Addictive behaviors最新文献_第5页

General executive functions, stimulus-specific inhibitory control and predisposing variables of individuals with problematic social network use 问题社交网络使用个体的一般执行功能、刺激特异性抑制控制和易感变量

IF 3.6 2区医学 Q1 PSYCHOLOGY, CLINICAL

Addictive behaviors

Pub Date : 2026-03-01 Epub Date: 2025-11-10 DOI: 10.1016/j.addbeh.2025.108556

Annica Kessling , Silke M. Müller , Astrid Müller , Matthias Brand , Elisa Wegmann

Background

General executive functions and decreased stimulus-specific inhibitory control may be relevant factors for the development and maintenance of problematic social network use (PSNU). Related predisposing variables that are risk factors for PSNU may include self-directedness, ADHD symptoms, or impulsivity, and as a result, social networks (SN) may be habitually utilized, which can manifest over time. Theoretical models suggest that interactions between predisposing factors and PSNU may influence neurocognitive deficits during problematic behavior. Therefore, we investigate possible interaction effects of SN use type (PSNU vs. non-problematic use) and predisposing factors on the expression of cognitive control mechanisms.

Method

In a laboratory setting, 227 participants were assigned to the group with PSNU (n = 118), or the control group (n = 109) using a structured diagnostic interview based on DSM-5 criteria for gaming disorder, modified for PSNU. General executive functions were examined with the Stroop task, the Modified Card Sorting Test and the Game of Dice Task; stimulus-specific inhibitory control with the Go/No-Go task. Self-directedness, ADHD symptoms, impulsivity and habitual SN use were determined by questionnaires.

Results

The SN use type (PSNU/non-problematic use) interacted with non-planning impulsivity in predicting impaired interference control, with ADHD symptoms in predicting cognitive inflexibility, and with habitual SN use in predicting decreased stimulus-specific inhibitory control.

Conclusions

Reductions in executive functioning in individuals with PSNU are specifically present in interaction with trait impulsivity and related variables. These results emphasize the need for multidimensional assessments that consider both cognitive and individual risk factors, paving the way for targeted prevention and intervention strategies.

背景：一般执行功能和刺激特异性抑制控制的减少可能是问题社交网络使用（PSNU）发展和维持的相关因素。作为PSNU风险因素的相关易感变量可能包括自我导向、ADHD症状或冲动，因此，社交网络（SN）可能被习惯性地利用，这可能随着时间的推移而显现出来。理论模型表明，易感因素和PSNU之间的相互作用可能影响问题行为期间的神经认知缺陷。因此，我们研究了社交网络使用类型（PSNU和非问题使用）和易感因素对认知控制机制表达的可能交互作用。方法在实验室环境中，采用基于针对PSNU修改的DSM-5游戏障碍标准的结构化诊断访谈，将227名参与者分为PSNU组（n = 118）和对照组（n = 109）。通过Stroop任务、改良卡片分类测试和骰子游戏任务检测一般执行功能；刺激特异性抑制控制与Go/No-Go任务。自我导向、ADHD症状、冲动性和习惯性SN使用采用问卷调查。结果SN使用类型（PSNU/无问题使用）与非计划性冲动性预测干扰控制受损，与ADHD症状预测认知不灵活性，与习惯性SN使用预测刺激特异性抑制控制下降。结论PSNU个体的执行功能下降与特质冲动性及相关变量的相互作用密切相关。这些结果强调需要进行多维评估，考虑认知和个人风险因素，为有针对性的预防和干预策略铺平道路。

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引用次数: 0

Perceptual distortions of social support in multi-age cohort as a function of internet addiction and attention control 网络成瘾与注意控制对多年龄群体社会支持知觉扭曲的影响

IF 3.6 2区医学 Q1 PSYCHOLOGY, CLINICAL

Addictive behaviors

Pub Date : 2026-03-01 Epub Date: 2025-11-22 DOI: 10.1016/j.addbeh.2025.108566

S.R. Sangeetha, Neriah Samraksha, Shreya M. Karakatti, D. Patteswari

Background

Internet addiction and attention control increasingly influence how individuals across age groups perceive social support. This study explored the psychological impact of excessive internet use and attentional regulation within a diverse Indian population.

Objectives

The study aimed (a) to examine perceptual distortions of social support across the lifespan as a function of individual differences in internet addiction and attention control; (b) to explore how socio-demographic factors such as sex and socioeconomic status (SES) influence attention control and perceived social support in the context of internet addiction; and (c) to investigate how age and SES jointly shape patterns of internet addiction, attention control, and perceived social support in a multi-age cohort.

Methods

A cross-sectional design was used to collect data from 399 participants in Mysuru through purposive sampling. Standardized instruments included the Internet Addiction Test, Attention Control Scale, and Multidimensional Scale of Perceived Social Support. Analyses were conducted using SPSS v.27, employing multiple regression and MANOVA.

Results

The regression model significantly predicted perceived social support, F(2, 396) = 20.87, p = 0.001, R² = 0.095. Internet addiction was a significant negative predictor of perceived social support (β = –.260, p = 0.001) meanwhile attention control was not (β = 0.099, p = 0.053). MANOVA showed significant effects of age (p = 0.013) and an Age × SES interaction (p = 0.019) on internet addiction. sex and SES main effects were non-significant.

Conclusion

Perceptual distortions of social support are not simply the result of screen time, but are mediated by age and class. These findings underscore internet addiction as a psychosocial outcome shaped by unequal digital environments.

网络成瘾和注意力控制越来越多地影响着不同年龄组的个体对社会支持的看法。本研究探讨了在不同的印度人口中过度使用互联网和注意力调节的心理影响。目的：本研究旨在(a)考察网络成瘾和注意力控制的个体差异对整个生命周期中社会支持的感知扭曲；(b)探讨性别和社会经济地位（SES）等社会人口因素如何影响网络成瘾背景下的注意控制和感知社会支持；(c)研究年龄和社会经济地位如何共同影响多年龄队列中网络成瘾、注意力控制和感知社会支持的模式。方法采用横断面设计，采用目的抽样的方法对399名参与者进行资料收集。标准化工具包括网络成瘾测试、注意控制量表和感知社会支持多维量表。采用SPSS v.27进行分析，采用多元回归和方差分析。结果回归模型显著预测感知社会支持，F(2,396) = 20.87, p = 0.001, R2 = 0.095。网络成瘾是感知社会支持的显著负向预测因子（β = -）。260, p = 0.001)，而注意控制不存在（β = 0.099, p = 0.053）。方差分析显示，年龄（p = 0.013）和年龄与社会经济地位的交互作用（p = 0.019）对网络成瘾有显著影响。性别和社会经济地位的主效应不显著。结论社会支持知觉扭曲不单纯是屏幕时间的结果，而受年龄和阶层的中介作用。这些发现强调了网络成瘾是由不平等的数字环境形成的一种社会心理后果。

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引用次数: 0

Social support, online social support, and problematic social media use: A three-level meta-analysis 社会支持、在线社会支持和有问题的社交媒体使用：一个三层次的元分析

IF 3.6 2区医学 Q1 PSYCHOLOGY, CLINICAL

Addictive behaviors

Pub Date : 2026-03-01 Epub Date: 2025-12-02 DOI: 10.1016/j.addbeh.2025.108579

Liangrong Huang , Miaomiao Zeng , Xue Wen

Numerous studies have examined the relationship between social support and problematic social media use; however, findings are inconsistent. Hence, this study employed a three-level meta-analysis to clarify the relationship between social support and problematic social media use. Additionally, a meta-analysis was conducted to examine the relationship between online social support and problematic social media use and to identify potential moderators of this relationship. After searching and screening the literature, this meta-analysis included a total of 65 studies, with 235 effect sizes and 52,738 participants. The results showed a negative correlation between social support and problematic social media use (r = -0.178, p < 0.001), and a positive correlation between online social support and problematic social media use (r = 0.399, p < 0.001). Age and educational stage significantly moderated the association between social support and problematic social media use. Online social support measurement and problematic social media use measurement significantly moderated the association between online social support and problematic social media use. It is suggested that treatment for problematic social media use should attend to individuals’ levels of social support and online social support.

许多研究已经调查了社会支持和有问题的社交媒体使用之间的关系；然而，研究结果并不一致。因此，本研究采用三层次元分析来阐明社会支持与问题社交媒体使用之间的关系。此外，还进行了一项荟萃分析，以检验在线社会支持与有问题的社交媒体使用之间的关系，并确定这种关系的潜在调节因素。在检索和筛选文献后，本荟萃分析共纳入65项研究，有235个效应量和52,738名参与者。结果显示，社会支持与问题社交媒体使用呈负相关（r = -0.178, p < 0.001），在线社会支持与问题社交媒体使用呈正相关（r = 0.399, p < 0.001）。年龄和教育阶段显著调节了社会支持与有问题的社交媒体使用之间的关系。在线社会支持测量和问题社交媒体使用测量显著调节了在线社会支持与问题社交媒体使用之间的关联。建议对社交媒体使用问题的治疗应关注个人的社会支持水平和在线社会支持水平。

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引用次数: 0

Prevalence of Internet gaming disorder in young adults: a systematic review and meta-analysis 青少年网络游戏障碍的流行：一项系统回顾和荟萃分析

IF 3.6 2区医学 Q1 PSYCHOLOGY, CLINICAL

Addictive behaviors

Pub Date : 2026-03-01 Epub Date: 2025-11-26 DOI: 10.1016/j.addbeh.2025.108576

Júlia Gisbert-Pérez , Claudio Longobardi , Manuel Martí-Vilar , Sofia Mastrokoukou , Laura Badenes-Ribera

Internet Gaming Disorder (IGD) is recognized as a condition for further study in DSM-5-TR and officially classified in ICD-11. Although gaming problems seem like an adolescent concern, growing evidence indicates that young adults are also vulnerable. This systematic review and meta-analysis aimed to estimate the global prevalence of IGD among young adults and identify sociodemographic and methodological moderators associated with its variability. Ninety-six analytical samples from 93 studies published (2015–2025) were included, comprising 149,601 participants aged 18–35 (M_age = 23.53 years, SD_age = 6.28; 51.22 % female). Generalized linear mixed models were applied to compute pooled prevalence estimates. The pooled prevalence of IGD was 6.1 % (95 % CI: 5.03–7.40). Prevalence was significantly higher in gamer-only samples (8.1 %, 95 % CI: 5.91–11.01) compared to mixed samples, including gamers and non-gamers (5.47 %, 95 % CI: 4.33–6.90). Moderator analyses showed that IGD prevalence differed by diagnostic instrument (IGDS and DSM-V criteria > IGDT-10) and by sample size, and a trend also emerged suggesting lower prevalence with higher proportions of women. In gamer-only samples, prevalence increased over time and in studies with a higher risk of bias. In mixed samples, prevalence differed by instrument (IGDS > GAS) and was negatively associated with sample size. These findings indicate that IGD is more prevalent among young adults than in the general population, especially among gamers. The variability observed across studies highlights the need for methodological consistency and the use of validated diagnostic tools to improve comparability and inform prevention and intervention strategies.

网络游戏障碍（IGD）在DSM-5-TR中被确认为需要进一步研究的疾病，并在ICD-11中被正式分类。虽然游戏问题似乎是青少年的问题，但越来越多的证据表明，年轻人也很容易受到影响。本系统综述和荟萃分析旨在估计年轻人中IGD的全球患病率，并确定与其变异性相关的社会人口统计学和方法学调节因素。纳入了来自93项已发表研究（2015-2025）的96个分析样本，包括149601名18-35岁的参与者（年龄= 23.53岁，年龄= 6.28岁，51.22%为女性）。应用广义线性混合模型计算合并患病率估计。IGD的总患病率为6.1% （95% CI: 5.03-7.40）。与包括玩家和非玩家的混合样本（5.47%,95% CI: 4.33-6.90）相比，仅游戏玩家样本的患病率明显更高（8.1%,95% CI: 5.91-11.01）。调节分析显示，IGD患病率因诊断工具（IGDS和DSM-V标准>； IGDT-10）和样本量而异，而且还出现了一种趋势，即女性比例较高，患病率较低。在仅针对游戏玩家的样本中，患病率随着时间的推移而增加，并且在偏见风险较高的研究中也会增加。在混合样本中，患病率因仪器（IGDS >； GAS）而异，并与样本量呈负相关。这些发现表明，IGD在年轻人中比在一般人群中更为普遍，尤其是在游戏玩家中。研究中观察到的可变性强调了方法一致性和使用经过验证的诊断工具的必要性，以提高可比性，并为预防和干预策略提供信息。

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引用次数: 0

Evaluating different patterns of problematic internet use using a unified self-report measure based on the ICD-11 framework: Psychometric properties of the Italian version of the ACSID-11 使用基于ICD-11框架的统一自我报告测量来评估有问题的互联网使用的不同模式：意大利版ACSID-11的心理测量特性。

IF 3.6 2区医学 Q1 PSYCHOLOGY, CLINICAL

Addictive behaviors

Pub Date : 2026-03-01 Epub Date: 2025-12-11 DOI: 10.1016/j.addbeh.2025.108580

Simon Ghinassi , Giulia Fioravanti , Maria Anna Donati , Caterina Primi , Yura Loscalzo , Silvia Casale

The ACSID-11 was developed to assess five patterns of problematic Internet use—namely, gaming disorder, compulsive online shopping, problematic online pornography use, problematic social networks use, and online gambling disorder—using a unified set of items grounded in the ICD-11 framework. The present study examined the psychometric properties of the Italian version of the ACSID-11. A sample of 1263 participants (76.70 % females, M_age = 40.89, SD = 13.72, range = 18–83) completed the ACSID-11 and was included in the analysis of its factorial structure. A series of Confirmatory Factor Analyses (CFAs) confirmed the assumed four-factorial structure (i.e., Impaired Control, Increased Priority, Continuation/Escalation of Use, Functional Impairment in Daily Life/Marked Distress), which was superior to the unidimensional solution for all the patterns of problematic Internet use. Moreover, the second-order models demonstrated comparable fit to the four-factor solutions and supported the use of an overall composite score. A subsample of 999 participants (76.40 % females, M = 40.59, SD = 13.67, range = 18–83) also completed the Patient Health Questionnaire-9, the General Anxiety Disorder Scale-7, and the Satisfaction with Life Scale, whereas the number of participants who completed the measures used to assess convergent validity varied depending on whether they reported engaging in the corresponding behavior or not. Convergent and criterion validity were supported. These findings suggest that the Italian version of this unified item set is a valid and reliable tool for consistently assessing different patterns of problematic Internet use.

制定ACSID-11是为了评估有问题的互联网使用的五种模式，即游戏障碍、强迫性在线购物、有问题的在线色情使用、有问题的社交网络使用和在线赌博障碍，使用的是基于ICD-11框架的一套统一项目。本研究考察了意大利版ACSID-11的心理测量特性。1263名参与者（76.70%为女性，Mage = 40.89, SD = 13.72, range = 18-83）完成了ACSID-11，并纳入其析因结构分析。一系列验证性因子分析（CFAs）证实了假设的四因子结构（即控制障碍，优先级增加，使用的持续/升级，日常生活功能障碍/明显的痛苦），对于所有有问题的互联网使用模式，这优于单维解决方案。此外，二阶模型显示出与四因素解决方案相当的拟合性，并支持使用综合评分。999名参与者的子样本（76.40%为女性，M = 40.59, SD = 13.67，范围= 18-83）还完成了患者健康问卷-9，一般焦虑障碍量表-7和生活满意度量表，而完成用于评估收敛效度的措施的参与者数量取决于他们是否报告从事相应的行为。支持收敛效度和标准效度。这些发现表明，这个统一项目集的意大利语版本是一个有效和可靠的工具，用于一致地评估不同的有问题的互联网使用模式。

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引用次数: 0

Smartphone restriction modulates intrinsic neural activity in problematic smartphone users: Evidence from resting-state fMRI 智能手机限制调节问题智能手机用户的内在神经活动：来自静息状态功能磁共振成像的证据。

IF 3.6 2区医学 Q1 PSYCHOLOGY, CLINICAL

Addictive behaviors

Pub Date : 2026-03-01 Epub Date: 2025-11-27 DOI: 10.1016/j.addbeh.2025.108575

Sophie H. Haage , Mike M. Schmitgen , Gudrun M. Henemann , Julian Koenig , Marie-Luise Otte , Patrick Bach , Nadine D. Wolf , Robert Christian Wolf

Problematic smartphone use (PSU) has been associated with withdrawal-like symptoms and altered intrinsic neural activity (INA). While previous studies suggest that PSU affects brain function, little is known about how INA is modulated by smartphone restriction. This longitudinal fMRI study investigated group- and time-dependent changes in resting-state INA following short-term smartphone deprivation. 36 participants (aged 18–29; 22 female) were categorized into PSU (n = 19) and non-PSU (n = 17) groups using the Smartphone Addiction Scale–Short Version (SAS-SV). Resting-state fMRI scans were obtained before and after a 72-hour period of smartphone restriction. Psychometric measures included the Mannheim Craving Scale (MaCS) and the Smartphone Addiction Inventory (SPAI). A significant group-by-time interaction revealed INA changes in the left inferior frontal gyrus, bilateral posterior cingulate cortex, right middle frontal and precentral gyri, and left calcarine cortex. INA increased over time in the non-PSU group but decreased in the PSU group in prefrontal and cingulate areas. In contrast, sensorimotor and occipital regions showed increased INA over time in PSU individuals. Associations between neural activity and MaCS scores indicated that greater craving was linked to reduced INA in the posterior cingulate cortex. Within the PSU group, higher smartphone-use severity, as measured by the SPAI, was associated with altered INA in occipital, parietal, and cerebellar regions. These findings suggest PSU is linked to distinct and state-dependent neurofunctional alterations that may reflect withdrawal-related processes and maladaptive reward and cognitive control mechanisms.

有问题的智能手机使用（PSU）与戒断样症状和内在神经活动（INA）的改变有关。虽然之前的研究表明PSU会影响大脑功能，但人们对限制使用智能手机如何调节INA知之甚少。这项纵向fMRI研究调查了短期智能手机剥夺后静息状态INA的组和时间依赖性变化。36名参与者（18-29岁，22名女性）使用智能手机成瘾量表-短版本（SAS-SV）分为PSU组（n = 19）和非PSU组（n = 17）。在限制使用智能手机72小时之前和之后，分别获得静息状态fMRI扫描。心理测量包括曼海姆渴望量表（MaCS）和智能手机成瘾量表（SPAI）。显著的组-时间交互作用显示，INA在左侧额下回、双侧后扣带皮层、右侧额中回和中央前回以及左侧脑胼胝体皮层发生改变。随着时间的推移，非PSU组的INA增加，而PSU组的前额叶和扣带区INA减少。相比之下，PSU个体的感觉运动区和枕区随着时间的推移显示INA增加。神经活动和MaCS评分之间的关联表明，更大的渴望与后扣带皮层INA减少有关。在PSU组中，SPAI测量的更高的智能手机使用严重程度与枕部、顶叶和小脑区域的INA改变有关。这些发现表明，PSU与不同的和状态依赖性的神经功能改变有关，这些改变可能反映了戒断相关的过程和不适应的奖励和认知控制机制。

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引用次数: 0

Hippocampal transcranial temporal interference stimulation reduced craving in methamphetamine use disorder 海马经颅颞叶干扰刺激减少甲基苯丙胺使用障碍的渴求

IF 3.6 2区医学 Q1 PSYCHOLOGY, CLINICAL

Addictive behaviors

Pub Date : 2026-03-01 Epub Date: 2025-12-11 DOI: 10.1016/j.addbeh.2025.108581

Dongcheng Wang , Zhe Du , Xinwen Wen , Qihan Li , Yi Liu , Junjie Tang , Chunhao Shui , Peijie Yu , Likun Yang , Pengquan Tu , Xin Liu , Cunfeng Yuan , Dahua Yu , Tengfei Ma , Kai Yuan

Background

Craving is a key challenge in treating methamphetamine use disorder (MUD). The memory reconsolidation theory indicates that interference with MUD after drug memory retrieval helps to reduce craving. Previous studies have demonstrated the importance of the hippocampus in memory consolidation, but traditional non-invasive interventions cannot effectively locate and intervene in the hippocampus. Although tTIS can accurately intervene in deep brain regions, it is still unknown whether tTIS intervention on the MUD hippocampus is effective in reducing craving.

Method

A total of 40 male participants with MUD were randomized to active or sham tTIS. Active tTIS delivered a 10 Hz electric field to the hippocampus for 20 min per day over 10 consecutive days, while sham stimulation lasted only 1 min per day during the same period. We also assessed its effects on craving, cognitive function and emotional symptoms at baseline, post intervention and one month follow-up.

Results

A two-way repeated-measures analysis of variances (ANOVAs) on drug cue-induced craving revealed a significant group × time interaction effect (F (2, 108) = 5.652, P = 0.005). Post hoc paired t-test indicated a significant decrease in craving in the active tTIS group (t = 5.04, P = 0.002) after the intervention and one month follow-up (t = 6.04, P < 0.001). In contrast, no significant changes were observed in the sham group.

Conclusions

In this trial, 10 Hz tTIS was effective for METH craving reduction in MUD. Further trials are needed to explore neural mechanisms of tTIS.

渴望是治疗甲基苯丙胺使用障碍（MUD）的一个关键挑战。记忆再巩固理论表明，药物记忆提取后对MUD的干扰有助于减少渴望。以往的研究已经证明了海马体在记忆巩固中的重要性，但传统的非侵入性干预无法有效定位和干预海马体。虽然tTIS可以准确地干预脑深部区域，但tTIS对MUD海马的干预是否能有效减少渴望仍是未知的。方法将40名男性MUD患者随机分为活动性或假性tTIS组。在连续10天内，活跃的tTIS每天向海马体提供20分钟的10 Hz电场，而假性刺激在同一时间段内每天仅持续1分钟。我们还在基线、干预后和一个月随访时评估了其对渴望、认知功能和情绪症状的影响。结果对药物线索诱导的渴求进行双向重复测量方差分析（ANOVAs），发现组×时间交互作用显著（F (2,108) = 5.652, P = 0.005）。事后配对t检验显示，在干预和随访1个月后，活跃tTIS组的渴望显著降低（t = 5.04, P = 0.002）（t = 6.04, P < 0.001）。相比之下，假手术组未见明显变化。结论在本试验中，10hz tTIS可有效降低吸毒者对甲基苯丙胺的渴望。需要进一步的试验来探索tTIS的神经机制。

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引用次数: 0

Alcohol demand and alcohol use disorder among adolescents and young adults who drink heavily: An exploratory analysis including sex differences 酗酒的青少年和年轻人的酒精需求和酒精使用障碍：包括性别差异的探索性分析

IF 3.6 2区医学 Q1 PSYCHOLOGY, CLINICAL

Addictive behaviors

Pub Date : 2026-03-01 Epub Date: 2025-12-11 DOI: 10.1016/j.addbeh.2025.108583

Kathryn S. Gex , ReJoyce Green , Samuel F. Acuff , Anna E. Kirkland , Brittney D. Browning , Rachel L. Tomko , Kevin M. Gray , Lindsay M. Squeglia

Behavioral economic alcohol demand, or the reward value of alcohol consumption, consistently shows associations between alcohol use and alcohol use disorder (AUD) in adults, yet research within clinical youth populations (considered to be ages 15–24) remains limited. It is critical to better understand how demand functions in clinical youth populations to predict alcohol related outcomes. Moreover, given the narrowing gap between male and female youth in alcohol use prevalence in recent years, exploring sex differences in alcohol demand and its role in the relationship between demand, alcohol use, alcohol-related problems, and AUD is important. The current study used data from two samples of adolescents and young adults from the community (N = 127; ages 16–25, M_age = 20.57, SD = 2.27; 56.35 % female; 91.27 % white), one treatment seeking (n = 94) and one non-treatment seeking (n = 33), to examine the relationship between demand indices and alcohol use outcomes and to explore the role of sex in these relationships. Demand intensity (the number of standard drinks a person would consume if drinks were $0), O_max (maximum money spent across prices, i.e., number of drinks purchased × price), and price sensitivity (α; the rate alcohol consumption decreases as prices increase) were significantly associated with alcohol use quantity and frequency outcomes, but not alcohol-related problems or AUD severity. Although male youth had significantly greater intensity relative to female youth, intensity was more strongly associated with drinking days in female youth. Broadly, our findings support the importance of evaluating alcohol demand in clinical youth as well as sex differences in alcohol demand. Our results also speak to the need for interventions targeting sex-specific mechanisms and moderators of alcohol use.

行为经济酒精需求，或酒精消费的奖励价值，一致显示酒精使用与成人酒精使用障碍（AUD）之间的关联，但在临床青年人群（被认为是15-24岁）中的研究仍然有限。更好地了解临床青年人群的需求如何发挥作用以预测酒精相关结果至关重要。此外，鉴于近年来男性和女性青年在酒精使用患病率方面的差距正在缩小，探索酒精需求的性别差异及其在需求、酒精使用、酒精相关问题和AUD之间的关系中的作用非常重要。目前的研究使用了来自社区的两个青少年和年轻人样本（N = 127，年龄16-25岁，Mage = 20.57, SD = 2.27, 56.35%女性，91.27%白人），一个寻求治疗（N = 94）和一个非寻求治疗（N = 33）的数据，以检验需求指数与酒精使用结果之间的关系，并探讨性别在这些关系中的作用。需求强度（如果饮料价格为0美元，一个人将消费的标准饮料数量）、Omax（各种价格的最大消费金额，即购买的饮料数量×价格）和价格敏感性（α；酒精消费量随价格上涨而下降的速度）与酒精使用数量和频率结果显著相关，但与酒精相关问题或AUD严重程度无关。尽管男性青年的强度明显高于女性青年，但强度与女性青年的饮酒天数关系更强。总的来说，我们的研究结果支持了评估临床青年酒精需求的重要性，以及酒精需求的性别差异。我们的研究结果也说明了针对酒精使用的性别特异性机制和调节因素进行干预的必要性。

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引用次数: 0

Smartphones are not addictive: a proposal to distinguish between rewards and reward delivery vehicles 智能手机不会让人上瘾：一项区分奖励和奖励递送工具的建议

IF 3.6 2区医学 Q1 PSYCHOLOGY, CLINICAL

Addictive behaviors

Pub Date : 2026-03-01 Epub Date: 2025-12-11 DOI: 10.1016/j.addbeh.2025.108585

Dar Meshi , Jens Binder

引用次数: 0

Working memory capacity predicts cannabis-induced effects on alcohol urge 工作记忆容量可以预测大麻对酒精冲动的影响

IF 3.6 2区医学 Q1 PSYCHOLOGY, CLINICAL

Addictive behaviors

Pub Date : 2026-03-01 Epub Date: 2025-11-19 DOI: 10.1016/j.addbeh.2025.108565

Rachel L. Gunn , Lindy K. Howe , Holly K. Boyle , Jane Metrik

Background

Cannabis has shown mixed results in its association with alcohol urge, which may be explained by individual differences. One such factor, working memory capacity (WMC) is associated with drug-related cue reactivity and implicated in alcohol use and problems. In the current study, we examined whether WMC moderates the acute effect of cannabis on alcohol urge in a randomized placebo-controlled crossover trial.

Methods

Participants aged 21 to 44 (N = 125, 32 % female) reporting heavy alcohol use and cannabis use ≥ twice weekly completed a laboratory protocol across three days where they smoked a placebo, 3.1 % delta-9 tetrahydrocannabinol (THC), and 7.2 % THC cannabis cigarette. Participants were asked to rate their alcohol urge pre and post smoking. Prior to the experimental sessions, participants completed WMC measures including the n-back and the complex span tasks, operation span (OS) and symmetry span (SS).

Results

Those with higher WMC, as assessed via the SS task, reported significantly lower alcohol urge after smoking the 7.2 %, but not the 3.1 %, THC dose, relative to placebo. Performance on the OS task was not associated with alcohol urge. Lower WMC as determined via n-back scores was associated with higher alcohol urge overall, but n-back scores did not moderate the impact of cannabis on alcohol urge.

Conclusion

Findings suggest individuals with higher but not lower working memory experience lower alcohol urge under acute effects of cannabis. Although cannabis is increasingly perceived as a substitute for alcohol, individuals with lower working memory may be less likely to experience such benefits when attempting to reduce their drinking.

大麻与酒精冲动的关系显示出不同的结果，这可以用个体差异来解释。其中一个因素是，工作记忆容量（WMC）与药物相关的线索反应有关，并与酒精的使用和问题有关。在当前的研究中，我们在一项随机安慰剂对照交叉试验中研究了WMC是否能调节大麻对酒精冲动的急性影响。方法年龄在21岁至44岁之间（N = 125, 32%为女性）报告重度饮酒和大麻使用≥每周两次，完成为期三天的实验室方案，其中他们吸食安慰剂，3.1% δ -9四氢大麻酚（THC）和7.2% THC大麻烟。参与者被要求对吸烟前和吸烟后的酒精冲动进行评分。实验前，被试完成了n-back和复杂跨度任务、操作跨度（OS）和对称跨度（SS）。结果通过SS任务评估的WMC较高的受试者在吸烟7.2% THC剂量后的酒精冲动显著降低，而在吸烟3.1% THC剂量后的酒精冲动则显著降低。在OS任务中的表现与酒精冲动无关。通过n-back评分确定的较低的WMC总体上与较高的酒精冲动有关，但n-back评分并没有缓和大麻对酒精冲动的影响。结论在大麻的急性作用下，工作记忆较高而非较低的个体酒精冲动较低。虽然大麻越来越被认为是酒精的替代品，但工作记忆较差的人在试图减少饮酒量时可能不太可能体验到这种好处。

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