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Bilateral Nasolacrimal Duct Congenital Mucocele in a Newborn 新生儿双侧鼻泪管先天性黏液瘤
Pub Date : 2024-04-10 DOI: 10.29011/2574-7754.101752
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引用次数: 0
Emerging Evidence for the Effectiveness of Profhilo® Figura Body Cream in Enhancing Skin Hydration, Elasticity, and Firmness Profhilo® Figura 身体乳在增强皮肤水合性、弹性和紧致度方面的功效新证据
Pub Date : 2024-04-04 DOI: 10.29011/2574-7754.101743
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引用次数: 0
Association of Dyslipidemia in Decreased Glomerular Filtration Rate in Patients with CKD KDIGO ≥ 3 血脂异常与慢性肾功能衰竭 KDIGO ≥ 3 患者肾小球滤过率降低的关系
Pub Date : 2024-04-03 DOI: 10.29011/2574-7754.101740
Zayra Carolina, Rojas Castillo, Elizabeth Ruíz López, Moisés Moreno Noguez, Eleane Daniela Solorio Adame, Blanca Estela, Herrera Morales, Luis Rey, García Cortés, Olga Lidia, Toxqui Delgado, Victor Itai, Urbalejo Ceniceros, Dana Aline Pérez Camargo, Victor Manuel Enriquez Estrada, María Rebeca Velasco Domínguez
Objective. To determine the association of dyslipidemia with decreased glomerular filtration rate (eGFR) in patients with CKD KDIGO ≥3. Material and methods. Observational, analytical, longitudinal, ambispective study; was carried out at the Family Medicine Unit (UMF) No. 55 Zumpango, the sample size was calculated using the mean difference formula, with an expected mean of 5.2, obtaining n= 90 patients with CKD KDIGO ≥3 , between 20-69 years. Patients with dyslipidemia and without dyslipidemia were classified into 2 groups, in which creatinine was evaluated to calculate the estimated glomerular filtration rate (eGFR), total cholesterol and triglycerides, subjects with renal function replacement therapy, patients with pathologies or treatments that modify lipid metabolism. For the bivariate analysis, the Student’s T test and the Mann-Whitney U test were applied according to the type of distribution presented by the eGFR values for the groups with and without dyslipidemia. Result and conclusion. Based on the eGFR values for the groups with and without dyslipidemia, they show that patients aged 20 to 69 years with CKD KDIGO ≥ 3 with dyslipidemia presented a mean eGFR of 40.24 for the first analysis, and 34.70 for the follow-up analysis., with a mean difference of 5.53, which was significant (p=0.003).
目的确定血脂异常与 CKD KDIGO≥3 患者肾小球滤过率(eGFR)下降的关系。材料和方法。观察性、分析性、纵向、前瞻性研究;在 Zumpango 第 55 号家庭医学科(UMF)进行,样本量使用平均差公式计算,预期平均值为 5.2,共获得 90 名 20-69 岁的 CKD KDIGO ≥3 患者。将有血脂异常和无血脂异常的患者分为两组,其中评估肌酐以计算估计肾小球滤过率(eGFR)、总胆固醇和甘油三酯、接受肾功能替代治疗的受试者、有改变脂质代谢的病变或治疗的患者。在双变量分析中,根据血脂异常组和非血脂异常组 eGFR 值的分布类型,采用了学生 T 检验和曼-惠特尼 U 检验。结果和结论。根据血脂异常组和无血脂异常组的 eGFR 值显示,20 至 69 岁的 CKD KDIGO≥3 且伴有血脂异常的患者,首次分析的平均 eGFR 值为 40.24,随访分析的平均 eGFR 值为 34.70,平均差为 5.53,差异显著(P=0.003)。
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引用次数: 0
Analgesic Effect of Intraperitoneal Bupivacaine in Laparoscopic Sleeve Gastrectomy: A Matched Case-Control Study and Review of Available Data 腹腔镜袖带胃切除术中腹腔内布比卡因的镇痛效果:一项匹配病例对照研究和现有数据回顾
Pub Date : 2024-04-02 DOI: 10.29011/2574-7754.101732
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引用次数: 0
Cerebellar Abscess Following Craniocervical Junction Decompression for Chiari I Malformation in a Patient with Rheumatoid Arthritis: A Case Report 类风湿性关节炎患者因脊髓Ⅰ型畸形接受颅颈交界处减压术后出现小脑脓肿:病例报告
Pub Date : 2024-04-02 DOI: 10.29011/25747754.101733
Andreas Papacharalampous, Theoklis Kouyialis, Petros Stylianou
‘Chiari Malformations’ are a group of pathologies involving the Craniocervical junction. The most common is Chiari I malformation (CIM), which is characterised by a downward dislocation of the cerebellar tonsils through the foramen magnum. Symptomatic patients and those with syringomyelia are candidates for decompression of the Craniocervical junction. A variety of complications have been described in the literature following this procedure. We present the case of a cerebellar abscess following Craniocervical junction decompression for CIM in a patient with rheumatoid arthritis (RA), which, in our knowledge, is the first described in the literature. We believe that RA and its treatment were major contributors to this complication, mainly due to the immune impairment and the subtle infectious clinical manifestations that they cause. This case led us to modify the perioperative management of patients with RA who undergo spinal surgery in our department. We suggest that strict infection prevention measures should be taken by spine surgeons who treat patients with RA and a high suspicion index for infection should be maintained.
奇拉氏畸形 "是一组涉及颅颈交界处的病变。最常见的是Chiari I畸形(CIM),其特征是小脑扁桃体通过枕骨大孔向下脱位。有症状的患者和患有鞘膜积液的患者都适合进行颅颈交界处减压术。文献中描述了这种手术后的各种并发症。据我们所知,这是文献中首次描述类风湿性关节炎(RA)患者在接受颅颈交界处减压术治疗 CIM 后出现小脑脓肿的病例。我们认为,类风湿性关节炎及其治疗是导致这一并发症的主要原因,这主要是由于类风湿性关节炎导致的免疫功能损害和微妙的感染性临床表现。该病例促使我们改变了我科对接受脊柱手术的 RA 患者的围手术期管理。我们建议脊柱外科医生在治疗RA患者时应采取严格的感染预防措施,并对感染保持高度怀疑。
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引用次数: 0
Hyperbaric Oxygen Therapy for Military Post-Traumatic Stress Disorder in Elderly Veterans: Case Studies, Literature Review, and Discussion 高压氧疗法治疗老年退伍军人的军事创伤后应激障碍:病例研究、文献综述与讨论
Pub Date : 2024-04-02 DOI: 10.29011/2574-7754.101729
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引用次数: 0
Early-Age Orthodontic Treatment: An Approach with “Prefabricated Aligners” Combined with Myofunctional Therapy - Two Case Reports 早期正畸治疗:预制矫治器 "与肌功能疗法相结合的方法 - 两份病例报告
Pub Date : 2024-04-01 DOI: 10.29011/2574-7754.101727
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引用次数: 0
Recognizing Granulomatosis with Polyangiitis in Bullous Purpura Presentations 在大疱性紫癜表现中识别多发性肉芽肿病
Pub Date : 2024-04-01 DOI: 10.29011/2574-7754.101723
Manjushree Shanmugasundaram, Rebekah Brown, Meghana Koleti, Anita C Mercado
Granulomatosis with polyangiitis has a variable presentation making diagnosis difficult as it can be mistaken for IgA vasculitis which presents similarly. We report a case of granulomatosis with polyangiitis presenting with a bullous rash. Our patient was admitted for bullous purpura to the extremities, and reported symptoms of sinus infection, productive cough
肉芽肿伴多血管炎的表现形式多变,容易被误诊为表现相似的 IgA 血管炎,因此诊断困难。我们报告了一例伴有多血管炎的肉芽肿病,表现为大牛皮疹。患者因四肢出现大泡性紫癜而入院,并报告了鼻窦感染、有痰咳嗽等症状。
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引用次数: 0
Ten Years Survival in a Patient with Brain and Meningeal Metastases from ALK-Positive Lung Cancer Treated with Five Lines of Therapy: A Case Report 五线疗法治疗 ALK 阳性肺癌脑转移灶和脑膜转移灶患者的十年生存率:病例报告
Pub Date : 2024-03-25 DOI: 10.29011/2574-7754.101711
Wanda Liguigli, Roberto Barbieri, R. Cengarle, Anita Rimanti, Giovanna Catania, Francesca Turina, Camilla Pesoni, Maurizio Cantore
Anaplastic lymphoma kinase (ALK) translocation is observed in 4–5% of lung adenocarcinoma patients. In October 2012, we diagnosed a translocated ALK lung adenocarcinoma with pleural and bone metastases in a 42-year-old woman. After 16 months of chemotherapy, due to progression of the abdominal lymph nodes, the patient started Crizotinib. After 28 months, brain MRI documented progression of brain disease and a CT scan showed lung progression. The patient underwent whole-brain radiotherapy and Ceritinib was started but discontinued after six months due to grade 3 gastrointestinal toxicity. In June 2017, progression of meningeal disease was documented and the patient started Brigatinib. After 41 months the brain CT scan showed multiple lesions and Lorlatinib was started. The patient is still continuing this therapy while maintaining a good quality of life. The advent of ALK inhibitors has changed the prognosis of these patients even in cases of cerebral and meningeal metastatic disease.
4%-5%的肺腺癌患者会出现无性淋巴瘤激酶(ALK)易位。2012年10月,我们诊断出一名42岁女性患有ALK易位肺腺癌,并伴有胸膜和骨转移。化疗16个月后,由于腹腔淋巴结进展,患者开始接受克唑替尼治疗。28 个月后,脑部磁共振成像显示脑部疾病进展,CT 扫描显示肺部疾病进展。患者接受了全脑放疗,并开始服用色瑞替尼,但六个月后因3级胃肠道毒性而停药。2017年6月,记录到脑膜疾病进展,患者开始服用布加替尼。41个月后,脑部CT扫描显示多处病变,于是开始使用乐拉替尼。患者目前仍在继续接受治疗,同时保持良好的生活质量。ALK抑制剂的出现改变了这些患者的预后,即使是脑和脑膜转移性疾病患者。
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引用次数: 0
Atypical Presentation of Rheumatoid Arthritis with Erythema Nodosum Mimicking Cellulitis: A Case Report 类风湿性关节炎伴结节性红斑的非典型表现,酷似蜂窝组织炎:病例报告
Pub Date : 2024-03-25 DOI: 10.29011/2574-7754.101714
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引用次数: 0
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Annals of case reports
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