断层扫描(CT)相比,光子计数计算机断层扫描(PCCT)可实现新的图像重建方式,如材料分解和创建虚拟非对比(VNC)系列,具有更高的分辨率和更低的辐射剂量。目的:比较真正的非对比(TNC)序列与临床认可的 PCCT 中非增强(VNCu)、动脉期(VNCa)和门静脉期(VNCv)的 VNC 序列:回顾性评估了 2022 年 2 月至 2022 年 11 月期间 PCCT Naetom Alpha 共 45 次临床三相腹部 CT 扫描。在每个 VNC 系列的六个不同位置(右肝实质、左肝实质、脾脏、主动脉、竖脊肌和皮下脂肪)放置感兴趣区,收集绝对 Hounsfield 值(HU)和标准偏差(SD)。对 HU 的差异(ΔHU)进行比较和统计分析:结果:在所有测量中,VNC 和 TNC 之间的差异都具有统计学意义,其中皮下脂肪的差异最大,竖脊肌的差异最小。VNCa 和 VNCv 之间只有微小差异,其中左右肝叶的差异最大:结论:经临床批准的第一代 PCCT 的 VNC 图像显示,VNC 和 TNC 图像之间存在显著差异。差异因组织类型而异。根据 VNC 的对比相位不同,差异也很小。
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引用次数: 0
Call for a new Editor-in-Chief: Acta Radiologica / Acta Radiologica Open. 征集新主编:Acta Radiologica / Acta Radiologica Open。
IF 1.1 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-01 DOI: 10.1177/02841851241282945
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引用次数: 0
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Acta radiologica
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