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[Multimorbidity in liver surgery]. [肝脏手术中的多病]。
Pub Date : 2025-01-08 DOI: 10.1007/s00104-024-02222-7
Emrullah Birgin, Jan Heil, Elisabeth Miller, Marko Kornmann, Nuh N Rahbari

Multimorbidity is characterized by the presence of at least 3 chronic diseases with a prevalence of more than 50% of patients over 60 years old. The Charlson comorbidity index (CCI) enables a description of the severity of the multimorbidity and also provides a correlation with the postoperative outcome after liver resection. According to this, multimorbid patients are at increased risk of morbidity and mortality after liver resection, mostly due to postoperative liver failure. In particular, open major liver resection with biliary reconstruction and primary liver tumors linked to metabolic associated fatty liver disease (MAFLD) pose an increased risk for multimorbid patients. In contrast, minimally invasive resection leads to a clear reduction in postoperative morbidity and mortality. Preconditioning of the liver and the implementation of perioperative strategies according to the enhanced recovery after surgery (ERAS) concept can also lead to an improvement of the postoperative outcome.

多病的特点是存在至少3种慢性疾病,60岁以上患者的患病率超过50%。Charlson合并症指数(CCI)能够描述多重疾病的严重程度,也提供了与肝切除术后的术后结果的相关性。由此可见,多病患者在肝切除术后发病和死亡的风险增加,主要是由于术后肝功能衰竭。特别是,开放大肝切除术合并胆道重建和与代谢性脂肪性肝病(MAFLD)相关的原发性肝脏肿瘤会增加多病患者的风险。相比之下,微创切除可明显降低术后发病率和死亡率。根据术后增强恢复(ERAS)概念对肝脏进行预处理和围手术期策略的实施也可以改善术后结果。
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引用次数: 0
[The multimorbid patient-Risk stratification and indications in pancreatic surgery]. 胰腺手术的多病患者风险分层和适应症。
Pub Date : 2025-01-06 DOI: 10.1007/s00104-024-02223-6
Islam Labib, Jürgen Weitz, Sebastian Hempel

Background: Pancreatic surgery is still associated with significant morbidity. In a simultaneously increasingly ageing population with elevated morbidity, the risk stratification and indications for surgery are of particular importance.

Objective: Assessment of the impact of multimorbidity of patients on the postoperative outcome after pancreatic surgery.

Material and methods: Evaluation and summary of the available literature.

Results: The postoperative morbidity after pancreatic surgery remains high. Relevant comorbidities, such as liver cirrhosis, cardiac and pulmonary diseases and advanced renal insufficiency enormously increase the risk of perioperative morbidity and mortality; however, in high-volume centers with appropriate expertise in pancreatic surgery the mortality is below 5%.

Conclusion: Pancreatic surgery with severe comorbidity can be safely performed in centers with proven expertise. Nevertheless, a careful interpretation of the indications and good patient selection are essential for the postoperative outcome.

背景:胰腺手术仍然与显著的发病率相关。在人口老龄化和发病率升高的同时,风险分层和手术指征尤为重要。目的:探讨胰腺手术患者多病对术后预后的影响。材料和方法:对现有文献进行评价和总结。结果:胰腺手术术后发病率居高不下。相关合并症,如肝硬化、心肺疾病和晚期肾功能不全,极大地增加了围手术期发病率和死亡率的风险;然而,在具有适当胰腺手术专业知识的大容量中心,死亡率低于5%。结论:有严重合并症的胰腺手术可以在有经验的中心安全地进行。然而,仔细解释适应症和良好的患者选择对术后结果至关重要。
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引用次数: 0
[Cost comparison of conservative vs. surgical treatment of chronic lymphedema]. [慢性淋巴水肿保守治疗与手术治疗的成本比较]。
Pub Date : 2025-01-01 Epub Date: 2024-06-28 DOI: 10.1007/s00104-024-02123-9
Rima Nuwayhid, Stefan Langer, Nikolaus von Dercks

Background: Lymphedema is primarily treated conservatively using complex physical decongestion treatment (CDT). Lymphovenous anastomosis (LVA), vascularized lymph node transplantation (VLNT) and liposuction are available as surgical treatment methods; however, reimbursement in the diagnosis-related groups (DRG) system is sometimes inadequate or only possible following an individual application. The costs of these relatively new surgical procedures have not yet been set in relation to those of CDT.

Method: The costs of conservative treatment were determined in accordance with the guidelines. The costs for LVA, VLNT and liposuction of the upper and lower extremities were estimated on the basis of the DRG reimbursement per case and the expected reduction in conservative measures according to current knowledge. The annual treatment costs were then compared.

Results: The annual treatment costs of LVA and VLNT are already lower than conservative treatment alone in the second postoperative year. Liposuction reaches this point in the 6th (upper extremity) or 47th postoperative year (lower extremity).

Conclusion: The evidence for the positive effects of lymphatic surgery is still limited; however, it is recognizable that the curative surgical approach can significantly reduce the treatment costs and improve the quality of life of lymphedema patients; however, there is a lack of adequate reflection of the surgical effort in the reimbursement.

背景:淋巴水肿主要采用复合物理去充血疗法(CDT)进行保守治疗。淋巴管吻合术(LVA)、血管化淋巴结移植术(VLNT)和抽脂术可作为外科治疗方法;然而,诊断相关组别(DRG)系统的报销有时并不充分,或只能在个人申请后才能报销。这些相对较新的外科手术的费用尚未与 CDT 的费用相比较:方法:根据指南确定保守治疗的费用。方法:根据指南确定了保守治疗的费用,并根据 DRG 每例报销额度和当前知识对保守治疗的预期减少额度估算了 LVA、VLNT 和上下肢吸脂术的费用。然后对每年的治疗费用进行了比较:结果:在术后第二年,LVA 和 VLNT 的年度治疗费用已经低于单纯的保守治疗。吸脂术在术后第 6 年(上肢)或第 47 年(下肢)达到这一水平:淋巴手术积极效果的证据仍然有限;不过,治疗性手术方法可以显著降低淋巴水肿患者的治疗费用并改善其生活质量,这一点已得到认可;然而,在报销方面却没有充分反映手术的效果。
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引用次数: 0
[Conversion therapies for initially unresectable hepatocellular carcinoma]. [最初不可切除的肝细胞癌的转化治疗]。
Pub Date : 2025-01-01 Epub Date: 2024-12-02 DOI: 10.1007/s00104-024-02207-6
J Fritsch, M Ardelt, U Settmacher
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引用次数: 0
[New digital assistive systems: potential in visceral medicine]. [新的数字辅助系统:内脏医学的潜力]。
Pub Date : 2025-01-01 Epub Date: 2025-01-13 DOI: 10.1007/s00104-024-02220-9
Dirk Weyhe
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引用次数: 0
[The "oncological risks" of organ preservation in rectal cancer: results from two international registries]. [直肠癌器官保存的“肿瘤学风险”:来自两个国际登记处的结果]。
Pub Date : 2025-01-01 Epub Date: 2024-12-05 DOI: 10.1007/s00104-024-02206-7
C T Germer, J Reibetanz
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引用次数: 0
[From imaging to interaction with 3D models: technical aspects]. [从成像到与3D模型的交互:技术方面]。
Pub Date : 2025-01-01 Epub Date: 2024-12-23 DOI: 10.1007/s00104-024-02214-7
Andrea Schenk, Alexander Kluge, Sirko Pelzl, Gabriel Zachmann, Rainer Malaka

Augmented and virtual reality (AR and VR, respectively) are already being used or evaluated in some medical fields: however, the widespread application is still hampered by inconsistent and often confusing terminology, in particular for people who are not familiar with current developments. Additionally, the technical principles and requirements for its use are often insufficiently well known. This overview article therefore aims to clarify the most important terminology and presents the current technical state of the art, spanning from the requirements of medical imaging, through 3D models and the various forms of visualization to the interaction possibilities within VR and AR. This should help to facilitate a common language among developers and users and to ensure that the potentials offered by digital assistive technologies can be fully exploited in the future.

增强现实和虚拟现实(分别为AR和VR)已经在一些医疗领域得到使用或评估:然而,广泛应用仍然受到不一致和经常令人困惑的术语的阻碍,特别是对于不熟悉当前发展的人来说。此外,其使用的技术原则和要求往往不够为人所知。因此,这篇综述文章旨在澄清最重要的术语,并展示当前的技术状态,从医学成像的要求,到3D模型和各种形式的可视化,再到VR和AR中的交互可能性。这应该有助于促进开发人员和用户之间的共同语言,并确保数字辅助技术提供的潜力在未来可以得到充分利用。
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引用次数: 0
[Augmented and virtual reality in surgery: fields of application and exploratory studies exemplified by VIVATOP : Perioperative surgical planning and intraoperative support]. [增强和虚拟现实在手术中的应用:以VIVATOP为例的应用领域和探索性研究:围手术期手术计划和术中支持]。
Pub Date : 2025-01-01 Epub Date: 2025-01-03 DOI: 10.1007/s00104-024-02218-3
Dirk Weyhe, Verena Hartmann, Verena Uslar, Navid Tabriz

Digital technologies, such as virtual and augmented reality (VR and AR) are mainly used in the preclinical and clinical phases in neurosurgery and orthopedics. In contrast, they are used less frequently in visceral surgery as the intraoperative deformation is challenging for the clinical use. The application of VR is used successfully particularly in education and training. In addition to current areas of application, this article highlights the results of the Federal Ministry of Education and Research (BMBF) project "Versatile Immersive Virtual and Augmented Tangible OP (= surgery)" (VIVATOP). In this project AR and VR technologies in combination with 3D printing as demonstrators were newly or further developed. A VR planning tool for partial liver resection, the development of 3D holograms for intraoperative AR support and an avatar telemedicine function as well as a 3D printed model for training purposes were developed. The clinical results of the intraoperative AR support with the primary endpoint of operation duration and the secondary endpoints of the duration of hospitalization and intensive care unit stay as well as complication rates are compared with a historical cohort and the results are contextualized.

虚拟现实和增强现实(VR和AR)等数字技术主要应用于神经外科和骨科的临床前和临床阶段。相比之下,它们较少用于内脏手术,因为术中变形对临床应用具有挑战性。虚拟现实技术在教育培训领域的应用尤为成功。除了当前的应用领域外,本文还重点介绍了联邦教育和研究部(BMBF)项目“多功能沉浸式虚拟和增强有形OP(=手术)”的结果。(VIVATOP)。在这个项目中,AR和VR技术与3D打印技术相结合,作为新的或进一步发展的示范。开发了用于部分肝脏切除的VR规划工具、用于术中AR支持的3D全息图开发、虚拟化身远程医疗功能以及用于培训目的的3D打印模型。术中AR支持的临床结果以手术时间为主要终点,以住院时间和重症监护病房时间为次要终点,以及并发症发生率为次要终点,与历史队列进行比较,并对结果进行背景分析。
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引用次数: 0
[Rare complication of a parastomal hernia in a patient with an ileal conduit]. [回肠导管患者罕见的吻合口旁疝并发症]。
Pub Date : 2025-01-01 Epub Date: 2024-09-05 DOI: 10.1007/s00104-024-02169-9
C Benignus, H Griesemann, A Merscher, C Marquardt, S Retter, T Schiedeck
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引用次数: 0
[Virtual reality in liver surgery-Planning, advanced training, testing]. [肝脏手术中的虚拟现实-计划,高级培训,测试]。
Pub Date : 2025-01-01 Epub Date: 2024-12-17 DOI: 10.1007/s00104-024-02216-5
Tobias Huber, Florentine Huettl, Lukas Vradelis, Verena Tripke, Danny Schott, Vuthea Chheang, Patrick Saalfeld, Mareen Allgaier, Sylvia Saalfeld, Bernhard Preim, Christian Hansen, Laura Isabel Hanke, Hauke Lang

Anatomical structures of the liver could be reconstructed three dimensionally from preoperative cross-sectional imaging for over 20 years. This three-dimensional (3D) representation not only optimizes the preoperative planning options but also the communication of specific operation-relevant structures can be improved using 3D models. In addition to a plastic and interactive visualization of 3D organ models, the disruptive technology of virtual reality (VR) can also provide a possibility for structured training and further education regarding surgical anatomy of the liver and operation planning. This makes examinations in virtual reality also seem tangible. The latest prototypes even enable patient-specific simulation of intraoperative sonography. This review article provides an overview of the current status of available technologies for training and further education using VR exemplified by liver surgery.

在过去的20多年里,肝脏的解剖结构可以从术前的横断成像中三维重建。这种三维(3D)表示不仅优化了术前计划选择,而且可以使用3D模型改善具体操作相关结构的沟通。除了3D器官模型的塑性和交互式可视化外,虚拟现实(VR)的颠覆性技术还可以提供关于肝脏外科解剖和手术计划的结构化培训和继续教育的可能性。这使得虚拟现实中的考试也变得有形。最新的原型机甚至可以实现针对患者的术中超声模拟。本文综述了以肝脏手术为例的VR培训和继续教育的现有技术现状。
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Chirurgie (Heidelberg, Germany)
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