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Effect of the Combination of Native Herb with Motherwort on Anti-Inflammatory, Anti-Fatigue, and Hypertensive Hypoxia Tolerance 乡土植物与益母草联合抗炎、抗疲劳及高血压缺氧耐受性的影响
Pub Date : 2023-06-01 DOI: 10.56397/crms.2023.06.04
Han‐jun Ma, Shibo Zhao, Yuxin Wei, Zong-Qing He, Q. Wei, Xue‐Yi Huang, Qi Wei, Liyu Su, Suoyi Huang
Objective: To investigate the in vivo anti-inflammatory, anti-fatigue, and hypertensive hypoxia tolerance effects of earth ginseng with motherwort and its combination on mice. Methods: Male mice were divided into 6 groups according to their body weight: blank control group, native ginseng group, motherwort group, and three experimental groups with a 1:1 ratio of native ginseng and motherwort. 1.5, 4.5, and 7.5 g-kg-1 -d-1 were given to the three experimental groups. The blank control group was instilled with saline, and the earth ginseng group and motherwort group were given 1.5 g-kg -d-1-1 of the corresponding extracts. After 21 d of continuous gavage, the ear swelling test by xylene, the weight swimming test, and the high-pressure hypoxia tolerance test were performed. Also, the experimental indexes were measured, the liver weight was weighed, and the liver weight coefficient was calculated. Results: In the anti-inflammatory experiment, there was a significant difference in the swelling inhibition effect between the two single-flavored groups compared with the control group, the low-dose group compared with the two single-flavored groups, and the medium- and high-dose groups compared with the low-dose group (P < 0.05). In the weight swimming experiment and high-pressure hypoxia tolerance experiment, compared with the control group, the mice in the earth ginseng group and the motherwort group showed a significant improvement in weight swimming time and high-pressure hypoxia tolerance time (P<0.05); compared with the two single herb groups, the mice in the low dose group showed a statistically significant improvement in weight swimming time and high-pressure hypoxia tolerance time (P<0.05); compared with the low dose group, the mice in the high dose group showed a statistically significant improvement in weight swimming time and high-pressure hypoxia tolerance time (P<0.05). Compared with the low-dose group, the high-dose group had a statistically significant (P < 0.05) improvement in weight-bearing swimming time and hyperbaric hypoxia tolerance time. Compared with the control group, the liver weight coefficient of the earth ginseng group was statistically significant (P<0.05); compared with the two single herb groups, the liver weight coefficient of the low-dose group was statistically significant (P<0.05); compared with the low-dose group, the liver weight coefficient of the middle and high-dose groups were statistically significant (P<0.05). Conclusion: Native herbal medicine and its combination have significant anti-inflammatory, anti-fatigue, and high-pressure hypoxia tolerance effects, and the anti-inflammatory effect was positively correlated with the increase of the extract concentration; the anti-fatigue and high-pressure hypoxia tolerance effects were the best in the high-dose group.
目的:探讨土参与益母草及其联合用药对小鼠体内抗炎、抗疲劳、抗高血压缺氧的作用。方法:将雄性小鼠按体重分为空白对照组、土参组、益母草组和土参与益母草比例为1:1的3个实验组。3个实验组分别给予1.5、4.5、7.5 g-kg-1 -d-1。空白对照组灌胃生理盐水,土参组和益母草组灌胃相应提取物1.5 g-kg -d-1-1。连续灌胃21 d后,进行二甲苯耳肿胀试验、体重游泳试验和高压缺氧耐受性试验。测定试验指标,称量肝脏重量,计算肝脏重量系数。结果:在抗炎实验中,两种单一香料组与对照组相比,低剂量组与两种单一香料组相比,中、高剂量组与低剂量组相比,消肿效果有显著差异(P < 0.05)。在体重游泳实验和高压缺氧耐受实验中,与对照组相比,地参组和益母草组小鼠的体重游泳时间和高压缺氧耐受时间均有显著提高(P<0.05);与两单药组比较,低剂量组小鼠体重、游泳时间、高压缺氧耐受时间均有统计学意义(P<0.05);与低剂量组比较,高剂量组小鼠的体重、游泳时间和高压缺氧耐受时间均有统计学意义(P<0.05)。与低剂量组比较,高剂量组负重游泳时间、高压氧耐受时间均有统计学意义(P < 0.05)的改善。与对照组相比,土参组肝脏重量系数有统计学意义(P<0.05);与两单药组比较,低剂量组肝脏重量系数差异有统计学意义(P<0.05);与低剂量组比较,中、高剂量组肝脏重量系数均有统计学意义(P<0.05)。结论:中药及其复方具有显著的抗炎、抗疲劳、耐高压缺氧作用,且抗炎作用与提取物浓度的增加呈正相关;高剂量组抗疲劳和耐高压缺氧效果最好。
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引用次数: 0
Research Progress Based on Serious Complication of Stroke in Patients with Chronic Kidney Disease 慢性肾脏疾病患者卒中严重并发症的研究进展
Pub Date : 2023-06-01 DOI: 10.56397/crms.2023.06.07
Yunchuan Tian, Qingyang Zhu, Yonglian Tang, Rongkun Li, Jiang Xiao
Patients with chronic renal insufficiency (CKD) in the uremic stage can suffer various degrees of damage to various organ systems throughout the body, with the nervous system being common and severe. Chronic kidney disease (CKD) complicated with stroke has a high incidence and poor prognosis, which brings a heavy burden to patients and society. Understanding the risk factors of uremic patients complicated with stroke and taking preventive measures as soon as possible is of great significance for controlling the progress of the disease. The risk factors of uremic patients complicated with stroke are complex and diverse. Traditional risk factors include hypertension, diabetes, atrial fibrillation, dyslipidemia, etc. Non traditional risk factors such as genetic susceptibility, uremia, anemia, mineral and bone abnormalities can also promote the occurrence of stroke. In addition, dialysis related risk factors such as insufficient cerebral perfusion, increased arterial stiffness, and increased blood pressure variability can also cause stroke. Therefore, it is important to identify the risk factors of stroke in uremic patients as early as possible and take targeted preventive measures.
慢性肾功能不全(CKD)患者在尿毒症期可对全身各器官系统造成不同程度的损害,以神经系统为常见且严重。慢性肾脏疾病(CKD)合并脑卒中发病率高,预后差,给患者和社会带来了沉重的负担。了解尿毒症患者并发脑卒中的危险因素,尽早采取预防措施,对控制病情发展具有重要意义。尿毒症患者并发脑卒中的危险因素复杂多样。传统的危险因素包括高血压、糖尿病、心房颤动、血脂异常等。遗传易感性、尿毒症、贫血、矿物质和骨骼异常等非传统危险因素也可促进中风的发生。此外,与透析相关的危险因素,如脑灌注不足、动脉硬化增加和血压变异性增加也可引起中风。因此,尽早识别尿毒症患者发生脑卒中的危险因素,采取有针对性的预防措施十分重要。
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引用次数: 0
Description and Treatment Progress of Postpartum Body Pain in Chinese Medicine 产后躯体疼痛的中医描述及治疗进展
Pub Date : 2023-06-01 DOI: 10.56397/crms.2023.06.06
Yinhang Fu, Yingchun Tai, Yiyao Yang
Postpartum body pain is one of the common postpartum diseases, the damage to the patient’s physical and mental health can not be ignored. The recognition and treatment of postpartum body pain in traditional Chinese medicine mainly take qi and blood, Zang-fu organs and ying wei as the main points of syndrome differentiation. Its main etiology and pathogenesis are postpartum deficiency of qi and blood, wind-cold and dampness evil invading human body, the dysfunction of each viscera and the disharmony of camp and health. According to the cause, the treatment can be summarized as supplementing qi and blood, harmonizing Yingwei, dispelling wind and dispersing cold, activating collages and relieving pain, regulating zang fu organs and so on. TCM treatment focuses on the holistic view, and its systematic treatment through early intervention, multiple means and multiple approaches has the advantages of high safety, significant efficacy and low recurrence rate. Clinical syndrome differentiation is not limited to one of the above types, but this article can provide treatment ideas for this disease.
产后身体疼痛是常见的产后疾病之一,对患者身心健康的损害不容忽视。中医对产后体痛的认识和治疗主要以气血、脏腑、应纬为辨证要点。其主要病因病机是产后气血虚虚,风寒湿邪侵入人体,各脏腑功能失调,营与康不协调。根据病因,治疗可归纳为补气血、调和营卫、祛风散寒、活络止痛、调节脏腑等。中医治疗注重整体观,通过早期干预、多手段、多途径的系统治疗,具有安全性高、疗效显著、复发率低的优点。临床辨证并不局限于上述某一种类型,但本文可以为本病提供治疗思路。
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引用次数: 1
Knowledge, Perception and Feasibility of Community Health Influencers, Promoters and Service (CHIPS) Program Among Community Health Workers in Nkanu West and Awgu Local Government Areas, Enugu State, Nigeria 尼日利亚埃努古州西恩卡努和奥古地方政府地区社区卫生工作者对社区卫生影响者、推动者和服务(CHIPS)项目的认识、认知和可行性
Pub Date : 2023-06-01 DOI: 10.56397/crms.2023.06.11
N. Ugwunna, K. Enwonwu, C. Ani, B. Anozie, O. Arising, V. Aroh
Background: Primary health care (PHC) is the bedrock of our National Health Policy. PHC has two components: Community level and Primary health care facility level. Universal Health Cover cannot be achieved without significant investment in the community level component. Hitherto, the community component of PHC remains a neglected area of PHC program. CHIPS, a community-based programme was designed to allow traditional institution to select individuals who will administer basic medical needs and referring people in their communities to designated medical facilities when necessary. Method: This is a cross-sectional descriptive community-based study that was conducted among community health workers in Nkanu West and Awgu Local Government Areas of Enugu State Nigeria using self-administered questionnaire. Convenience sampling technique was used to select community health workers in the two local government areas. Results: 77.4% of the study population were not aware of the program. 26.9% are of the opinion that the families in the communities will welcome the idea of home visits. 23.3% perceived the implementation process to be slow, there was poor community awareness (22.0%), poor community participation (19.3%) and no community mobilization (19.3%) yet. Conclusion: From our study, the response rate on how best to organize CHIPS and the challenges it may face, is low. The striking thing is that the challenges of the past community health workers are still that of the present. So it is of utmost importance to constructively look at the content of the planning, implementation and its evaluation, and then draw strength from the weaknesses of the already existing community health programs.
背景:初级卫生保健(PHC)是我国国家卫生政策的基石。初级保健有两个组成部分:社区一级和初级保健设施一级。如果不对社区层面的组成部分进行大量投资,就无法实现全民健康覆盖。迄今为止,初级保健的社区组成部分仍然是初级保健计划中被忽视的领域。CHIPS是一项以社区为基础的方案,其目的是让传统机构选择个人来管理基本医疗需求,并在必要时将其社区中的人转介到指定的医疗设施。方法:这是一项基于社区的横断面描述性研究,在尼日利亚埃努古州西恩卡努和奥古地方政府地区的社区卫生工作者中使用自我管理问卷进行。采用便利抽样方法,选取两个地方政府辖区的社区卫生工作者。结果:77.4%的研究人群不知道该计划。26.9%的人认为社区的家庭会欢迎家访的想法。23.3%的人认为实施过程缓慢,社区意识差(22.0%),社区参与差(19.3%),尚未有社区动员(19.3%)。结论:从我们的研究来看,对如何更好地组织芯片及其可能面临的挑战的回复率较低。令人吃惊的是,过去社区卫生工作者面临的挑战仍然是现在面临的挑战。因此,最重要的是建设性地审视规划、实施和评估的内容,然后从现有社区卫生项目的弱点中汲取力量。
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引用次数: 0
Postpartum Hypogalactia Modern Treatment of Traditional Chinese Medicine 产后低乳症的现代中医治疗
Pub Date : 2023-06-01 DOI: 10.56397/crms.2023.06.13
Yiyao Yang, Yingchun Tai, Yinhang Fu
Postpartum hypogalactia was postpartum clinical common disease, mainly in breastfeeding, maternal milk little, or no milk, enough to feed the baby. Modern medicine thinks, milk secreted by the body’s neural and humoral regulation, hypothalamus and pituitary gland secretion of various hormones. Sucking and emptying of the breast is vital to maintain breast lactation. According to Chinese medicine, breast milk is produced by the body's qi, blood and fluids and depends on the flow of qi, which is the only way to produce enough milk to feed the baby. Maternal nutrition, sleep, mood can affect the normal secretion of milk juice. Breastfeeding is good for maternal and child are, in recent years, more and more get advocate and support. Hypogalactia of modern treatment has added new means and methods, including breast massage, “Three principles”, that is, the earlier they touch, early sucking, opened early milk; Acupuncture and cupping therapy; Psychological nursing intervention; Low frequency pulse for instrument and other advanced equipment. This paper mainly on postpartum hypogalactia heal 1 healing progress were reviewed, in order to provide reference for clinical treatment, better exert advantages of modern treatment of traditional Chinese medicine.
产后低乳症是产后临床常见病,主要表现在母乳喂养时,产妇乳汁少,或没有乳汁,不足以喂养婴儿。现代医学认为,乳汁是由人体的神经和体液调节分泌的,下丘脑和脑垂体分泌各种激素。吸吮和排空乳房对维持母乳喂养至关重要。根据中医的说法,母乳是由身体的气、血、液产生的,取决于气的流动,只有这样才能产生足够的奶来喂养婴儿。产妇的营养、睡眠、情绪都会影响乳汁的正常分泌。母乳喂养对母婴都有好处,近年来越来越得到倡导和支持。现代治疗低乳症又增加了新的手段和方法,包括乳房按摩“三原则”,即越早抚摸,越早吸吮,越早开奶;针灸拔罐疗法;心理护理干预;用于低频脉冲仪等先进设备。本文主要对产后低乳症的愈合进展进行综述,以期为临床治疗提供参考,更好地发挥现代中医治疗的优势。
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引用次数: 0
Progress in the Research of Reflux Nephropathy 反流性肾病的研究进展
Pub Date : 2023-06-01 DOI: 10.56397/crms.2023.06.01
Yunchuan Tian, Jiang Xiao, Yonglian Tang, Rongkun Li, Qingyang Zhu
Reflux nephropathy (RN) is a renal disease caused by Vesicoureteral Reflux (VUR) and Intrarenal Reflux (IRR), resulting in renal cortical scar (localized atrophy) and focal glomerulosclerosis. RN is one of the important causes of end-stage renal diseases (ESRD). The most basic pathological feature of RN is kidney scarring. Common clinical manifestations are persistent or recurrent urinary tract infection, albuminuria, hypertension, nocturia, polyuria, lumbago, urinary calculi, etc. Due to the hidden condition of RN, doctors in various departments, especially in pediatrics, nephrology and urology, must strengthen their understanding and understanding of this disease, so as to facilitate the early detection and diagnosis of this disease. Correct conservative treatment of Western medicine, surgical treatment when necessary, and reasonable integrated treatment of Chinese and Western medicine are of great significance for the prevention and treatment of the progression from RN to ESRD.
反流性肾病(RN)是一种由膀胱输尿管反流(VUR)和肾内反流(IRR)引起的肾脏疾病,导致肾皮质瘢痕(局部萎缩)和局灶性肾小球硬化。RN是终末期肾脏疾病(ESRD)的重要病因之一。肾脏瘢痕形成是肾炎最基本的病理特征。常见临床表现为持续性或反复性尿路感染、蛋白尿、高血压、夜尿、多尿、腰痛、尿路结石等。由于RN的隐蔽性,各科室尤其是儿科、肾病科、泌尿科的医生必须加强对本病的认识和认识,便于本病的早期发现和诊断。正确的西医保守治疗,必要时进行手术治疗,合理的中西医结合治疗,对预防和治疗RN向ESRD进展具有重要意义。
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引用次数: 0
Natural Processes and Hygiene to Protect Against Spread and Mutations of COVID-19 预防COVID-19传播和突变的自然过程和卫生
Pub Date : 2023-06-01 DOI: 10.56397/crms.2023.06.02
E. Bryndin, I. Bryndina
Our planet is a living being that has its own protective viral mechanism. Viruses are activated when people intervene too zealously in the natural processes on the planet and worsen the environment. With a decrease in the spiritual level of society, deterioration of the environment, climate change, pollution of water and soil and other catastrophic violations of natural processes on the planet, an epidemic and the process of mutation of viruses begins, as a result of which more and more of their species and strains appear. The coronavirus is becoming more and more infectious, more and more often affects the young and, according to some reports, aggravates the course of the disease. COVID-19 acquires variability and increases infectiousness in people with weak immunity. Mutations of COVID-19 and infection will stop if the path of transmission of coronavirus from person to person is interrupted. To do this, you need to observe natural and medical protective measures, acquire appropriate knowledge and skills and have protective equipment available.
我们的星球是一个有生命的存在,它有自己的病毒保护机制。当人们过分热心地干预地球上的自然过程并使环境恶化时,病毒就会被激活。随着社会精神水平的下降、环境的恶化、气候变化、水和土壤的污染以及对地球自然进程的其他灾难性破坏,流行病和病毒变异的过程开始了,结果出现了越来越多的病毒种类和毒株。这种冠状病毒的传染性越来越强,越来越多地影响年轻人,据一些报道,它还会加剧疾病的进程。COVID-19在免疫力较弱的人群中具有变异性并增加传染性。如果冠状病毒的人际传播途径被阻断,COVID-19的突变和感染就会停止。为此,您需要遵守自然防护措施和医疗防护措施,掌握适当的知识和技能,并配备防护设备。
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引用次数: 0
Advances in the Diagnosis and Treatment of Cardiogenic Shock in Chinese Medicine and Research 心源性休克的中医诊治与研究进展
Pub Date : 2023-06-01 DOI: 10.56397/crms.2023.06.05
Ming-Hao Sun, Yuewei Li, Shibo Zhao, Zhonggang Wu, Xiuling Wei
Cardiogenic shock belongs to a group of acute and critical illnesses in cardiovascular medicine with a high mortality rate and poor prognosis. Traditional Chinese medicine, as the crystallization of traditional wisdom of Chinese medicine, has made certain progress in the treatment of cardiogenic shock and in improving the prognosis of such patients. This article reviews the latest research results and related reports on the treatment of cardiogenic shock in Chinese medicine, intending to provide front-line clinical workers with treatment ideas and references.
心源性休克是心血管医学中一组病死率高、预后差的急危性疾病。中医作为中医传统智慧的结晶,在治疗心源性休克和改善心源性休克患者预后方面取得了一定的进展。本文对心源性休克中医治疗的最新研究成果及相关报道进行综述,旨在为一线临床工作者提供治疗思路和参考。
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引用次数: 0
Low Health Literacy (LHL) Facts 低健康素养(LHL)事实
Pub Date : 2023-06-01 DOI: 10.56397/crms.2023.06.03
Abdul Kader Mohiuddin
In order to access, comprehend, and use information to make decisions about their health, people must possess certain personal traits and social resources, which are referred to as health literacy. It can assist us in maintaining good health, preventing illness, and effectively managing existing illnesses. The degree to which a person can locate, comprehend, and make use of information and services to support health-related decisions and actions for themselves and others is known as personal health literacy. Low health literacy is linked to more hospitalizations, more use of emergency care, less use of preventative services, and a worsened ability to understand labels and health messages, a worsened state of health, higher mortality, and more expensive medical care.
为了获取、理解和使用信息来作出有关其健康的决定,人们必须具备某些个人特征和社会资源,这些特征和资源被称为健康素养。它可以帮助我们保持健康,预防疾病,并有效地管理现有的疾病。一个人能够找到、理解和利用信息和服务来支持自己和他人作出与健康有关的决定和行动的程度被称为个人健康素养。低卫生素养与更多的住院、更多的使用紧急护理、更少的使用预防性服务、更差的理解标签和健康信息的能力、更差的健康状况、更高的死亡率和更昂贵的医疗保健有关。
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引用次数: 0
A Bibliometric Analysis of Tea and Bone from 1989 to 2023 1989 - 2023年《茶与骨》文献计量学分析
Pub Date : 2023-06-01 DOI: 10.56397/crms.2023.06.14
Dongping Wan, Rui Tang, Shihang Cao, Qiang Zan
Background: An increasing body of research has demonstrated a close association between the timing, type, and quantity of tea consumption and bone metabolism and skeletal health. However, to date, there has been a scarcity of systematic literature reviews and quantitative analyses in this field. This project aims to employ a bibliometric approach to systematically analyze and summarize the research on tea and bone health from 1989 to 2023. By visualizing the research hotspots and trends, we seek to gain a comprehensive understanding of the current status of research in this area. Methods: Relevant research articles were retrieved from the Web of Science Core Collection (WoSCC). The collected articles were then subjected to statistical and visualization analyses using CiteSpace and VOSviewer. Key aspects analyzed included the annual publication output, active countries, prolific institutions, authors, core journals, references, and keywords. Results: In total, 932 articles were selected from the WOSCC database, showing an increasing trend in annual publication output. The highest number of publications originated from China (240 articles, accounting for 25.75%), followed by the USA (196 articles, accounting for 21.03%) and Japan (105 articles, accounting for 11.27%). Among institutions, Texas Tech University emerged as the most prolific in terms of productivity, while author Shen, Chwan-Li contributed the highest number of publications (27 articles). The research hotspots in the field of tea and bone studies were identified as osteogenic differentiation, inflammation, and mesenchymal stem cells. Conclusions: The field of tea and bone research is experiencing a vibrant expansion, with ongoing investigations focusing on the intricate connections between tea and inflammation, as well as the mechanisms underlying tea’s impact on bone cell differentiation. However, further exploration is warranted to elucidate and delve deeper into these mechanisms in order to enhance our comprehension in this area.
背景:越来越多的研究表明,喝茶的时间、类型和数量与骨骼代谢和骨骼健康密切相关。然而,迄今为止,在这一领域还缺乏系统的文献综述和定量分析。本项目旨在采用文献计量学的方法,对1989年至2023年茶与骨骼健康的研究进行系统的分析和总结。通过可视化研究热点和趋势,我们寻求对该领域的研究现状有一个全面的了解。方法:从Web of Science Core Collection (WoSCC)检索相关研究文章。然后使用CiteSpace和VOSviewer对收集到的文章进行统计和可视化分析。分析的主要方面包括年度出版产出、活跃国家、高产机构、作者、核心期刊、参考文献和关键词。结果:从WOSCC数据库中共筛选出932篇论文,年发表量呈上升趋势。发表最多的是中国(240篇,占25.75%),其次是美国(196篇,占21.03%)和日本(105篇,占11.27%)。在院校中,得克萨斯理工大学(Texas Tech University)的生产率最高,而作者沈川李(Shen, chwanli,音译)发表的论文最多(27篇)。目前茶与骨研究领域的研究热点是成骨分化、炎症和间充质干细胞。结论:茶和骨骼的研究领域正在蓬勃发展,正在进行的研究主要集中在茶和炎症之间的复杂联系,以及茶对骨细胞分化的影响机制。然而,为了提高我们对这一领域的理解,进一步的探索是必要的,以阐明和深入研究这些机制。
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引用次数: 0
期刊
Current research in medical sciences
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