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Improving End-to-End Traceability and Pharma Supply Chain Resilience using Blockchain. 使用区块链提高端到端可追溯性和制药供应链弹性。
Pub Date : 2022-01-01 DOI: 10.30953/bhty.v5.231
Corrine Sim, Haisheng Zhang, Marianne Louise Chang

Regulating and monitoring a traditionally fragmented pharma supply chain has been a global challenge for decades. Without a trusted system and strong collaboration between stakeholders, threats such as counterfeits can easily intercept the supply chain and cause monumental disruptions. Today, the COVID-19 pandemic has accelerated the need for greater data transparency, better deployment of technology, and improved ways of connecting stakeholder information along the supply chain. There is a need for improved ways of working to help build up supply chain resilience, and one way is by implementing better end-to-end traceability using blockchain technology such as Hyperledger Fabric. This paper will explore the business value that blockchain brings to the pharma supply chain with better end-to-end traceability, using the example of an industry-grade blockchain solution called eZTracker. Through six key features, pharmaceutical manufacturers, patients, and Healthcare Practitioners (HCPs) can now participate in data sharing, with extended use cases of integrating blockchain with warehouse platforms, a patient-facing mobile application, and an interactive dashboard for real-time verification and data transparency. Beyond anti-counterfeit verification, other potential use cases include effective product recall management, cold chain monitoring, e-product information, and more. The effectiveness of a traceability solution is heavily dependent on the amount of data collected and is affected by poor adoption and scalability. Existing limitations that need to be addressed include the lack of mandated serialization in Asia and blockchain interoperability. To maximize the value of blockchain, collaboration is the key. Pharmaceutical manufacturers need to invest in new technologies, such as blockchain, to help them break out of data silos and operationalize data to build supply chain resilience. Pharmaceutical supply chain is the backbone of a US$1.27 trillion industry,1 but because of its highly complex and fragmented nature, it is hard to regulate and protect, and this makes it a valuable target for opportunistic parties such as counterfeiters looking to profit.2 As a result of the COVID-19 pandemic, there has been greater emphasis on transparency of data and connecting stakeholders along the pharma supply chain in real-time in the last few years. With the introduction of blockchain technology, companies are now able to implement solutions with more effective track and trace results, providing quality assurance to pharmaceutical manufacturers, patients, and Healthcare Practitioners (HCPs), and even improving operational efficiencies. This paper seeks to explore the positive business impact of end-to-end traceability using blockchain technology, and the effects it brings about, such as improving supply chain resilience and combating counterfeits, as seen in successful live use cases in Asia.

几十年来,管理和监测传统上分散的制药供应链一直是一项全球性挑战。如果没有可信的系统和利益相关者之间的强有力合作,假冒等威胁很容易拦截供应链并造成巨大的破坏。今天,COVID-19大流行加速了对提高数据透明度、更好地部署技术和改进供应链中利益攸关方信息联系方式的需求。需要改进工作方式来帮助建立供应链弹性,其中一种方法是使用Hyperledger Fabric等区块链技术实现更好的端到端可追溯性。本文将以一个名为eZTracker的工业级区块链解决方案为例,探讨区块链为制药供应链带来的更好的端到端可追溯性的商业价值。通过六个关键功能,制药商、患者和医疗从业者(HCPs)现在可以参与数据共享,扩展用例将区块链与仓库平台、面向患者的移动应用程序以及用于实时验证和数据透明度的交互式仪表板集成在一起。除了防伪验证,其他潜在的用例还包括有效的产品召回管理、冷链监控、电子产品信息等。可追溯性解决方案的有效性在很大程度上依赖于收集的数据量,并受到不良采用和可伸缩性的影响。需要解决的现有限制包括亚洲缺乏强制序列化和区块链互操作性。要使区块链的价值最大化,协作是关键。制药商需要投资于区块链等新技术,以帮助他们打破数据孤岛,并对数据进行操作,以建立供应链弹性。药品供应链是1.27万亿美元行业的支柱1,但由于其高度复杂和分散的性质,难以监管和保护,这使其成为寻求获利的投机分子(如造假者)的宝贵目标2由于2019冠状病毒病大流行,在过去几年中,人们更加强调数据的透明度,并实时连接制药供应链上的利益相关者。随着区块链技术的引入,公司现在能够实施具有更有效跟踪和跟踪结果的解决方案,为制药商、患者和医疗保健从业者(HCPs)提供质量保证,甚至提高运营效率。本文旨在探索使用区块链技术的端到端可追溯性的积极商业影响,以及它带来的影响,例如提高供应链弹性和打击假冒,正如亚洲成功的现场用例所示。
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引用次数: 5
2 Decentralized applications 2去中心化应用
Pub Date : 2021-11-08 DOI: 10.1515/9783110681130-002
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引用次数: 0
Frontmatter
Pub Date : 2021-11-08 DOI: 10.1515/9783110681130-fm
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引用次数: 0
List of notions 概念清单
Pub Date : 2021-11-08 DOI: 10.1515/9783110681130-204
Ledger A book, a list, or other collection of financial accounts and/or transactions. % Attack A potential attack on a blockchain network, where a single entity or organization is able to control the majority of the hash power, potentially causing a network disruption. In such a scenario, the attacker would have enough mining power to intentionally exclude or modify the ordering of transactions. -blocks Confirmation A period of time (commonly around  min) necessary for adding six new blocks behind a solved block that contain some transaction. After this period, the transaction is considered confirmed because creating a new version of the blockchain that will not contain a given transaction becomes too difficult, because too expensive in computing power. Altcoins Cryptocurrencies other than Bitcoin. Artificial Neural Networks A computing system is based on a collection of connected units or nodes called artificial neurons, which loosely model the neurons in a biological brain. Bitcoin The most popular cryptocurrency, running on a blockchain created in January  by an unknown person under the pseudonym Satoshi Nakamoto. Bitcoin/Digital Wallet A software program for holding and trading Bitcoins which uses a person’s private key (secret number) to access the person’s public Bitcoin address (an identifier of – alphanumeric characters) and transaction signatures that need to be securely stored; the Bitcoin wallet comes in many forms – the four main types are desktop, mobile, web, and hardware. Blockchain A distributed ledger consists of a series of transaction blocks where each block (except the first and the last) is linked with the previous and next block by means of cryptography, making that way an unbreakable chain of blocks. Blockchain Fork A situation within the community (of nodes/members of a blockchain PP network) that occurs when in the network exist two or more versions of the blockchain (i.e., different nodes may have different versions of the file which contains blockchain data). Blockchain Mining A peer-to-peer computer process aimed to secure and verify transactions of a given cryptocurrency (such as Bitcoin). Border Gateway Protocol Protocol for routing of IP packets (routing protocol); it is a standardized exterior gateway protocol designed to exchange routing and reachability information among autonomous systems on the Internet. Branch Tip A tip that represents the last individual transaction in a branch tip bundle (see IOTA bundle).
分类账财务帐目和/或交易的帐簿、清单或其他集合。%攻击对区块链网络的潜在攻击,其中单个实体或组织能够控制大部分哈希算力,可能导致网络中断。在这种情况下,攻击者将有足够的挖掘能力故意排除或修改事务的顺序。-blocks Confirmation需要一段时间(通常在min左右),以便在包含一些交易的已解决块后面添加六个新块。在这段时间之后,交易被认为是确认的,因为创建一个不包含给定交易的区块链新版本变得太困难,因为计算能力太昂贵。山寨币比特币以外的加密货币。人工神经网络计算系统是基于一组被称为人工神经元的连接单元或节点的集合,这些单元或节点松散地模拟了生物大脑中的神经元。比特币:最受欢迎的加密货币,运行在一月创建的区块链上由一个化名中本聪的不知名人士创建。比特币/数字钱包一种用于持有和交易比特币的软件程序,它使用一个人的私钥(秘密号码)来访问该人的公共比特币地址(一个标识符-字母数字字符)和需要安全存储的交易签名;比特币钱包有多种形式——四种主要类型是桌面、移动、网络和硬件。分布式账本由一系列交易块组成,其中每个块(除了第一个和最后一个)通过加密技术与前一个和下一个块链接,从而形成一个牢不可破的块链。区块链分叉在社区(区块链P网络的节点/成员)中发生的一种情况,当网络中存在两个或多个版本的区块链时(即,不同的节点可能具有包含区块链数据的文件的不同版本)。一种点对点的计算机过程,旨在保护和验证给定加密货币(如比特币)的交易。边界网关协议IP包的路由协议(路由协议);它是一种标准化的外部网关协议,用于在Internet上的自治系统之间交换路由和可达性信息。分支提示表示分支提示包中最后一个单独事务的提示(参见IOTA bundle)。
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引用次数: 0
4 Selected use cases 4选定的用例
Pub Date : 2021-11-08 DOI: 10.1515/9783110681130-004
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引用次数: 0
1 Distributed ledger technologies 1分布式账本技术
Pub Date : 2021-11-08 DOI: 10.1515/9783110681130-001
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引用次数: 0
3 Distributed ledgers and internet of things 3 .分布式账本和物联网
Pub Date : 2021-11-08 DOI: 10.1515/9783110681130-003
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引用次数: 0
Blockchain + Local Government Innovation 区块链+地方政府创新
Pub Date : 2021-07-16 DOI: 10.1142/9789811236518_0005
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引用次数: 0
Application Cases of Blockchain Combined with Real Industry 区块链与实体产业结合的应用案例
Pub Date : 2021-07-16 DOI: 10.1142/9789811236518_0007
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引用次数: 0
Blockchain Technology Architecture and Development Trends 区块链技术架构与发展趋势
Pub Date : 2021-07-16 DOI: 10.1142/9789811236518_0002
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引用次数: 0
期刊
Blockchain in healthcare today
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