Pub Date : 2024-01-24DOI: 10.31487/j.dobcr.2024.01.01
Kriti Agarwal, Krishna Sireesha Sundaragiri, Shikha Saxena, A. Bhargava, B. Sankhla, Jaswant Singh
Oral potentially malignant disorders encompass a spectrum of lesions that present an increased risk of progressing to oral cancer. Timely and accurate diagnosis, as well as effective risk prediction, are crucial for early intervention and improved patient outcomes. In recent years, the integration of artificial intelligence has emerged as a transformative approach in the realm of medical diagnostics, offering innovative tools to enhance the precision and efficiency of disease identification and risk assessment. Notably, artificial intelligence driven image analysis techniques have demonstrated remarkable potential in interpreting oral lesion images, aiding in the accurate identification of morphological characteristics associated with these oral lesions. This review explores the evolving role of AI in the clinical diagnosis and risk prediction of these disorders.
{"title":"Role Of Artificial Intelligence in Clinical Diagnosis of Oral Potentially Malignant Disorders: A Scoping Review","authors":"Kriti Agarwal, Krishna Sireesha Sundaragiri, Shikha Saxena, A. Bhargava, B. Sankhla, Jaswant Singh","doi":"10.31487/j.dobcr.2024.01.01","DOIUrl":"https://doi.org/10.31487/j.dobcr.2024.01.01","url":null,"abstract":"Oral potentially malignant disorders encompass a spectrum of lesions that present an increased risk of progressing to oral cancer. Timely and accurate diagnosis, as well as effective risk prediction, are crucial for early intervention and improved patient outcomes. In recent years, the integration of artificial intelligence has emerged as a transformative approach in the realm of medical diagnostics, offering innovative tools to enhance the precision and efficiency of disease identification and risk assessment. Notably, artificial intelligence driven image analysis techniques have demonstrated remarkable potential in interpreting oral lesion images, aiding in the accurate identification of morphological characteristics associated with these oral lesions. This review explores the evolving role of AI in the clinical diagnosis and risk prediction of these disorders.","PeriodicalId":72781,"journal":{"name":"Dental Oral Biology and Craniofacial Research","volume":"18 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139599919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-19DOI: 10.31487/j.dobcr.2023.02.01
Ganesh Sai Sandeep Kumar, Ganesh Sai Sandeep Kumar, L. Krishna Prasad, P. Srinivas Chakravarthi, P. Raja Satish, Anand Vijay S, Vidya Sagar B, K. S. Deekshith
Aim and Objectives: Evaluation of socket preservation using collagen plug and injectable platelet rich fibrin in extracted sockets of mandibular molars. To evaluate wound healing and bone density using collagen plug and I-PRF and to compare wound healing and bone density between collagen plug and I-PRF. Methodology: This experimental study involves 13 healthy patients at the Sibar Institute of Dental Sciences and Hospital in Guntur, Andhra Pradesh, India, who underwent mandibular molar extraction under local anesthesia. Patients underwent clinical and radio-graphic examinations and received periodontal treatment. The study involved extraction of right and left mandibular molar teeth, AbGel placement, collagen plug placement, and sockets secured with sutures and pressure packs. Postoperative pain, swelling, and wound healing were assessed using Wong-Baker faces pain rating scale, VAS scale, and LANDRY healing index. CBCT was obtained after 1 month and 3 months after extraction for bone quality assessment. Results: In the study, there were 69.2% men and 30.8% women. According to the study, 14.3% of individuals in the collagen plug group and 85.7% of those who received injectable platelet-rich fibrin experienced very good wound healing. On the first and seventh days, the mean pain intensity was lower in the injectable group, but there was not a noticeable distinction between the groups. The injectable group had the lowest swelling score, but by day seven, it had dramatically decreased. At the third month, the collagen plug group had the highest bone density readings, with no discernible difference between the groups. Conclusion: It can be concluded that I-PRF can be utilized as an alternative to collagen plug.
{"title":"Evaluation of Socket Preservation Using Collagen Plug and Injectable Platelet Rich Fibrin in Extracted Sockets of Mandibular Molars: A Split Mouth Study","authors":"Ganesh Sai Sandeep Kumar, Ganesh Sai Sandeep Kumar, L. Krishna Prasad, P. Srinivas Chakravarthi, P. Raja Satish, Anand Vijay S, Vidya Sagar B, K. S. Deekshith","doi":"10.31487/j.dobcr.2023.02.01","DOIUrl":"https://doi.org/10.31487/j.dobcr.2023.02.01","url":null,"abstract":"Aim and Objectives: Evaluation of socket preservation using collagen plug and injectable platelet rich fibrin in extracted sockets of mandibular molars. To evaluate wound healing and bone density using collagen plug and I-PRF and to compare wound healing and bone density between collagen plug and I-PRF. Methodology: This experimental study involves 13 healthy patients at the Sibar Institute of Dental Sciences and Hospital in Guntur, Andhra Pradesh, India, who underwent mandibular molar extraction under local anesthesia. Patients underwent clinical and radio-graphic examinations and received periodontal treatment. The study involved extraction of right and left mandibular molar teeth, AbGel placement, collagen plug placement, and sockets secured with sutures and pressure packs. Postoperative pain, swelling, and wound healing were assessed using Wong-Baker faces pain rating scale, VAS scale, and LANDRY healing index. CBCT was obtained after 1 month and 3 months after extraction for bone quality assessment. Results: In the study, there were 69.2% men and 30.8% women. According to the study, 14.3% of individuals in the collagen plug group and 85.7% of those who received injectable platelet-rich fibrin experienced very good wound healing. On the first and seventh days, the mean pain intensity was lower in the injectable group, but there was not a noticeable distinction between the groups. The injectable group had the lowest swelling score, but by day seven, it had dramatically decreased. At the third month, the collagen plug group had the highest bone density readings, with no discernible difference between the groups. Conclusion: It can be concluded that I-PRF can be utilized as an alternative to collagen plug.","PeriodicalId":72781,"journal":{"name":"Dental Oral Biology and Craniofacial Research","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135730688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-08DOI: 10.31487/j.dobcr.2023.01.03
Ridhi Bhola, A. Narwal, M. Kamboj, A. Devi, Virendra Singh
Epidermoid cyst in the floor of mouth is a very rare non-neoplastic cyst lined by squamous epithelium. Here is a case report of a 17-year-old female who presented with a slow growing swelling in the floor of mouth with difficulty in breathing and swallowing from past 4 months. A clinical diagnosis of ranula was made. Biopsy and subsequent histopathological evaluation revealed it as epidermoid cyst. Thus, epidermoid cyst of the floor of mouth can mimic ranula in its clinical presentation. Therefore, histopathologic evaluation is critical in making definitive diagnosis in such scenarios. A detailed account of clinical, radiological and histopathological evaluation has been presented.
{"title":"Sublingual Swelling Masquerades a Ranula: A Case Report and Review of the Literature","authors":"Ridhi Bhola, A. Narwal, M. Kamboj, A. Devi, Virendra Singh","doi":"10.31487/j.dobcr.2023.01.03","DOIUrl":"https://doi.org/10.31487/j.dobcr.2023.01.03","url":null,"abstract":"Epidermoid cyst in the floor of mouth is a very rare non-neoplastic cyst lined by squamous epithelium. Here is a case report of a 17-year-old female who presented with a slow growing swelling in the floor of mouth with difficulty in breathing and swallowing from past 4 months. A clinical diagnosis of ranula was made. Biopsy and subsequent histopathological evaluation revealed it as epidermoid cyst. Thus, epidermoid cyst of the floor of mouth can mimic ranula in its clinical presentation. Therefore, histopathologic evaluation is critical in making definitive diagnosis in such scenarios. A detailed account of clinical, radiological and histopathological evaluation has been presented.","PeriodicalId":72781,"journal":{"name":"Dental Oral Biology and Craniofacial Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44200200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: This study focused to evaluate the potency of injection Placentrex® by assessing the rate of soft tissue healing with bilateral symmetrical third molar impaction by using early wound healing score. Materials and Methods: The split mouth study included 23 patients with bilaterally symmetrical third molar impaction. Randomly one side was selected as study group and other side as control group. 2 ml of Placentrex® injection was administered submucosally before surgical removal on the buccal and retromolar region in study group while control group was allowed to heal naturally. Parameters like soft tissue healing, pain, trismus and swelling were assessed on 1st,3rd and 7th post operative days. Early healing score was used to assess the soft tissue healing after surgical removal. Results: The mean re-epithelialization based on CSR on 3rd post operative day showed characteristic significance with mean score of 4.56 (p<0.05) when compared to the control group which showed a mean score of 2.73. The inflammation based on CSI on 3rd postoperative day for the study group revealed a mean value of 1.73 (p<0.05) whereas for the control group a mean of 1.04 was recorded proving significance. It was found that there was no significant statistical difference in the case and control group in relevance to post operative pain, swelling and mouth opening. Conclusion: Placentrex® exhibited characteristic significance in early soft tissue healing with signs of less inflammation and early reepithelialisation.
背景：本研究的重点是通过使用早期伤口愈合评分评估双侧对称性第三磨牙嵌塞的软组织愈合率来评估注射Placentrex®的效力。材料和方法：对23例双侧对称性第三磨牙嵌塞患者进行了分口研究。随机选择一侧作为研究组，另一侧作为对照组。研究组在口腔和磨牙后区域手术切除前，在粘膜下注射2 ml Placentrex®注射液，而对照组则允许其自然愈合。术后第1、3和7天评估软组织愈合、疼痛、三体和肿胀等参数。早期愈合评分用于评估手术切除后软组织的愈合情况。结果：术后第3天基于CSR的平均再上皮化显示出特征性意义，平均得分为4.56（p<0.05），而对照组的平均得分为2.73。研究组术后第3天基于CSI的炎症显示平均值为1.73（p<0.05），而对照组的平均值为1.04，证明了这一点。研究发现，病例组和对照组在术后疼痛、肿胀和开口方面没有显著的统计学差异。结论：Placentrex®在早期软组织愈合中表现出显著的特征性意义，有炎症减少和早期再上皮化的迹象。
{"title":"Does Submucosal Placentrex® Injection Hasten the Soft Tissue Healing in Mandibular Third Molar Impaction Surgery? A Prospective Randomized Split-Mouth Study","authors":"Nakkeeran Komagan Prabhu, Ajinkya Naik, Selvakumar Thulasiraman, Velavan Krishnan, Krishna Kumar Raja V.B","doi":"10.31487/j.dobcr.2023.01.02","DOIUrl":"https://doi.org/10.31487/j.dobcr.2023.01.02","url":null,"abstract":"Background: This study focused to evaluate the potency of injection Placentrex® by assessing the rate of soft tissue healing with bilateral symmetrical third molar impaction by using early wound healing score.\u0000Materials and Methods: The split mouth study included 23 patients with bilaterally symmetrical third molar impaction. Randomly one side was selected as study group and other side as control group. 2 ml of Placentrex® injection was administered submucosally before surgical removal on the buccal and retromolar region in study group while control group was allowed to heal naturally. Parameters like soft tissue healing, pain, trismus and swelling were assessed on 1st,3rd and 7th post operative days. Early healing score was used to assess the soft tissue healing after surgical removal. \u0000Results: The mean re-epithelialization based on CSR on 3rd post operative day showed characteristic significance with mean score of 4.56 (p<0.05) when compared to the control group which showed a mean score of 2.73. The inflammation based on CSI on 3rd postoperative day for the study group revealed a mean value of 1.73 (p<0.05) whereas for the control group a mean of 1.04 was recorded proving significance. It was found that there was no significant statistical difference in the case and control group in relevance to post operative pain, swelling and mouth opening. \u0000Conclusion: Placentrex® exhibited characteristic significance in early soft tissue healing with signs of less inflammation and early reepithelialisation.","PeriodicalId":72781,"journal":{"name":"Dental Oral Biology and Craniofacial Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48350293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-28DOI: 10.31487/j.dobcr.2023.01.01
Madhur Sharma, A. Narwal, A. Devi, M. Kamboj
Around 1-1.5 % of all malignant tumors in oral cavity are caused by metastatic dissemination to this region. Lung, kidney, breast, bone and colorectal regions are primary sites which act as source of metastases to oral cavity. Similarly, metastasis from primary oral malignancy to distant sites is not uncommon with metastasis mainly occurring to lung, followed by bone and liver. Here we report 2 cases showing different primary origins but presentation in oral cavity being the first symptom. One case is of an 82 year old male with a complaint of swelling in right mandible and a diagnosis of prostatic adenocarcinoma metastasizing to oral cavity was established. The other case presented here is of a 42 year old male with pain and swelling in right mandible. The diagnosis of adenoid cystic carcinoma was made and a full body scan helped in early identification of metastatic deposits in lung. Despite the infrequent occurrence of metastases in oral region, dental surgeon should be aware of the possibilities for correct diagnostic conduction and subsequently, the initiation of treatment in early stages of disease.
{"title":"Finding the Way Back Home: Report of 2 Cases of Oral Metastasis","authors":"Madhur Sharma, A. Narwal, A. Devi, M. Kamboj","doi":"10.31487/j.dobcr.2023.01.01","DOIUrl":"https://doi.org/10.31487/j.dobcr.2023.01.01","url":null,"abstract":"Around 1-1.5 % of all malignant tumors in oral cavity are caused by metastatic dissemination to this region. Lung, kidney, breast, bone and colorectal regions are primary sites which act as source of metastases to oral cavity. Similarly, metastasis from primary oral malignancy to distant sites is not uncommon with metastasis mainly occurring to lung, followed by bone and liver. Here we report 2 cases showing different primary origins but presentation in oral cavity being the first symptom. One case is of an 82 year old male with a complaint of swelling in right mandible and a diagnosis of prostatic adenocarcinoma metastasizing to oral cavity was established. The other case presented here is of a 42 year old male with pain and swelling in right mandible. The diagnosis of adenoid cystic carcinoma was made and a full body scan helped in early identification of metastatic deposits in lung. Despite the infrequent occurrence of metastases in oral region, dental surgeon should be aware of the possibilities for correct diagnostic conduction and subsequently, the initiation of treatment in early stages of disease.","PeriodicalId":72781,"journal":{"name":"Dental Oral Biology and Craniofacial Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45895744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-12DOI: 10.31487/j.dobcr.2022.04.02
Ibañez Juan Carlos, Loys Adrián Esteban, Maestri Juan, Ibanez Martin, Dalla Costa Lucas, Ibanez María Constanza
The present article describes the TSC Protocol (tubes, support, connectors) version 2.2 for construction of surgical guides for implant placement and the possibility of insertion of the implants also.
{"title":"Protocol T.A.C (T.S.C.) 2.2 for Making Surgical Guides — The Sliding-Tube Concept","authors":"Ibañez Juan Carlos, Loys Adrián Esteban, Maestri Juan, Ibanez Martin, Dalla Costa Lucas, Ibanez María Constanza","doi":"10.31487/j.dobcr.2022.04.02","DOIUrl":"https://doi.org/10.31487/j.dobcr.2022.04.02","url":null,"abstract":"The present article describes the TSC Protocol (tubes, support, connectors) version 2.2 for construction of surgical guides for implant placement and the possibility of insertion of the implants also.","PeriodicalId":72781,"journal":{"name":"Dental Oral Biology and Craniofacial Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49332820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-20DOI: 10.31487/j.dobcr.2022.03.02
G. Moncada, Daniel Cortes Sylvester, M. S. López, María Ines Navarrete, Camila Venegas, Greisy Yanira Zambrano, R. Millas
Objective: The aims of this study were to detect the fibrocartilage layer (FC) of the porcine mandible condyle in ex vivo preparations using 3D SPGR (Spoiled GRASS sequence) (T1 WATS) sequences, and, to compare 3D SPGR image results with those of conventional magnetic resonance imaging (MRI) sequences for detecting the fibrocartilage layers of the temporomandibular joint (TMJ) in patients with temporomandibular disorders (TMD). Methods: Four porcine TMJ with and without FC were radiographically and histologically assessed. Additionally, fifty-nine patients were studied using T1 WATS MRI and T2 TSE and PD TSE sequences. Four trained and calibrated observers assessed the MRI images. Results: In porcine, the T1 WATS sequence was able to detect the presence or absence of FC in the mandibular condyle, histologically confirmed. In humans, 98% of fibrocartilages were detected with T1 WATS sequence in temporal fossa, and 91% in mandible condyles. Significantly poorer detection with the T2 TSE and PD TSE sequences was observed. Mean fibrocartilage ROI signal intensity was 74.07 IU (±14.7), without statistical differences between fossa and condyle. Conclusion: T1 WATS is the most reliable and efficient sequence for detecting the TMJ fibrocartilage layer (p <0.05).
{"title":"Detection of the Temporomandibular Joint Fibrocartilage by Magnetic Resonance Imaging","authors":"G. Moncada, Daniel Cortes Sylvester, M. S. López, María Ines Navarrete, Camila Venegas, Greisy Yanira Zambrano, R. Millas","doi":"10.31487/j.dobcr.2022.03.02","DOIUrl":"https://doi.org/10.31487/j.dobcr.2022.03.02","url":null,"abstract":"Objective: The aims of this study were to detect the fibrocartilage layer (FC) of the porcine mandible condyle in ex vivo preparations using 3D SPGR (Spoiled GRASS sequence) (T1 WATS) sequences, and, to compare 3D SPGR image results with those of conventional magnetic resonance imaging (MRI) sequences for detecting the fibrocartilage layers of the temporomandibular joint (TMJ) in patients with temporomandibular disorders (TMD). \u0000Methods: Four porcine TMJ with and without FC were radiographically and histologically assessed. Additionally, fifty-nine patients were studied using T1 WATS MRI and T2 TSE and PD TSE sequences. Four trained and calibrated observers assessed the MRI images. \u0000Results: In porcine, the T1 WATS sequence was able to detect the presence or absence of FC in the mandibular condyle, histologically confirmed. In humans, 98% of fibrocartilages were detected with T1 WATS sequence in temporal fossa, and 91% in mandible condyles. Significantly poorer detection with the T2 TSE and PD TSE sequences was observed. Mean fibrocartilage ROI signal intensity was 74.07 IU (±14.7), without statistical differences between fossa and condyle. \u0000Conclusion: T1 WATS is the most reliable and efficient sequence for detecting the TMJ fibrocartilage layer (p <0.05).","PeriodicalId":72781,"journal":{"name":"Dental Oral Biology and Craniofacial Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41985250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-16DOI: 10.31487/j.dobcr.2022.03.01
G. Moncada, Gabriela Díaz Mujica, C. Valdés
Objective: Evaluate the evidence of the clinical correlation between vitamin D and symptomatic degenerative joint disease. Methods: A systematic search and meta-analysis was conducted of randomized controlled studies (RCTs) published in between January 1st, 2010, and March 30th, 2020 on five different databases. The study population consisted of adult patients with symptomatic knee osteoarthritis; the intervention was vitamin D; the comparison was placebo, and the outcomes included the Western Ontario and McMaster Universities Arthritis Index (WOMAC) (pain, function, stiffness), tibial cartilage volume, synovial tissue volume (STV), subchondral bone marrow lesion (BML) volume, effusion-synovitis, serum vitamin D3 levels, serological inflammatory and metabolic biomarkers levels and adverse events. Results: Nine RCTs involving 2,168 patients were included in this study. Pooled estimates suggested that vitamin D supplementation was associated with reduction in WOMAC pain (Std. Mean=1.08(0.90, 1.25); I2=99%; p=0.00001), function (Mean=1.1(0.92, 1.27); I2=99%; p=0.00001), stiffness (Std. mean= 0.72(0.54, 0.90); I2=98%; p=0.00001) and synovial effusion in the suprapatellar pouch numbers. There was no significant difference in tibial cartilage volume incidence (Std. Mean=0.26(0.44, 0.80); I2=99%; p=0.00001), STV, BML volume, inflammatory biomarkers and adverse events between the vitamin D and the placebo groups. Conclusion: Vitamin D supplementation was effective in improving WOMAC pain and function in patients with knee OA and also improved serological vitamin D levels. However, it had no beneficial effect on structural cartilage change or inflammatory biomarker reduction. Therefore, there is currently a lack of evidence on vitamin D regimen dosage and length to obtain benefits in preventing knee disease progression.
{"title":"Correlation Between Vitamin D and Degenerative Joint Disorders: Review and Meta-Analysis","authors":"G. Moncada, Gabriela Díaz Mujica, C. Valdés","doi":"10.31487/j.dobcr.2022.03.01","DOIUrl":"https://doi.org/10.31487/j.dobcr.2022.03.01","url":null,"abstract":"Objective: Evaluate the evidence of the clinical correlation between vitamin D and symptomatic degenerative joint disease. \u0000Methods: A systematic search and meta-analysis was conducted of randomized controlled studies (RCTs) published in between January 1st, 2010, and March 30th, 2020 on five different databases. The study population consisted of adult patients with symptomatic knee osteoarthritis; the intervention was vitamin D; the comparison was placebo, and the outcomes included the Western Ontario and McMaster Universities Arthritis Index (WOMAC) (pain, function, stiffness), tibial cartilage volume, synovial tissue volume (STV), subchondral bone marrow lesion (BML) volume, effusion-synovitis, serum vitamin D3 levels, serological inflammatory and metabolic biomarkers levels and adverse events.\u0000Results: Nine RCTs involving 2,168 patients were included in this study. Pooled estimates suggested that vitamin D supplementation was associated with reduction in WOMAC pain (Std. Mean=1.08(0.90, 1.25); I2=99%; p=0.00001), function (Mean=1.1(0.92, 1.27); I2=99%; p=0.00001), stiffness (Std. mean= 0.72(0.54, 0.90); I2=98%; p=0.00001) and synovial effusion in the suprapatellar pouch numbers. There was no significant difference in tibial cartilage volume incidence (Std. Mean=0.26(0.44, 0.80); I2=99%; p=0.00001), STV, BML volume, inflammatory biomarkers and adverse events between the vitamin D and the placebo groups. \u0000Conclusion: Vitamin D supplementation was effective in improving WOMAC pain and function in patients with knee OA and also improved serological vitamin D levels. However, it had no beneficial effect on structural cartilage change or inflammatory biomarker reduction. Therefore, there is currently a lack of evidence on vitamin D regimen dosage and length to obtain benefits in preventing knee disease progression.","PeriodicalId":72781,"journal":{"name":"Dental Oral Biology and Craniofacial Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45999159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-24DOI: 10.31487/j.dobcr.2022.02.01
Shrishtee Goyal, Narayan B. Kulakrni
Introduction: Introduction of digital technology in orthodontics has improved the overall experience for the patient as well as the clinician. This study aimed to assess knowledge, attitude and practice of digital orthodontics among orthodontists and orthodontic residents in Gujarat through a questionnaire. Materials and Methods: The questionnaire comprised of two parts, the first part which consisted of sociodemographic details (5 questions) and the second part consisted of questions to assess the knowledge (2 questions), attitude (9 questions) and practice (3 questions) of digital orthodontics. The final developed questionnaire after content validity was sent to Orthodontists and Orthodontic residents as Google Form link to Gujrat Orthodontic Study Group over WhatsApp and the received responses were recorded. Results: Kolmogorov- Smirnov test was employed to test the normality of data. Chi Square test was performed for the quantitative variables. Results showed that majority of the participants knew about availability of digital orthodontics. Revealed a positive incline in incorporating digital orthodontics in their routine practice. However, a lack was observed in practicing digital orthodontics among Orthodontists and Orthodontic Residents of Gujarat Statistically significant difference was present regarding the awareness about digital orthodontics between males and females (p value = 0.042). Conclusion: Orthodontists and orthodontic residents of Gujarat displayed adequate knowledge, positive attitude and lack of practice about digital orthodontics. Male population is more aware about digital technologies as compared to female population.
导读:数字技术在正畸治疗中的应用，提高了患者和临床医生的整体体验。本研究旨在通过问卷调查来评估古吉拉特邦正畸医师和正畸居民对数字正畸的知识、态度和实践情况。材料与方法:问卷分为两部分，第一部分为社会人口学资料(5题)，第二部分为数字正畸知识(2题)、态度(9题)和实践(3题)评估。内容效度后的最终问卷以谷歌形式通过WhatsApp链接到Gujrat Orthodontic Study Group，发送给正畸医师和正畸住院医师，并记录收到的回复。结果:采用Kolmogorov- Smirnov检验检验数据的正态性。对定量变量进行卡方检验。结果显示，大多数参与者知道数字正畸的可用性。显示在日常实践中纳入指指正畸的积极倾向。然而，古吉拉特邦的正畸医生和正畸居民对数字正畸的认知度缺乏，男女对数字正畸的认知度差异有统计学意义(p值= 0.042)。结论:古吉拉特邦正畸医师和正畸居民对数字正畸的认识、态度和实践不足。男性比女性更了解数字技术。
{"title":"Assessment of Knowledge, Attitude and Practice of Digital Orthodontics Among Orthodontists and Orthodontic Residents in Gujarat: A Questionnaire Study","authors":"Shrishtee Goyal, Narayan B. Kulakrni","doi":"10.31487/j.dobcr.2022.02.01","DOIUrl":"https://doi.org/10.31487/j.dobcr.2022.02.01","url":null,"abstract":"Introduction: Introduction of digital technology in orthodontics has improved the overall experience for the patient as well as the clinician. This study aimed to assess knowledge, attitude and practice of digital orthodontics among orthodontists and orthodontic residents in Gujarat through a questionnaire.\u0000Materials and Methods: The questionnaire comprised of two parts, the first part which consisted of sociodemographic details (5 questions) and the second part consisted of questions to assess the knowledge (2 questions), attitude (9 questions) and practice (3 questions) of digital orthodontics. The final developed questionnaire after content validity was sent to Orthodontists and Orthodontic residents as Google Form link to Gujrat Orthodontic Study Group over WhatsApp and the received responses were recorded.\u0000Results: Kolmogorov- Smirnov test was employed to test the normality of data. Chi Square test was performed for the quantitative variables. Results showed that majority of the participants knew about availability of digital orthodontics. Revealed a positive incline in incorporating digital orthodontics in their routine practice. However, a lack was observed in practicing digital orthodontics among Orthodontists and Orthodontic Residents of Gujarat Statistically significant difference was present regarding the awareness about digital orthodontics between males and females (p value = 0.042).\u0000Conclusion: Orthodontists and orthodontic residents of Gujarat displayed adequate knowledge, positive attitude and lack of practice about digital orthodontics. Male population is more aware about digital technologies as compared to female population.","PeriodicalId":72781,"journal":{"name":"Dental Oral Biology and Craniofacial Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42537379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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