Archives of rehabilitation research and clinical translation最新文献

{"title":"Impact of Pneumonia on Rehabilitation Outcomes: A Large Observational Study","authors":"Van Giap Vu PhD ,&nbsp;Thi Linh Tran MMed ,&nbsp;Viet Phuong Dao PhD ,&nbsp;Xuan Trien Vu MSc ,&nbsp;Le Huyen Mai MMed ,&nbsp;Thi Thu Ha Bui MSc ,&nbsp;Thi Minh Thanh Vu MD ,&nbsp;Dao Quang Do BPT ,&nbsp;Thi Thanh Huyen Tran PhD ,&nbsp;Dao Vu Do PhD","doi":"10.1016/j.arrct.2025.100569","DOIUrl":"10.1016/j.arrct.2025.100569","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the effect of poststroke pneumonia on rehabilitation outcomes in patients with acute stroke.</div></div><div><h3>Design</h3><div>A prospective observational cohort study.</div></div><div><h3>Setting</h3><div>Rehabilitation services for patients with stroke across 3 hospitals in a low and middle-income country.</div></div><div><h3>Participants</h3><div>A total of 922 patients with stroke (N=922) were enrolled (median age: 67y; 63.7% men) and classified into poststroke pneumonia (PSP; n=296) and nonpneumonia (PSNP; n=626) groups. The patients with PSP were further divided into 2 subgroups based on onset timing including stroke-associated pneumonia (SAP; n=157), defined as diagnosis within 7 days of stroke onset, and hospital-acquired pneumonia (HAP; n=139), defined as pneumonia diagnosed after 7 days.</div></div><div><h3>Interventions</h3><div>Not applicable.</div></div><div><h3>Main Outcome Measures</h3><div>Primary outcome analysis focused on functional outcomes (modified Rankin Scale [mRS]), hospital length of stay (LOS), and mortality were assessed at discharge, 3 months, and 6 months after stroke. Secondary analysis explored predictors of functional outcomes.</div></div><div><h3>Results</h3><div>Patients with PSP demonstrated significantly poorer functional outcomes, with higher mRS scores (≥3) at discharge, 3 months, and 6 months (<em>P</em>&lt;.001). However, HAP showed stronger association with poor outcomes (odds ratio [OR]≥3) than SAP. Mortality was higher in the PSP group compared with the PSNP group at 3 months (OR=4.98; 95% CI, 2.1-11.7, <em>P</em>&lt;.001) and 6 months after stroke (OR=5.4; 95% CI, 2.3-12.6, <em>P</em>&lt;.001). HAP also associated with a longer LOS (24.18±7.81d) than SAP (19.5±8.26d; <em>P</em>&lt;.001). Stroke severity remained a strong predictor of outcomes in this study.</div></div><div><h3>Conclusions</h3><div>Poststroke pneumonia worsens rehabilitation outcomes, prolongs LOS, and increases mortality. Early pneumonia prevention and multidisciplinary integrated rehabilitation, aligned with World Health Organization (WHO) standards, are essential to improve stroke recovery and reduce complications in low- and middle-income countries.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"8 1","pages":"Article 100569"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147428873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of the AM-PAC 6 Clicks Basic Mobility Short Forms as a Measure of Functional Change in the Pediatric Heart Failure Population","authors":"Amanda Waples PT, DPT,&nbsp;Samuel R. Pierce PT, PhD,&nbsp;Julie Orlando PT, DPT, PhD","doi":"10.1016/j.arrct.2025.100575","DOIUrl":"10.1016/j.arrct.2025.100575","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the responsiveness of the 6 Clicks Basic Mobility Short Form (BMSF) and Basic Mobility Short Form – Low Function (BMSF-LF) in children with heart failure (HF) and to assess the correlations of the BMSF with the 6-Minute Walk Test (6MWT) and the 60-Second Sit-to-Stand (60sSTS) test.</div></div><div><h3>Design</h3><div>Retrospective cohort study.</div></div><div><h3>Setting</h3><div>Inpatient acute cardiac center in a large, urban children’s hospital.</div></div><div><h3>Participants</h3><div>Sixty-six participants (N=66) between 1 and 21 years of age with a diagnosis of pediatric HF and at least 2 documented BMSF and/or BMSF-LF in the electronic medical record. Chart reviews were completed for each participant to determine if change was a result of functional improvement or a change in medical status resulting in functional decline. Data for the 60sSTS and 6MWT were included if completed within 48 hours of a documented BMSF. Thirty participants completed a 60sSTS and 21 participants completed a 6MWT.</div></div><div><h3>Interventions</h3><div>Not applicable.</div></div><div><h3>Main Outcome Measures</h3><div>BMSF, BMSF-LF, 6MWT, and 60sSTS.</div></div><div><h3>Results</h3><div>Large effect sizes as measured by standardized response mean (SRM) were found for both the BMSF (SRM=0.96) and BMSF-LF (SRM=1.07) for functional improvement as well as for functional decline with the BMSF (SRM=-1.35) and BMSF-LF (SRM=-1.34). There was a significant, moderate positive correlation between the BMSF and the 6MWT distance (ρ=0.47, <em>P</em>=.048) and a moderate correlation between the BMSF and 60sSTS repetitions that did not reach significance (ρ=0.35, <em>P</em>=.070).</div></div><div><h3>Conclusions</h3><div>The 6 Clicks BMSF and BMSF-LF demonstrate excellent responsiveness to both functional improvement and functional decline in pediatric patients with HF. The moderate correlation between the BMSF and the 6MWT suggests a positive association between performance-based endurance testing and functional status.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"8 1","pages":"Article 100575"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147428875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neural Effects of Low-Frequency Acupoint Electrical Stimulation Therapy on Patients With Poststroke Motor Dysfunction: A Resting-State Functional Magnetic Resonance Imaging Study","authors":"Dongxia Li MD ,&nbsp;Hong Huo MD ,&nbsp;Yihao Zhou MD ,&nbsp;Siyu Yang MD ,&nbsp;Wenqiang Li MM ,&nbsp;Jingyi Li MD ,&nbsp;Yue Liu MD ,&nbsp;Dongyan Wang MD","doi":"10.1016/j.arrct.2025.100574","DOIUrl":"10.1016/j.arrct.2025.100574","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate differences in brain functional activity between patients with poststroke motor dysfunction and healthy individuals, and to examine the effects of low-frequency acupoint electrical stimulation on brain regional homogeneity (ReHo) in patients.</div></div><div><h3>Design</h3><div>This was a case-control study.</div></div><div><h3>Setting</h3><div>The study was conducted in a local tertiary hospital.</div></div><div><h3>Participants</h3><div>Twenty-eight patients with poststroke motor dysfunction (infarcts in the right basal ganglia region; 19 men, 9 women; mean age 59.07±9.03y) were recruited to form the Treatment group (Tx). Concurrently, 20 age- and gender-matched healthy controls (HCs) were recruited (14 men and 6 women, with an average age of 57.60±8.36y).</div></div><div><h3>Interventions</h3><div>The Tx received low-frequency acupoint electrical stimulation. Scalp Acupoint Selection: motor area on the affected hemisphere. Limb Acupoint Selection: acupoints on the affected limb, forming the following pairs: Shousanli (LI10) – Waiguan (SJ5); Ximen (PC4) – Neiguan (PC6); Zusanli (ST36) – Shangjuxu (ST37); and Heyang (BL55) – Chengshan (BL57). Head: frequency 2 Hz, pulse width 100 µs, and intensity 1.5 mA. Upper limb: frequency 35 Hz, pulse width 200 µs, and intensity 40 mA. Lower limb: frequency 50 Hz, pulse width 400 µs, and intensity 40 mA. Each session lasted 30 minutes, administered once daily for 6 sessions per week over 3 weeks.</div></div><div><h3>Main Outcome Measures</h3><div>The primary endpoint was the improvement from baseline in ReHo for patients with stroke at 3 weeks.</div></div><div><h3>Results</h3><div>Compared with HCs, patients with stroke showed increased ReHo in the bilateral parahippocampal gyrus, bilateral cerebellum, and cerebellar vermis, whereas ReHo decreased in sensorimotor network (SMN)-related brain regions (false discovery rate [FDR]-corrected, <em>P</em>&lt;.05). After intervention, ReHo increased in the right SMN-related brain regions, whereas ReHo decreased in the left cerebellum and left angular gyrus (FDR-corrected, <em>P</em>&lt;.05). Right precentral gyrus ReHo changes positively correlated with Fugl-Meyer Assessment improvement. Left cerebellum ReHo changes positively correlated with Modified Barthel Index improvement but negatively with National Institute of Health Stroke Scale improvement. Other regions showed no significant correlation.</div></div><div><h3>Conclusions</h3><div>Abnormal synchrony between SMN and cerebellum may be a key pathologic feature in poststroke motor dysfunction. Lateralized SMN functional remodeling is a potential neural mechanism for motor recovery via low-frequency acupoint electrical stimulation.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"8 1","pages":"Article 100574"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147428609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and Benefits of Moderate to High Intensity Aerobic Exercise During the Subacute Phase of Stroke: A Systematic Review and Meta-analysis","authors":"Erin Y. Harmon PhD ,&nbsp;Mel Melewski DPT, NCS ,&nbsp;Dana Provost DPT, NCS ,&nbsp;Matthew B. Sonagere DO","doi":"10.1016/j.arrct.2025.100551","DOIUrl":"10.1016/j.arrct.2025.100551","url":null,"abstract":"<div><h3>Objective</h3><div>To determine the safety and efficacy of moderate to high intensity exercise for patients in the subacute phase of stroke recovery.</div></div><div><h3>Data Sources</h3><div>Embase, PubMed, Cochrane Central Register of Controlled Trials, CINAHL, ClinicalTrials.gov, Google Scholar, and previous meta-analyses published between January 1994 and October 2024.</div></div><div><h3>Study Selection</h3><div>Title and abstract screening required consensus by 2 reviewers. A total of 27 randomized controlled trials met inclusion criteria. Studies were included if they enrolled participants &lt;6 months post stroke. Interventions were eligible if they were of moderate or high cardiovascular intensity as defined by the American College of Sports Medicine. Acceptable comparator groups included sham, low intensity interventions, no exercise, relaxation, or cognitive interventions.</div></div><div><h3>Data Extraction</h3><div>Three reviewers independently extracted data using the COVIDENCE platform, with each article reviewed by at least 2 individuals. Random effect meta-analyses were employed to generate pooled estimates of effects. Primary outcomes included severe cardiac and cerebral adverse events, measures of endurance, and gait speed. Secondary outcomes included death, blood pressure, balance, quality of life, and functional independence.</div></div><div><h3>Data Synthesis</h3><div>Several measures of endurance and gait speed were significantly improved with moderate to high intensity interventions (change in 6-minute walk test, mean difference (MD): 33.11 m; 95% CI, 23.24-42.98; <em>P&lt;</em>.001, <em>k</em>=15; change in peak work rate, MD: 9.28 watts; 95% CI, 5.20-13.37; <em>P</em>=.002; and change in fastest gait speed, MD: 0.12 m/s; 95% CI: 0.05-0.19; <em>P</em>=.003, <em>k</em>=10). Severe adverse cardiac/cerebral events (SAE), peak volume of oxygen, comfortable gait speed, and secondary outcomes did not significantly differ between groups (SAE incidence rate ratio: 1.45; 95% CI, 0.74-2.82; <em>P</em>=.245, <em>k</em>=11).</div></div><div><h3>Conclusions</h3><div>Moderate to high intensity exercise should be considered within acute rehabilitation facilities, skilled nursing facilities, and outpatient settings for patients in the subacute phase of post stroke rehabilitation and screened as appropriate. Physician collaboration for patient selection and continued active monitoring for SAEs is recommended.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"8 1","pages":"Article 100551"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147428610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variations in Head-Neck Posture and Hyoid Kinematics in Patients With Stroke and Aspiration Risk: A Cross-Sectional Observational Study","authors":"Haipeng Jin MD ,&nbsp;Yanli Huang MS ,&nbsp;Weihong Xiao MS ,&nbsp;Li Ding MD ,&nbsp;Ling Gao MS ,&nbsp;Huijuan Zheng MS ,&nbsp;Rongrong Ye MS","doi":"10.1016/j.arrct.2025.100570","DOIUrl":"10.1016/j.arrct.2025.100570","url":null,"abstract":"<div><h3>Objective</h3><div>To observe alterations in head-neck posture and hyoid kinematics in patients with stroke and aspiration risk.</div></div><div><h3>Design</h3><div>A prospective observational study.</div></div><div><h3>Setting</h3><div>Hospital inpatient unit.</div></div><div><h3>Participants</h3><div>A total of 24 patients (N=24) with stroke were included in this study: 12 patients with high aspiration risk (7 men and 5 women) aged 62-77 years (median=72.50; IQR, 64.00-74.00) and 12 patients with low aspiration risk (8 men and 4 women) aged 50-80 years (median=66.00; IQR, 58.25-71.25).</div></div><div><h3>Interventions</h3><div>Not applicable.</div></div><div><h3>Main Outcome Measures</h3><div>Head-neck posture was assessed by craniovertebral angle (CVA), coronal C2-C7 Cobb angle, and cervical range of motion (CROM). Hyoid kinematics were evaluated via anterior horizontal displacement, superior horizontal displacement, and motion duration.</div></div><div><h3>Results</h3><div>Compared with the low aspiration risk group, the high aspiration risk group exhibited a significantly smaller CVA and reduced CROM, along with diminished hyoid displacement (<em>P</em>&lt;.05). Additionally, CROM for active extension was significantly greater than that for passive extension in the high aspiration risk group (<em>z</em>=−2.937, <em>P</em>=.003). Correlation analysis showed that there were significant positive correlations between head-neck posture (CVA and CROM for active and passive extension) and hyoid displacement (superior- horizontal displacement and anterior- horizontal displacement) (<em>P&lt;</em>.001).</div></div><div><h3>Conclusions</h3><div>This study observed variations in head-neck posture and hyoid kinematics in patients with stroke and aspiration risk and found positive correlations between them. Our results suggest that abnormal head-neck posture may be a relevant factor influencing swallowing function, and indicate new strategies and insights for patients with stroke.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"8 1","pages":"Article 100570"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147428872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Acupuncture Combined With Robotic Therapy in the Treatment of Limb Dysfunction After Stroke: A Systematic Review and Meta-Analysis","authors":"Tao Zhu MS ,&nbsp;Kaiyang Xue MS ,&nbsp;Ming Li MS ,&nbsp;Dan Yang BS ,&nbsp;Mingxi Yan MS ,&nbsp;Jin Cui PhD","doi":"10.1016/j.arrct.2025.100504","DOIUrl":"10.1016/j.arrct.2025.100504","url":null,"abstract":"<div><h3>Objective</h3><div>To conduct a meta-analysis investigating the effect of acupuncture combined with robotic therapy on limb dysfunction after a stroke.</div></div><div><h3>Data Sources</h3><div>Electronic searches of 8 databases were conducted from database establishment to September 20, 2024.</div></div><div><h3>Study Selection</h3><div>Randomized controlled trials comparing acupuncture combined with robot therapy versus monotherapy for poststroke limb dysfunction.</div></div><div><h3>Data Extraction</h3><div>Data extraction was independently performed by 2 authors, with any discrepancies resolved through discussion with a third investigator. The extracted dataset included the first author’s name, publication year, characteristics of the study population, sample size, intervention protocols, motor function scores, and other relevant outcome measures.</div></div><div><h3>Data Synthesis</h3><div>A total of 19 randomized controlled studies were included, encompassing 1353 patients, with a maximum sample size of 120 patients and a minimum sample size of 40 patients. Our findings revealed that the combined therapy group exhibited significantly higher scores on the Fugl-Meyer Assessment (FMA) for limb motor function and the Modified Barthel Index (MBI) for activities of daily living compared with the robot group: (standard mean difference [MD], 4.89; 95% CI, 2.66-7.12; <em>P</em>&lt;.001) and (MD, 7.17; 95% CI, 4.20-10.14; <em>P</em>&lt;.001), respectively. Similarly, the results indicated that the combined therapy group achieved significantly higher scores on both the FMA and MBI compared with the acupuncture-only group: (MD, 4.68, 95% CI, 3.32-6.04, <em>P</em>&lt;.001) and (MD, 11.66; 95% CI, 7.92-15.39; <em>P</em>&lt;.001), respectively. Furthermore, the FMA score was higher in the combined therapy group than in the conventional treatment group (MD, 5.98; 95% CI, 3.11-8.84; <em>P</em>&lt;.001).</div></div><div><h3>Conclusions</h3><div>Acupuncture combined with robotic therapy appears to enhance limb motor function and improve quality of life, with the clinical efficacy of this combined intervention exceeding that of either therapy administered individually. However, considering the moderate to low quality of the included studies and their frequent absence of blinding, future clinical research should focus on high-quality randomized double-blind controlled trials for validation.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"7 4","pages":"Article 100504"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145739021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional Trajectory of Childhood Stroke in the Inpatient Rehabilitation Setting","authors":"Jennifer Wu MD, PhD ,&nbsp;Deena S. Godfrey MD ,&nbsp;Patricia Orme MD ,&nbsp;Brian D. Wishart DO, MMS","doi":"10.1016/j.arrct.2025.100505","DOIUrl":"10.1016/j.arrct.2025.100505","url":null,"abstract":"<div><h3>Objective</h3><div>To examine the functional outcomes of a group of infants, children, and adolescents admitted to acute inpatient rehabilitation for neurologic impairments caused by a new childhood stroke.</div></div><div><h3>Design</h3><div>Retrospective cross-sectional cohort study.</div></div><div><h3>Setting</h3><div>A pediatric inpatient rehabilitation program in a stand-alone inpatient rehabilitation facility (IRF) located within an academic medical center.</div></div><div><h3>Participants</h3><div>A total of 91 patients (N=91) aged 6 months to 17.8 years were admitted to a pediatric inpatient rehabilitation program with a new diagnosis of childhood stroke.</div></div><div><h3>Interventions</h3><div>Standard of care pediatric inpatient rehabilitation treatment.</div></div><div><h3>Main Outcome Measures</h3><div>Change in the functional independence measure in children (WeeFIM) score across inpatient rehabilitation treatment.</div></div><div><h3>Results</h3><div>The 51 boys/39 girls/and 1 transgender patient were 9.6±5.7 years old with ischemic stroke (n=53) or hemorrhagic stroke (n=38). At admission, they had moderate-to-severe functional impairments (WeeFIM total score=46.5±25.5 points). Inpatient rehabilitation length of stay was 33.7±28.5 (range, 3-134) days. WeeFIM total score improved to 71.2±31.6 points at IRF discharge. Hemorrhagic (compared with ischemic) stroke was associated with higher rates of craniectomy (X²=4.6, <em>P</em>=.03) and older age at IRF admission (Z=1.98, <em>P</em>&lt;.05). Older age was associated with higher age-corrected WeeFIM total scores at admission (F=7.9, <em>P</em>=.0007) and discharge (F=18.1, <em>P</em>&lt;.001), but age did not affect change in WeeFIM score.</div></div><div><h3>Conclusions</h3><div>Pediatric inpatient rehabilitation results in functional improvements for new neurologic impairments caused by childhood stroke.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"7 4","pages":"Article 100505"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145739225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health-Related Quality of Life in Survivors of Stroke Post Inpatient Rehabilitation Discharged to a Home Setting","authors":"Siqi Xiang OT ,&nbsp;Bradley Smith BS ,&nbsp;Margaret A. French PT, DPT, PhD ,&nbsp;Heather A. Hayes DPT, PhD","doi":"10.1016/j.arrct.2025.100521","DOIUrl":"10.1016/j.arrct.2025.100521","url":null,"abstract":"<div><h3>Objective</h3><div>To examine if personal factors, stroke severity, social determinants of health, and functional status are associated with health-related quality of life (HRQOL) in individuals poststroke who have completed their inpatient rehabilitation facility (IRF) stay and have returned home. We hypothesized that functional status would explain a significant portion of variability in HRQOL after accounting for covariates, including personal factors, stroke severity, and metrics of social determinants of health.</div></div><div><h3>Design</h3><div>This study was a secondary analysis of data from a prospective, longitudinal cohort study.</div></div><div><h3>Setting</h3><div>The IRF to the community.</div></div><div><h3>Participants</h3><div>Individuals (N=72) poststroke (mean age ± SD, 64.1±14.4y, 58.3% men) who returned home after completing rehabilitation in an IRF.</div></div><div><h3>Interventions</h3><div>Not applicable.</div></div><div><h3>Main Outcome Measures</h3><div>The HRQOL in Stroke Patients-26 (HRQOLISP-26) was captured after individuals were discharged to the home setting.</div></div><div><h3>Results</h3><div>Functional status explained an additional 40% of the variance in HRQOLISP-26 after controlling for personal factors, stroke severity, and metrics of social determinants of health (<em>R²</em>=0.63, Δ<em>R²</em>=0.40, F=6.21, <em>p</em>&lt;.001). The specific functional measures that were significantly associated with HRQOLISP-26 were basic mobility (β=0.38, <em>p</em>=.01), applied cognition (β=0.56, <em>p</em>&lt;.001), and depression (β=−4.58, <em>p</em>=.03).</div></div><div><h3>Conclusions</h3><div>We found that functional status, including mobility, cognition, and depression, is implicated in affecting HRQOL in individuals with subacute stroke who have completed their IRF stay and have returned home. Thus, underlying the importance of rehabilitation is the consideration of not only the progression of physical and cognitive function but also mood.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"7 4","pages":"Article 100521"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145739223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electromyographic Prediction of Walking Independence in Patients With Incomplete Spinal Cord Injury","authors":"Tatsuya Sugimoto PhD ,&nbsp;Yuma Sonoda PhD ,&nbsp;Nobuhito Taniguchi M.Eng ,&nbsp;Hiroshi Kawaguchi PhD ,&nbsp;Shintaro Izumi PhD","doi":"10.1016/j.arrct.2025.100533","DOIUrl":"10.1016/j.arrct.2025.100533","url":null,"abstract":"<div><h3>Objective</h3><div>To predict walking independence in patients with incomplete cervical cord injury (ICCI) using electromyography of the trunk and lower extremity during straight-leg raising (SLR).</div></div><div><h3>Design</h3><div>Prospective cohort study. Prediction model using logistic regression.</div></div><div><h3>Setting</h3><div>Single acute-care hospital.</div></div><div><h3>Participants</h3><div>Forty patients equally split between walking dependent and walking independent groups (mean ages: 70.7±14.4 and 63.7±15.4 years; male-to-female ratios: 18:2 and 16:4; total length of stay: 31.2±20.9 and 25.7±16.5 days).</div></div><div><h3>Interventions</h3><div>Not applicable.</div></div><div><h3>Main Outcome Measures</h3><div>Trunk and lower extremity acceleration and surface electromyography data measured during nondominant SLR and basic information were used to predict the level of walking independence at discharge or transfer from the acute-care hospital.</div></div><div><h3>Results</h3><div>The results showed that the model with the lower extremity motor score (LEMS) and the root mean square (RMS) of the contralateral external oblique (EO) had the lowest Akaike information criterion of 22.24, and both were significant factors in predicting walking independence at discharge or transfer from the acute-care hospital (<em>P</em>=.019 and .034). The predictive accuracy, sensitivity, specificity, and area under the receiver operating characteristic curve were 0.875, 0.850, 0.900, and 0.975 (95% confidence interval: 0.939-1.000), respectively.</div></div><div><h3>Conclusions</h3><div>A higher LEMS and lower RMS of the contralateral EO during nondominant SLR are significant predictors of walking independence at discharge or transfer from an acute-care hospital in patients with ICCI.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"7 4","pages":"Article 100533"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145739127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective Randomized Controlled Trial of the Impact of Olfactory Training on Cognitive and Emotional Function in Individuals with Parkinson Disease","authors":"Yunxiao Dou MD ,&nbsp;Siyu Qian MM ,&nbsp;Yichen Zhao MD ,&nbsp;Yan Tan MD ,&nbsp;Yanxin Zhao MD","doi":"10.1016/j.arrct.2025.100497","DOIUrl":"10.1016/j.arrct.2025.100497","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the clinical effects of olfactory training (OT) on olfactory function and related nonmotor symptoms in patients with Parkinson disease (PD).</div></div><div><h3>Design</h3><div>Randomized controlled trial with a duration of 6 months of follow-up.</div></div><div><h3>Setting</h3><div>A tertiary hospital providing neurology rehabilitation services in China.</div></div><div><h3>Participants</h3><div>Of 81 initially recruited PD patients, 70 completed the study (N=70, 35 per group after randomization: OT group n=35, control n=35). All participants met inclusion criteria and received standard medical care. No dropouts were because of adverse effects.</div></div><div><h3>Interventions</h3><div>The intervention group received OT using a standardized protocol. The training involved daily exposure to specific odorants for 6 months. The control group did not receive OT.</div></div><div><h3>Main Outcome Measures</h3><div>Primary outcomes included changes in olfactory test scores, memory and cognition scores (assessed using neuropsychological tests), and depressive and anxiety scale scores. These were measured before and after the 6-month intervention.</div></div><div><h3>Results</h3><div>After 6 months, the intervention group exhibited significant improvements in olfactory test scores (threshold-discrimination-identification score: t=3.839, <em>P</em>&lt;.01, Cohen’s d=0.649), memory (memory quotient: t=2.597, <em>P</em>&lt;.05, Cohen’s d=0.439) and cognition scores (Mini-Mental State Examination: z=−2.791, <em>P</em>&lt;.01, rank-biserial correlation (<em>r</em>)=−0.330 and Montreal Cognitive Assessment: t=2.626, <em>P</em>&lt;.05, Cohen’s d=0.444), depressive (Hamilton Depression Scale: z=−3.601, <em>P</em>&lt;.001, <em>r</em>=−0.425 and Patient Health Questionnaire-9: z=−2.396, <em>P</em>&lt;.05, <em>r</em>=−0.29) and anxiety (Hamilton Anxiety Scale: z=−3.049, <em>P</em>&lt;.01, <em>r</em>=−0.36 and Generalized Anxiety Disorder-7: z=−2.849, <em>P</em>&lt;.01, <em>r</em>=0.336) scale scores compared to the control group, showing moderate effects, respectively. The increase in memory scale scores was positively correlated with the increase in olfactory scores (Spearman <em>r</em>=0.415, <em>P</em>&lt;.05). Statistical analysis was performed using SPSS 27.0 software, with <em>P</em> values indicating significance.</div></div><div><h3>Conclusions</h3><div>The OT has beneficial effects on olfactory function and related nonmotor symptoms in patients with PD. The 6-month training led to significant improvements in memory, cognition, depression, and anxiety. Further studies are needed to determine the long-term effects and optimal duration of OT for patients with PD.</div></div>","PeriodicalId":72291,"journal":{"name":"Archives of rehabilitation research and clinical translation","volume":"7 4","pages":"Article 100497"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145738923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}