Diabetes epidemiology and management最新文献_第3页

Sodium-glucose cotransporter 2 Inhibitors and COVID-19 outcomes in type 2 diabetes patients: A population-based cohort study 钠-葡萄糖共转运蛋白2抑制剂与2型糖尿病患者COVID-19结局：一项基于人群的队列研究

IF 1 Q4 ENDOCRINOLOGY & METABOLISM

Diabetes epidemiology and management

Pub Date : 2025-07-01 DOI: 10.1016/j.deman.2025.100273

Cerina Dubois , Jasjeet K Minhas-Sandhu , Wajd Alkabbani , Jason R.B. Dyck , Dean T. Eurich

Introduction

Sodium-glucose cotransporter 2 (SGLT2) inhibitors (SGLT-2i) have been suggested to be beneficial in the management of Coronavirus disease 2019 (COVID-19); however, animal and clinical data have been inconsistent. The objective of this study was to assess the risk of SARS-CoV-2 infection and poor COVID-19-related outcomes associated with SGLT-2i use in patients with type 2 diabetes.

Methods

This is a comparative population-based retrospective cohort study on new users of SGLT-2i or dipeptidyl peptidase-4 (DPP-4) inhibitors (DPP-4i) from January 1, 2012 to March 31, 2021 in Alberta, Canada. We assessed: 1) presence of a positive COVID-19 test (or seropositivity for SARS-CoV-2); 2) an all-cause event around positive COVID-19 test (hospital admission, emergency department visit, death); and 3) a COVID-19-specific-event(hospital admission, emergency department visit, death) around positive COVID-19 test. We estimated the hazard ratio (HR) and 95% Confidence interval (CI) using a conditional Cox proportional hazard regression after 1:1 high-dimensional propensity score (hdPS) matching.

Results

There were 37,079 SGLT-2i and 39,053 DPP-4i users (30,433 matched pairs). After adjustment, compared to DPP-4i, SGLT-2i use was minimally associated with a positive COVID-19 test [HR: 1.23; 95% CI: 1.02–1.49]. Results were statistically significant across secondary cohort comparators for the risk of a COVID-19-positive test. SGLT-2i was also associated with a higher risk in a COVID-19-specific event [HR: 1.66; 95% CI: 1.12–2.45] compared to DPP-4i.

Conclusion

SGLT-2i may be associated with a modest increase in positive COVID-19 tests across all compactors and COVID-19-specific events compared to DPP-4i among adults with type 2 diabetes. However, the clinical impact of this finding is uncertain. There is a need for further prospective studies to assess the relationship between SGLT-2i use and COVID-19-related outcomes in patients with type 2 diabetes.

钠-葡萄糖共转运蛋白2 （SGLT2）抑制剂（SGLT-2i）被认为对2019冠状病毒病（COVID-19）的治疗有益；然而，动物和临床数据并不一致。本研究的目的是评估与2型糖尿病患者使用SGLT-2i相关的SARS-CoV-2感染风险和与covid -19相关的不良预后。方法：这是一项基于比较人群的回顾性队列研究，研究对象是2012年1月1日至2021年3月31日在加拿大阿尔伯塔省新使用SGLT-2i或二肽基肽酶-4 （DPP-4）抑制剂（DPP-4i）的患者。我们评估了：1)COVID-19检测阳性（或SARS-CoV-2血清阳性）；2)围绕COVID-19检测阳性的全因事件（住院、急诊、死亡）；3)与COVID-19检测阳性相关的COVID-19特定事件（住院、急诊、死亡）。在1:1高维倾向评分（hdPS）匹配后，我们使用条件Cox比例风险回归估计了风险比（HR）和95%置信区间（CI）。结果SGLT-2i用户37,079人，DPP-4i用户39,053人（配对对30,433对）。调整后，与DPP-4i相比，SGLT-2i的使用与COVID-19检测阳性的相关性最小[HR: 1.23；95% ci: 1.02-1.49]。二级队列比较者的covid -19阳性检测风险结果具有统计学意义。SGLT-2i也与covid -19特异性事件的高风险相关[HR: 1.66；95% CI: 1.12-2.45]与DPP-4i相比。结论与DPP-4i相比，sglt -2i可能与成人2型糖尿病患者中所有压实器中COVID-19阳性试验和COVID-19特异性事件的适度增加有关。然而，这一发现的临床影响尚不确定。需要进一步的前瞻性研究来评估2型糖尿病患者使用SGLT-2i与covid -19相关结局之间的关系。

{"title":"Sodium-glucose cotransporter 2 Inhibitors and COVID-19 outcomes in type 2 diabetes patients: A population-based cohort study","authors":"Cerina Dubois , Jasjeet K Minhas-Sandhu , Wajd Alkabbani , Jason R.B. Dyck , Dean T. Eurich","doi":"10.1016/j.deman.2025.100273","DOIUrl":"10.1016/j.deman.2025.100273","url":null,"abstract":"<div><h3>Introduction</h3><div>Sodium-glucose cotransporter 2 (SGLT2) inhibitors (SGLT-2i) have been suggested to be beneficial in the management of Coronavirus disease 2019 (COVID-19); however, animal and clinical data have been inconsistent. The objective of this study was to assess the risk of SARS-CoV-2 infection and poor COVID-19-related outcomes associated with SGLT-2i use in patients with type 2 diabetes.</div></div><div><h3>Methods</h3><div>This is a comparative population-based retrospective cohort study on new users of SGLT-2i or dipeptidyl peptidase-4 (DPP-4) inhibitors (DPP-4i) from January 1, 2012 to March 31, 2021 in Alberta, Canada. We assessed: 1) presence of a positive COVID-19 test (or seropositivity for SARS-CoV-2); 2) an all-cause event around positive COVID-19 test (hospital admission, emergency department visit, death); and 3) a COVID-19-specific-event(hospital admission, emergency department visit, death) around positive COVID-19 test. We estimated the hazard ratio (HR) and 95% Confidence interval (CI) using a conditional Cox proportional hazard regression after 1:1 high-dimensional propensity score (hdPS) matching.</div></div><div><h3>Results</h3><div>There were 37,079 SGLT-2i and 39,053 DPP-4i users (30,433 matched pairs). After adjustment, compared to DPP-4i, SGLT-2i use was minimally associated with a positive COVID-19 test [HR: 1.23; 95% CI: 1.02–1.49]. Results were statistically significant across secondary cohort comparators for the risk of a COVID-19-positive test. SGLT-2i was also associated with a higher risk in a COVID-19-specific event [HR: 1.66; 95% CI: 1.12–2.45] compared to DPP-4i.</div></div><div><h3>Conclusion</h3><div>SGLT-2i may be associated with a modest increase in positive COVID-19 tests across all compactors and COVID-19-specific events compared to DPP-4i among adults with type 2 diabetes. However, the clinical impact of this finding is uncertain. There is a need for further prospective studies to assess the relationship between SGLT-2i use and COVID-19-related outcomes in patients with type 2 diabetes.</div></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"19 ","pages":"Article 100273"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of dietary patterns with anxiety, depression, and stress in patients with type 2 diabetes: a cross-sectional study 2型糖尿病患者饮食模式与焦虑、抑郁和压力的关系：一项横断面研究

IF 1 Q4 ENDOCRINOLOGY & METABOLISM

Diabetes epidemiology and management

Pub Date : 2025-06-04 DOI: 10.1016/j.deman.2025.100269

Sajedeh sadat moghaddam , Fateme Cheshmi , Narges Shahnazi , Poorya Basafa-Roodi , Mohammad Hasan Sohouli , Marzie Zilaee

Background

psychiatric problems such as depression, anxiety, and stress are common among patients with type 2 diabetes. Dietary patterns are more likely to have an essential role in the control of diabetes and its complications.

Objective

This study was conducted to assess the associations between dietary patterns with psychological parameters, and fasting blood sugar in patients with type 2 diabetes mellitus.

Methods

This cross-sectional study involved 419 men and women with type 2 diabetes aged between 25–50 years old from five health centers in Arak City, Iran. Anthropometric indices and fasting blood sugar were measured and a 168-item food frequency questionnaire (FFQ) was collected for the extraction of main dietary patterns.

Result

We found that adhering to a healthy dietary pattern was associated with a lower risk to stress (odds ratio: 0.31, 95% confidence interval: 0.13-0.72 P-trend= 0.002) while adhering to a western dietary pattern linked to higher fasting blood glucose (odds ratio: 2.25, 95% confidence interval: 1.00-5.06 P-trend= 0.039) after taking into account for confounding factors by ANCOVA. We found no significant correlation between the dietary patterns and both anxiety and depression.

Conclusion

It seems that in patients with type 2 diabetes, following a healthy dietary pattern is more likely to inversely associated with the risk of stress and hyperglycemia.

精神问题，如抑郁、焦虑和压力在2型糖尿病患者中很常见。饮食模式更有可能在控制糖尿病及其并发症方面发挥重要作用。目的探讨2型糖尿病患者饮食模式与心理参数及空腹血糖的关系。方法：这项横断面研究涉及来自伊朗阿拉克市5个健康中心的419名年龄在25-50岁之间的2型糖尿病男性和女性。测定人体测量指标和空腹血糖，并收集168项食物频率问卷（FFQ），提取主要膳食模式。结果经方差分析发现，坚持健康饮食模式与较低的应激风险相关（优势比：0.31,95%可信区间：0.13-0.72 p趋势= 0.002），而坚持西方饮食模式与较高的空腹血糖相关（优势比：2.25,95%可信区间：1.00-5.06 p趋势= 0.039）。我们发现饮食模式与焦虑和抑郁之间没有显著的相关性。结论在2型糖尿病患者中，遵循健康的饮食模式更可能与应激和高血糖的风险呈负相关。

{"title":"Association of dietary patterns with anxiety, depression, and stress in patients with type 2 diabetes: a cross-sectional study","authors":"Sajedeh sadat moghaddam , Fateme Cheshmi , Narges Shahnazi , Poorya Basafa-Roodi , Mohammad Hasan Sohouli , Marzie Zilaee","doi":"10.1016/j.deman.2025.100269","DOIUrl":"10.1016/j.deman.2025.100269","url":null,"abstract":"<div><h3>Background</h3><div>psychiatric problems such as depression, anxiety, and stress are common among patients with type 2 diabetes. Dietary patterns are more likely to have an essential role in the control of diabetes and its complications.</div></div><div><h3>Objective</h3><div>This study was conducted to assess the associations between dietary patterns with psychological parameters, and fasting blood sugar in patients with type 2 diabetes mellitus.</div></div><div><h3>Methods</h3><div>This cross-sectional study involved 419 men and women with type 2 diabetes aged between 25–50 years old from five health centers in Arak City, Iran. Anthropometric indices and fasting blood sugar were measured and a 168-item food frequency questionnaire (FFQ) was collected for the extraction of main dietary patterns.</div></div><div><h3>Result</h3><div>We found that adhering to a healthy dietary pattern was associated with a lower risk to stress (odds ratio: 0.31, 95% confidence interval: 0.13-0.72 P-trend= 0.002) while adhering to a western dietary pattern linked to higher fasting blood glucose (odds ratio: 2.25, 95% confidence interval: 1.00-5.06 P-trend= 0.039) after taking into account for confounding factors by ANCOVA. We found no significant correlation between the dietary patterns and both anxiety and depression.</div></div><div><h3>Conclusion</h3><div>It seems that in patients with type 2 diabetes, following a healthy dietary pattern is more likely to inversely associated with the risk of stress and hyperglycemia.</div></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"19 ","pages":"Article 100269"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144297589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diabetes in patients with incident acute myocardial infarction: characteristics, frequency, treatment and complications in a population-based sample 突发急性心肌梗死患者的糖尿病：以人群为基础的样本的特征、频率、治疗和并发症

IF 1 Q4 ENDOCRINOLOGY & METABOLISM

Diabetes epidemiology and management

Pub Date : 2025-06-04 DOI: 10.1016/j.deman.2025.100270

Timo Schmitz , Simone Fischer , Philip Raake , Jakob Linseisen , Christine Meisinger

Objective

To investigate predictors of a diabetes diagnosis after an acute myocardial infarction (AMI) and to examine characteristics, preventive measures, treatment and complications of diabetic AMI patients.

Methods

AMI patients registered by the Myocardial Infarction Registry Augsburg between 2017 and 2019 (n = 1.712) received a postal questionnaire in 2023 with questions on diabetes status, diabetes care and diabetes related complications (response: 50.1 %). Logistic regression models were calculated to identify predictors related to a subsequent diabetes diagnosis after first-time AMI. For diabetic patients, important characteristics of diabetes care and the frequency of complications were examined. Additionally, it was examined which diabetic AMI patients were aware of the interconnection between diabetes and AMI.

Results

A total of 200 patients (27.4 %) that responded to the survey had diabetes, 40 of them received the diagnosis after first-time hospitalized AMI. Body mass index (BMI) [OR: 1.13 [1.05–1.21], p value: 0.001] and blood glucose levels [OR: 1.01 [1.00–1.02], p value: 0.007] at hospital admission were independent predictors of a diagnosis of diabetes during follow-up. Three quarters of diabetic AMI patients knew their current HbA1c value (median 6.9 %; IQR: 6.2–7.4 %). Only 40 (23 %) patients with diabetes were aware of the interconnection between diabetes and AMI.

Conclusion

BMI and admission blood glucose were predictors of diabetes after AMI. Based on HbA1c values, overall glycemic control needs improvements in many patients. Less than a quarter of diabetic AMI patients were aware of the relationship between diabetes and AMI which emphasizes the need for specific education of these patients.

目的探讨急性心肌梗死（AMI）后糖尿病诊断的预测因素，探讨糖尿病性AMI患者的特点、预防措施、治疗及并发症。方法2017年至2019年在奥格斯堡心肌梗死登记处登记的sami患者（n = 1.712）于2023年收到一份邮寄问卷，问卷内容包括糖尿病状况、糖尿病护理和糖尿病相关并发症（应答率：50.1%）。计算逻辑回归模型以确定与首次AMI后后续糖尿病诊断相关的预测因素。对于糖尿病患者，检查糖尿病护理的重要特征和并发症的发生频率。此外，还检查了哪些糖尿病性AMI患者意识到糖尿病与AMI之间的联系。结果200例（27.4%）患者为糖尿病患者，其中40例为首次住院AMI患者。入院时体重指数（BMI） [OR: 1.13 [1.05-1.21]， p值：0.001]和血糖水平[OR: 1.01 [1.00-1.02]， p值：0.007]是随访期间糖尿病诊断的独立预测因子。四分之三的糖尿病AMI患者知道自己当前的HbA1c值(中位6.9%；（比例：6.2 - 7.4%）。只有40例（23%）糖尿病患者意识到糖尿病与AMI之间的联系。结论bmi和入院血糖是AMI后糖尿病的预测指标。根据HbA1c值，许多患者的总体血糖控制需要改善。不到四分之一的糖尿病性AMI患者了解糖尿病与AMI之间的关系，这强调了对这些患者进行特殊教育的必要性。

{"title":"Diabetes in patients with incident acute myocardial infarction: characteristics, frequency, treatment and complications in a population-based sample","authors":"Timo Schmitz , Simone Fischer , Philip Raake , Jakob Linseisen , Christine Meisinger","doi":"10.1016/j.deman.2025.100270","DOIUrl":"10.1016/j.deman.2025.100270","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate predictors of a diabetes diagnosis after an acute myocardial infarction (AMI) and to examine characteristics, preventive measures, treatment and complications of diabetic AMI patients.</div></div><div><h3>Methods</h3><div>AMI patients registered by the Myocardial Infarction Registry Augsburg between 2017 and 2019 (<em>n</em> = 1.712) received a postal questionnaire in 2023 with questions on diabetes status, diabetes care and diabetes related complications (response: 50.1 %). Logistic regression models were calculated to identify predictors related to a subsequent diabetes diagnosis after first-time AMI. For diabetic patients, important characteristics of diabetes care and the frequency of complications were examined. Additionally, it was examined which diabetic AMI patients were aware of the interconnection between diabetes and AMI.</div></div><div><h3>Results</h3><div>A total of 200 patients (27.4 %) that responded to the survey had diabetes, 40 of them received the diagnosis after first-time hospitalized AMI. Body mass index (BMI) [OR: 1.13 [1.05–1.21], p value: 0.001] and blood glucose levels [OR: 1.01 [1.00–1.02], p value: 0.007] at hospital admission were independent predictors of a diagnosis of diabetes during follow-up. Three quarters of diabetic AMI patients knew their current HbA1c value (median 6.9 %; IQR: 6.2–7.4 %). Only 40 (23 %) patients with diabetes were aware of the interconnection between diabetes and AMI.</div></div><div><h3>Conclusion</h3><div>BMI and admission blood glucose were predictors of diabetes after AMI. Based on HbA1c values, overall glycemic control needs improvements in many patients. Less than a quarter of diabetic AMI patients were aware of the relationship between diabetes and AMI which emphasizes the need for specific education of these patients.</div></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"19 ","pages":"Article 100270"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144271235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comments on the impact of oral health on fasting blood sugar levels in diabetic individuals 口腔健康对糖尿病患者空腹血糖水平的影响

IF 1 Q4 ENDOCRINOLOGY & METABOLISM

Diabetes epidemiology and management

Pub Date : 2025-06-02 DOI: 10.1016/j.deman.2025.100271

Shu Yuan , Zi-Lin Li , Jing Hu

引用次数: 0

The impact of oral health on fasting blood sugar levels in diabetic individuals: insights from the PERSIAN Guilan cohort study 口腔健康对糖尿病患者空腹血糖水平的影响：来自波斯桂兰队列研究的见解

IF 1 Q4 ENDOCRINOLOGY & METABOLISM

Diabetes epidemiology and management

Pub Date : 2025-05-18 DOI: 10.1016/j.deman.2025.100268

Amir Valaei-Barhagh , Mohammad Samami , Farahnaz Joukar , Soheil Hassanipour , Saqar Zaker , Maryam Rabiei , Mohammad Reza Naghipour , Fariborz Mansour-Ghanaei

Background

Managing diabetes and its complications is a global health priority. Inflammation exacerbates diabetes and contributes to complications such as periodontitis. This study investigates the impact of oral hygiene practices on fasting blood sugar (FBS) levels in diabetic individuals, focusing on the role of inflammation.

Methods

This cross-sectional study analyzed data from 2365 diabetic participants without dentures in the PERSIAN Guilan Cohort Study. Oral health variables included tooth brushing frequency, flossing, mouthwash usage, and DMFT scores. Diabetes status was classified based on FBS test results and/or self-report of physician-diagnosed diabetes and/or hypoglycemic drug use. Statistical analyses included ANOVA, Pearson correlation, and linear regression.

Results

Diabetic individuals who did not brush their teeth had significantly higher FBS levels (mean FBS: 153.82 mg/dL) compared to those brushing once daily (138.48 mg/dL, p = 0.006). A lower frequency of tooth brushing was associated with higher FBS levels (β = -2.994, p = 0.017). The DMFT score was positively correlated with FBS (Pearson correlation = 0.057, p = 0.005). Flossing and mouthwash usage were not significantly associated with FBS levels.

Conclusion

Enhancing oral health is particularly crucial for individuals with diabetes, as it can lead to improved glycemic control. However, it is essential to interpret these findings with caution due to the potential influence of confounding factors.

管理糖尿病及其并发症是一项全球卫生优先事项。炎症会加重糖尿病，并导致牙周炎等并发症。本研究调查了口腔卫生习惯对糖尿病患者空腹血糖（FBS）水平的影响，重点是炎症的作用。方法本横断面研究分析了波斯桂兰队列研究中2365名无义齿糖尿病患者的数据。口腔健康变量包括刷牙频率、牙线、漱口水的使用和DMFT评分。根据FBS测试结果和/或医生诊断的糖尿病和/或使用降糖药物的自我报告对糖尿病状态进行分类。统计分析包括方差分析、Pearson相关分析和线性回归分析。结果不刷牙的糖尿病患者的FBS水平（平均153.82 mg/dL）明显高于每天刷牙一次的糖尿病患者（138.48 mg/dL, p = 0.006）。刷牙频率越低，FBS水平越高（β = -2.994, p = 0.017）。DMFT评分与FBS呈正相关（Pearson相关= 0.057,p = 0.005）。使用牙线和漱口水与FBS水平无显著相关性。结论加强口腔健康对糖尿病患者尤为重要，因为它可以改善血糖控制。然而，由于混杂因素的潜在影响，谨慎解释这些发现是至关重要的。

{"title":"The impact of oral health on fasting blood sugar levels in diabetic individuals: insights from the PERSIAN Guilan cohort study","authors":"Amir Valaei-Barhagh , Mohammad Samami , Farahnaz Joukar , Soheil Hassanipour , Saqar Zaker , Maryam Rabiei , Mohammad Reza Naghipour , Fariborz Mansour-Ghanaei","doi":"10.1016/j.deman.2025.100268","DOIUrl":"10.1016/j.deman.2025.100268","url":null,"abstract":"<div><h3>Background</h3><div>Managing diabetes and its complications is a global health priority. Inflammation exacerbates diabetes and contributes to complications such as periodontitis. This study investigates the impact of oral hygiene practices on fasting blood sugar (FBS) levels in diabetic individuals, focusing on the role of inflammation.</div></div><div><h3>Methods</h3><div>This cross-sectional study analyzed data from 2365 diabetic participants without dentures in the PERSIAN Guilan Cohort Study. Oral health variables included tooth brushing frequency, flossing, mouthwash usage, and DMFT scores. Diabetes status was classified based on FBS test results and/or self-report of physician-diagnosed diabetes and/or hypoglycemic drug use. Statistical analyses included ANOVA, Pearson correlation, and linear regression.</div></div><div><h3>Results</h3><div>Diabetic individuals who did not brush their teeth had significantly higher FBS levels (mean FBS: 153.82 mg/dL) compared to those brushing once daily (138.48 mg/dL, <em>p</em> = 0.006). A lower frequency of tooth brushing was associated with higher FBS levels (β = -2.994, <em>p</em> = 0.017). The DMFT score was positively correlated with FBS (Pearson correlation = 0.057, <em>p</em> = 0.005). Flossing and mouthwash usage were not significantly associated with FBS levels.</div></div><div><h3>Conclusion</h3><div>Enhancing oral health is particularly crucial for individuals with diabetes, as it can lead to improved glycemic control. However, it is essential to interpret these findings with caution due to the potential influence of confounding factors.</div></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"19 ","pages":"Article 100268"},"PeriodicalIF":1.0,"publicationDate":"2025-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144139230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Caregiver knowledge of hypoglycemia and hyperglycemia management in children and adolescents with type 1 diabetes 儿童和青少年1型糖尿病患者低血糖和高血糖管理的护理知识

IF 1 Q4 ENDOCRINOLOGY & METABOLISM

Diabetes epidemiology and management

Pub Date : 2025-05-16 DOI: 10.1016/j.deman.2025.100267

Matthew Feldman , Grace PS Kwong , Josephine Ho

Objective

To determine the current knowledge of the assessment and management of acute diabetes-related complications including severe hypoglycemia and diabetic ketoacidosis (DKA) among caregivers of patients with type 1 diabetes (T1D).

Methods

A cross-sectional survey was completed at a tertiary care pediatric hospital diabetes clinic from November 2021 to July 2022. Data was analyzed from all completed survey responses and included both Likert and evaluation-style questions.

Results

A total of 152 surveys were collected and 96 were included in the analysis. Caregiver knowledge on management of hypoglycemia was significantly better than their knowledge on hyperglycemia management (median score 100 % vs 60 %, p-value <0.001). There was no difference in caregiver knowledge around assessment of hypoglycemia or hyperglycemia (median score 88.9 % vs 88.9 %, p-value 0.909). There was no significant difference in overall knowledge as determined by percentage of questions correct between those on different blood glucose monitors (p-value 0.184) or whether the parent/caregiver or the patient were primarily responsible for T1D management (p-value 0.964). There was no difference in total score by management type when adjusted using the Bonferroni method. There was also no significant interaction by level of caregiver involvement.

Conclusions

Caregiver knowledge of management of hypoglycemia was significantly better than their knowledge of management of hyperglycemia in pediatric T1D. Blood glucose monitoring or T1D management type was not found to be associated with any differences in caregiver knowledge in the assessment or management of hypoglycemia or hyperglycemia.

目的了解1型糖尿病（T1D）患者护理人员对严重低血糖和糖尿病酮症酸中毒（DKA）等急性糖尿病相关并发症的评估和管理现状。方法于2021年11月至2022年7月在某三级儿科医院糖尿病门诊完成横断面调查。数据分析来自所有完成的调查回答，包括李克特和评估式问题。结果共收集问卷152份，其中96份纳入分析。护理人员低血糖管理知识显著优于高血糖管理知识（中位数评分100% vs 60%， p值<；0.001）。护理人员对低血糖或高血糖评估的知识没有差异（中位数得分88.9% vs 88.9%， p值0.909）。使用不同血糖监测仪的患者在总体知识上的正确率没有显著差异（p值0.184），父母/照顾者或患者是否主要负责T1D的管理（p值0.964）。采用Bonferroni方法调整后，各管理类型的总分无差异。照顾者参与程度也没有显著的相互作用。结论护理人员对小儿T1D低血糖处理的知识明显优于对高血糖处理的知识。血糖监测或T1D管理类型未发现与护理人员在低血糖或高血糖评估或管理方面的知识差异相关。

{"title":"Caregiver knowledge of hypoglycemia and hyperglycemia management in children and adolescents with type 1 diabetes","authors":"Matthew Feldman , Grace PS Kwong , Josephine Ho","doi":"10.1016/j.deman.2025.100267","DOIUrl":"10.1016/j.deman.2025.100267","url":null,"abstract":"<div><h3>Objective</h3><div>To determine the current knowledge of the assessment and management of acute diabetes-related complications including severe hypoglycemia and diabetic ketoacidosis (DKA) among caregivers of patients with type 1 diabetes (T1D).</div></div><div><h3>Methods</h3><div>A cross-sectional survey was completed at a tertiary care pediatric hospital diabetes clinic from November 2021 to July 2022. Data was analyzed from all completed survey responses and included both Likert and evaluation-style questions.</div></div><div><h3>Results</h3><div>A total of 152 surveys were collected and 96 were included in the analysis. Caregiver knowledge on management of hypoglycemia was significantly better than their knowledge on hyperglycemia management (median score 100 % vs 60 %, p-value <0.001). There was no difference in caregiver knowledge around assessment of hypoglycemia or hyperglycemia (median score 88.9 % vs 88.9 %, p-value 0.909). There was no significant difference in overall knowledge as determined by percentage of questions correct between those on different blood glucose monitors (p-value 0.184) or whether the parent/caregiver or the patient were primarily responsible for T1D management (p-value 0.964). There was no difference in total score by management type when adjusted using the Bonferroni method. There was also no significant interaction by level of caregiver involvement.</div></div><div><h3>Conclusions</h3><div>Caregiver knowledge of management of hypoglycemia was significantly better than their knowledge of management of hyperglycemia in pediatric T1D. Blood glucose monitoring or T1D management type was not found to be associated with any differences in caregiver knowledge in the assessment or management of hypoglycemia or hyperglycemia.</div></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"19 ","pages":"Article 100267"},"PeriodicalIF":1.0,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144139231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of various psychotic disorders among patients with type 2 diabetes: Real-world evidence from Shanghai, China 2型糖尿病患者中各种精神障碍的患病率：来自中国上海的真实世界证据

IF 1 Q4 ENDOCRINOLOGY & METABOLISM

Diabetes epidemiology and management

Pub Date : 2025-04-01 DOI: 10.1016/j.deman.2025.100259

Yunxi Ji , Ping He , Yingxia Zhou , Huayan Yao , Yanbin Xue , Renjie Jing , Tingyu Zhang , Wen Sun , Ping Lu , Bin Cui , Weiqing Wang

Aims

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder that significantly impacts psychotic health, leading to increased incidence and mortality. We aim to explore the status of patients with T2DM and the issue of comorbid psychotic disorders.

Methods

Our study estimated the characteristics of 836,120 patients with T2DM from 2019 to 2023 based on electronic health records from the Shanghai Link Database (SHLD). We calculated the prevalence of the four major psychotic disorders in patients with T2DM, including depression, anxiety, dementia, and schizophrenia. The data was also stratified by age, sex, and other factors. Additionally, the association between diabetes complications and various psychotic disorders was investigated.

Results

We observed that the age group of 55-80 counted for about 68.15% of the total population with T2DM. There were more male patients with T2DM than females, but females exhibited a higher overall prevalence of psychotic disorders compared to males. For patients with T2DM, anxiety had the highest prevalence (3.97%), followed by depression (2.33%), dementia (2.04%), and schizophrenia (0.16%). There was a significant relationship between psychotic disorders and various diabetes complications.

Conclusions

The high prevalence of psychotic disorders among patients with T2DM highlights the importance of considering the impact of their comorbid psychotic illnesses when treating T2DM. Developing high-quality diabetes healthcare and implementing targeted treatment and management plans are essential in addressing these issues.

目的：2型糖尿病（T2DM）是一种慢性代谢紊乱，严重影响精神健康，导致发病率和死亡率增加。我们的目的是探讨T2DM患者的状况和共病性精神障碍的问题。方法基于上海Link数据库（SHLD）的电子健康记录，对2019 - 2023年836,120例T2DM患者的特征进行估计。我们计算了T2DM患者中四种主要精神障碍的患病率，包括抑郁、焦虑、痴呆和精神分裂症。数据还按年龄、性别和其他因素分层。此外，还研究了糖尿病并发症与各种精神障碍之间的关系。结果55 ~ 80岁年龄组占T2DM患者总数的68.15%。男性2型糖尿病患者多于女性，但女性精神障碍的总体患病率高于男性。在T2DM患者中，焦虑患病率最高（3.97%），其次是抑郁（2.33%）、痴呆（2.04%）和精神分裂症（0.16%）。精神障碍与各种糖尿病并发症之间存在显著相关性。结论T2DM患者中精神疾病的高发突出了在治疗T2DM时考虑其合并症精神疾病影响的重要性。发展高质量的糖尿病保健和实施有针对性的治疗和管理计划对于解决这些问题至关重要。

{"title":"Prevalence of various psychotic disorders among patients with type 2 diabetes: Real-world evidence from Shanghai, China","authors":"Yunxi Ji , Ping He , Yingxia Zhou , Huayan Yao , Yanbin Xue , Renjie Jing , Tingyu Zhang , Wen Sun , Ping Lu , Bin Cui , Weiqing Wang","doi":"10.1016/j.deman.2025.100259","DOIUrl":"10.1016/j.deman.2025.100259","url":null,"abstract":"<div><h3>Aims</h3><div>Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder that significantly impacts psychotic health, leading to increased incidence and mortality. We aim to explore the status of patients with T2DM and the issue of comorbid psychotic disorders.</div></div><div><h3>Methods</h3><div>Our study estimated the characteristics of 836,120 patients with T2DM from 2019 to 2023 based on electronic health records from the Shanghai Link Database (SHLD). We calculated the prevalence of the four major psychotic disorders in patients with T2DM, including depression, anxiety, dementia, and schizophrenia. The data was also stratified by age, sex, and other factors. Additionally, the association between diabetes complications and various psychotic disorders was investigated.</div></div><div><h3>Results</h3><div>We observed that the age group of 55-80 counted for about 68.15% of the total population with T2DM. There were more male patients with T2DM than females, but females exhibited a higher overall prevalence of psychotic disorders compared to males. For patients with T2DM, anxiety had the highest prevalence (3.97%), followed by depression (2.33%), dementia (2.04%), and schizophrenia (0.16%). There was a significant relationship between psychotic disorders and various diabetes complications.</div></div><div><h3>Conclusions</h3><div>The high prevalence of psychotic disorders among patients with T2DM highlights the importance of considering the impact of their comorbid psychotic illnesses when treating T2DM. Developing high-quality diabetes healthcare and implementing targeted treatment and management plans are essential in addressing these issues.</div></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"18 ","pages":"Article 100259"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143894994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The rise in incidence of pediatric type 2 diabetes during the COVID-19 pandemic and the virus as a potential causative factor COVID-19大流行期间儿童2型糖尿病发病率的上升以及该病毒作为潜在的致病因素

IF 1 Q4 ENDOCRINOLOGY & METABOLISM

Diabetes epidemiology and management

Pub Date : 2025-01-24 DOI: 10.1016/j.deman.2025.100258

Andrew Kanouse , Joanna S. Fishbein , Parissa Salemi

Aim

The prevalence of type 2 diabetes continues to rise across multiple demographics but there was an especially large increase in incidence during the COVID-19 pandemic. A pre-existing diagnosis of type 2 diabetes is generally associated with more difficulties with viral infections, as seen with COVID-19, but it is less clear if a reverse causal association exists between the development of type 2 diabetes and infection with the COVID-19 virus. Our aim was to determine if an association exists between the COVID-19 virus and new diagnoses of pediatric type 2 diabetes.

Methods

We examined 130 new patients in our pediatric endocrinology practice diagnosed with type 2 diabetes immediately before and just after the emergence of the pandemic to determine if there was a change in presenting characteristics between these two periods.

Results

Our data showed an increase in the incidence of type 2 diabetes (p < 0.0001) and a lower mean presenting age (p = 0.03) during the COVID-19 pandemic without differences in other parameters.

Conclusion

We believe these results suggest that the development of type 2 diabetes following COVID-19 infection is due to mechanisms inherent to the virus itself and that younger patients are especially at an increased risk.

多种人口统计数据显示，2型糖尿病的患病率持续上升，但在2019冠状病毒病大流行期间，发病率增幅尤其大。如COVID-19所示，先前的2型糖尿病诊断通常与病毒感染的更多困难相关，但2型糖尿病的发展与COVID-19病毒感染之间是否存在反向因果关系尚不清楚。我们的目的是确定COVID-19病毒与儿童2型糖尿病的新诊断之间是否存在关联。方法我们在小儿内分泌科的实践中检查了130例新诊断为2型糖尿病的患者，这些患者在大流行出现之前和之后不久被诊断为2型糖尿病，以确定这两个时期之间的表现特征是否有变化。结果我们的数据显示2型糖尿病的发病率增加(p <；0.0001)和较低的平均呈现年龄（p = 0.03），在COVID-19大流行期间，其他参数无差异。结论我们认为，这些结果表明，COVID-19感染后2型糖尿病的发展是由于病毒本身固有的机制，特别是年轻患者的风险增加。

{"title":"The rise in incidence of pediatric type 2 diabetes during the COVID-19 pandemic and the virus as a potential causative factor","authors":"Andrew Kanouse , Joanna S. Fishbein , Parissa Salemi","doi":"10.1016/j.deman.2025.100258","DOIUrl":"10.1016/j.deman.2025.100258","url":null,"abstract":"<div><h3>Aim</h3><div>The prevalence of type 2 diabetes continues to rise across multiple demographics but there was an especially large increase in incidence during the COVID-19 pandemic. A pre-existing diagnosis of type 2 diabetes is generally associated with more difficulties with viral infections, as seen with COVID-19, but it is less clear if a reverse causal association exists between the development of type 2 diabetes and infection with the COVID-19 virus. Our aim was to determine if an association exists between the COVID-19 virus and new diagnoses of pediatric type 2 diabetes.</div></div><div><h3>Methods</h3><div>We examined 130 new patients in our pediatric endocrinology practice diagnosed with type 2 diabetes immediately before and just after the emergence of the pandemic to determine if there was a change in presenting characteristics between these two periods.</div></div><div><h3>Results</h3><div>Our data showed an increase in the incidence of type 2 diabetes (<em>p</em> < 0.0001) and a lower mean presenting age (<em>p</em> = 0.03) during the COVID-19 pandemic without differences in other parameters.</div></div><div><h3>Conclusion</h3><div>We believe these results suggest that the development of type 2 diabetes following COVID-19 infection is due to mechanisms inherent to the virus itself and that younger patients are especially at an increased risk.</div></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"18 ","pages":"Article 100258"},"PeriodicalIF":1.0,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143128747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of diabetes-related sarcopenia and its defining components within primary care: A cross-sectional study 初级保健中糖尿病相关肌肉减少症的患病率及其定义成分：一项横断面研究

IF 1 Q4 ENDOCRINOLOGY & METABOLISM

Diabetes epidemiology and management

Pub Date : 2025-01-23 DOI: 10.1016/j.deman.2025.100252

Rubén Silva-Tinoco , Lilia Castillo-Martínez , Berenice Cabrera-Victoria , Eileen Guzmán-Olvera , Christian Hinojosa-Segura , Alejandro Avalos-Bracho , Cira Santillán-Díaz

Background

Diabetes-related sarcopenia is a significant contributor to the global prevalence of sarcopenia. Both conditions become more prevalent with age and amplify the risk of adverse outcomes. This study aimed to assess the prevalence of sarcopenia and at-risk morphofunctional (MF) phenotypes and to identify the factors associated in patients with type 2 diabetes (T2D), including non-elderly adults, in primary care settings

Methods

This cross-sectional study included 261 individuals managed in primary care units in Mexico City, between July 2022 and May 2024. Assessments followed the guidelines of the European Working Group on Sarcopenia in Older Adults (EWGSOP2) to identify isolated low muscle mass, low muscle strength, and sarcopenia or severe sarcopenia

Results

The mean age of the participants (57.1 % female) was 51.1 ± 12.1 years, with a median diabetes duration of 7 (1–15) years. An altered MF assessment was observed in 159 participants, with 14.1 % exhibiting sarcopenia, 5.4 % isolated low muscle strength, and 41.4 % isolated low muscle mass. Univariate logistic regression analysis identified that age, educational level, diabetes duration, weight, body mass index, waist circumference, hip circumference, fat mass, use, and insulin dose were associated with altered MF assessment. Multivariable analyses showed that hip circumference and hypertriglyceridemia were associated with a lower risk of altered MF assessment, whereas the interactions between age and fat mass increased the risk.

Conclusions

This primary care study, which included elderly and non-elderly adults with T2D, revealed a relatively high prevalence of altered MF assessments, including sarcopenia, low muscle strength, and low muscle mass. Early recognition of sarcopenia spectrum disorders is essential for the timely prevention of adverse outcomes related to diabetic sarcopenia in primary care settings.

背景：糖尿病相关的肌肉减少症是全球肌肉减少症流行的重要因素。这两种情况都随着年龄的增长而变得更加普遍，并增加了不良后果的风险。本研究旨在评估骨骼肌减少症和高危形态功能（MF）表型的患病率，并确定2型糖尿病（T2D）患者（包括非老年人）在初级保健机构中的相关因素。方法本横断面研究包括2022年7月至2024年5月期间在墨西哥城初级保健单位管理的261名患者。评估遵循欧洲老年人肌肉减少症工作组（EWGSOP2）的指导方针，以确定孤立的低肌肉质量，低肌肉力量和肌肉减少症或严重的肌肉减少症。结果参与者的平均年龄（57.1%为女性）为51.1±12.1岁，中位糖尿病持续时间为7（1-15）年。在159名参与者中观察到改变的MF评估，其中14.1%表现为肌肉减少症，5.4%表现为低肌肉力量，41.4%表现为低肌肉质量。单变量logistic回归分析发现，年龄、受教育程度、糖尿病病程、体重、体重指数、腰围、臀围、脂肪量、使用情况和胰岛素剂量与MF评估的改变有关。多变量分析显示，臀围和高甘油三酯血症与MF评估改变的风险较低相关，而年龄和脂肪量之间的相互作用增加了风险。结论：这项初级保健研究，包括老年和非老年T2D患者，揭示了MF评估改变的相对较高的患病率，包括肌肉减少症、低肌肉力量和低肌肉质量。早期识别肌少症谱系障碍对于及时预防初级保健机构中与糖尿病性肌少症相关的不良后果至关重要。

{"title":"Prevalence of diabetes-related sarcopenia and its defining components within primary care: A cross-sectional study","authors":"Rubén Silva-Tinoco , Lilia Castillo-Martínez , Berenice Cabrera-Victoria , Eileen Guzmán-Olvera , Christian Hinojosa-Segura , Alejandro Avalos-Bracho , Cira Santillán-Díaz","doi":"10.1016/j.deman.2025.100252","DOIUrl":"10.1016/j.deman.2025.100252","url":null,"abstract":"<div><h3>Background</h3><div>Diabetes-related sarcopenia is a significant contributor to the global prevalence of sarcopenia. Both conditions become more prevalent with age and amplify the risk of adverse outcomes. This study aimed to assess the prevalence of sarcopenia and at-risk morphofunctional (MF) phenotypes and to identify the factors associated in patients with type 2 diabetes (T2D), including non-elderly adults, in primary care settings</div></div><div><h3>Methods</h3><div>This cross-sectional study included 261 individuals managed in primary care units in Mexico City, between July 2022 and May 2024. Assessments followed the guidelines of the European Working Group on Sarcopenia in Older Adults (EWGSOP2) to identify isolated low muscle mass, low muscle strength, and sarcopenia or severe sarcopenia</div></div><div><h3>Results</h3><div>The mean age of the participants (57.1 % female) was 51.1 ± 12.1 years, with a median diabetes duration of 7 (1–15) years. An altered MF assessment was observed in 159 participants, with 14.1 % exhibiting sarcopenia, 5.4 % isolated low muscle strength, and 41.4 % isolated low muscle mass. Univariate logistic regression analysis identified that age, educational level, diabetes duration, weight, body mass index, waist circumference, hip circumference, fat mass, use, and insulin dose were associated with altered MF assessment. Multivariable analyses showed that hip circumference and hypertriglyceridemia were associated with a lower risk of altered MF assessment, whereas the interactions between age and fat mass increased the risk.</div></div><div><h3>Conclusions</h3><div>This primary care study, which included elderly and non-elderly adults with T2D, revealed a relatively high prevalence of altered MF assessments, including sarcopenia, low muscle strength, and low muscle mass. Early recognition of sarcopenia spectrum disorders is essential for the timely prevention of adverse outcomes related to diabetic sarcopenia in primary care settings.</div></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"18 ","pages":"Article 100252"},"PeriodicalIF":1.0,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143128746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of clinical pharmacists in improving diabetic care of hospitalized heart patients 临床药师在改善住院心脏病患者糖尿病护理中的作用

IF 1 Q4 ENDOCRINOLOGY & METABOLISM

Diabetes epidemiology and management

Pub Date : 2025-01-01 DOI: 10.1016/j.deman.2024.100248

Sanaa Mekdad, Leenah Alsayed, Susan Alkhulaif

Introduction

Globally, diabetes is becoming an increasingly prevalent chronic illness. Managing glucose levels in patients with diabetes presents a significant challenge that requires collaboration with medical specialists. Clinical pharmacists play a crucial role in diabetes management, positively influencing patient outcomes and improving overall quality of care.

Objectives

The purpose of this research is to understand how clinical pharmacists at King Fahad Medical City impact the management of hospitalized patients with diabetes and cardiac conditions.

Method

A prospective randomized study was conducted at the Cardiac Center of King Fahad Medical City, involving patients admitted between 2019 and 2023. Participants were assigned to one of two groups: one managed by clinical pharmacists (n = 500) and the other receiving standard care without clinical pharmacists (n = 500). Patients were followed up with six months following the clinical pharmacist's intervention, as well as concurrently with data collection, baseline measurements of glycosylated hemoglobin (HbAC), fasting blood glucose (FBG), and the frequency of hypoglycemic episodes. after intervention. Concurrently, included (HbA1c), after intervention. Concurrently, collection included (HbA1c), episodes following the

Results

Both groups demonstrated a decrease in HbA1c levels. The intervention group experienced a reduction in HbA1c from 10.2 % to 8.5 % (SD = 2.2, p = 0.04). In contrast, the control group showed a decrease in HbA1c from 9.95 % to 9.05 % (SD = 1.95, p = 0.05). Additionally, fasting blood glucose (FBG) levels in the intervention group decreased by 29 mg/dL, while the decline in the control group was not statistically significant, at 9 mg/dL. The difference in HbA1c levels was statistically significant, as determined by both t-tests.

Conclusions

As a member of a multidisciplinary team, a clinical pharmacist can play a crucial role in monitoring diabetes in hospitalized patients with heart conditions. Their interventions can more effectively lower HbA1c levels and fasting blood glucose (FBG) in these patients compared to standard care.

在全球范围内，糖尿病正在成为一种日益普遍的慢性疾病。管理糖尿病患者的血糖水平是一项重大挑战，需要与医学专家合作。临床药师在糖尿病管理中发挥着至关重要的作用，积极影响患者的预后，提高整体护理质量。目的了解法赫德国王医疗城的临床药师如何影响糖尿病和心脏病住院患者的管理。方法在法赫德国王医疗城心脏中心进行前瞻性随机研究，纳入2019年至2023年入院的患者。参与者被分配到两组中的一组：一组由临床药师管理（n = 500），另一组接受没有临床药师的标准治疗（n = 500）。在临床药师的干预下，对患者进行了为期6个月的随访，同时收集数据、糖化血红蛋白（HbAC）基线测量、空腹血糖（FBG）和低血糖发作频率。后干预。同时，纳入（HbA1c），干预后。同时，收集包括（HbA1c），以下事件。结果两组均显示HbA1c水平下降。干预组HbA1c从10.2%降至8.5% （SD = 2.2, p = 0.04）。对照组HbA1c由9.95%降至9.05% （SD = 1.95, p = 0.05）。此外，干预组的空腹血糖（FBG）水平下降了29 mg/dL，而对照组的下降无统计学意义，为9 mg/dL。两组HbA1c水平的差异均具有统计学意义。结论临床药师作为多学科团队的一员，对住院心脏病患者的糖尿病监测具有重要作用。与标准治疗相比，他们的干预措施可以更有效地降低这些患者的HbA1c水平和空腹血糖（FBG）。

{"title":"The role of clinical pharmacists in improving diabetic care of hospitalized heart patients","authors":"Sanaa Mekdad, Leenah Alsayed, Susan Alkhulaif","doi":"10.1016/j.deman.2024.100248","DOIUrl":"10.1016/j.deman.2024.100248","url":null,"abstract":"<div><h3>Introduction</h3><div>Globally, diabetes is becoming an increasingly prevalent chronic illness. Managing glucose levels in patients with diabetes presents a significant challenge that requires collaboration with medical specialists. Clinical pharmacists play a crucial role in diabetes management, positively influencing patient outcomes and improving overall quality of care.</div></div><div><h3>Objectives</h3><div>The purpose of this research is to understand how clinical pharmacists at King Fahad Medical City impact the management of hospitalized patients with diabetes and cardiac conditions.</div></div><div><h3>Method</h3><div>A prospective randomized study was conducted at the Cardiac Center of King Fahad Medical City, involving patients admitted between 2019 and 2023. Participants were assigned to one of two groups: one managed by clinical pharmacists (<em>n</em> = 500) and the other receiving standard care without clinical pharmacists (<em>n</em> = 500). Patients were followed up with six months following the clinical pharmacist's intervention, as well as concurrently with data collection, baseline measurements of glycosylated hemoglobin (HbAC), fasting blood glucose (FBG), and the frequency of hypoglycemic episodes. after intervention. Concurrently, included (HbA1c), after intervention. Concurrently, collection included (HbA1c), episodes following the</div></div><div><h3>Results</h3><div>Both groups demonstrated a decrease in HbA1c levels. The intervention group experienced a reduction in HbA1c from 10.2 % to 8.5 % (SD = 2.2, <em>p</em> = 0.04). In contrast, the control group showed a decrease in HbA1c from 9.95 % to 9.05 % (SD = 1.95, <em>p</em> = 0.05). Additionally, fasting blood glucose (FBG) levels in the intervention group decreased by 29 mg/dL, while the decline in the control group was not statistically significant, at 9 mg/dL. The difference in HbA1c levels was statistically significant, as determined by both <em>t</em>-tests.</div></div><div><h3>Conclusions</h3><div>As a member of a multidisciplinary team, a clinical pharmacist can play a crucial role in monitoring diabetes in hospitalized patients with heart conditions. Their interventions can more effectively lower HbA1c levels and fasting blood glucose (FBG) in these patients compared to standard care.</div></div>","PeriodicalId":72796,"journal":{"name":"Diabetes epidemiology and management","volume":"17 ","pages":"Article 100248"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143092415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0