Pub Date : 2023-06-01DOI: 10.56397/crms.2023.06.08
Shan-shan Chen, Yingjie Sun, Jianxing Liu, W. Yan, Jiakun Liu, Wenjun Hu
Androgenetic alopecia (AGA) is the most common type of hair loss, in which patients mostly present with a state of a receding hairline on the forehead. It brings a great mental burden to the patient. Androgenetic alopecia is caused by the combination of dihydrotestosterone (DHT) and androgen receptors (AR), disrupting the hair follicle cycle and minimizing hair follicles. The major treatments currently available include finasteride, minoxidil, hair transplantation, Platelet-rich plasma (PRP), stem cell therapy, etc. This article reviews the mechanism of AGA and the existing major treatments. The author suggested that androgen receptor degrader drugs have good prospects for application among those of various therapeutic options.
{"title":"The Progress of Common Treatments and Research for Androgenetic Alopecia","authors":"Shan-shan Chen, Yingjie Sun, Jianxing Liu, W. Yan, Jiakun Liu, Wenjun Hu","doi":"10.56397/crms.2023.06.08","DOIUrl":"https://doi.org/10.56397/crms.2023.06.08","url":null,"abstract":"Androgenetic alopecia (AGA) is the most common type of hair loss, in which patients mostly present with a state of a receding hairline on the forehead. It brings a great mental burden to the patient. Androgenetic alopecia is caused by the combination of dihydrotestosterone (DHT) and androgen receptors (AR), disrupting the hair follicle cycle and minimizing hair follicles. The major treatments currently available include finasteride, minoxidil, hair transplantation, Platelet-rich plasma (PRP), stem cell therapy, etc. This article reviews the mechanism of AGA and the existing major treatments. The author suggested that androgen receptor degrader drugs have good prospects for application among those of various therapeutic options.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80957416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.56397/crms.2023.06.10
R. Ayyad, A. Nejm, Ahmed R. Ayyad
The human body has the heart, which is Levo, and the gastrointestinal tract, with the liver in the Dextro position. The carbohydrates in our food are Dextro, and the amino acids in our food are Levo; hence, the isomers of compounds taken by humans may be harmful or ineffective. As a result, we will investigate some drugs in which one of its isomers is effective while the other is ineffective, such as Levo and Dextro-Ethambutol, Levo and Dextro-Dopa, Levo and Dextro-Amphetamine, Dextro and Levo-Rabeprazole, Cis and Trans-Platin, R and S-Hexobarbital, R and S-Fluoxetine. It may be that each isomer has one pharmacological difference from the other isomer, e.g., quinine and quinidine, and R and S-propafenone.
{"title":"The Isomers of Some Drugs One Effective and the Other Is Toxic or Ineffective","authors":"R. Ayyad, A. Nejm, Ahmed R. Ayyad","doi":"10.56397/crms.2023.06.10","DOIUrl":"https://doi.org/10.56397/crms.2023.06.10","url":null,"abstract":"The human body has the heart, which is Levo, and the gastrointestinal tract, with the liver in the Dextro position. The carbohydrates in our food are Dextro, and the amino acids in our food are Levo; hence, the isomers of compounds taken by humans may be harmful or ineffective. As a result, we will investigate some drugs in which one of its isomers is effective while the other is ineffective, such as Levo and Dextro-Ethambutol, Levo and Dextro-Dopa, Levo and Dextro-Amphetamine, Dextro and Levo-Rabeprazole, Cis and Trans-Platin, R and S-Hexobarbital, R and S-Fluoxetine. It may be that each isomer has one pharmacological difference from the other isomer, e.g., quinine and quinidine, and R and S-propafenone.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"147 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86650795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.56397/crms.2023.03.05
S. Jargin
This mini-review analyzes medical and psychological aspects of the conflict in Ukraine. If the global power shifts to Russia, it may come along with losses of certain values. The quality of many services, products and foodstuffs will decline. Autocratic or military management style will gain sway also in the healthcare and science. Attributes of this style include the lack of criticism and objective discussion, paternalistic approach to patients, bossy management and occasional disregard of the principle of informed consent. Suboptimal practices have been used as per instructions and leading experts’ publications. To name but a few: the overuse of Halsted and Patey mastectomy with excision of pectoral muscles, coagulation of endocervical ectopies without cyto- or histological check for precancerous changes, parabulbar injections of placebos, extensive gastric resections for peptic ulcers, thoracic and abdominal surgery for bronchial asthma and diabetes mellitus, overuse of surgery in tuberculosis. Psychological issues related to the Ukraine conflict are discussed here. Repressed shame may cause aggression. Some topics discussed in this article are associated with shame, summarily reflected by the comparatively low life expectancy and world highest abortion rate in Russia. Instead of machismo and militarism, the propaganda should popularize the image of scrupulous and hardworking people.
{"title":"The Conflict in Ukraine: Medical and Psychological Aspects","authors":"S. Jargin","doi":"10.56397/crms.2023.03.05","DOIUrl":"https://doi.org/10.56397/crms.2023.03.05","url":null,"abstract":"This mini-review analyzes medical and psychological aspects of the conflict in Ukraine. If the global power shifts to Russia, it may come along with losses of certain values. The quality of many services, products and foodstuffs will decline. Autocratic or military management style will gain sway also in the healthcare and science. Attributes of this style include the lack of criticism and objective discussion, paternalistic approach to patients, bossy management and occasional disregard of the principle of informed consent. Suboptimal practices have been used as per instructions and leading experts’ publications. To name but a few: the overuse of Halsted and Patey mastectomy with excision of pectoral muscles, coagulation of endocervical ectopies without cyto- or histological check for precancerous changes, parabulbar injections of placebos, extensive gastric resections for peptic ulcers, thoracic and abdominal surgery for bronchial asthma and diabetes mellitus, overuse of surgery in tuberculosis. Psychological issues related to the Ukraine conflict are discussed here. Repressed shame may cause aggression. Some topics discussed in this article are associated with shame, summarily reflected by the comparatively low life expectancy and world highest abortion rate in Russia. Instead of machismo and militarism, the propaganda should popularize the image of scrupulous and hardworking people.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91221640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.56397/crms.2023.03.01
Igor Klepikov
The reasons for the misconceptions that have arisen in modern ideas about the features of acute nonspecific inflammation of the lung tissue and the direction of the necessary correction are considered.
对现代观念中出现的关于肺组织急性非特异性炎症特征的误解的原因和必要的纠正方向进行了考虑。
{"title":"Can Modern Medicine Have Distorted Ideas?","authors":"Igor Klepikov","doi":"10.56397/crms.2023.03.01","DOIUrl":"https://doi.org/10.56397/crms.2023.03.01","url":null,"abstract":"The reasons for the misconceptions that have arisen in modern ideas about the features of acute nonspecific inflammation of the lung tissue and the direction of the necessary correction are considered.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136245929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.56397/crms.2023.03.03
Yujuan Yan, Yingchun Tai, Hua-yuan Yang, Mengmeng Wang
In this paper, by analyzing a large number of domestic and foreign literatures on the treatment of postpartum depression in recent years, the research progress of traditional Chinese medicine (TCM) in the treatment of postpartum depression was systematically reviewed. Sum up after a postpartum depression of the most common etiology and pathogenesis, from the compound Chinese medicine, acupuncture, needle medicine use, massage, music therapy and traditional Chinese medicine fumigation treatment, according to the basic theory of TCM in detail its historical source, choose party on the basis of TCM syndrome differentiation, acupuncture and moxibustion therapy in a variety of acupuncture and moxibustion treatment of forms, and other characteristics of traditional Chinese medicine therapy. Literature review shows that: The doctor of traditional Chinese medicine in the treatment of postpartum depression, with overall concept as guiding ideology, thus improve the systemic symptom of patients, improve the quality of life, and there are diversified TCM therapies, patients and their families have high acceptance, small side effects, make up the deficiency of western medicine, not only in the clinical practice to improve the curative effect of treatment of postpartum depression, also for the general medical compatriots to broaden the diagnosis and treatment method of postpartum depression, provide evidence for the selection of treatment for such patients.
{"title":"Research Progress in Diagnosis and Treatment of Postpartum Depression by Traditional Chinese Medicine","authors":"Yujuan Yan, Yingchun Tai, Hua-yuan Yang, Mengmeng Wang","doi":"10.56397/crms.2023.03.03","DOIUrl":"https://doi.org/10.56397/crms.2023.03.03","url":null,"abstract":"In this paper, by analyzing a large number of domestic and foreign literatures on the treatment of postpartum depression in recent years, the research progress of traditional Chinese medicine (TCM) in the treatment of postpartum depression was systematically reviewed. Sum up after a postpartum depression of the most common etiology and pathogenesis, from the compound Chinese medicine, acupuncture, needle medicine use, massage, music therapy and traditional Chinese medicine fumigation treatment, according to the basic theory of TCM in detail its historical source, choose party on the basis of TCM syndrome differentiation, acupuncture and moxibustion therapy in a variety of acupuncture and moxibustion treatment of forms, and other characteristics of traditional Chinese medicine therapy. Literature review shows that: The doctor of traditional Chinese medicine in the treatment of postpartum depression, with overall concept as guiding ideology, thus improve the systemic symptom of patients, improve the quality of life, and there are diversified TCM therapies, patients and their families have high acceptance, small side effects, make up the deficiency of western medicine, not only in the clinical practice to improve the curative effect of treatment of postpartum depression, also for the general medical compatriots to broaden the diagnosis and treatment method of postpartum depression, provide evidence for the selection of treatment for such patients.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83855988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.56397/crms.2023.03.06
C. Feng, Bruce Song, Xiyang Peng
The Hippo pathway is an important pathway to control cell proliferation and organ size. By sensing extracellular matrix stiffness and intercellular mechanical force and converting them into molecular signal transduction, through a series of cascade amplification effects of kinases, the final the phosphorylation of YAP/TAZ, the main downstream target of the Hippo pathway, plays a series of regulatory roles. Although many studies have shown that Hippo signaling changes during skeletal muscle hypertrophy, the complex mechanism of Hippo signaling in skeletal muscle hypertrophy remains to be further studied. In this review, we summarize the relationship between Hippo-YAP/TAZ signaling and skeletal muscle hypertrophy and sort out the contribution of the main factors in the process of skeletal muscle hypertrophy.
{"title":"Research Progress of Hippo-Yap/Taz Signaling in Skeletal Muscle Hypertrophy","authors":"C. Feng, Bruce Song, Xiyang Peng","doi":"10.56397/crms.2023.03.06","DOIUrl":"https://doi.org/10.56397/crms.2023.03.06","url":null,"abstract":"The Hippo pathway is an important pathway to control cell proliferation and organ size. By sensing extracellular matrix stiffness and intercellular mechanical force and converting them into molecular signal transduction, through a series of cascade amplification effects of kinases, the final the phosphorylation of YAP/TAZ, the main downstream target of the Hippo pathway, plays a series of regulatory roles. Although many studies have shown that Hippo signaling changes during skeletal muscle hypertrophy, the complex mechanism of Hippo signaling in skeletal muscle hypertrophy remains to be further studied. In this review, we summarize the relationship between Hippo-YAP/TAZ signaling and skeletal muscle hypertrophy and sort out the contribution of the main factors in the process of skeletal muscle hypertrophy.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"123 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86061219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.56397/crms.2023.03.04
Minghui Sun, Yuewei Li, Shibo Zhao
Rheumatic Heart Disease (RHD), abbreviated as rheumatic heart disease, is a heart disease caused by repeated attacks or further deterioration of Acute Rheumatic Fever (ARF), which is mostly caused by valve damage (Zhang P & Wang P., 2021). The production of ARF is the result of a series of autoimmune reactions by group A streptococci that invade the pharynx of a susceptible host. Clinically, rheumatic heart disease mostly involves valves, which can cause patients to have a variety of manifestations such as incomplete valve closure or stenosis, structural remodeling of the heart, etc. If patients do not seek medical attention in time to delay the best time for treatment, they often develop acute heart failure, malignant arrhythmias and other acute complications of the cardiovascular system in the later stages of the disease. Clinically, rheumatic heart disease complicated by infective endocarditis is not common, and valve leaflet perforation due to severe infection is even rarer! A case of acute infective endocarditis complicated by atypical rheumatic heart disease and simultaneous valve leaflet perforation in our hospital is reviewed and reported below.
{"title":"A Case of Rheumatic Heart Disease Complicated by Acute Infective Endocarditis and Valve Leaflet Perforation","authors":"Minghui Sun, Yuewei Li, Shibo Zhao","doi":"10.56397/crms.2023.03.04","DOIUrl":"https://doi.org/10.56397/crms.2023.03.04","url":null,"abstract":"Rheumatic Heart Disease (RHD), abbreviated as rheumatic heart disease, is a heart disease caused by repeated attacks or further deterioration of Acute Rheumatic Fever (ARF), which is mostly caused by valve damage (Zhang P & Wang P., 2021). The production of ARF is the result of a series of autoimmune reactions by group A streptococci that invade the pharynx of a susceptible host. Clinically, rheumatic heart disease mostly involves valves, which can cause patients to have a variety of manifestations such as incomplete valve closure or stenosis, structural remodeling of the heart, etc. If patients do not seek medical attention in time to delay the best time for treatment, they often develop acute heart failure, malignant arrhythmias and other acute complications of the cardiovascular system in the later stages of the disease. Clinically, rheumatic heart disease complicated by infective endocarditis is not common, and valve leaflet perforation due to severe infection is even rarer! A case of acute infective endocarditis complicated by atypical rheumatic heart disease and simultaneous valve leaflet perforation in our hospital is reviewed and reported below.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72749551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.56397/crms.2023.03.11
Anu Bajaj
Colloid carcinoma pancreas is an infiltrative ductal epithelial neoplasm of pancreas characteristically denominating a preponderant (>80%) component of enlarged pools of extracellular stromal mucin pervaded with suspended neoplastic cells. Colloid carcinoma pancreas is a microsatellite stable tumefaction and exhibits KRAS genetic mutation confined to codon 12. Tumefaction is posited to arise from inverse polarization of cells with stromal mucin glycoproteins facing intrinsic cellular surface. Cogent clinical symptoms as abdominal or epigastric pain, pancreatitis, diarrhoea, hyperbilirubinemia or loss of weight are discerned. Tumefaction emerges as an enlarged, well demarcated lesion with a mean diameter of 5 centimetres and a solid, firm, gelatinous cut surface. Neoplasm is predominantly comprised of enlarged, extracellular accumulates of stromal mucin with minimal carcinoma cells suspended within extra-cellular mucin pools. Cuboidal or columnar epithelial cells configure cribriform or stellate cellular clusters or miniature tubules and strips of columnar cells along with signet ring cells. Colloid carcinoma pancreas is intensely immune reactive to CDX2, MUC2 and CEA. Neoplasm requires segregation from tumours as extravasation of benign stromal mucin, intra-ductal papillary mucinous neoplasm, mucinous cystic neoplasm or conventional pancreatic ductal adenocarcinoma. Colloid carcinoma pancreas is devoid of specific therapeutic guidelines or recommended treatment.
{"title":"Gum, Sap and Canker-Colloid Carcinoma-Pancreas","authors":"Anu Bajaj","doi":"10.56397/crms.2023.03.11","DOIUrl":"https://doi.org/10.56397/crms.2023.03.11","url":null,"abstract":"Colloid carcinoma pancreas is an infiltrative ductal epithelial neoplasm of pancreas characteristically denominating a preponderant (>80%) component of enlarged pools of extracellular stromal mucin pervaded with suspended neoplastic cells. Colloid carcinoma pancreas is a microsatellite stable tumefaction and exhibits KRAS genetic mutation confined to codon 12. Tumefaction is posited to arise from inverse polarization of cells with stromal mucin glycoproteins facing intrinsic cellular surface. Cogent clinical symptoms as abdominal or epigastric pain, pancreatitis, diarrhoea, hyperbilirubinemia or loss of weight are discerned. Tumefaction emerges as an enlarged, well demarcated lesion with a mean diameter of 5 centimetres and a solid, firm, gelatinous cut surface. Neoplasm is predominantly comprised of enlarged, extracellular accumulates of stromal mucin with minimal carcinoma cells suspended within extra-cellular mucin pools. Cuboidal or columnar epithelial cells configure cribriform or stellate cellular clusters or miniature tubules and strips of columnar cells along with signet ring cells. Colloid carcinoma pancreas is intensely immune reactive to CDX2, MUC2 and CEA. Neoplasm requires segregation from tumours as extravasation of benign stromal mucin, intra-ductal papillary mucinous neoplasm, mucinous cystic neoplasm or conventional pancreatic ductal adenocarcinoma. Colloid carcinoma pancreas is devoid of specific therapeutic guidelines or recommended treatment.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75304390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.56397/crms.2023.03.07
Nan-nan Zheng, Zhibin Li
A 51-year-old male patient was admitted to hospital with “1 week of restricted movement in left hip pain.” The patient denied trauma and had no other specific discomfort. Slightly reduced weight and physical strength, normal diet. No previous history of tuberculosis or exposure. Admission examination: no obvious abnormalities in the appearance of the spine, no tenderness and percussion pain. Left groin tenderness (+), left hip and buttock percussion pain (+), left 4-word experiment (+). Admission to complete relevant investigations: consider infectious lesions of the left pubic bone. After admission to the hospital and standardized treatment of tuberculosis, the patient's left pubic pain was significantly improved.
{"title":"Left Pubic Tuberculosis Was Misdiagnosed as Synovitis of the Left Hip","authors":"Nan-nan Zheng, Zhibin Li","doi":"10.56397/crms.2023.03.07","DOIUrl":"https://doi.org/10.56397/crms.2023.03.07","url":null,"abstract":"A 51-year-old male patient was admitted to hospital with “1 week of restricted movement in left hip pain.” The patient denied trauma and had no other specific discomfort. Slightly reduced weight and physical strength, normal diet. No previous history of tuberculosis or exposure. Admission examination: no obvious abnormalities in the appearance of the spine, no tenderness and percussion pain. Left groin tenderness (+), left hip and buttock percussion pain (+), left 4-word experiment (+). Admission to complete relevant investigations: consider infectious lesions of the left pubic bone. After admission to the hospital and standardized treatment of tuberculosis, the patient's left pubic pain was significantly improved.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75720940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.56397/crms.2023.03.13
Zhonghui Huang, Kui Liao
Nasopharyngeal carcinoma (NPC) is a malignant tumor that occurs in the nasopharynx. Its high incidence rate in certain regions of the world poses a significant challenge for healthcare providers. Imaging plays a crucial role in the diagnosis, treatment, and prognosis of NPC. Among various imaging modalities, diffusion-weighted imaging (DWI) has emerged as a promising technique due to its ability to provide functional information on tissue activity. This paper reviews the principles of DWI, its role in the diagnosis, treatment, and prognosis of NPC, and its potential applications in radiation therapy planning and treatment monitoring. DWI has been shown to have higher sensitivity and specificity for the detection of NPC compared to other imaging modalities. It can aid in the selection of radiation dose and target volumes, and monitor the timing and extent of treatment response. Further research is needed to explore the full potential of DWI in the management of NPC.
{"title":"A Review of the Role of DWI in Radiation Therapy Planning and Treatment Response Assessment for NPC Management","authors":"Zhonghui Huang, Kui Liao","doi":"10.56397/crms.2023.03.13","DOIUrl":"https://doi.org/10.56397/crms.2023.03.13","url":null,"abstract":"Nasopharyngeal carcinoma (NPC) is a malignant tumor that occurs in the nasopharynx. Its high incidence rate in certain regions of the world poses a significant challenge for healthcare providers. Imaging plays a crucial role in the diagnosis, treatment, and prognosis of NPC. Among various imaging modalities, diffusion-weighted imaging (DWI) has emerged as a promising technique due to its ability to provide functional information on tissue activity. This paper reviews the principles of DWI, its role in the diagnosis, treatment, and prognosis of NPC, and its potential applications in radiation therapy planning and treatment monitoring. DWI has been shown to have higher sensitivity and specificity for the detection of NPC compared to other imaging modalities. It can aid in the selection of radiation dose and target volumes, and monitor the timing and extent of treatment response. Further research is needed to explore the full potential of DWI in the management of NPC.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82184606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：